Long QT syndrome, Brugada syndrome, and conduction system disease are linked to a single sodium channel mutation
Augustus O. Grant, … , Carlo Napolitano, Silvia Priori
Augustus O. Grant, … , Carlo Napolitano, Silvia Priori
Published October 15, 2002
Citation Information: J Clin Invest. 2002;110(8):1201-1209. https://doi.org/10.1172/JCI15570.
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Article

Long QT syndrome, Brugada syndrome, and conduction system disease are linked to a single sodium channel mutation

Abstract

Research Article

Authors

Augustus O. Grant, Michael P. Carboni, Valentina Neplioueva, C. Frank Starmer, Mirella Memmi, Carlo Napolitano, Silvia Priori

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EKG traces of mutation carriers showing leads V1, V2, and V5. (a) QT int...
EKG traces of mutation carriers showing leads V1, V2, and V5. (a) QT interval prolongation (patient IV-13 of the pedigree shown in Figure 1). (b) ST segment elevation (patient IV-5 of the pedigree). (c) ST segment elevation and right bundle branch block (patient IV-3 of the pedigree). (d) First-degree AV block and sinus arrest (patient III-14 of the pedigree).