T cell homeostatic proliferation elicits effective antitumor autoimmunity
Wolfgang Dummer, … , Ralph A. Reisfeld, Argyrios N. Theofilopoulos
Wolfgang Dummer, … , Ralph A. Reisfeld, Argyrios N. Theofilopoulos
Published July 15, 2002
Citation Information: J Clin Invest. 2002;110(2):185-192. https://doi.org/10.1172/JCI15175.
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T cell homeostatic proliferation elicits effective antitumor autoimmunity

Abstract

Research Article

Authors

Wolfgang Dummer, Andreas G. Niethammer, Roberto Baccala, Brian R. Lawson, Norbert Wagner, Ralph A. Reisfeld, Argyrios N. Theofilopoulos

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Effect of homeostatic T cell expansion on growth of a colon carcinoma ce...
Effect of homeostatic T cell expansion on growth of a colon carcinoma cell line. Sublethally irradiated C57BL/6 mice were challenged subcutaneously with 105 MC-38 colon carcinoma cells, and half of the mice were transfused with 5 × 107 B6 LN cells. Tumor growth was inhibited in the transfused (triangles) compared with the nontransfused (squares) mice (both groups, n = 6).