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Sabra L. Klein, … , Arturo Casadevall, Aaron A.R. Tobian
Published August 7, 2020
Citation Information: J Clin Invest. 2020;130(11):6141-6150. https://doi.org/10.1172/JCI142004.
Citation Information: J Clin Invest. 2020;130(11):6141-6150. https://doi.org/10.1172/JCI142004.
Abstract
Convalescent plasma is a leading treatment for coronavirus disease 2019 (COVID-19), but there is a paucity of data identifying its therapeutic efficacy. Among 126 potential convalescent plasma donors, the humoral immune response was evaluated using a severe acute respiratory syndrome coronavirus 2 (SARS–CoV-2) virus neutralization assay with Vero-E6-TMPRSS2 cells; a commercial IgG and IgA ELISA to detect the spike (S) protein S1 domain (EUROIMMUN); IgA, IgG, and IgM indirect ELISAs to detect the full-length S protein or S receptor–binding domain (S-RBD); and an IgG avidity assay. We used multiple linear regression and predictive models to assess the correlations between antibody responses and demographic and clinical characteristics. IgG titers were greater than either IgM or IgA titers for S1, full-length S, and S-RBD in the overall population. Of the 126 plasma samples, 101 (80%) had detectable neutralizing antibody (nAb) titers. Using nAb titers as the reference, the IgG ELISAs confirmed 95%–98% of the nAb-positive samples, but 20%–32% of the nAb-negative samples were still IgG ELISA positive. Male sex, older age, and hospitalization for COVID-19 were associated with increased antibody responses across the serological assays. There was substantial heterogeneity in the antibody response among potential convalescent plasma donors, but sex, age, and hospitalization emerged as factors that can be used to identify individuals with a high likelihood of having strong antiviral antibody responses.
Authors
Sabra L. Klein, Andrew Pekosz, Han-Sol Park, Rebecca L. Ursin, Janna R. Shapiro, Sarah E. Benner, Kirsten Littlefield, Swetha Kumar, Harnish Mukesh Naik, Michael J. Betenbaugh, Ruchee Shrestha, Annie A. Wu, Robert M. Hughes, Imani Burgess, Patricio Caturegli, Oliver Laeyendecker, Thomas C. Quinn, David Sullivan, Shmuel Shoham, Andrew D. Redd, Evan M. Bloch, Arturo Casadevall, Aaron A.R. Tobian
Citation information
Citations to this article (345)
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Klein S, Dhakal S, Yin A, Escarra-Senmarti M, Demko Z, Pisanic N, Johnston T, Trejo-Zambrano M, Kruczynski K, Lee J, Hardick J, Shea P, Shapiro J, Park HS, Parish M, Caputo C, Ganesan A, Mullapudi S, Gould S, Betenbaugh M, Pekosz A, Heaney CD, Antar A, Manabe Y, Cox A, Karaba A, Andrade F, Zeger S |
Research square | 2023 |
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Predictors of public attitudes in Saudi Arabia toward people who stutter
Al Awaji NN, Alfouzan RF, Almutairi AR, Mortada EM |
PloS one | 2023 |
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SARS-CoV-2 Humoral Immune Responses in Convalescent Individuals Over 12 Months Reveal Severity-Dependent Antibody Dynamics
Siles N, Schuler M, Maguire C, Amengor D, Nguyen A, Wilen R, Rogers J, Bazzi S, Caslin B, DiPasquale C, Abigania M, Olson E, Creaturo J, Hurley K, Triplett TA, Rousseau JF, Strakowski SM, Wylie D, Maynard J, Ehrlich LI, Melamed E |
2023 | |
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Pharmacokinetics of High-titer Anti-SARS-CoV-2 Human Convalescent Plasma in High-risk Children
Oren Gordon, Mary K. Brosnan, Steve Yoon, Dawoon Jung, Kirsten Littlefield, Abhinaya Ganesan, Christopher A. Caputo, Maggie Li, William Morgenlander, Stephanie N. Henson, Alvaro A. Ordonez, Patricia De Jesus, Elizabeth W. Tucker, Nadine Peart Akindele, Zexu Ma, Jo Wilson, Camilo A. Ruiz-Bedoya, M. Elizabeth M. Younger, Evan M Bloch, Shmuel Shoham, David Sullivan, Aaron A.R. Tobian, Kenneth R. Cooke, Ben Larman, Jogarao Gobburu, Arturo Casadevall, Andrew Pekosz, Howard M Lederman, Sabra Klein, Sanjay K. Jain |
JCI Insight | 2022 |
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Immune Sexual Dimorphism: Connecting the Dots
S Gal-Oz, T Shay |
Physiology (Bethesda, Md.) | 2022 |
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Endothelial thrombomodulin downregulation caused by hypoxia contributes to severe infiltration and coagulopathy in COVID-19 patient lungs
T Won, M Wood, D Hughes, M Talor, Z Ma, J Schneider, J Skinner, B Asady, E Goerlich, M Halushka, A Hays, D Kim, C Parikh, A Rosenberg, I Coppens, R Johns, N Gilotra, J Hooper, A Pekosz, D Čiháková |
EBioMedicine | 2022 |
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Clinical and analytical evaluation of the Abbott AdviseDx quantitative SARS-CoV-2 IgG assay and comparison with two other serological tests
G Maine, S Krishnan, K Walewski, J Trueman, E Sykes, Q Sun |
Journal of Immunological Methods | 2022 |
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Antibody attributes that predict the neutralization and effector function of polyclonal responses to SARS-CoV-2
H Natarajan, S Xu, A Crowley, S Butler, J Weiner, E Bloch, K Littlefield, S Benner, R Shrestha, O Ajayi, W Wieland-Alter, D Sullivan, S Shoham, T Quinn, A Casadevall, A Pekosz, A Redd, A Tobian, R Connor, P Wright, M Ackerman |
BMC Immunology | 2022 |
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Antibody profiles in COVID ‐19 convalescent plasma prepared with amotosalen/ UVA pathogen reduction treatment
A Bagri, R Assis, C Tsai, G Simmons, Z Mei, M Goetz, M Gatmaitan, M Stone, C Germanio, R Martinelli, O Darst, J Rioveros, P Robinson, D Ward, A Ziman, D Seftel, S Khan, M Busch, P Felgner, L Corash |
Transfusion | 2022 |
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Early Outpatient Treatment for Covid-19 with Convalescent Plasma
D Sullivan, K Gebo, S Shoham, E Bloch, B Lau, A Shenoy, G Mosnaim, T Gniadek, Y Fukuta, B Patel, S Heath, A Levine, B Meisenberg, E Spivak, S Anjan, M Huaman, J Blair, J Currier, J Paxton, J Gerber, J Petrini, P Broderick, W Rausch, M Cordisco, J Hammel, B Greenblatt, V Cluzet, D Cruser, K Oei, M Abinante, L Hammitt, C Sutcliffe, D Forthal, M Zand, E Cachay, J Raval, S Kassaye, E Foster, M Roth, C Marshall, A Yarava, K Lane, N McBee, A Gawad, N Karlen, A Singh, D Ford, D Jabs, L Appel, D Shade, S Ehrhardt, S Baksh, O Laeyendecker, A Pekosz, S Klein, A Casadevall, A Tobian, D Hanley |
New England Journal of Medicine | 2022 |
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Sexual dimorphism in COVID-19: potential clinical and public health implications
N Bechmann, A Barthel, A Schedl, S Herzig, Z Varga, C Gebhard, M Mayr, C Hantel, F Beuschlein, C Wolfrum, N Perakakis, L Poston, C Andoniadou, R Siow, R Gainetdinov, A Dotan, Y Shoenfeld, G Mingrone, S Bornstein |
The Lancet Diabetes & Endocrinology | 2022 |
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Humoral response to SARS-CoV-2 infection among liver transplant recipients
C Becchetti, A Broekhoven, G Dahlqvist, M Fraga, M Zambelli, O Ciccarelli, A Saouli, A Trizzino, V Banz, J Dufour, A Roukens, S Morales, S Myeni, M Kikkert, M Feltkamp, M Coenraad |
Gut | 2022 |
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Prediction of mortality in hospitalized Egyptian patients with Coronavirus disease-2019: A multicenter retrospective study
M AbdelGhaffar, D Omran, A Elgebaly, E Bahbah, S Afify, M AlSoda, M El-Shiekh, E ElSayed, S Shaaban, S AbdelHafez, K Elkelany, A Eltayar, O Ali, L Kamal, A Heiba, A Askary, H Shousha, P Mitra |
PloS one | 2022 |
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Lessons learned from the use of convalescent plasma for the treatment of COVID-19 and specific considerations for immunocompromised patients
M Beraud, E Meyer, M Lozano, A Bah, R Vassallo, B Brown |
Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis | 2022 |
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Dynamic 3D radiomics analysis using artificial intelligence to assess the stage of COVID-19 on CT images
S Cai, Y Chen, S Zhao, D He, Y Li, N Xiong, Z Li, S Hu |
European Radiology | 2022 |
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A prospective study of the impact of glycaemic status on clinical outcomes and anti-SARS-CoV-2 antibody responses among patients with predominantly non-severe COVID-19
D Lui, Y Li, C Lee, W Chow, A Lee, A Tam, P Pang, T Ho, C Cheung, C Fong, K To, K Tan, Y Woo, I Hung, K Lam |
Diabetes Research and Clinical Practice | 2022 |
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SARS-CoV-2 Vaccines: Safety and Immunogenicity in Solid Organ Transplant Recipients and Strategies for Improving Vaccine Responses
A Grupper, H Katchman |
Current Transplantation Reports | 2022 |
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Spike-Dependent Opsonization Indicates Both Dose-Dependent Inhibition of Phagocytosis and That Non-Neutralizing Antibodies Can Confer Protection to SARS-CoV-2
W Bahnan, S Wrighton, M Sundwall, A Bläckberg, O Larsson, U Höglund, H Khakzad, M Godzwon, M Walle, Elisabeth, A Strand, L Happonen, O André, J Ahnlide, T Hellmark, V Wendel-Hansen, R Wallin, J Malmstöm, L Malmström, M Ohlin, M Rasmussen, P Nordenfelt |
Frontiers in immunology | 2022 |
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Limited Variation between SARS-CoV-2-Infected Individuals in Domain Specificity and Relative Potency of the Antibody Response against the Spike Glycoprotein
H Ert, D Bohan, K Rogers, M Fili, R Chávez, E Qing, C Han, S Dempewolf, G Hu, N Schwery, K Sevcik, N Ruggio, D Boyt, M Pentella, T Gallagher, J Jackson, A Merrill, C Knudson, G Brown, W Maury, H Haim, B He |
Microbiology spectrum | 2022 |
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Three Specific Potential Epitopes That Could Be Recognized by T Cells of Convalescent COVID-19 Patients Were Identified From Spike Protein
Y Zhang, Z Yang, M Tang, H Li, T Tang, G Li, Y Zhong, X Zhang, X Wang, C Wang |
Frontiers in immunology | 2022 |
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Durable T-cellular and humoral responses in SARS-CoV-2 hospitalized and community patients
K Mohn, G Bredholt, F Zhou, A Madsen, T Onyango, E Fjelltveit, S Jalloh, K Brokstad, D Cantoni, M Mayora-Neto, N Temperton, N Langeland, R Cox, J Das |
PloS one | 2022 |
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Rapid, High Throughput, Automated Detection Of SARS-Cov-2 Neutralizing Antibodies Against Native-Like Vaccine And Delta Variant Spike Trimers
Narayanaiah Cheedarla, Hans Verkerke, Sindhu Potlapalli, Kaleb McLendon, Anamika Patel, Filipp Frank, Gregory Damhorst, Huixia Wu, William O'Sick, Daniel Graciaa, Fuad Hudaib, David Alter, Jeannette Bryksin, Eric Ortlund, Jeannette Guarner, Sara Auld, Sarita Shah, Wilbur Lam, Dawn Mattoon, Joseph Johnson, David Wilson, Madhav Dhodapkar, Sean Stowell, Andrew Neish, John Roback |
Research square | 2022 |
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Immune mechanisms associated with sex-based differences in severe COVID-19 clinical outcomes
C Arnold, A Libby, A Vest, A Hopkinson, A Monte |
Biology of sex differences | 2022 |
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Long-term immune responses in patients with confirmed novel coronavirus disease-2019: a 9-month prospective cohort study in Shanghai, China
X Gong, P Cui, H Wu, H Pan, Z Teng, F Yuan, S Mao, D Kong, R Han, X Zhao, Y Zheng, W Xiao, Y Zhu, Q Fang, S Lin, B Jin, R Chu, C Jiang, X Yu, Q Qiu, Y Lu, W Wang, C Fu, X Sun |
BMC Infectious Diseases | 2022 |
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Differentiation of Individuals Previously Infected with and Vaccinated for SARS-CoV-2 in an Inner-City Emergency Department
E Beck, Y Hsieh, R Fernandez, G Dashler, E Egbert, S Truelove, C Garliss, R Wang, E Bloch, R Shrestha, J Blankson, A Cox, Y Manabe, T Kickler, R Rothman, A Redd, A Tobian, A Milstone, T Quinn, O Laeyendecker, Y Tang |
Journal of clinical microbiology | 2022 |
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Boosting of cross-reactive antibodies to endemic coronaviruses by SARS-CoV-2 infection but not vaccination with stabilized spike
A Crowley, H Natarajan, A Hederman, C Bobak, J Weiner, W Wieland-Alter, J Lee, E Bloch, A Tobian, A Redd, J Blankson, D Wolf, T Goetghebuer, A Marchant, R Connor, P Wright, M Ackerman |
eLife | 2022 |
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Associations Between Symptoms, Donor Characteristics and IgG Antibody Response in 2082 COVID-19 Convalescent Plasma Donors
M Vinkenoog, M Steenhuis, A ten Brinke, J van Hasselt, M Janssen, M van Leeuwen, F Swaneveld, H Vrielink, L van de Watering, F Quee, K van den Hurk, T Rispens, B Hogema, C van der Schoot |
Frontiers in immunology | 2022 |
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Minimal Crossover between Mutations Associated with Omicron Variant of SARS-CoV-2 and CD8 + T-Cell Epitopes Identified in COVID-19 Convalescent Individuals
A Redd, A Nardin, H Kared, E Bloch, B Abel, A Pekosz, O Laeyendecker, M Fehlings, T Quinn, A Tobian, S Goff |
mBio | 2022 |
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The feasibility of multiple units of convalescent plasma in mechanically ventilated patients with COVID-19: A pilot study
N Merin, A LeVee, C Merlo, K Spector, H Coleman, E Klapper, C Hayes, R Zabner, J McDyer, Y Eby, D Sullivan, A Tobian, E Bloch, D Hager |
Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis | 2022 |
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Avidity of IgG to SARS-CoV-2 RBD as a Prognostic Factor for the Severity of COVID-19 Reinfection
V Manuylov, O Burgasova, O Borisova, S Smetanina, D Vasina, I Grigoriev, A Kudryashova, M Semashko, B Cherepovich, O Kharchenko, D Kleymenov, E Mazunina, A Tkachuk, V Gushchin |
Viruses | 2022 |
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Higher Proinflammatory Cytokines Are Associated With Increased Antibody Titer After a Third Dose of SARS-CoV-2 Vaccine in Solid Organ Transplant Recipients
A Karaba, X Zhu, S Benner, O Akinde, Y Eby, K Wang, S Saraf, J Garonzik-Wang, S Klein, J Bailey, A Cox, J Blankson, C Durand, D Segev, W Werbel, A Tobian |
Transplantation | 2022 |
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Improving the specificity of nucleic acid detection with endonuclease-actuated degradation
R Zou, M Gavrilov, Y Liu, D Rasoloson, M Conte, J Hardick, L Shen, S Chen, A Pekosz, G Seydoux, Y Manabe, T Ha |
2022 | |
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A cohort study measuring SARS-CoV-2 seroconversion and serial viral testing in university students
C Lee, H Segaloff, D Cole, H Rosenblum, C Morgan, T Somers, R Desamu-Thorpe, M Foster, D Currie, J Ruff, D Payne, T Whyte, G Abedi, J Bigouette, J Kahrs, K Langolf, P Remington, A Sterkel, P Kelly, R Westergaard, A Bateman, C Hsu, J Tate, H Kirking |
BMC Infectious Diseases | 2022 |
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Humoral Response to the Third Dose of Sars-Cov-2 Vaccine in Kidney Transplant Recipients
A Grupper, L Rabinowich, M Ben-Yehoyada, E Katchman, R Baruch, T Freund, D Hagin, S Shlomo, D Schwartz, I Schwartz, M Shashar, O Bassat, T Halperin, D Turner, E Saiag, Y Goykhman, O Shibolet, S Levy, I Houri, H Katchman |
Transplantation Proceedings | 2022 |
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SARS-CoV-2 Antibody Response Is Associated with Age and Body Mass Index in Convalescent Outpatients
B Zhai, K Clarke, D Bauer, K Geffel, S Kupul, L Schratz, M Nowalk, A McElroy, J McLachlan, R Zimmerman, J Alcorn |
Journal of immunology (Baltimore, Md. : 1950) | 2022 |
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A third dose of SARS‐CoV‐2 vaccine increases neutralizing antibodies against variants of concern in solid organ transplant recipients
A Karaba, X Zhu, T Liang, K Wang, A Rittenhouse, O Akinde, Y Eby, J Ruff, J Blankson, A Abedon, J Alejo, A Cox, J Bailey, E Thompson, S Klein, D Warren, J GaronzikWang, B Boyarsky, I Sitaras, A Pekosz, D Segev, A Tobian, W Werbel |
American Journal of Transplantation | 2022 |
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Measurements of SARS-CoV-2 antibody dissociation rate constant by chaotrope-free biolayer interferometry in serum of COVID-19 convalescent patients
Y Hao, H Yang, M Karbaschi, S Racine-Brzostek, P Li, R Zuk, Y Yang, P Klasse, Y Shi, Z Zhao |
Biosensors & bioelectronics | 2022 |
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Dynamic observation of SARS‐CoV‐2 IgM, IgG, and neutralizing antibodies in the development of population immunity through COVID‐19 vaccination
R Jiang, X Dou, M Li, E Wang, J Hu, D Xiong, X Zhang |
Journal of Clinical Laboratory Analysis | 2022 |
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Estimating the Neutralizing Effect and Titer Correlation of Semi-Quantitative Anti-SARS-CoV-2 Antibody Immunoassays
B Lee, J Ko, J Park, H Moon, J Baek, S Jung, H Lim, K Kim, K Huh, S Cho, C Kang, D Chung, H Huh, C Chung, Y Kim, E Joo, E Kang, K Peck |
Frontiers in Cellular and Infection Microbiology | 2022 |
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Sex Differences in Clinical Characteristics and Outcomes of Patients with SARS-CoV-2-Infection Admitted to Intensive Care Units in Austria
A Kautzky-Willer, M Kaleta, S Lindner, M Leutner, S Thurner, P Klimek |
Journal of Personalized Medicine | 2022 |
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Convalescent plasma for COVID ‐19: Donor demographic factors associated high neutralising antibody titres
J Mehew, R Johnson, D Roberts, A Griffiths, H Harvala |
Transfusion Medicine | 2022 |
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SARS‐CoV‐2 antibody testing for transplant recipients: A tool to personalize protection versus COVID‐19
W Werbel, D Segev |
American Journal of Transplantation | 2022 |
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Serological study of CoronaVac vaccine and booster doses in Chile: immunogenicity and persistence of anti-SARS-CoV-2 spike antibodies
Vargas L, Valdivieso N, Tempio F, Simon V, Sauma D, Valenzuela L, Beltrán C, Castillo-Delgado L, Contreras-Benavides X, Acevedo ML, Acevedo J, Gonzalez RI, Valiente-Echeverría F, Soto-Rifo R, Rosemblatt M, Lopez M, Osorio F, Bono MR |
BMC Medicine | 2022 |
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Convalescent plasma with a high level of virus-specific antibody effectively neutralizes SARS-CoV-2 variants of concern
Li M, Beck EJ, Laeyendecker O, Eby Y, Tobian AA, Caturegli P, Wouters C, Chiklis GR, Block W, McKie RO, Joyner MJ, Wiltshire TD, Dietz AB, Gniadek TJ, Shapiro AJ, Yarava A, Lane K, Hanley DF, Bloch EM, Shoham S, Cachay ER, Meisenberg BR, Huaman MA, Fukuta Y, Patel B, Heath SL, Levine AC, Paxton JH, Anjan S, Gerber JM, Gebo KA, Casadevall A, Pekosz A, Sullivan DJ |
Blood Advances | 2022 |
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Neutralising activity and antibody titre in 10 patients with breakthrough infections of the SARS-CoV-2 Omicron variant in Japan
Okumura N, Tsuzuki S, Saito S, Hattori SI, Takeuchi JS, Saito T, Ujiie M, Hojo M, Iwamoto N, Sugiura W, Mitsuya H, Ohmagari N |
Journal of Infection and Chemotherapy | 2022 |
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Mission, Organization, and Future Direction of the Serological Sciences Network for COVID-19 (SeroNet) Epidemiologic Cohort Studies
Figueiredo JC, Hirsch FR, Kushi LH, Nembhard WN, Crawford JM, Mantis N, Finster L, Merin NM, Merchant A, Reckamp KL, Melmed GY, Braun J, McGovern D, Parekh S, Corley DA, Zohoori N, Amick BC, Du R, Gregersen PK, Diamond B, Taioli E, Sariol C, Espino A, Weiskopf D, Gifoni A, Brien J, Hanege W, Lipsitch M, Zidar DA, Scheck McAlearney A, Wajnberg A, LaBaer J, Yvonne Lewis E, Binder RA, Moormann AM, Forconi C, Forrester S, Batista J, Schieffelin J, Kim D, Biancon G, VanOudenhove J, Halene S, Fan R, Barouch DH, Alter G, Pinninti S, Boppana SB, Pati SK, Latting M, Karaba AH, Roback J, Sekaly R, Neish A, Brincks AM, Granger DA, Karger AB, Thyagarajan B, Thomas SN, Klein SL, Cox AL, Lucas T, Furr-Holden D, Key K, Jones N, Wrammerr J, Suthar M, Yu Wong S, Bowman NM, Simon V, Richardson LD, McBride R, Krammer F, Rana M, Kennedy J, Boehme K, Forrest C, Granger SW, Heaney CD, Knight Lapinski M, Wallet S, Baric RS, Schifanella L, Lopez M, Fernández S, Kenah E, Panchal AR, Britt WJ, Sanz I, Dhodapkar M, Ahmed R, Bartelt LA, Markmann AJ, Lin JT, Hagan RS, Wolfgang MC, Skarbinski J |
Open Forum Infectious Diseases | 2022 |
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The Impact of Age and Gender and Their Association with Chemosensory Dysfunction, in Hospitalized and Self-Quarantine Patients with Covid-19 Infection, in Epirus, Greece
ZARACHI A, PEZOULAS V, MILIONIS O, LIANOU AN, KLOURAS E, KOMNOS I, FOTIADIS D, KASTANIOUDAKIS I, MILIONIS C, LIONTOS A |
Mædica | 2022 |
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Differential antibody production by symptomatology in SARS-CoV-2 convalescent individuals
Saraf S, Zhu X, Shrestha R, Bonny TS, Baker OR, Beck EJ, Fernandez RE, Eby Y, Akinde O, Ruff JE, Caturegli P, Redd AD, Bloch EM, Quinn TC, Tobian AA, Laeyendecker O |
PloS one | 2022 |
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Production and Quality Assurance of Human Polyclonal Hyperimmune Immunoglobulins Against SARS-CoV-2
Burnouf T, Gathof B, Bloch EM, Bazin R, de Angelis V, Patidar GK, Rastvorceva RM, Oreh A, Goel R, Rahimi-Levene N, Hindawi S, Al-Riyami AZ, So-Osman C |
Transfusion Medicine Reviews | 2022 |
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A systematic review and meta-analysis of the IgA seroprevalence in COVID-19 patients: Is there a role for IgA in COVID-19 diagnosis or severity?
Rangel-Ramírez VV, Macías-Piña KA, Servin-Garrido RR, de Alba-Aguayo DR, Moreno-Fierros L, Rubio-Infante N |
Microbiological research | 2022 |
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Factors associated with death in COVID-19 patients over 60 years of age at Kinshasa University Hospital, Democratic Republic of Congo (DRC)
Bepouka B, Mandina M, Longokolo M, Mayasi N, Odio O, Mangala D, Mafuta Y, Makulo JR, Mbula M, Kayembe JM, Situakibanza H |
The Pan African medical journal | 2022 |
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Evaluation of SARS-CoV-2 antibody persistence and viral spread in stool: a long-term care experience before COVID-19 vaccination
Eren-Kutsoylu OO, Appak O, Nazli-Zeka A, Omeroglu-Simsek G, Tekin N, Bayram B, Sayiner AA, Tanglay N, Avkan-Oguz V |
Irish Journal of Medical Science | 2022 |
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Kinetics of anti-nucleocapsid IgG response in COVID-19 immunocompetent convalescent patients
Movsisyan M, Chopikyan A, Kasparova I, Hakobjanyan G, Carrat F, Sukiasyan M, Rushanyan M, Chalabyan M, Shariff S, Kantawala B, Keshishyan A, Hovhannisyan A, Hakobyan A, Petrosyan G, Minasyan A, Muradyan A, Mekinian A, Yenkoyan K |
Scientific Reports | 2022 |
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Virus Infection and Systemic Inflammation: Lessons Learnt from COVID-19 and Beyond
Faist A, Janowski J, Kumar S, Hinse S, Çalışkan DM, Lange J, Ludwig S, Brunotte L |
Cells | 2022 |
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COVID-19 and plasma cells: Is there long-lived protection?
Nguyen DC, Lamothe PA, Woodruff MC, Saini AS, Faliti CE, Sanz I, Lee FE |
Immunological Reviews | 2022 |
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Differential avidity determination of IgG directed towards the receptor‐binding domain (RBD) of SARS‐CoV‐2 wild‐type and its variants in one assay: Rational tool for the assessment of protective immunity
Bauer G, Struck F, Staschik E, Maile J, Wochinz\u2010Richter K, Motz M, Soutschek E |
Journal of Medical Virology | 2022 |
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Brief Research Report: Virus-Specific Humoral Immunity at Admission Predicts the Development of Respiratory Failure in Unvaccinated SARS-CoV-2 Patients
Tajuelo A, Carretero O, García-Ríos E, López-Siles M, Cano O, Vázquez M, Más V, Rodríguez-Goncer I, Lalueza A, López-Medrano F, San Juan R, Fernández-Ruiz M, Aguado JM, McConnell MJ, Pérez-Romero P |
Frontiers in immunology | 2022 |
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The SARS-CoV-2 Variant Omicron Is Able to Escape Vaccine-Induced Humoral Immune Responses, but Is Counteracted by Booster Vaccination
Hastert FD, Hein S, von Rhein C, Benz NI, Husria Y, Oberle D, Maier TJ, Hildt E, Schnierle BS |
Human vaccines | 2022 |
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Influence of a Heterologous (ChAdOx1-nCoV-19/BNT162b2) or Homologous (BNT162b2/BNT162b2) Vaccination Regimen on the Antibody and T Cell Response to a Third Vaccination with BNT162b2
Reiter R, Von Blanckenburg P, Mutters R, Thiemer J, Geßner R, Seifart U |
Human vaccines | 2022 |
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Humoral Immunogenicity of the mRNA-1273 Vaccine in the Phase 3 Coronavirus Efficacy (COVE) Trial
El Sahly HM, Baden LR, Essink B, Montefiori D, McDermont A, Rupp R, Lewis M, Swaminathan S, Griffin C, Fragoso V, Miller VE, Girard B, Paila YD, Deng W, Tomassini JE, Paris R, Schödel F, Das R, August A, Leav B, Miller JM, Zhou H, Pajon R |
The Journal of Infectious Diseases | 2022 |
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Plasmonic Fluor-Enhanced Antigen Arrays for High-Throughput, Serological Studies of SARS-CoV-2
Qavi AJ, Wu C, Lloyd M, Zaman MM, Luan J, Ballman C, Leung DW, Crick SL, Farnsworth CW, Amarasinghe GK |
ACS Infectious Diseases | 2022 |
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My story of sex, gender, and women's health in a pandemic
Klein SL |
Immunological Reviews | 2022 |
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Analysis of 52 240 source plasma donors of convalescent COVID‐19 plasma: Sex, ethnicity, and age association with initial antibody levels and rate of dissipation
Schmidt AE, Vogel P, Chastain CA, Barnes T, Roth NJ, Simon TL |
Journal of Clinical Apheresis | 2022 |
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Association of Frailty, Age, and Biological Sex With Severe Acute Respiratory Syndrome Coronavirus 2 Messenger RNA Vaccine-Induced Immunity in Older Adults.
Shapiro JR, Sitaras I, Park HS, Aytenfisu TY, Caputo C, Li M, Lee J, Johnston TS, Li H, Wouters C, Hauk P, Jacobsen H, Li Y, Abrams E, Yoon S, Kocot AJ, Yang T, Huang Y, Cramer SM, Betenbaugh MJ, Debes AK, Morgan R, Milstone AM, Karaba AH, Pekosz A, Leng SX, Klein SL |
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America | 2022 |
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Analysis of anti-Omicron neutralizing antibody titers in different convalescent plasma sources
Focosi D, Franchini M, Joyner MJ, Casadevall A, Sullivan DJ |
2022 | |
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Kinetics of severe acute respiratory syndrome coronavirus 2 infection antibody responses
Lin Y, Zhu J, Liu Z, Li C, Guo Y, Wang Y, Chen K |
Frontiers in immunology | 2022 |
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Unbiased discovery of autoantibodies associated with severe COVID-19 via genome-scale self-assembled DNA-barcoded protein libraries.
Credle JJ, Gunn J, Sangkhapreecha P, Monaco DR, Zheng XA, Tsai HJ, Wilbon A, Morgenlander WR, Rastegar A, Dong Y, Jayaraman S, Tosi L, Parekkadan B, Baer AN, Roederer M, Bloch EM, Tobian AAR, Zyskind I, Silverberg JI, Rosenberg AZ, Cox AL, Lloyd T, Mammen AL, Benjamin Larman H |
Nature Biomedical Engineering | 2022 |
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The Serological Sciences Network (SeroNet) for COVID-19: Depth and Breadth of Serology Assays and Plans for Assay Harmonization
Karger AB, Brien JD, Christen JM, Dhakal S, Kemp TJ, Klein SL, Pinto LA, Premkumar L, Roback JD, Binder RA, Boehme KW, Boppana S, Cordon-Cardo C, Crawford JM, Daiss JL, Dupuis AP II, Espino AM, Firpo-Betancourt A, Forconi C, Forrest JC, Girardin RC, Granger DA, Granger SW, Haddad NS, Heaney CD, Hunt DT, Kennedy JL, King CL, Krammer F, Kruczynski K, LaBaer J, Lee FE, Lee WT, Liu SL, Lozanski G, Lucas T, Mendu DR, Moormann AM, Murugan V, Okoye NC, Pantoja P, Payne AF, Park J, Pinninti S, Pinto AK, Pisanic N, Qiu J, Sariol CA, Simon V, Song L, Steffen TL, Stone ET, Styer LM, Suthar MS, Thomas SN, Thyagarajan B, Wajnberg A, Yates JL, Sobhani K |
mSphere | 2022 |
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A Pilot Study to Examine If Dietary Habits Can Affect Symptomology in Mild Pre-Vaccination COVID-19 Cases.
McDaid KM, Chopra M |
Biology | 2022 |
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Seroprevalence of SARS-CoV-2 infection in the Tyrolean district of Schwaz at the time of the rapid mass vaccination in March 2021 following B.1.351-variant outbreak.
Willeit P, Kimpel J, Winner H, Harthaller T, Schäfer H, Bante D, Falkensammer B, Rössler A, Riepler L, Ower C, Sacher M, von Laer D, Borena W |
Frontiers in public health | 2022 |
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Differences in systemic and mucosal SARS-CoV-2 antibody prevalence in a prospective cohort of Dutch children.
Keuning MW, Grobben M, Bijlsma MW, Anker B, Berman-de Jong EP, Cohen S, Felderhof M, de Groen AE, de Groof F, Rijpert M, van Eijk HWM, Tejjani K, van Rijswijk J, Steenhuis M, Rispens T, Plötz FB, van Gils MJ, Pajkrt D |
Frontiers in immunology | 2022 |
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Clinical Practice Guidelines From the Association for the Advancement of Blood and Biotherapies (AABB): COVID-19 Convalescent Plasma
Estcourt LJ, Cohn CS, Pagano MB, Iannizzi C, Kreuzberger N, Skoetz N, Allen ES, Bloch EM, Beaudoin G, Casadevall A, Devine DV, Foroutan F, Gniadek TJ, Goel R, Gorlin J, Grossman BJ, Joyner MJ, Metcalf RA, Raval JS, Rice TW, Shaz BH, Vassallo RR, Winters JL, Tobian AA |
Annals of internal medicine | 2022 |
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Immunity After Vaccination Against SARS-CoV-2 in Lung Transplant?
López GM, Moralejo RA, Roncal MP, Ortiz MT, Loaiza CA, Rivilla AP, Gafas AD |
Transplantation Proceedings | 2022 |
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Convalescent Plasma in Older Adults with COVID-19: A Systematic Review and Meta-Analysis
Aryana IG, Daniella D, Paulus IB, Rini SS, Setiati S |
Annals of Geriatric Medicine and Research | 2022 |
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Analysis of anti-SARS-CoV-2 Omicron-neutralizing antibody titers in different vaccinated and unvaccinated convalescent plasma sources.
Sullivan DJ, Franchini M, Joyner MJ, Casadevall A, Focosi D |
Nature Communications | 2022 |
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Neutralizing SARS-CoV-2 Spike Antibodies against Omicron in Paired Samples after Two or Three Doses of mRNA Vaccine.
Debes AK, Xiao S, Egbert ER, Caturegli P, Gadala A, Colantuoni E, Sitaras I, Pekosz A, Milstone AM |
Microbiology spectrum | 2022 |
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Evaluation of commercially available fully automated and ELISA-based assays for detecting anti-SARS-CoV-2 neutralizing antibodies.
Zedan HT, Yassine HM, Al-Sadeq DW, Liu N, Qotba H, Nicolai E, Pieri M, Bernardini S, Abu-Raddad LJ, Nasrallah GK |
Scientific Reports | 2022 |
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The BBIBP-CorV inactivated COVID-19 vaccine induces robust and persistent humoral responses to SARS-CoV-2 nucleocapsid, besides spike protein in healthy adults.
Wang Q, Ning J, Chen Y, Li B, Shi L, He T, Zhang F, Chen X, Zhai A, Wu C |
Frontiers in microbiology | 2022 |
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The Comparative Superiority of SARS-CoV-2 Antibody Response in Different Immunization Scenarios
Kotsiou OS, Karakousis N, Papagiannis D, Matsiatsiou E, Avgeri D, Fradelos EC, Siachpazidou DI, Perlepe G, Miziou A, Kyritsis A, Gogou E, Vavougios GD, Kalantzis G, Gourgoulianis KI |
Journal of Personalized Medicine | 2022 |
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SARS-CoV-2 IgG Levels Allow Predicting the Optimal Time Span of Convalescent Plasma Donor Suitability
Laner-Plamberger S, Lindlbauer N, Weidner L, Gänsdorfer S, Weseslindtner L, Held N, Lauth W, Zimmermann G, Kern JM, Föttinger F, Ombres L, Jungbauer C, Rohde E, Grabmer C |
Diagnostics | 2022 |
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Effects of Exercise on COVID-19 Patients: A Narrative Review
Varpaei HA, Khafaee pour Khamseh A, Hashemi A, Mohammadi M, Mohammadi P |
Medical journal of the Islamic Republic of Iran | 2022 |
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Mucosal and Systemic Responses to Severe Acute Respiratory Syndrome Coronavirus 2 Vaccination Determined by Severity of Primary Infection
Sajadi MM, Myers A, Logue J, Saadat S, Shokatpour N, Quinn J, Newman M, Deming M, Rikhtegaran Tehrani Z, Magder LS, Karimi M, Abbasi A, Shlyak M, Baracco L, Frieman MB, Crotty S, Harris AD |
mSphere | 2022 |
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The D614G mutation redirects SARS-CoV-2 spike to lysosomes and suppresses deleterious traits of the furin cleavage site insertion mutation.
Guo C, Tsai SJ, Ai Y, Li M, Anaya E, Pekosz A, Cox A, Gould SJ |
Science Advances | 2022 |
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Sex Differences in Immunity
Wilkinson NM, Chen HC, Lechner MG, Su MA |
Annual Review of Immunology | 2022 |
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Absence of pathogenic viruses in COVID-19 convalescent plasma.
Kandathil AJ, Benner SE, Bloch EM, Shrestha R, Ajayi O, Zhu X, Caturegli PP, Shoham S, Sullivan D, Gebo K, Quinn TC, Casadevall A, Hanley D, Pekosz A, Redd AD, Balagopal A, Tobian AAR |
Transfusion | 2022 |
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Kinetics of SARS-CoV-2 IgM and IgG Antibodies 3 Months after COVID-19 Onset in Moroccan Patients.
Assaid N, Arich S, Charoute H, Akarid K, Anouar Sadat M, Maaroufi A, Ezzikouri S, Sarih M |
The American journal of tropical medicine and hygiene | 2022 |
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Methodological approaches to optimize multiplex oral fluid SARS-CoV-2 IgG assay performance and correlation with serologic and neutralizing antibody responses
Pisanic N, Antar AA, Kruczynski K, Rivera MG, Dhakal S, Spicer K, Randad PR, Pekosz A, Klein SL, Betenbaugh MJ, Detrick B, Clarke W, Thomas DL, Manabe YC, Heaney CD |
2022 | |
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Reconsideration of Antinucleocapsid IgG Antibody as a Marker of SARS-CoV-2 Infection Postvaccination for Mild COVID-19 Patients
Dhakal S, Yu T, Yin A, Pisanic N, Demko ZO, Antar AA, Cox AL, Heaney CD, Manabe YC, Klein SL |
Open Forum Infectious Diseases | 2022 |
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SARS-CoV-2-specific antibody response characteristics in COVID-19 patients of different ages: SARS-CoV-2 antibody response in different aged patients
Lu L, Yu S, Liu M, Li Y, Lei Q, Lin M, Lai D, Guo S, Jiang H, Hou H, Zheng Y, Wang X, Ma M, Zhang B, Chen H, Xue J, Zhang H, Qi H, Sun Z, Wang F, Fan X, Xu Z |
Acta Biochimica et Biophysica Sinica | 2022 |
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The Serological Sciences Network (SeroNet) for COVID-19: Depth and Breadth of Serology Assays and Plans for Assay Harmonization.
Karger AB, Brien JD, Christen JM, Dhakal S, Kemp TJ, Klein SL, Pinto LA, Premkumar L, Roback JD, Binder RA, Boehme KW, Boppana S, Cordon-Cardo C, Crawford JM, Daiss JL, Dupuis AP 2nd, Espino AM, Firpo-Betancourt A, Forconi C, Forrest JC, Girardin RC, Granger DA, Granger SW, Haddad NS, Heaney CD, Hunt DT, Kennedy JL, King CL, Krammer F, Kruczynski K, LaBaer J, Lee FE, Lee WT, Liu SL, Lozanski G, Lucas T, Mendu DR, Moormann AM, Murugan V, Okoye NC, Pantoja P, Payne AF, Park J, Pinninti S, Pinto AK, Pisanic N, Qiu J, Sariol CA, Simon V, Song L, Steffen TL, Stone ET, Styer LM, Suthar MS, Thomas SN, Thyagarajan B, Wajnberg A, Yates JL, Sobhani K |
medRxiv : the preprint server for health sciences | 2022 |
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Comparison of total and neutralizing SARS-CoV-2 spike antibodies against omicron and other variants in paired samples after two or three doses of mRNA vaccine.
Debes AK, Xiao S, Egbert ER, Caturegli P, Sitaras I, Pekosz A, Milstone AM |
medRxiv : the preprint server for health sciences | 2022 |
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Differential antibody production by symptomatology in SARS-CoV-2 convalescent individuals.
Saraf S, Zhu X, Shrestha R, Bonny TS, Baker OR, Beck EJ, Fernandez RE, Eby Y, Akinde O, Ruff JE, Caturegli P, Redd AD, Bloch EM, Quinn TC, Tobian AA, Laeyendecker O |
medRxiv : the preprint server for health sciences | 2022 |
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High Viral Specific Antibody Convalescent Plasma Effectively Neutralizes SARS-CoV-2 Variants of Concern.
Li M, Beck EJ, Laeyendecker O, Eby Y, Tobian AA, Caturegli P, Wouters C, Chiklis GR, Block W, McKie R, Joyner M, Wiltshire TD, Dietz AB, Gniadek TJ, Shapiro A, Yarava A, Lane K, Hanley D, Bloch EM, Shoham S, Cachay ER, Meisenberg BR, Huaman MA, Fukuta Y, Patel B, Heath SL, Levine AC, Paxton JH, Anjan S, Gerber JM, Gebo KA, Casadevall A, Pekosz A, Sullivan DJ |
medRxiv : the preprint server for health sciences | 2022 |
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Clinical, laboratory, and temporal predictors of neutralizing antibodies to SARS-CoV-2 among COVID-19 convalescent plasma donor candidates
Jim Boonyaratanakornkit, Chihiro Morishima, Stacy Selke, Danniel Zamora, Sarah A. McGuffin, Adrienne E. Shapiro, Victoria L. Campbell, Christopher L. McClurkan, Lichen Jing, Robin Gross, Janie Liang, Elena Postnikova, Steven Mazur, Vladimir V. Lukin, Anu Chaudhary, Marie K. Das, Susan L. Fink, Andrew Bryan, Alexander L. Greninger, Keith R. Jerome, Michael R. Holbrook, Terry B. Gernsheimer, Mark H. Wener, Anna Wald, David M. Koelle |
Journal of Clinical Investigation | 2021 |
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SARS-CoV-2-specific CD8+ T cell responses in convalescent COVID-19 individuals
Hassen Kared, Andrew D Redd, Evan M. Bloch, Tania S. Bonny, Hermi R Sumatoh, Faris Kairi, Daniel Carbajo, Brian Abel, Evan W. Newell, Maria Bettinotti, Sarah E. Benner, Eshan U. Patel, Kirsten Littlefield, Oliver Laeyendecker, Shmuel Shoham, David Sullivan, Arturo Casadevall, Andrew Pekosz, Alessandra Nardin, Michael Fehlings, Aaron Tobian, Thomas C. Quinn |
Journal of Clinical Investigation | 2021 |
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Antibody responses to endemic coronaviruses modulate COVID-19 convalescent plasma functionality
William R. Morgenlander, Stephanie Henson, Daniel Monaco, Athena Chen, Kirsten Littlefield, Evan Bloch, Eric Fujimura, Ingo Ruczinski, Andrew Crowley, Harini Natarajan, Savannah Butler, Joshua Weiner, Mamie Li, Tania Bonny, Sarah Benner, Ashwin Balagopal, David Sullivan, Shmuel Shoham, Thomas Quinn, Susan Eshleman, Arturo Casadevall, Andrew Redd, Oliver Laeyendecker, Margaret Ackerman, Andrew Pekosz, Steve Elledge, Matthew Robinson, Aaron Tobian, H. Larman |
Journal of Clinical Investigation | 2021 |
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Durable SARS-CoV-2 B cell immunity after mild or severe disease
Clinton O. Ogega, Nicole E Skinner, Paul W. Blair, Han-Sol Park, Kirsten Littlefield, Abhinaya Ganesan, Santosh Dhakal, Pranay Ladiwala, Annukka A R Antar, Stuart C. Ray, Michael Betenbaugh, Andrew Pekosz, Sabra L. Klein, Yukari C. Manabe, Andrea Cox, Justin Bailey |
Journal of Clinical Investigation | 2021 |
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Relationship of SARS-CoV-2-specific CD4 response to COVID-19 severity and impact of HIV-1 and Tuberculosis co-infection
Catherine Riou, Elsa Du Bruyn, Cari Stek, Remy Daroowala, Rene Goliath, Fatima Abrahams, Qonita Said-Hartley, Brian W Allwood, Nei-yuan Hsiao, Katalin A. Wilkinson, Cecilia Lindestam Arlehamn, Alessandro Sette, Sean Wasserman, Robert J Wilkinson |
Journal of Clinical Investigation | 2021 |
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Temporal Analysis of Serial Donations Reveals Decrease in Neutralizing Capacity and Justifies Revised Qualifying Criteria for Coronavirus Disease 2019 Convalescent Plasma
RC Girardin, AP Dupuis, AF Payne, TJ Sullivan, D Strauss, MM Parker, KA McDonough |
The Journal of Infectious Diseases | 2021 |
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Markers of Polyfunctional SARS-CoV-2 Antibodies in Convalescent Plasma
H Natarajan, AR Crowley, SE Butler, S Xu, JA Weiner, EM Bloch, K Littlefield, W Wieland-Alter, RI Connor, PF Wright, SE Benner, TS Bonny, O Laeyendecker, D Sullivan, S Shoham, TC Quinn, HB Larman, A Casadevall, A Pekosz, AD Redd, AA Tobian, ME Ackerman, MS Diamond |
mBio | 2021 |
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In vivo characterization of emerging SARS-CoV-2 variant infectivity and human antibody escape potential
B Lam, YJ Kung, J Lin, SH Tseng, YC Tsai, L He, G Castiglione, E Egbert, EJ Duh, EM Bloch, AA Tobian, AM Milstone, RB Roden, TC Wu, CF Hung |
Cell Reports | 2021 |
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Lung Inflammation in Health and Disease, Volume II
YX Wang |
2021 | |
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Kinetics of Neutralizing Antibody Response Underscores Clinical COVID-19 Progression
Q Lei, H Hou, C Yu, Y Zhang, JL Ndzouboukou, X Lin, Z Yao, H Fu, Z Sun, F Wang, X Fan, B Xu |
Journal of Immunology Research | 2021 |
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Metabolic programs define dysfunctional immune responses in severe COVID-19 patients
EA Thompson, K Cascino, AA Ordonez, W Zhou, A Vaghasia, A Hamacher-Brady, NR Brady, IH Sun, R Wang, AZ Rosenberg, M Delannoy, R Rothman, K Fenstermacher, L Sauer, K Shaw-Saliba, EM Bloch, AD Redd, AA Tobian, M Horton, K Smith, A Pekosz, FR DAlessio, S Yegnasubramanian, H Ji, AL Cox, JD Powell |
Cell Reports | 2021 |
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Cellular and Humoral Immune Responses in Covid-19 and Immunotherapeutic Approaches
A Hasan, E Al-Ozairi, Z Al-Baqsumi, R Ahmad, F Al-Mulla |
ImmunoTargets and Therapy | 2021 |
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Sex-Related Differences in Drugs with Anti-Inflammatory Properties
A Farkouh, C Baumgärtel, R Gottardi, M Hemetsberger, M Czejka, A Kautzky-Willer |
Journal of Clinical Medicine | 2021 |
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Triple Jeopardy in Ageing: COVID-19, Co-morbidities and Inflamm-ageing
IM Rea, HD Alexander |
Ageing Research Reviews | 2021 |
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Convalescent Plasma for Infectious Diseases: Historical Framework and Use in COVID-19
JG Ripoll, N van Helmond, JW Senefeld, CC Wiggins, SA Klassen, SE Baker, KF Larson, BM Murphy, KJ Andersen, SK Ford, A Casadevall, MJ Joyner |
Clinical Microbiology Newsletter | 2021 |
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Immunology, immunopathogenesis and immunotherapeutics of COVID-19; an overview
LM Khosroshahi, M Rokni, T Mokhtari, F Noorbakhsh |
International Immunopharmacology | 2021 |
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Integrative overview of antibodies against SARS-CoV-2 and their possible applications in COVID-19 prophylaxis and treatment
NA Valdez-Cruz, E García-Hernández, C Espitia, L Cobos-Marín, C Altamirano, CG Bando-Campos, LF Cofas-Vargas, EW Coronado-Aceves, RA González-Hernández, P Hernández-Peralta, D Juárez-López, PA Ortega-Portilla, S Restrepo-Pineda, P Zelada-Cordero, MA Trujillo-Roldán |
Microbial cell factories | 2021 |
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Pregnancy alters interleukin-1 beta expression and antiviral antibody responses during severe acute respiratory syndrome coronavirus 2 infection
ML Sherer, J Lei, PS Creisher, M Jang, R Reddy, K Voegtline, S Olson, K Littlefield, HS Park, RL Ursin, A Ganesan, T Boyer, N Elsayed, DM Brown, SN Walch, AA Antar, YC Manabe, K Jones-Beatty, WC Golden, AJ Satin, JS Sheffield, A Pekosz, SL Klein, I Burd |
American Journal of Obstetrics and Gynecology | 2021 |
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Biological and Psychological Factors Determining Neuropsychiatric Outcomes in COVID-19
BN Tizenberg, LA Brenner, CA Lowry, OO Okusaga, DR Benavides, AJ Hoisington, ME Benros, JW Stiller, RC Kessler, TT Postolache |
Current Psychiatry Reports | 2021 |
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Type I Interferons in COVID-19 Pathogenesis
E Palermo, DD Carlo, M Sgarbanti, J Hiscott |
Biology : open access journal | 2021 |
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Distinct Features and Functions of Systemic and Mucosal Humoral Immunity Among SARS-CoV-2 Convalescent Individuals
SE Butler, AR Crowley, H Natarajan, S Xu, JA Weiner, CA Bobak, DE Mattox, J Lee, W Wieland-Alter, RI Connor, PF Wright, ME Ackerman |
Frontiers in immunology | 2021 |
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Sex Differences in Lung Imaging and SARS-CoV-2 Antibody Responses in a COVID-19 Golden Syrian Hamster Model
S Dhakal, CA Ruiz-Bedoya, R Zhou, PS Creisher, JS Villano, K Littlefield, JR Castillo, P Marinho, AE Jedlicka, AA Ordonez, M Bahr, N Majewska, MJ Betenbaugh, K Flavahan, AR Mueller, MM Looney, D Quijada, F Mota, SE Beck, J Brockhurst, AM Braxton, N Castell, M Stover, FR DAlessio, KA Pate, PC Karakousis, JL Mankowski, A Pekosz, SK Jain, SL Klein, CB Coyne |
mBio | 2021 |
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Functional convalescent plasma antibodies and pre-infusion titers shape the early severe COVID-19 immune response
JD Herman, C Wang, C Loos, H Yoon, J Rivera, ME Dieterle, D Haslwanter, RK Jangra, RH Bortz, KJ Bar, B Julg, K Chandran, D Lauffenburger, L Pirofski, G Alter |
Nature Communications | 2021 |
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The Journal of Clinical Investigation in the time of COVID-19
A Casadevall, S Jackson, GL Semenza, GF Tomaselli, RS Ahima |
Journal of Clinical Investigation | 2021 |
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Effect of time and titer in convalescent plasma therapy for COVID-19
P de Candia, F Prattichizzo, S Garavelli, RL Grotta, AD Rosa, A Pontarelli, R Parrella, A Ceriello, G Matarese |
iScience | 2021 |
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The Effect of Convalescent Plasma Therapy on Mortality Among Patients With COVID-19: Systematic Review and Meta-analysis
SA Klassen, JW Senefeld, PW Johnson, RE Carter, CC Wiggins, S Shoham, BJ Grossman, JP Henderson, J Musser, E Salazar, WR Hartman, NM Bouvier, ST Liu, L Pirofski, SE Baker, N van Helmond, RS Wright, DL Fairweather, KA Bruno, Z Wang, NS Paneth, A Casadevall, MJ Joyner |
Mayo Clinic Proceedings | 2021 |
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Convalescent Plasma for the Prevention and Treatment of COVID-19: A Systematic Review and Quantitative Analysis
HT Peng, SG Rhind, A Beckett |
2021 | |
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Mortality Benefit of Convalescent Plasma in COVID-19: A Systematic Review and Meta-Analysis
V Bansal, KS Mahapure, I Mehra, A Bhurwal, A Tekin, R Singh, I Gupta, SS Rathore, H Khan, S Deshpande, S Gulati, P Armaly, M Sheraton, R Kashyap |
Frontiers in Medicine | 2021 |
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Coronavirus Disease 2019 Convalescent Plasma and the Severe Acute Respiratory Syndrome Coronavirus 2 Neutralizing Titer
EM Bloch, EP Crowe, AA Tobian |
The Journal of Infectious Diseases | 2021 |
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ABO blood group and SARS‐CoV‐2 antibody response in a convalescent donor population
EM Bloch, EU Patel, C Marshall, K Littlefield, R Goel, BJ Grossman, JL Winters, R Shrestha, I Burgess, O Laeyendecker, S Shoham, D Sullivan, EA Gehrie, AD Redd, TC Quinn, A Casadevall, A Pekosz, AA Tobian |
Vox Sanguinis | 2021 |
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Comparative Performance of Five Commercially Available Serologic Assays To Detect Antibodies to SARS-CoV-2 and Identify Individuals with High Neutralizing Titers
EU Patel, EM Bloch, W Clarke, YH Hsieh, D Boon, Y Eby, RE Fernandez, OR Baker, M Keruly, CS Kirby, E Klock, K Littlefield, J Miller, HA Schmidt, P Sullivan, E Piwowar-Manning, R Shrestha, AD Redd, RE Rothman, D Sullivan, S Shoham, A Casadevall, TC Quinn, A Pekosz, AA Tobian, O Laeyendecker, MJ Loeffelholz |
Journal of clinical microbiology | 2021 |
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A Hemagglutination-Based Semiquantitative Test for Point-of-Care Determination of SARS-CoV-2 Antibody Levels
RL Kruse, Y Huang, A Lee, X Zhu, R Shrestha, O Laeyendecker, K Littlefield, A Pekosz, EM Bloch, AA Tobian, ZZ Wang, YW Tang |
Journal of clinical microbiology | 2021 |
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Kinetics of SARS-CoV-2 antibody responses pre-COVID-19 and post-COVID-19 convalescent plasma transfusion in patients with severe respiratory failure: an observational case–control study
MN Klein, EW Wang, P Zimand, H Beauchamp, C Donis, MD Ward, A Martinez-Hernandez, A Tabatabai, JW Baddley, EM Bloch, KE Mullins, MJ Fontaine |
Journal of clinical pathology | 2021 |
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COVID ‐19 convalescent plasma: Interim recommendations from the AABB
CS Cohn, L Estcourt, BJ Grossman, MB Pagano, ES Allen, EM Bloch, A Casadevall, DV Devine, NM Dunbar, F Foroutan, TJ Gniadek, R Goel, J Gorlin, MJ Joyner, RA Metcalf, JS Raval, TW Rice, BH Shaz, RR Vassallo, JL Winters, G Beaudoin, AA Tobian |
Transfusion | 2021 |
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Convalescent plasma for COVID‐19 — encouraging signals of efficacy
A Casadevall, AA Tobian |
British Journal of Haematology | 2021 |
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Evaluation of Serological SARS-CoV-2 Lateral Flow Assays for Rapid Point-of-Care Testing
SE Conklin, K Martin, YC Manabe, HA Schmidt, J Miller, M Keruly, E Klock, CS Kirby, OR Baker, RE Fernandez, YJ Eby, J Hardick, K Shaw-Saliba, RE Rothman, PP Caturegli, AD Redd, AA Tobian, EM Bloch, HB Larman, TC Quinn, W Clarke, O Laeyendecker, AJ McAdam |
Journal of clinical microbiology | 2021 |
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Corticosteroid treatment in COVID‐19 modulates host inflammatory responses and transcriptional signatures of immune dysregulation
AN Pinski, TL Steffen, MZ Zulu, SL George, A Dickson, D Tifrea, KJ Maroney, N Tedeschi, Y Zhang, RH Scheuermann, AK Pinto, JD Brien, I Messaoudi |
Journal of leukocyte biology | 2021 |
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Passive Immunity Should and Will Work for COVID-19 for Some Patients:
N Cimolai |
2021 | |
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The Principles of Antibody Therapy for Infectious Diseases with Relevance for COVID-19
A Casadevall, L Pirofski, MJ Joyner, DA Garsin |
mBio | 2021 |
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Administration of high titer convalescent anti-SARS-CoV-2 plasma: From donor selection to monitoring recipient outcomes
RP Mendoza, W Fyke, D Daniel, E Gabutan, B Das, H Bajaj, M Easy, A Vasileva, R Colbourn, M Alawad, A Dehghani, B Lin, D Emechebe, P Patel, A Jabbar, DB Nikolov, D Giovaniello, S Kang, L Tatem, K Bromberg, M Augenbraun, P Premsrirut, J Libien, AJ Norin |
Human Immunology | 2021 |
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Assessment of anti‐SARS‐CoV‐2 antibodies level in convalescents plasma
A Skorek, A JaźwińskaCuryłło, A Romanowicz, K Kwaśniewski, W Narożny, D Tretiakow |
Journal of Medical Virology | 2021 |
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Treating the endotheliopathy of SARS‐CoV ‐2 infection with plasma: Lessons learned from optimized trauma resuscitation with blood products
S Pati, E Fennern, JB Holcomb, M Barry, A Trivedi, AP Cap, MJ Martin, C Wade, R Kozar, JC Cardenas, JF Rappold, R Spiegel, MA Schreiber |
Transfusion | 2021 |
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Hospital-Based Donor Recruitment and Predonation Serologic Testing for COVID-19 Convalescent Plasma
J Balcerek, E Trejo, K Levine, P Couey, ZV Kornberg, C Rogine, C Young, PJ Li, BR Shy, JE Taylor, S Bakhtary, T Friedlander, KL Lynch, C Bern, JH Esensten |
American Journal of Clinical Pathology | 2021 |
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Aging in COVID-19: Vulnerability, immunity and intervention
Y Chen, SL Klein, BT Garibaldi, H Li, C Wu, NM Osevala, T Li, JB Margolick, G Pawelec, SX Leng |
Ageing Research Reviews | 2021 |
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Long-Term SARS-CoV-2 Specific Immunity Is Affected by the Severity of Initial COVID-19 and Patient Age
M Konik, M Lindemann, M Zettler, L Meller, S Dolff, V Rebmann, PA Horn, U Dittmer, A Krawczyk, L Schipper, M Trilling, OE Anastasiou, S Schwarzkopf, L Thümmler, C Taube, C Schöbel, T Brenner, EM Skoda, B Wilde, A Gäckler, O Witzke, H Rohn |
Journal of Clinical Medicine | 2021 |
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Durable Antibody Responses in Staff at Two Long-Term Care Facilities, during and Post SARS-CoV-2 Outbreaks
EN Gallichotte, M Nehring, MC Young, S Pugh, NR Sexton, E Fitzmeyer, KM Quicke, M Richardson, KL Pabilonia, N Ehrhart, BK Fosdick, S VandeWoude, GD Ebel, SW Long |
Microbiology spectrum | 2021 |
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Sex and age bias viral burden and interferon responses during SARS-CoV-2 infection in ferrets
ME Francis, B Richardson, U Goncin, M McNeil, M Rioux, MK Foley, A Ge, RD Pechous, J Kindrachuk, CM Cameron, C Richardson, J Lew, S Machtaler, MJ Cameron, V Gerdts, D Falzarano, AA Kelvin |
Scientific Reports | 2021 |
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Sex Disparities and Neutralizing-Antibody Durability to SARS-CoV-2 Infection in Convalescent Individuals
AJ Markmann, N Giallourou, DR Bhowmik, YJ Hou, A Lerner, DR Martinez, L Premkumar, H Root, D van Duin, S Napravnik, SD Graham, Q Guerra, R Raut, CJ Petropoulos, T Wrin, C Cornaby, J Schmitz, JA Kuruc, S Weiss, Y Park, R Baric, AM de Silva, DM Margolis, LA Bartelt, MF Pasetti |
mSphere | 2021 |
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Specific COVID-19 Symptoms Correlate with High Antibody Levels against SARS-CoV-2
MF Amjadi, SE OConnell, T Armbrust, AM Mergaert, SR Narpala, PJ Halfmann, SJ Bashar, CR Glover, AS Heffron, A Taylor, B Flach, DH OConnor, Y Kawaoka, AB McDermott, AK Sethi, MA Shelef |
ImmunoHorizons | 2021 |
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Disease Severity, Fever, Age, and Sex Correlate With SARS-CoV-2 Neutralizing Antibody Responses
S Schlickeiser, T Schwarz, S Steiner, K Wittke, NA Besher, O Meyer, U Kalus, A Pruß, F Kurth, T Zoller, M Witzenrath, LE Sander, MA Müller, C Scheibenbogen, HD Volk, C Drosten, VM Corman, LG Hanitsch |
Frontiers in immunology | 2021 |
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Neutralizing antibody responses over time in demographically and clinically diverse individuals recovered from SARS-CoV-2 infection in the United States and Peru: A cohort study
S Karuna, SS Li, S Grant, SR Walsh, I Frank, M Casapia, M Trahey, O Hyrien, L Fisher, MD Miner, AK Randhawa, L Polakowski, JG Kublin, L Corey, D Montefiori, JG Beeson |
PLoS Medicine | 2021 |
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Presence and short‐term persistence of SARS‐CoV ‐2 neutralizing antibodies in COVID ‐19 convalescent plasma donors
K Annen, TE Morrison, MG DomBourian, MK McCarthy, L Huey, PA Merkel, G Andersen, E Schwartz, V Knight |
Transfusion | 2021 |
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Seroconversion and Abundance of IgG Antibodies against S1-RBD of SARS-CoV-2 and Neutralizing Activity in the Chilean Population
R González-Stegmaier, K Cereceda, JL Briones, C Beltran-Pávez, A Oyarzún-Arrau, S Riquelme-Barrios, C Selman, F Yarad, M Mahave, C Caglevic, R Morales, A Aguirre, F Valiente-Echeverría, R Soto-Rifo, H Marsiglia, R Gazitua, F Villarroel-Espindola, B Xu |
Journal of Immunology Research | 2021 |
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Clinical predictors of SARS‐CoV‐2 neutralizing antibody titers in COVID‐19 convalescents: Implications for convalescent plasma donor recruitment
D Focosi, M Franchini |
European Journal of Haematology | 2021 |
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124I-Iodo-DPA-713 Positron Emission Tomography in a Hamster Model of SARS-CoV-2 Infection
CA Ruiz-Bedoya, F Mota, AA Ordonez, CA Foss, AK Singh, M Praharaj, FJ Mahmud, A Ghayoor, K Flavahan, PD Jesus, M Bahr, S Dhakal, R Zhou, CV Solis, KR Mulka, WR Bishai, A Pekosz, JL Mankowski, J Villano, SL Klein, SK Jain |
Molecular Imaging and Biology | 2021 |
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Comparative performance of multiplex salivary and commercially available serologic assays to detect SARS-CoV-2 IgG and neutralization titers
CD Heaney, N Pisanic, PR Randad, K Kruczynski, T Howard, X Zhu, K Littlefield, EU Patel, R Shrestha, O Laeyendecker, S Shoham, D Sullivan, K Gebo, D Hanley, AD Redd, TC Quinn, A Casadevall, JM Zenilman, A Pekosz, EM Bloch, AA Tobian |
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology | 2021 |
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Emergency seed funding for COVID-19 research: lessons from Johns Hopkins University
J Messersmith, C Stoddart-Osumah, M Lennon, D Wirtz |
Journal of Clinical Investigation | 2021 |
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Long-Term Persistence and Relevant Therapeutic Impact of High-Titer Viral-Neutralizing Antibody in a Convalescent COVID-19 Plasma Super-Donor: A Case Report
MD Rienzo, ML Foddai, L Conti, C Mandoj, S Iaboni, I Saladini, C Castilletti, G Matusali, DR Donno, L Marchioni, S Ianniello, A Corpolongo, M Palange, G Ciliberto, G Piaggio, FD Marco |
Frontiers in immunology | 2021 |
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Sex Differences in Immunity to Viral Infections
H Jacobsen, SL Klein |
Frontiers in immunology | 2021 |
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SARS‐CoV‐2‐specific humoral and cellular immunity persists through 9 months irrespective of COVID‐19 severity at hospitalisation
JT Sandberg, R Varnaitė, W Christ, P Chen, JR Muvva, KT Maleki, M García, M Dzidic, E Folkesson, M Skagerberg, G Ahlén, L Frelin, M Sällberg, LI Eriksson, O Rooyackers, A Sönnerborg, M Buggert, NK Björkström, S Aleman, K Strålin, J Klingström, HG Ljunggren, K Blom, S GredmarkRuss, M Akber, S Aleman, L Berglin, H Bergsten, NK Björkström, S Brighenti, D Brownlie, M Butrym, BJ Chambers, M Cornillet, A Cuapio, ID Lozano, L Dillner, J Emgård, M FlodströmTullberg, A Färnert, Y Gao, H Glans, JB Gorin, J Grip, A HarounIzquierdo, E Henriksson, L Hertwig, S Kalsum, T Kammann, E Kokkinou, E Kvedaraite, MG Loreti, M Lourda, KJ Malmberg, N Marquardt, C Maucourant, J Mårtensson, J Michaëlsson, J Mjösberg, K Moll, P Nauclér, A NorrbyTeglund, LM Medina, T Parrot, A PerezPotti, BP Persson, L Radler, E Ringqvist, O RiveraBallesteros, JK Sandberg, T Sekine, E Sohlberg, T Soini, M Svensson, J Tynell, C Unge, A von Kries, D Wullimann |
IBMS BoneKEy | 2021 |
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The Fc-mediated effector functions of a potent SARS-CoV-2 neutralizing antibody, SC31, isolated from an early convalescent COVID-19 patient, are essential for the optimal therapeutic efficacy of the antibody
CE Chan, SG Seah, DH Chye, S Massey, M Torres, AP Lim, SK Wong, JJ Neo, PS Wong, JH Lim, GS Loh, D Wang, JD Boyd-Kirkup, S Guan, D Thakkar, GH Teo, K Purushotorman, PE Hutchinson, BE Young, JG Low, PA MacAry, H Hentze, VS Prativadibhayankara, K Ethirajulu, JE Comer, CT Tseng, AD Barrett, PJ Ingram, T Brasel, BJ Hanson, K Harrod |
PloS one | 2021 |
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Engineering luminescent biosensors for point-of-care SARS-CoV-2 antibody detection
SK Elledge, XX Zhou, JR Byrnes, AJ Martinko, I Lui, K Pance, SA Lim, JE Glasgow, AA Glasgow, K Turcios, NS Iyer, L Torres, MJ Peluso, TJ Henrich, TT Wang, CM Tato, KK Leung, B Greenhouse, JA Wells |
Nature Biotechnology | 2021 |
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The Characterization of Disease Severity Associated IgG Subclasses Response in COVID-19 Patients
H Luo, T Jia, J Chen, S Zeng, Z Qiu, S Wu, X Li, Y Lei, X Wang, W Wu, R Zhang, X Zou, T Feng, R Ding, Y Zhang, YQ Chen, C Sun, T Wang, S Fang, Y Shu |
Frontiers in immunology | 2021 |
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Sex and Gender Differences in Testing, Hospital Admission, Clinical Presentation, and Drivers of Severe Outcomes From COVID-19
EP Scully, G Schumock, M Fu, G Massaccesi, J Muschelli, J Betz, EY Klein, NE West, M Robinson, BT Garibaldi, K Bandeen-Roche, S Zeger, SL Klein, A Gupta |
Open Forum Infectious Diseases | 2021 |
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SARS-CoV-2 neutralizing antibodies: Longevity, breadth, and evasion by emerging viral variants
F Tea, AO Stella, A Aggarwal, DR Darley, D Pilli, D Vitale, V Merheb, FX Lee, P Cunningham, GJ Walker, C Fichter, DA Brown, WD Rawlinson, SR Isaacs, V Mathivanan, M Hoffmann, S Pöhlman, O Mazigi, D Christ, DE Dwyer, RJ Rockett, V Sintchenko, VC Hoad, DO Irving, GJ Dore, IB Gosbell, AD Kelleher, GV Matthews, F Brilot, SG Turville |
PLoS Medicine | 2021 |
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A newly identified linear epitope on non-RBD region of SARS-CoV-2 spike protein improves the serological detection rate of COVID-19 patients
Y Zhang, Z Yang, S Tian, B Li, T Feng, J He, M Jiang, X Tang, S Mei, H Li, Y Zhong, G Li, M Tang, S Liu, T Tang, C Wang, X Wang |
BMC Microbiology | 2021 |
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CD8+ T-Cell Responses in COVID-19 Convalescent Individuals Target Conserved Epitopes From Multiple Prominent SARS-CoV-2 Circulating Variants
AD Redd, A Nardin, H Kared, EM Bloch, A Pekosz, O Laeyendecker, B Abel, M Fehlings, TC Quinn, AA Tobian |
Open Forum Infectious Diseases | 2021 |
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Diverse Humoral Immune Responses in Younger and Older Adult COVID-19 Patients
JM Sasson, JJ Campo, RM Carpenter, MK Young, AZ Randall, K Trappl-Kimmons, A Oberai, C Hung, J Edgar, AA Teng, JV Pablo, X Liang, A Yee, WA Petri, D Camerini, PJ Johnson |
mBio | 2021 |
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SARS-CoV-2 B.1.1.7 (alpha) and B.1.351 (beta) variants induce pathogenic patterns in K18-hACE2 transgenic mice distinct from early strains
P Radvak, HJ Kwon, M Kosikova, U Ortega-Rodriguez, R Xiang, JN Phue, RF Shen, J Rozzelle, N Kapoor, T Rabara, J Fairman, H Xie |
Nature Communications | 2021 |
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Biology of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the humoral immunoresponse: A systematic review of evidence to support global policy-level actions and research
S Nair, X Chen |
2021 | |
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Seroprevalence of SARS-CoV-2 (COVID-19) exposure in pet cats and dogs in Minnesota, USA
M Dileepan, D Di, Q Huang, S Ahmed, D Heinrich, H Ly, Y Liang |
Virulence | 2021 |
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Characteristics of coronavirus disease 19 convalescent plasma donors and donations in the New York metropolitan area
S Jain, K Garg, SM Tran, IL Rask, M Tarczon, V Nandi, DA Kessler, D Strauss, BS Sachais, K Yazdanbakhsh, S Rehmani, L Luchsinger, PA Shi |
Transfusion | 2021 |
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Household level SARS-CoV-2 sero-epidemiology in a high prevalence group of adults and children-implications for community infection control
A Werzberger, JM Carreño, SS Team, A Polinger, F Krammer, P Zachariah |
American journal of infection control | 2021 |
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COVID ‐19 convalescent plasma; time for “goal directed therapy”?
CM Knudson, JB Jackson |
Transfusion | 2021 |
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Association of HLA genotypes, AB0 blood type and chemokine receptor 5 mutant CD195 with the clinical course of COVID-19
JC Fischer, AG Schmidt, E Bölke, M Uhrberg, V Keitel, T Feldt, B Jensen, D Häussinger, O Adams, EM Schneider, V Balz, J Enczmann, J Rox, D Hermsen, K Schulze-Bosse, D Kindgen-Milles, WT Knoefel, M van Griensven, J Haussmann, B Tamaskovics, C Plettenberg, K Scheckenbach, S Corradini, A Pedoto, K Maas, L Schmidt, O Grebe, I Esposito, A Ehrhardt, M Peiper, BA Buhren, C Calles, A Stöhr, A Lichtenberg, NF Freise, M Lutterbeck, A Rezazadeh, W Budach, C Matuschek |
European Journal of Medical Research | 2021 |
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Next-Generation Serology by Mass Spectrometry: Readout of the SARS-CoV-2 Antibody Repertoire
RD Melani, BJ Soye, JO Kafader, E Forte, M Hollas, V Blagojevic, F Negrão, JP McGee, B Drown, C Lloyd-Jones, HS Seckler, JM Camarillo, PD Compton, RD LeDuc, B Early, RT Fellers, BK Cho, BB Mattamana, YA Goo, PM Thomas, MK Ash, PP Bhimalli, L Al-Harthi, BE Sha, JR Schneider, NL Kelleher |
Journal of Proteome Research | 2021 |
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Rapid and Flexible Platform To Assess Anti-SARS-CoV-2 Antibody Neutralization and Spike Protein-Specific Antivirals
D Stelitano, SP Weisberg, MP Goldklang, Y Zhu, FT Bovier, GF Kalantarov, G Greco, D Decimo, G Franci, M Cennamo, G Portella, M Galdiero, C Mathieu, B Horvat, IN Trakht, A Moscona, MA Whitt, M Porotto, R Dutch |
mSphere | 2021 |
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SARS-CoV-2 antibody kinetics eight months from COVID-19 onset: Persistence of spike antibodies but loss of neutralizing antibodies in 24% of convalescent plasma donors
E Terpos, D Stellas, M Rosati, TN Sergentanis, X Hu, M Politou, V Pappa, I Ntanasis-Stathopoulos, S Karaliota, J Bear, D Donohue, M Pagoni, E Grouzi, E Korompoki, GN Pavlakis, BK Felber, MA Dimopoulos |
European Journal of Internal Medicine | 2021 |
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Detection and predictors of anti-SARS-CoV-2 antibody levels in COVID-19 patients at 8 months after symptom onset
J Guo, L Li, Q Wu, H Li, Y Li, X Hou, F Yang, Z Qin |
Future Virology | 2021 |
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Centenarians and extremely old people living with frailty can elicit durable SARS-CoV-2 spike specific IgG antibodies with virus neutralization functions following virus infection as determined by serological study
MK Foley, SD Searle, A Toloue, R Booth, A Falkenham, D Falzarano, S Rubino, ME Francis, M McNeil, C Richardson, J LeBlanc, S Oldford, V Gerdts, MK Andrew, SA McNeil, B Clarke, K Rockwood, DJ Kelvin, AA Kelvin |
2021 | |
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Colloidal gold immunochromatographic assay (GICA) is an effective screening method for identifying detectable anti-SARS-CoV-2 neutralizing antibodies
X Li, Y Yin, L Pang, S Xu, F Lu, D Xu, T Shen |
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases | 2021 |
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Clinical correlates of anti-SARS-CoV-2 antibody profiles in Spanish COVID-19 patients from a high incidence region
R Markewitz, A Torge, KP Wandinger, D Pauli, A Franke, L Bujanda, JM Marimón, JM Banales, MA Gutierrez-Stampa, B Nafría, R Junker |
Scientific Reports | 2021 |
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Deep dissection of the antiviral immune profile of patients with COVID-19
D Atanackovic, SV Avila, F Lutfi, D de Miguel-Perez, X Fan, G Sanchez-Petitto, EV Mause, J Siglin, J Baddley, HD Mannuel, H Alkhaldi, KG Hankey, R Lapidus, M Kleinberg, J Rabin, C Shanholtz, C Rolfo, AP Rapoport, S Dahiya, T Luetkens |
2021 | |
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Longitudinal SARS-CoV-2 Seroconversion Course and Antibody Levels by Blood Groups in Convalescent Plasma Donors in Turkey
A Karaca, MN Günçıkan, NN Sözmen, GG Karadağ, M Yılmaz |
2021 | |
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Evaluation of COVID-19 antibody response with using three different tests
Ö Appak, A Gülmez, I Güzel, NS Gezer, ÖG Doruk, OA Ergor, N Esen, AA Sayıner |
Iranian Journal of Microbiology | 2021 |
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SARS-CoV-2 Antibodies in Hemodialysis Patients Six Months after Infection Compared to Healthcare Workers
H Boulanger, SA Saksi, J Achiche, F Batusanski, N Stawiarski, A Diddaoui, L Fromentin, M Chawki, A Scholze |
International Journal of Nephrology | 2021 |
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Mental Health and Substance Use Associated with Hospitalization among People with COVID-19: A Population-Based Cohort Study
HA García, J Wilton, K Smolina, M Chong, D Rasali, M Otterstatter, C Rose, N Prystajecky, S David, E Galanis, G McKee, M Krajden, NZ Janjua |
Viruses | 2021 |
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12-month SARS-CoV-2 antibody persistency in a Tyrolean COVID-19 cohort
F Deisenhammer, A Bauer, C Kavelar, D Rudzki, A Rössler, J Kimpel, W Borena, M Reindl |
Wiener klinische Wochenschrift | 2021 |
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Case Report: Serial Cases: Prolongation of High Immunoglobulin G Level in Repetitive COVID-19 Convalescence Plasma Donor in Saiful Anwar Hospital Malang, Indonesia
N Nurarifah, HP Brahmantyo, SO Wardhani, DH Hermanto, PM Arsana |
Frontiers in immunology | 2021 |
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The demographic and serological characteristics of COVID-19 convalescent plasma donors: Identification of basic criteria for optimal donor selection
A Fazeli, S Sharifi, S Mohammadi, M Bahraini, A Arabkhazaeli, N Jelveh, P Eshghi |
Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis | 2021 |
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Sandwich/competitive immuno-sensors on micro-interface for SARS-CoV-2 neutralizing antibodies
Q Lin, J Wu, L Liu, W Wu, X Fang, J Kong |
Analytica Chimica Acta | 2021 |
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Association between Reactogenicity and Immunogenicity after Vaccination with BNT162b2
S Bauernfeind, B Salzberger, F Hitzenbichler, K Scigala, S Einhauser, R Wagner, A Gessner, J Koestler, D Peterhoff |
Human vaccines | 2021 |
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Serum IgG anti-SARS-CoV-2 Binding Antibody Level Is Strongly Associated With IgA and Functional Antibody Levels in Adults Infected With SARS-CoV-2
X Ye, LS Angelo, EG Nicholson, OP Iwuchukwu, WC de Rezende, A Rajan, LO Aideyan, TJ McBride, N Bond, P Santarcangelo, YJ Rayford, L Ferlic-Stark, S Fragoso, Z Momin, H Liu, K Truong, B Lopez, ME Conner, AP Rice, JT Kimata, V Avadhanula, PA Piedra |
Frontiers in immunology | 2021 |
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Hospitalised versus outpatient COVID‐19 patients' background characteristics and comorbidities: A systematic review and meta‐analysis
PP MatteyMora, CA Begle, CK Owusu, C Chen, MA Parker |
Reviews in Medical Virology | 2021 |
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Hamsters as a Model of Severe Acute Respiratory Syndrome Coronavirus-2
AM Braxton, PS Creisher, CA Ruiz-Bedoya, KR Mulka, S Dhakal, AA Ordonez, SE Beck, SK Jain, JS Villano |
Comparative medicine | 2021 |
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Dynamics of IgG-avidity and antibody levels after Covid-19
E Löfström, A Eringfält, A Kötz, F Wickbom, J Tham, M Lingman, JM Nygren, J Undén |
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology | 2021 |
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Kidney transplant recipients vaccinated before transplantation maintain superior humoral response to SARS‐CoV‐2 vaccine
A Grupper, E Katchman, M BenYehoyada, L Rabinowich, D Schwartz, IF Schwartz, M Shashar, T Halperin, D Turner, Y Goykhman, O Shibolet, S Levy, I Houri, R Baruch, H Katchman |
Clinical Transplantation | 2021 |
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Serological and viral genetic features of patients with COVID-19 in a selected German patient cohort—correlation with disease characteristics
J Schmidt, S Berghaus, F Blessing, F Wenzel, H Herbeck, J Blessing, P Schierack, S Rödiger, D Roggenbuck |
GeroScience | 2021 |
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SARS-CoV-2 messenger RNA vaccine antibody response and reactogenicity in heart and lung transplant recipients
AM Hallett, RS Greenberg, BJ Boyarsky, PD Shah, MT Ou, AT Teles, MR Krach, JI López, WA Werbel, RK Avery, S Bae, AA Tobian, AB Massie, RS Higgins, JM Garonzik-Wang, DL Segev, EL Bush |
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation | 2021 |
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Analysis of antibody responses after COVID-19 vaccination in liver transplant recipients and those with chronic liver diseases
PJ Thuluvath, P Robarts, M Chauhan |
Journal of Hepatology | 2021 |
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Systematic profiling of SARS-CoV-2-specific IgG responses elicited by an inactivated virus vaccine identifies peptides and proteins for predicting vaccination efficacy
ML Ma, DW Shi, Y Li, W Hong, DY Lai, JB Xue, HW Jiang, HN Zhang, H Qi, QF Meng, SJ Guo, DJ Xia, JJ Hu, S Liu, HY Li, J Zhou, W Wang, X Yang, XL Fan, Q Lei, WJ Chen, CS Li, XM Yang, SH Xu, HP Wei, SC Tao |
Cell Discovery | 2021 |
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Prevalence of SARS-CoV-2 IgG antibodies and their association with clinical symptoms of COVID-19 in Estonia (KoroSero-EST-1 study)
P Jõgi, H Soeorg, D Ingerainen, M Soots, F Lättekivi, P Naaber, K Toompere, P Peterson, L Haljasmägi, E Žusinaite, H Vaas, M Pauskar, A Shablinskaja, K Kaarna, H Paluste, K Kisand, M Oona, R Janno, I Lutsar |
Vaccine | 2021 |
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Vaccination versus infection with SARS‐CoV‐2: Establishment of a high avidity IgG response versus incomplete avidity maturation
F Struck, P Schreiner, E Staschik, K WochinzRichter, S Schulz, E Soutschek, M Motz, G Bauer |
Journal of Medical Virology | 2021 |
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Seroconversion among COVID-19 patients admitted in a dedicated COVID hospital: A longitudinal prospective study of 1000 patients
AK Yadav, S Ghosh, A Kotwal, SK Kaushik, S Bobdey, R Sahu, S Kapoor, DS Faujdar, PT Teli, V Anand |
Medical Journal Armed Forces India | 2021 |
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Predicting the efficacy of COVID-19 convalescent plasma donor units with the Lumit Dx anti-receptor binding domain assay
SK Janaka, NM Clark, DT Evans, H Mou, M Farzan, JP Connor, PL Ho |
PloS one | 2021 |
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Prevalence of neutralising antibodies against SARS-CoV-2 in acute infection and convalescence: A systematic review and meta-analysis
HR Savage, VS Santos, T Edwards, E Giorgi, S Krishna, TD Planche, HM Staines, JR Fitchett, DE Kirwan, AI Atienzar, DJ Clark, ER Adams, LE Cuevas, T Lin |
PLoS neglected tropical diseases | 2021 |
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Sex-based clinical and immunological differences in COVID-19
B Huang, Y Cai, N Li, K Li, Z Wang, L Li, L Wu, M Zhu, J Li, Z Wang, M Wu, W Li, W Wu, L Zhang, X Xia, S Wang, H Chen, Q Wang |
BMC Infectious Diseases | 2021 |
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Assessment of serological assays for identifying high titer convalescent plasma
CW Farnsworth, JB Case, K Hock, RE Chen, JA O'Halloran, R Presti, CW Goss, AM Rauseo, A Ellebedy, ES Theel, MS Diamond, JP Henderson |
Transfusion | 2021 |
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Understanding COVID-19 Epidemiology and Implications for Control: The Experience from a Greek Semi-Closed Community
OS Kotsiou, D Papagiannis, EC Fradelos, G Perlepe, A Miziou, DS Siachpazidou, KI Gourgoulianis |
Journal of Clinical Medicine | 2021 |
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Neutralizing Antibody Responses to SARS-CoV-2 in Korean Patients Who Have Recovered from COVID-19
YJ Kim, JY Bae, S Bae, S Hwang, KT Kwon, HH Chang, WK Lee, C Cui, GE Lee, SW Kim, MS Park |
Yonsei Medical Journal | 2021 |
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Prevalence of Low Level of Vitamin D Among COVID-19 Patients and Associated Risk Factors in India – A Hospital-Based Study
S Singh, N Nimavat, AK Singh, S Ahmad, N Sinha |
International journal of general medicine | 2021 |
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Predictive factors of smell recovery in a clinical series of 288 coronavirus disease 2019 patients with olfactory dysfunction
S Saussez, S Sharma, A Thiriard, V Olislagers, IV Duc, SD Bon, M Khalife, S Hans, GD Riu, C Hopkins, JR Lechien, LA Vaira, A Marchant |
European journal of neurology : the official journal of the European Federation of Neurological Societies | 2021 |
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COVID-19: Structural Considerations for Virus Pathogenesis, Therapeutic Strategies and Vaccine Design in the Novel SARS-CoV-2 Variants Era
E Volkan |
Molecular Biotechnology | 2021 |
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SARS-CoV-2 serology in 4000 health care and administrative staff across seven sites in Lombardy, Italy
MT Sandri, E Azzolini, V Torri, S Carloni, C Pozzi, M Salvatici, M Tedeschi, M Castoldi, A Mantovani, M Rescigno |
Scientific Reports | 2021 |
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Delayed Rise of Oral Fluid Antibodies, Elevated BMI, and Absence of Early Fever Correlate With Longer Time to SARS-CoV-2 RNA Clearance in a Longitudinally Sampled Cohort of COVID-19 Outpatients
AA Antar, T Yu, N Pisanic, R Azamfirei, JA Tornheim, DM Brown, K Kruczynski, JP Hardick, T Sewell, M Jang, T Church, SN Walch, C Reuland, VS Bachu, K Littlefield, HS Park, RL Ursin, A Ganesan, O Kusemiju, B Barnaba, C Charles, M Prizzi, JR Johnstone, C Payton, W Dai, J Fuchs, G Massaccesi, DT Armstrong, JL Townsend, SC Keller, ZO Demko, C Hu, MC Wang, LM Sauer, HH Mostafa, JC Keruly, SH Mehta, SL Klein, AL Cox, A Pekosz, CD Heaney, DL Thomas, PW Blair, YC Manabe |
Open Forum Infectious Diseases | 2021 |
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Demographic and clinical correlates of acute and convalescent SARS-CoV-2 infection among patients of a U.S. emergency department
O Laeyendecker, YH Hsieh, RE Rothman, G Dashler, T Kickler, RE Fernandez, W Clarke, EU Patel, AA Tobian, GD Kelen, TC Quinn, HA Schmidt, J Miller, M Keruly, E Klock, CS Kirby, OR Baker, R Wang, IV Lake, M Youbi, S Reineck, M Khan, R Knaub, E Ricketts, YJ Eby, D Anderson, J Hurley |
The American Journal of Emergency Medicine | 2021 |
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The predictors of high titer of anti-SARS-CoV-2 antibody of convalescent plasma donors
SO Wardhani, JK Fajar, N Nurarifah, DH Hermanto, S Fatonah, S Djajalaksana, AZ Fatoni, PM Arsana, L Wulandari, G Soegiarto, K Dhama, H Harapan |
Clinical Epidemiology and Global Health | 2021 |
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Dynamics of anti-SARS-CoV-2 IgG antibodies post-COVID-19 in a Brazilian Amazon population
CD Bichara, E da Silva Graça Amoras, GL Vaz, MK da Silva Torres, MA Queiroz, IP do Amaral, IM Vallinoto, CN Bichara, AC Vallinoto |
BMC Infectious Diseases | 2021 |
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Antibody Response to 2-Dose SARS-CoV-2 mRNA Vaccine Series in Solid Organ Transplant Recipients
BJ Boyarsky, WA Werbel, RK Avery, AA Tobian, AB Massie, DL Segev, JM Garonzik-Wang |
Journal of the American Medical Association | 2021 |
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Antibody Responses in COVID-19: A Review
M Chvatal-Medina, Y Mendez-Cortina, PJ Patiño, PA Velilla, MT Rugeles |
Frontiers in immunology | 2021 |
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Correlates of Neutralization against SARS-CoV-2 Variants of Concern by Early Pandemic Sera
SJ Vidal, AY Collier, J Yu, K McMahan, LH Tostanoski, JD Ventura, M Aid, L Peter, C Jacob-Dolan, T Anioke, A Chang, H Wan, R Aguayo, D Ngo, RE Gerszten, MS Seaman, DH Barouch, JK Pfeiffer |
Journal of virology | 2021 |
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Reduced humoral response to mRNA SARS‐CoV‐2 BNT162b2 vaccine in kidney transplant recipients without prior exposure to the virus
A Grupper, L Rabinowich, D Schwartz, IF Schwartz, M BenYehoyada, M Shashar, E Katchman, T Halperin, D Turner, Y Goykhman, O Shibolet, S Levy, I Houri, R Baruch, H Katchman |
American Journal of Transplantation | 2021 |
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Sex-biased clinical presentation and outcomes from COVID-19
EP Scully, A Gupta, SL Klein |
Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases | 2021 |
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Associating SARS-CoV-2 Serological Assays with Protection: Where the Field Stands
MS Tang, CW Farnsworth |
Clinical chemistry | 2021 |
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Correlation of Automated Chemiluminescent Method with Enzyme-Linked Immunosorbent Assay (ELISA) Antibody Titers in Convalescent COVID-19 Plasma Samples: Development of Rapid, Cost-Effective Semi-Quantitative Diagnostic Methods
R Mendoza, M Silver, A Zuretti, M Christian, B Das, A Norin, P Borgen, J Libien, M Bluth |
Journal of blood medicine | 2021 |
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Validation and performance comparison of two SARS-CoV-2 IgG/IgM rapid tests
NN Awaji, HT Ahmedah, IM Alsaady, RA Bawaked, MA Alraey, AA Alasiri, AM Alfaifi, HA Alshehri, R Alserihi, EB Yasin |
Saudi Journal of Biological Sciences | 2021 |
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Immunogenicity of a Single Dose of SARS-CoV-2 Messenger RNA Vaccine in Solid Organ Transplant Recipients
BJ Boyarsky, WA Werbel, RK Avery, AA Tobian, AB Massie, DL Segev, JM Garonzik-Wang |
Journal of the American Medical Association | 2021 |
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The potential significance of high avidity immunoglobulin G (IgG) for protective immunity towards SARS-CoV-2
G Bauer |
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases | 2021 |
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Auto-antibodies against type I IFNs are associated with severe COVID-19 pneumonia
W Zhou, W Wang |
Signal Transduction and Targeted Therapy | 2021 |
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The Physiological Mechanisms of the Sex-Based Difference in Outcomes of COVID19 Infection
S Wray, S Arrowsmith |
Frontiers in physiology | 2021 |
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Early Development and Durability of SARS-CoV-2 Antibodies Among Solid Organ Transplant Recipients: A Pilot Study
BJ Boyarsky, MT Ou, WA Werbel, RK Avery, WA Clarke, AA Tobian, AB Massie, DL Segev, JM Wang |
Transplantation | 2021 |
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The “false-positive” conundrum: IgA reference level overestimates the seroprevalence of antibodies to SARS-CoV-2
B Caramelli, MC Escalante-Rojas, HK Chauhan, RF Siciliano, MS Bittencourt, AC Micelli |
Journal of Global Health | 2021 |
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Laboratory evaluation of SARS-CoV-2 in the COVID-19 pandemic
BA Parikh, CW Farnsworth |
Best practice & research. Clinical rheumatology | 2021 |
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SARS-CoV-2 Infection Severity Is Linked to Superior Humoral Immunity against the Spike
JJ Guthmiller, O Stovicek, J Wang, S Changrob, L Li, P Halfmann, NY Zheng, H Utset, CT Stamper, HL Dugan, WD Miller, M Huang, YN Dai, CA Nelson, PD Hall, M Jansen, K Shanmugarajah, JS Donington, F Krammer, DH Fremont, A Joachimiak, Y Kawaoka, V Tesic, ML Madariaga, PC Wilson, S Schultz-Cherry |
mBio | 2021 |
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Orthogonal immunoassays for IgG antibodies to SARS-CoV-2 antigens reveal that immune response lasts beyond 4 mo post illness onset
V Sasisekharan, N Pentakota, A Jayaraman, K Tharakaraman, GN Wogan, U Narayanasami |
Proceedings of the National Academy of Sciences | 2021 |
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Comparison of SARS-CoV-2 IgM and IgG seroconversion profiles among hospitalized patients in two US cities
EP Orner, MA Rodgers, K Hock, MS Tang, R Taylor, M Gardiner, A Olivo, A Fox, J Prostko, G Cloherty, CW Farnsworth |
Diagnostic Microbiology and Infectious Disease | 2021 |
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Prevalence of SARS-CoV-2 IgG antibodies in a large prospective cohort study of elite football players in Germany (May–June 2020): implications for a testing protocol in asymptomatic individuals and estimation of the rate of undetected cases
D Mack, BC Gärtner, A Rössler, J Kimpel, K Donde, O Harzer, W Krutsch, D von Laer, T Meyer |
Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases | 2021 |
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Hidden in plain sight: sex and gender in global pandemics
EP Scully |
Current Opinion in HIV and AIDS | 2021 |
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Antibodies, Immunity, and COVID-19
B Spellberg, TB Nielsen, A Casadevall |
JAMA internal medicine | 2021 |
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Role of Senescence and Aging in SARS-CoV-2 Infection and COVID-19 Disease
SM Lynch, G Guo, DS Gibson, AJ Bjourson, TS Rai |
Cells | 2021 |
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Demographic and Clinical Factors Associated with Reactivity of Anti-SARS-CoV-2 Antibodies in Serbian Convalescent Plasma Donors
J Grujić, N Bujandrić, Z Budakov-Obradović, V Dolinaj, D Bogdan, N Savić, A Cabezas-Cruz, D Mijatović, V Simin, N Anđelić, P Banović |
International journal of environmental research and public health | 2021 |
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Antibody levels remain high to one-year’s follow-up after moderate and severe COVID-19, but not after mild cases
A Kallaste, K Kisand, A Aart, K Kisand, P Peterson, M Lember |
Infectious Diseases | 2021 |
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The challenge of avidity determination in SARS‐CoV‐2 serology
Bauer G, Struck F, Schreiner P, Staschik E, Soutschek E, Motz M |
Journal of Medical Virology | 2021 |
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COVID-19 convalescent plasma
Tobian AA, Cohn CS, Shaz BH |
Blood | 2021 |
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Second round statewide sentinel-based population survey for estimation of the burden of active infection and anti-SARS-CoV-2 IgG antibodies in the general population of Karnataka, India, during January-February 2021
Padma MR, Dinesh P, Sundaresan R, Athreya S, Shiju S, Maroor PS, Hande RL, Akhtar J, Chandra T, Ravi D, Lobo E, Ana Y, Shriyan P, Desai A, Rangaiah A, Munivenkatappa A, Krishna S, Basawarajappa SG, Sreedhara H, Siddesh K, Amrutha Kumari B, Umar N, Mythri B, Mythri K, Sudarshan MK, Vasanthapuram R, Babu GR |
2021 | |
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Polyclonal hyper immunoglobulin: A proven treatment and prophylaxis platform for passive immunization to address existing and emerging diseases
Tharmalingam T, Han X, Wozniak A, Saward L |
Human Vaccines & Immunotherapeutics | 2021 |
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Persistence of immunoglobulin G after natural infection with SARS‐CoV‐2
Kreuzberger N, Hirsch C, Vanshylla K, Di Cristanziano V, Dorando E, Khosravi Z, Neidhardt M, Salomon S, Monsef I, Lange B, Skoetz N |
The Cochrane Database of Systematic Reviews | 2021 |
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Research and resource needs for understanding host immune responses to SARS-CoV-2 and COVID-19 vaccines during aging
PrabhuDas M, Fuldner R, Farber D, Kuchel GA, Mannick J, Nikolich-Zugich J, Sen R, Turner J |
2021 | |
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Antibody Attributes that Predict the Neutralization and Effector Function of Polyclonal Responses to SARS-CoV-2.
Natarajan H, Xu S, Crowley AR, Butler SE, Weiner JA, Bloch EM, Littlefield K, Benner SE, Shrestha R, Ajayi O, Wieland-Alter W, Sullivan D, Shoham S, Quinn TC, Casadevall A, Pekosz A, Redd AD, Tobian AAR, Connor RI, Wright PF, Ackerman ME |
medRxiv : the preprint server for health sciences | 2021 |
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Boosting of Cross-Reactive Antibodies to Endemic Coronaviruses by SARS-CoV-2 Infection but not Vaccination with Stabilized Spike.
Crowley AR, Natarajan H, Hederman AP, Bobak CA, Weiner JA, Wieland-Alter W, Lee J, Bloch EM, Tobian AAR, Redd AD, Blankson JN, Wolf D, Goetghebuer T, Marchant A, Connor RI, Wright PF, Ackerman ME |
medRxiv : the preprint server for health sciences | 2021 |
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Comparative performance of multiplex salivary and commercially available serologic assays to detect SARS-CoV-2 IgG and neutralization titers
Heaney CD, Pisanic N, Randad PR, Kruczynski K, Howard T, Zhu X, Littlefield K, Patel EU, Shrestha R, Laeyendecker O, Shoham S, Sullivan D, Gebo K, Hanley D, Redd AD, Quinn TC, Casadevall A, Zenilman JM, Pekosz A, Bloch EM, Tobian AA |
2021 | |
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CD8+ T cell responses in COVID-19 convalescent individuals target conserved epitopes from multiple prominent SARS-CoV-2 circulating variants
Redd AD, Nardin A, Kared H, Bloch EM, Pekosz A, Laeyendecker O, Abel B, Fehlings M, Quinn TC, Tobian AA |
2021 | |
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Minimal cross-over between mutations associated with Omicron variant of SARS-CoV-2 and CD8+ T cell epitopes identified in COVID-19 convalescent individuals
Redd AD, Nardin A, Kared H, Bloch EM, Abel B, Pekosz A, Laeyendecker O, Fehlings M, Quinn TC, Tobian AA |
2021 | |
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Functional Antibodies in COVID-19 Convalescent Plasma.
Herman JD, Wang C, Loos C, Yoon H, Rivera J, Dieterle ME, Haslwanter D, Jangra RK, Bortz RH 3rd, Bar KJ, Julg B, Chandran K, Lauffenburger D, Pirofski LA, Alter G |
medRxiv : the preprint server for health sciences | 2021 |
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Randomized controlled trial transfusing convalescent plasma as post-exposure prophylaxis against SARS-CoV-2 infection.
Shoham S, Bloch EM, Casadevall A, Hanley D, Lau B, Gebo K, Cachay E, Kassaye SG, Paxton JH, Gerber J, Levine AC, Currier J, Patel B, Allen ES, Anjan S, Appel L, Baksh S, Blair PW, Bowen A, Broderick P, Caputo CA, Cluzet V, Cordisco ME, Cruser D, Ehrhardt S, Forthal D, Fukuta Y, Gawad AL, Gniadek T, Hammel J, Huaman MA, Jabs DA, Jedlicka A, Karlen N, Klein S, Laeyendecker O, Lane K, McBee N, Meisenberg B, Merlo C, Mosnaim G, Park HS, Pekosz A, Petrini J, Rausch W, Shade DM, Shapiro JR, Singleton JR, Sutcliffe C, Thomas DL, Yarava A, Zand M, Zenilman JM, Tobian AAR, Sullivan D |
medRxiv : the preprint server for health sciences | 2021 |
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Randomized Controlled Trial of Early Outpatient COVID-19 Treatment with High-Titer Convalescent Plasma.
Sullivan DJ, Gebo KA, Shoham S, Bloch EM, Lau B, Shenoy AG, Mosnaim GS, Gniadek TJ, Fukuta Y, Patel B, Heath SL, Levine AC, Meisenberg BR, Spivak ES, Anjan S, Huaman MA, Blair JE, Currier JS, Paxton JH, Gerber JM, Petrini JR, Broderick PB, Rausch W, Cordisco ME, Hammel J, Greenblatt B, Cluzet VC, Cruser D, Oei K, Abinante M, Hammitt LL, Sutcliffe CG, Forthal DN, Zand MS, Cachay ER, Raval JS, Kassaye SG, Foster EC, Roth M, Marshall CE, Yarava A, Lane K, McBee NA, Gawad AL, Karlen N, Singh A, Ford DE, Jabs DA, Appel LJ, Shade DM, Ehrhardt S, Baksh SN, Laeyendecker O, Pekosz A, Klein SL, Casadevall A, Tobian AAR, Hanley DF |
medRxiv : the preprint server for health sciences | 2021 |
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Male sex and age biases viral burden, viral shedding, and type 1 and 2 interferon responses during SARS-CoV-2 infection in ferrets.
Francis ME, Richardson B, McNeil M, Rioux M, Foley MK, Ge A, Pechous RD, Kindrachuk J, Cameron CM, Richardson C, Lew J, Cameron MJ, Gerdts V, Falzarano D, Kelvin AA |
bioRxiv : the preprint server for biology | 2021 |
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Neutralizing IFNL3 Autoantibodies in Severe COVID-19 Identified Using Molecular Indexing of Proteins by Self-Assembly.
Credle JJ, Gunn J, Sangkhapreecha P, Monaco DR, Zheng XA, Tsai HJ, Wilbon A, Morgenlander WR, Dong Y, Jayaraman S, Tosi L, Parekkadan B, Baer AN, Roederer M, Bloch EM, Tobian AAR, Zyskind I, Silverberg JI, Rosenberg AZ, Cox AL, Lloyd T, Mammen AL, Larman HB |
bioRxiv : the preprint server for biology | 2021 |
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Assessment of serological assays for identifying high titer convalescent plasma.
Farnsworth CW, Case JB, Hock K, Chen RE, O'Halloran JA, Presti R, Goss CW, Rauseo AM, Ellebedy A, Theel ES, Diamond MS, Henderson JP |
medRxiv : the preprint server for health sciences | 2021 |
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SARS-CoV-2 serology across scales: a framework for unbiased seroprevalence estimation incorporating antibody kinetics and epidemic recency.
Takahashi S, Peluso MJ, Hakim J, Turcios K, Janson O, Routledge I, Busch MP, Hoh R, Tai V, Kelly JD, Martin JN, Deeks SG, Henrich TJ, Greenhouse B, Rodríguez-Barraquer I |
medRxiv : the preprint server for health sciences | 2021 |
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Differentiation of SARS-CoV-2 naturally infected and vaccinated individuals in an inner-city emergency department.
Beck EJ, Hsieh YH, Fernandez RE, Dashler G, Egbert ER, Truelove SA, Garliss C, Wang R, Bloch EM, Shrestha R, Blankson J, Cox AL, Manabe YC, Kickler T, Rothman RE, Redd AD, Tobian AA, Milstone AM, Quinn TC, Laeyendecker O |
medRxiv : the preprint server for health sciences | 2021 |
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Convalescent plasma anti-SARS-CoV-2 spike protein ectodomain and receptor binding domain IgG correlate with virus neutralization
Eric Salazar, Suresh V. Kuchipudi, Paul A. Christensen, Todd Eagar, Xin Yi, Picheng Zhao, Zhicheng Jin, S. Wesley Long, Randall J. Olsen, Jian Chen, Brian Castillo, Christopher Leveque, Dalton Towers, Jason J. Lavinder, Jimmy Gollihar, Jose A. Cardona, Gregory C. Ippolito, Ruth H. Nissly, Ian Bird, Denver Greenawalt, Randall M. Rossi, Abhinay Gontu, Sreenidhi Srinivasan, Indira Poojary, Isabella M. Cattadori, Peter Hudson, Nicole M. Josleyn, Laura Prugar, Kathleen E. Huie, Andrew S. Herbert, David W. Bernard, John M. Dye, Vivek Kapur, James M. Musser |
Journal of Clinical Investigation | 2020 |
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Auto-antibodies against type I IFNs in patients with life-threatening COVID-19
P Bastard, LB Rosen, Q Zhang, E Michailidis, HH Hoffmann, Y Zhang, K Dorgham, Q Philippot, J Rosain, V Béziat, J Manry, E Shaw, L Haljasmägi, P Peterson, L Lorenzo, L Bizien, S Trouillet-Assant, K Dobbs, AA de Jesus, A Belot, A Kallaste, E Catherinot, Y Tandjaoui-Lambiotte, JL Pen, G Kerner, B Bigio, Y Seeleuthner, R Yang, A Bolze, AN Spaan, OM Delmonte, MS Abers, A Aiuti, G Casari, V Lampasona, L Piemonti, F Ciceri, K Bilguvar, RP Lifton, M Vasse, DM Smadja, M Migaud, J Hadjadj, B Terrier, D Duffy, L Quintana-Murci, D van de Beek, L Roussel, DC Vinh, SG Tangye, F Haerynck, D Dalmau, J Martinez-Picado, P Brodin, MC Nussenzweig, S Boisson-Dupuis, C Rodríguez-Gallego, G Vogt, TH Mogensen, AJ Oler, J Gu, PD Burbelo, J Cohen, A Biondi, LR Bettini, M D'Angio, P Bonfanti, P Rossignol, J Mayaux, F Rieux-Laucat, ES Husebye, F Fusco, MV Ursini, L Imberti, A Sottini, S Paghera, E Quiros-Roldan, C Rossi, R Castagnoli, D Montagna, A Licari, GL Marseglia, X Duval, J Ghosn, JS Tsang, R Goldbach-Mansky, K Kisand, MS Lionakis, A Puel, SY Zhang, SM Holland, G Gorochov, E Jouanguy, CM Rice, A Cobat, LD Notarangelo, L Abel, HC Su, JL Casanova |
Science | 2020 |
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Understanding the complexities of SARS-CoV2 infection and its immunology: A road to immune-based therapeutics
V Kumar |
International Immunopharmacology | 2020 |
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Cytokine and Chemokine Levels in Coronavirus Disease 2019 Convalescent Plasma
TS Bonny, EU Patel, X Zhu, EM Bloch, MK Grabowski, AG Abraham, K Littlefield, R Shrestha, SE Benner, O Laeyendecker, S Shoham, D Sullivan, TC Quinn, A Casadevall, A Pekosz, AD Redd, AA Tobian |
Open Forum Infectious Diseases | 2020 |
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SARS-CoV-2 Antibody Avidity Responses in COVID-19 Patients and Convalescent Plasma Donors
SE Benner, EU Patel, O Laeyendecker, A Pekosz, K Littlefield, Y Eby, RE Fernandez, J Miller, CS Kirby, M Keruly, E Klock, OR Baker, HA Schmidt, R Shrestha, I Burgess, TS Bonny, W Clarke, P Caturegli, D Sullivan, S Shoham, TC Quinn, EM Bloch, A Casadevall, AA Tobian, AD Redd |
The Journal of Infectious Diseases | 2020 |
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Role of ACE2 receptor and the landscape of treatment options from convalescent plasma therapy to the drug repurposing in COVID-19
P Kumar, AK Sah, G Tripathi, A Kashyap, A Tripathi, R Rao, PC Mishra, K Mallick, A Husain, MK Kashyap |
Molecular and Cellular Biochemistry | 2020 |
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Measures of infection prevention and incidence of SARS-CoV-2 infections in cancer patients undergoing radiotherapy in Germany, Austria and Switzerland
C Matuschek, JC Fischer, SE Combs, R Fietkau, S Corradini, K Zänker, E Bölke, FJ Djiepmo-Njanang, B Tamaskovics, JE Fischer, M Stuschke, C Pöttgen, R Förster, DR Zwahlen, A Papachristofilou, U Ganswindt, R Pelka, EM Schneider, T Feldt, BE Jensen, D Häussinger, WT Knoefel, D Kindgen-Milles, A Pedoto, O Grebe, M van Griensven, W Budach, J Haussmann |
Strahlentherapie und Onkologie | 2020 |
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The Assessment of Convalescent Plasma Efficacy against COVID-19
A Casadevall, BJ Grossman, JP Henderson, MJ Joyner, S Shoham, L Pirofski, N Paneth |
The American Journal of Medicine | 2020 |
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Convalescent Plasma Therapy for COVID-19: State of the Art
D Focosi, AO Anderson, JW Tang, M Tuccori |
Clinical microbiology reviews | 2020 |
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Neutralizing antibodies against SARS-CoV-2: current understanding, challenge and perspective
Y Huang, H Sun, H Yu, S Li, Q Zheng, N Xia |
2020 | |
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A retrospective study assessing the characteristics of COVID‐19 convalescent plasma donors and donations
CD Fante, M Franchini, F Baldanti, E Percivalle, C Glingani, G Marano, C Mengoli, C Mortellaro, G Viarengo, C Perotti, GM Liumbruno |
Transfusion | 2020 |
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Viral infection neutralization tests: A focus on severe acute respiratory syndrome‐coronavirus‐2 with implications for convalescent plasma therapy
D Focosi, F Maggi, P Mazzetti, M Pistello |
Reviews in Medical Virology | 2020 |
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Multi-center nationwide comparison of seven serology assays reveals a SARS-CoV-2 non-responding seronegative subpopulation
K Oved, L Olmer, Y Shemer-Avni, T Wolf, L Supino-Rosin, G Prajgrod, Y Shenhar, I Payorsky, Y Cohen, Y Kohn, V Indenbaum, R Lazar, V Geylis, MT Oikawa, E Shinar, E Stoyanov, L Keinan-Boker, R Bassal, S Reicher, R Yishai, A Bar-Chaim, R Doolman, Y Reiter, E Mendelson, Z Livneh, LS Freedman, Y Lustig |
2020 | |
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Evaluating SARS-CoV-2 Seroconversion Following Relieve of Confinement Measures
J Gonçalves, RL Sousa, MJ Jacinto, DA Silva, F Paula, R Sousa, S Zahedi, J Carvalho, MG Cabral, M Costa, JC Branco, H Canhão, JD Alves, AM Rodrigues, H Soares |
Frontiers in Medicine | 2020 |
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Disentangling the dynamical underpinnings of differences in SARS-CoV-2 pathology using within-host ecological models
CJ Metcalf, BT Grenfell, AL Graham, S Lakdawala |
PLoS pathogens | 2020 |
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Convalescent plasma for COVID-19: male gender, older age and hospitalisation associated with high neutralising antibody levels, England, 22 April to 12 May 2020
J Mehew, R Johnson, D Roberts, H Harvala |
Euro surveillance : bulletin europeen sur les maladies transmissibles = European communicable disease bulletin | 2020 |
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Longitudinal Serological Analysis and Neutralizing Antibody Levels in Coronavirus Disease 2019 Convalescent Patients
F Muecksch, H Wise, B Batchelor, M Squires, E Semple, C Richardson, J McGuire, S Clearly, E Furrie, N Greig, G Hay, K Templeton, JC Lorenzi, T Hatziioannou, S Jenks, PD Bieniasz |
The Journal of Infectious Diseases | 2020 |
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Sex-biased Immune Responses Following SARS-CoV-2 Infection
RL Ursin, JR Shapiro, SL Klein |
Trends in Microbiology | 2020 |
|
Antibody responses to SARS-CoV-2 in patients with differing severities of coronavirus disease 2019
E Kowitdamrong, T Puthanakit, W Jantarabenjakul, E Prompetchara, P Suchartlikitwong, O Putcharoen, N Hirankarn, WR Taylor |
PloS one | 2020 |
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Susceptibility of tree shrew to SARS-CoV-2 infection
Y Zhao, J Wang, D Kuang, J Xu, M Yang, C Ma, S Zhao, J Li, H Long, K Ding, J Gao, J Liu, H Wang, H Li, Y Yang, W Yu, J Yang, Y Zheng, D Wu, S Lu, H Liu, X Peng |
Scientific Reports | 2020 |
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Metabolic programs define dysfunctional immune responses in severe COVID-19 patients
Thompson EA, Cascino K, Ordonez AA, Zhou W, Vaghasia A, Hamacher-Brady A, Brady NR, Sun IH, Wang R, Rosenberg AZ, Delannoy M, Rothman R, Fenstermacher K, Sauer L, Shaw-Saliba K, Bloch EM, Redd AD, Tobian AA, Horton M, Smith K, Pekosz A, D\u2019Alessio FR, Yegnasubramanian S, Ji H, Cox AL, Powell JD |
2020 | |
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Comparative performance of five commercially available serologic assays to detect antibodies to SARS-CoV-2 and identify individuals with high neutralizing titers.
Patel EU, Bloch EM, Clarke W, Hsieh YH, Boon D, Eby Y, Fernandez RE, Baker OR, Keruly M, Kirby CS, Klock E, Littlefield K, Miller J, Schmidt HA, Sullivan P, Piwowar-Manning E, Shrestha R, Redd AD, Rothman RE, Sullivan D, Shoham S, Casadevall A, Quinn TC, Pekosz A, Tobian AAR, Laeyendecker O |
medRxiv : the preprint server for health sciences | 2020 |
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SARS-CoV-2 antibody signatures robustly predict diverse antiviral functions relevant for convalescent plasma therapy
Natarajan H, Crowley AR, Butler SE, Xu S, Weiner JA, Bloch EM, Littlefield K, Wieland-Alter W, Connor RI, Wright PF, Benner SE, Bonny TS, Laeyendecker O, Sullivan D, Shoham S, Quinn TC, Larman HB, Casadevall A, Pekosz A, Redd AD, Tobian AA, Ackerman ME |
2020 | |
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Antibody responses to endemic coronaviruses modulate COVID-19 convalescent plasma functionality
Morgenlander W, Henson S, Monaco D, Chen A, Littlefield K, Bloch EM, Fujimura E, Ruczinski I, Crowley AR, Natarajan H, Butler SE, Weiner JA, Li MZ, Bonny TS, Benner SE, Ashwin Balagopal, Sullivan D, Shoham S, Quinn TC, Eshleman S, Casadevall A, Redd AD, Laeyendecker O, Ackerman ME, Pekosz A, Elledge SJ, Robinson M, Tobian AA, Larman HB |
2020 | |
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Engineering luminescent biosensors for point-of-care SARS-CoV-2 antibody detection.
Elledge SK, Zhou XX, Byrnes JR, Martinko AJ, Lui I, Pance K, Lim SA, Glasgow JE, Glasgow AA, Turcios K, Iyer N, Torres L, Peluso MJ, Henrich TJ, Wang TT, Tato CM, Leung KK, Greenhouse B, Wells JA |
medRxiv : the preprint server for health sciences | 2020 |
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Longitudinal analysis of clinical serology assay performance and neutralising antibody levels in COVID19 convalescents.
Muecksch F, Wise H, Batchelor B, Squires M, Semple E, Richardson C, McGuire J, Clearly S, Furrie E, Neil G, Hay G, Templeton K, Lorenzi JCC, Hatziioannou T, Jenks S, Bieniasz PD |
medRxiv : the preprint server for health sciences | 2020 |
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Detection, prevalence, and duration of humoral responses to SARS-CoV-2 under conditions of limited population exposure.
Ripperger TJ, Uhrlaub JL, Watanabe M, Wong R, Castaneda Y, Pizzato HA, Thompson MR, Bradshaw C, Weinkauf CC, Bime C, Erickson HL, Knox K, Bixby B, Parthasarathy S, Chaudhary S, Natt B, Cristan E, Aini TE, Rischard F, Campion J, Chopra M, Insel M, Sam A, Knepler JL, Capaldi AP, Spier CM, Dake MD, Edwards T, Kaplan ME, Scott SJ, Hypes C, Mosier J, Harris DT, LaFleur BJ, Sprissler R, Nikolich-Žugich J, Bhattacharya D |
medRxiv : the preprint server for health sciences | 2020 |
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CD8+ T cell responses in convalescent COVID-19 individuals target epitopes from the entire SARS-CoV-2 proteome and show kinetics of early differentiation.
Kared H, Redd AD, Bloch EM, Bonny TS, Sumatoh H, Kairi F, Carbajo D, Abel B, Newell EW, Bettinotti MP, Benner SE, Patel EU, Littlefield K, Laeyendecker O, Shoham S, Sullivan D, Casadevall A, Pekosz A, Nardin A, Fehlings M, Tobian AA, Quinn TC |
bioRxiv : the preprint server for biology | 2020 |
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Durable SARS-CoV-2 B cell immunity after mild or severe disease.
Ogega CO, Skinner NE, Blair PW, Park HS, Littlefield K, Ganesan A, Ladiwala P, Antar AA, Ray SC, Betenbaugh MJ, Pekosz A, Klein SL, Manabe YC, Cox AL, Bailey JR |
medRxiv : the preprint server for health sciences | 2020 |
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The D614G Mutation Enhances the Lysosomal Trafficking of SARS-CoV-2 Spike.
Guo C, Tsai SJ, Ai Y, Li M, Pekosz A, Cox A, Atai N, Gould SJ |
bioRxiv : the preprint server for biology | 2020 |
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