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Citations to this article

Early safety indicators of COVID-19 convalescent plasma in 5000 patients
Michael J. Joyner, … , Peter Marks, Arturo Casadevall
Michael J. Joyner, … , Peter Marks, Arturo Casadevall
Published June 11, 2020
Citation Information: J Clin Invest. 2020;130(9):4791-4797. https://doi.org/10.1172/JCI140200.
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Early safety indicators of COVID-19 convalescent plasma in 5000 patients

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Abstract

BACKGROUND Convalescent plasma is the only antibody-based therapy currently available for patients with coronavirus disease 2019 (COVID-19). It has robust historical precedence and sound biological plausibility. Although promising, convalescent plasma has not yet been shown to be safe as a treatment for COVID-19.METHODS Thus, we analyzed key safety metrics after transfusion of ABO-compatible human COVID-19 convalescent plasma in 5000 hospitalized adults with severe or life-threatening COVID-19, with 66% in the intensive care unit, as part of the US FDA expanded access program for COVID-19 convalescent plasma.RESULTS The incidence of all serious adverse events (SAEs), including mortality rate (0.3%), in the first 4 hours after transfusion was <1%. Of the 36 reported SAEs, there were 25 reported incidences of related SAEs, including mortality (n = 4), transfusion-associated circulatory overload (n = 7), transfusion-related acute lung injury (n = 11), and severe allergic transfusion reactions (n = 3). However, only 2 of 36 SAEs were judged as definitely related to the convalescent plasma transfusion by the treating physician. The 7-day mortality rate was 14.9%.CONCLUSION Given the deadly nature of COVID-19 and the large population of critically ill patients included in these analyses, the mortality rate does not appear excessive. These early indicators suggest that transfusion of convalescent plasma is safe in hospitalized patients with COVID-19.TRIAL REGISTRATION ClinicalTrials.gov NCT04338360.FUNDING Mayo Clinic, Biomedical Advanced Research and Development Authority (75A50120C00096), National Center for Advancing Translational Sciences (UL1TR002377), National Heart, Lung, and Blood Institute (5R35HL139854 and R01 HL059842), National Institute of Diabetes and Digestive and Kidney Diseases (5T32DK07352), Natural Sciences and Engineering Research Council of Canada (PDF-532926-2019), National Institute of Allergy and Infectious Disease (R21 AI145356, R21 AI152318, and AI152078), Schwab Charitable Fund, United Health Group, National Basketball Association, Millennium Pharmaceuticals, and Octapharma USA Inc.

Authors

Michael J. Joyner, R. Scott Wright, DeLisa Fairweather, Jonathon W. Senefeld, Katelyn A. Bruno, Stephen A. Klassen, Rickey E. Carter, Allan M. Klompas, Chad C. Wiggins, John R.A. Shepherd, Robert F. Rea, Emily R. Whelan, Andrew J. Clayburn, Matthew R. Spiegel, Patrick W. Johnson, Elizabeth R. Lesser, Sarah E. Baker, Kathryn F. Larson, Juan G. Ripoll, Kylie J. Andersen, David O. Hodge, Katie L. Kunze, Matthew R. Buras, Matthew N.P. Vogt, Vitaly Herasevich, Joshua J. Dennis, Riley J. Regimbal, Philippe R. Bauer, Janis E. Blair, Camille M. Van Buskirk, Jeffrey L. Winters, James R. Stubbs, Nigel S. Paneth, Nicole C. Verdun, Peter Marks, Arturo Casadevall

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Journal of Clinical Investigation 2021
Treatment of Severe COVID-19 with Convalescent Plasma in Bronx, NYC
Hyun ah Yoon, Rachel Bartash, Inessa Gendlina, Johanna Rivera, Antonio Nakouzi, Robert H. Bortz III, Ariel S. Wirchnianski, Monika Paroder, Karen Fehn, Leana Serrano-Rahman, Rachelle Babb, Uzma N. Sarwar, Denise Haslwanter, Ethan Laudermilch, Catalina Florez, M. Eugenia Dieterle, Rohit K Jangra, J. Maximilian Fels, Karen Tong, Margarette C. Mariano, Olivia Vergnolle, George I. Georgiev, Natalia G. Herrera, Ryan J. Malonis, Jose A. Quiroz, Nicholas C. Morano, Gregory J. Krause, Joseph M. Sweeney, Kelsie Cowman, Stephanie A Allen, Jayabhargav Annam, Ariella Applebaum, Daniel Barboto, Ahmed Khokhar, Brianna J. Lally, Audrey Lee, Max Lee, Avinash Malaviya, Reise Sample, Xiuyi A Yang, Yang Li, Rafael E Ruiz, Raja Thota, Jason Barnhill, Doctor Y. Goldstein, Joan Uehlinger, Scott J. Garforth, Steven C. Almo, Jonathan R. Lai, Morayma Reyes Gil, Amy S. Fox, Kartik Chandran, Tao Wang, Johanna P Daily, Liise-anne Pirofski
JCI Insight 2021
Clinical and laboratory evaluation of patients with SARS-CoV-2 pneumonia treated with high-titer convalescent plasma
Michele Donato, Steven Park, Melissa Baker, Robert Korngold, Alison Morawski, Xue Geng, Ming Tan, Andrew Ip, Stuart Goldberg, Scott D. Rowley, Kar F Chow, Emily Brown, Joshua Zenreich, Phyllis McKiernan, Kathryn Buttner, Anna Ullrich, Laura Long, Rena Feinman, Andrea Ricourt, Marlo Kemp, Mariefel Vendivil, Hyung C. Suh, Bindu Balani, Cristina Cicogna, Rani Sebti, Abdulla Al-Khan, Steven J. Sperber, Samit Desai, Stacey L. Fanning, Danit Arad, Ronaldo C. Go, Elizabeth Tam, Keith Rose, Sean Sadikot, David S Siegel, Martin Gutierrez, Tatyana Feldman, Andre Goy, Andrew Pecora, Noa Biran, Lori A. Leslie, Alfred Gillio, Sarah Timmapuri, Michele S. Boonstra, Sam Singer, Sukhdeep Kaur, Ernest Richards, David S Perlin
JCI Insight 2021
Neutralization of SARS-CoV-2 with IgG from COVID-19-convalescent plasma
K Maeda, N Higashi-Kuwata, N Kinoshita, S Kutsuna, K Tsuchiya, S Hattori, K Matsuda, Y Takamatsu, H Gatanaga, S Oka, H Sugiyama, N Ohmagari, H Mitsuya
Scientific Reports 2021
Potent prophylactic and therapeutic efficacy of recombinant human ACE2-Fc against SARS-CoV-2 infection in vivo
Z Zhang, E Zeng, L Zhang, W Wang, Y Jin, J Sun, S Huang, W Yin, J Dai, Z Zhuang, Z Chen, J Sun, A Zhu, F Li, W Cao, X Li, Y Shi, M Gan, S Zhang, P Wei, J Huang, N Zhong, G Zhong, J Zhao, Y Wang, W Shao, J Zhao
Cell Discovery 2021
Convalescent plasma is of limited clinical benefit in critically ill patients with coronavirus disease-2019: a cohort study
L Huang, C Zhang, X Zhou, Z Zhao, W Wang, W Leng, X Su, Q Lian
Journal of Translational Medicine 2021
Nasal Administration of Anti-CD3 Monoclonal Antibody (Foralumab) Reduces Lung Inflammation and Blood Inflammatory Biomarkers in Mild to Moderate COVID-19 Patients: A Pilot Study
TG Moreira, KT Matos, GS Paula, TM Santana, RG Mata, FC Pansera, AS Cortina, MG Spinola, GD Keppeke, J Jacob, V Palejwala, K Chen, S Izzy, BC Healey, RM Rezende, RA Dedivitis, K Shailubhai, HL Weiner
Frontiers in immunology 2021
Impact of serological and PCR testing requirements on the selection of COVID ‐19 convalescent plasma donors
JA Carter, AT Freedenberg, JL Romeiser, LR Talbot, NJ Browne, ME Cosgrove, ME Shevik, LM Generale, MG Rago, GA Caravella, T Ahmed, LJ Mamone, E BennettGuerrero
Transfusion 2021
COVID-19 convalescent plasma composition and immunological effects in severe patients
Y Acosta-Ampudia, DM Monsalve, M Rojas, Y Rodríguez, JE Gallo, JC Salazar-Uribe, MJ Santander, MP Cala, W Zapata, MI Zapata, R Manrique, JM Pardo-Oviedo, B Camacho, C Ramírez-Santana, JM Anaya
Journal of Autoimmunity 2021
Decay of Fc-dependent antibody functions after mild to moderate COVID-19
WS Lee, KJ Selva, SK Davis, BD Wines, A Reynaldi, R Esterbauer, HG Kelly, ER Haycroft, HX Tan, JA Juno, AK Wheatley, PM Hogarth, D Cromer, MP Davenport, AW Chung, SJ Kent
Reproduction 2021
Fc-engineered antibody therapeutics with improved efficacy against COVID-19
Jeffrey Ravetch, Rachel Yamin, Andrew Jones, Hans-Heinrich Hoffmann, Kevin Kao, Rebecca Francis, Timothy Sheahan, Ralph Baric, Charles Rice, Stylianos Bournazos
Research square 2021
Convalescent Plasma for Infectious Diseases: Historical Framework and Use in COVID-19
JG Ripoll, N van Helmond, JW Senefeld, CC Wiggins, SA Klassen, SE Baker, KF Larson, BM Murphy, KJ Andersen, SK Ford, A Casadevall, MJ Joyner
Clinical Microbiology Newsletter 2021
SARS-CoV-2: vaccines in the pandemic era
DD Li, QH Li
Military Medical Research 2021
A look-back at convalescent plasma to treat COVID-19
O Garraud, K Lacombe, P Tiberghien
Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis 2021
A review of COVID-19 convalescent plasma use in COVID-19 with focus on proof of efficacy
PK Devarasetti, L Rajasekhar, R Baisya, KS Sreejitha, YK Vardhan
Immunologic Research 2021
Use of convalescent serum reduces severity of COVID-19 in nonhuman primates
RW Cross, AN Prasad, V Borisevich, C Woolsey, KN Agans, DJ Deer, NS Dobias, JB Geisbert, KA Fenton, TW Geisbert
Cell Reports 2021
Integrative overview of antibodies against SARS-CoV-2 and their possible applications in COVID-19 prophylaxis and treatment
NA Valdez-Cruz, E García-Hernández, C Espitia, L Cobos-Marín, C Altamirano, CG Bando-Campos, LF Cofas-Vargas, EW Coronado-Aceves, RA González-Hernández, P Hernández-Peralta, D Juárez-López, PA Ortega-Portilla, S Restrepo-Pineda, P Zelada-Cordero, MA Trujillo-Roldán
Microbial cell factories 2021
Convalescent plasma for adults with acute COVID-19 respiratory illness (CONCOR-1): study protocol for an international, multicentre, randomized, open-label trial
P Bégin, J Callum, NM Heddle, R Cook, MP Zeller, A Tinmouth, DA Fergusson, MM Cushing, MJ Glesby, M Chassé, DV Devine, N Robitalle, R Bazin, N Shehata, A Finzi, A McGeer, DC Scales, L Schwartz, AF Turgeon, R Zarychanski, N Daneman, R Carl, L Amorim, C Gabe, M Ellis, BS Sachais, KC Loftsgard, E Jamula, J Carruthers, J Duncan, K Lucier, N Li, Y Liu, C Armali, A Kron, D Modi, MC Auclair, S Cerro, M Avram, DM Arnold
Trials 2021
Convalescent plasma therapy in B-cell-depleted and B-cell sufficient patients with life-threatening COVID-19 – A case series
J Erber, JR Wiessner, C Huberle, J Schneider, H Mijočević, D von Bomhard, P Luppa, RM Schmid, S Rasch, T Lahmer
Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis 2021
Promising Immunotherapies against COVID‐19
H Guo, L Zhou, Z Ma, Z Tian, F Zhou
2021
Recent advances in antibody‐based immunotherapy strategies for COVID‐19
A Esmaeilzadeh, S Rostami, PM Yeganeh, S Tahmasebi, M Ahmadi
Journal of Cellular Biochemistry 2021
Functional convalescent plasma antibodies and pre-infusion titers shape the early severe COVID-19 immune response
JD Herman, C Wang, C Loos, H Yoon, J Rivera, ME Dieterle, D Haslwanter, RK Jangra, RH Bortz, KJ Bar, B Julg, K Chandran, D Lauffenburger, L Pirofski, G Alter
Nature Communications 2021
The Journal of Clinical Investigation in the time of COVID-19
A Casadevall, S Jackson, GL Semenza, GF Tomaselli, RS Ahima
Journal of Clinical Investigation 2021
Convalescent Plasma Therapy for COVID-19: A Graphical Mosaic of the Worldwide Evidence
SA Klassen, JW Senefeld, KA Senese, PW Johnson, CC Wiggins, SE Baker, N van Helmond, KA Bruno, L Pirofski, S Shoham, BJ Grossman, JP Henderson, RS Wright, DL Fairweather, NS Paneth, RE Carter, A Casadevall, MJ Joyner
Frontiers in Medicine 2021
The Effect of Convalescent Plasma Therapy on Mortality Among Patients With COVID-19: Systematic Review and Meta-analysis
SA Klassen, JW Senefeld, PW Johnson, RE Carter, CC Wiggins, S Shoham, BJ Grossman, JP Henderson, J Musser, E Salazar, WR Hartman, NM Bouvier, ST Liu, L Pirofski, SE Baker, N van Helmond, RS Wright, DL Fairweather, KA Bruno, Z Wang, NS Paneth, A Casadevall, MJ Joyner
Mayo Clinic Proceedings 2021
Are We Forgetting About IgA? A Re‐examination of Coronavirus Disease 2019 Convalescent Plasma
H Verkerke, BJ Saeedi, D Boyer, JW Allen, J Owens, S Shin, M Horwath, K Patel, A Paul, SC Wu, J Wang, A Ho, CL Maier, PE Zerra, S Chonat, CM Arthur, JD Roback, AS Neish, C Lough, CD Josephson, SR Stowell
Transfusion 2021
Convalescent Plasma for the Prevention and Treatment of COVID-19: A Systematic Review and Quantitative Analysis
HT Peng, SG Rhind, A Beckett
2021
Intravenous Immunoglobulins at the Crossroad of Autoimmunity and Viral Infections
C Perricone, P Triggianese, R Bursi, G Cafaro, E Bartoloni, MS Chimenti, R Gerli, R Perricone
Microorganisms 2021
Elevated cytokines and chemokines in peripheral blood of patients with SARS-CoV-2 pneumonia treated with high-titer convalescent plasma
SL Fanning, R Korngold, Z Yang, K Goldgirsh, S Park, J Zenreich, M Baker, P McKiernan, M Tan, B Zhang, ML Donato, DS Perlin, SR Shih
PLoS pathogens 2021
Convalescent plasma or hyperimmune immunoglobulin for people with COVID-19: a living systematic review
V Piechotta, C Iannizzi, KL Chai, SJ Valk, C Kimber, E Dorando, I Monsef, EM Wood, AA Lamikanra, DJ Roberts, Z McQuilten, C So-Osman, LJ Estcourt, N Skoetz
Cochrane Database of Systematic Reviews 2021
Regulatory challenges of convalescent plasma collection during the evolving stages of COVID ‐19 pandemic in the United States
S Hassan, KA West, K ConryCantilena, VD Giorgi
Transfusion 2021
Convalescent Plasma Antibody Levels and the Risk of Death from Covid-19
MJ Joyner, RE Carter, JW Senefeld, SA Klassen, JR Mills, PW Johnson, ES Theel, CC Wiggins, KA Bruno, AM Klompas, ER Lesser, KL Kunze, MA Sexton, JC Soto, SE Baker, JR Shepherd, N van Helmond, NC Verdun, P Marks, CM van Buskirk, JL Winters, JR Stubbs, RF Rea, DO Hodge, V Herasevich, ER Whelan, AJ Clayburn, KF Larson, JG Ripoll, KJ Andersen, MR Buras, MN Vogt, JJ Dennis, RJ Regimbal, PR Bauer, JE Blair, NS Paneth, DL Fairweather, RS Wright, A Casadevall
New England Journal of Medicine 2021
Comparative Performance of Five Commercially Available Serologic Assays To Detect Antibodies to SARS-CoV-2 and Identify Individuals with High Neutralizing Titers
EU Patel, EM Bloch, W Clarke, YH Hsieh, D Boon, Y Eby, RE Fernandez, OR Baker, M Keruly, CS Kirby, E Klock, K Littlefield, J Miller, HA Schmidt, P Sullivan, E Piwowar-Manning, R Shrestha, AD Redd, RE Rothman, D Sullivan, S Shoham, A Casadevall, TC Quinn, A Pekosz, AA Tobian, O Laeyendecker, MJ Loeffelholz
Journal of clinical microbiology 2021
COVID ‐19 convalescent plasma: Interim recommendations from the AABB
CS Cohn, L Estcourt, BJ Grossman, MB Pagano, ES Allen, EM Bloch, A Casadevall, DV Devine, NM Dunbar, F Foroutan, TJ Gniadek, R Goel, J Gorlin, MJ Joyner, RA Metcalf, JS Raval, TW Rice, BH Shaz, RR Vassallo, JL Winters, G Beaudoin, AA Tobian
Transfusion 2021
Convalescent Plasma Therapy in Critically Ill COVID-19 Patients: An Open Label Trial
F Khamis, ZA Arimi, HA Naamani, MA Bahrani, N Pandak, ZA Bolushi, SS Deenadayalan, AA Lawati, IA Salmi, I Al-Zakwani
Oman Medical Journal 2021
A Narrative Review of a Pulmonary Aerosolized Formulation or a Nasal Drop Using Sera Containing Neutralizing Antibodies Collected from COVID-19-Recovered Patients as a Probable Therapy for COVID-19
Nishat Fatima, Vichitra Kaushik, Amjad Ayoub
Iranian journal of medical sciences 2021
Convalescent plasma therapy as a conventional trick for treating COVID-19: a systematic review and meta-analysis study
M Keikha, M Karbalaei
New Microbes and New Infections 2021
Preparedness and activities of the anti-SARS-CoV-2 convalescent plasma bank in the Veneto region (Italy): An organizational model for future emergencies
GD Silvestro, G Gandini, F Fiorin, P Marson, E Barbone, A Frigato, G Gessoni, A Veronesi, M Pacenti, M Castelli, M Rinaldi, M Rizzi, F Stefani, G Roveroni
Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis 2021
Use of convalescent plasma for COVID-19 in India: A review & practical guidelines
NS Khaire, N Jindal, LN Yaddanapudi, S Sachdev, R Hans, N Sachdeva, MP Singh, A Agarwal, A Mukherjee, G Kumar, RR Sharma, V Suri, GD Puri, P Malhotra
The Indian journal of medical research 2021
Convalescent blood plasma (CBP) donated by recovered COVID-19 patients – A comment
T Lung, B Sakem, M Risch, U Nydegger
Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis 2021
Digital Health Surveillance Strategies for Management of Coronavirus Disease 2019
T Jose, DO Warner, JC OHoro, SG Peters, R Chaudhry, MJ Binnicker, CD Burger
2021
Safety and Efficacy of Convalescent Plasma for Severe COVID-19: Interim Report of a Multicenter Phase II Study from Saudi Arabia
N AlShehry, SZ Zaidi, A AlAskar, AA Odayani, JM Alotaibi, A AlSagheir, A Al-Eyadhy, S Balelah, A Salam, AR Zaidi, D Alawami, MS Alshahrani, N AlMozain, YM Abulhamayel, RA Qunfoidi, M Alfaraj, N Qushmaq, R Alansari, A Dayel, G Elgohary, AA Bahrani, AA Abdelhameed, HA AlZahrani, H Alturkistani, N AlShehry, MA Albalawi, I Elalfy, H Alhumaidan, H Al-Hashmi
2021
Effect of convalescent blood products for patients with severe acute respiratory infections of viral etiology: A systematic review and meta-analysis
S Shao, Y Wang, H Kang, Z Tong
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases 2021
Two patients with rituximab associated low gammaglobulin levels and relapsed covid-19 infections treated with convalescent plasma
IO Vélez, JI Bermejo, JE Pérez, LI Aguayo, MD Ruiz, JA García-Erce
Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis 2021
Quantifying Absolute Neutralization Titers against SARS-CoV-2 by a Standardized Virus Neutralization Assay Allows for Cross-Cohort Comparisons of COVID-19 Sera
KY Oguntuyo, CS Stevens, CT Hung, S Ikegame, JA Acklin, SS Kowdle, JC Carmichael, HP Chiu, KD Azarm, GD Haas, F Amanat, J Klingler, I Baine, S Arinsburg, JC Bandres, MN Siddiquey, RM Schilke, MD Woolard, H Zhang, AJ Duty, TA Kraus, TM Moran, D Tortorella, JK Lim, AV Gamarnik, CE Hioe, S Zolla-Pazner, SS Ivanov, JP Kamil, F Krammer, B Lee, K Subbarao
mBio 2021
SARS-CoV-2 infection: molecular mechanisms of severe outcomes to suggest therapeutics
N Hartog, W Faber, A Frisch, J Bauss, CP Bupp, S Rajasekaran, JW Prokop
Expert Review of Proteomics 2021
Passive Immunity Should and Will Work for COVID-19 for Some Patients:
N Cimolai
2021
Perspectives for immune plasma treatment of COVID-19
B SAYINALP, OE ÇINAR, İC HAZNEDAROĞLU
2021
The Principles of Antibody Therapy for Infectious Diseases with Relevance for COVID-19
A Casadevall, L Pirofski, MJ Joyner, DA Garsin
mBio 2021
Convalescent plasma use in the USA was inversely correlated with COVID-19 mortality
A Casadevall, Q Dragotakes, PW Johnson, JW Senefeld, SA Klassen, RS Wright, MJ Joyner, N Paneth, RE Carter
eLife 2021
The Effectiveness of Convalescent Plasma for the Treatment of Novel Corona Virus Disease 2019: A Systematic Review and Meta-Analysis
H Cao, L Ming, L Chen, X Zhu, Y Shi
Frontiers in Medicine 2021
Immunotherapy Summary for Cytokine Storm in COVID-19
Y Li, W Zhao, J Liu, Z Chen, Q Lv, Z Zhang
Frontiers in pharmacology 2021
Administration of high titer convalescent anti-SARS-CoV-2 plasma: From donor selection to monitoring recipient outcomes
RP Mendoza, W Fyke, D Daniel, E Gabutan, B Das, H Bajaj, M Easy, A Vasileva, R Colbourn, M Alawad, A Dehghani, B Lin, D Emechebe, P Patel, A Jabbar, DB Nikolov, D Giovaniello, S Kang, L Tatem, K Bromberg, M Augenbraun, P Premsrirut, J Libien, AJ Norin
Human Immunology 2021
Repositioned Drugs for COVID-19—the Impact on Multiple Organs
C Chan, ST Foster, KG Chan, MJ Cacace, SL Ladd, CT Sandum, PT Wright, B Volmert, W Yang, A Aguirre, W Li, NT Wright
2021
Further comments on the role of ACE ‐2 positive macrophages in human lung
W Hu, X Song, H Yu, L Zhao, Y Zhao, Y Zhao
Cytometry Part A 2021
Dynamics of antibodies to SARS‐CoV‐2 in convalescent plasma donors
M Steenhuis, G Mierlo, NI Derksen, PO Heer, S Kruithof, FL Loeff, LC Berkhout, F Linty, C Reusken, J Reimerink, B Hogema, H Zaaijer, L Watering, F Swaneveld, MJ Gils, BJ Bosch, SM Ham, A Brinke, G Vidarsson, EC Schoot, T Rispens
IBMS BoneKEy 2021
Assessment of anti‐SARS‐CoV‐2 antibodies level in convalescents plasma
A Skorek, A JaźwińskaCuryłło, A Romanowicz, K Kwaśniewski, W Narożny, D Tretiakow
Journal of Medical Virology 2021
Treating the endotheliopathy of SARS‐CoV ‐2 infection with plasma: Lessons learned from optimized trauma resuscitation with blood products
S Pati, E Fennern, JB Holcomb, M Barry, A Trivedi, AP Cap, MJ Martin, C Wade, R Kozar, JC Cardenas, JF Rappold, R Spiegel, MA Schreiber
Transfusion 2021
Hospital-Based Donor Recruitment and Predonation Serologic Testing for COVID-19 Convalescent Plasma
J Balcerek, E Trejo, K Levine, P Couey, ZV Kornberg, C Rogine, C Young, PJ Li, BR Shy, JE Taylor, S Bakhtary, T Friedlander, KL Lynch, C Bern, JH Esensten
American Journal of Clinical Pathology 2021
Aging in COVID-19: Vulnerability, immunity and intervention
Y Chen, SL Klein, BT Garibaldi, H Li, C Wu, NM Osevala, T Li, JB Margolick, G Pawelec, SX Leng
Ageing Research Reviews 2021
Immunological effects of convalescent plasma therapy for coronavirus: a scoping review
B Esmaeili, S Esmaeili, Z Pourpak
BMC Infectious Diseases 2021
Convalescence plasma treatment of COVID-19: results from a prematurely terminated randomized controlled open-label study in Southern Sweden
K Holm, MN Lundgren, J Kjeldsen-Kragh, O Ljungquist, B Böttiger, C Wikén, J Öberg, N Fernström, E Rosendal, AK Överby, JW Byström, M Forsell, M Landin-Olsson, M Rasmussen
BMC Research Notes 2021
Therapeutic Use of Convalescent Plasma in COVID-19 Infected Patients with Concomitant Hematological Disorders:
F Lanza, V Agostini, F Monaco, F Passamonti, J Seghatchian
2021
The importance of determining the amount of ‘therapeutic units’ before using convalescent plasma
YR Vieira, J Fernandes, MA Pinto, ER de Lemos, A Guterres
Future Virology 2021
Therapeutic antibodies under development for SARS‐CoV‐2
Z Ma, MM Zhu, S Zhang, K Qian, C Wang, W Fu, C Lei, S Hu
2021
Active surveillance of serious adverse events following transfusion of COVID ‐19 convalescent plasma
E Swenson, LK Wong, P Jhaveri, Y Weng, S Kappagoda, S Pandey, A Pritchard, A Rogers, S Ruoss, A Subramanian, H Shan, M Hollenhorst
Transfusion 2021
SARS-CoV-2: Current trends in emerging variants, pathogenesis, immune responses, potential therapeutic, and vaccine development strategies
A Salimi-Jeda, S Abbassi, A Mousavizadeh, M Esghaie, F Bokharaei-Salim, F Jeddi, M Shafaati, A Abdoli
International Immunopharmacology 2021
Convalescent plasma for SARS-CoV-2 infection: Win or Learn
E Contreras-Barbeta, A Millan, J Rello
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2021
Experience of Treating COVID-19 With Remdesivir and Convalescent Plasma in a Resource-Limited Setting: A Prospective, Observational Study
J Koirala, P Gyanwali, RB Gerzoff, S Bhattarai, B Nepal, R Manandhar, R Jha, S Sharma, YR Sharma, A Bastola, H Murphy, S Acharya, P Adhikari, M Rajkarnikari, KM Vaidya, CL Panthi, B Bista, G Giri, S Aryal, S Pant, A Pokharel, S Karki, S Basnet, B Koirala, M Dhimal, RK Jha, A Shrestha, A Dhungana, S Shrestha, S Pandey, S Shakya, PS Ranjit, S Dhungel, D Bhattarai, S Gautam, P Poudel, K Sapkota, KJ Shah, RK Mandal, R Pandey, S Prajapati, A Hussain, S Gupta, R Chhetri, K Pokharel, K Thapa, S Adhikari, GP Deo, B Gauli, P Ghimire, B Regmi, RB Gurung, R Shrestha, D Tamrakar, S Khanal, U Acharya, S Sapkota, R Shrestha, MJ Sijapati, S Koirala, S Bajracharya, D Sigdel, DP Acharya, S Chhetri, P Acharya, HP Panthi, A Dhungana, AR Karki, RK Singh, UN Singh, R Tiwari, A Hussain, R Shah, PA Ansari, D Aryal, SK Shrestha, K Koirala, KK KC, BP Acharya, S BK, S Pandey, SK Gupta, D Shakya, Y Sapkota, A Adhikari, B Koirala, B Karki, YR Sharma, BK Pandey, BS Lamichhane, S Shrestha, SB Kamar, A Chaudhary, J Joshi, K Sherpa, R Manandhar, C Pant, R Joshi, A Bastola, BS Chalise, SK Das, PS Shrestha
Open Forum Infectious Diseases 2021
Comparing antiviral strategies against COVID-19 via multiscale within-host modelling
F Fatehi, RJ Bingham, EC Dykeman, PG Stockley, R Twarock
Royal Society Open Science 2021
Effectiveness of Convalescent Plasma Therapy in Severe or Critically Ill COVID-19 Patients: A Retrospective Cohort Study
YS Cho, YJ Sohn, JH Hyun, YJ Baek, MH Kim, JH Kim, JY Ahn, SJ Jeong, NS Ku, JS Yeom, MY Ahn, DH Oh, JP Choi, SY Kim, KH Lee, YG Song, JY Choi
Yonsei Medical Journal 2021
Current advances in transfusion medicine 2020: A critical review of selected topics by the AABB Clinical Transfusion Medicine Committee
ES Allen, CS Cohn, S Bakhtary, NM Dunbar, T Gniadek, CK Hopkins, J Jacobson, PM Lokhandwala, RA Metcalf, C Murphy, MT Prochaska, JS Raval, H Shan, EK Storch, MB Pagano
Transfusion 2021
Multidimensional Evaluation of All-Cause Mortality Risk and Survival Analysis for Hospitalized Patients with COVID-19
J Li, H Luo, G Deng, J Chang, X Qiu, C Liu, B Qin
International journal of medical sciences 2021
COVID-19 challenges and its therapeutics
SU Rehman, SU Rehman, HH Yoo
Biomedicine & pharmacotherapy = Biomédecine & pharmacothérapie 2021
Inhibition of SARS-CoV-2 pseudovirus invasion by ACE2 protecting and Spike neutralizing peptides: An alternative approach to COVID19 prevention and therapy
J Chen, S Li, Z Lei, Q Tang, L Mo, X Zhao, F Xie, D Zi, J Tan
International journal of biological sciences 2021
Clinical Management of Adult Patients with COVID-19 Outside Intensive Care Units: Guidelines from the Italian Society of Anti-Infective Therapy (SITA) and the Italian Society of Pulmonology (SIP)
M Bassetti, DR Giacobbe, P Bruzzi, E Barisione, S Centanni, N Castaldo, S Corcione, FG Rosa, FD Marco, A Gori, A Gramegna, G Granata, A Gratarola, AE Maraolo, M Mikulska, A Lombardi, F Pea, N Petrosillo, D Radovanovic, P Santus, A Signori, E Sozio, E Tagliabue, C Tascini, C Vancheri, A Vena, P Viale, F Blasi, M Bassetti, DR Giacobbe, P Bruzzi, E Barisione, S Centanni, N Castaldo, S Corcione, FG Rosa, FD Marco, A Gori, A Gramegna, G Granata, A Gratarola, AE Maraolo, M Mikulska, A Lombardi, F Pea, N Petrosillo, D Radovanovic, P Santus, A Signori, E Sozio, E Tagliabue, C Tascini, C Vancheri, A Vena, P Viale, F Blasi
Infectious Diseases and Therapy 2021
HLA B53 is associated with a poor outcome in black COVID-19 patients
AJ Norin, R Mendoza, M Augenbraun, B Das
Human Immunology 2021
Making trials part of good clinical care: lessons from the RECOVERY trial
G Pessoa-Amorim, M Campbell, L Fletcher, P Horby, M Landray, M Mafham, R Haynes
2021
The safety of COVID ‐19 convalescent plasma donation: A multi‐institutional donor hemovigilance study
JH Cho, S Rajbhandary, NL Buren, MK Fung, M AlGhafry, JL Fridey, BA Dy, A Ziman, GB Schreiber, RR Gammon, R Reik, JR Stubbs, CM Buskirk, H Kamel, MJ Townsend, MP Zeller, JL Gottschall
Transfusion 2021
Dramatic Response to Convalescent Hyperimmune Plasma in Association With an Extended Course of Remdesivir in 4 B Cell–Depleted Non-Hodgkin Lymphoma Patients With SARS-Cov-2 Pneumonia After Rituximab Therapy
A Furlan, G Forner, L Cipriani, E Vian, R Rigoli, F Gherlinzoni, P Scotton
Clinical Lymphoma, Myeloma & Leukemia 2021
COVID ‐19 convalescent plasma cohort study: Evaluation of the association between both donor and recipient neutralizing antibody titers and patient outcomes
AP Yokoyama, S Wendel, C BonetBub, RM Fachini, AP Dametto, F Blumm, VF Dutra, GT Candelaria, AM Sakashita, RR Machado, R FontãoWendel, N Hamerschlak, R Achkar, MS Assunção, P Scuracchio, V Nudelman, L Pastore, JR Pinho, MD Ben, RK Filho, AR Marra, MT Amano, EG Kallás, AS Helito, CR Carvalho, DB Araujo, EL Durigon, AA Camargo, LV Rizzo, LF Reis, JM Kutner
Transfusion 2021
COVID-19 convalescent plasma therapy for immunodeficient patients–weighing up risks and benefits
T Vuk, A Hećimović, I Jukić, S Ravlić, T Kurtović, D Rnjak, B Halassy
Transfusion Clinique et Biologique 2021
Convalescent plasma as a treatment modality for Coronavirus Disease 2019 in Indonesia: A case reports
A Thabrani, WS Hadi, JA Thobari, Z Novianti, Kurniyanto, I Juliana, A Suharto, AN Danaswari, I Septiani, S Rhatomy
Annals of Medicine and Surgery 2021
Effectiveness of convalescent plasma therapy in a patient with severe COVID-19-associated acute kidney injury
ZZ Brener, A Brenner
Clinical Nephrology – Case Studies 2021
Necrotising myopathy and concurrent thyroiditis in a patient with COVID-19 infection
C Reggio, A Paudel, CS Specht, AA Donato
BMJ case reports 2021
Convalescent Plasma Efficacy in Life-Threatening COVID-19 Patients Admitted to the ICU: A Retrospective Cohort Study
M Abuzakouk, K Saleh, M Algora, A Nusair, J Alameri, F Alshehhi, S Alkhaja, M Badr, K Abdallah, BD Oliveira, A Nadeem, Y Varghese, D Munde, S Salam, B Abduljawad, H Elkambergy, A Wahla, A Taha, J Dibu, A Bayrlee, F Hamed, L AbdelWareth, N Rahman, J Guzman, J Mallat
Journal of Clinical Medicine 2021
Position paper on the use of COVID-19 convalescent plasma: an update
Daniele Prati, Francesco Fiorin, Pierluigi Berti, Giustina De Silvestro, Patrizia Accorsi, Angelo Ostuni,
Blood transfusion = Trasfusione del sangue 2021
Effects of potent neutralizing antibodies from convalescent plasma in patients hospitalized for severe SARS-CoV-2 infection
A Gharbharan, CC Jordans, C GeurtsvanKessel, JG den Hollander, F Karim, FP Mollema, JE Schukken, A Dofferhoff, I Ludwig, A Koster, RJ Hassing, JC Bos, GR van Pottelberge, IN Vlasveld, HS Ammerlaan, EM van Leeuwen Segarceanu, J Miedema, M van der Eerden, TJ Schrama, G Papageorgiou, P te Boekhorst, FH Swaneveld, YM Mueller, MW Schreurs, JJ van Kampen, B Rockx, NM Okba, PD Katsikis, MP Koopmans, BL Haagmans, C Rokx, BJ Rijnders
Nature Communications 2021
Randomized controlled trial of convalescent plasma therapy against standard therapy in patients with severe COVID-19 disease
M AlQahtani, A Abdulrahman, A Almadani, SY Alali, AM Zamrooni, AH Hejab, RM Conroy, P Wasif, S Otoom, SL Atkin, M Abduljalil
Scientific Reports 2021
What we have learned from the COVID-19 pandemic: Time to think outside the box, maybe far outside
WC Lambert, A Alhatem, MW Lambert, RA Schwartz
Clinics in Dermatology 2021
No Evidence for Human Monocyte-Derived Macrophage Infection and Antibody-Mediated Enhancement of SARS-CoV-2 Infection
O García-Nicolás, P Vkovski, F Zettl, G Zimmer, V Thiel, A Summerfield
Frontiers in Cellular and Infection Microbiology 2021
Convalescent plasma therapy - a silver lining for COVID-19 management?
S Saha, S Kadam
2021
Convalescent plasma therapy in COVID-19 critically ill patients during advanced phases of clinical trials and their preliminary results
FA de Oliveira, MP Nucci, GN de Albuquerque Rego, A da Hora Alves, LC Marti, LP Nucci, JB Mamani, LF Gamarra
Einstein (São Paulo) 2021
Suggested guidelines for convalescent plasma therapy for the treatment of COVID-19
GC Santis, A Mendrone, D Langhi, DT Covas, A Fabron, AJ Cortez, CL Dinardo, EM Ubiali, JF Marques, JO Bordin, MA Rugani
2021
Evaluation of the safety and efficacy of XAV-19 in patients with COVID-19-induced moderate pneumonia: study protocol for a randomized, double-blinded, placebo-controlled phase 2 (2a and 2b) trial
B Gaborit, B Vanhove, MA Vibet, AL Thuaut, K Lacombe, V Dubee, F Ader, V Ferre, E Vicaut, J Orain, ML Bras, A Omnes, L Berly, A Jobert, PM Houssine, K Botturi, R Josien, L Flet, N Degauque, S Brouard, O Duvaux, A Poinas, F Raffi
Trials 2021
Efficacy and Safety of Convalescent Plasma for COVID-19: A Systematic Review and Meta-analysis
M Prasad, T Seth, A Elavarasi
Indian Journal of Hematology and Blood Transfusion 2021
Passive Immunity Trial for Our Nation (PassITON): study protocol for a randomized placebo-control clinical trial evaluating COVID-19 convalescent plasma in hospitalized adults
WH Self, TG Stewart, AP Wheeler, WE Atrouni, AJ Bistran-Hall, JD Casey, VD Cataldo, JD Chappell, CS Cohn, JB Collins, MR Denison, M de Wit, SL Dixon, A Duggal, TL Edwards, MJ Fontaine, AA Ginde, MS Harkins, T Harrington, ES Harris, D Hoda, TS Ipe, SJ Jaiswal, NJ Johnson, AE Jones, M Laguio-Vila, CJ Lindsell, J Mallada, MJ Mammen, RA Metcalf, EA Middleton, S Mucha, HR ONeal, SR Pannu, JM Pulley, X Qiao, JS Raval, JP Rhoads, H Schrager, C Shanholtz, NI Shapiro, SJ Schrantz, I Thomsen, KK Vermillion, GR Bernard, TW Rice
Trials 2021
Establishment of a well-characterized SARS-CoV-2 lentiviral pseudovirus neutralization assay using 293T cells with stable expression of ACE2 and TMPRSS2
SN Neerukonda, R Vassell, R Herrup, S Liu, T Wang, K Takeda, Y Yang, TL Lin, W Wang, CD Weiss, NJ Mantis
PloS one 2021
SARS‐CoV‐2 and pediatric solid organ transplantation: Current knowns and unknowns
AG LHuillier, L DanzigerIsakov, A Chaudhuri, M Green, MG Michaels, K PosfayBarbe, D van der Linden, A Verma, M McCulloch, MI Ardura
Pediatric Transplantation 2021
Passive Immunity Trial for Our Nation (PassITON): study protocol for a randomized placebo-control clinical trial evaluating COVID-19 convalescent plasma in hospitalized adults
Wesley H Self, Thomas G Stewart, Allison P Wheeler, Wissam El Atrouni, Amanda J Bistran-Hall, Jonathan D Casey, Vince D Cataldo, James D Chappell, Claudia S Cohn, Jessica B Collins, Mark R Denison, Maijolein de Wit, Sheri L Dixon, Abhijit Duggal, Terri L Edwards, Magali J Fontaine, Adit A Ginde, Michelle S Harkins, Thelma Harrington, Estelle S Harris, Daanish Hoda, Tina S Ipe, Stuti J Jaiswal, Nicholas J Johnson, Alan E Jones, Maryrose Laguio-Vila, Christopher J Lindsell, Jason Mallada, Manoj J Mammen, Ryan A Metcalf, Elizabeth A Middleton, Simon Mucha, Hollis R O'Neal, Sonal R Pannu, Jill M Pulley, Xian Qiao, Jay S Raval, Jillian P Rhoads, Harry Schrager, Carl Shanholtz, Nathan I Shapiro, Stephen J Schrantz, Isaac Thomsen, Krista K Vermillion, Gordon R Bernard, Todd W Rice
Research square 2021
Modalities and Mechanisms of Treatment for Coronavirus Disease 2019
Z Zuo, T Wu, L Pan, C Zuo, Y Hu, X Luo, L Jiang, Z Xia, X Xiao, J Liu, M Ye, M Deng
Frontiers in pharmacology 2021
Therapeutic Strategies in the Management of COVID-19
RR Naik, AK Shakya
Frontiers in Molecular Biosciences 2021
Convalescent plasma treatment is associated with lower mortality and better outcomes in high-risk COVID-19 patients – propensity-score matched case-control study
A Tworek, K Jaroń, B Uszyńska-Kałuża, A Rydzewski, R Gil, A Deptała, E Franek, R Wójtowicz, K Życińska, I Walecka, M Cicha, W Wierzba, A Zaczyński, ZJ Król, G Rydzewska
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases 2021
Matched Cohort Study of Convalescent COVID-19 Plasma Treatment in Severely or Life Threateningly Ill COVID-19 Patients
M Klapholz, SR Pentakota, JP Zertuche, M McKenna, W Roque, M Forsberg, J Packer, DS Lal, L Dever
Open Forum Infectious Diseases 2021
Effect of Convalescent Plasma in Critically Ill Patients With COVID-19: An Observational Study
P Kurtz, C Righy, M Gadelha, FA Bozza, PT Bozza, B Gonçalves, LS Bastos, AM Vale, LM Higa, L Castilho, FL Monteiro, N Charris, F Fialho, R Turon, A Guterres, RL Miranda, CH de Azeredo Lima, V de Caro, MA Prazeres, N Ventura, C Gaspari, F Miranda, PJ da Mata, M Pêcego, S Mateos, ME Lopes, S Castilho, Á Oliveira, C Boquimpani, A Rabello, J Lopes, OC Neto, , A Tanuri, PN Filho, L Amorim
Frontiers in Medicine 2021
Selecting COVID ‐19 convalescent plasma for neutralizing antibody potency using a high‐capacity SARS‐CoV ‐2 antibody assay
EG Meyer, G Simmons, E Grebe, M Gannett, S Franz, O Darst, CD Germanio, M Stone, P Contestable, A Prichard, R Reik, R Vassallo, P Young, MP Busch, P Williamson, LJ Dumont
Transfusion 2021
Elevated Rate of HLA Antibodies in Male COVID-19 Convalescent Plasma Donors
JE Juskewitch, JR Stubbs, MJ Gandhi
Mayo Clinic Proceedings 2021
Impact of the COVID‐19 pandemic on blood supply and demand in the WHO African Region
A Loua, OM Kasilo, JB Nikiema, AS Sougou, S Kniazkov, EA Annan
Vox Sanguinis 2021
Correlation between SARS‐COV‐2 antibody screening by immunoassay and neutralizing antibody testing
A MendroneJunior, CL Dinardo, SC Ferreira, A Nishya, NA Salles, CA Neto, DT Hamasaki, T Facincani, LB Alves, RR Machado, DB Araujo, EL Durigon, V Rocha, EC Sabino
Transfusion 2021
Early mortality benefit with COVID‐19 convalescent plasma: a matched control study
AG Shenoy, AZ Hettinger, SJ Fernandez, J Blumenthal, V Baez
British Journal of Haematology 2021
Effect of Bamlanivimab as Monotherapy or in Combination With Etesevimab on Viral Load in Patients With Mild to Moderate COVID-19: A Randomized Clinical Trial
RL Gottlieb, A Nirula, P Chen, J Boscia, B Heller, J Morris, G Huhn, J Cardona, B Mocherla, V Stosor, I Shawa, P Kumar, AC Adams, JV Naarden, KL Custer, M Durante, G Oakley, AE Schade, TR Holzer, PJ Ebert, RE Higgs, NL Kallewaard, J Sabo, DR Patel, P Klekotka, L Shen, DM Skovronsky
Journal of the American Medical Association 2021
COVID-19 Transmission, Current Treatment, and Future Therapeutic Strategies
VS Salian, JA Wright, PT Vedell, S Nair, C Li, M Kandimalla, X Tang, EM Porquera, KR Kalari, KK Kandimalla
Molecular Pharmaceutics 2021
Early High-Titer Plasma Therapy to Prevent Severe Covid-19 in Older Adults
R Libster, GP Marc, D Wappner, S Coviello, A Bianchi, V Braem, I Esteban, MT Caballero, C Wood, M Berrueta, A Rondan, G Lescano, P Cruz, Y Ritou, VF Viña, DÁ Paggi, S Esperante, A Ferreti, G Ofman, Á Ciganda, R Rodriguez, J Lantos, R Valentini, N Itcovici, A Hintze, ML Oyarvide, C Etchegaray, A Neira, I Name, J Alfonso, RL Castelo, G Caruso, S Rapelius, F Alvez, F Etchenique, F Dimase, D Alvarez, SS Aranda, CS Yanotti, JD Luca, SJ Baglivo, S Laudanno, F Nowogrodzki, R Larrea, M Silveyra, G Leberzstein, A Debonis, J Molinos, M González, E Perez, N Kreplak, SusanaArgüello, L Gibbons, F Althabe, E Bergel, FP Polack
New England Journal of Medicine 2021
The role of serum specific- SARS-CoV-2 antibody in COVID-19 patients
H Chen, X Zhang, W Liu, M Xue, C Liao, Z Huang, H Hu, B Sun
International Immunopharmacology 2021
Remdesivir in Coronavirus Disease 2019 (COVID-19) treatment: a review of evidence
HX Lin, S Cho, VM Aravamudan, HY Sanda, R Palraj, JS Molton, I Venkatachalam
Infection 2021
Risk and Management of Venous Thromboembolism in Patients with COVID-19
N Skeik, JE Smith, L Patel, AK Mirza, JM Manunga, D Beddow
Annals of Vascular Surgery 2021
The interplay between inflammatory pathways and COVID-19: A critical review on pathogenesis and therapeutic options
S Choudhary, K Sharma, O Silakari
Microbial Pathogenesis 2021
Controlled trials needed to prove efficacy and safety of convalescent plasma therapy in coronavirus disease 2019
N Hartog, A Holsworth, S Rajasekaran
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 2021
SARS-CoV-2 convalescent plasma therapy in pediatric patient after hematopoietic stem cell transplantation
D Balashov, P Trakhtman, A Livshits, I Kovalenko, G Tereshenko, G Solopova, E Petraikina, A Maschan, G Novichkova
Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis 2021
Antibodies at work in the time of severe acute respiratory syndrome coronavirus 2
KV Sajna, S Kamat
Cytotherapy 2021
Access to and safety of COVID-19 convalescent plasma in the United States Expanded Access Program: A national registry study
JW Senefeld, PW Johnson, KL Kunze, EM Bloch, N van Helmond, MA Golafshar, SA Klassen, AM Klompas, MA Sexton, JC Soto, BJ Grossman, AA Tobian, R Goel, CC Wiggins, KA Bruno, CM van Buskirk, JR Stubbs, JL Winters, A Casadevall, NS Paneth, BH Shaz, MM Petersen, BS Sachais, MR Buras, MA Wieczorek, B Russoniello, LJ Dumont, SE Baker, RR Vassallo, JR Shepherd, PP Young, NC Verdun, P Marks, NR Haley, RF Rea, L Katz, V Herasevich, DA Waxman, ER Whelan, A Bergman, AJ Clayburn, MK Grabowski, KF Larson, JG Ripoll, KJ Andersen, MN Vogt, JJ Dennis, RJ Regimbal, PR Bauer, JE Blair, ZA Buchholtz, MC Pletsch, K Wright, JT Greenshields, MJ Joyner, RS Wright, RE Carter, DL Fairweather, C SoOsman
PLoS Medicine 2021
Outcome of SARS CoV-2 inpatients treated with convalescent plasma: One-year of data from the Veneto region (Italy) Registry
G Silvestro, P Marson, M Raja, A Cattelan, G Guarnieri, J Monticelli, I Tiberio, A Vianello, G Gandini, G Gessoni, F Fiorin, C Sardella, L Astolfi, M Saia
European Journal of Internal Medicine 2021
Perplexing Issues for Convalescent Immune Plasma Therapy in COVID-19
O Ozdemir
Northern Clinics of Istanbul 2021
Efficacy and safety of current treatment interventions for patients with severe COVID‐19 infection: A network meta‐analysis of randomized controlled trials
Q Cheng, G Zhao, J Chen, Q Jia, Z Fang
Journal of Medical Virology 2021
Impact of Convalescent Plasma Therapy on Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Antibody Profile in Coronavirus Disease 2019 (COVID-19) Patients
Tang J, Grubbs G, Lee Y, Golding H, Khurana S
Clinical Infectious Diseases 2021
Blood and blood treatments
Gubler KD, Offner KE, Higham MC, Stephenson LG
Side Effects of Drugs Annual 2021
Effectiveness and Controversy of Convalescent Plasma Therapy for Coronavirus Disease 2019 Patients
Shu Z, Wu P, Qian Q, Zhou L, Du D, Ding M, Peng T, Fang K
2021
Fc-engineered antibody therapeutics with improved anti-SARS-CoV-2 efficacy
Yamin R, Jones AT, Hoffmann HH, Schäfer A, Kao KS, Francis RL, Sheahan TP, Baric RS, Rice CM, Ravetch JV, Bournazos S
Nature 2021
Non-pharmacological treatments for COVID-19: current status and consensus
Pereira AA, de Oliveira Andrade A, de Andrade Palis A, Cabral AM, Barreto CG, de Souza DB, de Paula Silva F, Santos FP, Silva GL, Guimarães JF, de Araújo LA, Nóbrega LR, Mendes LC, Brandão MR, Milagre ST, de Lima Gonçalves V, de Freitas Morales VH, da Conceição Lima V
Research on Biomedical Engineering 2021
Life after COVID-19: Future directions?
Amin P
2021
COVID-19 aus Sicht der Hämatologie und Hämostaseologie
Spiekermann K, Subklewe M, Hildebrandt M, Humpe A, von Bergwelt-Baildon M
2021
Emergency Use of Convalescent Plasma: Perception of the Regulatory Framework from a Clinical Perspective
Möhnle P, Humpe A, Boeck M, Gruetzner S, Hackstein H, Offner R, Hildebrandt M
Transfusion Medicine and Hemotherapy 2021
Severe Acute Respiratory Syndrome Coronavirus 2 Convalescent Plasma Versus Standard Plasma in Coronavirus Disease 2019 Infected Hospitalized Patients in New York: A Double-Blind Randomized Trial
Bennett-Guerrero E, Romeiser JL, Talbot LR, Ahmed T, Mamone LJ, Singh SM, Hearing JC, Salman H, Holiprosad DD, Freedenberg AT, Carter JA, Browne NJ, Cosgrove ME, Shevik ME, Generale LM, Andrew MA, Nachman S, Fries BC
Critical Care Medicine 2021
Clinical characteristics of hospitalised patients with COVID-19 and the impact on mortality: a single-network, retrospective cohort study from Pennsylvania state.
Gadhiya KP, Hansrivijit P, Gangireddy M, Goldman JD
BMJ Open 2021
Functional Antibodies in COVID-19 Convalescent Plasma.
Herman JD, Wang C, Loos C, Yoon H, Rivera J, Dieterle ME, Haslwanter D, Jangra RK, Bortz RH 3rd, Bar KJ, Julg B, Chandran K, Lauffenburger D, Pirofski LA, Alter G
medRxiv : the preprint server for health sciences 2021
Randomized controlled trial transfusing convalescent plasma as post-exposure prophylaxis against SARS-CoV-2 infection.
Shoham S, Bloch EM, Casadevall A, Hanley D, Lau B, Gebo K, Cachay E, Kassaye SG, Paxton JH, Gerber J, Levine AC, Currier J, Patel B, Allen ES, Anjan S, Appel L, Baksh S, Blair PW, Bowen A, Broderick P, Caputo CA, Cluzet V, Cordisco ME, Cruser D, Ehrhardt S, Forthal D, Fukuta Y, Gawad AL, Gniadek T, Hammel J, Huaman MA, Jabs DA, Jedlicka A, Karlen N, Klein S, Laeyendecker O, Lane K, McBee N, Meisenberg B, Merlo C, Mosnaim G, Park HS, Pekosz A, Petrini J, Rausch W, Shade DM, Shapiro JR, Singleton JR, Sutcliffe C, Thomas DL, Yarava A, Zand M, Zenilman JM, Tobian AAR, Sullivan D
medRxiv : the preprint server for health sciences 2021
Randomized Controlled Trial of Early Outpatient COVID-19 Treatment with High-Titer Convalescent Plasma.
Sullivan DJ, Gebo KA, Shoham S, Bloch EM, Lau B, Shenoy AG, Mosnaim GS, Gniadek TJ, Fukuta Y, Patel B, Heath SL, Levine AC, Meisenberg BR, Spivak ES, Anjan S, Huaman MA, Blair JE, Currier JS, Paxton JH, Gerber JM, Petrini JR, Broderick PB, Rausch W, Cordisco ME, Hammel J, Greenblatt B, Cluzet VC, Cruser D, Oei K, Abinante M, Hammitt LL, Sutcliffe CG, Forthal DN, Zand MS, Cachay ER, Raval JS, Kassaye SG, Foster EC, Roth M, Marshall CE, Yarava A, Lane K, McBee NA, Gawad AL, Karlen N, Singh A, Ford DE, Jabs DA, Appel LJ, Shade DM, Ehrhardt S, Baksh SN, Laeyendecker O, Pekosz A, Klein SL, Casadevall A, Tobian AAR, Hanley DF
medRxiv : the preprint server for health sciences 2021
Convalescent Plasma Use in the United States was inversely correlated with COVID-19 Mortality: Did Plasma Hesitancy cost lives?
Casadevall A, Dragotakes Q, Johnson PW, Senefeld JW, Klassen SA, Wright RS, Joyner MJ, Paneth N, Carter RE
2021
COVID-19 antibody development fueled by HIV-1 bNAb research
Mendoza P, Lorenzi JC, Gaebler C
Current opinion in HIV and AIDS 2021
SARS-CoV-2 viral load and antibody responses: the case for convalescent plasma therapy
Arturo Casadevall, Michael J. Joyner, Liise-anne Pirofski
Journal of Clinical Investigation 2020
What are protective antibody responses to pandemic SARS-CoV-2?
Jeffrey P. Henderson
Journal of Clinical Investigation 2020
Sex, age, and hospitalization drive antibody responses in a COVID-19 convalescent plasma donor population
Sabra L. Klein, Andrew Pekosz, Han-Sol Park, Rebecca L. Ursin, Janna R. Shapiro, Sarah E. Benner, Kirsten Littlefield, Swetha Kumar, Harnish Mukesh Naik, Michael Betenbaugh, Ruchee Shrestha, Annie A. Wu, Robert M. Hughes, Imani Burgess, Patrizio Caturegli, Oliver Laeyendecker, Thomas C. Quinn, David J. Sullivan, Shmuel Shoham, Andrew D. Redd, Evan M. Bloch, Arturo Casadevall, Aaron A. R. Tobian
Journal of Clinical Investigation 2020
Autoinflammatory and autoimmune conditions at the crossroad of COVID-19
Y Rodríguez, L Novelli, M Rojas, MD Santis, Y Acosta-Ampudia, DM Monsalve, C Ramírez-Santana, A Costanzo, WM Ridgway, AA Ansari, ME Gershwin, C Selmi, JM Anaya
Journal of Autoimmunity 2020
Neurological injuries in COVID-19 patients: direct viral invasion or a bystander injury after infection of epithelial/endothelial cells
SA Azizi, SA Azizi
Journal of Neurovirology 2020
The role of IgG Fc receptors in antibody-dependent enhancement
S Bournazos, A Gupta, JV Ravetch
Nature Reviews Immunology 2020
Evaluation of Platelet Responses in Transfusion-Related Acute Lung Injury (TRALI)
EA van der Laan, S van der Velden, L Porcelijn, JW Semple, CE van der Schoot, R Kapur
Transfusion Medicine Reviews 2020
Pharmaco-Immunomodulatory Therapy in COVID-19
JG Rizk, K Kalantar-Zadeh, MR Mehra, CJ Lavie, Y Rizk, DN Forthal
Drugs 2020
Understanding the complexities of SARS-CoV2 infection and its immunology: A road to immune-based therapeutics
V Kumar
International Immunopharmacology 2020
Emerging pharmacological therapies for ARDS: COVID-19 and beyond
S Horie, B McNicholas, E Rezoagli, T Pham, G Curley, D McAuley, C OKane, A Nichol, C dos Santos, PR Rocco, G Bellani, JG Laffey
Intensive Care Medicine 2020
Convalescent Plasma against COVID-19: A Broad-Spectrum Therapeutic Approach for Emerging Infectious Diseases
M Thijssen, T Devos, HS Ejtahed, S Amini-Bavil-Olyaee, AA Pourfathollah, MR Pourkarim
Microorganisms 2020
Antibody-dependent enhancement and COVID-19: Moving toward acquittal
EJ Yager
Clinical Immunology 2020
Convalescent plasma to treat critically ill patients with COVID-19: framing the need for randomised clinical trials
M Shankar-Hari, L Estcourt, H Harvala, D Roberts, DK Menon, M Shankar-Hari, L Estcourt, H Harvala, D Roberts, DK Menon
Critical Care 2020
Clinical predictors of donor antibody titre and correlation with recipient antibody response in a COVID‐19 convalescent plasma clinical trial
ML Madariaga, JJ Guthmiller, S Schrantz, MO Jansen, C Christensen, M Kumar, M Prochaska, G Wool, A DurkinCelauro, WH Oh, L Trockman, J Vigneswaran, R Keskey, DG Shaw, H Dugan, NY Zheng, M Cobb, H Utset, J Wang, O Stovicek, C Bethel, S Matushek, M Giurcanu, KG Beavis, D Sabato, D Meltzer, MK Ferguson, JP Kress, K Shanmugarajah, JB Matthews, JF Fung, PC Wilson, JC Alverdy, JS Donington
Journal of Internal Medicine 2020
A Retrospective Study on the Effects of Convalescent Plasma Therapy in 24 Patients Diagnosed with COVID-19 Pneumonia in February and March 2020 at 2 Centers in Wuhan, China
S Huang, C Shen, C Xia, X Huang, Y Fu, L Tian
Medical science monitor : international medical journal of experimental and clinical research 2020

Convalescent Plasma Therapy for Management of COVID-19: Perspectives and Deployment in the Current Global Pandemic


N Samad, TE Sodunke, HA Banna, A Sapkota, AN Fatema, K Iskandar, D Jahan, TC Hardcastle, T Nusrat, TS Chowdhury, M Haque
Risk Management and Healthcare Policy 2020
Safety Update
MJ Joyner, KA Bruno, SA Klassen, KL Kunze, PW Johnson, ER Lesser, CC Wiggins, JW Senefeld, AM Klompas, DO Hodge, JR Shepherd, RF Rea, ER Whelan, AJ Clayburn, MR Spiegel, SE Baker, KF Larson, JG Ripoll, KJ Andersen, MR Buras, MN Vogt, V Herasevich, JJ Dennis, RJ Regimbal, PR Bauer, JE Blair, CM van Buskirk, JL Winters, JR Stubbs, N van Helmond, BP Butterfield, MA Sexton, JC Soto, NS Paneth, NC Verdun, P Marks, A Casadevall, DL Fairweather, RE Carter, RS Wright
Mayo Clinic Proceedings 2020
SARS-CoV-2 Antibody Avidity Responses in COVID-19 Patients and Convalescent Plasma Donors
SE Benner, EU Patel, O Laeyendecker, A Pekosz, K Littlefield, Y Eby, RE Fernandez, J Miller, CS Kirby, M Keruly, E Klock, OR Baker, HA Schmidt, R Shrestha, I Burgess, TS Bonny, W Clarke, P Caturegli, D Sullivan, S Shoham, TC Quinn, EM Bloch, A Casadevall, AA Tobian, AD Redd
The Journal of Infectious Diseases 2020
Convalescent plasma for pediatric patients with SARS‐CoV‐2‐associated acute respiratory distress syndrome
C Diorio, EM Anderson, KO McNerney, EC Goodwin, JC Chase, MJ Bolton, CP Arevalo, ME Weirick, S Gouma, LA Vella, SE Henrickson, K Chiotos, JC Fitzgerald, TJ Kilbaugh, AR John, AM Blatz, MP Lambert, KE Sullivan, MR Tartaglione, D Zambrano, M Martin, JH Lee, P Young, D Friedman, DA SesokPizzini, SE Hensley, EM Behrens, H Bassiri, DT Teachey
Pediatric Blood & Cancer 2020
Convalescent Plasma in the Treatment of Severe COVID-19: A Systematic Review and Meta-Analysis
X ZHANG, , F PANG, Y DU, Q YUAN, M SHI, J LIU, H MA, B LI
2020
Mortality reduction in 46 severe Covid-19 patients treated with hyperimmune plasma. A proof of concept single arm multicenter trial
C Perotti, F Baldanti, R Bruno, CD Fante, E Seminari, S Casari, E Percivalle, C Glingani, V Musella, M Belliato, M Garuti, F Meloni, M Frigato, AD Sabatino, C Klersy, GD Donno, M Franchini, C plasma task force
Haematologica 2020
Convalescent plasma for administration of passive antibodies against viral agents
GD Minno, PM Mannucci, JW Ironside, CF Perno, L Gürtler, L Aledort
Haematologica 2020
Recruitment Strategy for Potential COVID-19 Convalescent Plasma Donors
KJ Andersen, SA Klassen, KF Larson, JG Ripoll, JW Senefeld, AJ Clayburn, JR Shepherd, AS Tseng, CC Wiggins, BM Murphy, SK Ford, CP Johnson, AD Miller, SE Baker, RS Wright, JL Winters, JR Stubbs, MJ Joyner, CM van Buskirk
Mayo Clinic Proceedings 2020
Emerging treatment strategies for COVID-19 infection
M Gavriatopoulou, I Ntanasis-Stathopoulos, E Korompoki, D Fotiou, M Migkou, IG Tzanninis, T Psaltopoulou, E Kastritis, E Terpos, MA Dimopoulos
Clinical and Experimental Medicine 2020
Antibody Binding to SARS-CoV-2 S Glycoprotein Correlates with but Does Not Predict Neutralization
S Ding, A Laumaea, M Benlarbi, G Beaudoin-Bussières, R Gasser, H Medjahed, M Pancera, L Stamatatos, A McGuire, R Bazin, A Finzi
Viruses 2020
A single center cohort of 40 severe COVID-19 patients who were treated with convalescent plasma
A GEMİCİ, H BİLGEN, C ERDOĞAN, A KANSU, O OLMUŞÇELİK, HS BEKÖZ, R DİNLEYİCİ, A MERT, ÖG SEVİNDİK
2020
Decline of Humoral Responses against SARS-CoV-2 Spike in Convalescent Individuals
G Beaudoin-Bussières, A Laumaea, SP Anand, J Prévost, R Gasser, G Goyette, H Medjahed, J Perreault, T Tremblay, A Lewin, L Gokool, C Morrisseau, P Bégin, C Tremblay, V Martel-Laferrière, DE Kaufmann, J Richard, R Bazin, A Finzi, DD Ho, SP Goff
mBio 2020
Convalescent plasma appears efficacious and safe in COVID-19
D Khulood, MS Adil, R Sultana, Nimra
Therapeutic advances in infectious disease 2020
Three patients with X-linked agammaglobulinemia hospitalized for COVID-19 improved with convalescent plasma
H Jin, JC Reed, ST Liu, H Ho, JP Lopes, NB Ramsey, O Waqar, F Rahman, JA Aberg, NM Bouvier, C Cunningham-Rundles, ST Liu, HM Lin, A Abrams-Downey, KP Cascetta, AE Glatt, SC Koshy, E Kojic, DS Mazo, D Perlman, S Rudolph, J Steinberg, T Schneider, I Baine, A Wajnberg, JP Gumprecht, F Rahman, D Rodriguez, C Sanky, A Dupper, DR Altman, F Krammer, DR Mendu, A Firpo-Betancourt, C Cordon-Cardo, JS Jhang, SA Arinsberg, DL Reich, JA Aberg, NM Bouvier
The Journal of Allergy and Clinical Immunology: In Practice 2020
Treatment of COVID-19 with convalescent plasma: lessons from past coronavirus outbreaks
DJ Wooding, H Bach
Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 2020
Convalescent serum therapy for COVID-19: A 19th century remedy for a 21st century disease
D Montelongo-Jauregui, T Vila, AS Sultan, MA Jabra-Rizk, RE Dutch
PLoS pathogens 2020
Earlier the better: convalescent plasma
AA Tobian, BH Shaz
Blood 2020
International Survey of Trials of Convalescent Plasma to Treat COVID-19 Infection
M Murphy, L Estcourt, J Grant-Casey, S Dzik
Transfusion Medicine Reviews 2020
Clinical efficacy of convalescent plasma for treatment of COVID-19 infections: Results of a multicenter clinical study
H Abolghasemi, P Eshghi, AM Cheraghali, AA Fooladi, FB Moghaddam, S Imanizadeh, MM Maleki, M Ranjkesh, M Rezapour, A Bahramifar, B Einollahi, MJ Hosseini, NJ Jafari, M Nikpouraghdam, N Sadri, M Tazik, S Sali, S Okati, E Askari, P Tabarsi, J Aslani, E Sharifipour, MH Jarahzadeh, N Khodakarim, M Salesi, R Jafari, S Shahverdi
Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis 2020
Convalescent plasma or hyperimmune immunoglobulin for people with COVID-19: a living systematic review
V Piechotta, KL Chai, SJ Valk, C Doree, I Monsef, EM Wood, A Lamikanra, C Kimber, Z McQuilten, C So-Osman, LJ Estcourt, N Skoetz
Cochrane Database of Systematic Reviews 2020
Transfusion Service Response to the COVID-19 Pandemic
E Gehrie, CA Tormey, KW Sanford
American Journal of Clinical Pathology 2020
Improved clinical symptoms and mortality among patients with severe or critical COVID-19 after convalescent plasma transfusion
X Xia, K Li, L Wu, Z Wang, M Zhu, B Huang, J Li, Z Wang, W Wu, M Wu, W Li, L Li, Y Cai, B Bosco, A Zhong, X Liu, T Lv, Z Gan, G Chen, Y Pan, C Liu, K Zhang, X Xu, C Wang, Q Wang
Blood 2020
Clinical use of Convalescent Plasma in the COVID‐19 pandemic: a transfusion‐focussed gap analysis with recommendations for future research priorities
AZ AlRiyami, R Schäfer, K Berg, EM Bloch, LJ Estcourt, R Goel, S Hindawi, CD Josephson, K Land, ZK McQuilten, SL Spitalnik, EM Wood, DV Devine, C SoOsman
Vox Sanguinis 2020

A Review on Currently Available Potential Therapeutic Options for COVID-19


SO Moghadam
International journal of general medicine 2020
Host-pathogen interaction in COVID-19: Pathogenesis, potential therapeutics and vaccination strategies
PM Varghese, AG Tsolaki, H Yasmin, A Shastri, J Ferluga, M Vatish, T Madan, U Kishore
Immunobiology 2020
COVID-19 treatments and pathogenesis including anosmia in K18-hACE2 mice
J Zheng, LY Wong, K Li, AK Verma, ME Ortiz, C Wohlford-Lenane, MR Leidinger, CM Knudson, DK Meyerholz, PB McCray, S Perlman
Nature 2020
The Assessment of Convalescent Plasma Efficacy against COVID-19
A Casadevall, BJ Grossman, JP Henderson, MJ Joyner, S Shoham, L Pirofski, N Paneth
The American Journal of Medicine 2020
COVID-19 Therapeutic Options Under Investigation
M Kaddoura, M AlIbrahim, G Hijazi, N Soudani, A Audi, H Alkalamouni, S Haddad, A Eid, H Zaraket
Frontiers in pharmacology 2020
Convalescent Plasma Therapy for COVID-19: State of the Art
D Focosi, AO Anderson, JW Tang, M Tuccori
Clinical microbiology reviews 2020
Neutralizing antibodies against SARS-CoV-2: current understanding, challenge and perspective
Y Huang, H Sun, H Yu, S Li, Q Zheng, N Xia
2020
A retrospective study assessing the characteristics of COVID‐19 convalescent plasma donors and donations
CD Fante, M Franchini, F Baldanti, E Percivalle, C Glingani, G Marano, C Mengoli, C Mortellaro, G Viarengo, C Perotti, GM Liumbruno
Transfusion 2020
Skin and gastrointestinal symptoms in COVID-19
P Ciechanowicz, K Lewandowski, E Szymańska, M Kaniewska, G Rydzewska, I Walecka
PRZ GASTROENTEROL 2020
Pragmatic Recommendations for Therapeutics of Hospitalized COVID-19 Patients in Low- and Middle-Income Countries
VU Shetty, BJ Brotherton, A Achilleos, KM Akrami, LM Barros, W Checkley, N Cobb, S Maximous, D Misango, C Park, S Taran, BW Lee
The American journal of tropical medicine and hygiene 2020
Convalescent Plasma Transfusion for the Treatment of COVID-19—Experience from Poland: A Multicenter Study
A Moniuszko-Malinowska, P Czupryna, D Zarębska-Michaluk, K Tomasiewicz, S Pancewicz, M Rorat, A Dworzańska, K Sikorska, B Bolewska, B Lorenc, A Chciałowski, D Kozielewicz, B Oczko-Grzesik, A Szymanek-Pasternak, B Szetela, M Figlerowicz, M Rogalska, I Zaleska, R Flisiak
Journal of Clinical Medicine 2020
A Review of Treatment of Coronavirus Disease 2019 (COVID-19): Therapeutic Repurposing and Unmet Clinical Needs
PL Chen, NY Lee, CT Cia, WC Ko, PR Hsueh
Frontiers in pharmacology 2020
COVID-19 Treatment at a Glance
H Arikan, D Karadogan, FT Akyil, A Yuksel, ZN Toreyin, CG Gurkan, F Marim, TS Eyuboglu, N Emiralioglu, TR Gursoy, I Serifoglu, A Sandal, A Oncel, B Er, N Kose, D Esendagli, M Hizal, AB Er, FE Gunaydin, I Kaya, H Ozakinci, UO Sertcelik, HC Tuglu, NA Ozurk, O Ataoglu, AC Cakir, H Toptay, M Ercelik, E Develi, S Celik, FG Karakas, H Yildirim, DK Guven, N Cetin, SN Kucukyurt, MF Elverisli, PY Gulhan, M Akgun
2020
Safety and efficacy of convalescent plasma therapy in severely and critically ill patients with COVID-19: a systematic review with meta-analysis
L Wenjing, F Yuanzheng, JY Li, LV Tang, H Yu
Aging 2020
A multicenter randomized trial to assess the efficacy of CONvalescent plasma therapy in patients with Invasive COVID-19 and acute respiratory failure treated with mechanical ventilation: the CONFIDENT trial protocol
B Misset, E Hoste, AF Donneau, D Grimaldi, G Meyfroidt, M Moutschen, V Compernolle, A Gothot, D Desmecht, M Garigliany, T Najdovski, PF Laterre
BMC Pulmonary Medicine 2020
A randomized, multicentre, open-label phase II proof-of-concept trial investigating the clinical efficacy and safety of the addition of convalescent plasma to the standard of care in patients hospitalized with COVID-19: the Donated Antibodies Working against nCoV (DAWn-Plasma) trial
T Devos, T Geukens, A Schauwvlieghe, KK Ariën, C Barbezange, M Cleeren, V Compernolle, N Dauby, D Desmecht, D Grimaldi, BN Lambrecht, A Luyten, P Maes, M Moutschen, M Romano, L Seyler, MT Nevessignsky, K Vandenberghe, J van Griensven, G Verbeke, E Vlieghe, JC Yombi, L Liesenborghs, P Verhamme, G Meyfroidt
Trials 2020
A serological assay to detect SARS-CoV-2 antibodies in at-home collected finger-prick dried blood spots
DG Karp, K Danh, NF Espinoza, D Seftel, PV Robinson, C Tsai
Scientific Reports 2020
Medical management of COVID-19 clinic
N Mehta, R Qiao
Journal of Biomedical Research 2020
Cyanoamidine Cyclization Approach to Remdesivir’s Nucleobase
RR Knapp, V Tona, T Okada, R Sarpong, NK Garg
Organic letters 2020
Pulmonary surfactant: an immunological perspective
ZC Chroneos, Z Sever-Chroneos, VL Shepherd
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2009
Abnormal antibodies to self-carbohydrates in SARS-CoV-2 infected patients
Dorothy L Butler, Jeffrey C Gildersleeve
Convalescent plasma therapy in patients with COVID-19
F Altuntas, N Ata, TN Yigenoglu, S Bascı, MS Dal, S Korkmaz, S Namdaroglu, A Basturk, T Hacıbekiroglu, MH Dogu, İ Berber, K Dal, K Kınık, İ Haznedaroglu, FM Yılmaz, İ Kılıç, S Demircioğlu, A Yosunkaya, MA Erkurt, B Turgut, M Caglayan, O Celik
Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis 2021
Identification and Tracking of Antiviral Drug Combinations
A Ianevski, R Yao, S Biza, E Zusinaite, A Mannik, G Kivi, A Planken, K Kurg, EM Tombak, M Ustav, N Shtaida, E Kulesskiy, E Jo, J Yang, H Lysvand, K Løseth, V Oksenych, PA Aas, T Tenson, A Vitkauskienė, MP Windisch, MH Fenstad, SA Nordbø, M Ustav, M Bjørås, DE Kainov
Viruses 2020
Evidence-based management of COVID-19 in cancer patients: Guideline by the Infectious Diseases Working Party (AGIHO) of the German Society for Haematology and Medical Oncology (DGHO)
N Giesen, R Sprute, M Rüthrich, Y Khodamoradi, SC Mellinghoff, G Beutel, C Lueck, M Koldehoff, M Hentrich, M Sandherr, M von Bergwelt-Baildon, HH Wolf, HH Hirsch, B Wörmann, OA Cornely, P Köhler, E Schalk, M von Lilienfeld-Toal
European Journal of Cancer 2020
Convalescent Plasma Therapy in Four Critically Ill Pediatric Patients With Coronavirus Disease 2019: A Case Series
SP Schwartz, P Thompson, M Smith, DM Lercher, CA Rimland, L Bartelt, YA Park, S Weiss, AJ Markmann, R Raut, L Premkumar, JA Kuruc, Z Willis
2020
Convalescent Plasma Therapy for Coronavirus Disease 2019
JY Choi
Infection & Chemotherapy 2020
Vitamin D sufficiency, a serum 25-hydroxyvitamin D at least 30 ng/mL reduced risk for adverse clinical outcomes in patients with COVID-19 infection
Z Maghbooli, MA Sahraian, M Ebrahimi, M Pazoki, S Kafan, HM Tabriz, A Hadadi, M Montazeri, M Nasiri, A Shirvani, MF Holick, M Adrish
PloS one 2020
The use of mesenchymal stromal cells in the treatment of coronavirus disease 2019
MA Canham, JD Campbell, JC Mountford
Journal of Translational Medicine 2020
Factors Associated with Good Patient Outcomes Following Convalescent Plasma in COVID-19: A Prospective Phase II Clinical Trial
D Ibrahim, L Dulipsingh, L Zapatka, R Eadie, R Crowell, K Williams, DB Wakefield, L Cook, J Puff, SA Hussain
Infectious Diseases and Therapy 2020
Convalescent Plasma for the Treatment of Severe COVID‐19 Infection in Cancer Patients
D Tremblay, C Seah, T Schneider, S Bhalla, J Feld, L Naymagon, B Wang, V Patel, T Jun, T Jandl, F Rahman, ST Liu, JA Aberg, N Bouvier
Cancer Medicine 2020
Screening for SARS‐CoV ‐2 antibodies in convalescent plasma in Brazil: Preliminary lessons from a voluntary convalescent donor program
S Wendel, JM Kutner, R Machado, R FontãoWendel, C Bub, R Fachini, A Yokoyama, G Candelaria, A Sakashita, R Achkar, N Hamerschlak, P Scuracchio, M Amaral, MD Ben, D Araujo, C Soares, A Camargo, E Kallás, E Durigon, LF Reis, LV Rizzo
Transfusion 2020
Probiotics and Coronavirus disease 2019: think about the link
SK Angurana, A Bansal
British Journal of Nutrition 2020
COVID-19: FAQs in Pediatric Cardiac Surgery—A Sequel
E Levy, J Blumenthal, K Chiotos, EH Stephens, JA Dearani
World journal for pediatric &#x0026; congenital heart surgery 2020
A Review on Current Repurposing Drugs for the Treatment of COVID-19: Reality and Challenges
S Hossen, A Barek, N Jahan, MS Islam
2020
Convalescent plasma as a treatment modality for coronavirus disease 2019 in Sudan
MO Hassan, AA Osman, HE Elbasit, HE Hassan, H Rufai, MM Satti, M Elnegoumi, R Idris, A Musa, AH Ali, SA Zroog, AD Altayb, A Khairy, M Allam, AT Abdelhalim
Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis 2020
Convalescent plasma therapy for coronavirus infection: experience from MERS and application in COVID-19
JA Al-Tawfiq, Y Arabi
Human Vaccines & Immunotherapeutics 2020
Challenges in the Management of Sickle Cell Disease During SARS-CoV-2 Pandemic
F Alsayegh, SA Mousa
Clinical and Applied Thrombosis/Hemostasis 2020
Convalescent plasma for COVID-19: the risk of pulmonary embolism should not be underestimated!
F Sanfilippo, VL Rosa, F Oliveri, M Astuto
Critical Care 2020
Treatment of Coronavirus Disease 2019 Patients with Convalescent Plasma Reveals a Signal of Significantly Decreased Mortality
E Salazar, PA Christensen, EA Graviss, DT Nguyen, B Castillo, J Chen, BV Lopez, TN Eagar, X Yi, P Zhao, J Rogers, A Shehabeldin, D Joseph, C Leveque, RJ Olsen, DW Bernard, J Gollihar, JM Musser
The American Journal of Pathology 2020
Hospitalized COVID-19 Patients Treated With Convalescent Plasma in a Mid-size City in The Mid West
William R Hartman, Aaron S Hess, Joseph P Connor
Research square 2020
Rethinking Gain-of-Function Experiments in the Context of the COVID-19 Pandemic
MJ Imperiale, A Casadevall
mBio 2020
Immunotherapy for SARS-CoV-2: potential opportunities
M Pashaei, N Rezaei
Expert Opinion on Biological Therapy 2020
Guidelines for COVID-19 Management in Hematopoietic Cell Transplantation and Cellular Therapy Recipients
A Waghmare, MZ Abidi, M Boeckh, RF Chemaly, S Dadwal, ZE Boghdadly, M Kamboj, GA Papanicolaou, SA Pergam, Z Shahid
Biology of Blood and Marrow Transplantation 2020
Hospitalized COVID-19 Patients treated with Convalescent Plasma in a Mid-size City in the Midwest
William R Hartman, Aaron S Hess, Joseph P Connor
Research square 2020
Passive immunotherapy with convalescent plasma against COVID-19? What about the evidence base and clinical trials?
O Garraud
Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis 2020
Therapeutic plasma exchange in adults with severe COVID-19 infection
F Khamis, I Al-Zakwani, SA Hashmi, SA Dowaiki, MA Bahrani, N Pandak, HA Khalili, Z Memish
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases 2020
Investigational Therapies for the Treatment of COVID-19: Updates from Ongoing Clinical Trials
A Abrams-Downey, J Saabiye, M Vidaurrazaga
European Urology Focus 2020
Use of convalescent plasma in hospitalized patients with COVID-19: case series
L Hegerova, TA Gooley, KA Sweerus, C Maree, N Bailey, M Bailey, V Dunleavy, K Patel, K Alcorn, R Haley, JM Johnsen, BA Konkle, AC Lahti, ML Alexander, JD Goldman, A Lipke, S Lim, MD Sullivan, JS Pauk, JM Pagel
Blood 2020
Convalescent plasma – this is no time for competition
A Farrugia, J MacPherson, MP Busch
Transfusion 2020
A Narrative Review of Emerging Therapeutics for COVID-19
Willis VC, Arriaga Y, Weeraratne D, Reyes F, Jackson GP
2020
Rekonvaleszentenplasma zur Behandlung von schwerem COVID-19: Rationale und Design einer randomisierten, offenen klinischen Studie von Rekonvaleszentenplasma verglichen mit bestmöglicher supportiver Behandlung (CAPSID-Studie)
Körper S, Jahrsdörfer B, Appl T, Klüter H, Seifried E, Schrezenmeier H
2020
COVID-19 convalescent plasma treatment of moderate and severe cases of SARS-CoV-2 infection: A multicenter interventional study
Alsharidah S, Ayed M, Ameen RM, Alhuraish F, Rouheldeen NA, Alshammari FR, Embaireeg A, Almelahi M, Adel M, Dawoud ME, Aljasmi MA, Alshammari N, Alsaeedi A, Al-Adsani W, Arian H, Awad H, Alenezi HA, Alzafiri A, Gouda EF, Almehanna M, Alqahtani S, Alshammari A, Askar MZ
International Journal of Infectious Diseases 2020
Actualización de la Declaración de consenso en medicina critica para la atención multidisciplinaria del paciente con sospecha o confirmación diagnóstica de COVID-19
Accini Mendoza JL, Nieto Estrada VH, Beltrán López N, Ramos Bolaños E, Molano Franco D, Dueñas Castell C, Valencia Moreno AA, Alarcón Amaya IC, Serna Flórez J, Gil Valencia BA, Pizarro C, Zabaleta Polo YM, Chica Meza CL
Acta Colombiana de Cuidado Intensivo 2020
Anti-SARS-CoV-2 spike antibodies are stable in convalescent plasma when stored at 4° Celsius for at least 6 weeks.
Stadlbauer D, Baine I, Amanat F, Jiang K, Lally K, Krammer F, Jhang JS, Arinsburg SA
Transfusion 2020
Convalescent plasma for COVID‐19: Back to the future
Roberts DJ, Miflin G, Estcourt L
Transfusion Medicine 2020
Guidance for the procurement of COVID‐19 convalescent plasma: differences between high‐ and low‐middle‐income countries
Bloch EM, Goel R, Wendel S, Burnouf T, Al\u2010Riyami AZ, Ang AL, DeAngelis V, Dumont LJ, Land K, Lee C, Oreh A, Patidar G, Spitalnik SL, Vermeulen M, Hindawi S, Van den Berg K, Tiberghien P, Vrielink H, Young P, Devine D, So \u2013 Osman C
Vox Sanguinis 2020
Convalescent plasma is a clutch at straws in COVID‐19 management! A systematic review and meta‐analysis
Sarkar S, Soni KD, Khanna P
Journal of Medical Virology 2020
Supply and demand for plasma‐derived medicinal products ‐ A critical reassessment amid the COVID‐19 pandemic
Hartmann J, Klein HG
Transfusion 2020
A consideration of convalescent plasma and plasma derivatives in the care of Severely-ill patients with COVID-19.
Lung T, Kazatchkine MD, Risch L, Risch M, Nydegger UE
Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis 2020
Treatment of Severe COVID-19 with Convalescent Plasma in the Bronx, NYC.
Yoon HA, Bartash R, Gendlina I, Rivera J, Nakouzi A, Bortz RH 3rd, Wirchnianski AS, Paroder M, Fehn K, Serrano-Rahman L, Babb R, Sarwar UN, Haslwanter D, Laudermilch E, Florez C, Dieterle ME, Jangra RK, Fels JM, Tong K, Mariano MC, Vergnolle O, Georgiev GI, Herrera NG, Malonis RJ, Quiroz JA, Morano NC, Krause GJ, Sweeney JM, Cowman K, Allen S, Annam J, Applebaum A, Barboto D, Khokhar A, Lally BJ, Lee A, Lee M, Malaviya A, Sample R, Yang XA, Li Y, Ruiz R, Thota R, Barnhill J, Goldstein DY, Uehlinger J, Garforth SJ, Almo SC, Lai JR, Gil MR, Fox AS, Chandran K, Wang T, Daily JP, Pirofski LA
medRxiv : the preprint server for health sciences 2020
A SARS-CoV-2 serological assay to determine the presence of blocking antibodies that compete for human ACE2 binding.
Byrnes JR, Zhou XX, Lui I, Elledge SK, Glasgow JE, Lim SA, Loudermilk R, Chiu CY, Wilson MR, Leung KK, Wells JA
medRxiv : the preprint server for health sciences 2020
Comparative performance of five commercially available serologic assays to detect antibodies to SARS-CoV-2 and identify individuals with high neutralizing titers.
Patel EU, Bloch EM, Clarke W, Hsieh YH, Boon D, Eby Y, Fernandez RE, Baker OR, Keruly M, Kirby CS, Klock E, Littlefield K, Miller J, Schmidt HA, Sullivan P, Piwowar-Manning E, Shrestha R, Redd AD, Rothman RE, Sullivan D, Shoham S, Casadevall A, Quinn TC, Pekosz A, Tobian AAR, Laeyendecker O
medRxiv : the preprint server for health sciences 2020
Abnormal antibodies to self-carbohydrates in SARS-CoV-2 infected patients.
Butler DL, Gildersleeve JC
bioRxiv : the preprint server for biology 2020
Quantifying absolute neutralization titers against SARS-CoV-2 by a standardized virus neutralization assay allows for cross-cohort comparisons of COVID-19 sera
Oguntuyo KY, Stevens CS, Hung CT, Ikegame S, Acklin JA, Kowdle SS, Carmichael JC, Chiu HP, Azarm KD, Haas GD, Amanat F, Klingler J, Baine I, Arinsburg S, Bandres JC, Siddiquey MN, Schilke RM, Woolard MD, Zhang H, Duty AJ, Kraus TA, Moran TM, Tortorella D, Lim JK, Gamarnik AV, Hioe CE, Zolla-Pazner S, Ivanov SS, Kamil JP, Krammer F, Lee B
2020
A patient affected by critical COVID-19 pneumonia, successfully treated with convalescent plasma
Einollahi B, Cegolon L, Abolghasemi H, Imanizadeh S, Bahramifar A, Zhao S, Jafari R, Javanbakht M
Transfusion and Apheresis Science 2020

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