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N M Wolfman, … , J M Wozney, V Rosen
Published July 15, 1997
Citation Information: J Clin Invest. 1997;100(2):321-330. https://doi.org/10.1172/JCI119537.
Citation Information: J Clin Invest. 1997;100(2):321-330. https://doi.org/10.1172/JCI119537.
Abstract
Research Article
Authors
N M Wolfman, G Hattersley, K Cox, A J Celeste, R Nelson, N Yamaji, J L Dube, E DiBlasio-Smith, J Nove, J J Song, J M Wozney, V Rosen
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Citations to this article (453)
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Local rhBMP-12 on an Absorbable Collagen Sponge as an Adjuvant Therapy for Rotator Cuff Repair— A Phase 1, Randomized, Standard of Care Control, Multicenter Study: Safety and Feasibility
S Greiner, J Ide, AV Noort, Y Mochizuki, H Ochi, S Marraffino, S Sridharan, S Rudicel, E Itoi |
The American journal of sports medicine | 2015 |
|
Posterior Cruciate Ligament Injuries
GC Fanelli |
2015 | |
|
Cellular therapy in bone-tendon interface regeneration
BB Rothrauff, RS Tuan |
Organogenesis | 2014 |
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Biologics for tendon repair
D Docheva, SA Müller, M Majewski, CH Evans |
Advanced Drug Delivery Reviews | 2014 |
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Leri’s pleonosteosis, a congenital rheumatic disease, results from microduplication at 8q22.1 encompassing GDF6 and SDC2 and provides insight into systemic sclerosis pathogenesis
S Banka, SA Cain, S Carim, SB Daly, JE Urquhart, G Erdem, J Harris, M Bottomley, D Donnai, B Kerr, H Kingston, A Superti-Furga, S Unger, H Ennis, J Worthington, AL Herrick, CL Merry, WW Yue, CM Kielty, WG Newman |
Annals of the rheumatic diseases | 2014 |
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The past, present and future in scaffold-based tendon treatments
AJ Lomas, CN Ryan, A Sorushanova, N Shologu, AI Sideri, V Tsioli, GC Fthenakis, A Tzora, I Skoufos, LR Quinlan, G O'Laighin, AM Mullen, JL Kelly, S Kearns, M Biggs, A Pandit, DI Zeugolis |
Advanced Drug Delivery Reviews | 2014 |
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Transcription factor Mohawk controls tenogenic differentiation of bone marrow mesenchymal stem cells in vitro and in vivo: THE TRANSCRIPTION FACTOR MOHAWK CONTROLS TENOGENIC
K Otabe, H Nakahara, A Hasegawa, T Matsukawa, F Ayabe, N Onizuka, M Inui, S Takada, Y Ito, I Sekiya, T Muneta, M Lotz, H Asahara |
Journal of Orthopaedic Research | 2014 |
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Tendon proper- and peritenon-derived progenitor cells have unique tenogenic properties
MJ Mienaltowski, SM Adams, DE Birk |
Stem Cell Research & Therapy | 2014 |
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Immunophenotypic characterization and tenogenic differentiation of mesenchymal stromal cells isolated from equine umbilical cord blood
N Mohanty, BR Gulati, R Kumar, S Gera, P Kumar, RK Somasundaram, S Kumar |
In vitro cellular & developmental biology. Animal | 2014 |
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Biochemical Characterization of Early Osteoarthritis in the Ankle
H Schmal, GM Salzmann, ER Langenmair, R Henkelmann, NP Südkamp, P Niemeyer |
The Scientific World JOURNAL | 2014 |
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BMPRIA Mediated Signaling Is Essential for Temporomandibular Joint Development in Mice
S Gu, W Wu, C Liu, L Yang, C Sun, W Ye, X Li, J Chen, F Long, YP Chen, S Shi |
PloS one | 2014 |
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Roles of bone morphogenetic protein signaling in osteosarcoma
A Nguyen, MA Scott, SM Dry, AW James |
International Orthopaedics | 2014 |
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Preferential tendon stem cell response to growth factor supplementation: Growth factor supplementation of tendon stem cell culture
C Holladay, SA Abbah, C O'Dowd, A Pandit, DI Zeugolis |
Journal of Tissue Engineering and Regenerative Medicine | 2014 |
|
DIFFERENCES BETWEEN PROTEIN EXPRESSION AND EXTRACELLULAR MATRIX STATE ON UNIAXIAL STRETCHING FOR TENOGENIC DIFFERENTIATION
Y Morita, S Suzuki, Y Ju, N Kawase |
Journal of Mechanics in Medicine and Biology | 2014 |
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Cartilage derived morphogenetic protein 2 – A potential therapy for intervertebral disc regeneration?
LA Williams, A Wei, D Bhargav, AD Diwan |
Biologicals | 2014 |
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Ligand- and Stage-Dependent Divergent Functions of BMP Signaling in the Differentiation of Embryonic Skeletogenic Progenitors In Vitro: BMP SIGNALING AND EMBRYONIC SKELETOGENIC DIFFERENTIATION
CI Lorda-Diez, JA Montero, S Choe, JA Garcia-Porrero, JM Hurle |
Journal of Bone and Mineral Research | 2014 |
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Integrin signaling in skeletal development and function: Integrin Signaling in Skeletal Development and Function
D Docheva, C Popov, P Alberton, A Aszodi |
Birth Defects Research Part C Embryo Today Reviews | 2014 |
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Divergent Differentiation of Skeletal Progenitors into Cartilage and Tendon: Lessons from the Embryonic Limb
CI Lorda-Diez, JA Montero, JA Garcia-Porrero, JM Hurle |
ACS chemical biology | 2014 |
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Growth/differentiation factor-5: pre-clinical and clinical evaluations of periodontal regeneration and alveolar augmentation - review
J Lee, UM Wikesjö |
Journal of Clinical Periodontology | 2014 |
|
Association of rs6982567 near GDF6 with neovascular age-related macular degeneration and polypoidal choroidal vasculopathy in a Han Chinese cohort
Y Ji, X Zhang, K Wu, Y Su, M Li, C Zuo, F Wen |
BMC ophthalmology | 2014 |
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Tenomodulin regulated the compartments of embryonic and early postnatal mouse masseter muscle
I Sato, Y Miwa, S Hara, Y Fukuyama, M Sunohara |
Annals of Anatomy - Anatomischer Anzeiger | 2014 |
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Repair of Achilles tendon defect with autologous ASCs engineered tendon in a rabbit model
D Deng, W Wang, B Wang, P Zhang, G Zhou, WJ Zhang, Y Cao, W Liu |
Biomaterials | 2014 |
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Tendon to bone healing and its implications for surgery
Daniel Lee John Bunker, Victor Ilie, Vladimir Ilie, Sean Nicklin |
Muscles, ligaments and tendons journal | 2014 |
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Pentadecapeptide BPC 157 Enhances the Growth Hormone Receptor Expression in Tendon Fibroblasts
CH Chang, WC Tsai, YH Hsu, JH Pang |
Molecules (Basel, Switzerland) | 2014 |
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Freeze-dried allograft-mediated gene or protein delivery of growth and differentiation factor 5 reduces reconstructed murine flexor tendon adhesions
S Hasslund, T Dadali, M Ulrich-Vinther, K Søballe, EM Schwarz, HA Awad |
Journal of Tissue Engineering | 2014 |
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Massive Rotator Cuff Tears
LV Gulotta, EV Craig |
2014 | |
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Cellular distribution and gene expression profile during flexor tendon graft repair: A novel tissue engineering approach(*)
SC Juneja |
Journal of Tissue Engineering | 2013 |
|
Regenerative therapy and tissue engineering for the treatment of end-stage cardiac failure: new developments and challenges
GT Finosh, M Jayabalan |
Biomatter | 2013 |
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Human iPSC-derived Neural Crest Stem Cells Promote Tendon Repair in a Rat Patellar Tendon Window Defect Model
W Xu, Y Wang, E Liu, Y Sun, Z Luo, Z Xu, W Liu, L Zhong, Y Lv, A Wang, Z Tang, S Li, L Yang |
Tissue Engineering Part A | 2013 |
|
BMP12 induces tenogenic differentiation of adipose-derived stromal cells
H Shen, RH Gelberman, MJ Silva, SE Sakiyama-Elbert, S Thomopoulos |
PloS one | 2013 |
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Controlled delivery of mesenchymal stem cells and growth factors using a nanofiber scaffold for tendon repair
CN Manning, AG Schwartz, W Liu, J Xie, N Havlioglu, SE Sakiyama-Elbert, MJ Silva, Y Xia, RH Gelberman, S Thomopoulos |
Acta Biomaterialia | 2013 |
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Multipotent Mesenchymal Stem Cells from Human Subacromial Bursa: Potential for Cell Based Tendon Tissue Engineering
N Song, AD Armstong, F Li, C Niyibizi |
Tissue Engineering Part A | 2013 |
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Genetics of disc-related disorders: current findings and lessons from other complex diseases
A Näkki, MC Battié, J Kaprio |
European Spine Journal | 2013 |
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Genetics of Bone Biology and Skeletal Disease
CS Kovacs |
Genetics of Bone Biology and Skeletal Disease | 2013 |
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Tenogenic differentiation of equine adipose-tissue-derived stem cells under the influence of tensile strain, growth differentiation factors and various oxygen tensions
O Raabe, K Shell, D Fietz, C Freitag, A Ohrndorf, HJ Christ, S Wenisch, S Arnhold |
Cell and Tissue Research | 2013 |
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An Adhesive Bone Marrow Scaffold and Bone Morphogenetic-2 Protein Carrier for Cartilage Tissue Engineering
JA Simson, IA Strehin, Q Lu, MO Uy, JH Elisseeff |
Biomacromolecules | 2013 |
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Oral Wound Healing: Larjava/Oral Wound Healing
A Turabelidze, LA DiPietro |
Oral Wound Healing: Larjava/Oral Wound Healing | 2013 |
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Histopathological changes in tendinopathy--potential roles of BMPs?
PP Lui |
Rheumatology | 2013 |
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The genetics of sports injuries and athletic performance
N Maffulli, K Margiotti, UG Longo, M Loppini, VM Fazio, V Denaro |
2013 | |
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Advances in Regenerative Orthopedics
CH Evans |
Mayo Clinic Proceedings | 2013 |
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Diclofenac and triamcinolone acetonide impair tenocytic differentiation and promote adipocytic differentiation of mesenchymal stem cells
M Fredriksson, Y Li, A Stålman, LA Haldosén, L Felländer-Tsai |
Journal of orthopaedic surgery and research | 2013 |
|
Composite Growth Factor Supplementation Strategies to Enhance Tenocyte Bioactivity in Aligned Collagen-GAG Scaffolds
SR Caliari, BA Harley |
Tissue Engineering Part A | 2013 |
|
GDFs promote tenogenic characteristics on human periodontal ligament-derived cells in culture at late passages
D Xia, Y Sumita, Y Liu, Y Tai, J Wang, M Uehara, H Agata, H Kagami, Z Fan, I Asahina, S Wang, SD Tran |
Growth Factors | 2013 |
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Tendon and ligament regeneration and repair: Clinical relevance and developmental paradigm: Tendon and Ligament Regeneration and Repair
G Yang, BB Rothrauff, RS Tuan |
Birth Defects Research Part C Embryo Today Reviews | 2013 |
|
Cellular distribution and gene expression profile during flexor tendon graft repair: A novel tissue engineering approach *
SC Juneja |
Journal of Tissue Engineering | 2013 |
|
BMP12 induces tenogenic differentiation of adipose-derived stromal cells
H Shen, RH Gelberman, MJ Silva, SE Sakiyama-Elbert, S Thomopoulos, HA Awad |
PloS one | 2013 |
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Multiple Channeling Improves the Structural Integrity of Rotator Cuff Repair
CH Jo, JS Shin, IW Park, H Kim, SY Lee |
The American journal of sports medicine | 2013 |
|
The Multiple Ligament Injured Knee
GC Fanelli |
2013 | |
|
Shoulder Arthroscopy
G Milano, A Grasso |
2013 | |
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An Adhesive Bone Marrow Scaffold and Bone Morphogenetic-2 Protein Carrier for Cartilage Tissue Engineering
JA Simson, IA Strehin, Q Lu, MO Uy, JH Elisseeff |
Biomacromolecules | 2013 |
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Bone Marrow-Derived Matrix Metalloproteinase-9 Is Associated with Fibrous Adhesion Formation after Murine Flexor Tendon Injury
AE Loiselle, BJ Frisch, M Wolenski, JA Jacobson, LM Calvi, EM Schwarz, HA Awad, RJ O'Keefe |
PloS one | 2012 |
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Immunohistological Localization of BMP-2, BMP-7, and Their Receptors in Knee Joints with Focal Cartilage Lesions
H Schmal, AT Mehlhorn, IH Pilz, D Dovi-Akue, C Kirchhoff, NP Südkamp, U Gerlach, C Lohrmann, P Niemeyer |
The Scientific World JOURNAL | 2012 |
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Decellularized tendon extracellular matrix-a valuable approach for tendon reconstruction?
G Schulze-Tanzil, O Al-Sadi, W Ertel, A Lohan |
Cells | 2012 |
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Cytokines in rotator cuff degeneration and repair
A Bedi, T Maak, C Walsh, SA Rodeo, D Grande, DM Dines, JS Dines |
Journal of Shoulder and Elbow Surgery | 2012 |
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Chondroitin sulfate synthase 1 (Chsy1) is required for bone development and digit patterning
DG Wilson, K Phamluong, WY Lin, L Diehl, AS Peterson, F Martin, MJ Solloway |
Developmental Biology | 2012 |
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BMPs are mediators in tissue crosstalk of the regenerating musculoskeletal system
K Ruschke, C Hiepen, J Becker, P Knaus |
Cell & Tissue Research | 2012 |
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Maturation of periodontal tissues following implantation of rhGDF-5/β-TCP in one-wall intra-bony defects in dogs: 24-week histological observations
JS Lee, UM Wikesjö, JC Park, YJ Jang, SD Pippig, P Bastone, SH Choi, CK Kim |
Journal of Clinical Periodontology | 2012 |
|
Regenerative Biology and Medicine
DL Stocum |
Regenerative Biology and Medicine | 2012 |
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Expression of BMP-receptor type 1A correlates with progress of osteoarthritis in human knee joints with focal cartilage lesions
H Schmal, IH Pilz, AT Mehlhorn, D Dovi-Akue, C Kirchhoff, NP Südkamp, U Gerlach, P Niemeyer |
Cytotherapy | 2012 |
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The effect of growth factors on both collagen synthesis and tensile strength of engineered human ligaments
P Hagerty, A Lee, S Calve, CA Lee, M Vidal, K Baar |
Biomaterials | 2012 |
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Alveolar ridge augmentation using implants coated with recombinant human growth/differentiation factor -5 (rhGDF-5). Radiographic observations
KN Leknes, J Yang, M Qahash, G Polimeni, C Susin, UM Wikesjö |
Clinical Oral Implants Research | 2012 |
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Biologics in the Management of Rotator Cuff Surgery
ME Angeline, SA Rodeo |
Clinics in Sports Medicine | 2012 |
|
Outcomes of Rotator Cuff Surgery
AW Aleem, RH Brophy |
Clinics in Sports Medicine | 2012 |
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Evaluation of Stem Cell-to-Tenocyte Differentiation By Atomic Force Microscopy to Measure Cellular Elastic Moduli
Y Morita, T Mukai, Y Ju, S Watanabe |
Cell Biochemistry and Biophysics | 2012 |
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Biological agents and cell therapies in periodontal regeneration: Biological agents and cell therapies in periodontal regeneration
H Larjava, Y Yang, E Putnins, J Heino, L Häkkinen |
Endodontic Topics | 2012 |
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Skeletal muscle and bone marrow derived stromal cells: a comparison of tenocyte differentiation capabilities
AA Sassoon, Y Ozasa, T Chikenji, YL Sun, DR Larson, ML Maas, C Zhao, J Jen, PC Amadio |
Journal of Orthopaedic Research | 2012 |
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Allogenous Tendon Stem/Progenitor Cells in Silk Scaffold for Functional Shoulder Repair
W Shen, J Chen, Z Yin, X Chen, H Liu, BC Heng, W Chen, HW Ouyang |
Cell Transplantation | 2012 |
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Mesenchymal Stem Cell Therapy
LG Chase, MC Vemuri |
2012 | |
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Structural Interfaces and Attachments in Biology
S Thomopoulos, V Birman, GM Genin |
2012 | |
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Conversion of mechanical force into TGF-β-mediated biochemical signals
T Maeda, T Sakabe, A Sunaga, K Sakai, AL Rivera, DR Keene, T Sasaki, E Stavnezer, J Iannotti, R Schweitzer, D Ilic, H Baskaran, T Sakai |
Current biology : CB | 2011 |
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Engineering Spatial Control of Multiple Differentiation Fates within a Stem Cell Population
ED Ker, B Chu, JA Phillippi, B Gharaibeh, J Huard, LE Weiss, PG Campbell |
Biomaterials | 2011 |
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Delayed Fracture Healing in Growth Differentiation Factor 5-deficient Mice: A Pilot Study
CM Coleman, BH Scheremeta, AT Boyce, RL Mauck, RS Tuan |
Clinical Orthopaedics and Related Research® | 2011 |
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The effect of multiple channeling on the structural integrity of repaired rotator cuff
CH Jo, KS Yoon, JH Lee, SB Kang, JH Lee, HS Han, SH Rhee, JS Shin |
Knee Surgery, Sports Traumatology, Arthroscopy | 2011 |
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Growth differentiation factor-5 regulation of extracellular matrix gene expression in murine tendon fibroblasts
M Hogan, K Girish, R James, G Balian, S Hurwitz, AB Chhabra |
Journal of Tissue Engineering and Regenerative Medicine | 2011 |
|
Tenogenic differentiation of stem cells for tendon repair-what is the current evidence?
PP Lui, YF Rui, M Ni, KM Chan |
Journal of Tissue Engineering and Regenerative Medicine | 2011 |
|
Growth/differentiation factor-5 modulates the synthesis and expression of extracellular matrix and cell-adhesion-related molecules of rat Achilles tendon fibroblasts
TC Keller, MC Hogan, G Kesturu, R James, G Balian, AB Chhabra |
Connective Tissue Research | 2011 |
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Resultados funcionales tras la reparación artroscópica de roturas masivas del manguito rotador: influencia de la aplicación de plasma rico en plaquetas asociado a fibrina
JM Márquez, JM Díez, R Barco, S Antuña |
Revista Española de Cirugía Ortopédica y Traumatología | 2011 |
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Treatment with rhBMP12 or rhBMP13 increase the rate and the quality of rat Achilles tendon repair
SA Jelinsky, L Li, D Ellis, J Archambault, J Li, MS Andre, C Morris, H Seeherman |
Journal of Orthopaedic Research | 2011 |
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Regenerative medicine and connective tissues: cartilage versus tendon
JA Montero, CI Lorda-Diez, JM Hurlé |
Journal of Tissue Engineering and Regenerative Medicine | 2011 |
|
Braided Nanofibrous Scaffold for Tendon and Ligament Tissue Engineering
JG Barber, AM Handorf, TJ Allee, WJ Li |
Tissue Engineering Part A | 2011 |
|
Bone Morphogenetic Proteins: A critical review
B Bragdon, O Moseychuk, S Saldanha, D King, J Julian, A Nohe |
Cellular Signalling | 2011 |
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Functional results after arthroscopic repair of massive rotator cuff tears; influence of the application platelet-rich plasma combined with fibrin
JM Márquez, JM Díez, R Barco, S Antuña |
Revista Española de Cirugía Ortopédica y Traumatología (English Edition) | 2011 |
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What We Should Know Before Using Tissue Engineering Techniques to Repair Injured Tendons: A Developmental Biology Perspective
CF Liu, L Aschbacher-Smith, NJ Barthelery, N Dyment, D Butler, C Wylie |
Tissue engineering. Part B, Reviews | 2011 |
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Tendon tissue engineering: Adipose 1 derived stem cell and GDF-5 mediated regeneration using electrospun matrix systems
R James, SG Kumbar, CT Laurencin, G Balian, AB Chhabra |
Biomedical Materials | 2011 |
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Divergent activities of osteogenic BMP2, and tenogenic BMP12 and BMP13 independent of receptor binding affinities
SP Berasi, U Varadarajan, J Archambault, M Cain, TA Souza, A Abouzeid, J Li, CT Brown, AJ Dorner, HJ Seeherman, SA Jelinsky |
Growth factors (Chur, Switzerland) | 2011 |
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Mesenchymal Stem Cell Characteristics of Human Anterior Cruciate Ligament Outgrowth Cells
AF Steinert, M Kunz, P Prager, T Barthel, F Jakob, U Nöth, MM Murray, CH Evans, RM Porter |
Tissue Engineering Part A | 2011 |
|
Musculoskeletal diseases—tendon
T Sakabe, T Sakai |
British Medical Bulletin | 2011 |
|
Current Topics in Developmental Biology
JE Qualls, PJ Murray |
Cancer and Development | 2011 |
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Green's Operative Hand Surgery
SH Kozin |
Green's Operative Hand Surgery | 2011 |
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Role of Growth Factors in Rotator Cuff Healing:
F Oliva, AG Via, N Maffulli |
Sports Medicine and Arthroscopy Review | 2011 |
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Gene therapy with growth factors for periodontal tissue engineering--a review
S Sood, S Gupta, A Mahendra |
Medicina Oral, Patología Oral y Cirugía Bucal | 2011 |
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Gene therapy with growth factors for periodontal tissue engineering–A review
S Sood, S Gupta, A Mahendra |
Medicina Oral, Patología Oral y Cirugía Bucal | 2011 |
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Tissue Engineering Solutions for Tendon Repair:
MC Hogan, N Bagayoko, R James, T Starnes, A Katz, BA Chhabra |
The Journal of the American Academy of Orthopaedic Surgeons | 2011 |
|
Biologic and Pharmacologic Augmentation of Rotator Cuff Repairs:
SL Edwards, ST Lynch, MD Saltzman, MA Terry, GW Nuber |
The Journal of the American Academy of Orthopaedic Surgeons | 2011 |
|
BMP-12 Treatment of Adult Mesenchymal Stem Cells In Vitro Augments Tendon-Like Tissue Formation and Defect Repair In Vivo
JY Lee, Z Zhou, PJ Taub, M Ramcharan, Y Li, T Akinbiyi, ER Maharam, DJ Leong, DM Laudier, T Ruike, PJ Torina, M Zaidi, RJ Majeska, MB Schaffler, EL Flatow, HB Sun, S Agarwal |
PloS one | 2011 |
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The effects of growth and differentiation factor 5 on bone marrow stromal cell transplants in an in vitro tendon healing model
M Hayashi, C Zhao, KN An, PC Amadio |
The Journal of Hand Surgery, European Volume | 2011 |
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The promoting effect of pentadecapeptide BPC 157 on tendon healing involves tendon outgrowth, cell survival, and cell migration
CH Chang, WC Tsai, MS Lin, YH Hsu, JH Pang |
Journal of applied physiology | 2011 |
|
Adipose-Derived Mesenchymal Stem Cells Treated with Growth Differentiation Factor-5 Express Tendon-Specific Markers
A Park, MV Hogan, GS Kesturu, R James, G Balian, AB Chhabra |
Tissue Engineering Part A | 2010 |
|
BMP12 and BMP13 gene transfer induce ligamentogenic differentiation in mesenchymal progenitor and anterior cruciate ligament cells
M Haddad-Weber, P Prager, M Kunz, L Seefried, F Jakob, MM Murray, CH Evans, U Nöth, AF Steinert |
Cytotherapy | 2010 |
|
Stem cells for tendon tissue engineering and regeneration
Z Yin, X Chen, J Chen, HW Ouyang |
Expert Opinion on Biological Therapy | 2010 |
|
Regenerative medicine and biomaterials for the repair of connective tissues
R Andriamanalijaona |
Regenerative medicine and biomaterials for the repair of connective tissues | 2010 |
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Tissue engineered biological augmentation for tendon healing: a systematic review
UG Longo, A Lamberti, N Maffulli, V Denaro |
British Medical Bulletin | 2010 |
|
New Insight Into Healing Mechanisms of the Infarcted Heart⁎⁎Editorials published in the Journal of the American College of Cardiology reflect the views of the authors and do not necessarily represent the views of JACC or the American College of Cardiology
G Ertl, T Thum |
Journal of the American College of Cardiology | 2010 |
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Bone Morphogenetic Proteins and Cancer
JP Thawani, AC Wang, KD Than, CY Lin, FL Marca, P Park |
Neurosurgery | 2010 |
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Growth/differentiation factor-5: a candidate therapeutic agent for periodontal regeneration? A review of pre-clinical data
YR Moore, DP Dickinson, UM Wikesjö |
Journal of Clinical Periodontology | 2010 |
|
Periodontal wound healing/regeneration following implantation of recombinant human growth/differentiation factor-5 in aβ-tricalcium phosphate carrier into one-wall intrabony defects in dogs
JS Lee, UM Wikesjö, UW Jung, SH Choi, S Pippig, M Siedler, CK Kim |
Journal of Clinical Periodontology | 2010 |
|
Evaluation of an injectable rhGDF-5/PLGA construct for minimally invasive periodontal regenerative procedures: a histological study in the dog
DH Kwon, W Bennett, S Herberg, P Bastone, S Pippig, NA Rodriguez, C Susin, UM Wikesjö |
Journal of Clinical Periodontology | 2010 |
|
A bFGF-releasing silk/PLGA-based biohybrid scaffold for ligament/tendon tissue engineering using mesenchymal progenitor cells
S Sahoo, SL Toh, JC Goh |
Biomaterials | 2010 |
|
Growth/differentiation factor-5 significantly enhances periodontal wound healing/regeneration compared with platelet-derived growth factor-BB in dogs
HR Kwon, UM Wikesjö, JC Park, YT Kim, P Bastone, SD Pippig, CK Kim |
Journal of Clinical Periodontology | 2010 |
|
The effect of two point mutations in GDF-5 on ectopic bone formation in a β-tricalciumphosphate scaffold
P Kasten, I Beyen, D Bormann, R Luginbühl, F Plöger, W Richter |
Biomaterials | 2010 |
|
The Indications and Use of Bone Morphogenetic Proteins in Foot, Ankle, and Tibia Surgery
SF El-Amin, MC Hogan, AA Allen, J Hinds, CT Laurencin |
Foot and Ankle Clinics of North America | 2010 |
|
Pentadecapeptide BPC 157 (PL 14736) improves ligament healing in the rat
T Cerovecki, I Bojanic, L Brcic, B Radic, I Vukoja, S Seiwerth, P Sikiric |
Journal of Orthopaedic Research | 2010 |
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Components of the transforming growth factor- family and the pathogenesis of human Achilles tendon pathology--a genetic association study
M Posthumus, M Collins, J Cook, CJ Handley, WJ Ribbans, RK Smith, MP Schwellnus, SM Raleigh |
Rheumatology | 2010 |
|
Embryology of Congenital Differences
SH Kozin |
Journal of Pediatric Orthopaedics | 2010 |
|
Association between expression of the bone morphogenetic proteins 2 and 7 in the repair of circumscribed cartilage lesions with clinical outcome
H Schmal, P Niemeyer, J Zwingmann, F Stoffel, NP Südkamp, AT Mehlhorn |
BMC musculoskeletal disorders | 2010 |
|
Use of Matrices as a Tissue Substitute in Shoulder Surgery
Z Working, RV West |
Operative techniques in orthopaedics | 2010 |
|
Periodontal Regeneration: Focus on Growth and Differentiation Factors
J Lee, A Stavropoulos, C Susin, UM Wikesjö |
Dental clinics of North America | 2010 |
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Biological implications of growth factors in bone remodeling following fracture, surgical resection and bonegrafting. Part 1: Transforming growth factors, bone morphogenetic proteins and related factors
M Mori, M Motohashi, T Nishikawa, K Masuno, A Tanaka, T Ohta, S Sumitomo, M Shikimori |
Asian Journal of Oral and Maxillofacial Surgery | 2010 |
|
Evaluation of early cellular influences of bone morphogenetic proteins 12 and 2 on equine superficial digital flexor tenocytes and bone marrow–derived mesenchymal stem cells in vitro
SJ Murray, KS Santangelo, AL Bertone |
American Journal of Veterinary Research | 2010 |
|
Cell Therapy in Tendon Disorders: What Is the Current Evidence?
H Obaid, D Connell |
The American journal of sports medicine | 2010 |
|
Prostaglandin E 2 receptor subtype EP2- and EP4-regulated gene expression profiling in human ciliary smooth muscle cells
A Reitmair, NW Lambrecht, I Yakubov, A Nieves, D Old, Y Donde, D Dinh, R Burk, G Sachs, WB Im, L Wheeler |
Physiological genomics | 2010 |
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Regeneration of Bone- and Tendon/Ligament-Like Tissues Induced by Gene Transfer of Bone Morphogenetic Protein-12 in a Rat Bone Defect
S Kuroda, N Goto, M Suzuki, K Kaneda, K Ohya, H Shimokawa, S Kasugai, HW Kim |
Journal of Tissue Engineering | 2010 |
|
Adenoviral-Mediated Gene Transfer of Human Bone Morphogenetic Protein–13 Does Not Improve Rotator Cuff Healing in a Rat Model
LV Gulotta, D Kovacevic, JD Packer, JR Ehteshami, SA Rodeo |
The American journal of sports medicine | 2010 |
|
Stepwise Differentiation of Human Embryonic Stem Cells Promotes Tendon Regeneration by Secreting Fetal Tendon Matrix and Differentiation Factors
X Chen, XH Song, Z Yin, XH Zou, LL Wang, H Hu, T Cao, M Zheng, HW Ouyang |
Stem Cells | 2009 |
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Remodeling of murine intrasynovial tendon adhesions following injury: MMP and neotendon gene expression
AE Loiselle, GA Bragdon, JA Jacobson, S Hasslund, ZE Cortes, EM Schwarz, DJ Mitten, HA Awad, RJ O'Keefe |
Journal of Orthopaedic Research | 2009 |
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Pathogenesis of tendinopathies: inflammation or degeneration?
M Abate, KG Silbernagel, C Siljeholm, AD Iorio, DD Amicis, V Salini, S Werner, R Paganelli |
Arthritis Research & Therapy | 2009 |
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Temporomandibular joint formation requires two distinct hedgehog-dependent steps
P Purcell, BW Joo, JK Hu, PV Tran, ML Calicchio, DJ O'Connell, RL Maas, CJ Tabin |
Proceedings of the National Academy of Sciences | 2009 |
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A novel polymorphism of GDF5 gene and its association with body measurement traits in Bos taurus and Bos indicus breeds
YF Liu, LS Zan, K Li, SP Zhao, YP Xin, Q Lin, WQ Tian, ZW Wang |
Molecular Biology Reports | 2009 |
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Identification of a Tendon Phenotype in GDF6 Deficient Mice
B Mikic, K Rossmeier, L Bierwert |
The Anatomical Record: Advances in Integrative Anatomy and Evolutionary Biology | 2009 |
|
Sexual dimorphism in the effect of GDF-6 deficiency on murine tendon
B Mikic, K Rossmeier, LA Bierwert |
Journal of Orthopaedic Research | 2009 |
|
Periodontal wound healing/regeneration following implantation of recombinant human growth/differentiation factor-5 (rhGDF-5) in an absorbable collagen sponge carrier into one-wall intrabony defects in dogs: a dose-range study
TG Kim, UM Wikesjö, KS Cho, JK Chai, SD Pippig, M Siedler, CK Kim |
Journal of Clinical Periodontology | 2009 |
|
The KK-Periome database for transcripts of periodontal ligament development
M Saito, E Nishida, T Sasaki, T Yoneda, N Shimizu |
Journal of Experimental Zoology Part B: Molecular and Developmental Evolution | 2009 |
|
Cell sheet engineering and other novel cell-based approaches to periodontal regeneration
I Ishikawa, T Iwata, K Washio, T Okano, T Nagasawa, K Iwasaki, T Ando |
Periodontology 2000 | 2009 |
|
BMP-13 emerges as a potential inhibitor of bone formation
B Shen, D Bhargav, A Wei, LA Williams, H Tao, DD Ma, AD Diwan |
International journal of biological sciences | 2009 |
|
Growth Factors for Rotator Cuff Repair
LV Gulotta, SA Rodeo |
Clinics in Sports Medicine | 2009 |
|
Differential effects of growth differentiation factor-5 on porcine dental papilla- and follicle-derived cells
Y Sumita, MJ Honda, M Ueda, I Asahina, H Kagami |
Growth Factors | 2009 |
|
Effects of cartilage-derived morphogenetic protein-3 on the expression of chondrogenic and osteoblastic markers in the pluripotent mesenchymal C3H10T1/2 cell line
LC Yeh, JC Lee |
Growth Factors | 2009 |
|
Effect of Bone Morphogenetic Protein-12 Gene Transfer on Posterior Cruciate Ligament Healing in a Rabbit Model
Y Ma, X Zhang, J Wang, P Liu, L Zhao, C Zhou, Y Ao |
The American journal of sports medicine | 2009 |
|
Fundamentals of Tissue Engineering and Regenerative Medicine
U Meyer, J Handschel, HP Wiesmann, T Meyer |
2009 | |
|
Molecular targets for tendon neoformation
Hadi Aslan, Nadav Kimelman-Bleich, Gadi Pelled, Dan Gazit |
Journal of Clinical Investigation | 2008 |
|
The Effects of GDF-5 and Uniaxial Strain on Mesenchymal Stem Cells in 3-D Culture
E Farng, AR Urdaneta, D Barba, S Esmende, DR McAllister |
Clinical Orthopaedics and Related Research | 2008 |
|
Freeze-dried Tendon Allografts as Tissue-engineering Scaffolds for Gdf5 Gene Delivery
P Basile, T Dadali, J Jacobson, S Hasslund, M Ulrich-Vinther, K Søballe, Y Nishio, MH Drissi, HN Langstein, DJ Mitten, RJ O'Keefe, EM Schwarz, HA Awad |
Molecular Therapy | 2008 |
|
Tendinopathy and tendon injury: The future
P Sharma, N Maffulli |
Disability and Rehabilitation | 2008 |
|
Relationship of bone morphogenetic proteins to disease activity and radiographic damage in patients with ankylosing spondylitis
MC Park, YB Park, SK Lee |
Scandinavian Journal of Rheumatology | 2008 |
|
The Basic Science of Tendinopathy
Y Xu, GA Murrell |
Clinical Orthopaedics and Related Research | 2008 |
|
Tendons of myostatin-deficient mice are small, brittle, and hypocellular
CL Mendias, KI Bakhurin, JA Faulkner |
Proceedings of the National Academy of Sciences | 2008 |
|
Biological Augmentation of Rotator Cuff Tendon Repair
D Kovacevic, SA Rodeo |
Clinical Orthopaedics and Related Research | 2008 |
|
Effect of GDF-7 deficiency on tail tendon phenotype in mice
B Mikic, R Entwistle, K Rossmeier, LA Bierwert |
Journal of Orthopaedic Research | 2008 |
|
Bone and soft connective tissue alterations result from loss of fibrillin-2 expression
R Boregowda, E Paul, J White, TM Ritty |
Matrix Biology | 2008 |
|
Bone morphogenetic protein-7 regulates differentially the mRNA expression of bone morphogenetic proteins and their receptors in rat achilles and patellar tendon cell cultures
LC Yeh, AD Tsai, JC Lee |
Journal of Cellular Biochemistry | 2008 |
|
Ex vivo adenoviral transfer of bone morphogenetic protein 12 (BMP-12) cDNA improves Achilles tendon healing in a rat model
M Majewski, O Betz, PE Ochsner, F Liu, RM Porter, CH Evans |
Gene Therapy | 2008 |
|
Assessment of the potential of growth factors for localized alveolar ridge augmentation: a systematic review
RE Jung, DS Thoma, CH Hammerle |
Journal of Clinical Periodontology | 2008 |
|
Tendon: Biology, Biomechanics, Repair, Growth Factors, and Evolving Treatment Options
R James, G Kesturu, G Balian, AB Chhabra |
The Journal of Hand Surgery | 2008 |
|
Injectable growthdifferentiation factor-5recombinant human collagen composite induces endochondral ossification via Sry-related HMG box 9 (Sox9)expression and angiogenesis in murine calvariae
H Kadomatsu, T Matsuyama, T Yoshimoto, Y Negishi, H Sekiya, M Yamamoto, Y Izumi |
Journal of Periodontal Research | 2008 |
|
Development of an injectable composite as a carrier for growth factor-enhanced periodontal regeneration
S Herberg, M Siedler, S Pippig, A Schuetz, C Dony, CK Kim, UM Wikesjö |
Journal of Clinical Periodontology | 2008 |
|
Accelerated hypertrophic chondrocyte kinetics in GDF-7 deficient murine tibial growth plates
B Mikic, MP Ferreira, TC Battaglia, EB Hunziker |
Journal of Orthopaedic Research | 2008 |
|
Twenty-five years of tendon and ligament research
LA Dourte, AF Kuntz, LJ Soslowsky |
Journal of Orthopaedic Research | 2008 |
|
Tissue engineering approaches for the construction of a completely autologous tendon substitute
B Franco, V Vincenzo, DV Alessandro, C Tonello, G Abatangelo, F Mazzoleni |
Indian journal of plastic surgery : official publication of the Association of Plastic Surgeons of India | 2008 |
|
Controlled-release kinetics and biologic activity of platelet-derived growth factor-BB for use in flexor tendon repair
SE Sakiyama-Elbert, R Das, RH Gelberman, F Harwood, D Amiel, S Thomopoulos |
The Journal of Hand Surgery | 2008 |
|
Altered transforming growth factor-beta signaling in a murine model of thoracic aortic aneurysm
JA Jones, JR Barbour, RE Stroud, S Bouges, SL Stephens, FG Spinale, JS Ikonomidis |
Journal of Vascular Research | 2008 |
|
Unveiling the bmp13 enigma: redundant morphogen or crucial regulator?
LA Williams, D Bhargav, AD Diwan |
International journal of biological sciences | 2008 |
|
Mechanical Load and BMP Signaling During Tendon Repair: A Role for Follistatin?
P Eliasson, A Fahlgren, P Aspenberg |
Clinical Orthopaedics and Related Research | 2008 |
|
Temporale Expression von acht Wachstumsfaktoren in Sehnen-Knochenheilung bei einem Ratten-Supraspinatus-Modell
CC Würgler-Hauri, LA Dourte, TC Baradet, GR Williams, LJ Soslowsky |
Sport-Orthopädie - Sport-Traumatologie - Sports Orthopaedics and Traumatology | 2008 |
|
The effects of recombinant human bone morphogenetic protein-2, recombinant human bone morphogenetic protein-12, and adenoviral bone morphogenetic protein-12 on matrix synthesis in human annulus fibrosis and nucleus pulposus cells
L Gilbertson, SH Ahn, PN Teng, RK Studer, C Niyibizi, JD Kang |
The Spine Journal | 2008 |
|
Modulatory effects of inflammation and therapy on GDF‐5 expression in rheumatoid arthritis synovium
CP Bramlage, C Kaps, U Ungethüm, P Bramlage, M Koziolek, J Wessels, V Krenn, A Pruß, GA Müller, F Strutz, GR Burmester, T Häupl |
Scandinavian Journal of Rheumatology | 2008 |
|
Tendon and ligament engineering in the adult organism: mesenchymal stem cells and gene-therapeutic approaches
A Hoffmann, G Gross |
International Orthopaedics | 2007 |
|
Mesenchymal stromal cells. Biology of adult mesenchymal stem cells: regulation of niche, self-renewal and differentiation
CM Kolf, E Cho, RS Tuan |
Arthritis Research & Therapy | 2007 |
|
Trends for the Future as a Team Physician: Herodicus to Hereafter
J Whiteside, JR Andrews |
Clinics in Sports Medicine | 2007 |
|
Developmental failure of the intra-articular ligaments in mice with absence of growth differentiation factor 5
M Harada, M Takahara, P Zhe, M Otsuji, Y Iuchi, M Takagi, T Ogino |
Osteoarthritis and Cartilage | 2007 |
|
Effect of Transforming Growth Factor-Beta and Growth Differentiation Factor-5 on Proliferation and Matrix Production by Human Bone Marrow Stromal Cells Cultured on Braided Poly Lactic-Co-Glycolic Acid Scaffolds for Ligament Tissue Engineering
JM Jenner, F Eijk, DB Saris, WJ Willems, WJ Dhert, LB Creemers |
Tissue Engineering | 2007 |
|
GDF6, a Novel Locus for a Spectrum of Ocular Developmental Anomalies
M Asai-Coakwell, CR French, KM Berry, M Ye, R Koss, M Somerville, R Mueller, V Heyningen, AJ Waskiewicz, OJ Lehmann |
The American Journal of Human Genetics | 2007 |
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A functional polymorphism in the 5′ UTR of GDF5 is associated with susceptibility to osteoarthritis
Y Miyamoto, A Mabuchi, D Shi, T Kubo, Y Takatori, S Saito, M Fujioka, A Sudo, A Uchida, S Yamamoto, K Ozaki, M Takigawa, T Tanaka, Y Nakamura, Q Jiang, S Ikegawa |
Nature Genetics | 2007 |
|
Biologics in Shoulder Surgery: The Role of Adult Mesenchymal Stem Cells in Tendon Repair
CG Rios, MB McCarthy, C Arciero, JT Spang, RA Arciero, AD Mazzocca |
Techniques in Orthopaedics | 2007 |
|
The Role of Bone Morphogenetic Proteins in Rotator Cuff Tendon Repair
SA Rodeo |
Techniques in Orthopaedics | 2007 |
|
Chondrogenic differentiation of mouse bone marrow mesenchymal stem cells induced by cartilage-derived morphogenetic protein-2 in vitro
H Tian, S Yang, L Xu, Y Zhang, W Xu |
Journal of Huazhong University of Science and Technology | 2007 |
|
BMP7 promotes adipogenic but not osteo-/chondrogenic differentiation of adult human bone marrow-derived stem cells in high-density micro-mass culture
K Neumann, M Endres, J Ringe, B Flath, R Manz, T Häupl, M Sittinger, C Kaps |
Journal of Cellular Biochemistry | 2007 |
|
Osteoarthritis genetics: current status and future prospects
JM Wilkins, J Loughlin, SJ Snelling |
Future Rheumatology | 2007 |
|
Stem cells in veterinary medicine – attempts at regenerating equine tendon after injury
LE Richardson, J Dudhia, PD Clegg, R Smith |
Trends in Biotechnology | 2007 |
|
Elevated extracellular matrix production and degradation upon bone morphogenetic protein-2 (BMP-2) stimulation point toward a role for BMP-2 in cartilage repair and remodeling
EN Davidson, EL Vitters, PL van Lent, FA van de Loo, WB van Berg, PM van der Kraan |
Arthritis Research & Therapy | 2007 |
|
Mesenchymal stem cells: from biology to clinical use
M Krampera, M Franchini, G Pizzolo, G Aprili |
Blood transfusion = Trasfusione del sangue | 2007 |
|
Biologic augmentation of rotator cuff tendon repair
SA Rodeo |
Journal of Shoulder and Elbow Surgery | 2007 |
|
Temporal expression of 8 growth factors in tendon-to-bone healing in a rat supraspinatus model
CC Würgler-Hauri, LA Dourte, TC Baradet, GR Williams, LJ Soslowsky |
Journal of shoulder and elbow surgery / American Shoulder and Elbow Surgeons ... [et al.] | 2007 |
|
Analysis of osteochondro-induction using growth and differentiation factor-5 in rat muscle
N Kakudo, YB Wang, S Miyake, S Kushida, K Kusumoto |
Life Sciences | 2007 |
|
The Role of Transforming Growth Factor-β and Bone Morphogenetic Protein with Fibrin Glue in Healing of Bone-Tendon Junction Injury
HJ Kim, SW Kang, HC Lim, SB Han, JS Lee, L Prasad, YJ Kim, BS Kim, JH Park |
Connective Tissue Research | 2007 |
|
Modulation of VEGF Expression in Rat Bone Marrow Stromal Cells by GDF-5
K Sena, DR Sumner, AS Virdi |
Connective Tissue Research | 2007 |
|
On the Horizon From the ORS:
G Gibson, D Fyhrie |
The Journal of the American Academy of Orthopaedic Surgeons | 2007 |
|
Knie
J Jerosch, J Heisel, AB Imhoff |
2007 | |
|
Chondrogenic differentiation of mouse bone marrow mesenchymal stem cells induced by cartilage-derived morphogenetic protein-2 in vitro
H Tian, S Yang, L Xu, Y Zhang, W Xu |
Journal of Huazhong University of Science and Technology [Medical Sciences] | 2007 |
|
Neotendon Formation Induced by Manipulation of the Smad8 Signaling Pathway in Mesenchymal Stem Cells
Andrea Hoffmann, Gadi Pelled, Gadi Turgeman, Peter Eberle, Yoram Zilberman, Hadassah Shinar, Keren Keinan-Adamsky, Andreas Winkel, Sandra Shahab, Gil Navon, Gerhard Gross, and Dan Gazit |
Journal of Clinical Investigation | 2006 |
|
Growth factor delivery for oral and periodontal tissue engineering
D Kaigler, JA Cirelli, WV Giannobile |
Expert Opinion on Drug Delivery | 2006 |
|
The alchemy of tendon repair: a primer for the (S)mad scientist
DA Towler, RH Gelberman |
Journal of Clinical Investigation | 2006 |
|
Tissue engineering for tendon repair
PO Bagnaninchi, Y Yang, AJ el Haj, N Maffulli |
British journal of sports medicine | 2006 |
|
Where tendons and ligaments meet bone: attachment sites ('entheses') in relation to exercise and/or mechanical load
M Benjamin, H Toumi, JR Ralphs, G Bydder, TM Best, S Milz |
Journal of Anatomy | 2006 |
|
Potential roles of bone morphogenetic proteins (BMPs) in skeletal repair and regeneration
T Nakase, H Yoshikawa |
Journal of Bone and Mineral Metabolism | 2006 |
|
Global gene profiling reveals a downregulation of BMP gene expression in experimental atrophic nonunions compared to standard healing fractures
T Niikura, DJ Hak, AH Reddi |
Journal of Orthopaedic Research | 2006 |
|
Recombinant human growth/differentiation factor-5 (rhGDF-5) induced bone formation in murine calvariae
T Yoshimoto, M Yamamoto, H Kadomatsu, K Sakoda, Y Yonamine, Y Izumi |
Journal of Periodontal Research | 2006 |
|
Achilles Tendon characterization in GDF-7 deficient mice
B Mikic, LA Bierwert, D Tsou |
Journal of Orthopaedic Research | 2006 |
|
Establishment of immortalized dental follicle cells for generating periodontal ligament in vivo
T Yokoi, M Saito, T Kiyono, S Iseki, K Kosaka, E Nishida, T Tsubakimoto, H Harada, K Eto, T Noguchi, T Teranaka |
Cell and Tissue Research | 2006 |
|
Superior Effect of MD05, Beta-Tricalcium Phosphate Coated With Recombinant Human Growth/Differentiation Factor-5, Compared to Conventional Bone Substitutes in the Rat Calvarial Defect Model
S Poehling, SD Pippig, K Hellerbrand, M Siedler, A Schütz, C Dony |
Journal of Periodontology | 2006 |
|
Tendon and ligament engineering: from cell biology toin vivoapplication
A Hoffmann, G Gross |
Regenerative Medicine | 2006 |
|
Mesenchymal stem cells for bone, cartilage, tendon and skeletal muscle repair
M Krampera, G Pizzolo, G Aprili, M Franchini |
Bone | 2006 |
|
Eye and neural defects associated with loss of GDF6
ML Hanel, C Hensey |
BMC Developmental Biology | 2006 |
|
Tissue Engineering for Anterior Cruciate Ligament Reconstruction: A Review of Current Strategies
FA Petrigliano, DR McAllister, BM Wu |
Arthroscopy: The Journal of Arthroscopic & Related Surgery | 2006 |
|
Geometric and Material Contributions to Whole Bone Structural Behavior in GDF-7-Deficient Mice
A Maloul, K Rossmeier, B Mikic, V Pogue, T Battaglia |
Connective Tissue Research | 2006 |
|
CDMP1/GDF5 Has Specific Processing Requirements That Restrict Its Action to Joint Surfaces
JT Thomas, D Prakash, K Weih, M Moos |
The Journal of biological chemistry | 2006 |
|
Activating and Deactivating Mutations in the Receptor Interaction Site of GDF5 Cause Symphalangism or Brachydactyly Type A2
Petra Seemann, Raphaela Schwappacher, Klaus W. Kjaer, Deborah Krakow, Katarina Lehmann, Katherine Dawson, Sigmar Stricker, Jens Pohl, Frank Plöger, Eike Staub, Joachim Nickel, Walter Sebald, Petra Knaus, Stefan Mundlos |
Journal of Clinical Investigation | 2005 |
|
Stimulatory effects of distinct members of the bone morphogenetic protein family on ligament fibroblasts
K Bobacz, R Ullrich, L Amoyo, L Erlacher, JS Smolen, WB Graninger |
Annals of the rheumatic diseases | 2005 |
|
Downregulation of the expression of bone morphogenetic protein 7 in experimental pyelonephritis
NK Biyikli, H Tugtepe, F Cakalagaoglu, A Ilki, H Alpay |
Pediatric Nephrology | 2005 |
|
The role of growth/differentiation factor 5 (GDF5) in the induction and survival of midbrain dopaminergic neurones: relevance to Parkinson's disease treatment
AM Sullivan, GW O'Keeffe |
Journal of Anatomy | 2005 |
|
Effect of GDF-5 on ligament healing
T Tashiro, H Hiraoka, Y Ikeda, T Ohnuki, R Suzuki, T Ochi, K Nakamura, N Fukui |
Journal of Orthopaedic Research | 2005 |
|
Cartilage-derived morphogenetic proteins induce osteogenic gene expression in the C2C12 mesenchymal cell line
LC Yeh, AD Tsai, JC Lee |
Journal of Cellular Biochemistry | 2005 |
|
Mesenchymal stem cells differentiate into tenocytes by bone morphogenetic protein (BMP) 12 gene transfer
QW Wang, ZL Chen, YJ Piao |
Journal of Bioscience and Bioengineering | 2005 |
|
Tendon and ligament: Development, repair and disease
S Tozer, D Duprez |
Birth Defects Research Part C: Embryo Today: Reviews | 2005 |
|
The Future: Rehabilitation, Gene Therapy, Optimization of Healing
P Sharma, N Maffulli |
Foot and Ankle Clinics of North America | 2005 |
|
Tendon properties in interleukin-4 and interleukin-6 knockout mice
TW Lin, L Cardenas, LJ Soslowsky |
Journal of Biomechanics | 2005 |
|
The Use of Growth Factors on Tendon Injuries
V Mehta, D Mass |
Journal of Hand Therapy | 2005 |
|
Biological considerations of tendon graft incorporation within the bone tunnel
BA Zelle, C Lattermann, A Chhabra, FH Fu, J Huard |
Operative techniques in orthopaedics | 2005 |
|
New dimensions in tissue engineering: possible models for human physiology: Modelling physiology with engineered tissues
K Baar |
Experimental Physiology | 2005 |
|
Adenovirus-Mediated Gene Transfer of Growth and Differentiation Factor-5 into Tenocytes and the Healing Rat Achilles Tendon
M Rickert, H Wang, P Wieloch, H Lorenz, E Steck, D Sabo, W Richter |
Connective Tissue Research | 2005 |
|
TENDON INJURY AND TENDINOPATHY: HEALING AND REPAIR
P Sharma, N Maffulli |
The Journal of Bone and Joint Surgery. American volume. | 2005 |
|
Identification of Receptors and Signaling Pathways for Orphan Bone Morphogenetic Protein/Growth Differentiation Factor Ligands Based on Genomic Analyses
S Mazerbourg, K Sangkuhl, CW Luo, S Sudo, C Klein, AJ Hsueh |
The Journal of biological chemistry | 2005 |
|
Tendon Injuries
N Maffulli, P Renström, WB Leadbetter |
2005 | |
|
BMP Receptor Signaling Is Required for Postnatal Maintenance of Articular Cartilage
RB Rountree, M Schoor, H Chen, ME Marks, V Harley, Y Mishina, DM Kingsley |
PLoS Biology | 2004 |
|
Developmental failure of phalanges in the absence of growth/differentiation factor 5
M Takahara, M Harada, D Guan, M Otsuji, T Naruse, M Takagi, T Ogino |
Bone | 2004 |
|
Signals regulating tendon formation during chick embryonic development
F Edom-Vovard, D Duprez |
Developmental Dynamics | 2004 |
|
Cartilage-derived morphogenetic proteins enhance the osteogenic protein-1-induced osteoblastic cell differentiation of C2C12 cells
LC Yeh, AD Tsai, MC Zavala, JC Lee |
Journal of Cellular Physiology | 2004 |
|
Effect of recombinant human bone morphogenetic protein-12 (rhBMP-12) on regeneration of periodontal attachment following tooth replantation in dogs. A pilot study
RG Sorensen, G Polimeni, A Kinoshita, JM Wozney, UM Wikesjo |
Journal of Clinical Periodontology | 2004 |
|
Periodontal repair in dogs: effect of recombinant human bone morphogenetic protein-12 (rhBMP-12) on regeneration of alveolar bone and periodontal attachment. A pilot study
UM Wikesjo, RG Sorensen, A Kinoshita, XJ Li, JM Wozney |
Journal of Clinical Periodontology | 2004 |
|
Evaluation of HealosMP52 Osteoinductive Bone Graft for Instrumented Lumbar Intertransverse Process Fusion in Sheep
DH Kim, TA Jahng, TS Fu, HY Zhang, SA Novak |
Spine | 2004 |
|
Collagen and Proteoglycan Abnormalities in the GDF-5-Deficient Mice and Molecular Changes When Treating Disk Cells With Recombinant Growth Factor
X Li, BM Leo, G Beck, G Balian, GD Anderson |
Spine | 2004 |
|
Adenovirus Mediated BMP-13 Gene Transfer Induces Chondrogenic Differentiation of Murine Mesenchymal Progenitor Cells
H Nochi, JH Sung, J Lou, HD Adkisson, WJ Maloney, KA Hruska |
Journal of Bone and Mineral Research | 2004 |
|
Crystallization and preliminary X-ray diffraction analysis of human growth and differentiation factor 5 (GDF-5)
TD Mueller, M Gottermeier, W Sebald, J Nickel |
Acta crystallographica. Section F, Structural biology and crystallization communications | 2004 |
|
Immunohistochemical Characterization of Cells in Adult Human Patellar Tendons
FS Chuen, CY Chuk, WY Ping, WW Nar, HL Kim, CK Ming |
Journal of Histochemistry & Cytochemistry | 2004 |
|
Enhanced Repair of the Anterior Cruciate Ligament by in Situ Gene Transfer: Evaluation in an in Vitro Model
A Pascher, AF Steinert, GD Palmer, O Betz, JN Gouze, E Gouze, C Pilapil, SC Ghivizzani, CH Evans, MM Murray |
Molecular Therapy | 2004 |
|
Bone Morphogenetic Protein–7 (Osteogenic Protein–1) Promotes Tendon Graft Integration in Anterior Cruciate Ligament Reconstruction in Sheep
R Mihelic, M Pecina, M Jelic, S Zoricic, V Kusec, P Simic, D Bobinac, B Lah, D Legovic, S Vukicevic |
The American journal of sports medicine | 2004 |
|
Bone Morphogenetic Proteins: Regeneration of Bone and Beyond
S Vukicevic, KT Sampath |
2004 | |
|
HtrA1 serine protease inhibits signaling mediated by Tgfβ family proteins
C Oka, R Tsujimoto, M Kajikawa, K Koshiba-Takeuchi, J Ina, M Yano, A Tsuchiya, Y Ueta, A Soma, H Kanda, M Matsumoto, M Kawaichi |
Development (Cambridge, England) | 2004 |
|
Gene transfer to the tendon-bone insertion site
C Lattermann, BA Zelle, JD Whalen, AW Baltzer, PD Robbins, C Niyibizi, CH Evans, FH Fu |
Knee Surgery, Sports Traumatology, Arthroscopy | 2004 |
|
GDF-5 deficiency in mice delays Achilles tendon healing
A Chhabra, D Tsou, RT Clark, V Gaschen, EB Hunziker, B Mikic |
Journal of Orthopaedic Research | 2003 |
|
A comparative dose–response study of cartilage-derived morphogenetic protein (CDMP)-1, -2 and -3 for tendon healing in rats
C Forslund, D Rueger, P Aspenberg |
Journal of Orthopaedic Research | 2003 |
|
In situ gene transfer into animal tendons by injection of naked DNA and electrotransfer
M Jayankura, C Boggione, C Fris�n, O Boyer, P Fouret, G Saillant, D Klatzmann |
The Journal of Gene Medicine | 2003 |
|
Tissue-Engineering Approach to the Repair and Regeneration of Tendons and Ligaments
JC Goh, HW Ouyang, SH Teoh, CK Chan, EH Lee |
Tissue Engineering | 2003 |
|
BMP treatment for improving tendon repair
C Forslund |
Acta Orthopaedica | 2003 |
|
Cartilage morphogenetic proteins: role in joint development, homoeostasis, and regeneration
AH Reddi |
Annals of the rheumatic diseases | 2003 |
|
A general approach for identifying distant regulatory elements applied to the Gdf6 gene
DP Mortlock, C Guenther, DM Kingsley |
Genome research | 2003 |
|
Animal models of inflammatory spinal and sacroiliac joint diseases
Y Zhang |
Rheumatic Disease Clinics of North America | 2003 |
|
Multiple joint and skeletal patterning defects caused by single and double mutations in the mouse Gdf6 and Gdf5 genes
SH Settle, RB Rountree, A Sinha, A Thacker, K Higgins, DM Kingsley |
Developmental Biology | 2003 |
|
The roles of bone morphogenetic protein (BMP) 12 in stimulating the proliferation and matrix production of human patellar tendon fibroblasts
SC Fu, YP Wong, BP Chan, HM Pau, YC Cheuk, KM Lee, KM Chan |
Life Sciences | 2003 |
|
Functional role of growth/differentiation factor 5 in chondrogenesis of limb mesenchymal cells
CM Coleman, RS Tuan |
Mechanisms of Development | 2003 |
|
Controlling mesenchymal stem cell differentiation by TGFβ family members
BA Roelen, P Dijke |
Journal of Orthopaedic Science | 2003 |
|
Correlation of GDF5 and connexin 43 mRNA expression during embryonic development
CM Coleman, GA Loredo, CW Lo, RS Tuan |
The Anatomical Record | 2003 |
|
Effects of osteogenic protein-1 (OP-1, BMP-7) on gene expression in cultured medial collateral ligament cells
AD Tsai, LC Yeh, JC Lee |
Journal of Cellular Biochemistry | 2003 |
|
Osteogenic potential of five different recombinant human bone morphogenetic protein adenoviral vectors in the rat
JZ Li, H Li, T Sasaki, D Holman, B Beres, RJ Dumont, DD Pittman, GR Hankins, GA Helm |
Gene Therapy | 2003 |
|
BMP-2-induced Runx2 Expression Is Mediated by Dlx5, and TGF-β1 Opposes the BMP-2-induced Osteoblast Differentiation by Suppression of Dlx5 Expression
MH Lee, YJ Kim, HJ Kim, HD Park, AR Kang, HM Kyung, JH Sung, JM Wozney, HJ Kim, HM Ryoo |
The Journal of biological chemistry | 2003 |
|
Gene Expression of Growth Differentiation Factors in the Developing Periodontium of Rat Molars
K Sena, Y Morotome, O Baba, T Terashima, Y Takano, I Ishikawa |
Journal of dental research | 2003 |
|
Improved Healing of Transected Rabbit Achilles Tendon after a Single Injection of Cartilage-Derived Morphogenetic Protein-2
C Forslund, P Aspenberg |
The American journal of sports medicine | 2003 |
|
Characteristics of periodontal ligament and regeneration of periodontal tissue
S Kasugai |
Ensho Saisei | 2003 |
|
Two endothelin 1 effectors, hand2 and bapx1 ,pattern ventral pharyngeal cartilage and the jaw joint
CT Miller, D Yelon, DY Stainier, CB Kimmel |
Development (Cambridge, England) | 2003 |
|
Effects of growth/differentiation factor-5 on human periodontal ligament cells: Effects of rhGDF-5 on HPDL
T Nakamura, M Yamamoto, M Tamura, Y Izumi |
Journal of Periodontal Research | 2003 |
|
Temporal expression of fibroblast growth factor receptors during primary ligament repair
SM Cool, CP Snyman, V Nurcombe, M Forwood |
Knee Surgery, Sports Traumatology, Arthroscopy | 2003 |
|
Imparting bone affinity to glycoproteins through the conjugation of bisphosphonates
Sébastien A Gittens, John R Matyas, Ronald F Zernicke, Hasan Uludağ |
Pharmaceutical Research | 2003 |
|
Overview of Bone Morphogenetic Proteins
JM Wozney |
Spine | 2002 |
|
CDMP-2 induces bone or tendon-like tissue depending on mechanical stimulation
C Forslund, P Aspenberg |
Journal of Orthopaedic Research | 2002 |
|
The localized expression of extracellular matrix components in healing tendon insertion sites: an in situ hybridization study
S Thomopoulos, G Hattersley, V Rosen, M Mertens, L Galatz, GR Williams, LJ Soslowsky |
Journal of Orthopaedic Research | 2002 |
|
The effect of growth/differentiation factor-5 deficiency on femoral composition and mechanical behavior in mice
B Mikic, TC Battaglia, EA Taylor, RT Clark |
Bone | 2002 |
|
Adult mesenchymal stem cells and cell-based tissue engineering
RS Tuan, G Boland, R Tuli |
Arthritis Research & Therapy | 2002 |
|
Studies on the Role of Cux1 in Regulation of the Onset of Joint Formation in the Developing Limb
G Lizarraga, A Lichtler, WB Upholt, RA Kosher |
Developmental Biology | 2002 |
|
Activation of Cartilage-Derived Morphogenetic Protein-1 in Torn Rotator Cuff:
T Nakase, K Sugamoto, T Miyamoto, N Tsumaki, FP Luyten, H Inui, A Myoui, T Tomita, H Yoshikawa |
Clinical Orthopaedics and Related Research® | 2002 |
|
Genetic Analysis of the Mammalian Transforming Growth Factor-β Superfamily
H Chang, CW Brown, MM Matzuk |
Endocrine reviews | 2002 |
|
Bone Morphogenetic Proteins
S Vukicevic, KT Sampath |
2002 | |
|
Bone Morphogenetic Proteins: From Laboratory to Clinical Practice
S Vukicevic, KT Sampath |
2002 | |
|
The life cycle of chondrocytes in the developing skeleton
L Shum, G Nuckolls |
Arthritis research | 2001 |
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BMP-12 gene transfer augmentation of lacerated tendon repair
J Lou, Y Tu, M Burns, MJ Silva, P Manske |
Journal of Orthopaedic Research | 2001 |
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A light and electron microscopic study of ectopic tendon and ligament formation induced by bone morphogenetic protein—13 adenoviral gene therapy
GA Helm, JZ Li, TD Alden, SB Hudson, EJ Beres, M Cunningham, MM Mikkelsen, DD Pittman, KM Kerns, DF Kallmes |
Journal of Neurosurgery | 2001 |
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Growth/differentiation factor 7 is preferentially expressed in the primary motor area of the monkey neocortex
A Watakabe, H Fujita, M Hayashi, T Yamamori |
Journal of Neurochemistry | 2001 |
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GDF-5 Deficiency in Mice Leads to Disruption of Tail Tendon Form and Function
RT Clark, TL Johnson, BJ Schalet, L Davis, V Gaschen, EB Hunziker, Å Oldberg, B Mikic |
Connective Tissue Research | 2001 |
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Wnt-14 Plays a Pivotal Role in Inducing Synovial Joint Formation in the Developing Appendicular Skeleton
C Hartmann, CJ Tabin |
Cell | 2001 |
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The BMP Family Member Gdf7 Is Required for Seminal Vesicle Growth, Branching Morphogenesis, and Cytodifferentiation
S Settle, P Marker, K Gurley, A Sinha, A Thacker, Y Wang, K Higgins, G Cunha, DM Kingsley |
Developmental Biology | 2001 |
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The molecular control of upper extremity development: Implications for congenital hand anomalies
A Daluiski, SE Yi, KM Lyons |
The Journal of Hand Surgery | 2001 |
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The anterior cruciate ligament — current concepts
RL Allum |
The Knee | 2001 |
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Bone morphogenetic proteins in the development and healing of synovial joints
CJ Edwards, PH Francis-West |
Seminars in Arthritis and Rheumatism | 2001 |
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A Growth and Differentiation Factor-5 (GDF-5)-coated Suture Stimulates Tendon Healing in an Achilles Tendon Model in Rats
M Rickert, M Jung, M Adiyaman, W Richter, HG Simank |
Growth Factors | 2001 |
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Smad-interacting Protein 1 Is a Repressor of Liver/Bone/Kidney Alkaline Phosphatase Transcription in Bone Morphogenetic Protein-induced Osteogenic Differentiation of C2C12 Cells
P Tylzanowski, K Verschueren, D Huylebroeck, FP Luyten |
The Journal of biological chemistry | 2001 |
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The Art of Making a Joint
F Spitz, D Duboule |
Science | 2001 |
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Synergistic effects of different bone morphogenetic protein type I receptors on alkaline phosphatase induction
H Aoki, M Fujii, T Imamura, K Yagi, K Takehara, M Kato, K Miyazono |
Journal of cell science | 2001 |
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A light and electron microscopic study of ectopic tendon and ligament formation induced by bone morphogenetic protein–13 adenoviral gene therapy
GA Helm, JZ Li, TD Alden, SA Hudson, EJ Beres, M Cunningham, MM Mikkelsen, DD Pittman, KM Kerns, DF Kallmes |
Neurosurgical FOCUS | 2000 |
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The family of bone morphogenetic proteins
P Ducy, G Karsenty |
Kidney International | 2000 |
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Bone Morphogenetic Proteins and Bone Morphogenetic Protein Gene Therapy in Neurological Surgery: A Review
GA Helm, TD Alden, JP Sheehan, D Kallmes |
Neurosurgery | 2000 |
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Extracellular Matrix Modulation of rhGDF-5-Induced Cellular Differentiation
MA Heidaran, R Daverman, A Thompson, CK Ng, J Pohl, JW Poser, RC Spiro |
e-biomed: The Journal of Regenerative Medicine | 2000 |
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Implantation of recombinant human bone morphogenetic proteins with biomaterial carriers: A correlation between protein pharmacokinetics and osteoinduction in the rat ectopic model
H Uludag, D D'Augusta, J Golden, J Li, G Timony, R Riedel, JM Wozney |
Journal of Biomedical Materials Research | 2000 |
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The pro-alpha3(V) collagen chain. Complete primary structure, expression domains in adult and developing tissues, and comparison to the structures and expression domains of the other types V and XI procollagen chains
Y Imamura, IC Scott, DS Greenspan |
The Journal of biological chemistry | 2000 |
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TISSUE-ENGINEERED LIGAMENT
JA Koski, C Ibarra, SA Rodeo |
Orthopedic Clinics of North America | 2000 |
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Biological Repair of Thyroid Cartilage Defects by Osteogenic Protein-1 (Bone Morphogenetic Protein-7) in Dog
V Katic, L Majstorovic, D Maticic, B Pirkic, S Yin, J Kos, S Martinovic, JE McCartney, S Vukicevic |
Growth Factors | 2000 |
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Injury and Repair of Tendons and Ligaments
J Hyman, SA Rodeo |
Physical medicine and rehabilitation clinics of North America | 2000 |
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Gene Therapy and Tissue Engineering in Orthopaedic and Sports Medicine
J Huard, FH Fu |
2000 | |
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Use of porous hydroxyapatite graft containing recombinant human bone morphogenetic protein-2 for cervical fusion in a caprine model
T Takahashi, T Tominaga, N Watabe, AT Yokobori, H Sasada, T Yoshimoto |
Journal of Neurosurgery: Spine | 1999 |
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Enhanced tendon healing with GDF 5 and 6
P Aspenberg, C Forslund |
Acta Orthopaedica | 1999 |
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Axis development: The mouse becomes a dachshund
JM Gad, PP Tam |
Current Biology | 1999 |
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GDF5 Coordinates Bone and Joint Formation during Digit Development
EE Storm, DM Kingsley |
Developmental Biology | 1999 |
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Expression and Function ofGdf-5during Digit Skeletogenesis in the Embryonic Chick Leg Bud
R Merino, D Macias, Y Gañan, AN Economides, X Wang, Q Wu, N Stahl, KT Sampath, P Varona, JM Hurle |
Developmental Biology | 1999 |
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Anterior cruciate ligament reconstruction using quadruple hamstring
FH Fu, C Benjamin |
Operative techniques in orthopaedics | 1999 |
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Different Effects of Bone Morphogenetic Proteins 2, 4, 12, and 13 on the Expression of Cartilage and Bone Markers in the MC615 Chondrocyte Cell Line
U Valcourt, MC Ronzière, P Winkler, V Rosen, D Herbage, F Mallein-Gerin |
Experimental Cell Research | 1999 |
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BMP Receptors in Limb and Tooth Formation
S Cheifetz |
Critical Reviews in Oral Biology & Medicine | 1999 |
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Current Trends in Anterior Cruciate Ligament Reconstruction
FH Fu, CH Bennett, C Lattermann, CB Ma |
The American journal of sports medicine | 1999 |
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Roles of Bone Morphogenetic Protein Type I Receptors and Smad Proteins in Osteoblast and Chondroblast Differentiation
M Fujii, K Takeda, T Imamura, H Aoki, TK Sampath, S Enomoto, M Kawabata, M Kato, H Ichijo, K Miyazono, M Raff |
Molecular biology of the cell | 1999 |
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Effect of Bone Morphogenetic Protein-12 Gene Transfer on Mesenchymal Progenitor Cells:
J Lou, Y Tu, FJ Ludwig, J Zhang, PR Manske |
Clinical Orthopaedics and Related Research® | 1999 |
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Mechanisms of GDF-5 action during skeletal development
PH Francis-West, A Abdelfattah, P Chen, C Allen, J Parish, R Ladher, S Allen, S MacPherson, FP Luyten, CW Archer |
Development (Cambridge, England) | 1999 |
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Cytokines and the Role They Play in the Healing of Ligaments and Tendons:
CH Evans |
Sports Medicine | 1999 |
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Cartilage-derived morphogenetic proteins and cartilage morphogenesis
AH Reddi |
Microscopy Research and Technique | 1998 |
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Signal transduction by bone morphogenetic proteins
M Kawabata |
Cytokine & Growth Factor Reviews | 1998 |
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Bone Morphogenetic Proteins: From Basic Studies to Clinical Approaches
T Sakou |
Bone | 1998 |
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OP-1 has more effect than mechanical signals in the control of tissue differentiation in healing rat tendons
C Forslund, P Aspenberg |
Acta Orthopaedica | 1998 |
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Advances in Protein Chemistry
CM Silva, J Isgaard, MO Thorner |
Advances in Protein Chemistry | 1998 |
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Gene Expression of Growth and Differentiation Factors-5, -6, and -7 in Developing Bovine Tooth at the Root Forming Stage
Y Morotome, M Goseki-Sone, I Ishikawa, S Oida |
Biochemical and Biophysical Research Communications | 1998 |
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The Bone Morphogenetic Protein 15 Gene Is X-Linked and Expressed in Oocytes
JL Dube, P Wang, J Elvin, KM Lyons, AJ Celeste, MM Matzuk |
Molecular Endocrinology | 1998 |
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