JCI - Citations to Therapeutic potential of inhibition of the NF-κB pathway in the treatment of inflammation and cancer

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Therapeutic potential of inhibition of the NF-κB pathway in the treatment of inflammation and cancer

Yumi Yamamoto, Richard B. Gaynor

Yumi Yamamoto, Richard B. Gaynor

Published January 15, 2001
Citation Information: J Clin Invest. 2001;107(2):135-142. https://doi.org/10.1172/JCI11914.

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Acylpolyamine Mygalin as a TLR4 Antagonist Based on Molecular Docking and In Vitro Analyses Espinoza-Culupú A, Vázquez-Ramírez R, Farfán-López M, Mendes E, Notomi Sato M, da Silva Junior PI, Borges MM	Biomolecules	2020
Citrus Peel Flavonoids as Potential Cancer Prevention Agents Koolaji N, Shammugasamy B, Schindeler A, Dong Q, Dehghani F, Valtchev P		2020
Anti-Inflammatory and Chondroprotective Effects of Vanillic Acid and Epimedin C in Human Osteoarthritic Chondrocytes Ziadlou R, Barbero A, Martin I, Wang X, Qin L, Alini M, Grad S	Biomolecules	2020
Studies on the Mechanisms of Anti-Inflammatory Activity of Heparin- and Hyaluronan-Containing Multilayer Coatings—Targeting NF-κB Signalling Pathway Alkhoury H, Hautmann A, Fuhrmann B, Syrowatka F, Erdmann F, Zhou G, Stojanović S, Najman S, Groth T	International journal of molecular sciences	2020
Age-related inflammation triggers skeletal stem/progenitor cell dysfunction AM Josephson, V Bradaschia-Correa, S Lee, K Leclerc, KS Patel, EM Lopez, HP Litwa, SS Neibart, M Kadiyala, MZ Wong, MM Mizrahi, NL Yim, AJ Ramme, KA Egol, P Leucht	Proceedings of the National Academy of Sciences	2019
Attenuation of NF‐κB in intestinal epithelial cells is sufficient to mitigate the bone loss co‐morbidity of experimental mouse colitis K Ke, TH Chen, M Arra, G Mbalaviele, G Swarnkar, Y AbuAmer	Journal of Bone and Mineral Research	2019
(5R)-5-hydroxytriptolide inhibits the inflammatory cascade reaction in astrocytes YQ Cui, Y Zheng, GL Tan, DM Zhang, JY Wang, XM Wang	NEURAL REGEN RES	2019
Mechanisms of Acupuncture Therapy for Simple Obesity: An Evidence-Based Review of Clinical and Animal Studies on Simple Obesity LH Wang, W Huang, D Wei, DG Ding, YR Liu, JJ Wang, ZY Zhou	Evidence-Based Complementary and Alternative Medicine	2019
The Selection of NFκB Inhibitors to Block Inflammation and Induce Sensitisation to FasL-Induced Apoptosis in HNSCC Cell Lines Is Critical for Their Use as a Prospective Cancer Therapy M Scheurer, R Brands, M El-Mesery, S Hartmann, U Müller-Richter, A Kübler, A Seher	International journal of molecular sciences	2019
miR-135 regulated breast cancer proliferation and epithelial-mesenchymal transition acts by the Wnt/β-catenin signaling pathway D Jiang, B Zhou, Y Xiong, H Cai	International journal of molecular medicine	2019
Influence of Resveratrol on the Immune Response Malaguarnera	Nutrients	2019
Glucocorticoids—All-Rounders Tackling the Versatile Players of the Immune System C Strehl, L Ehlers, T Gaber, F Buttgereit	Frontiers in immunology	2019
BAFF/APRIL System Is Functional in B-Cell Acute Lymphoblastic Leukemia in a Disease Subtype Manner E Sevdali, E Katsantoni, CR Smulski, M Moschovi, M Palassopoulou, EN Kolokotsa, N Argentou, N Giannakoulas, M Adamaki, G Vassilopoulos, S Polychronopoulou, AE Germenis, H Eibel, M Speletas	Frontiers in Oncology	2019
PPARα serves as a new receptor of aspirin for neuroprotection D Patel, A Roy, K Pahan	Journal of Neuroscience Research	2019
Effects of Propolis Extract and Propolis-Derived Compounds on Obesity and Diabetes: Knowledge from Cellular and Animal Models Kitamura	Molecules (Basel, Switzerland)	2019
Dysregulation of Cell Death in Human Chronic Inflammation Y Li, C Klein, D Kotlarz	Cold Spring Harbor perspectives in biology	2019
Nonsteroidal Anti-Inflammatory Drugs: A Potential Pharmacological Treatment for Intracranial Aneurysm CL Fisher, SL Demel	Cerebrovascular Diseases Extra	2019
Silibinin attenuates high-fat diet-induced renal fibrosis of diabetic nephropathy K Liu, S Zhou, J Liu, Y Wang, F Zhu, M Liu	Drug design, development and therapy	2019
Anti-Inflammatory Activities of Isogosferol, a Furanocoumarin Isolated from Citrus junos Seed Shells through Bioactivity-Guided Fractionation Song HY, Jo A, Shin J, Lim EH, Lee YE, Jeong DE, Lee M	Molecules (Basel, Switzerland)	2019
Non-SMC condensin I complex subunit D2 and non-SMC condensin II complex subunit D3 induces inflammation via the IKK/NF-κB pathway in ulcerative colitis Yuan CW, Sun XL, Qiao LC, Xu HX, Zhu P, Chen HJ, Yang BL	World Journal of Gastroenterology	2019
Deoxynivalenol Induces Inflammatory Injury in IPEC-J2 Cells via NF-κB Signaling Pathway Wang X, Zhang Y, Zhao J, Cao L, Zhu L, Huang Y, Chen X, Rahman SU, Feng S, Li Y, Wu J	Toxins	2019
Effects of dietary Antrodia cinnamomea fermented product supplementation on metabolism pathways of antioxidant, inflammatory, and lipid metabolism pathways-a potential crosstalk Lee MT, Lin WC, Lin LJ, Wang SY, Chang SC, Lee TT	Asian-Australasian Journal of Animal Sciences	2019
5-Hydroxymethylfurfural Mitigates Lipopolysaccharide-Stimulated Inflammation via Suppression of MAPK, NF-κB and mTOR Activation in RAW 264.7 Cells Kong F, Lee BH, Wei K	Molecules (Basel, Switzerland)	2019
Cryptotanshinone Attenuates Inflammatory Response of Microglial Cells via the Nrf2/HO-1 Pathway Zhou Y, Wang X, Ying W, Wu D, Zhong P	Frontiers in neuroscience	2019
Synthesis of novel 4-Boc-piperidone chalcones and evaluation of their cytotoxic activity against highly-metastatic cancer cells Ocasio-Malavé C, Donate MJ, Sánchez MM, Sosa-Rivera JM, Mooney JW, Pereles-De León TA, Carballeira NM, Zayas B, Vélez-Gerena CE, Martínez-Ferrer M, Sanabria-Ríos DJ	Bioorganic & Medicinal Chemistry Letters	2019
Saikosaponin B2 Suppresses Inflammatory Responses Through IKK/IκBα/NF-κB Signaling Inactivation in LPS-Induced RAW 264.7 Macrophages. Shin JS, Im HT, Lee KT	Inflammation	2019
Aspirin binds to PPARα to stimulate hippocampal plasticity and protect memory D Patel, A Roy, M Kundu, M Jana, CH Luan, FJ Gonzalez, K Pahan	Proceedings of the National Academy of Sciences	2018
Regulation of breast cancer induced bone disease by cancer-specific IKKβ S Marino, RT Bishop, M Capulli, A Sophocleous, JG Logan, P Mollat, B Mognetti, L Ventura, AH Sims, N Rucci, SH Ralston, AI Idris	Oncotarget	2018
Adenine attenuates lipopolysaccharide-induced inflammatory reactions P Silwal, K Lim, JY Heo, JI Park, U Namgung, SK Park	The Korean Journal of Physiology & Pharmacology	2018
Immunological Approaches Towards Cancer and Inflammation: A Cross Talk X Qu, Y Tang, S Hua	Frontiers in immunology	2018
Galectin-3 activates TLR4/NF-κB signaling to promote lung adenocarcinoma cell proliferation through activating lncRNA-NEAT1 expression W Zhou, X Chen, Q Hu, X Chen, Y Chen, L Huang	BMC Cancer	2018
Human NF-κB1 Haploinsufficiency and Epstein–Barr Virus-Induced Disease—Molecular Mechanisms and Consequences B Hoeger, NK Serwas, K Boztug	Frontiers in immunology	2018
Mechanisms of Phytonutrient Modulation of Cyclooxygenase-2 (COX-2) and Inflammation Related to Cancer SJ Desai, B Prickril, A Rasooly	Nutrition and Cancer	2018
Gene expression profiling of breast cancer cell lines treated with proton and electron radiations V Bravatà, L Minafra, FP Cammarata, P Pisciotta, D Lamia, V Marchese, G Petringa, L Manti, GA Cirrone, MC Gilardi, G Cuttone, GI Forte, G Russo	British Journal of Radiology	2018
Tumor necrosis factor alpha reduces intestinal vitamin C uptake: a role for NF-κB-mediated signaling VS Subramanian, S Sabui, GA Subramenium, JS Marchant, HM Said	AJP Gastrointestinal and Liver Physiology	2018
Anti-Inflammatory Effect of Melittin on Porphyromonas Gingivalis LPS-Stimulated Human Keratinocytes WH Kim, HJ An, JY Kim, MG Gwon, H Gu, M Jeon, MK Kim, SM Han, KK Park	Molecules (Basel, Switzerland)	2018
Modeling the therapeutic efficacy of NFκB synthetic decoy oligodeoxynucleotides (ODNs) Z Wang, DA Potoyan, PG Wolynes	BMC Systems Biology	2018
Biological Activities and Potential Oral Applications of N-Acetylcysteine: Progress and Prospects Y Pei, H Liu, Y Yang, Y Yang, Y Jiao, FR Tay, J Chen	Oxidative medicine and cellular longevity	2018
Radiation-Induced Endothelial Vascular Injury BP Venkatesulu, LS Mahadevan, ML Aliru, , MH Bodd, PK Singh, SW Yusuf, J Abe, S Krishnan	JACC: Basic to Translational Science	2018
The inhibitory effects of plumbagin on the NF-қB pathway and CCL2 release in racially different triple-negative breast cancer cells SS Messeha, NO Zarmouh, P Mendonca, H Alwagdani, MG Kolta, KF Soliman, A Ahmad	PloS one	2018
Novel TNF receptor-1 inhibitors identified as potential therapeutic candidates for traumatic brain injury RK Rowe, JL Harrison, H Zhang, AD Bachstetter, DP Hesson, BF OHara, MI Greene, J Lifshitz	Journal of Neuroinflammation	2018
Prepartum fatty acid supplementation in sheep. II. Supplementation of eicosapentaenoic acid and docosahexaenoic acid during late gestation alters the fatty acid profile of plasma, colostrum, milk and adipose tissue, and increases lipogenic gene expression of adipose tissue1 DN Coleman, KD Murphy, AE Relling	Journal of animal science	2018
Crude leaf extracts of Piperaceae species downmodulate inflammatory responses by human monocytes AC Finato, TF Fraga-Silva, AU Prati, AA de Souza Júnior, BF Mazzeu, LG Felippe, RA Pinto, M de Assis Golim, MS Arruda, M Furlan, J Venturini, KE Peterson	PloS one	2018
Suppression of the NF‑κB signaling pathway in colon cancer cells by the natural compound Riccardin D from Dumortierahirsute H Liu, G Li, B Zhang, D Sun, J Wu, F Chen, F Kong, Y Luan, W Jiang, R Wang, X Xue	Molecular medicine reports	2018
NF-κB p65 and p105 implicate in interleukin 1β-mediated COX-2 expression in melanoma cells N Kitanaka, R Nakano, T Kitanaka, S Namba, T Konno, T Nakayama, H Sugiya, CM Yang	PloS one	2018
Anti-Inflammatory Effects of Aster incisus through the Inhibition of NF- κ B, MAPK, and Akt Pathways in LPS-Stimulated RAW 264.7 Macrophages D Ngabire, YA Seong, MP Patil, I Niyonizigiye, YB Seo, GD Kim	Mediators of Inflammation	2018
Smad7 Promotes Healing of Radiotherapy-Induced Oral Mucositis without Compromising Oral Cancer Therapy in a Xenograft Mouse Model J Luo, L Bian, MA Blevins, D Wang, C Liang, D Du, F Wu, B Holwerda, R Zhao, D Raben, H Zhou, CD Young, XJ Wang	Clinical cancer research	2018
Tetrandrine suppresses adhesion, migration and invasion of human colon cancer SW620 cells via inhibition of nuclear factor-κB, matrix metalloproteinase-2 and matrix metalloproteinase-9 signaling pathways TK Juan, KC Liu, CL Kuo, MD Yang, YL Chu, JL Yang, PP Wu, YP Huang, KC Lai, JG Chung	Oncology Letters	2018
N-Substituted Pyrido-1,4-Oxazin-3-Ones Induce Apoptosis of Hepatocellular Carcinoma Cells by Targeting NF-κB Signaling Pathway. Mohan CD, Bharathkumar H, Dukanya, Rangappa S, Shanmugam MK, Chinnathambi A, Alharbi SA, Alahmadi TA, Bhattacharjee A, Lobie PE, Deivasigamani A, Hui KM, Sethi G, Basappa, Rangappa KS, Kumar AP	Frontiers in pharmacology	2018
Repurposing Thioridazine (TDZ) as an anti-inflammatory agent Baig MS, Roy A, Saqib U, Rajpoot S, Srivastava M, Naim A, Liu D, Saluja R, Faisal SM, Pan Q, Turkowski K, Darwhekar GN, Savai R	Scientific Reports	2018
Plant-Derived Products for Treatment of Vascular Intima Hyperplasia Selectively Inhibit Vascular Smooth Muscle Cell Functions Xu K, Al-ani MK, Pan X, Chi Q, Dong N, Qiu X	Evidence-based complementary and alternative medicine : eCAM	2018
Peiminine Protects against Lipopolysaccharide-Induced Mastitis by Inhibiting the AKT/NF-κB, ERK1/2 and p38 Signaling Pathways Gong Q, Li Y, Ma H, Guo W, Kan X, Xu D, Liu J, Fu S	International journal of molecular sciences	2018
Effects of Nonsteroidal Anti-Inflammatory Drugs at the Molecular Level Gunaydin C, Bilge SS	The Eurasian Journal of Medicine	2018
Ingenol-3-Angelate Suppresses Growth of Melanoma Cells and Skin Tumor Development by Downregulation of NF-κB-Cox2 Signaling Wang D, Liu P	Medical science monitor : international medical journal of experimental and clinical research	2018
Resveratrol decreases apoptosis and NLRP3 complex expressions in experimental varicocele rat model Hajipour E, Mashayekhi FJ, Mosayebi G, Baazm M, Zendedel A	Iranian Journal of Basic Medical Sciences	2018
Spilanthol Inhibits COX-2 and ICAM-1 Expression via Suppression of NF-κB and MAPK Signaling in Interleukin-1β-Stimulated Human Lung Epithelial Cells. Huang WC, Wu LY, Hu S, Wu SJ	Inflammation	2018
Annonaceae: Breaking the Wall of Inflammation A Attiq, J Jalil, K Husain	Frontiers in pharmacology	2017
Anti-Inflammatory Effects of Licochalcone A on IL-1β-Stimulated Human Osteoarthritis Chondrocytes T Jia, J Qiao, D Guan, T Chen	Inflammation	2017
Gamma-tocopherol supplementation ameliorated hyper-inflammatory response during the early cutaneous wound healing in alloxan-induced diabetic mice J Shin, SJ Yang, Y Lim	Experimental biology and medicine (Maywood, N.J.)	2017
Exploiting the Ref-1-APE1 node in cancer signaling and other diseases: from bench to clinic F Shah, D Logsdon, RA Messmann, JC Fehrenbacher, ML Fishel, MR Kelley	npj Precision Oncology	2017
Antidiabetic activities of polysaccharides separated from Inonotus obliquus via the modulation of oxidative stress in mice with streptozotocin-induced diabetes J Wang, W Hu, L Li, X Huang, Y Liu, D Wang, L Teng, MF Essop	PloS one	2017
Multi-Targeting Andrographolide, a Novel NF-κB Inhibitor, as a Potential Therapeutic Agent for Stroke CH Yang, TL Yen, CY Hsu, PA Thomas, JR Sheu, T Jayakumar	International journal of molecular sciences	2017
Tumor-related interleukins: old validated targets for new anti-cancer drug development S Setrerrahmane, H Xu	Molecular Cancer	2017
Protective Effects of Oral Astaxanthin Nanopowder against Ultraviolet-Induced Photokeratitis in Mice F Harada, T Morikawa, A Lennikov, A Mukwaya, M Schaupper, O Uehara, R Takai, K Yoshida, J Sato, Y Horie, H Sakaguchi, CZ Wu, Y Abiko, N Lagali, N Kitaichi	Oxidative medicine and cellular longevity	2017
Small molecule-mediated tribbles homolog 3 promotes bone formation induced by bone morphogenetic protein-2 J Fan, J Pi-Anfruns, M Guo, DC Im, ZK Cui, S Kim, BM Wu, TL Aghaloo, M Lee	Scientific Reports	2017
Bortezomib protects against dextran sulfate sodium-induced ulcerative colitis in mice LH Hu, YJ Fan, Q Li, JM Guan, B Qu, FH Pei, BR Liu	Molecular medicine reports	2017
Clinical Tolerogenic Dendritic Cells: Exploring Therapeutic Impact on Human Autoimmune Disease BE Phillips, Y Garciafigueroa, M Trucco, N Giannoukakis	Frontiers in immunology	2017
Inflammation and Epithelial-Mesenchymal Transition in Pancreatic Ductal Adenocarcinoma: Fighting Against Multiple Opponents M Khan, F Khalafalla	Cancer Growth and Metastasis	2017
An Exploration of Phytochemicals from Simaroubaceae Biba Vikas, B S Akhil, S R Suja, K Sujathan	Asian Pacific Journal of Cancer Prevention	2017
Treatment of Cyclosporin A retains host defense against invasive pulmonary aspergillosis in a non-immunosuppressive murine model by preserving the myeloid cell population SS Wong, O Rasid, P Laskaris, A Fekkar, JM Cavaillon, WJ Steinbach, O Ibrahim-Granet	Virulence	2017
Biochemical and clinical relevance of alpha lipoic acid: antioxidant and anti-inflammatory activity, molecular pathways and therapeutic potential. Tibullo D, Li Volti G, Giallongo C, Grasso S, Tomassoni D, Anfuso CD, Lupo G, Amenta F, Avola R, Bramanti V	Inflammation research : official journal of the European Histamine Research Society ... [et al.]	2017
Antioxidant activities of fresh grape juices prepared using various household processing methods Kim MJ, Jun JG, Park SY, Choi MJ, Park E, Kim JI, Kim MJ	Food Science and Biotechnology	2017
Schisandrol B and schisandrin B inhibit TGFβ1-mediated NF-κB activation via a Smad-independent mechanism Chun JN, Park S, Lee S, Kim JK, Park EJ, Kang M, Kim HK, Park JK, So I, Jeon JH	Oncotarget	2017
Strigolactones: a plant phytohormone as novel anti-inflammatory agents †Electronic supplementary information (ESI) available. See DOI: 10.1039/c7md00461c Zheng JX, Han YS, Wang JC, Yang H, Kong H, Liu KJ, Chen SY, Chen YR, Chang YQ, Chen WM, Guo JL, Sun PH	MedChemComm	2017
The Growth Inhibitory Potential and Antimetastatic Effect of Camel Urine on Breast Cancer Cells In Vitro and In Vivo F Romli, N Abu, FA Khorshid, SU Najmuddin, YS Keong, NE Mohamad, M Hamid, NB Alitheen, NM Rahman	Integrative Cancer Therapies	2016
Aspirin inhibits epithelial-to-mesenchymal transition and migration of oncogenic K-ras-expressing non-small cell lung carcinoma cells by down-regulating E-cadherin repressor Slug P Khan, A Manna, S Saha, S Mohanty, S Mukherjee, M Mazumdar, D Guha, T Das	BMC Cancer	2016
Effect of Thiol-reducing Agents and Antioxidants on Sulfasalazine-induced Hepatic Injury in Normotermic Recirculating Isolated Perfused Rat Liver R Heidari, N Esmailie, N Azarpira, A Najibi, H Niknahad	Toxicological Research	2016
Effect of intravitreal dexamethasone implant on retinal and choroidal thickness in refractory diabetic macular oedema after multiple anti-VEGF injections M Kim, YJ Cho, CH Lee, SC Lee	Eye	2016
The Effects of Ellagic Acid upon Brain Cells: A Mechanistic View and Future Directions MR de Oliveira	Neurochemical Research	2016
Snail-induced epithelial-to-mesenchymal transition of MCF-7 breast cancer cells: systems analysis of molecular changes and their effect on radiation and drug sensitivity R Mezencev, LV Matyunina, N Jabbari, JF McDonald	BMC Cancer	2016
Downstream activation of NF-κB in the EDA-A1/EDAR signalling in Sjögren's syndrome and its regulation by the ubiquitin-editing enzyme A20: EDA-A1/NF-κB signalling in Sjögren's syndrome M Sisto, A Barca, DD Lofrumento, S Lisi	Clinical & Experimental Immunology	2016
Trans-Cinnamaldehyde, An Essential Oil in Cinnamon Powder, Ameliorates Cerebral Ischemia-Induced Brain Injury via Inhibition of Neuroinflammation Through Attenuation of iNOS, COX-2 Expression and NFκ-B Signaling Pathway YF Chen, YW Wang, WS Huang, MM Lee, WG Wood, YM Leung, HY Tsai	NeuroMolecular Medicine	2016
MCAM, as a novel receptor for S100A8/A9, mediates progression of malignant melanoma through prominent activation of NF-κB and ROS formation upon ligand binding IM Ruma, EW Putranto, E Kondo, H Murata, M Watanabe, P Huang, R Kinoshita, J Futami, Y Inoue, A Yamauchi, IW Sumardika, C Youyi, KI Yamamoto, Y Nasu, M Nishibori, T Hibino, M Sakaguchi	Clinical & Experimental Metastasis	2016
Anti-HMG-CoA Reductase, Antioxidant, and Anti-Inflammatory Activities of Amaranthus viridis Leaf Extract as a Potential Treatment for Hypercholesterolemia S Salvamani, B Gunasekaran, MY Shukor, NA Shaharuddin, MK Sabullah, SA Ahmad	Evidence-Based Complementary and Alternative Medicine	2016
Analysis of cultivable microbiota and diet intake pattern of the long-lived naked mole-rat T Debebe, S Holtze, M Morhart, TB Hildebrandt, S Rodewald, K Huse, M Platzer, D Wyohannes, S Yirga, A Lemma, R Thieme, B König, G Birkenmeier	Gut pathogens	2016
A genetically encoded bioluminescent indicator for illuminating proinflammatory cytokines SB Kim, T Ozawa, Y Umezawa	MethodsX	2016
Role of nitric oxide in the pathogenesis of Barrett’s-associated carcinogenesis G Kusaka	World journal of gastrointestinal pathophysiology	2016
Assessment of Phenolic Compounds and Anti-Inflammatory Activity of Ethyl Acetate Phase of Anacardium occidentale L. Bark M Vilar, G Souza, D Vilar, J Leite, F Raffin, J Barbosa-Filho, F Nogueira, S Rodrigues-Mascarenhas, T Moura	Molecules (Basel, Switzerland)	2016
Molecular stripping, targets and decoys as modulators of oscillations in the NF-κB/IκBα/DNA genetic network Z Wang, DA Potoyan, PG Wolynes	Journal of The Royal Society Interface	2016
The COX- inhibitor indomethacin reduces Th1 effector and T regulatory cells in vitro in Mycobacterium tuberculosis infection K Tonby, I Wergeland, NV Lieske, D Kvale, K Tasken, AM Dyrhol-Riise	BMC Infectious Diseases	2016
Leucine Zipper Down-regulated in Cancer-1 (LDOC1) interacts with Guanine nucleotide binding protein-like 3-like (GNL3L) to modulate Nuclear Factor-kappa B (NF-κB) signaling during cell proliferation IJ Thoompumkal, K Rehna, K Anbarasu, S Mahalingam	Cell cycle (Georgetown, Tex.)	2016
Phycocyanin Inhibits Tumorigenic Potential of Pancreatic Cancer Cells: Role of Apoptosis and Autophagy G Liao, B Gao, Y Gao, X Yang, X Cheng, Y Ou	Scientific Reports	2016
HMGB1 translocation and release mediate cigarette smoke–induced pulmonary inflammation in mice through a TLR4/MyD88-dependent signaling pathway Y Cheng, D Wang, B Wang, H Li, J Xiong, S Xu, Q Chen, K Tao, X Yang, Y Zhu, S He, K Luo	Molecular biology of the cell	2016
The C-terminus of IGFBP-5 suppresses tumor growth by inhibiting angiogenesis JR Hwang, YJ Cho, Y Lee, Y Park, HD Han, HJ Ahn, JH Lee, JW Lee	Scientific Reports	2016
Anti-Inflammatory Effects of Protein Kinase Inhibitor Pyrrol Derivate HM Kuznietsova, MS Yena, IP Kotlyar, OV Ogloblya, VK Rybalchenko	The Scientific World JOURNAL	2016
The tri-peptide GHK-Cu complex ameliorates lipopolysaccharide-induced acute lung injury in mice JR Park, H Lee, SI Kim, SR Yang	Oncotarget	2016
DHA blocks TPA-induced cell invasion by inhibiting MMP-9 expression via suppression of the PPAR‑γ/NF-κB pathway in MCF-7 cells JK Hwang, HN Yu, EM Noh, JM Kim, OY Hong, H Youn, S Jung, KB Kwon, JS Kim, YR Lee	Oncology Letters	2016
Anti-inflammatory effect of birsonimadiol from seeds of Byrsonima crassifolia Pérez Gutiérrez RM	Food Science and Biotechnology	2016
Targeting IL-17B-IL-17RB signaling with an anti-IL-17RB antibody blocks pancreatic cancer metastasis by silencing multiple chemokines HH Wu, WW Hwang-Verslues, WH Lee, CK Huang, PC Wei, CL Chen, JY Shew, EY Lee, YM Jeng, YW Tien, C Ma, WH Lee	Journal of Experimental Medicine	2015
The importance of antioxidants which play the role in cellular response against oxidative/nitrosative stress: current state EB Kurutas	Nutrition Journal	2015
Pentacyclic Triterpenoids Inhibit IKKβ Mediated Activation of NF-κB Pathway: In Silico and In Vitro Evidences KR Patil, P Mohapatra, HM Patel, SN Goyal, S Ojha, CN Kundu, CR Patil, S Gautam	PloS one	2015
Therapeutic potential of caffeic acid phenethyl ester and its anti-inflammatory and immunomodulatory effects (Review) F Armutcu, S Akyol, S Ustunsoy, F Turan	Experimental and therapeutic medicine	2015
Electroacupuncture prevents white adipose tissue inflammation through modulation of hypoxia-inducible factors-1α-dependent pathway in obese mice CK Wen, TY Lee	BMC complementary and alternative medicine	2015
Increased extracellular pressure stimulates tumor proliferation by a mechanosensitive calcium channel and PKC-β MD Basson, B Zeng, C Downey, MP Sirivelu, JJ Tepe	Molecular Oncology	2015
Small molecule growth inhibitors of human oncogenic gammaherpesvirus infected B-cells RK Dzeng, HC Jha, J Lu, A Saha, S Banerjee, ES Robertson	Molecular Oncology	2015
Portrait of inflammatory response to ionizing radiation treatment FM di Maggio, L Minafra, GI Forte, FP Cammarata, D Lio, C Messa, MC Gilardi, V Bravatà	Journal of Inflammation	2015
Neuroinflammation in Alzheimer’s disease F Zhang, LL Jiang	Neuropsychiatric Disease and Treatment	2015
Quercetin Down-regulates IL-6/STAT-3 Signals to Induce Mitochondrial-mediated Apoptosis in a Nonsmall- cell Lung-cancer Cell Line, A549 A Mukherjee, AR Khuda-Bukhsh	Journal of Pharmacopuncture	2015
Synthesis of novel C5-curcuminoid-fatty acid conjugates and mechanistic investigation of their anticancer activity DJ Sanabria-Ríos, Y Rivera-Torres, J Rosario, C Ríos, R Gutierrez, NM Carballeira, C Vélez, B Zayas, F Álvarez-Colón, G Ortiz-Soto, V Serrano, J Altieri-Rivera, E Ríos-Olivares, JW Rodríguez	Bioorganic & Medicinal Chemistry Letters	2015
Inhibition of Inflammatory Arthritis Using Fullerene Nanomaterials AL Dellinger, P Cunin, D Lee, AL Kung, DB Brooks, Z Zhou, PA Nigrovic, CL Kepley, O Frey	PloS one	2015
Neuroprotective Effect of Neuroserpin in Oxygen-Glucose Deprivation- and Reoxygenation-Treated Rat Astrocytes In Vitro L Wang, Y Zhang, T Asakawa, W Li, S Han, Q Li, B Xiao, H Namba, C Lu, Q Dong, CM Norris	PloS one	2015
Apigenin Restricts FMDV Infection and Inhibits Viral IRES Driven Translational Activity S Qian, W Fan, P Qian, D Zhang, Y Wei, H Chen, X Li	Viruses	2015
Anti-Inflammatory and Analgesic Effects of the Marine-Derived Compound Excavatolide B Isolated from the Culture-Type Formosan Gorgonian Briareum excavatum YY Lin, SC Lin, CW Feng, PC Chen, YD Su, CM Li, SN Yang, YH Jean, PJ Sung, CY Duh, ZH Wen	Marine drugs	2015
Chemoprevention in gastrointestinal physiology and disease. Anti-inflammatory approaches for colorectal cancer chemoprevention AM Fajardo, GA Piazza	AJP Gastrointestinal and Liver Physiology	2015
Muscle Segment Homeobox Genes Direct Embryonic Diapause by Limiting Inflammation in the Uterus J Cha, KE Burnum-Johnson, A Bartos, Y Li, ES Baker, SC Tilton, BJ Webb-Robertson, PD Piehowski, ME Monroe, AG Jegga, S Murata, Y Hirota, SK Dey	The Journal of biological chemistry	2015
Endotoxin-Binding Peptides Derived from Casein Glycomacropeptide Inhibit Lipopolysaccharide-Stimulated Inflammatory Responses via Blockade of NF-κB activation in macrophages X Cheng, D Gao, B Chen, X Mao	Nutrients	2015
Pulmonary Venous Obstruction in Cancer Patients CC Liaw, H Chang, TS Yang, MS Wen	Journal of Oncology	2015
Silibinin down-regulates FAT10 and modulate TNF- /IFN- -induced chromosomal instability and apoptosis sensitivity Y Gao, SS Theng, WC Mah, CG Lee	Biology Open	2015
iTRAQ-based comparative proteomic analysis of Vero cells infected with virulent and CV777 vaccine strain-like strains of porcine epidemic diarrhea virus X Guo, H Hu, F Chen, Z Li, S Ye, S Cheng, M Zhang, Q He	Journal of Proteomics	2015
Mechanistic Perspectives of Maslinic Acid in Targeting Inflammation WH Yap, YM Lim	Biochemistry Research International	2015
Dietary Selenium Supplementation Modulates Growth of Brain Metastatic Tumors and Changes the Expression of Adhesion Molecules in Brain Microvessels JK Wrobel, G Wolff, R Xiao, RF Power, M Toborek	Biological Trace Element Research	2015
Turkish Scorzonera Species Extracts Attenuate Cytokine Secretion via Inhibition of NF-κB Activation, Showing Anti-Inflammatory Effect in Vitro ÖB Acikara, J Hošek, P Babula, J Cvačka, M Budešínský, M Dračinský, GS İşcan, D Kadlecová, L Ballová, K Šmejkal	Molecules (Basel, Switzerland)	2015
Epithelial derived CTGF promotes breast tumor progression via inducing EMT and collagen I fibers deposition X Zhu, J Zhong, Z Zhao, J Sheng, J Wang, J Liu, K Cui, J Chang, H Zhao, S Wong	Oncotarget	2015
The antidiabetic compound 2-dodecyl-6-methoxycyclohexa-2,5-diene-1,4-dione, isolated from averrhoa carambola L., demonstrates significant antitumor potential against human breast cancer cells Y Gao, R Huang, Y Gong, HS Park, Q Wen, NM Almosnid, UD Chippada-Venkata, NA Hosain, E Vick, A Farone, E Altman	Oncotarget	2015
Protective Effect of Super-Critical Carbon Dioxide Fluid Extract from Flowers and Buds of Chrysanthemum indicum Linnén Against Ultraviolet-Induced Photo-Aging in Mice X Zhang, YL Xie, XT Yu, ZQ Su, J Yuan, YC Li, ZR Su, JY Zhan, XP Lai	Rejuvenation Research	2015
Molecular docking simulation analysis of the interaction of dietary flavonols with heat shock protein 90 Singh SP, Deb CR, Ahmed SU, Saratchandra Y, Konwar BK	Journal of Biomedical Research	2015
A novel human truncated IL12rβ1-Fc fusion protein ameliorates experimental autoimmune encephalomyelitis via specific binding of p40 to inhibit Th1 and Th17 cell differentiation Guo W, Wang C, Wang X, Luo C, Yu D, Wang Y, Chen Y, Lei W, Gao X, Yao W	Oncotarget	2015
Functional characterization of a competitive peptide antagonist of p65 in human macrophage-like cells suggests therapeutic potential for chronic inflammation M Srinivasan, D Lahiri, C Blackburn	Drug design, development and therapy	2014
Immunomodulatory Effects of ZYM-201 on LPS-stimulated B Cells YE Lee, S Kim, WJ Jung, HS Lee, MY Kim	Immune Network	2014
Chronic inflammation in biomaterial-induced periprosthetic osteolysis: NF-κB as a therapeutic target T Lin, Y Tamaki, J Pajarinen, HA Waters, DK Woo, Z Yao, SB Goodman	Acta Biomaterialia	2014
How the Venom from the Ectoparasitoid Wasp Nasonia vitripennis Exhibits Anti-Inflammatory Properties on Mammalian Cell Lines EL Danneels, S Gerlo, K Heyninck, KV Craenenbroeck, KD Bosscher, G Haegeman, DC de Graaf	PloS one	2014
Toad Glandular Secretions and Skin Extractions as Anti-Inflammatory and Anticancer Agents J Qi, CK Tan, SM Hashimi, AH Zulfiker, D Good, MQ Wei	Evidence-Based Complementary and Alternative Medicine	2014
A molecular targeting against nuclear factor-κB, as a chemotherapeutic approach for human malignant mesothelioma S Nishikawa, A Tanaka, A Matsuda, K Oida, H Jang, K Jung, Y Amagai, G Ahn, N Okamoto, S Ishizaka, H Matsuda	Cancer Medicine	2014
MicroRNA-362 induces cell proliferation and apoptosis resistance in gastric cancer by activation of NF-κB signaling J Xia, L Chen, W Jian, KB Wang, Y Yang, W He, Y He, D Chen, W Li	Journal of Translational Medicine	2014
Green tea: a tea or a remedy? DK Song	Integrative Medicine Research	2014
Basal NF- B controls IL-7 responsiveness of quiescent naive T cells ML Miller, M Mashayekhi, L Chen, P Zhou, X Liu, M Michelotti, NT Gunn, S Powers, X Zhu, C Evaristo, ML Alegre, LL Molinero	Proceedings of the National Academy of Sciences	2014
Safety and feasibility of adjunctive dexamethasone infusion into the adventitia of the femoropopliteal artery following endovascular revascularization CD Owens, WJ Gasper, JP Walker, HF Alley, MS Conte, SM Grenon	Journal of Vascular Surgery	2014
Biological Pathways and Potential Targets for Prevention and Therapy of Chronic Allograft Nephropathy BM Shrestha, J Haylor	BioMed Research International	2014
The American cranberry: first insights into the whole genome of a species adapted to bog habitat J Polashock, E Zelzion, D Fajardo, J Zalapa, L Georgi, D Bhattacharya, N Vorsa	BMC plant biology	2014
MAG-EPA and 17,18-EpETE target cytoplasmic signalling pathways to reduce short-term airway hyperresponsiveness R Khaddaj-Mallat, É Rousseau	Pflügers Archiv - European Journal of Physiology	2014
The effect of serine protease inhibitors on airway inflammation in a chronic allergen-induced asthma mouse model CC Lin, LJ Lin, SD Wang, CJ Chiang, YP Chao, J Lin, ST Kao	Mediators of Inflammation	2014
Alpha-lipoic acid as a pleiotropic compound with potential therapeutic use in diabetes and other chronic diseases MB Gomes, CA Negrato	Diabetology & metabolic syndrome	2014
Strontium chloride: can it be a new treatment option for ulcerative colitis? F Topal, O Yonem, N Tuzcu, M Tuzcu, H Ataseven, M Akyol	BioMed Research International	2014
Lipopolysaccharide differentially affects the osteogenic differentiation of periodontal ligament stem cells and bone marrow mesenchymal stem cells through Toll-like receptor 4 mediated nuclear factor κB pathway C Li, B Li, Z Dong, L Gao, X He, L Liao, C Hu, Q Wang, Y Jin	Stem Cell Research & Therapy	2014
Silibinin and its 2,3-dehydro-derivative inhibit basal cell carcinoma growth via suppression of mitogenic signaling and transcription factors activation: SILIBININ AND ITS 2,3-DEHYDRO-DERIVATIVE INHIBIT BCC C Tilley, G Deep, C Agarwal, MF Wempe, D Biedermann, K Valentová, V Kren, R Agarwal	Molecular Carcinogenesis	2014
Therapeutic potency of saponin rich aqueous extract of Scoparia dulcis L. in alloxan induced diabetes in rats A Muthuraman, S Krishan, PS Perumal, PV Anaswara	AYU (An International Quarterly Journal of Research in Ayurveda)	2014
Antineoplastic Effect of Decoy Oligonucleotide Derived from MGMT Enhancer T Canello, H Ovadia, M Refael, D Zrihan, T Siegal, I Lavon, SG Lee	PloS one	2014
Effects of rhamnocitrin 4-β-D-galactopyranoside, isolated from Astragalus hamosus on toxicity models in vitro I Krasteva, M Mitcheva, M Kondeva-Burdina	Pharmacognosy magazine	2014
Flavonoid Fraction of Bergamot Juice Reduces LPS-Induced Inflammatory Response through SIRT1-Mediated NF-κB Inhibition in THP-1 Monocytes R Risitano, M Currò, S Cirmi, N Ferlazzo, P Campiglia, D Caccamo, R Ientile, M Navarra, GL Volti	PloS one	2014
Inflammation to cancer: The molecular biology in the pancreas (Review) S Ling, T Feng, K Jia, YU TIAN, Y Li	Oncology Letters	2014
Effects of aspirin on the expression of nuclear factor-κB in a rat model of acute pulmonary embolism Wang LC, Jiang RL, Zhang W, Wei LL, Yang RH	World Journal of Emergency Medicine	2014
Anti-Inflammatory Strategies in Cartilage Repair Zhang Y, Pizzute T, Pei M	Tissue engineering. Part B, Reviews	2014
Clinical significance and therapeutic value of glutathione peroxidase 3 (GPx3) in hepatocellular carcinoma Qi X, Ng KT, Lian QZ, Liu XB, Li CX, Geng W, Ling CC, Ma YY, Yeung WH, Tu WW, Fan ST, Lo CM, Man K	Oncotarget	2014
Protein F-induced immune tolerance in liver transplantation in rats. Zhuang J, Wang Y, Du Z, Wang S	Molecular Biology Reports	2014
Effect of histone deacetylase inhibitor JNJ-26481585 in pain. Capasso KE, Manners MT, Quershi RA, Tian Y, Gao R, Hu H, Barrett JE, Sacan A, Ajit SK	Journal of molecular neuroscience : MN	2014
Functional Imaging of Rel Expression in Inflammatory Processes Using Bioluminescence Imaging System in Transgenic Mice X Yang, H Jing, K Zhao, R Sun, Z Liu, Y Ying, L Ci, Y Kuang, F Huang, Z Wang, J Fei, MM Rodrigues	PloS one	2013
NF-κB inhibitor targeted to activated endothelium demonstrates a critical role of endothelial NF-κB in immune-mediated diseases B Sehnert, H Burkhardt, JT Wessels, A Schröder, MJ May, D Vestweber, J Zwerina, K Warnatz, F Nimmerjahn, G Schett, S Dübel, RE Voll	Proceedings of the National Academy of Sciences	2013
Shikonin Suppresses Human T Lymphocyte Activation through Inhibition of IKK β Activity and JNK Phosphorylation T Li, F Yan, R Wang, H Zhou, L Liu	Evidence-Based Complementary and Alternative Medicine	2013
Hirsutella sinensis mycelium suppresses interleukin-1β and interleukin-18 secretion by inhibiting both canonical and non-canonical inflammasomes TT Huang, KY Chong, DM Ojcius, YH Wu, YF Ko, CY Wu, J Martel, CC Lu, HC Lai, JD Young	Scientific Reports	2013
Signal Transduction and Molecular Targets of Selected Flavonoids AM Bode, Z Dong	Antioxidants & Redox Signaling	2013
Characterization of a novel curcumin analog P1 as potent inhibitor of the NF-κB signaling pathway with distinct mechanisms Y Peng, J Zheng, Y Zhou, J Li	Acta Pharmacologica Sinica	2013
The Class III Histone Deacetylase Sirtuin 1 in Immune Suppression and Its Therapeutic Potential in Rheumatoid Arthritis S Kong, P Yeung, D Fang	Journal of Genetics and Genomics	2013
Turning an antiviral into an anticancer drug: Nanoparticle delivery of acyclovir monophosphate J Yao, Y Zhang, S Ramishetti, Y Wang, L Huang	Journal of Controlled Release	2013
Galangin Abrogates Ovalbumin-Induced Airway Inflammation via Negative Regulation of NF-κB WJ Zha, Y Qian, Y Shen, Q Du, FF Chen, ZZ Wu, X Li, M Huang	Evidence-Based Complementary and Alternative Medicine	2013
The S100A4 Oncoprotein Promotes Prostate Tumorigenesis in a Transgenic Mouse Model: Regulating NFκB through the RAGE Receptor HR Siddique, VM Adhami, A Parray, JJ Johnson, IA Siddiqui, MT Shekhani, I Murtaza, N Ambartsumian, BR Konety, H Mukhtar, M Saleem	Genes & cancer	2013
Mitochondria and reactive oxygen species: physiology and pathophysiology S Bolisetty, EA Jaimes	International journal of molecular sciences	2013
Chemical characterization of Brickellia cavanillesii (Asteraceae) using gas chromatographic methods ER Eshiet, J Zhu, TA Anderson, EE Smith	Food Science & Nutrition	2013
Aspirin attenuates angiotensin II-induced inflammation in bone marrow mesenchymal stem cells via the inhibition of ERK1/2 and NF-κB activation F Zhang, M Lu, H Wang, T Ren	Biomedical Reports	2013
Anti-inflammatory effect of procyanidins from wild grape (Vitis amurensis) seeds in LPS-induced RAW 264.7 cells MJ Bak, VL Truong, HS Kang, M Jun, WS Jeong	Oxidative Medicine & Cellular Longevity	2013
Digitoflavone inhibits IκBα kinase and enhances apoptosis induced by TNFα through downregulation of expression of nuclear factor κB-regulated gene products in human pancreatic cancer cells X Cai, W Lu, Y Yang, J Yang, J Ye, Z Gu, C Hu, X Wang, P Cao	PloS one	2013
Erucin exerts anti-inflammatory properties in murine macrophages and mouse skin: possible mediation through the inhibition of NFκB signaling HJ Cho, KW Lee, JH Park	International journal of molecular sciences	2013
N-octanoyl dopamine inhibits the expression of a subset of κB regulated genes: potential role of p65 Ser276 phosphorylation MC Hottenrott, J Wedel, S Gaertner, E Stamellou, T Kraaij, L Mandel, R Loesel, C Sticht, S Hoeger, L Ait-Hsiko, A Schedel, M Hafner, B Yard, C Tsagogiorgas	PloS one	2013
Experimental and Clinical Pharmacology of Andrographis paniculata and Its Major Bioactive Phytoconstituent Andrographolide T Jayakumar, CY Hsieh, JJ Lee, JR Sheu	Evidence-Based Complementary and Alternative Medicine	2013
PMS1077 sensitizes TNF-α induced apoptosis in human prostate cancer cells by blocking NF-κB signaling pathway J Shi, J Chen, N Serradji, X Xu, H Zhou, Y Ma, Z Sun, P Jiang, Y Du, J Yang, C Dong, Q Wang	PloS one	2013
Saikosaponin-d Enhances the Anticancer Potency of TNF-α via Overcoming Its Undesirable Response of Activating NF-Kappa B Signalling in Cancer Cells VK Wong, MM Zhang, H Zhou, KY Lam, PL Chan, CK Law, PY Yue, L Liu	Evidence-Based Complementary and Alternative Medicine	2013
Crystal structure of a human IκB kinase β asymmetric dimer S Liu, YR Misquitta, A Olland, MA Johnson, KS Kelleher, R Kriz, LL Lin, M Stahl, L Mosyak	The Journal of biological chemistry	2013
Antioxidant Function of Isoflavone and 3,3′-Diindolylmethane: Are They Important for Cancer Prevention and Therapy? Y Li, D Kong, A Ahmad, B Bao, FH Sarkar	Antioxidants & Redox Signaling	2013
Aiming for a Better Understanding and Management of Cancer-Related Fatigue EC Neefjes, MJ van der Vorst, S Blauwhoff-Buskermolen, HM Verheul	The oncologist	2013
Soy Saponins Meditate the Progression of Colon Cancer in Rats by Inhibiting the Activity of β -Glucuronidase and the Number of Aberrant Crypt Foci but Not Cyclooxygenase-2 Activity YW Guo, YH Chen, WC Chiu, H Liao, SH Lin	ISRN Oncology	2013
Protein tyrosine phosphatase controls breast cancer invasion through the expression of matrix metalloproteinase-9 Hwang BM, Chae HS, Jeong YJ, Lee YR, Noh EM, Youn HZ, Jung SH, Yu HN, Chung EY, Kim JS	BMB Reports	2013
Sulforaphane controls TPA-induced MMP-9 expression through the NF-κB signaling pathway, but not AP-1, in MCF-7 breast cancer cells Lee YR, Noh EM, Han JH, Kim JM, Hwang BM, Kim BS, Lee SH, Jung SH, Youn HJ, Chung EY, Kim JS	BMB Reports	2013
Anticancer potential of rhamnocitrin 4'-β-D-galactopyranoside against N-diethylnitrosamine-induced hepatocellular carcinoma in rats. Saleem S, Shaharyar MA, Khusroo MJ, Ahmad P, Rahman RU, Ahmad K, Alam MJ, Al-Harbi NO, Iqbal M, Imam F	Molecular and Cellular Biochemistry	2013
The Anti-Inflammatory Role of Vitamin E in Prevention of Osteoporosis AS Nazrun, M Norazlina, M Norliza, SI Nirwana	Advances in pharmacological sciences	2012
Tumor necrosis factor-like weak inducer of apoptosis and its potential roles in lupus nephritis ZC Liu, QL Zhou	Inflammation Research	2012
Gambogic acid inhibits TNF-α-induced invasion of human prostate cancer PC3 cells in vitro through PI3K/Akt and NF-κB signaling pathways L Lü, D Tang, L Wang, L Huang, G Jiang, X Xiao, F Zeng	Acta Pharmacologica Sinica	2012
A facile inhibitor screening of SARS coronavirus N protein using nanoparticle-based RNA oligonucleotide C Roh	International Journal of Nanomedicine	2012
Novel Marine Phenazines as Potential Cancer Chemopreventive and Anti-Inflammatory Agents TP Kondratyuk, EJ Park, R Yu, RB van Breemen, RN Asolkar, BT Murphy, W Fenical, JM Pezzuto	Marine drugs	2012
The biological activity of auranofin: implications for novel treatment of diseases JM Madeira, DL Gibson, WF Kean, A Klegeris	Inflammopharmacology	2012
Differential regulation of nuclear factor-kappa B subunits on epidermal keratinocytes by ultraviolet B and tacrolimus CS Wu, CC Lan, HY Kuo, CY Chai, WT Chen, GS Chen	The Kaohsiung Journal of Medical Sciences	2012
Side Population Cells from Human Melanoma Tumors Reveal Diverse Mechanisms for Chemoresistance Y Luo, LZ Ellis, K Dallaglio, M Takeda, WA Robinson, SE Robinson, W Liu, KD Lewis, MD McCarter, R Gonzalez, DA Norris, DR Roop, RA Spritz, NG Ahn, M Fujita	Journal of Investigative Dermatology	2012
AlzPathway: a comprehensive map of signaling pathways of Alzheimer’s disease S Mizuno, R Iijima, S Ogishima, M Kikuchi, Y Matsuoka, S Ghosh, T Miyamoto, A Miyashita, R Kuwano, H Tanaka	BMC Systems Biology	2012
Flaking process increases the NF-κB inhibition activity and melanoidin extractability of coffee YF Chu, K Hu, T Hatzold, RM Black, D Chen	Food Science & Nutrition	2012
Health-Promoting Properties of Lactobacillus helveticus V Taverniti, S Guglielmetti	Frontiers in microbiology	2012
Dynamical modeling of drug effect using hybrid systems X Li, L Qian, ER Dougherty	EURASIP Journal on Bioinformatics and Systems Biology	2012
Keampferol-3-O-rhamnoside abrogates amyloid beta toxicity by modulating monomers and remodeling oligomers and fibrils to non-toxic aggregates MG Sharoar, A Thapa, M Shahnawaz, VS Ramasamy, ER Woo, SY Shin, IS Park	Journal of Biomedical Science	2012
S-layer protein mediates the stimulatory effect of Lactobacillus helveticus MIMLh5 on innate immunity V Taverniti, M Stuknyte, M Minuzzo, S Arioli, ID Noni, C Scabiosi, ZM Cordova, I Junttila, S Hämäläinen, H Turpeinen, D Mora, M Karp, M Pesu, S Guglielmetti	Applied and environmental microbiology	2012
Primary, Secondary Metabolites, Photosynthetic Capacity and Antioxidant Activity of the Malaysian Herb Kacip Fatimah (Labisia Pumila Benth) Exposed to Potassium Fertilization under Greenhouse Conditions MH Ibrahim, HZ Jaafar, E Karimi, A Ghasemzadeh	International journal of molecular sciences	2012
Neoflavonoids and tetrahydroquinolones as possible cancer chemopreventive agents S Luqman, A Meena, P Singh, TP Kondratyuk, LE Marler, JM Pezzuto, AS Negi	Chemical Biology & Drug Design	2012
Protective role of estrogen-induced miRNA-29 expression in carbon tetrachloride-induced mouse liver injury Y Zhang, L Wu, Y Wang, M Zhang, L Li, D Zhu, X Li, H Gu, CY Zhang, K Zen	The Journal of biological chemistry	2012
Aspirin‐/ TMZ ‐coloaded Microspheres Exert Synergistic Antiglioma Efficacy via Inhibition of β‐catenin Transactivation ZD Shi, XM Qian, CY Liu, L Han, KL Zhang, LY Chen, JX Zhang, PY Pu, XB Yuan, CS Kang	CNS Neuroscience & Therapeutics	2012
Molecular Pathways: Pathogenesis and Clinical Implications of Microbiome Alteration in Esophagitis and Barrett Esophagus: Figure 1 L Yang, F Francois, Z Pei	Clinical cancer research	2012
Anti-Inflammatory Potential of Ethanolic Leaf Extract of Eupatorium adenophorum Spreng. Through Alteration in Production of TNF-α, ROS and Expression of Certain Genes AK Chakravarty, T Mazumder, SN Chatterjee	Evidence-based complementary and alternative medicine : eCAM	2011
Arvelexin from Brassica rapa suppresses NF-κB-regulated pro-inflammatory gene expression by inhibiting activation of IκB kinase JS Shin, YS Noh, YS Lee, YW Cho, NI Baek, MS Choi, TS Jeong, E Kang, HG Chung, KT Lee	British Journal of Pharmacology	2011
A Cell-penetrating Peptide Suppresses Inflammation by Inhibiting NF-κB Signaling YF Wang, X Xu, X Fan, C Zhang, Q Wei, X Wang, W Guo, W Xing, J Yu, JL Yan, HP Liang	Molecular Therapy	2011
Bortezomib Induces Nuclear Translocation of IκBα Resulting in Gene-Specific Suppression of NF-κB–Dependent Transcription and Induction of Apoptosis in CTCL A Juvekar, S Manna, S Ramaswami, TP Chang, HY Vu, CC Ghosh, MY Celiker, I Vancurova	Molecular cancer research : MCR	2011
Inhibition of nuclear factor kappa-B signaling reduces growth in medulloblastoma in vivo SE Spiller, NJ Logsdon, LA Deckard, H Sontheimer	BMC Cancer	2011
Prevention of the β-amyloid peptide-induced inflammatory process by inhibition of double-stranded RNA-dependent protein kinase in primary murine mixed co-cultures J Couturier, M Paccalin, M Morel, F Terro, S Milin, R Pontcharraud, B Fauconneau, G Page	Journal of Neuroinflammation	2011
Catechin suppresses an array of signalling molecules and modulates alcohol-induced endotoxin mediated liver injury in a rat model S Bharrhan, A Koul, K Chopra, P Rishi	PloS one	2011
Nuclear Factor-κB: a Key Regulator in Health and Disease of Lungs S Batra, G Balamayooran, MK Sahoo	Archivum Immunologiae et Therapiae Experimentalis	2011
Modulation of Pancreatic Cancer Chemoresistance by Inhibition of TAK1 D Melisi, Q Xia, G Paradiso, J Ling, T Moccia, C Carbone, A Budillon, JL Abbruzzese, PJ Chiao	JNCI Journal of the National Cancer Institute	2011
The role of innate immune-stimulated epithelial apoptosis during gastrointestinal inflammatory diseases RH Siggers, DJ Hackam	Cellular and Molecular Life Sciences	2011
Short term supplementation of dietary antioxidants selectively regulates the inflammatory responses during early cutaneous wound healing in diabetic mice NY Park, Y Lim	Nutrition & Metabolism	2011
Nuclear Factor-κB (NF-κB) Mediates a Protective Response in Cancer Cells Treated with Inhibitors of Fatty Acid Synthase* CR Lemmon, JH Woo, E Tully, K Wilsbach, E Gabrielson	The Journal of biological chemistry	2011
Effects of Nitrogen Fertilization on Synthesis of Primary and Secondary Metabolites in Three Varieties of Kacip Fatimah (Labisia Pumila Blume) MH Ibrahim, HZ Jaafar, A Rahmat, ZA Rahman	International journal of molecular sciences	2011
Zyflamend suppresses growth and sensitizes human pancreatic tumors to gemcitabine in an orthotopic mouse model through modulation of multiple targets AB Kunnumakkara, B Sung, J Ravindran, P Diagaradjane, A Deorukhkar, S Dey, C Koca, Z Tong, JG Gelovani, S Guha, S Krishnan, BB Aggarwal	International Journal of Cancer	2011
Suppression of tumor necrosis factor-α-induced nuclear factor κB activation and aromatase activity by capsaicin and its analog capsazepine S Luqman, A Meena, LE Marler, TP Kondratyuk, JM Pezzuto	Journal of Medicinal Food	2011
Chemistry and biology of rocaglamides (= flavaglines) and related derivatives from aglaia species (meliaceae) SS Ebada, N Lajkiewicz, JA Porco, M Li-Weber, P Proksch		2011
Selective Abrogation of BiP/GRP78 Blunts Activation of NF- B through the ATF6 Branch of the UPR: Involvement of C/EBP and mTOR-Dependent Dephosphorylation of Akt S Nakajima, N Hiramatsu, K Hayakawa, Y Saito, H Kato, T Huang, J Yao, AW Paton, JC Paton, M Kitamura	Molecular and cellular biology	2011
Two MicroRNAs Encoded within the Bovine Herpesvirus 1 Latency-Related Gene Promote Cell Survival by Interacting with RIG-I and Stimulating NF- B-Dependent Transcription and Beta Interferon Signaling Pathways LF da Silva, C Jones	Journal of virology	2011
A failure of TNFAIP3 negative regulation maintains sustained NF-κB activation in Sjögren’s syndrome M Sisto, S Lisi, DD Lofrumento, G Ingravallo, E Maiorano, M DAmore	Histochemistry and Cell Biology	2011
Inducible nitric oxide synthase (iNOS) in muscle wasting syndrome, sarcopenia, and cachexia. Hall DT, Ma JF, Marco SD, Gallouzi IE	Aging	2011
Sanggenon C decreases tumor cell viability associated with proteasome inhibition Huang H, Liu N, Zhao K, Zhu C, Lu X, Li S, Lian W, Zhou P, Dong X, Zhao C, Guo H, Zhang C, Yang C, Wen G, Lu L, Li X, Guan L, Liu C, Wang X, Dou QP, Liu J	Frontiers in bioscience (Elite edition)	2011
Nuclear factor-kappaB inducing kinase is required for graft-versus-host disease C Sánchez-Valdepeñas, L Casanova, I Colmenero, M Arriero, A González, N Lozano, M González-Vicent, MA Díaz, L Madero, M Fresno, M Ramírez	Haematologica	2010
Regulation of IkappaBalpha function and NF-kappaB signaling: AEBP1 is a novel proinflammatory mediator in macrophages A Majdalawieh, HS Ro	Mediators of Inflammation	2010
Tyrosine phosphorylation is required for IkappaB kinase-beta (IKKbeta) activation and function in osteoclastogenesis I Darwech, JE Otero, MA Alhawagri, Y Abu-Amer	The Journal of biological chemistry	2010
Beyond reverse pharmacology: Mechanism-based screening of Ayurvedic drugs RD Lele	Journal of Ayurveda and integrative medicine	2010
Computational modeling with forward and reverse engineering links signaling network and genomic regulatory responses: NF-κB signaling-induced gene expression responses in inflammation SC Peng, DS Wong, KC Tung, YY Chen, CC Chao, CH Peng, YJ Chuang, CY Tang	BMC bioinformatics	2010
Detrimental effect of the proteasome inhibitor, bortezomib in bacterial superantigen- and lipopolysaccharide-induced systemic inflammation AY Tilahun, JE Theuer, R Patel, CS David, G Rajagopalan	Molecular Therapy	2010
Curcumin improves prostanoid ratio in diabetic mesenteric arteries associated with cyclooxygenase-2 and NF-κB suppression S Rungseesantivanon, N Thengchaisri, P Ruangvejvorachai, S Patumraj	Diabetes, metabolic syndrome and obesity : targets and therapy	2010
Natural anti-inflammatory agents for pain relief JC Maroon, JW Bost, A Maroon	Surgical neurology international	2010
Flowers of Inula japonica Attenuate Inflammatory Responses JH Choi, YN Park, Y Li, MH Jin, J Lee, Y Lee, JK Son, HW Chang, E Lee	Immune Network	2010
Inhibition of choriodecidual cytokine production and inflammatory gene expression by selective I-kappaB kinase (IKK) inhibitors DD Silva, MD Mitchell, JA Keelan	British Journal of Pharmacology	2010
Dietary bioflavonoids inhibit Escherichia coli ATP synthase in a differential manner N Chinnam, PK Dadi, SA Sabri, M Ahmad, MA Kabir, Z Ahmad	International Journal of Biological Macromolecules	2010
Maternal Obesity Induces Sustained Inflammation in Both Fetal and Offspring Large Intestine of Sheep X Yan, Y Huang, H Wang, M Du, BW Hess, SP Ford, PW Nathanielsz, MJ Zhu	Inflammatory Bowel Diseases	2010
γ-Tocotrienol Inhibits Pancreatic Tumors and Sensitizes Them to Gemcitabine Treatment by Modulating the Inflammatory Microenvironment AB Kunnumakkara, B Sung, J Ravindran, P Diagaradjane, A Deorukhkar, S Dey, C Koca, VR Yadav, Z Tong, JG Gelovani, S Guha, S Krishnan, BB Aggarwal	Cancer research	2010
In vitro and In vivo Studies on Stilbene Analogs as Potential Treatment Agents for Colon Cancer S Paul, CS Mizuno, HJ Lee, X Zheng, S Chajkowisk, JM Rimoldi, A Conney, N Suh, AM Rimando	European Journal of Medicinal Chemistry	2010
Transcriptional control of maladaptive and protective responses in alcoholics: a role of the NF-κB system T Yakovleva, I Bazov, H Watanabe, KF Hauser, G Bakalkin	Brain, Behavior, and Immunity	2010
Enzymatic Extract from Ecklonia cava Induces the Activation of Lymphocytes by IL-2 Production Through the Classical NF-κB Pathway G Ahn, E Park, WW Lee, JW Hyun, KW Lee, T Shin, YJ Jeon, Y Jee	Marine Biotechnology	2010
Up-Regulation of Toll-Like Receptor 4/Nuclear Factor-κB Signaling Is Associated with Enhanced Adipogenesis and Insulin Resistance in Fetal Skeletal Muscle of Obese Sheep at Late Gestation X Yan, MJ Zhu, W Xu, JF Tong, SP Ford, PW Nathanielsz, M Du	Endocrinology	2010
A Dairy Bacterium Displays InVitro Probiotic Properties for the Pharyngeal Mucosa by Antagonizing Group A Streptococci and Modulating the Immune Response S Guglielmetti, V Taverniti, M Minuzzo, S Arioli, I Zanoni, M Stuknyte, F Granucci, M Karp, D Mora	Infection and immunity	2010
Flavonoids activate pregnane × receptor-mediated CYP3A4 gene expression by inhibiting cyclin-dependent kinases in HepG2 liver carcinoma cells H Dong, W Lin, J Wu, T Chen	BMC Biochemistry	2010
Pulmonary surfactant: an immunological perspective ZC Chroneos, Z Sever-Chroneos, VL Shepherd	Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology	2009
Gene therapy targeting nuclear factor-kappaB: towards clinical application in inflammatory diseases and cancer SW Tas, MJ Vervoordeldonk, PP Tak	Current gene therapy	2009
Secretion and uptake of TAT-fusion proteins produced by engineered mammalian cells A Koutsokeras, PS Kabouridis	Biochimica et Biophysica Acta	2009
NF-κB regulation: the nuclear response AK Mankan, MW Lawless, SG Gray, D Kelleher, R McManus	Journal of Cellular and Molecular Medicine	2009
A new synthetic protein, TAT-RH, inhibits tumor growth through the regulation of NFκB activity D Sorriento, A Campanile, G Santulli, E Leggiero, L Pastore, B Trimarco, G Iaccarino	Molecular Cancer	2009
Maternal obesity, inflammation, and fetal skeletal muscle development M Du, X Yan, JF Tong, J Zhao, MJ Zhu	Biology of reproduction	2009
Curcumin decreased oxidative stress, inhibited NF-kappaB activation, and improved liver pathology in ethanol-induced liver injury in rats S Samuhasaneeto, D Thong-Ngam, O Kulaputana, D Suyasunanont, N Klaikeaw	Journal of biomedicine & biotechnology	2009
Anti-inflammatory and arthritic effects of thiacremonone, a novel sulfur compound isolated from garlic via inhibition of NF-kappaB JO Ban, JH Oh, TM Kim, DJ Kim, HS Jeong, SB Han, JT Hong	Arthritis Research & Therapy	2009
Pathogen recognition and inflammatory signaling in innate immune defenses TH Mogensen	Clinical microbiology reviews	2009
Early gene expression changes induced by the bacterial superantigen staphylococcal enterotoxin B and its modulation by a proteasome inhibitor G Rajagopalan, AY Tilahun, YW Asmann, CS David	Physiological genomics	2009
Echinacea increases arginase activity and has anti-inflammatory properties in RAW 264.7 macrophage cells, indicative of alternative macrophage activation Z Zhai, A Solco, L Wu, ES Wurtele, ML Kohut, PA Murphy, JE Cunnick	Journal of Ethnopharmacology	2009
Delphinidin, an anthocyanidin in pigmented fruits and vegetables, induces apoptosis and cell cycle arrest in human colon cancer HCT116 cells JM Yun, F Afaq, N Khan, H Mukhtar	Molecular Carcinogenesis	2009
A Phase I Trial of Bortezomib with Temozolomide in Patients with Advanced Melanoma: Toxicities, Antitumor Effects, and Modulation of Therapeutic Targets Y Su, KI Amiri, LW Horton, Y Yu, GD Ayers, E Koehler, MC Kelley, I Puzanov, A Richmond, JA Sosman	Clinical cancer research	2009
The silent estrogen receptor--can we make it speak? M Billam, AE Witt, NE Davidson	Cancer biology & therapy	2009
Oral administration of blueberry inhibits angiogenic tumor growth and enhances survival of mice with endothelial cell neoplasm G Gordillo, H Fang, S Khanna, J Harper, G Phillips, CK Sen	Antioxidants & Redox Signaling	2009
Growth inhibitory effects of dihydroartemisinin on pancreatic cancer cells: involvement of cell cycle arrest and inactivation of nuclear factor-κB H Chen, B Sun, S Wang, S Pan, Y Gao, X Bai, D Xue	Journal of Cancer Research and Clinical Oncology	2009
The ubiquitin-proteasome system: A novel target for anticancer and anti-inflammatory drug research H Ostrowska	Cellular & Molecular Biology Letters	2008
Celecoxib inhibits growth of tumors in a syngeneic rat liver metastases model for colorectal cancer P Heer, MH Sandel, G Guertens, G Boeck, MM Koudijs, JF Nagelkerke, JM Junggeburt, EA de Bruijn, CJ van de Velde, PJ Kuppen	Cancer Chemotherapy and Pharmacology	2008
ATL-1, an analogue of aspirin-triggered lipoxin A4, is a potent inhibitor of several steps in angiogenesis induced by vascular endothelial growth factor PF Cezar-de-Mello, AM Vieira, V Nascimento-Silva, CG Villela, C Barja-Fidalgo, IM Fierro	British Journal of Pharmacology	2008
Nanoparticles containing anti-inflammatory agents as chemotherapy adjuvants: optimization and in vitro characterization X Lu, MD Howard, M Mazik, J Eldridge, JJ Rinehart, M Jay, M Leggas	The AAPS Journal	2008
DNA mimicry by a high-affinity anti-NF-kappaB RNA aptamer NJ Reiter, LJ 3rd, SE Butcher	Nucleic Acids Research	2008
Differential effects of black raspberry and strawberry extracts on BaPDE-induced activation of transcription factors and their target genes J Li, D Zhang, GD Stoner, C Huang	Molecular Carcinogenesis	2008
NF-KappaB expression correlates with apoptosis and angiogenesis in clear cell renal cell carcinoma tissues I Meteoglu, IH Erdogdu, N Meydan, M Erkus, S Barutca	Journal of Experimental & Clinical Cancer Research	2008
Curcumin Decreases Specificity Protein Expression in Bladder Cancer Cells G Chadalapaka, I Jutooru, S Chintharlapalli, S Papineni, R Smith, X Li, S Safe	Cancer research	2008
Anti-inflammatory effects of ethanol extract from Kummerowia striata (Thunb.) Schindl on lps-stimulated RAW 264.7 cell. Tao JY, Zhao L, Huang ZJ, Zhang XY, Zhang SL, Zhang QG, Fei-Xiao, Zhang BH, Feng QL, Zheng GH	Inflammation	2008
Antipsoriatic effects of avarol-3'-thiosalicylate are mediated by inhibition of TNF-alpha generation and NF-kappaB activation in mouse skin M Amigó, M Payá, SD Rosa, MC Terencio	British Journal of Pharmacology	2007
Adipocyte Enhancer-binding Protein-1 Promotes Macrophage Inflammatory Responsiveness by Up-Regulating NF-κB via IκBα Negative Regulation A Majdalawieh, L Zhang, HS Ro, W Tansey	Molecular biology of the cell	2007
Differential activation of NF-kappaB and gene expression in oral epithelial cells by periodontal pathogens MR Milward, IL Chapple, HJ Wright, JL Millard, JB Matthews, PR Cooper	Clinical & Experimental Immunology	2007
Use of bioluminescent imaging to investigate the role of nuclear factor-κΒ in experimental non-small cell lung cancer metastasis GT Stathopoulos, TP Sherrill, W Han, RT Sadikot, VV Polosukhin, B Fingleton, FE Yull, TS Blackwell	Clinical & Experimental Metastasis	2007
Comparing HMG‐CoA reductase inhibitors Jones PH	Clinical Cardiology	2007
Interferon‐γ sensitizes hepatitis B virus‐expressing hepatocarcinoma cells to 5‐fluorouracil through inhibition of hepatitis B virus‐mediated nuclear factor‐κB activation Chung C, Park SG, Park YM, Joh J, Jung G	Cancer Science	2007
Local treatment with the selective IkappaB kinase beta inhibitor NEMO-binding domain peptide ameliorates synovial inflammation SW Tas, MJ Vervoordeldonk, N Hajji, MJ May, S Ghosh, PP Tak	Arthritis Research & Therapy	2006
Use of cell permeable NBD peptides for suppression of inflammation I Strickland, S Ghosh	Annals of the rheumatic diseases	2006
Inflammation and the metabolic syndrome: Role of angiotensin II and oxidative stress L Ferder, F Inserra, M Martínez-Maldonado	Current Hypertension Reports	2006
Arsenic trioxide, a potent inhibitor of NF-κB, abrogates allergen-induced airway hyperresponsiveness and inflammation LF Zhou, Y Zhu, XF Cui, WP Xie, AH Hu, KS Yin	Respiratory Research	2006
Effects of morphine, fentanyl and tramadol on human immune response. Liu Z, Gao F, Tian Y		2006
Expression of Smad7 in mouse eyes accelerates healing of corneal tissue after exposure to alkali S Saika, K Ikeda, O Yamanaka, T Miyamoto, Y Ohnishi, M Sato, Y Muragaki, A Ooshima, Y Nakajima, WW Kao, KC Flanders, AB Roberts	The American Journal of Pathology	2005
Mechanism of von Hippel-Lindau protein-mediated suppression of nuclear factor kappa B activity J An, MB Rettig	Molecular and cellular biology	2005
Role of nuclear factor-kappa B in melanoma KI Amiri, A Richmond	Cancer metastasis reviews	2005
Caffeic acid phenethyl ester modulates Helicobacter pylori-induced nuclear factor-kappa B and activator protein-1 expression in gastric epithelial cells MM Abdel-Latif, HJ Windle, BS el Homasany, K Sabra, D Kelleher	British Journal of Pharmacology	2005
Differences in patterns of infection and inflammation for corticosteroid treatment and chemotherapy in experimental invasive pulmonary aspergillosis V Balloy, M Huerre, JP Latgé, M Chignard	Infection and immunity	2005
Leukemia virus long terminal repeat activates NFkappaB pathway by a TLR3-dependent mechanism AL Abujamra, RA Spanjaard, I Akinsheye, X Zhao, DV Faller, SK Ghosh	Virology	2005
Inhibition of Cellular Proliferation and Induction of Apoptosis by Curcumin in Human Malignant Astrocytoma Cell Lines S Nagai, M Kurimoto, K Washiyama, Y Hirashima, T Kumanishi, S Endo	Journal of Neuro-Oncology	2005
Inflammation and conjugated linoleic acid: mechanisms of action and implications for human health MA Zulet, A Marti, MD Parra, JA Martínez	Journal of Physiology and Biochemistry	2005
Regulation of IκBα expression involves both NF-κB and the MAP kinase signaling pathways N Zhang, MH Ahsan, L Zhu, LC Sambucetti, AF Purchio, DB West	Journal of Inflammation	2005
Nuclear Factor-κB1 (p50) Limits the Inflammatory and Fibrogenic Responses to Chronic Injury Oakley F, Mann J, Nailard S, Smart DE, Mungalsingh N, Constandinou C, Ali S, Wilson SJ, Millward-Sadler H, Iredale JP, Mann DA	The American Journal of Pathology	2005
Therapeutic Effect of Topical Administration of SN50, an Inhibitor of Nuclear Factor-κB, in Treatment of Corneal Alkali Burns in Mice Saika S, Miyamoto T, Yamanaka O, Kato T, Ohnishi Y, Flanders KC, Ikeda K, Nakajima Y, Kao WW, Sato M, Muragaki Y, Ooshima A	The American Journal of Pathology	2005
Anti-inflammatory mechanism of oxymatrine in dextran sulfate sodium-induced colitis of rats Zheng P, Niu FL, Liu WZ, Shi Y, Lu LG	World journal of gastroenterology : WJG	2005
IKK2 Inhibitor Alleviates Kidney and Wasting Diseases in a Murine Model of Human AIDS A Heckmann, C Waltzinger, P Jolicoeur, M Dreano, MH Kosco-Vilbois, Y Sagot	The American Journal of Pathology	2004
Nuclear factor (NF)-kappaB proteins: therapeutic targets IM Verma	Annals of the rheumatic diseases	2004
Nuclear factor-?B: its role in health and disease A Kumar, Y Takada, AM Boriek, BB Aggarwal	Journal of Molecular Medicine	2004
Oxidative stress induces insulin resistance by activating the nuclear factor-kappa B pathway and disrupting normal subcellular distribution of phosphatidylinositol 3-kinase T Ogihara, T Asano, H Katagiri, H Sakoda, M Anai, N Shojima, H Ono, M Fujishiro, A Kushiyama, Y Fukushima, M Kikuchi, N Noguchi, H Aburatani, Y Gotoh, I Komuro, T Fujita	Diabetologia	2004
Development of sulfasalazine resistance in human T cells induces expression of the multidrug resistance transporter ABCG2 (BCRP) and augmented production of TNFalpha J der Heijden, MC de Jong, BA Dijkmans, WF Lems, R Oerlemans, I Kathmann, CG Schalkwijk, GL Scheffer, RJ Scheper, G Jansen	Annals of the rheumatic diseases	2004
Acquired resistance of human T cells to sulfasalazine: stability of the resistant phenotype and sensitivity to non-related DMARDs J der Heijden, MC de Jong, BA Dijkmans, WF Lems, R Oerlemans, I Kathmann, GL Scheffer, RJ Scheper, YG Assaraf, G Jansen	Annals of the rheumatic diseases	2004
Reduced infiltration and increased apoptosis of leukocytes at sites of inflammation by systemic administration of a membrane-permeable IkappaBalpha repressor NM Blackwell, P Sembi, JS Newson, T Lawrence, DW Gilroy, PS Kabouridis	Arthritis & Rheumatism	2004
Inflammatory Mechanisms Contributing to Pancreatic Cancer Development: B Farrow, Y Sugiyama, A Chen, E Uffort, W Nealon, BM Evers	Annals of Surgery	2004
Human Cytomegalovirus Stimulates Cellular IKK2 Activity and Requires the Enzyme for Productive Replication P Caposio, M Dreano, G Garotta, G Gribaudo, S Landolfo	Journal of virology	2004
Concentration-dependent effects of native and polymerised alpha1-antitrypsin on primary human monocytes, in vitro R Aldonyte, L Jansson, S Janciauskiene	BMC cell biology	2004
Molecular mechanisms of interleukin-10-mediated inhibition of NF-kappaB activity: a role for p50 F Driessler, K Venstrom, R Sabat, K Asadullah, AJ Schottelius	Clinical & Experimental Immunology	2004
Proteasome inhibitors up-regulate haem oxygenase-1 gene expression: requirement of p38 MAPK (mitogen-activated protein kinase) activation but not of NF-kappaB (nuclear factor kappaB) inhibition WT Wu, KH Chi, FM Ho, WC Tsao, WW Lin	Biochemical Journal	2004
Identification of a negative regulatory cis-element in the enhancer core region of the prostate-specific antigen promoter: implications for intersection of androgen receptor and nuclear factor-kappaB signalling in prostate cancer cells B Cinar, F Yeung, H Konaka, MW Mayo, MR Freeman, HE Zhau, LW Chung	Biochemical Journal	2004
Effect of all-trans retinoic acid on airway inflammation in asthmatic rats and its mechanism F Hong, J Hongfang, W Hongwei	Journal of Huazhong University of Science and Technology [Medical Sciences]	2004
Reduced levels of the adenomatous polyposis coli (APC) protein are associated with ceramide-induced apoptosis of colon cancer cells AS Jaiswal, S Narayan	Journal of Cancer Research and Clinical Oncology	2004
NF-??B Activation in Esophageal Adenocarcinoma: Relationship to Barrett??s Metaplasia, Survival, and Response to Neoadjuvant Chemoradiotherapy MM Abdel-Latif, J ORiordan, HJ Windle, E Carton, N Ravi, D Kelleher, JV Reynolds	Annals of Surgery	2004
An in vitro screening assay for inhibitors of proinflammatory mediators in herbal extracts using human synoviocyte cultures. Frondoza CG, Sohrabi A, Polotsky A, Phan PV, Hungerford DS, Lindmark L	In vitro cellular & developmental biology. Animal	2004
Modulatory properties of various natural chemopreventive agents on the activation of NF-kappaB signaling pathway. Jeong WS, Kim IW, Hu R, Kong AN	Pharmaceutical Research	2004
Inhibition of nuclear factor-kappa B prevents staphylococcal enterotoxin A-induced fever. Shao DZ, Lee JJ, Huang WT, Liao JF, Lin MT	Molecular and Cellular Biochemistry	2004
Synoviolin/Hrd1, an E3 ubiquitin ligase, as a novel pathogenic factor for arthropathy T Amano, S Yamasaki, N Yagishita, K Tsuchimochi, H Shin, K Kawahara, S Aratani, H Fujita, L Zhang, R Ikeda, R Fujii, N Miura, S Komiya, K Nishioka, I Maruyama, A Fukamizu, T Nakajima	Genes & development	2003
Constitutive nuclear factor-kappa B mRNA, protein overexpression and enhanced DNA-binding activity in thymidylate synthase inhibitor-resistant tumour cells W Wang, J Cassidy	British Journal of Cancer	2003
p53 activates ICAM-1 (CD54) expression in an NF-kappaB-independent manner VG Gorgoulis, P Zacharatos, A Kotsinas, D Kletsas, G Mariatos, V Zoumpourlis, KM Ryan, C Kittas, AG Papavassiliou	The EMBO Journal	2003
Dexamethasone prevents granulocyte-macrophage colony-stimulating factor-induced nuclear factor-kappaB activation, inducible nitric oxide synthase expression and nitric oxide production in a skin dendritic cell line AL Vital, M Gonçalo, MT Cruz, A Figueiredo, CB Duarte, MC Lopes	Mediators of Inflammation	2003
Dexamethasone prevents interleukin-1beta-induced nuclear factor-kappaB activation by upregulating IkappaB-alpha synthesis, in lymphoblastic cells M Castro-Caldas, AF Mendes, AP Carvalho, CB Duarte, MC Lopes	Mediators of Inflammation	2003
Cacospongionolide B suppresses the expression of inflammatory enzymes and tumour necrosis factor-alpha by inhibiting nuclear factor-kappa B activation I Posadas, SD Rosa, MC Terencio, M Payá, MJ Alcaraz	British Journal of Pharmacology	2003
NF-kappaB activation in peripheral blood mononuclear cells in neonatal asphyxia K Hasegawa, T Ichiyama, H Isumi, M Nakata, M Sase, S Furukawa	Clinical & Experimental Immunology	2003
IKKα Regulates Mitogenic Signaling through Transcriptional Induction of Cyclin D1 via Tcf C Albanese, K Wu, M D'Amico, C Jarrett, D Joyce, J Hughes, J Hulit, T Sakamaki, M Fu, A Ben-Ze'ev, JF Bromberg, C Lamberti, U Verma, RB Gaynor, SW Byers, RG Pestell, PA Silver	Molecular biology of the cell	2003
Ameliorative effects of sodium ferulate on experimental colitis and their mechanisms in rats Dong WG, Liu SP, Yu BP, Wu DF, Luo HS, Yu JP	World Journal of Gastroenterology	2003
Therapeutic administration of 3,4,5-trimethoxy-4'-fluorochalcone, a selective inhibitor of iNOS expression, attenuates the development of adjuvant-induced arthritis in rats. Rojas J, Payá M, Devesa I, Dominguez JN, Ferrándiz ML	Naunyn-Schmiedeberg's Archives of Pharmacology	2003
Differential role of platelet-activating factor in gastric mucosal ulcer healing. Slomiany BL, Slomiany A	InflammoPharmacology	2003
Characterization of the in vitro anti-inflammatory activity of AL-5898 and related benzopyranyl esters and amides. David KC, Brady MT, Weimer LK, Hellberg MR, Nixon JC, Graff G	Inflammation	2003
Nf-kappa B, chemokine gene transcription and tumour growth A Richmond	Nature reviews. Immunology	2002
Perspectives for TNF-α-targeting therapies HM Lorenz, JR Kalden	Arthritis research	2002
Effect of Protein SV-IV on Experimental Salmonella enterica Serovar Typhimurium Infection in Mice C Romano-Carratelli, C Bentivoglio, I Nuzzo, N Benedetto, E Buommino, A Cozzolino, M Cartenì, F Morelli, MR Costanza, B Metafora, V Metafora, S Metafora	Clinical and vaccine immunology : CVI	2002
Nuclear Factor-κB Inhibitors as Potential Novel Anti-Inflammatory Agents for the Treatment of Immune Glomerulonephritis López-Franco O, Suzuki Y, Sanjuán G, Blanco J, Hernández-Vargas P, Yo Y, Kopp J, Egido J, Gómez-Guerrero C	The American Journal of Pathology	2002
Nuclear factor–kB: A key role in inflammatory diseases Paul Tak, Gary Firestein	Journal of Clinical Investigation	2001
Control of oncogenesis and cancer therapy resistance by the transcription factor NF-kB Albert Baldwin	Journal of Clinical Investigation	2001

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