Meth-A sarcoma cells were stable transfected to overexpress (sense construct) or underexpress (antisense construct) tissue factor. In vitro, there was no difference in plating efficiency or growth between these cell lines. In vivo, tumor cells transfected to overexpress tissue factor grew more rapidly, and established larger and more vascularized tumors than control transfectants. Antisense transfectants grew the slowest and were the least vascularized. Anticoagulation of mice with warfarin did not alter the difference between these tumor lines. Tumor cells over-expressing tissue factor released more (compared with control transfectants) mitogenic activity for endothelial cells in parallel with enhanced transcription of vascular permeability factor/vascular endothelial cell growth factor (VEGF/VPF), and diminished transcription of thrombospondin (TSP2), a molecule with anti-angiogenic properties. Antisense tissue factor transfectants, while releasing the lowest amount of mitogenic activity, had increased thrombospondin and decreased VEGF/VPF transcription compared with control transfectants or wild-type cells. Experiments with these sense, antisense, truncated sense, or vector tumor lines gave comparable results in complete medium, serum free medium or in the presence of hirudin, indicating that the activation of the coagulation mechanism was not likely to be responsible for changes in tumor cell properties. These results suggest that tissue factor regulates angiogenic properties of tumor cells by altering the production of growth regulatory molecules of endothelium by a mechanism distinct from tissue factor activation of the coagulation mechanism.
Y Zhang, Y Deng, T Luther, M Müller, R Ziegler, R Waldherr, D M Stern, P P Nawroth
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Vascular Endothelial Growth Factor (VEGF) as a Biomarker for Cancer-Associated Venous Thrombosis: A Meta-analysis
Brown AM, Nock S, Musgrave K, Unsworth AJ |
TH Open: Companion Journal to Thrombosis and Haemostasis | 2025 |
Tissue factor pathway inhibitor-2 (TFPI-2)-an underappreciated partaker in cancer and metastasis.
Wojtukiewicz MZ, Mysliwiec M, Tokajuk A, Kruszewska J, Politynska B, Jamroze A, Wojtukiewicz AM, Tang DG, Honn KV |
Cancer metastasis reviews | 2024 |
The Tissue Factor Pathway in Cancer: Overview and Role of Heparan Sulfate Proteoglycans.
Hassan N, Efing J, Kiesel L, Bendas G, Götte M |
Cancers | 2023 |
Tissue factor (coagulation factor III): a potential double-edge molecule to be targeted and re-targeted toward cancer.
Ahmadi SE, Shabannezhad A, Kahrizi A, Akbar A, Safdari SM, Hoseinnezhad T, Zahedi M, Sadeghi S, Mojarrad MG, Safa M |
Biomarker Research | 2023 |
Obesity: a perfect storm for carcinogenesis.
Harris BHL, Macaulay VM, Harris DA, Klenerman P, Karpe F, Lord SR, Harris AL, Buffa FM |
Cancer metastasis reviews | 2022 |
Tinzaparin-a review of its molecular profile, pharmacology, special properties, and clinical uses.
Amerali M, Politou M |
European Journal of Clinical Pharmacology | 2022 |
Expression of tissue factor and tissue factor pathway inhibitors during ovulation in rats: a relevance to the ovarian hyperstimulation syndrome
YJ Jang, HK Kim, BC Choi, SJ Song, JI Park, SY Chun, MK Cho |
Reproductive Biology and Endocrinology | 2021 |
An Integrated Approach of the Potential Underlying Molecular Mechanistic Paradigms of SARS-CoV-2-Mediated Coagulopathy
A Goyal, R Prasad, P Goel, A Pal, S Prasad, I Rani |
Indian Journal of Clinical Biochemistry | 2021 |
Coagulation in Lymphatic System
W Zhang, J Li, J Liang, X Qi, J Tian, J Liu |
Frontiers in Cardiovascular Medicine | 2021 |
Heterogeneous Expression of Proangiogenic and Coagulation Proteins in Gliomas of Different Histopathological Grade
MZ Wojtukiewicz, M Mysliwiec, E Matuszewska, S Sulkowski, L Zimnoch, B Politynska, AM Wojtukiewicz, SC Tucker, KV Honn |
Pathology oncology research : POR | 2021 |
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J Mao, B H Pan, H Yin, J Z Wu, Y Xia, L Wang, J Y Li, W Xu |
Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi | 2021 |
Heparanase: From Basic Research to Clinical Applications
I Vlodavsky, RD Sanderson, N Ilan |
2020 | |
Heparanase: From Basic Research to Clinical Applications
I Vlodavsky, RD Sanderson, N Ilan |
2020 | |
Heparanase: From Basic Research to Clinical Applications
I Vlodavsky, RD Sanderson, N Ilan |
2020 | |
Heparanase: From Basic Research to Clinical Applications
I Vlodavsky, RD Sanderson, N Ilan |
2020 | |
Heparanase: From Basic Research to Clinical Applications
I Vlodavsky, RD Sanderson, N Ilan |
2020 | |
Heparanase: From Basic Research to Clinical Applications
I Vlodavsky, RD Sanderson, N Ilan |
2020 | |
Heparanase: From Basic Research to Clinical Applications
I Vlodavsky, RD Sanderson, N Ilan |
2020 | |
Heparanase: From Basic Research to Clinical Applications
I Vlodavsky, RD Sanderson, N Ilan |
2020 | |
Heparanase: From Basic Research to Clinical Applications
I Vlodavsky, RD Sanderson, N Ilan |
2020 | |
Heparanase: From Basic Research to Clinical Applications
I Vlodavsky, RD Sanderson, N Ilan |
2020 | |
Heparanase: From Basic Research to Clinical Applications
I Vlodavsky, RD Sanderson, N Ilan |
2020 | |
Acute Leriche Syndrome in Pancreatic Adenocarcinoma: A Case Report
E Mosa, S Manouvelou, M Tolia, N Tsoukalas, A Ardavanis, M Stasinopoulou, G Kyrgias, A Tavernaraki |
Current Medical Imaging Reviews | 2020 |
Tissue Factor and Cancer: Regulation, Tumor Growth, and Metastasis
Y Hisada, N Mackman |
Seminars in thrombosis and hemostasis | 2019 |
NMR structure determination of Ixolaris and factor X(a) interaction reveals a noncanonical mechanism of Kunitz inhibition
VS Paula, NG Sgourakis, IM Francischetti, FC Almeida, RQ Monteiro, AP Valente |
Blood | 2019 |
Tissue factor activity on microvesicles from cancer patients
F Ender, A Freund, T Quecke, C Steidel, P Zamzow, N von Bubnoff, F Gieseler |
Journal of Cancer Research and Clinical Oncology | 2019 |
Rivaroxaban does not affect growth of human pancreatic tumors in mice
A Maqsood, Y Hisada, KB Garratt, J Homeister, N Mackman |
Journal of Thrombosis and Haemostasis | 2019 |
Tumor Clearance Analysis on a Cancer Chemo-Immunotherapy Mathematical Model
PA Valle, LN Coria, Y Salazar |
Bulletin of Mathematical Biology | 2019 |
The role of tissue factor in metastasising, neoangiogenesis and hemostasis in cancer
TA Kovalenko, MA Panteleev, AN Sveshnikova |
2019 | |
Clinical characteristics of disseminated intravascular coagulation in patients with solid and hematological cancers
M Levi |
Thrombosis Research | 2018 |
Uterine carcinosarcoma-induced pulmonary tumor thrombotic microangiopathy: A case report
T Hibiya, S Umeda, K Okudela, M Furuya, S Yamanaka, K Ohashi |
Human Pathology: Case Reports | 2018 |
Antibody drug conjugates under investigation in phase I and phase II clinical trials for gastrointestinal cancer
AD Leal, A Krishnamurthy, L Head, WA Messersmith |
Expert Opinion on Investigational Drugs | 2018 |
Tissue factor expression is associated with recurrence in patients with non-metastatic colorectal cancer
HJ Jung, HJ Kim, K Kaneko, Y Kazama, K Kawai, S Ishihara, GS Choi |
Korean Journal of Clinical Oncology | 2018 |
Tumor-Derived Tissue Factor Aberrantly Activates Complement and Facilitates Lung Tumor Progression via Recruitment of Myeloid-Derived Suppressor Cells
X Han, H Zha, F Yang, B Guo, B Zhu |
International journal of molecular sciences | 2017 |
Subacute Disseminated Intravascular Coagulation in a Patient with Liver Metastases of a Renal Cell Carcinoma
LC van der Wekken, RJ Loffeld |
Case Reports in Oncological Medicine | 2017 |
Thromboembolic Disease in Patients with Metastatic Femoral Lesions: A Comparison Between Prophylactic Fixation and Fracture Fixation
A Aneja, JJ Jiang, A Cohen-Rosenblum, HL Luu, TD Peabody, S Attar, TD Luo, RC Haydon |
The Journal of Bone and Joint Surgery. American volume. | 2017 |
The Angiogenic Secretome in VEGF overexpressing Breast Cancer Xenografts
L Dore-Savard, E Lee, S Kakkad, AS Popel, ZM Bhujwalla |
Scientific Reports | 2016 |
A critical balance: managing coagulation in patients with glioma
ER Morgan, WP Mason, C Maurice |
Expert Review of Neurotherapeutics | 2016 |
High pretreatment plasma D-dimer levels are related to shorter overall survival in endometrial carcinoma
K Nakamura, K Nakayama, M Ishikawa, H Katagiri, T Minamoto, T Ishibashi, N Ishikawa, E Sato, K Sanuki, H Yamashita, T Komatsu-Fujii, S Kyo |
European Journal of Obstetrics & Gynecology and Reproductive Biology | 2016 |
Management of cancer-associated disseminated intravascular coagulation
M Levi |
Thrombosis Research | 2016 |
Coexpression of heparanase activity, cathepsin L, tissue factor, tissue factor pathway inhibitor, and MMP-9 in proliferative diabetic retinopathy
Ahmed M Abu El-Asrar, Mohammad Mairaj Siddiquei, Mohd Imtiaz Nawaz, Gert De Hertogh, Ghulam Mohammad, Kaiser Alam, Ahmed Mousa, Ghislain Opdenakker |
Molecular vision | 2016 |
Forsythiae Fructus Induces VEGF Production via p38 MAPK Activation in Human Keratinocytes
MS Kim, YH Choi, SG Park, CK Lee, SH Lee |
Journal of the Society of Cosmetic Scientists of Korea | 2016 |
Imatinib Alleviated Pulmonary Hypertension Caused by Pulmonary Tumor Thrombotic Microangiopathy in a Patient With Metastatic Breast Cancer
I Fukada, K Araki, S Minatsuki, T Fujino, M Hatano, S Numakura, H Abe, T Ushiku, T Iwase, Y Ito |
Clinical Breast Cancer | 2015 |
Visualizing cancer and response to therapy in vivo using Cy5.5-labeled factor VIIa and anti-tissue factor antibody
S Zhu, W Kisiel, YJ Lu, LC Petersen, JM Ndungu, TW Moore, ET Parker, A Sun, JN Sarkaria, JP Snyder, DC Liotta, DJ Brat, BF El-Rayes, M Shoji |
Journal of Drug Targeting | 2015 |
Small Animal Critical Care Medicine
AG Ralph, BM Brainard |
Small Animal Critical Care Medicine | 2015 |
Preoperative D-dimers as an independent prognostic marker in cervical carcinoma
YL Luo, PD Chi, X Zheng, L Zhang, XP Wang, H Chen |
Tumor Biology | 2015 |
Changes in the Laboratory Data for Cancer Patients Treated with Korean-medicine-based Inpatient Care
J Yoon, CK Cho, JE Shin, HS Yoo |
Journal of Pharmacopuncture | 2014 |
Extracellular architecture of the SYG-1/SYG-2 adhesion complex instructs synaptogenesis.
Özkan E, Chia PH, Wang RR, Goriatcheva N, Borek D, Otwinowski Z, Walz T, Shen K, Garcia KC |
Cell | 2014 |
Role of the protein C receptor in cancer progression.
Ruf W, Schaffner F |
Thrombosis Research | 2014 |
γδ T cells recognize the insulin B:9-23 peptide antigen when it is dimerized through thiol oxidation.
Aydintug MK, Zhang L, Wang C, Liang D, Wands JM, Michels AW, Hirsch B, Day BJ, Zhang G, Sun D, Eisenbarth GS, O'Brien RL, Born WK |
Molecular Immunology | 2014 |
Phosphorylation of sterol regulatory element binding protein-1a by protein kinase A (PKA) regulates transcriptional activity.
Dong Q, Giorgianni F, Deng X, Beranova-Giorgianni S, Bridges D, Park EA, Raghow R, Elam MB |
Biochemical and Biophysical Research Communications | 2014 |
Challenges associated with Penetration of Nanoparticles across Cell and Tissue Barriers: A Review of Current Status and Future Prospects
Barua S, Mitragotri S |
Nano Today | 2014 |
The role of β cell glucagon-like peptide-1 signaling in glucose regulation and response to diabetes drugs.
Smith EP, An Z, Wagner C, Lewis AG, Cohen EB, Li B, Mahbod P, Sandoval D, Perez-Tilve D, Tamarina N, Philipson LH, Stoffers DA, Seeley RJ, D'Alessio DA |
Cell Metabolism | 2014 |
Osteopontin facilitates ultraviolet B-induced squamous cell carcinoma development.
Chang PL, Hsieh YH, Wang CC, Juliana MM, Tsuruta Y, Timares L, Elmets C, Ho KJ |
Journal of Dermatological Science | 2014 |
Immunohistochemical evaluation of tissue factor, fibrin/fibrinogen and D-dimers in canine gliomas
C la Fuente, M Pumarola, E Blasco, F Fernández, J Viu, S Añor |
The Veterinary Journal | 2014 |
Mutations in NSCLC and their link with lung cancer-associated thrombosis: A case-control study
L Corrales-Rodriguez, D Soulières, X Weng, M Tehfe, M Florescu, N Blais |
Thrombosis Research | 2014 |
Tumor Angiogenesis Therapy Using Targeted Delivery of Paclitaxel to the Vasculature of Breast Cancer Metastases
S Zhu, W Kisiel, YJ Lu, LC Petersen, JM Ndungu, TW Moore, ET Parker, A Sun, DC Liotta, BF El-Rayes, DJ Brat, JP Snyder, M Shoji |
Journal of drug delivery | 2014 |
Heparins and cancer survival: where do we stand?
S Noble |
Thrombosis Research | 2014 |
Cancer-related coagulopathies
M Levi |
Thrombosis Research | 2014 |
Effect of resection of localized pancreaticobiliary adenocarcinoma on angiogenic markers and tissue factor related pro-thrombotic and pro-angiogenic activity
HH Echrish, Y Xiao, LA Madden, V Allgar, J Cooke, K Wedgwood, D Dasgupta, J Greenman, A Maraveyas |
Thrombosis Research | 2014 |
Symptomatic and Incidental Venous Thromboembolic Disease Are Both Associated with Mortality in Patients with Prostate Cancer
S Chaturvedi, S Sidana, P Elson, AA Khorana, KR McCrae, H Cate |
PloS one | 2014 |
Activation of blood coagulation in cancer: implications for tumour progression
LG Lima, RQ Monteiro |
Bioscience Reports | 2013 |
Platelet-derived growth factor-A and vascular endothelial growth factor-C contribute to the development of pulmonary tumor thrombotic microangiopathy in gastric cancer
H Abe, R Hino, M Fukayama |
Virchows Archiv | 2013 |
Tumour necrosis factor and cancer: TNF and cancer
JP Waters, JS Pober, JR Bradley |
The Journal of Pathology | 2013 |
Age-related macular degeneration (AMD): Current concepts in pathogenesis and prospects for treatment
OR Shin, YH Kim |
Tissue Engineering and Regenerative Medicine | 2013 |
Upregulation of tissue factor by activated Stat3 contributes to malignant pleural effusion generation via enhancing tumor metastasis and vascular permeability in lung adenocarcinoma
HH Yeh, WT Chang, KC Lu, WW Lai, HS Liu, WC Su |
PloS one | 2013 |
Upregulation of Tissue Factor by Activated Stat3 Contributes to Malignant Pleural Effusion Generation via Enhancing Tumor Metastasis and Vascular Permeability in Lung Adenocarcinoma
HH Yeh, WT Chang, KC Lu, WW Lai, HS Liu, WC Su, VV Kalinichenko |
PloS one | 2013 |
Cytochalasin D promotes pulmonary metastasis of B16 melanoma through expression of tissue factor
FY Huang, WL Mei, GH Tan, HF Dai, YN Li, JL Guo, YH Huang, HG Zhao, H Wang, SL Zhou, YY Lin |
Oncology reports | 2013 |
Tissue factor-bearing exosome secretion from human mechanically-stimulated bronchial epithelial cells in vitro and in vivo
JA Park, AS Sharif, DJ Tschumperlin, L Lau, R Limbrey, P Howarth, JM Drazen |
Journal of Allergy and Clinical Immunology | 2012 |
Inhibition of tissue factor by ixolaris reduces primary tumor growth and experimental metastasis in a murine model of melanoma
AD de Oliveira, LG Lima, A Mariano-Oliveira, DE Machado, LE Nasciutti, JF Andersen, LC Petersen, IM Francischetti, RQ Monteiro |
Thrombosis Research | 2012 |
Lung cancer associated venous thromboembolic disease: A comprehensive review
L Corrales-Rodriguez, N Blais |
Lung Cancer | 2012 |
Thrombosis and cancer: 40years of research
MB Donati, R Lorenzet |
Thrombosis Research | 2012 |
Tissue factor isoforms in cancer and coagulation: May the best isoform win
B Kocatürk, HH Versteeg |
Thrombosis Research | 2012 |
Genetic pathways linking hemostasis and cancer
D Garnier, N Magnus, E D'Asti, M Hashemi, B Meehan, C Milsom, J Rak |
Thrombosis Research | 2012 |
Oncogenic regulation of tissue factor and thrombosis in cancer
M Anand, DJ Brat |
Thrombosis Research | 2012 |
Tissue factor and cancer
W Ruf |
Thrombosis Research | 2012 |
Tissue factor pathway inhibitor as a multifunctional mediator of vascular structure
EW Holroyd, TA White, S Pan, RD Simari |
Frontiers in bioscience (Elite edition) | 2012 |
Endometriosis, Angiogenesis and Tissue Factor
G Krikun |
Scientifica | 2012 |
Protease-activated receptor 2 signaling in inflammation
AS Rothmeier, W Ruf |
Seminars in Immunopathology | 2011 |
The Hemostasis Apparatus in Pancreatic Cancer and Its Importance beyond Thrombosis
H Echrish, LA Madden, J Greenman, A Maraveyas |
Cancers | 2011 |
The role of blood platelets in tumor angiogenesis
S Sabrkhany, AW Griffioen, MG Egbrink |
Biochimica et Biophysica Acta (BBA) - Reviews on Cancer | 2011 |
All trans-retinoic acid modulates the procoagulant activity of human breast cancer cells
M Marchetti, L Russo, D Balducci, A Falanga |
Thrombosis Research | 2011 |
The relationship between tissue factor and cancer progression: insights from bench and bedside
YW van Berg, S Osanto, PH Reitsma, HH Versteeg |
Blood | 2011 |
Inhibition of the renin-angiotensin system downregulates tissue factor and vascular endothelial growth factor in human breast carcinoma cells
E Napoleone, A Cutrone, D Cugino, C Amore, AD Santo, L Iacoviello, G Gaetano, MB Donati, R Lorenzet |
Thrombosis Research | 2011 |
Pancreatic cancer cell and microparticle procoagulant surface characterization : involvement of membrane-expressed tissue factor, phosphatidylserine and phosphatidylethanolamine
KR Yates, J Welsh, HH Echrish, J Greenman, A Maraveyas, LA Madden |
Blood Coagulation & Fibrinolysis | 2011 |
Advances in Pancreatic Cancer Treatment
JM Löhr, SL Haas, R Heuchel |
Advances in Pancreatic Cancer Treatment | 2011 |
D-dimer levels as a prognostic factor for determining oncological outcomes in musculoskeletal sarcoma
T Morii, K Mochizuki, T Tajima, S Ichimura, K Satomi |
BMC musculoskeletal disorders | 2011 |
Blood coagulation and blood vessel development: is tissue factor the missing link?
N Mackman, GE Davis |
Arteriosclerosis, thrombosis, and vascular biology | 2011 |
Anticoagulants, Antiplatelets, and Thrombolytics
SA Mousa |
2010 | |
Anticoagulants, Antiplatelets, and Thrombolytics
SA Mousa |
2010 | |
Anticoagulants, Antiplatelets, and Thrombolytics
SA Mousa |
2010 | |
Anticoagulants, Antiplatelets, and Thrombolytics
SA Mousa |
2010 | |
Anticoagulants, Antiplatelets, and Thrombolytics
SA Mousa |
2010 | |
Anticoagulants, Antiplatelets, and Thrombolytics
SA Mousa |
2010 | |
Anticoagulants, Antiplatelets, and Thrombolytics
SA Mousa |
2010 | |
Erythropoiesis stimulating agents, thrombosis and cancer
L Barbera, G Thomas |
Radiotherapy and Oncology | 2010 |
Antithrombotic therapy and survival in patients with malignant disease
AK Kakkar, F Macbeth |
British Journal of Cancer | 2010 |
Oncogenic epidermal growth factor receptor up-regulates multiple elements of the tissue factor signaling pathway in human glioma cells
N Magnus, D Garnier, J Rak |
Blood | 2010 |
Anti-tissue factor short hairpin RNA inhibits breast cancer growth in vivo
JE Bluff, M Amarzguioui, J Slattery, MW Reed, NJ Brown, CA Staton |
Breast Cancer Research and Treatment | 2010 |
Angiogenesis and development of adipose tissue
V Christiaens, HR Lijnen |
Molecular and Cellular Endocrinology | 2010 |
The potential pathophysiological role of tissue factor in age-related macular degeneration
Y Cho, FR Rickles, LM Parver, J Tuo, CC Chan |
Expert Review of Ophthalmology | 2010 |
Evidence for Enhanced Tissue Factor Expression in Age-related Macular Degeneration
Y Cho, X Cao, DF Shen, J Tuo, LM Parver, FR Rickles, CC Chan |
Laboratory Investigation | 2010 |
Vitamins & Hormones
KJ Hare, FK Knop |
Vitamins & Hormones | 2010 |
Immunolocalisation of tissue factor in esophageal cancer is correlated with intratumoral angiogenesis and prognosis of the patient
L Chen, G Luo, Y Tan, J Wei, C Wu, L Zheng, X Zhang, N Xu |
Acta Histochemica | 2010 |
Pulmonary tumor thrombotic microangiopathy in patients with gastric carcinoma: An analysis of 6 autopsy cases and review of the literature
K Chinen, Y Tokuda, M Fujiwara, Y Fujioka |
Pathology - Research and Practice | 2010 |
Binding of Anti-GRP78 Autoantibodies to Cell Surface GRP78 Increases Tissue Factor Procoagulant Activity via the Release of Calcium from Endoplasmic Reticulum Stores
AA Al-Hashimi, J Caldwell, M Gonzalez-Gronow, SV Pizzo, D Aboumrad, L Pozza, H Al-Bayati, JI Weitz, A Stafford, H Chan, A Kapoor, DW Jacobsen, JG Dickhout, RC Austin |
The Journal of biological chemistry | 2010 |
Targeted Knockdown of Tissue Factor in B16F10 Melanoma Cells suppresses their Ability to Metastasize to Bone and cause cancellous Bone Loss
A Politano, M Butcher, M Zeadin, P Gross, N Vaezzadeh, SG Shaughnessy |
Cancer Growth and Metastasis | 2010 |
Metastasis of Colorectal Cancer
N Beauchemin, J Huot |
2010 | |
Coagulation in Cancer
HC Kwaan, D Green |
2009 | |
Coagulation in Cancer
HC Kwaan, D Green |
2009 | |
Coagulation in Cancer
HC Kwaan, D Green |
2009 | |
Coagulation in Cancer
HC Kwaan, D Green |
2009 | |
Coagulation in Cancer
HC Kwaan, D Green |
2009 | |
Coagulation in Cancer
HC Kwaan, D Green |
2009 | |
Coagulation in Cancer
HC Kwaan, D Green |
2009 | |
Coagulation in Cancer
HC Kwaan, D Green |
2009 | |
Coagulation in Cancer
HC Kwaan, D Green |
2009 | |
Coagulation in Cancer
HC Kwaan, D Green |
2009 | |
Role of Tissue Factor in the Maternal Immunological Attack of the Embryo in the Antiphospholipid Syndrome
G Girardi |
Clinical Reviews in Allergy & Immunology | 2009 |
Disseminated intravascular coagulation in cancer patients
M Levi |
Best Practice & Research Clinical Haematology | 2009 |
A Case of Cerebral Venous Thrombosis as the Presenting Sign of Occult Prostate Cancer
SS Lee, SH Baek, DI Shin |
Journal of Clinical Neurology | 2009 |
Ixolaris, a tissue factor inhibitor, blocks primary tumor growth and angiogenesis in a glioblastoma model
TC Carneiro-Lobo, S Konig, DE Machado, LE Nasciutti, MF Forni, IM Francischetti, MC Sogayar, RQ Monteiro |
Journal of Thrombosis and Haemostasis | 2009 |
Tumors, ticks and tissue factor
T McEachron, N Mackman |
Journal of Thrombosis and Haemostasis | 2009 |
Angiogenesis is associated with the onset of hyperplasia in human ductal breast disease
JE Bluff, SR Menakuru, SS Cross, SE Higham, SP Balasubramanian, NJ Brown, MW Reed, CA Staton |
British Journal of Cancer | 2009 |
Tumor cells expressing tissue factor influence the migration of smooth muscle cells in a catalytic activity-dependent way
C Brousseau, G Morissette, JP Fortin, F Marceau, E Petitclerc |
Canadian Journal of Physiology and Pharmacology | 2009 |
Thrombosis associated with angiogenesis inhibitors
F Elice, F Rodeghiero, A Falanga, FR Rickles |
Best Practice & Research Clinical Haematology | 2009 |
Tissue factor in tumour progression
J Rak, C Milsom, N Magnus, J Yu |
Best Practice & Research Clinical Haematology | 2009 |
Clinical outcomes and factors predicting development of venous thromboembolic complications in patients with advanced refractory cancer in a Phase I Clinic: The M. D. Anderson Cancer Center experience
S Vemulapalli, L Chintala, AM Tsimberidou, N Dhillon, X Lei, D Hong, R Kurzrock |
American Journal of Hematology | 2009 |
Impact of venous thromboembolism and anticoagulation on cancer and cancer survival
NM Kuderer, TL Ortel, CW Francis |
Journal of Clinical Oncology | 2009 |
Role of tissue factor in cancer
RS Kasthuri, MB Taubman, N Mackman |
Journal of Clinical Oncology | 2009 |
Tissue Factor Pathway Inhibitor [Tfpi]: A Natural Coagulation Inhibitor and Potential Therapeutic Agent – A Review
AG Gader |
Journal of Taibah University Medical Sciences | 2009 |
Tissue Factor and VEGF Expression in Prostate Carcinoma: A Tissue Microarray Study
JL Yao, CK Ryan, CW Francis, M Kohli, MB Taubman, AA Khorana |
Cancer Investigation | 2009 |
Role of Tissue Factor in Cancer
KE Menzies, N Mackman, MB Taubman |
Cancer Investigation | 2009 |
Impact of Venous Thromboembolism and Anticoagulation on Cancer and Cancer Survival
NM Kuderer, TL Ortel, CW Francis |
Journal of Clinical Oncology | 2009 |
Hypercoagulability as a prognostic factor for survival in patients with metastatic renal cell carcinoma
IV Tsimafeyeu, LV Demidov, AV Madzhuga, OV Somonova, AL Yelizarova |
Journal of Experimental & Clinical Cancer Research | 2009 |
Targeting tissue factor-expressing tumor angiogenesis and tumors with EF24 conjugated to factor VIIa
M Shoji, A Sun, W Kisiel, YJ Lu, H Shim, BE McCarey, C Nichols, ET Parker, J Pohl, CA Mosley, AR Alizadeh, DC Liotta, JP Snyder |
Journal of Drug Targeting | 2008 |
Fundamental and Clinical Cardiology Series
PD Stein |
Cardiovascular Disease in the Elderly | 2008 |
Phospholipid composition of in vitro endothelial microparticles and their in vivo thrombogenic properties
MN Hussein, AN Böing, É Biró, FJ Hoek, GM Vogel, DG Meuleman, A Sturk, R Nieuwland |
Thrombosis Research | 2008 |
CARDIAC TISSUE FACTOR: ROLES IN PHYSIOLOGY AND FIBROSIS
DR Davis, JH Erlich |
Clinical and Experimental Pharmacology and Physiology | 2008 |
Vascular determinants of cancer stem cell dormancy-do age and coagulation system play a role?
J Rak, C Milsom, J Yu |
APMIS | 2008 |
Investigation of the mechanisms of tissue factor-mediated evasion of tumour cells from cellular cytotoxicity
C Li, ME Collier, GA Frentzou, J Greenman, C Ettelaie |
Cancer Immunology, Immunotherapy | 2008 |
Tissue Factor Expression in Non-small Cell Lung Cancer: Relationship with Vascular Endothelial Growth Factor Expression, Microvascular Density, and K-ras Mutation
S Regina, J Rollin, C Bléchet, S Iochmann, P Reverdiau, Y Gruel |
Journal of Thoracic Oncology | 2008 |
Tissue factor in cancer
J Rak, C Milsom, J Yu |
Current Opinion in Hematology | 2008 |
TF:FVIIa-specific activation of CREB upregulates proapoptotic proteins via protease-activated receptor-2
HH Versteeg, KS Borensztajn, ME Kerver, W Ruf, PH Reitsma, CA Spek, MP Peppelenbosch |
Journal of Thrombosis and Haemostasis | 2008 |
Hemostatic complications of angiogenesis inhibitors in cancer patients
F Elice, J Jacoub, FR Rickles, A Falanga, F Rodeghiero |
American Journal of Hematology | 2008 |
Tissue factor regulation by epidermal growth factor receptor and epithelial-to-mesenchymal transitions: effect on tumor initiation and angiogenesis
CC Milsom, JL Yu, N Mackman, J Micallef, GM Anderson, A Guha, JW Rak |
Cancer research | 2008 |
Use of mouse models to study the role of tissue factor in tumor biology
R Pawlinski, N Mackman |
Seminars in thrombosis and hemostasis | 2008 |
Tissue factor, angiogenesis and tumour progression
JE Bluff, NJ Brown, MW Reed, CA Staton |
Breast Cancer Research | 2008 |
Tissue factor/FVIIa activates Bcl-2 and prevents doxorubicin-induced apoptosis in neuroblastoma cells
J Fang, L Gu, N Zhu, H Tang, CS Alvarado, M Zhou |
BMC Cancer | 2008 |
Contribution of Host-Derived Tissue Factor to Tumor Neovascularization
J Yu, L May, C Milsom, GM Anderson, JI Weitz, JP Luyendyk, G Broze, N Mackman, J Rak |
Arteriosclerosis, thrombosis, and vascular biology | 2008 |
Selected Aspects of Cancer Progression: Metastasis, Apoptosis and Immune Response
HE Kaiser, A Nasir |
2008 | |
Expression of Tissue Factor in Prostate Cancer Correlates With Malignant Phenotype
V Kaushal, P Mukunyadzi, ER Siegel, RA Dennis, DE Johnson, M Kohli |
Applied Immunohistochemistry & Molecular Morphology | 2008 |
Protease-Activated Receptor (PAR) 2, but not PAR1, Signaling Promotes the Development of Mammary Adenocarcinoma in Polyoma Middle T Mice
HH Versteeg, F Schaffner, M Kerver, LG Ellies, P Andrade-Gordon, BM Mueller, W Ruf |
Cancer research | 2008 |
Trousseau Syndrome Due to Pleural Mesothelioma
H Matsui, K Nishinaka, M Oda, T Kubori, F Udaka |
The Neurologist | 2007 |
Extracellular RNA constitutes a natural procoagulant cofactor in blood coagulation
C Kannemeier, A Shibamiya, F Nakazawa, H Trusheim, C Ruppert, P Markart, Y Song, E Tzima, E Kennerknecht, M Niepmann, ML Bruehl, D Sedding, S Massberg, A Günther, B Engelmann, KT Preissner |
Proceedings of the National Academy of Sciences | 2007 |
Inhibition of tissue factor signaling suppresses tumor growth
HH Versteeg, F Schaffner, M Kerver, HH Petersen, J Ahamed, B Felding-Habermann, Y Takada, BM Mueller, W Ruf |
Blood | 2007 |
Tissue factor expression as a possible determinant of thromboembolism in ovarian cancer
K Uno, S Homma, T Satoh, K Nakanishi, D Abe, K Matsumoto, A Oki, H Tsunoda, I Yamaguchi, T Nagasawa, H Yoshikawa, K Aonuma |
British Journal of Cancer | 2007 |
Cancer-associated thrombosis
JI Zwicker, BC Furie, B Furie |
Critical Reviews in Oncology/Hematology | 2007 |
Tissue factor and vascular endothelial growth factor expression in colorectal cancer: relation with cancer recurrence
DF Altomare, MT Rotelli, A Pentimone, MR Rossiello, E Martinelli, A Guglielmi, MD Fazio, F Marino, V Memeo, M Colucci, N Semeraro |
Colorectal Disease | 2007 |
CNTO 859, a humanized anti-tissue factor monoclonal antibody, is a potent inhibitor of breast cancer metastasis and tumor growth in xenograft models
CV Ngo, K Picha, F McCabe, H Millar, R Tawadros, SH Tam, MT Nakada, GM Anderson |
International Journal of Cancer | 2007 |
Prothrombotic effect of prostasomes of metastatic cell and seminal origin
AA Babiker, OA Hamad, J Sanchez, G Ronquist, B Nilsson, KN Ekdahl |
The Prostate | 2007 |
Fat poetry: a kingdom for PPARγ
SI Anghel, W Wahli |
Cell Research | 2007 |
Fibronectin-adherent monocytes express tissue factor and tissue factor pathway inhibitor whereas endotoxin-stimulated monocytes primarily express tissue factor: physiologic and pathologic implications
MS Bajaj, M Ghosh, SP Bajaj |
Journal of Thrombosis and Haemostasis | 2007 |
Redundant signaling of tissue factor and thrombin in cancer progression?
W Ruf |
Journal of Thrombosis and Haemostasis | 2007 |
Low molecular weight heparins in cancer patients: to treat thromboembolic events, the tumor, or both?
S Siragusa |
Oncology Reviews | 2007 |
Increase in expression of monocytic tissue factor (CD142) with monocytes and blood platelet activation in liver cirrhosis
A Panasiuk, J Zak, B Panasiuk, D Prokopowicz |
Blood Coagulation & Fibrinolysis | 2007 |
Tissue factor expression correlates with disease-specific survival in patients with node-negative muscle-invasive bladder cancer
G Patry, H Hovington, H Larue, F Harel, Y Fradet, L Lacombe |
International Journal of Cancer | 2007 |
The angiogenic switch occurs at the adenoma stage of the adenoma carcinoma sequence in colorectal cancer
CA Staton, AS Chetwood, IC Cameron, SS Cross, NJ Brown, MW Reed |
Gut | 2007 |
Heparanase, heparin and the coagulation system in cancer progression
I Vlodavsky, N Ilan, Y Nadir, B Brenner, BZ Katz, A Naggi, G Torri, B Casu, R Sasisekharan |
Thrombosis Research | 2007 |
The effects of low molecular weight heparins on venous thromboembolism and survival in patients with cancer
AY Lee |
Thrombosis Research | 2007 |
Tissue factor and PAR signaling in tumor progression
W Ruf |
Thrombosis Research | 2007 |
The role of tumor-and host-related tissue factor pools in oncogene-driven tumor progression
C Milsom, J Yu, L May, B Meehan, N Magnus, K Al-Nedawi, J Luyendyk, J Weitz, P Klement, G Broze, N Mackman, J Rak |
Thrombosis Research | 2007 |
A novel anti-tissue factor monoclonal antibody with anticoagulant potency derived from synthesized multiple antigenic peptide through blocking FX combination with TF
ZC Peng, X Cai, YG Zhang, DS Kong, HS Guo, W Liang, QQ Tang, HY Song, D Ma |
Thrombosis Research | 2007 |
Cancer-Associated Thrombosis: New Findings in Translational Science, Prevention, and Treatment
G Petralia, A Kakkar |
Cancer-Associated Thrombosis: New Findings in Translational Science, Prevention, and Treatment | 2007 |
Venous Thromboembolism and Cancer
D Bergqvist, JA Caprini, O Dotsenko, AK Kakkar, RG Mishra, TW Wakefield |
Current Problems in Surgery | 2007 |
Eosinophils are a major intravascular location for tissue factor storage and exposure
C Moosbauer, E Morgenstern, SL Cuvelier, D Manukyan, K Bidzhekov, S Albrecht, P Lohse, KD Patel, B Engelmann |
Blood | 2006 |
Elevation of plasma tissue factor levels in patients with severe acute pancreatitis
H Sawa, T Ueda, Y Takeyama, T Yasuda, N Matsumura, T Nakajima, T Ajiki, Y Fujino, Y Suzuki, Y Kuroda |
Journal of Gastroenterology | 2006 |
The pathogenesis of venous thromboembolism in cancer: emerging links with tumour biology
PC Winter |
Hematological Oncology | 2006 |
Heparanase induces tissue factor expression in vascular endothelial and cancer cells
Y Nadir, B Brenner, A Zetser, N Ilan, I Shafat, E Zcharia, O Goldshmidt, I Vlodavsky |
Journal of Thrombosis and Haemostasis | 2006 |
Grateloupia longifolia polysaccharide inhibits angiogenesis by downregulating tissue factor expression in HMEC-1 endothelial cells
C Zhang, F Yang, XW Zhang, SC Wang, MH Li, LP Lin, J Ding |
British Journal of Pharmacology | 2006 |
Low-molecular-weight heparins and angiogenesis
K Norrby |
APMIS | 2006 |
Identification and characterization of murine alternatively spliced tissue factor
VY Bogdanov, RI Kirk, C Miller, JJ Hathcock, S Vele, M Gazdoiu, Y Nemerson, MB Taubman |
Journal of Thrombosis and Haemostasis | 2006 |
VEGF Expression in Human Glioma Cells Treated with Tissue Factor and FVIIa
SB Smolik, G Powell |
Journal of Neurosurgical Anesthesiology | 2006 |
Evaluation of plasma tissue factor and tissue factor pathway inhibitor levels in childhood hemangiomas
M Türker, G İrken, H Ören, Ş Yılmaz, F Yüksel, N Olgun |
Pediatric Blood & Cancer | 2006 |
Tumour-expressed tissue factor inhibits cellular cytotoxicity
C Li, LM Colman, ME Collier, CE Dyer, J Greenman, C Ettelaie |
Cancer Immunology, Immunotherapy | 2006 |
Treatment of Cancer-Associated Thrombosis: Distinguishing Among Antithrombotic Agents
J Pruemer |
Seminars in Oncology | 2006 |
Circulating endothelial cells, endothelial progenitor cells, and endothelial microparticles in cancer
PK Goon, GY Lip, CJ Boos, PS Stonelake, AD Blann |
Neoplasia (New York, N.Y.) | 2006 |
Tissue factor and tumor: Clinical and laboratory aspects
Y Förster, A Meye, S Albrecht, B Schwenzer |
Clinica Chimica Acta | 2006 |
Expression of tissue factor in pancreatic adenocarcinoma is associated with activation of coagulation
SL Haas, R Jesnowski, M Steiner, F Hummel, J Ringel, C Burstein, H Nizze, S Liebe, JM Löhr |
World journal of gastroenterology : WJG | 2006 |
Thrombosis and Cancer: The Role of Screening for Occult Cancer and Recognizing the Underlying Biological Mechanisms
AY Lee |
Hematology / the Education Program of the American Society of Hematology. American Society of Hematology. Education Program | 2006 |
Ovarian cancer, the coagulation pathway, and inflammation
X Wang, E Wang, JJ Kavanagh, RS Freedman |
Journal of Translational Medicine | 2005 |
Angiostatin is a novel anti-inflammatory factor by inhibiting leukocyte recruitment
T Chavakis, A Athanasopoulos, JS Rhee, V Orlova, T Schmidt-Wöll, A Bierhaus, AE May, I Celik, PP Nawroth, KT Preissner |
Blood | 2005 |
Anti-thrombotics in thrombosis and cancer
SA Mousa |
Future Oncology | 2005 |
Pulmonary tumor thrombotic microangiopathy caused by a gastric carcinoma expressing vascular endothelial growth factor and tissue factor
K Chinen, T Kazumoto, Y Ohkura, O Matsubara, E Tsuchiya |
Pathology International | 2005 |
ANGIOGENESIS, CHOROIDAL NEOVASCULARIZATION, AND THE COAGULATION SYSTEM
GL Stoller, SA Mousa |
Retina | 2005 |
Angiogenesis: update 2005
HF Dvorak |
Journal of Thrombosis and Haemostasis | 2005 |
Radiotherapy of Human Xenograft NSCLC Tumors in Nude Mice with a90Y-Labeled Anti-Tissue Factor Antibody
B Wang, M Berger, G Masters, E Albone, Q Yang, J Sheedy, Y Kirksey, L Grimm, B Wang, J Singleton, D Soltis |
Cancer Biotherapy & Radiopharmaceuticals | 2005 |
Venous Thromboembolism in Patients with Cancer and Its Relationship to the Coagulation Cascade and Vascular Endothelial Growth Factor
M Dogan, A Demirkazik |
Supportive Cancer Therapy | 2005 |
Cancer Gene Therapy
M Yamamoto, DT Curiel |
Technology in cancer research & treatment | 2005 |
Tissue Factor–Factor VIIa Signaling
LV Rao, UR Pendurthi |
Arteriosclerosis, thrombosis, and vascular biology | 2005 |
New Mechanisms for Tissue-Selective Estrogen-Free Contraception
HB Croxatto, R Schürmann, U Fuhrmann, I Schellschmidt |
2005 | |
Mechanisms of Disease: the impact of antithrombotic therapy in cancer patients
GA Petralia, NR Lemoine, AK Kakkar |
Nature clinical practice. Oncology | 2005 |
Rapamycin induces tumor-specific thrombosis via tissue factor in the presence of VEGF
M Guba, M Yezhelyev, ME Eichhorn, G Schmid, I Ischenko, A Papyan, C Graeb, H Seeliger, EK Geissler, KW Jauch, CJ Bruns |
Blood | 2005 |
Oncogenic events regulate tissue factor expression in colorectal cancer cells: implications for tumor progression and angiogenesis
JL Yu, L May, V Lhotak, S Shahrzad, S Shirasawa, JI Weitz, BL Coomber, N Mackman, JW Rak |
Blood | 2004 |
Manipulating angiogenesis in medicine
P Carmeliet |
Journal of Internal Medicine | 2004 |
Genetic dissection of tumor angiogenesis: are PlGF and VEGFR-1 novel anti-cancer targets?
A Luttun, M Autiero, M Tjwa, P Carmeliet |
Biochimica et Biophysica Acta (BBA) - Reviews on Cancer | 2004 |
The prothrombotic state in cancer: pathogenic mechanisms
MD Cicco |
Critical Reviews in Oncology/Hematology | 2004 |
Pancreatic cancer and thromboembolic disease
AA Khorana, RL Fine |
The Lancet Oncology | 2004 |
Tissue factor in neutrophils: yes
S Nakamura, T Imamura, K Okamoto |
Journal of Thrombosis and Haemostasis | 2004 |
Downregulation of tissue factor by RNA interference in human melanoma LOX-L cells reduces pulmonary metastasis in nude mice
X Wang, M Wang, M Amarzguioui, F Liu, Ø Fodstad, H Prydz |
International Journal of Cancer | 2004 |
Circulating endothelial cells in cancer patients do not express tissue factor
LV Beerepoot, N Mehra, F Linschoten, AS Jorna, T Lisman, HM Verheul, EE Voest |
Cancer Letters | 2004 |
Tissue factor
CA Spek |
Blood Coagulation & Fibrinolysis | 2004 |
Reduction in Arthritis Severity and Modulation of Immune Function in Tissue Factor Cytoplasmic Domain Mutant Mice
YH Yang, P Hall, G Milenkovski, L Sharma, P Hutchinson, E Melis, P Carmeliet, P Tipping, E Morand |
The American Journal of Pathology | 2004 |
Tissue factor and cancer metastasis: the role of intracellular and extracellular signaling pathways
HH Versteeg, CA Spek, MP Peppelenbosch, DJ Richel |
Molecular Medicine | 2004 |
Antitumor and antimetastatic effect of warfarin and heparins
V Bobek, J Kovařík |
Biomedicine & Pharmacotherapy | 2004 |
Patogenia de la trombosis asociada a enfermedades neoplásicas: implicaciones terapéuticas
C López-Pedrera, N Barbarroja, F Velasco |
Medicina Clínica | 2004 |
Thrombosis and Cancer: A Case for Tissue Factor
M Donati, R Lorenzet |
Thrombosis and Cancer | 2004 |
Deep Vein Thrombosis and Malignancy: A Surgical Oncologist's Perspective
KP Yap, DR McCready |
Asian Journal of Surgery | 2004 |
Heparin is much more than just an anticoagulant
JR Day, RC Landis, KM Taylor |
Journal of Cardiothoracic and Vascular Anesthesia | 2004 |
Tumor necrosis factor activates CRE-binding protein through a p38 MAPK/MSK1 signaling pathway in endothelial cells
JA Gustin, R Pincheira, LD Mayo, ON Ozes, KM Kessler, MR Baerwald, CK Korgaonkar, DB Donner |
American journal of physiology. Cell physiology | 2004 |
Cross-talk of Integrin α3β1 and Tissue Factor in Cell Migration
A Dorfleutner, E Hintermann, T Tarui, Y Takada, W Ruf |
Molecular biology of the cell | 2004 |
The Janus-faced nature of prostasomes: their pluripotency favours the normal reproductive process and malignant prostate growth
G Ronquist, BO Nilsson |
Prostate Cancer and Prostatic Diseases | 2004 |
Role of endogenous thrombin in tumor implantation, seeding, and spontaneous metastasis
L Hu, M Lee, W Campbell, R Perez-Soler, S Karpatkin |
Blood | 2004 |
Mathematical modeling of tumor-induced angiogenesis
NV Mantzaris, S Webb, HG Othmer |
Journal of Mathematical Biology | 2004 |
Role of the tissue factor pathway in synovial inflammation
N Busso, C Morard, R Salvi, V P�clat, A So |
Arthritis & Rheumatism | 2003 |
Tissue factor and thrombin mediate myocardial ischemia-reperfusion injury
AJ Chong, TH Pohlman, CR Hampton, A Shimamoto, N Mackman, ED Verrier |
The Annals of Thoracic Surgery | 2003 |
Antithrombotics in thrombosis and cancer
SA Mousa |
Expert Review of Cardiovascular Therapy | 2003 |
Acquired resistance to activated protein C in breast cancer patients
MR Nijziel, R Oerle, M Christella, LG Thomassen, EC van Pampus, K Hamuly��k, G Tans, J Rosing |
British Journal of Haematology | 2003 |
Hemoglobin induces the production and release of matrix metalloproteinase-9 from human malignant cells
FA Siddiqui, TF Siddiqui, JL Francis |
Blood Coagulation & Fibrinolysis | 2003 |
Tumor angiogenesis of non-small cell lung cancer
N Shijubo, H Kojima, M Nagata, T Ohchi, A Suzuki, S Abe, N Sato |
Microscopy Research and Technique | 2003 |
Antimetastatic effect of tinzaparin, a low-molecular-weight heparin
A Amirkhosravi, SA Mousa, M Amaya, JL Francis |
Journal of Thrombosis and Haemostasis | 2003 |
Diverse role of LDL receptor-related protein in the clearance of proteases and in signaling
DK Strickland, S Ranganathan |
Journal of Thrombosis and Haemostasis | 2003 |
From Trousseau to targeted therapy: new insights and innovations in thrombosis and cancer
MN Levine, AY Lee, AK Kakkar |
Journal of Thrombosis and Haemostasis | 2003 |
Tissue specific expression and serum levels of human tissue factor in patients with urological cancer
Y Förster, A Meye, S Albrecht, M Kotzsch, S Füssel, MP Wirth, B Schwenzer |
Cancer Letters | 2003 |
An expanding role for antithrombotic therapy in cancer patients
AK Kakkar |
Cancer Treatment Reviews | 2003 |
Tissue factor expression and prognosis in patients with metastatic prostate cancer
T Akashi, Y Furuya, S Ohta, H Fuse |
Urology | 2003 |
Structural Insight into How An Anti-idiotypic Antibody Against D3H44 (Anti-tissue Factor Antibody) Restores Normal Coagulation
C Eigenbrot, YG Meng, R Krishnamurthy, MT Lipari, L Presta, B Devaux, T Wong, P Moran, S Bullens, D Kirchhofer |
Journal of Molecular Biology | 2003 |
Pharmacodynamic Properties of the Low Molecular Weight Heparin, Tinzaparin: Effect of Molecular Weight Distribution on Plasma Tissue Factor Pathway Inhibitor in Healthy Human Subjects
SA Mousa, J Bozarth, JS Barrett |
The Journal of Clinical Pharmacology | 2003 |
Increased levels of plasma tissue factor pathway inhibitor in patients with glioblastoma and intracerebral metastases
R Gerlach, T Scheuer, M Böhm, J Beck, A Woszczyk, A Raabe, I Scharrer, V Seifert |
Neurological Research | 2003 |
Tissue Factor, Thrombin, and Cancer
FR Rickles, S Patierno, PM Fernandez |
Chest | 2003 |
Synergistic effect of sphingosine 1-phosphate on thrombin-induced tissue factor expression in endothelial cells
H Takeya, EC Gabazza, S Aoki, H Ueno, K Suzuki |
Blood | 2003 |
Antiapoptotic effect of coagulation factor VIIa
BB Sorensen, LV Rao, D Tornehave, S Gammeltoft, LC Petersen |
Blood | 2003 |
Platelet–CD40 ligand interaction with melanoma cell and monocyte CD40 enhances cellular procoagulant activity
A Amirkhosravi, M Amaya, H Desai, JL Francis |
Blood Coagulation & Fibrinolysis | 2002 |
Evolving role of tissue factor and its pathway inhibitor
SN Doshi, JD Marmur |
Critical Care Medicine | 2002 |
Plasma fibrin D-dimer levels correlate with tumour volume, progression rate and survival in patients with metastatic breast cancer
LY Dirix, R Salgado, R Weytjens, C Colpaert, I Benoy, P Huget, P Dam, A Prové, J Lemmens, P Vermeulen |
British Journal of Cancer | 2002 |
Cancer and the prothrombotic state
GY Lip, BS Chin, AD Blann |
The Lancet Oncology | 2002 |
Tissue factor and angiogenesis in cancer
PM Fernandez, FR Rickles |
Current Opinion in Hematology | 2002 |
Hemoglobin binds melanoma cell tissue factor and enhances its procoagulant activity
FA Siddiqui, JL Francis |
Blood Coagulation & Fibrinolysis | 2002 |
Suppression of tissue factor expression, cofactor activity, and metastatic potential of murine melanoma cells by theN-terminal domain of adenovirus E1A 12S protein
C Voigtl�nder, A Rand, SL Liu, TJ Wilson, MR Pittelkow, MJ Getz, RJ Kelm |
Journal of Cellular Biochemistry | 2002 |
Expression of tissue factor and vascular endothelial growth factor is associated with angiogenesis in colorectal cancer
T Nakasaki, H Wada, C Shigemori, C Miki, EC Gabazza, T Nobori, S Nakamura, H Shiku |
American Journal of Hematology | 2002 |
The role of tumour-associated macrophages in tumour progression: implications for new anticancer therapies
L Bingle, NJ Brown, CE Lewis |
The Journal of Pathology | 2002 |
Production of tissue factor by pancreatic islet cells as a trigger of detrimental thrombotic reactions in clinical islet transplantation
L Moberg, H Johansson, A Lukinius, C Berne, A Foss, R Källen, Ø Østraat, K Salmela, A Tibell, G Tufveson, G Elgue, KN Ekdahl, O Korsgren, B Nilsson |
The Lancet | 2002 |
The hypercoagulable state of malignancy: pathogenesis and current debate
GJ Caine, PS Stonelake, GY Lip, ST Kehoe |
Neoplasia (New York, N.Y.) | 2002 |
Vaginal bleeding disturbances and implantable contraceptives
M Hickey, C d’Arcangues |
Contraception | 2002 |
Tissue factor expression and angiogenesis in human glioma
M Guan, J Jin, B Su, WW Liu, Y Lu |
Clinical Biochemistry | 2002 |
Two Patients with Arterial Thromboembolism among 311 Patients with Adenocarcinoma of the Pancreas
A Schattner, A Klepfish, A Shani, M Huszar |
The American Journal of the Medical Sciences | 2002 |
Tissue factor is the receptor for plasminogen type 1 on 1-LN human prostate cancer cells
M Gonzalez-Gronow, G Gawdi, SV Pizzo |
Blood | 2002 |
Induction of permeability across endothelial cell monolayers by tumor necrosis factor (TNF) occurs via a tissue factor–dependent mechanism: relationship between the procoagulant and permeability effects of TNF
J Friedl, M Puhlmann, DL Bartlett, SK Libutti, EN Turner, MF Gnant, HR Alexander |
Blood | 2002 |
Quantitative Reverse Transcription-PCR Measurement of Tissue Factor mRNA in Glioma
M Guan, B Su, Y Lu |
Molecular Biotechnology | 2002 |
The biology and tumour-related properties of monocyte tissue factor
BA Lwaleed, PS Bass, AJ Cooper |
The Journal of Pathology | 2001 |
The Role of the Hemostatic System in Tumor Growth, Metastasis, and Angiogenesis: Tissue factor is a Bifunctional Molecule Capable of Inducing Both Fibrin Deposition and Angiogenesis in Cancer
FR Rickles, M Shoji, K Abe |
International Journal of Hematology | 2001 |
The role of the coagulation system in tumour angiogenesis
GF Nash, DC Walsh, AK Kakkar |
The Lancet Oncology | 2001 |
Hemoglobin enhances tissue factor expression on human malignant cells
FA Siddiqui, A Amirkhosravi, M Amaya, T Meyer, J Biggerstaff, H Desai, JL Francis |
Blood Coagulation and Fibrinolysis | 2001 |
Tissue factor activity in human monocytes is regulated by plasma: implications for the high and low responder phenomenon
M Nijziel, R Oerle, C van, Veer, E Pampus, T Lindhout, K Hamulyak |
British Journal of Haematology | 2001 |
The hemostatic system and angiogenesis in malignancy
MZ Wojtukiewicz, E Sierko, P Klement, J Rak |
Neoplasia (New York, N.Y.) | 2001 |
Targeted Deletion of the Cytosolic Domain of Tissue Factor in Mice Does Not Affect Development
E Melis, L Moons, MD Mol, JM Herbert, N Mackman, D Collen, P Carmeliet, M Dewerchin |
Biochemical and Biophysical Research Communications | 2001 |
Role of GATA Motifs in Tissue Factor Pathway Inhibitor Gene Expression in Malignant Cells
MS Bajaj, DR Tyson, SA Steer, MN Kuppuswamy |
Thrombosis Research | 2001 |
Molecular Basis for the Relationship Between Thrombosis and Cancer
FR Rickles, A Falanga |
Thrombosis Research | 2001 |
The Hemostatic System and Angiogenesis in Malignancy
MZ Wojtukiewicz, E Sierko, P Klementt, J Rak |
Neoplasia (New York, N.Y.) | 2001 |
Purification and Properties of Human Melanoma Cell Tissue Factor
FA Siddiqui, A Amirkhosravi, M Amaya, H Desai, T Meyer, JL Francis |
Clinical and Applied Thrombosis/Hemostasis | 2001 |
Specificity, diversity, and convergence in VEGF and TNF-α signaling events leading to tissue factor up-regulation via EGR-1 in endothelial cells
D Mechtcheriakova, G Schabbauer, M Lucerna, M Clauss, RD Martin, BR Binder, E Hofer |
The FASEB Journal | 2001 |
Tissue factor–mediated endocytosis, recycling, and degradation of factor VIIa by a clathrin-independent mechanism not requiring the cytoplasmic domain of tissue factor
CB Hansen, C Pyke, LC Petersen, LV Rao |
Blood | 2001 |
Opposite Regulation of Tissue Factor Expression by Calcineurin in Monocytes and Endothelial Cells
H Hölschermann, C Rascher, C Oelschläger, G Stapfer, A Langenstein, A Staubitz, U Maus, H Tillmanns, H Bang, W Haberbosch |
Journal of immunology (Baltimore, Md. : 1950) | 2001 |
Angiopoietin‐1 negatively regulates expression and activity of tissue factor in endothelial cells
I Kim, JL Oh, YS Ryu, JN So, WC Sessa, K Walsh, GY Koh |
The FASEB Journal | 2001 |
Mouse embryogenesis requires the tissue factor extracellular domain but not the cytoplasmic domain
GC Parry, N Mackman |
Journal of Clinical Investigation | 2000 |
Vascular protease receptors: integrating haemostasis and endothelial cell functions
KT Preissner, PP Nawroth, SM Kanse |
The Journal of Pathology | 2000 |
Cytokine and intracellular signaling regulation of tissue factor expression in astrocytes
BD Klein, HS White, KS Callahan |
Neurochemistry International | 2000 |
Tissue factor expression in human colorectal carcinoma
S Seto, H Onodera, T Kaido, A Yoshikawa, S Ishigami, S Arii, M Imamura |
Cancer | 2000 |
Angiotensin II (AT1) Receptor Blockade Reduces Vascular Tissue Factor in Angiotensin II-Induced Cardiac Vasculopathy
DN Müller, EM Mervaala, R Dechend, A Fiebeler, JK Park, F Schmidt, J Theuer, V Breu, N Mackman, T Luther, W Schneider, D Gulba, D Ganten, H Haller, FC Luft |
The American Journal of Pathology | 2000 |
Functional implications of tissue factor localization to cell-cell contacts in myocardium
T Luther, DD Dittert, M Kotzsch, J Erlich, S Albrecht, N Mackman, M M�ller |
The Journal of Pathology | 2000 |
Increased D-dimer levels correlate with binding of activated protein C, but not tissue factor expression, on peripheral blood monocytes in cancer patients
MR Nijziel, R Oerle, EC Pampus, HC Vet, HF Hillen, K Hamuly�k |
American Journal of Hematology | 2000 |
Tissue factor expression in breast cancer tissues: its correlation with prognosis and plasma concentration
T Ueno, M Toi, M Koike, S Nakamura, T Tominaga |
British Journal of Cancer | 2000 |
Tissue factor, osteopontin, alphavbeta3 integrin expression in microvasculature of gliomas associated with vascular endothelial growth factor expression
S Takano, K Tsuboi, Y Tomono, Y Mitsui, T Nose |
British Journal of Cancer | 2000 |
Platelets
JN George |
The Lancet | 2000 |
Tissue factor expression and angiogenesisin human prostate carcinoma
SA Abdulkadir, GF Carvalhal, Z Kaleem, W Kisiel, PA Humphrey, WJ Catalona, J Milbrandt |
Human Pathology | 2000 |
Recombinant production of PIGF-1 and its activity in animal models
D Maglione, M Battisti, M Tucci |
Il Farmaco | 2000 |
Activation and Active Site Occupation Alter Conformation in the Region of the First Epidermal Growth Factor-like Domain of Human Factor VII
BJ Leonard, BJ Clarke, S Sridhara, R Kelley, FA Ofosu, MA Blajchman |
The Journal of biological chemistry | 2000 |
Factor VIIa/Tissue Factor-induced Signaling via Activation of Src-like Kinases, Phosphatidylinositol 3-Kinase, and Rac
HH Versteeg, I Hoedemaeker, SH Diks, JC Stam, M Spaargaren, PM van Henegouwen, SJ van Deventer, MP Peppelenbosch |
The Journal of biological chemistry | 2000 |
Tumor Necrosis Factor Employs a Protein-tyrosine Phosphatase to Inhibit Activation of KDR and Vascular Endothelial Cell Growth Factor-induced Endothelial Cell Proliferation
DQ Guo, LW Wu, JD Dunbar, ON Ozes, LD Mayo, KM Kessler, JA Gustin, MR Baerwald, EA Jaffe, RS Warren, DB Donner |
The Journal of biological chemistry | 2000 |
Vascular Endothelial Growth Factor KDR Receptor Signaling Potentiates Tumor Necrosis Factor-induced Tissue Factor Expression in Endothelial Cells
BQ Shen, DY Lee, KM Cortopassi, LA Damico, TF Zioncheck |
The Journal of biological chemistry | 2000 |
Binding of Factor VIIa to Tissue Factor on Keratinocytes Induces Gene Expression
E Camerer, E Gjernes, M Wiiger, S Pringle, H Prydz |
The Journal of biological chemistry | 2000 |
Basic Fibroblast Growth Factor Increases Tissue Factor Expression in Circulating Monocytes and in Vascular Wall
D Corseaux, T Meurice, I Six, L Rugeri, MD Ezekowitz, P Rouvier, R Bordet, C Bauters, B Jude |
Circulation | 2000 |
Effect of Bosentan on NF-κB, Inflammation, and Tissue Factor in Angiotensin II–Induced End-Organ Damage
DN Muller, EM Mervaala, F Schmidt, JK Park, R Dechend, E Genersch, V Breu, BM Löffler, D Ganten, W Schneider, H Haller, FC Luft |
Hypertension | 2000 |
Vascular Endothelial Growth Factor Production by Fibroblasts in Response to Factor VIIa Binding to Tissue Factor Involves Thrombin and Factor Xa
V Ollivier, J Chabbat, JM Herbert, J Hakim, D de Prost |
Arteriosclerosis, thrombosis, and vascular biology | 2000 |
Binding of factor VIIa to tissue factor on human fibroblasts leads to activation of phospholipase C and enhanced PDGF-BB–stimulated chemotaxis
A Siegbahn, M Johnell, C Rorsman, M Ezban, CH Heldin, L Rönnstrand |
Blood | 2000 |
Concentration-dependent dual effect of thrombin on impaired growth/apoptosis or mitogenesis in tumor cells
J Zain, YQ Huang, XS Feng, ML Nierodzik, JJ Li, S Karpatkin |
Blood | 2000 |
Vascular endothelial growth factor–stimulated endothelial cells promote adhesion and activation of platelets
HM Verheul, AS Jorna, K Hoekman, HJ Broxterman, MF Gebbink, HM Pinedo |
Blood | 2000 |
Actions of heparin that may affect the malignant process
H Engelberg |
Cancer | 1999 |
Factors Promoting Tumor Angiogenesis
ME Beckner |
Cancer Investigation | 1999 |
Expression of Thrombospondin-1 in Ischemia-Induced Retinal Neovascularization
K Suzuma, H Takagi, A Otani, H Oh, Y Honda |
The American Journal of Pathology | 1999 |
Early Induction of Angiogenetic Signals in Gliomas of GFAP-v-src Transgenic Mice
JP Theurillat, J Hainfellner, A Maddalena, J Weissenberger, A Aguzzi |
The American Journal of Pathology | 1999 |
Induction of differentiation in U-937 and NB4 cells is associated with inhibition of tissue factor production
T Tenno, F Öberg, K Nilsson, A Siegbahn |
European Journal of Haematology | 1999 |
Regulation of vascular endothelial growth factor production and angiogenesis by the cytoplasmic tail of tissue factor
K Abe, M Shoji, J Chen, A Bierhaus, I Danave, C Micko, K Casper, DL Dillehay, PP Nawroth, FR Rickles |
Proceedings of the National Academy of Sciences | 1999 |
Tissue factor is required for uterine hemostasis and maintenance of the placental labyrinth during gestation
J Erlich, GC Parry, C Fearns, M Muller, P Carmeliet, T Luther, N Mackman |
Proceedings of the National Academy of Sciences | 1999 |
Angiogenesis Induced by Tissue Factor in Vitro and in Vivo
T Watanabe, M Yasuda, T Yamamoto |
Thrombosis Research | 1999 |
Localization of Tissue Factor in Actin-Filament-Rich Membrane Areas of Epithelial Cells
M Müller, S Albrecht, F Gölfert, A Hofer, RH Funk, V Magdolen, C Flössel, T Luther |
Experimental Cell Research | 1999 |
Role of tissue factor expression on tumour cell invasion and growth of experimental pancreatic adenocarcinoma
AK Kakkar, V Chinswangwatanakul, NR Lemoine, S Tebbutt, RC Williamson |
The British journal of surgery | 1999 |
Expression of tissue factor in non-small-cell lung cancers and its relationship to metastasis
M Sawada, S Miyake, S Ohdama, O Matsubara, S Masuda, K Yakumaru, Y Yoshizawa |
British Journal of Cancer | 1999 |
State-of-the-Art Review : Chemotherapy and Thrombosis in Gynecologic Malignancy
GF Tempelhoff, K Pollow, D Schneider, L Heilmann |
Clinical and Applied Thrombosis/Hemostasis | 1999 |
Hämostaseologie
G Müller-Berghaus, B Pötzsch |
Hämostaseologie | 1999 |
Cardiovascular Specific Gene Expression
PA Doevendans, RS Reneman, M van Bilsen |
1999 | |
Antithrombotics
AC Uprichard, KP Gallagher |
1999 | |
Vascular Growth Factors and Angiogenesis
L Claesson-Welsh |
1999 | |
Vascular Endothelial Cell Growth Factor–Induced Tissue Factor Expression in Endothelial Cells Is Mediated by EGR-1
D Mechtcheriakova, A Wlachos, H Holzmüller, BR Binder, E Hofer |
Blood | 1999 |
Lipopolysaccharide Induction of Tissue Factor Expression in Rabbits
RN Moore, J Erlich, C Fearns, J Mathison, RJ Ulevitch, N Mackman |
Infection and immunity | 1999 |
Low levels of tissue factor are compatible with development and hemostasis in mice
GC Parry, JH Erlich, P Carmeliet, T Luther, N Mackman |
Journal of Clinical Investigation | 1998 |
Thrombomodulin modulates growth of tumor cells independent of its anticoagulant activity
Y Zhang, H Weiler-Guettler, J Chen, O Wilhelm, Y Deng, F Qiu, K Nakagawa, M Klevesath, S Wilhelm, H Böhrer, M Nakagawa, H Graeff, E Martin, DM Stern, RD Rosenberg, R Ziegler, PP Nawroth |
Journal of Clinical Investigation | 1998 |
Requirement for binding of catalytically active factor VIIa in tissue factor-dependent experimental metastasis
BM Mueller, W Ruf |
Journal of Clinical Investigation | 1998 |
Vascular development and disorders: Molecular analysis and pathogenic insights
P Carmeliet, D Collen |
Kidney International | 1998 |
Serum levels of tissue factor in colorectal cancer patients
C Shigemori |
International Journal of Clinical Oncology | 1998 |
Tissue-factor expression in human non-small-cell lung carcinoma measured by immunohistochemistry: Correlation between tissue factor and angiogenesis
R Koomägi, M Volm |
International Journal of Cancer | 1998 |
Molecules in focus Tissue factor
P Carmeliet, D Collen |
The International Journal of Biochemistry & Cell Biology | 1998 |
Tissue factor gene expression in the adipose tissues of obese mice
F Samad, M Pandey, DJ Loskutoff |
Proceedings of the National Academy of Sciences | 1998 |
Activation of coagulation and angiogenesis in cancer: immunohistochemical localization in situ of clotting proteins and vascular endothelial growth factor in human cancer
M Shoji, WW Hancock, K Abe, C Micko, KA Casper, RM Baine, JN Wilcox, I Danave, DL Dillehay, E Matthews, J Contrino, JH Morrissey, S Gordon, TS Edgington, B Kudryk, DL Kreutzer, FR Rickles |
The American Journal of Pathology | 1998 |
Tumor vascularity and hematogenous metastasis in experimental murine intraocular melanoma
HE Grossniklaus |
Transactions of the American Ophthalmological Society | 1998 |
A role for tissue factor in cell adhesion and migration mediated by interaction with actin-binding protein 280
I Ott, EG Fischer, Y Miyagi, BM Mueller, W Ruf |
The Journal of Cell Biology | 1998 |
Development and Disease in Proteinase-Deficient Mice
P Carmeliet, D Collen |
Thrombosis Research | 1998 |
Local Delivery of a Tissue Factor Antibody Reduces Early Leukocyte Infiltration but Fails to Limit Intimal Hyperplasia in Experimental Vein Grafts1
BH Annex, MG Davies, GJ Fulton, TT Huynh, KM Channon, MD Ezekowitz, PO Hagen |
Journal of Surgical Research | 1998 |
Signal Transduction via the Mitogen-activated Protein Kinase Pathway Induced by Binding of Coagulation Factor VIIa to Tissue Factor
LK Poulsen, N Jacobsen, BB Sørensen, NC Bergenhem, JD Kelly, DC Foster, O Thastrup, M Ezban, LC Petersen |
The Journal of biological chemistry | 1998 |
Hormoneller Zyklus, Schwangerschaft und Thrombose
V Hach-Wunderle, E Loch |
1998 | |
Role of Tissue Factor in Adhesion of Mononuclear Phagocytes to and Trafficking Through Endothelium In Vitro
GJ Randolph, T Luther, S Albrecht, V Magdolen, WA Muller |
Blood | 1998 |
Tissue Factor-Dependent Vascular Endothelial Growth Factor Production by Human Fibroblasts in Response to Activated Factor VII
V Ollivier, S Bentolila, J Chabbat, J Hakim, D de Prost |
Blood | 1998 |
Tissue Factor Regulates Plasminogen Binding and Activation
Z Fan, PJ Larson, J Bognacki, PN Raghunath, JE Tomaszewski, A Kuo, G Canziani, I Chaiken, DB Cines, AA Higazi |
Blood | 1998 |
Low-molecular-weight heparin in the management of Tyrousseau's syndrome
D Walsh-McMonagle, D Green |
Cancer | 1997 |
Inhibition of malignant angiogenesis
AP Jekunen, KJ Kairemo |
Cancer Treatment Reviews | 1997 |
Angiogenesis: new aspects relating to its initiation and control
K Norrby |
APMIS | 1997 |
Insights in Vessel Development and Vascular Disorders Using Targeted Inactivation and Transfer of Vascular Endothelial Growth Factor, the Tissue Factor Receptor, and the Plasminogen System
P Carmeliet, L Moons, M Dewerchin, N Mackman, T Luther, G Breier, V Ploplis, M Müller, A Nagy, E Plow, R Gerard, T Edgington, W Risau, D Collen |
Annals of the New York Academy of Sciences | 1997 |
Analysis of tissue factor and tissue factor pathway inhibitor expression in human colorectal carcinoma cell lines and metastatic sublines to the liver
H Kataoka, H Uchino, Y Asada, K Hatakeyama, K Nabeshima, A Sumiyoshi, M Koono |
International Journal of Cancer | 1997 |
Effect of tissue factor deficiency on mouse and tumor development
JR Toomey, KE Kratzer, NM Lasky, GJ Broze |
Proceedings of the National Academy of Sciences | 1997 |
Tissue factor initiates glomerular fibrin deposition and promotes major histocompatibility complex class II expression in crescentic glomerulonephritis
JH Erlich, SR Holdsworth, PG Tipping |
The American Journal of Pathology | 1997 |
Binding of factor VIIa to tissue factor induces alterations in gene expression in human fibroblast cells: up-regulation of poly(A) polymerase
UR Pendurthi, D Alok, LV Rao |
Proceedings of the National Academy of Sciences | 1997 |
Insights from gene-inactivation studies of the coagulation and plasminogen
P Carmeliet |
Fibrinolysis and Proteolysis | 1997 |
Binding of factor VIIa to tissue factor induces alterations in gene expression in human fibroblast cells: Up-regulation of poly(A) polymerase
UR Pendurthi, D Alok, LV Rao |
Proceedings of the National Academy of Sciences | 1997 |
Molecular analysis of blood vessel formation and disease
N Ferrara |
The American journal of physiology | 1997 |
Molecular and Structural Advances in Tissue Factor-Dependent Coagulation
D Kirchhofer, DW Banner |
Trends in Cardiovascular Medicine | 1997 |
Molecular Mechanisms Linking Thrombosis and Angiogenesis in Cancer
M Shoji, K Abe, PP Nawroth, FR Rickles |
Trends in Cardiovascular Medicine | 1997 |
Genetic Analysis of Blood Vessel Formation
P Carmeliet, D Collen |
Trends in Cardiovascular Medicine | 1997 |
Abnormal angiogenesis and responses to glucose and oxygen deprivation in mice lacking the protein ARNT
E Maltepe, JV Schmidt, D Baunoch, CA Bradfield, MC Simon |
Nature | 1997 |
Advanced Glycation End Product (AGE)–Mediated Induction of Tissue Factor in Cultured Endothelial Cells Is Dependent on RAGE
A Bierhaus, T Illmer, M Kasper, T Luther, P Quehenberger, H Tritschler, P Wahl, R Ziegler, M Müller, PP Nawroth |
Circulation | 1997 |
Modulation of Tissue Factor Protein Expression in Experimental Venous Bypass Grafts
KM Channon, GJ Fulton, MG Davies, KG Peters, MD Ezekowitz, PO Hagen, BH Annex |
Arteriosclerosis, thrombosis, and vascular biology | 1997 |
Target effector role of vascular endothelium in the inflammatory response: insights from the clinical trial of anti-TNF alpha antibody in rheumatoid arthritis
E Paleolog |
Molecular Pathology | 1997 |
Textbook of Coronary Thrombosis and Thrombolysis
RC Becker |
1997 | |
Borna Disease Virus and the Brain
D GonzalezDunia, C Sauder, JC de la Torre |
Brain Research Bulletin | 1997 |
Intravenous somatic gene transfer with antisense tissue factor restores blood flow by reducing tumor necrosis factor-induced tissue factor expression and fibrin deposition in mouse meth-A sarcoma
Y Zhang, Y Deng, T Wendt, B Liliensiek, A Bierhaus, J Greten, W He, B Chen, V Hach-Wunderle, R Waldherr, R Ziegler, D Männel, DM Stern, PP Nawroth |
Journal of Clinical Investigation | 1996 |
In situ detection of tissue factor in vascular endothelial cells: Correlation with the malignant phenotype of human breast disease
J Contrino, G Hair, DL Kreutzer, FR Rickles |
Nature Medicine | 1996 |
Identification of Hypoxically Inducible mRNAs in HeLa Cells Using Differential-Display PCR
JF O'rourke, CW Pugh, SM Bartlett, PJ Ratcliffe |
European Journal of Biochemistry | 1996 |
Initiation of blood coagulation: the tissue factor/factor VIIa complex
D Kirchhofer, Y Nemerson |
Current Opinion in Biotechnology | 1996 |
Expression of tissue factor correlates with grade of malignancy in human glioma
K Hamada, J Kuratsu, Y Saitoh, H Takeshima, T Nishi, Y Ushio |
Cancer | 1996 |
Tissue factor expression in normal and abnormal mammary gland
T Luther, C Flössel, S Albrecht, M Kotzsch, M Müller |
Nature Medicine | 1996 |
Reply to “Tissue factor expression in normal and abnormal mammary gland”
FR Rickles, J Contrino, DL Kreutzer |
Nature Medicine | 1996 |
Expression of tissue factor is increased in astrocytes within the central nervous system during persistent infection with borna disease virus
D Gonzalez-Dunia, M Eddleston, N Mackman, K Carbone, JC de la Torre |
Journal of virology | 1996 |
Tissue factor expression during human and mouse development
T Luther, C Flössel, N Mackman, A Bierhaus, M Kasper, S Albrecht, EH Sage, L Iruela-Arispe, H Grossmann, A Ströhlein, Y Zhang, PP Nawroth, P Carmeliet, DJ Loskutoff, M Müller |
The American Journal of Pathology | 1996 |
Cell biology of tissue factor, the principal initiator of blood coagulation
E Camerer, AB Kolstø, H Prydz |
Thrombosis Research | 1996 |
Tissue factor expression in human leukemic cells
GA Hair, S Padula, R Zeff, M Schmeizl, J Contrino, DL Kreutzer, P Moerloose, AW Boyd, I Stanley, AW Burgess, FR Rickles |
Leukemia Research | 1996 |
Targeted gene manipulation and transfer of the plasminogen and coagulation systems in mice
P Carmeliet, D Collen |
Fibrinolysis | 1996 |
Role of tissue factor in embryonic blood vessel development
P Carmeliet, N Mackman, L Moons, T Luther, P Gressens, IV Vlaenderen, H Demunck, M Kasper, G Breier, P Evrard, M Müller, W Risau, T Edgington, D Collen |
Nature | 1996 |
The vascular endothelial growth factor receptor Flt-1 mediates biological activities. Implications for a functional role of placenta growth factor in monocyte activation and chemotaxis
M Clauss, H Weich, G Breier, U Knies, W Röckl, J Waltenberger, W Risau |
The Journal of biological chemistry | 1996 |
Attempts to Understand Metastasis Formation II
U Günthert, W Birchmeier |
1996 | |
Malignome und Hämostase
E Spanuth |
1996 | |
Tissue factor promotes melanoma metastasis by a pathway independent of blood coagulation
ME Bromberg, WH Konigsberg, JF Madison, A Pawashe, A Garen |
Proceedings of the National Academy of Sciences | 1995 |
Regulation of the extrinsic pathway system in health and disease: The role of factor VIIa and tissue factor pathway inhibitor
LC Petersen, S Valentin, U Hedner |
Thrombosis Research | 1995 |
Mechanism of the Tumor Necrosis Factor α-mediated Induction of Endothelial Tissue Factor
A Bierhaus, Y Zhang, Y Deng, N Mackman, P Quehenberger, M Haase, T Luther, M Müller, H Böhrer, J Greten, E Martin, PA Baeuerle, R Waldherr, W Kisiel, R Ziegler, DM Stern, PP Nawroth |
The Journal of biological chemistry | 1995 |
Growth Factor Therapies for Vascular Injury and Ischemia
W Casscells |
Circulation | 1995 |
Encyclopedic Reference of Vascular Biology & Pathology
A Bikfalvi |
1990 | |
Thrombin
JW Fenton |
Annals of the New York Academy of Sciences | 1986 |