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S Ishibashi, … , R E Hammer, J Herz
Published August 1, 1993
Citation Information: J Clin Invest. 1993;92(2):883-893. https://doi.org/10.1172/JCI116663.
Citation Information: J Clin Invest. 1993;92(2):883-893. https://doi.org/10.1172/JCI116663.
Abstract
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S Ishibashi, M S Brown, J L Goldstein, R D Gerard, R E Hammer, J Herz
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Citations to this article (1551)
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|
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2021 | |
|
Enterohepatic Transcription Factor CREB3L3 Protects Atherosclerosis via SREBP Competitive Inhibition
Y Nakagawa, Y Wang, S Han, K Okuda, A Oishi, Y Yagishita, K Kumagai, H Ohno, Y Osaki, Y Mizunoe, M Araki, Y Murayama, H Iwasaki, M Konishi, N Itoh, T Matsuzaka, H Sone, N Yamada, H Shimano |
CMGH Cellular and Molecular Gastroenterology and Hepatology | 2021 |
|
The changing landscape of the vulnerable plaque: a call for fine-tuning of preclinical models
MF Buono, L Slenders, M Wesseling, RJ Hartman, C Monaco, HM den Ruijter, G Pasterkamp, M Mokry |
Vascular Pharmacology | 2021 |
|
SNCs meet SMCs in the atherosclerotic plaque
I Kabir, DM Greif |
2021 | |
|
Adropin transgenesis improves recognition memory in diet-induced obese LDLR-deficient C57BL/6J mice
S Ghoshal, S Banerjee, J Zhang, ML Niehoff, SA Farr, AA Butler |
Peptides | 2021 |
|
Comparative proteomics elucidates the dynamics of ovarian development in the Chinese mitten crab Eriocheir sinensis
Q Feng, M Liu, Y Cheng, X Wu |
Comparative biochemistry and physiology. Part D, Genomics & proteomics | 2021 |
|
Divergent low-density lipoprotein receptor (LDLR) linked to low VSV G-dependent viral infectivity and unique serum lipid profile in zebra finches
TA Velho, PV Lovell, SR Friedrich, CR Olson, J Miles, PA Mueller, H Tavori, S Fazio, C Lois, CV Mello |
Proceedings of the National Academy of Sciences | 2021 |
|
Inhibition of Extracellular Cathepsin D Reduces Hepatic Lipid Accumulation and Leads to Mild Changes in Inflammationin NASH Mice
T Yadati, T Houben, A Bitorina, Y Oligschlaeger, MJ Gijbels, R Mohren, D Lütjohann, P Khurana, S Goyal, A Kulkarni, J Theys, B Cillero-, R Shiri-Sverdlov |
Frontiers in immunology | 2021 |
|
Dietary Neu5Ac Intervention Protects Against Atherosclerosis Associated With Human-Like Neu5Gc Loss—Brief Report
K Kawanishi, JK Coker, KV Grunddal, C Dhar, J Hsiao, K Zengler, N Varki, A Varki, PL Gordts |
Arteriosclerosis, thrombosis, and vascular biology | 2021 |
|
Cholesterol metabolism is decreased in patients with diminished ovarian reserve
X Yang, Z Zhao, Q Fan, H Li, L Zhao, C Liu, X Liang |
Reproductive BioMedicine Online | 2021 |
|
SNCs meet SMCs in the atherosclerotic plaque.
Kabir I, Greif DM |
2021 | |
|
Gestational oxidative stress protects against adult obesity and insulin resistance
LG Dimova, S Battista, T Plösch, RA Kampen, F Liu, RN Verkaik-Schakel, D Pratico, HJ Verkade, UJ Tietge |
Redox Biology | 2020 |
|
Diabetic atherosclerosis: is there a role for the hypoxia-inducible factors?
D Pirri, M Fragiadaki, PC Evans |
Bioscience Reports | 2020 |
|
Characterization of a mouse model to study the relationship between apical periodontitis and atherosclerosis
Y BerlinBroner, M Alexiou, L Levin, M Febbraio |
International Endodontic Journal | 2020 |
|
Cow's milk polar lipids reduce atherogenic lipoprotein cholesterol, modulate gut microbiota and attenuate atherosclerosis development in LDL-receptor knockout mice fed a Western-type diet
CL Millar, C Jiang, GH Norris, C Garcia, S Seibel, L Anto, JY Lee, CN Blesso |
The Journal of Nutritional Biochemistry | 2020 |
|
A chalcone derivative, 1m‐6, exhibits atheroprotective effects by increasing cholesterol efflux and reducing inflammation‐induced endothelial dysfunction
LW Chen, MC Tsai, CY Chern, TP Tsao, FY Lin, SJ Chen, PF Tsui, YW Liu, HJ Lu, WL Wu, WS Lin, CS Tsai, CS Lin |
British Journal of Pharmacology | 2020 |
|
PTH/PTHrP Receptor Signaling Restricts Arterial Fibrosis in Diabetic LDLR −/− Mice by Inhibiting Myocardin-Related Transcription Factor Relays
A Behrmann, D Zhong, L Li, SL Cheng, M Mead, B Ramachandran, P Sabaeifard, M Goodarzi, A Lemoff, HM Kronenberg, DA Towler |
Circulation research | 2020 |
|
Mouse models of atherosclerosis and their suitability for the study of myocardial infarction
P Golforoush, DM Yellon, SM Davidson |
Basic Research in Cardiology | 2020 |
|
Hyperalphalipoproteinemic scavenger receptor BI knockout mice exhibit a disrupted epidermal lipid barrier
RM Cardoso, E Creemers, S Absalah, M Hoekstra, GS Gooris, JA Bouwstra, MV Eck |
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids | 2020 |
|
Sex as a Biological Variable in Atherosclerosis
JJ Man, JA Beckman, IZ Jaffe |
Circulation research | 2020 |
|
Progeria, atherosclerosis and clonal hematopoiesis: links and future perspectives
C Mozzini |
Mechanisms of Ageing and Development | 2020 |
|
Autoantibody Responses to Apolipoprotein A-I Are Not Diet- or Sex-Linked in C57BL/6 Mice
MG Pitts, D Nardo, CM Isom, VJ Venditto |
ImmunoHorizons | 2020 |
|
Germ-free housing conditions do not affect aortic root and aortic arch lesion size of late atherosclerotic low-density lipoprotein receptor-deficient mice
K Kiouptsi, G Pontarollo, H Todorov, J Braun, S Jäckel, T Koeck, F Bayer, C Karwot, A Karpi, S Gerber, Y Jansen, P Wild, W Ruf, A Daiber, EV Vorst, C Weber, Y Döring, C Reinhardt |
Gut microbes | 2020 |
|
Inhibition of PCSK9 potentiates immune checkpoint therapy for cancer
X Liu, X Bao, M Hu, H Chang, M Jiao, J Cheng, L Xie, Q Huang, F Li, CY Li |
Nature | 2020 |
|
Glucocorticoids are active players and therapeutic targets in atherosclerotic cardiovascular disease
RJ van der Sluis, M Hoekstra |
Molecular and Cellular Endocrinology | 2020 |
|
Art of Making Artificial Liver: Depicting Human Liver Biology and Diseases in Mice
G Sugahara, Y Ishida, J Sun, C Tateno, T Saito |
Seminars in liver disease | 2020 |
|
Dare to Compare. Development of Atherosclerotic Lesions in Human, Mouse, and Zebrafish
VL Vedder, Z Aherrahrou, J Erdmann |
Frontiers in Cardiovascular Medicine | 2020 |
|
Preclinical models of disease and multimorbidity with focus upon cardiovascular disease and dementia
O Shabir, TA Moll, MM Matuszyk, B Eyre, MD Dake, J Berwick, SE Francis |
Mechanisms of Ageing and Development | 2020 |
|
Hsa-miRNA-23a-3p promotes atherogenesis in a novel mouse model of atherosclerosis
J Guo, H Mei, Z Sheng, Q Meng, MM Véniant, H Yin |
Journal of lipid research | 2020 |
|
Heterogeneity in clone dynamics within and adjacent to intestinal tumours identified by Dre-mediated lineage tracing
AS Thorsen, D Khamis, R Kemp, M Colombé, FC Lourenço, E Morrissey, D Winton |
Disease models & mechanisms | 2020 |
|
Hyperhomocysteinemia and dyslipidemia in point mutation G307S of cystathionine β-synthase-deficient rabbit generated using CRISPR/Cas9
T Zhang, R Lu, Y Chen, Y Yuan, S Song, K Yan, Y Zha, W Zhuang, Y Cheng, J Liang |
Lipids in Health and Disease | 2020 |
|
β-Carotene conversion to vitamin A delays atherosclerosis progression by decreasing hepatic lipid secretion in mice
F Zhou, X Wu, I Pinos, BM Abraham, TJ Barrett, J von Lintig, EA Fisher, J Amengual |
Journal of lipid research | 2020 |
|
The History of the WHHL Rabbit, an Animal Model of Familial Hypercholesterolemia (II) - Contribution to the Development and Validation of the Therapeutics for Hypercholesterolemia and Atherosclerosis -
M Shiomi |
Journal of Atherosclerosis and Thrombosis | 2020 |
|
Activation of estrogen receptor α (ERα) is required for Alisol B23-acetate to prevent post-menopausal atherosclerosis and reduced lipid accumulation
Q Chen, Y Chao, W Zhang, Y Zhang, Y Bi, Y Fu, D Cai, Q Meng, Y Li, H Bian |
Life Sciences | 2020 |
|
Formation of atherosclerotic lesions is independent of eosinophils in male mice
K Hofheinz, F Seibert, JA Ackermann, B Dietel, M Tauchi, M Oszvar-Kozma, H Kühn, G Schett, CJ Binder, G Krönke |
Atherosclerosis | 2020 |
|
Deep Phenotyping by Mass Cytometry and Single Cell RNA-Sequencing Reveals LYN Regulated Signaling Profiles Underlying Monocyte Subset Heterogeneity and Lifespan
ME Roberts, M Barvalia, JA Silva, RA Cederberg, W Chu, A Wong, D Tai, S Chen, I Matos, J Priatel, PR cullis, K Harder |
Circulation research | 2020 |
|
Small rodent models of atherosclerosis
Y Zhao, H Qu, Y Wang, W Xiao, Y Zhang, D Shi |
Biomedicine & pharmacotherapy = Biomédecine & pharmacothérapie | 2020 |
|
Cardiometabolic Syndrome: An Update on Available Mouse Models
D Aravani, E Kassi, A Chatzigeorgiou, S Vakrou |
Thrombosis and Haemostasis | 2020 |
|
Hyperlipidemic Rabbit Models for Anti-Atherosclerotic Drug Development
M Niimi, Y Chen, H Yan, Y Wang, T Koike, J Fan |
Applied Sciences | 2020 |
|
Sex-Dependent Molecular Mechanisms of Lipotoxic Injury in Brain Microvasculature: Implications for Dementia
S Nuthikattu, D Milenkovic, JC Rutledge, AC Villablanca |
International journal of molecular sciences | 2020 |
|
Red wine consumption mitigates the cognitive impairments in low-density lipoprotein receptor knockout (LDLr −/− ) mice
GC Paula, J de Oliveira, DF Engel, SC Lopes, EL Moreira, CP Figueiredo, RD Prediger, AF de Bem |
Nutritional Neuroscience | 2020 |
|
Lactobacillus reuteri attenuates cardiac injury without lowering cholesterol in low-density lipoprotein receptor-deficient mice fed standard chow
MP Koppinger, MA Lopez-Pier, R Skaria, PR Harris, JP Konhilas |
American journal of physiology. Heart and circulatory physiology | 2020 |
|
Trimethylamine N-oxide and the reverse cholesterol transport in cardiovascular disease: a cross-sectional study
L Bordoni, JJ Samulak, AK Sawicka, I Pelikant-Malecka, A Radulska, L Lewicki, L Kalinowski, R Gabbianelli, RA Olek |
Scientific Reports | 2020 |
|
Hyperlipidemia
J Stewart, T McCallin, J Martinez, S Chacko, S Yusuf |
Pediatrics in Review | 2020 |
|
Role of the adaptive immune system in atherosclerosis
K Ley |
Biochemical Society Transactions | 2020 |
|
Artificial switching of the metabolic processing pathway of an etiologic factor, β2-microglobulin, by a “navigator” molecule
Y Kambe, K Koyashiki, Y Hirano, M Harada-Shiba, T Yamaoka |
Journal of Controlled Release | 2020 |
|
High Cholesterol Diet Exacerbates Blood-Brain Barrier Disruption in LDLr–/– Mice: Impact on Cognitive Function
J de Oliveira, DF Engel, GC de Paula, DB dos Santos, JB Lopes, M Farina, EL Moreira, AF de Bem |
Journal of Alzheimer's disease : JAD | 2020 |
|
PCSK9Qβ-003 Vaccine Attenuates Atherosclerosis in Apolipoprotein E-Deficient Mice
D Wu, Y Pan, S Yang, C Li, Y Zhou, Y Wang, X Chen, Z Zhou, Y Liao, Z Qiu |
Cardiovascular Drugs and Therapy | 2020 |
|
Mild hyperlipidemia in mice aggravates platelet responsiveness in thrombus formation and exploration of platelet proteome and lipidome
JP van Geffen, F Swieringa, K van Kuijk, BM Tullemans, FA Solari, B Peng, KJ Clemetson, RW Farndale, LJ Dubois, A Sickmann, RP Zahedi, R Ahrends, EA Biessen, JC Sluimer, JW Heemskerk, MJ Kuijpers |
Scientific Reports | 2020 |
|
Reply to Soulillou et al.: Difficulties in extrapolating from animal models exemplify unusual human atherosclerosis susceptibility and mechanisms via CMAH loss
K Kawanishi, C Dhar, A Varki, PL Gordts |
Proceedings of the National Academy of Sciences | 2020 |
|
Pressure overload leads to coronary plaque formation, progression and myocardial events in ApoE-/- mice
Alice Marino, Yi Zhang, Luisa Rubinelli, Maria Antonietta Riemma, James E. Ip, Annarita Di Lorenzo |
JCI Insight | 2019 |
|
System biology identifies cytosolic PLA2 as a target in vascular calcification treatment
Joost Peter Schanstra, Trang T. D. Luong, Manousos Makridakis, Sophie Van Linthout, Vasiliki Lygirou, Agnieszka Latosinska, ioana alesutan, Beate Boehme, Nadeshda Schelski, Dirk von Lewinski, William Mullen, Stuart A Nicklin, Christian Delles, Guylène Feuillet, Denis colette, Florian Lang, Burkert Pieske, Jean-Loup Bascands, Harald Mischak, Jean-Sebastien Saulnier-Blache, jakob voelkl, Antonia Vlahou, Julie Klein |
JCI Insight | 2019 |
|
The hepatic WASH complex is required for efficient plasma LDL and HDL cholesterol clearance
Melinde Wijers, Paolo Zanoni, Nalan Liv, Dyonne Y. Vos, Michelle Y Jäckstein, Marieke Smit, Sanne Wilbrink, Justina C. Wolters, Ydwine Y.T. van der Veen, N.C.A. Huijkman, Daphne Dekker, Niels J Kloosterhuis, Theo H. van Dijk, Daniel Billadeau, Folkert Kuipers, Judith Klumperman, Arnold von Eckardstein, Jan Albert Kuivenhoven, Bart van de Sluis |
JCI Insight | 2019 |
|
Lowering circulating Apolipoprotein E levels improves aged bone fracture healing
Rong Huang, Xiaohua Zong, Puviindran Nadesan, Janet Huebner, Virginia Kraus, James White, Phillip White, Gurpreet Baht |
JCI Insight | 2019 |
|
Human species-specific loss of CMP- N -acetylneuraminic acid hydroxylase enhances atherosclerosis via intrinsic and extrinsic mechanisms
K Kawanishi, C Dhar, R Do, N Varki, PL Gordts, A Varki |
Proceedings of the National Academy of Sciences | 2019 |
|
The Microbiota Promotes Arterial Thrombosis in Low-Density Lipoprotein Receptor-Deficient Mice
K Kiouptsi, S Jäckel, G Pontarollo, A Grill, MJ Kuijpers, E Wilms, C Weber, F Sommer, M Nagy, C Neideck, Y Jansen, S Ascher, H Formes, C Karwot, F Bayer, B Kollar, S Subramaniam, M Molitor, P Wenzel, P Rosenstiel, H Todorov, S Gerber, U Walter, K Jurk, JW Heemskerk, EP van der Vorst, Y Döring, C Reinhardt, F Rey, NA Moran |
mBio | 2019 |
|
Microarray and proteome array in an atherosclerosis mouse model for identification of biomarkers in whole blood
SY Gwon, HM Lee, KJ Rhee, HJ Sung |
International journal of medical sciences | 2019 |
|
Immunity and Inflammation in Atherosclerosis
D Wolf, K Ley |
Circulation research | 2019 |
|
Immunität und Entzündung bei Arteriosklerose
D Wolf, K Ley |
Herz | 2019 |
|
Lipoprotein receptor signalling in atherosclerosis
C Mineo |
Cardiovascular Research | 2019 |
|
Macrophage NCOR1 protects from atherosclerosis by repressing a pro-atherogenic PPARγ signature
S Oppi, S Nusser-Stein, P Blyszczuk, X Wang, A Jomard, V Marzolla, K Yang, S Velagapudi, LJ Ward, , MA Geiger, AT Guillaumon, A Othman, T Hornemann, Z Rancic, D Ryu, MH Oosterveer, E Osto, TF Lüscher, S Stein |
European Heart Journal | 2019 |
|
Low Density Receptor-Related Protein 1 Interactions With the Extracellular Matrix: More Than Meets the Eye
EE Bres, A Faissner |
Frontiers in Cell and Developmental Biology | 2019 |
|
Peripheral versus central nervous system APOE in Alzheimer’s disease: Interplay across the blood-brain barrier
D Chernick, S Ortiz-Valle, A Jeong, W Qu, L Li |
Neuroscience Letters | 2019 |
|
The Roles of Cholesterol and Its Metabolites in Normal and Malignant Hematopoiesis
H Oguro |
Frontiers in Endocrinology | 2019 |
|
The Effects of Cholesterol Metabolism on Follicular Development and Ovarian Function
Q Huang, Y Liu, Z Yang, Y Xie, Z Mo |
Current molecular medicine | 2019 |
|
Impaired adult hippocampal neurogenesis in a mouse model of familial hypercholesterolemia: A role for the LDL receptor and cholesterol metabolism in adult neural precursor cells
DF Engel, AN Grzyb, J de Oliveira, A Pötzsch, TL Walker, PS Brocardo, G Kempermann, AF de Bem |
Molecular Metabolism | 2019 |
|
FAK and Pyk2 activity promote TNF-α and IL-1β-mediated pro-inflammatory gene expression and vascular inflammation
JM Murphy, K Jeong, YA Rodriguez, JH Kim, EY Ahn, ST Lim |
Scientific Reports | 2019 |
|
Increased Reactive Oxygen Species Generation Contributes to the Atherogenic Activity of the B2 Bradykinin Receptor
A Perhal, S Wolf, YF Jamous, A Langer, JA Alla, U Quitterer |
Frontiers in Medicine | 2019 |
|
Vascular smooth muscle cells in atherosclerosis
GL Basatemur, HF Jørgensen, MC Clarke, MR Bennett, Z Mallat |
Nature Reviews Cardiology | 2019 |
|
Apoproteins E, A-I, and SAA in Macrophage Pathobiology Related to Atherogenesis
GS Getz, CA Reardon |
Frontiers in pharmacology | 2019 |
|
Vascular smooth muscle cell loss underpins the accelerated atherosclerosis in Hutchinson-Gilford progeria syndrome
MR Hamczyk, V Andrés |
Nucleus | 2019 |
|
Lack of hepatic apoE does not influence early Aβ deposition: observations from a new APOE knock-in model
TP Huynh, C Wang, AC Tran, GT Tabor, TE Mahan, CM Francis, MB Finn, R Spellman, M Manis, RE Tanzi, JD Ulrich, DM Holtzman |
Molecular Neurodegeneration | 2019 |
|
A review of gene- and cell-based therapies for familial hypercholesterolemia
S Hajighasemi, AM Gorabi, V Bianconi, M Pirro, M Banach, HA Tafti, Ž Reiner, A Sahebkar |
Pharmacological research : the official journal of the Italian Pharmacological Society | 2019 |
|
Effects of Pharmacological Thermogenic Adipocyte Activation on Metabolism and Atherosclerotic Plaque Regression
A Worthmann, C Schlein, J Berbée, P Rensen, J Heeren, A Bartelt |
Nutrients | 2019 |
|
An update on the tools for creating transgenic animal models of human diseases – focus on atherosclerosis
AS Volobueva, AN Orekhov, AV Deykin |
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas / Sociedade Brasileira de Biofisica ... [et al.] | 2019 |
|
Cytokine Circuits in Cardiovascular Disease
JW Williams, L Huang, GJ Randolph |
Immunity | 2019 |
|
Lipid Droplet Accumulation in Human Pancreatic Islets is Dependent Upon Both Donor Age and Health
X Tong, C Dai, JT Walker, GG Nair, A Kennedy, RM Carr, M Hebrok, AC Powers, R Stein |
Diabetes | 2019 |
|
Mouse Models for Atherosclerosis Research—Which Is My Line?
S Oppi, TF Lüscher, S Stein |
Frontiers in Cardiovascular Medicine | 2019 |
|
Knockout rat models mimicking human atherosclerosis created by Cpf1-mediated gene targeting
JG Lee, CH Ha, B Yoon, SA Cheong, G Kim, DJ Lee, DC Woo, YH Kim, SY Nam, S Lee, YH Sung, IJ Baek |
Scientific Reports | 2019 |
|
Mast Cells as Potential Accelerators of Human Atherosclerosis—From Early to Late Lesions
PT Kovanen |
International journal of molecular sciences | 2019 |
|
CKIP-1 limits foam cell formation and inhibits atherosclerosis by promoting degradation of Oct-1 by REGγ
J Fan, L Liu, Q Liu, Y Cui, B Yao, M Zhang, Y Gao, Y Fu, H Dai, J Pan, Y Qiu, CH Liu, F He, Y Wang, L Zhang |
Nature Communications | 2019 |
|
Identification of amino acid residues in the ligand binding repeats of LDL receptor important for PCSK9 binding
S Deng, A Alabi, H Gu, A Adijiang, S Qin, D Zhang |
Journal of lipid research | 2019 |
|
Cholesterol transport system: An integrated cholesterol transport model involved in atherosclerosis
XH Yu, DW Zhang, , CK Tang |
Progress in Lipid Research | 2019 |
|
Short-term and long-term effects of a loading dose of atorvastatin before percutaneous coronary intervention on major adverse cardiovascular events in patients with acute coronary syndrome: a meta-analysis of 13 randomized controlled trials
Z Ye, H Lu, Q Su, M Long, L Li |
European Heart Journal | 2019 |
|
Resveratrol - Adding Life to Years, Not Adding Years to Life
FA Badria |
2019 | |
|
Adaptive Strategies of the Candidate Probiotic E. coli Nissle in the Mammalian Gut
N Crook, A Ferreiro, AJ Gasparrini, MW Pesesky, MK Gibson, B Wang, X Sun, Z Condiotte, S Dobrowolski, D Peterson, G Dantas |
Cell Host & Microbe | 2019 |
|
Simultaneous LC/MS/MS quantification of eight apolipoproteins in normal and hypercholesterolemic mouse plasma
R Wagner, J Dittrich, J Thiery, U Ceglarek, R Burkhardt |
Journal of lipid research | 2019 |
|
Intermittent Hypoxia and Hypercapnia Reproducibly Change the Gut Microbiome and Metabolome across Rodent Model Systems
A Tripathi, ZZ Xu, J Xue, O Poulsen, A Gonzalez, G Humphrey, MJ Meehan, AV Melnik, G Ackermann, D Zhou, A Malhotra, GG Haddad, PC Dorrestein, R Knight, TM Flynn |
mSystems | 2019 |
|
Peptide Amphiphile Supramolecular Nanostructures as a Targeted Therapy for Atherosclerosis
NA Mansukhani, EB Peters, MM So, MS Albaghdadi, Z Wang, MR Karver, TD Clemons, JP Laux, ND Tsihlis, SI Stupp, MR Kibbe |
Macromolecular Bioscience | 2019 |
|
Cholesterol lowering attenuates pressure overload-induced heart failure in mice with mild hypercholesterolemia
I Muthuramu, M Mishra, JP Aboumsallem, A Postnov, O Gheysens, BD Geest |
Aging | 2019 |
|
Hematopoietic Npc1 mutation shifts gut microbiota composition in Ldlr−/− mice on a high-fat, high-cholesterol diet
T Houben, J Penders, Y Oligschlaeger, IA dos Reis, MJ Bonder, DP Koonen, J Fu, MH Hofker, R Shiri-Sverdlov |
Scientific Reports | 2019 |
|
A Single Simulated Heliox Dive Modifies Endothelial Function in the Vascular Wall of ApoE Knockout Male Rats More Than Females
SB Ardestani, VV Matchkov, I Eftedal, M Pedersen |
Frontiers in physiology | 2019 |
|
Therapeutic targets of hypercholesterolemia: HMGCR and LDLR S Ma, W Sun, L Gao, S Liu |
Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy | 2019 |
|
Effects of GLP-1 receptor analogue liraglutide and DPP-4 inhibitor vildagliptin on the bone metabolism in ApoE−/− mice
L Zhang, P Li, Z Tang, Q Dou, B Feng |
Annals of translational medicine | 2019 |
|
Shexiang Baoxin Pill Alleviates the Atherosclerotic Lesions in Mice via Improving Inflammation Response and Inhibiting Lipid Accumulation in the Arterial Wall
L Lu, Y Qin, X Zhang, C Chen, X Xu, C Yu, X Guo |
Mediators of Inflammation | 2019 |
|
Confirmation of Ath26 locus on chromosome 17 and identification of Cyp4f13 as an atherosclerosis modifying gene
J Han, P Robinet, B Ritchey, H Andro, JD Smith |
Atherosclerosis | 2019 |
|
Dietary Cholesterol Is Highly Associated with Severity of Hyperlipidemia and Atherosclerotic Lesions in Heterozygous LDLR-Deficient Hamsters
J Wang, K He, C Yang, X Lin, X Zhang, Y Wang, G Liu, X Xian |
International journal of molecular sciences | 2019 |
|
Animal models of ischemic stroke and their impact on drug discovery
DM Hermann, A Popa-Wagner, C Kleinschnitz, TR Doeppner |
Expert Opinion on Drug Discovery | 2019 |
|
Review of the scientific evolution of gene therapy for the treatment of homozygous familial hypercholesterolaemia: past, present and future perspectives
R Rodriguez-Calvo, L Masana |
Journal of medical genetics | 2019 |
|
Vulnerable plaque and vulnerable blood: Two critical factors for spontaneous atherothrombosis in mouse models
AB Ouweneel, RA Verwilligen, MV Eck |
Atherosclerosis | 2019 |
|
Daily date vinegar consumption improves hyperlipidemia, β-carotenoid and inflammatory biomarkers in mildly hypercholesterolemic adults
Z Ali, H Ma, A Wali, I Ayim, MN Sharif |
Journal of Herbal Medicine | 2019 |
|
Pediatric Hepatology and Liver Transplantation
L D'Antiga |
2019 | |
|
Modelling of atherosclerosis in genetically modified animals
Natalia V Mushenkova, Volha I Summerhill, Yulia Yu Silaeva, Alexey V Deykin, Alexander N Orekhov |
American journal of translational research | 2019 |
|
Tissue-Engineered Vascular Grafts
B Walpoth, H Bergmeister, G Bowlin, D Kong, J Rotmans, P Zilla |
2019 | |
|
Using CRISPR/Cas9 to model human liver disease
M Alves-Bezerra, N Furey, CG Johnson, KD Bissig |
2019 | |
|
Apolipoprotein B100/Low-Density Lipoprotein Regulates Proteolysis and Functions of von Willebrand Factor under Arterial Shear.
Cao W, Abdelgawwad MS, Li J, Zheng XL |
Thrombosis and haemostasis | 2019 |
|
Not just correlative: a new pathway defines how an ALDH2 SNP contributes to atherosclerosis
Andrew A. Gibb, John Elrod |
Journal of Clinical Investigation | 2018 |
|
Osteopontin Deficiency Ameliorates Alport Pathology by Preventing Tubular Metabolic Deficits
Wen Ding, Keyvan Yousefi, Stefania Goncalves, Bradley J. Goldstein, Alfonso Sabater, Amy Kloosterboer, Portia Ritter, Guerline Lambert, Armando Mendez, Lina A. Shehadeh |
JCI Insight | 2018 |
|
Intracellular lipid metabolism impairs β-cell compensation during diet-induced obesity
Risheng Ye, Ruth Gordillo, Mengle Shao, Toshiharu Onodera, Zhe Chen, Shiuhwei Chen, Xiaoli Lin, Jeffrey A. SoRelle, Xiaohong Li, Miao Tang, mark keller, Regina Kuliawat, Alan D. Attie, Rana Gupta, William L. Holland, Bruce Beutler, Joachim Herz, Philipp E. Scherer |
Journal of Clinical Investigation | 2018 |
|
Hypercholesterolemia induces T cell expansion in humanized immune mice
Jonathan D Proto, Amanda Doran, Manikandan Subramanian, Hui Wang, Mingyou Zhang, Erdi Sozen, Christina Rymond, George Kuriakose, Vivette D'Agati, Robert Winchester, Megan Sykes, Yong-Guang Yang, Ira Tabas |
Journal of Clinical Investigation | 2018 |
|
Acetaldehyde Dehydrogenase 2 Interactions with LDLR and AMPK Regulate Foam Cell Formation
Shanshan Zhong, Luxiao Li, Yu-Lei Zhang, Lili Zhang, Jianhong Lu, Shuyuan Guo, Ningning Liang, Jing Ge, Mingjiang Zhu, Yongzhen Tao, Yun-Cheng Wu, Huiyong Yin |
Journal of Clinical Investigation | 2018 |
|
Conventional Dendritic Cells Impair Recovery after Myocardial Infarction
JS Lee, SJ Jeong, S Kim, L Chalifour, TJ Yun, MA Miah, B Li, A Majdoubi, A Sabourin, T Keler, JV Guimond, E Haddad, EY Choi, S Epelman, JH Choi, J Thibodeau, GT Oh, C Cheong |
Journal of immunology (Baltimore, Md. : 1950) | 2018 |
|
Insights From Pre-Clinical and Clinical Studies on the Role of Innate Inflammation in Atherosclerosis Regression
K Rahman, EA Fisher |
Frontiers in Cardiovascular Medicine | 2018 |
|
Apolipoprotein E and Atherosclerosis: From Lipoprotein Metabolism to MicroRNA Control of Inflammation
L Bouchareychas, R Raffai |
Journal of Cardiovascular Development and Disease | 2018 |
|
Protective Effects of Chinese Traditional Medicine Longhu Rendan against Atherosclerosis via Negative Regulation of LOX-1
S Yan, T Wu, N Li, L Zhang, J Song, Y Xu, S Wang, L Ding, J Jin, Y Liu, T Lan |
Evidence-Based Complementary and Alternative Medicine | 2018 |
|
CD6 expression has no effect on atherosclerosis in apolipoprotein E-deficient mice
J Han, G Enyindah-Asonye, F Lin, JD Smith |
BMC Research Notes | 2018 |
|
Consideration of Sex Differences in Design and Reporting of Experimental Arterial Pathology Studies—Statement From ATVB CouncilHighlights
P Robinet, DM Milewicz, LA Cassis, NJ Leeper, HS Lu, JD Smith |
Arteriosclerosis, thrombosis, and vascular biology | 2018 |
|
Blood-brain barrier dysfunction and recovery after ischemic stroke
X Jiang, AV Andjelkovic, L Zhu, T Yang, MV Bennett, J Chen, RF Keep, Y Shi |
Progress in Neurobiology | 2018 |
|
Loss of ACAT1 Attenuates Atherosclerosis Aggravated by Loss of NCEH1 in Bone Marrow-Derived Cells
H Yamazaki, M Takahashi, T Wakabayashi, K Sakai, D Yamamuro, A Takei, S Takei, S Nagashima, H Yagyu, M Sekiya, K Ebihara, S Ishibashi |
Journal of Atherosclerosis and Thrombosis | 2018 |
|
Murine models of vascular endothelial injury: Techniques and pathophysiology
Y Wu, S Su, Y Xie, J Shen, W Zhu, M Xiang |
Thrombosis Research | 2018 |
|
Liver X receptors in lipid signalling and membrane homeostasis
B Wang, P Tontonoz |
Nature Reviews Endocrinology | 2018 |
|
Milk cholesterol concentration in mice is not affected by high cholesterol diet- or genetically-induced hypercholesterolaemia
LG Dimova, MA Lohuis, VW Bloks, UJ Tietge, HJ Verkade |
Scientific Reports | 2018 |
|
Linking CD1-Restricted T Cells With Autoimmunity and Dyslipidemia: Lipid Levels Matter
S Bagchi, S Genardi, CR Wang |
Frontiers in immunology | 2018 |
|
A Novel Type 2 Diabetes Mouse Model of Combined Diabetic Kidney Disease and Atherosclerosis
KE Bornfeldt, F Kramer, A Batorsky, J Choi, KL Hudkins, P Tontonoz, CE Alpers, JE Kanter |
The American Journal of Pathology | 2018 |
|
Understanding the Impact of Dietary Cholesterol on Chronic Metabolic Diseases through Studies in Rodent Models
Á Vinué, A Herrero-Cervera, H González-Navarro |
Nutrients | 2018 |
|
Apoprotein E and Reverse Cholesterol Transport
G Getz, C Reardon |
International journal of molecular sciences | 2018 |
|
Hepatic NPC1L1 promotes hyperlipidemia in LDL receptor deficient mice
Y Wang, W Tang, P Yang, H Shin, Q Li |
Biochemical and Biophysical Research Communications | 2018 |
|
Current and Emerging Reconstituted HDL-apoA-I and HDL-apoE Approaches to Treat Atherosclerosis
EK Valanti, K Dalakoura-Karagkouni, D Sanoudou |
Journal of Personalized Medicine | 2018 |
|
Genetically engineered pigs as models for human disease
C Perleberg, A Kind, A Schnieke |
Disease models & mechanisms | 2018 |
|
A Familial Hypercholesterolemia Human Liver Chimeric Mouse Model Using Induced Pluripotent Stem Cell-derived Hepatocytes
J Yang, LY Wong, XY Tian, R Wei, WH Lai, KW Au, Z Luo, C Ward, WI Ho, DP Ibañez, H Liu, X Bao, B Qin, Y Huang, MA Esteban, HF Tse |
Journal of visualized experiments : JoVE | 2018 |
|
Progranulin in the hematopoietic compartment protects mice from atherosclerosis
AD Nguyen, TA Nguyen, RK Singh, D Eberlé, J Zhang, JP Abate, A Robles, S Koliwad, EJ Huang, FR Maxfield, TC Walther, RV Farese |
Atherosclerosis | 2018 |
|
Piezo1 and G q /G 11 promote endothelial inflammation depending on flow pattern and integrin activation
J Albarrán-Juárez, A Iring, SP Wang, S Joseph, M Grimm, B Strilic, N Wettschureck, TF Althoff, S Offermanns |
Journal of Experimental Medicine | 2018 |
|
Spontaneous severe hypercholesterolemia and atherosclerosis lesions in rabbits with deficiency of low-density lipoprotein receptor (LDLR) on exon 7
R Lu, T Yuan, Y Wang, T Zhang, Y Yuan, D Wu, M Zhou, Z He, Y Lu, Y Chen, J Fan, J Liang, Y Cheng |
EBioMedicine | 2018 |
|
Chlamydia pneumoniae Infection Exacerbates Atherosclerosis in ApoB100only/LDLR −/− Mouse Strain
I Lantos, V Endrész, DP Virok, A Szabó, X Lu, T Mosolygó, K Burián |
BioMed Research International | 2018 |
|
Long-term Western diet fed apolipoprotein E-deficient rats exhibit only modest early atherosclerotic characteristics
I Rune, B Rolin, J Lykkesfeldt, DS Nielsen, Ł Krych, JE Kanter, KE Bornfeldt, P Kihl, K Buschard, K Josefsen, JJ Fels, A Mortensen, B Christoffersen, RK Kirk, AK Hansen |
Scientific Reports | 2018 |
|
Age-Related Changes in the Behavior of Apolipoprotein E Knockout Mice
D Fuentes, N Fernández, Y García, T García, A Morales, R Menéndez |
Behavioral Science | 2018 |
|
Imiquimod-Induced Psoriasis-Like Skin Lesions Do Not Accelerate Atherosclerosis in Low-Density Lipoprotein Receptor–Deficient Mice
M Madsen, PR Hansen, LB Nielsen, RM Cardoso, M van Eck, TX Pedersen |
The American Journal of Pathology | 2018 |
|
Characterization of Atherosclerosis Formation in a Murine Model of Type IIa Human Familial Hypercholesterolemia
C Miyajima, T Iwaki, K Umemura, VA Ploplis, FJ Castellino |
BioMed Research International | 2018 |
|
Intermittent Hypoxia and Hypercapnia, a Hallmark of Obstructive Sleep Apnea, Alters the Gut Microbiome and Metabolome
A Tripathi, AV Melnik, J Xue, O Poulsen, MJ Meehan, G Humphrey, L Jiang, G Ackermann, D McDonald, D Zhou, R Knight, PC Dorrestein, GG Haddad, JK Jansson |
mSystems | 2018 |
|
Metabolomic Approach to Redox and Nitrosative Reactions in Cardiovascular Diseases
M Deidda, A Noto, PP Bassareo, CC Dessalvi, G Mercuro |
Frontiers in physiology | 2018 |
|
Activities of purine converting enzymes in heart, liver and kidney mice LDLR−/− and Apo E−/−
IM Rybakowska, B Kutryb-Zając, R Milczarek, B Łukasz, EM Slominska, RT Smolenski |
Nucleosides, Nucleotides and Nucleic Acids | 2018 |
|
Reduced cognitive function, increased blood-brain-barrier transport and inflammatory responses, and altered brain metabolites in LDLr -/-and C57BL/6 mice fed a western diet
JM Rutkowsky, LL Lee, M Puchowicz, MS Golub, DE Befroy, DW Wilson, S Anderson, G Cline, J Bini, K Borkowski, TA Knotts, JC Rutledge, MA Deli |
PloS one | 2018 |
|
AAV8-mediated overexpression of mPCSK9 in liver differs between male and female mice
AE Vozenilek, CM Blackburn, RM Schilke, S Chandran, R Castore, RL Klein, MD Woolard |
Atherosclerosis | 2018 |
|
LDL Receptor Gene-ablated Hamsters: A Rodent Model of Familial Hypercholesterolemia With Dominant Inheritance and Diet-induced Coronary Atherosclerosis
X Guo, M Gao, Y Wang, X Lin, L Yang, N Cong, X An, F Wang, K Qu, L Yu, Y Wang, J Wang, H Zhu, X Xian, G Liu |
EBioMedicine | 2018 |
|
Analyzing 2000 in Vivo Drug Delivery Data Points Reveals Cholesterol Structure Impacts Nanoparticle Delivery
K Paunovska, CJ Gil, MP Lokugamage, CD Sago, M Sato, GN Lando, MG Castro, AV Bryksin, JE Dahlman |
ACS Nano | 2018 |
|
Mitochondrial Diseases
E Taskin, C Guven, Y Sevgiler |
2018 | |
|
Experimental Animal Models of Human Diseases - An Effective Therapeutic Strategy
I Bartholomew |
2018 | |
|
Endocytosis of lipoproteins
P Zanoni, S Velagapudi, M Yalcinkaya, L Rohrer, A von Eckardstein |
Atherosclerosis | 2018 |
|
Predilection of Low Protein C-induced Spontaneous Atherothrombosis for the Right Coronary Sinus in Apolipoprotein E deficient mice
M Heestermans, AB Ouweneel, J Hassan, M Kloosterman, PH Reitsma, MJ Gijbels, BJ van Vlijmen, M van Eck |
Scientific Reports | 2018 |
|
A severe atherosclerosis mouse model on the resistant NOD background
X Wang, R Huang, L Zhang, S Li, J Luo, Y Gu, Z Chen, Q Zheng, T Chao, W Zheng, X Qi, L Wang, Y Wen, Y Liang, L Lu |
Disease models & mechanisms | 2018 |
|
Apolipoprotein E deficiency accelerates atherosclerosis development in miniature pigs
B Fang, X Ren, Y Wang, Z Li, L Zhao, M Zhang, C Li, Z Zhang, L Chen, X Li, J Liu, Q Xiong, L Zhang, Y Jin, X Liu, L Li, H Wei, H Yang, R Li, Y Dai |
Disease models & mechanisms | 2018 |
|
Hydrophobicity drives the systemic distribution of lipid-conjugated siRNAs via lipid transport pathways
MF Osborn, AH Coles, A Biscans, RA Haraszti, L Roux, S Davis, S Ly, D Echeverria, MR Hassler, BM Godinho, M Nikan, A Khvorova |
Nucleic Acids Research | 2018 |
|
Proteomic Analysis of Liver from Human Lipoprotein(a) Transgenic Mice Shows an Oxidative Stress and Lipid Export Response
EJ Rodger, CM Porteous, GT Jones, M Legge, T Kleffmann, SP McCormick |
BioMed Research International | 2018 |
|
Endocytosis and Signaling
C Lamaze, I Prior |
2018 | |
|
Peptide Amphiphile Nanostructures for Targeting of Atherosclerotic Plaque and Drug Delivery
MM So, NA Mansukhani, EB Peters, MS Albaghdadi, Z Wang, CM Pérez, MR Kibbe, SI Stupp |
Advanced Biosystems | 2018 |
|
Endovascular Interventions
JM Wiley, C Sanina, P Faries, ID Conde, GD Dangas, P Krishnan |
2018 | |
|
Strobilanthes crispus Extract Reduces RespiStrobilanthes crispus Extract Reduces Respiratory Exchange Ratio in Obese Mice Fed High Fat and Low Fat Diets
N Zawawi, M Ismail |
The Malaysian Journal of Medical Sciences : MJMS | 2018 |
|
Low Phytanic Acid-Concentrated DHA Prevents Cognitive Deficit and Regulates Alzheimer Disease Mediators in an ApoE−/− Mice Experimental Model
M Ruiz-Roso, V Echeverry-Alzate, B Ruiz-Roso, J Quintela, S Ballesteros, V Lahera, N de las Heras, J López-Moreno, B Martín-Fernández |
Nutrients | 2018 |
|
Hypoxia/reperfusion predisposes to atherosclerosis
R Finsterwalder, MK Ganesan, H Leb, A Habertheuer, J Basílio, I Lang, M Krunic, D Wiedemann, P Petzelbauer, G Pintus |
PloS one | 2018 |
|
Atherogenesis and Metabolic Dysregulation in LDL Receptor Knockout Rats
Srinivas Dwarakanath Sithu, Marina V. Malovichko, Krista A Riggs, Nalinie S Wickramasinghe, Millicent G Winner, Abhinav Agarwal, Rihab E Hamed-Berair, Anuradha Kalani, Daniel W Riggs, Aruni Bhatnagar, Sanjay Srivastava |
JCI Insight | 2017 |
|
E2F1 inhibits circulating cholesterol clearance by regulating PCSK9 expression in the liver
Qiuwen Lai, Albert Giralt, Cedric Le May, Lianjun Zhang, Bertrand Cariou, Pierre-Damien Denechaud, Lluis Fajas |
JCI Insight | 2017 |
|
Hepatic JAK2 protects against atherosclerosis through circulating IGF-1
Tharini Sivasubramaniyam, Stephanie A. Schroer, Angela Li, Cynthia T. Luk, Sally Yu Shi, Rickvinder Besla, David W. Dodington, Adam Metherel, Alex Kitson, Jara J. Brunt, Joshua Lopes, Kay-Uwe Wagner, Richard P. Bazinet, Michelle Bendeck, Clinton Robbins, Minna Woo |
JCI Insight | 2017 |
|
Pharmacological inhibition of protein tyrosine phosphatase 1B protects against atherosclerotic plaque formation in the LDLR −/− mouse model of atherosclerosis
D Thompson, N Morrice, L Grant, SL Sommer, EK Lees, N Mody, HM Wilson, M Delibegovic |
Clinical Science | 2017 |
|
Functional Roles of the Interaction of APP and Lipoprotein Receptors
T Pohlkamp, CR Wasser, J Herz |
Frontiers in molecular neuroscience | 2017 |
|
The Immunology of Cardiovascular Homeostasis and Pathology
S Sattler, T Kennedy-Lydon |
The Immunology of Cardiovascular Homeostasis and Pathology | 2017 |
|
The Immunology of Cardiovascular Homeostasis and Pathology
S Sattler, T Kennedy-Lydon |
The Immunology of Cardiovascular Homeostasis and Pathology | 2017 |
|
Murine ultrasound-guided transabdominal para-aortic injections of self-assembling type I collagen oligomers
AA Yrineo, AR Adelsperger, AC Durkes, MR Distasi, SL Voytik-Harbin, MP Murphy, CJ Goergen |
Journal of Controlled Release | 2017 |
|
Clonal Hematopoiesis and Risk of Atherosclerotic Cardiovascular Disease
S Jaiswal, P Natarajan, AJ Silver, CJ Gibson, AG Bick, E Shvartz, M McConkey, N Gupta, S Gabriel, D Ardissino, U Baber, R Mehran, V Fuster, J Danesh, P Frossard, D Saleheen, O Melander, GK Sukhova, D Neuberg, P Libby, S Kathiresan, BL Ebert |
New England Journal of Medicine | 2017 |
|
Diabetes-mediated myelopoiesis and the relationship to cardiovascular risk: Diabetes myelopoiesis and cardiovascular risk
TJ Barrett, AJ Murphy, IJ Goldberg, EA Fisher |
Annals of the New York Academy of Sciences | 2017 |
|
Expression of SREBP-1c Requires SREBP-2-mediated Generation of a Sterol Ligand for LXR in Livers of Mice
S Rong, VA Cortés, S Rashid, NN Anderson, JG McDonald, G Liang, YA Moon, RE Hammer, JD Horton |
eLife | 2017 |
|
Cholesterol Homeostasis
IC Gelissen, AJ Brown |
Cholesterol Homeostasis | 2017 |
|
Dyslipidemic Diet-Induced Monocyte “Priming” and Dysfunction in Non-Human Primates Is Triggered by Elevated Plasma Cholesterol and Accompanied by Altered Histone Acetylation
JD Short, S Tavakoli, HN Nguyen, A Carrera, C Farnen, LA Cox, R Asmis |
Frontiers in immunology | 2017 |
|
News on the molecular regulation and function of hepatic low-density lipoprotein receptor and LDLR-related protein 1:
B de Sluis, M Wijers, J Herz |
Current Opinion in Lipidology | 2017 |
|
Intermittent Hypoxia and Hypercapnia Accelerate Atherosclerosis, Partially via Trimethylamine-Oxide
J Xue, D Zhou, O Poulsen, T Imamura, YH Hsiao, TH Smith, A Malhotra, P Dorrestein, R Knight, GG Haddad |
American journal of respiratory cell and molecular biology | 2017 |
|
Inflammation
BE Clausen, JD Laman |
Inflammation | 2017 |
|
Inflammation
BE Clausen, JD Laman |
Inflammation | 2017 |
|
Inflammation
BE Clausen, JD Laman |
Inflammation | 2017 |
|
Models of retinal diseases and their applicability in drug discovery
G Malek, J Busik, MB Grant, M Choudhary |
Expert Opinion on Drug Discovery | 2017 |
|
Severe pulmonary hypertension in aging female apolipoprotein E-deficient mice is rescued by estrogen replacement therapy
S Umar, R Partow-Navid, G Ruffenach, A Iorga, S Moazeni, M Eghbali |
Biology of sex differences | 2017 |
|
Apolipoprotein E Deficiency Increases Remnant Lipoproteins and Accelerates Progressive Atherosclerosis, But Not Xanthoma Formation, in Gene-Modified Minipigs
J Shim, CB Poulsen, MK Hagensen, T Larsen, PM Heegaard, C Christoffersen, L Bolund, M Schmidt, Y Liu, J Li, R Li, H Callesen, JF Bentzon, CB Sørensen |
JACC: Basic to Translational Science | 2017 |
|
Generation of Human Liver Chimeric Mice with Hepatocytes from Familial Hypercholesterolemia Induced Pluripotent Stem Cells
J Yang, Y Wang, T Zhou, LY Wong, XY Tian, X Hong, WH Lai, KW Au, R Wei, Y Liu, LH Cheng, G Liang, Z Huang, W Fan, P Zhao, X Wang, DP Ibañez, Z Luo, Y Li, X Zhong, S Chen, D Wang, L Li, L Lai, B Qin, X Bao, AP Hutchins, CW Siu, Y Huang, MA Esteban, HF Tse |
Stem Cell Reports | 2017 |
|
Modeling hypercholesterolemia and vascular lipid accumulation in LDL receptor mutant zebrafish
C Liu, YS Kim, J Kim, J Pattison, A Kamaid, YI Miller |
Journal of lipid research | 2017 |
|
Mechanistic understanding of in vivo protein corona formation on polymeric nanoparticles and impact on pharmacokinetics
N Bertrand, P Grenier, M Mahmoudi, EM Lima, EA Appel, F Dormont, JM Lim, R Karnik, R Langer, OC Farokhzad |
Nature Communications | 2017 |
|
Somatic genome editing with CRISPR/Cas9 generates and corrects a metabolic disease
KE Jarrett, CM Lee, YH Yeh, RH Hsu, R Gupta, M Zhang, PJ Rodriguez, CS Lee, BK Gillard, KD Bissig, HJ Pownall, JF Martin, G Bao, WR Lagor |
Scientific Reports | 2017 |
|
CB1 and CB2 Receptor Pharmacology.
Howlett AC, Abood ME |
Advances in pharmacology (San Diego, Calif.) | 2017 |
|
Matrix Metalloproteinases, Vascular Remodeling, and Vascular Disease.
Wang X, Khalil RA |
Advances in pharmacology (San Diego, Calif.) | 2017 |
|
Synaptotoxic Signaling by Amyloid Beta Oligomers in Alzheimer's Disease Through Prion Protein and mGluR5.
Brody AH, Strittmatter SM |
Advances in pharmacology (San Diego, Calif.) | 2017 |
|
Phosphorylation of the Amino Terminus of the Dopamine Transporter: Regulatory Mechanisms and Implications for Amphetamine Action.
Karam CS, Javitch JA |
Advances in pharmacology (San Diego, Calif.) | 2017 |
|
The Role of Serine Racemase in the Pathophysiology of Brain Disorders.
Coyle JT, Balu DT |
Advances in pharmacology (San Diego, Calif.) | 2017 |
|
Maternal-fetal cholesterol transport in the second half of mouse pregnancy does not involve LDL receptor-related protein 2
MV Zwier, ME Baardman, TH van Dijk, A Jurdzinski, LJ Wisse, VW Bloks, RM Berger, MC DeRuiter, AK Groen, T Plösch |
Acta physiologica (Oxford, England) | 2017 |
|
Mouse models of atherosclerosis: a historical perspective and recent advances
YT Lee, HY Lin, YW Chan, KH Li, OT To, BP Yan, T Liu, G Li, WT Wong, W Keung, G Tse |
Lipids in Health and Disease | 2017 |
|
Green fluorescent protein-tagged apolipoprotein E: A useful marker for the study of hepatic lipoprotein egress
CN Takacs, U Andreo, RL Belote, J Pulupa, MA Scull, CE Gleason, CM Rice, SM Simon |
Traffic (Copenhagen, Denmark) | 2017 |
|
High Plasma Lipid Levels Reduce Efficacy of Adenovirus-Mediated Gene Therapy
AM Kivelä, J Huusko, E Gurzeler, A Laine, MH Dijkstra, G Dragneva, CB Andersen, SK Moestrup, S Ylä-Herttuala |
Scientific Reports | 2017 |
|
HVC1 ameliorates hyperlipidemia and inflammation in LDLR−/− mice
SY Cheon, KS Chung, KJ Lee, HY Choi, IH Ham, DH Jung, YY Cha, HJ An |
BMC complementary and alternative medicine | 2017 |
|
The phenomenon of atherosclerosis reversal and regression: Lessons from animal models
DA Chistiakov, VA Myasoedova, VV Revin, AN Orekhov, YV Bobryshev |
Experimental and Molecular Pathology | 2017 |
|
PCSK9 and diabetes: is there a link?
AA Momtazi, M Banach, M Pirro, EA Stein, A Sahebkar |
Drug Discovery Today | 2017 |
|
Intimal hyperplasia induced by vascular intervention causes lipoprotein retention and accelerated atherosclerosis
S Kijani, AM Vázquez, M Levin, J Borén, P Fogelstrand |
Physiological Reports | 2017 |
|
Modern Magnetic Resonance
GA Webb |
Modern Magnetic Resonance | 2017 |
|
Deletion of a Distal RANKL Gene Enhancer Delays Progression of Atherosclerotic Plaque Calcification in Hypercholesterolemic Mice: RANKL D ISTAL E NHANCER AND A THEROSCLEROTIC P LAQUES
S Shamsuzzaman, M Onal, HC st John, JW Pike |
Journal of Cellular Biochemistry | 2017 |
|
High-cholesterol diet does not alter gut microbiota composition in mice
LG Dimova, N Zlatkov, HJ Verkade, BE Uhlin, UJ Tietge |
Nutrition & Metabolism | 2017 |
|
Hypercholesterolemia Causes Circadian Dysfunction: A Potential Risk Factor for Cardiovascular Disease
M Akashi, R Matsumura, T Matsuo, Y Kubo, H Komoda, K Node |
EBioMedicine | 2017 |
|
Gugulipid causes hypercholesterolemia leading to endothelial dysfunction, increased atherosclerosis, and premature death by ischemic heart disease in male mice
A Leiva, S Contreras-Duarte, L Amigo, E Sepúlveda, M Boric, V Quiñones, D Busso, A Rigotti, MC Vinci |
PloS one | 2017 |
|
VLDL/LDL acts as a drug carrier and regulates the transport and metabolism of drugs in the body
H Yamamoto, T Takada, Y Yamanashi, M Ogura, Y Masuo, M Harada-Shiba, H Suzuki |
Scientific Reports | 2017 |
|
Distinct roles for dietary lipids and Porphyromonas gingivalis infection on atherosclerosis progression and the gut microbiota
CD Kramer, AM Simas, X He, RR Ingalls, EO Weinberg, CA Genco |
Anaerobe | 2017 |
|
Elevated tumor LDLR expression accelerates LDL cholesterol-mediated breast cancer growth in mouse models of hyperlipidemia
EJ Gallagher, Z Zelenko, BA Neel, IM Antoniou, L Rajan, N Kase, D LeRoith |
Oncogene | 2017 |
|
Proteases in Human Diseases
S Chakraborti, T Chakraborti, NS Dhalla |
Proteases in Human Diseases | 2017 |
|
Quantitative trait locus mapping in mice identifies phospholipase Pla2g12a as novel atherosclerosis modifier
A Nicolaou, BH Northoff, K Sass, J Ernst, A Kohlmaier, K Krohn, C Wolfrum, D Teupser, LM Holdt |
Atherosclerosis | 2017 |
|
Accelerated atherogenesis in completely ligated common carotid artery of apolipoprotein E-deficient mice
Z Chang, C Huangfu, AT Grainger, J Zhang, Q Guo, W Shi |
Oncotarget | 2017 |
|
HDL functionality in familial hypercholesterolemia: effects of treatment modalities and pharmacological interventions
S Ganjali, AA Momtazi, M Banach, PT Kovanen, AM Gotto, A Sahebkar |
Drug Discovery Today | 2017 |
|
Hempseed Peptides Exert Hypocholesterolemic Effects with a Statin-Like Mechanism
C Zanoni, G Aiello, A Arnoldi, C Lammi |
Journal of Agricultural and Food Chemistry | 2017 |
|
Metabolic parameters and responsiveness of isolated iliac artery in LDLr(-/-) mice: role of aerobic exercise training
Nádia F Garcia, Amanda Cs Sponton, Maria A Delbin, Juliana M Parente, Michele M Castro, Angelina Zanesco, Camila de Moraes |
American Journal of Cardiovascular Disease | 2017 |
|
Elevated plasma levels of LDL-cholesterol promote dissecting thoracic aortic aneurysms in angiotensin II-induced mice
H Tanaka, Y Iida, T Iwaki, Y Suzuki, H Sano, C Miyajima, N Zaima, T Sasaki, A Sumioka, S Hakamata, H Shimizu, K Umemura, T Urano |
Annals of Vascular Surgery | 2017 |
|
Recent Advances in Managing Atherosclerosis via Nanomedicine
CK Chan, L Zhang, CK Cheng, H Yang, Y Huang, XY Tian, CH Choi |
Small | 2017 |
|
Differential action of glucocorticoids on apolipoprotein E gene expression in macrophages and hepatocytes
VG Trusca, EV Fuior, IM Fenyo, D Kardassis, M Simionescu, AV Gafencu, K Roemer |
PloS one | 2017 |
|
Sex differences in the LDL receptor knockout mouse model of atherosclerosis
NA Mansukhani, Z Wang, VP Shively, ME Kelly, JM Vercammen, MR Kibbe |
Artery Research | 2017 |
|
The AT04A vaccine against proprotein convertase subtilisin/kexin type 9 reduces total cholesterol, vascular inflammation, and atherosclerosis in APOE*3Leiden.CETP mice
C Landlinger, MG Pouwer, C Juno, JW van der Hoorn, EJ Pieterman, JW Jukema, G Staffler, HM Princen, G Galabova |
European Heart Journal | 2017 |
|
A wild-type mouse-based model for the regression of inflammation in atherosclerosis
M Peled, H Nishi, A Weinstock, TJ Barrett, F Zhou, A Quezada, EA Fisher, C Schulz |
PloS one | 2017 |
|
Hypercholesterolemia induced cerebral small vessel disease
P Kraft, MK Schuhmann, C Garz, S Jandke, D Urlaub, S Mencl, A Zernecke, HJ Heinze, RO Carare, C Kleinschnitz, S Schreiber, J Minnerup |
PloS one | 2017 |
|
Increased plasma lipid levels exacerbate muscle pathology in the mdx mouse model of Duchenne muscular dystrophy
N Milad, Z White, AY Tehrani, S Sellers, FM Rossi, P Bernatchez |
Skeletal Muscle | 2017 |
|
Discovery and Development of Calcium Channel Blockers
T Godfraind |
Frontiers in pharmacology | 2017 |
|
Characterisation of the vascular pathology in Sigmodon hispidus (Rodentia: Cricetidae) following experimental infection with Angiostrongylus costaricensis (Nematoda: Metastrongylidae)
DI de Vasconcelos, EM Mota, M Pelajo-Machado |
Memórias do Instituto Oswaldo Cruz | 2017 |
|
mTOR drives cerebral blood flow and memory deficits in LDLR −/− mice modeling atherosclerosis and vascular cognitive impairment
JB Jahrling, AL Lin, N DeRosa, SA Hussong, CE Skike, M Girotti, M Javors, Q Zhao, LA Maslin, R Asmis, V Galvan |
Journal of Cerebral Blood Flow & Metabolism | 2017 |
|
Steryl ester synthesis, storage and hydrolysis: A contribution to sterol homeostasis
M Korber, I Klein, G Daum |
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids | 2017 |
|
Regulation of PCSK9 by nutraceuticals
AA Momtazi, M Banach, M Pirro, N Katsiki, A Sahebkar |
Pharmacological research : the official journal of the Italian Pharmacological Society | 2017 |
|
Advances in transgenic animal models and techniques
S Ménoret, L Tesson, S Remy, C Usal, LH Ouisse, L Brusselle, V Chenouard, I Anegon |
Transgenic Research | 2017 |
|
Tissue Uptake Mechanisms Involved in the Clearance of Non-Protein Nanoparticles that Mimic LDL Composition: A Study with Knockout and Transgenic Mice
EN Daminelli, P Fotakis, CH Mesquita, RC Maranhão, VI Zannis |
Lipids | 2017 |
|
Sphingolipids in obesity and related complications
Krishna M Boini, Min Xia, Saisudha Koka, Todd W B Gehr, Pin-Lan Li |
Frontiers in bioscience : a journal and virtual library | 2017 |
|
Advances in transgenic animal models and techniques.
Ménoret S, Tesson L, Remy S, Usal C, Ouisse LH, Brusselle L, Chenouard V, Anegon I |
Transgenic Research | 2017 |
|
Tissue Uptake Mechanisms Involved in the Clearance of Non-Protein Nanoparticles that Mimic LDL Composition: A Study with Knockout and Transgenic Mice.
Daminelli EN, Fotakis P, Mesquita CH, Maranhão RC, Zannis VI |
Lipids | 2017 |
|
Interaction between integrin α5 and PDE4D regulates endothelial inflammatory signalling
S Yun, M Budatha, JE Dahlman, BG Coon, RT Cameron, R Langer, DG Anderson, G Baillie, MA Schwartz |
Nature Cell Biology | 2016 |
|
Immune-inflammatory responses in atherosclerosis: Role of an adaptive immunity mainly driven by T and B cells
DA Chistiakov, AN Orekhov, YV Bobryshev |
Immunobiology | 2016 |
|
Combined B, T and NK Cell Deficiency Accelerates Atherosclerosis in BALB/c Mice
F Cheng, L Twardowski, K Reifenberg, K Winter, A Canisius, E Pross, J Fan, E Schmitt, LD Shultz, KJ Lackner, M Torzewski, GP Bonsal |
PloS one | 2016 |
|
Translational atherosclerosis research: From experimental models to coronary artery disease in humans
CA Gleissner |
Atherosclerosis | 2016 |
|
The potential impact of new generation transgenic methods on creating rabbit models of cardiac diseases
Z Bősze, P Major, I Baczkó, KE Odening, L Bodrogi, L Hiripi, A Varró |
Progress in Biophysics and Molecular Biology | 2016 |
|
Aerobic exercise training protects against endothelial dysfunction by increasing nitric oxide and hydrogen peroxide production in LDL receptor-deficient mice
DM Guizoni, GG Dorighello, HC Oliveira, MA Delbin, MH Krieger, AP Davel |
Journal of Translational Medicine | 2016 |
|
An Update on the Use of Animal Models in Diabetic Nephropathy Research
B Betz, BR Conway |
Current Diabetes Reports | 2016 |
|
HDL functionality in reverse cholesterol transport — Challenges in translating data emerging from mouse models to human disease
M Lee-Rueckert, JC Escola-Gil, PT Kovanen |
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids | 2016 |
|
Scavenger Receptor Class B Type 1 Deletion Led to Coronary Atherosclerosis and Ischemic Heart Disease in Low-density Lipoprotein Receptor Knockout Mice on Modified Western-type Diet
J Liao, X Guo, M Wang, C Dong, M Gao, H Wang, A Kayoumu, Q Shen, Y Wang, F Wang, W Huang, G Liu |
Journal of Atherosclerosis and Thrombosis | 2016 |
|
Low-Density Lipoprotein Receptor-Related Protein-1 Protects Against Hepatic Insulin Resistance and Hepatic Steatosis
Y Ding, X Xian, WL Holland, S Tsai, J Herz |
EBioMedicine | 2016 |
|
Cholesterol metabolism: A review of how ageing disrupts the biological mechanisms responsible for its regulation
AE Morgan, KM Mooney, SJ Wilkinson, NA Pickles, MT Auley |
Ageing Research Reviews | 2016 |
|
Dysregulation of the Low-Density Lipoprotein Receptor Pathway Is Involved in Lipid Disorder-Mediated Organ Injury
Y Zhang, KL Ma, XZ Ruan, BC Liu |
International journal of biological sciences | 2016 |
|
Severe Atherosclerosis and Hypercholesterolemia in Mice Lacking Both the Melanocortin Type 4 Receptor and Low Density Lipoprotein Receptor
V Lede, C Franke, A Meusel, D Teupser, A Ricken, J Thiery, J Schiller, D Huster, T Schöneberg, A Schulz, Y Zhang |
PloS one | 2016 |
|
A lipidomics study reveals hepatic lipid signatures associating with deficiency of the LDL receptor in a rat model
HY Wang, C Quan, C Hu, B Xie, Y Du, L Chen, W Yang, L Yang, Q Chen, B Shen, B Hu, Z Zheng, H Zhu, X Huang, G Xu, S Chen |
Biology Open | 2016 |
|
Applications and Limitations of Mouse Models for Understanding Human Atherosclerosis
M von Scheidt, Y Zhao, Z Kurt, C Pan, L Zeng, X Yang, H Schunkert, AJ Lusis |
Cell Metabolism | 2016 |
|
Hypertension and decreased aortic compliance due to reduced elastin amounts do not increase atherosclerotic plaque accumulation in Ldlr−/− mice
JA Maedeker, KV Stoka, SA Bhayani, WS Gardner, L Bennett, JD Procknow, MC Staiculescu, TA Walji, CS Craft, JE Wagenseil |
Atherosclerosis | 2016 |
|
The role of endothelial mechanosensitive genes in atherosclerosis and omics approaches
RD Simmons, S Kumar, H Jo |
Archives of Biochemistry and Biophysics | 2016 |
|
With mouse age comes wisdom: A review and suggestions of relevant mouse models for age-related conditions
S Drechsler, MA Lynch, S Novella, H González-Navarro, S Hecimovic, E Barini, V Tucci, RE Castro, RE Vandenbroucke, M Osuchowski, PK Potter |
Mechanisms of Ageing and Development | 2016 |
|
Phenotypic transformation of intimal and adventitial lymphatics in atherosclerosis: a regulatory role for soluble VEGF receptor 2
M Taher, S Nakao, S Zandi, MI Melhorn, KC Hayes, A Hafezi-Moghadam |
The FASEB Journal | 2016 |
|
Molecular Imaging of Vulnerable Atherosclerotic Plaques in Animal Models
S Gargiulo, M Gramanzini, M Mancini |
International journal of molecular sciences | 2016 |
|
Myeloid Deletion of α1AMPK Exacerbates Atherosclerosis in LDL Receptor Knockout (LDLRKO) Mice
Q Cao, X Cui, R Wu, L Zha, X Wang, JS Parks, L Yu, H Shi, B Xue |
Diabetes | 2016 |
|
Identification of roles for H264, H306, H439, and H635 in acid-dependent lipoprotein release by the LDL receptor
H Dong, Z Zhao, DG LeBrun, P Michaely |
Journal of lipid research | 2016 |
|
Endocytic adaptors Arh and Dab2 control homeostasis of circulatory cholesterol
W Tao, R Moore, Y Meng, ER Smith, XX Xu |
Journal of lipid research | 2016 |
|
ApoE deficiency exacerbates the development and sustainment of a semi-chronic K/BxN serum transfer-induced arthritis model
AM Archer, R Saber, S Rose, A Shaffer, AV Misharin, FN Tsai, GK Haines, S Dominguez, M Eren, DE Vaughan, CM Cuda, H Perlman |
Journal of Translational Medicine | 2016 |
|
HDL is redundant for adrenal steroidogenesis in LDLR knockout mice with a human-like lipoprotein profile
M Hoekstra, MV Eck |
Journal of lipid research | 2016 |
|
The role of HDL in plaque stabilization and regression: basic mechanisms and clinical implications
JE Feig, JL Feig, GD Dangas |
Coronary Artery Disease | 2016 |
|
Betulin attenuates atherosclerosis in apoE−/− mice by up-regulating ABCA1 and ABCG1
Y Gui, H Yan, F Gao, C Xi, H Li, Y Wang |
Acta Pharmacologica Sinica | 2016 |
|
The Apoe−/− mouse model: a suitable model to study cardiovascular and respiratory diseases in the context of cigarette smoke exposure and harm reduction
GL Sasso, WK Schlage, S Boué, E Veljkovic, MC Peitsch, J Hoeng |
Journal of Translational Medicine | 2016 |
|
The western-type diet induces anti-HMGB1 autoimmunity in Apoe−/− mice
Y Pan, H Ke, Z Yan, Y Geng, N Asner, S Palani, G Munirathinam, S Dasari, KC Nitiss, S Bliss, P Patel, H Shen, CA Reardon, GS Getz, A Chen, G Zheng |
Atherosclerosis | 2016 |
|
Loss of Reelin protects against atherosclerosis by reducing leukocyte-endothelial cell adhesion and lesion macrophage accumulation
Y Ding, L Huang, X Xian, IS Yuhanna, CR Wasser, M Frotscher, C Mineo, PW Shaul, J Herz |
Science signaling | 2016 |
|
Current Protocols in Mouse Biology: Mouse Models of Nonalcoholic Steatohepatitis
A Jacobs, AS Warda, J Verbeek, D Cassiman, P Spincemaille |
Current Protocols in Mouse Biology: Mouse Models of Nonalcoholic Steatohepatitis | 2016 |
|
Do the Apoe −/− and Ldlr −/– Mice Yield the Same Insight on Atherogenesis?Highlights: Table
GS Getz, CA Reardon |
Arteriosclerosis, thrombosis, and vascular biology | 2016 |
|
Zebrafish Models for Dyslipidemia and Atherosclerosis Research
A Schlegel |
Frontiers in Endocrinology | 2016 |
|
Omics-based approaches to understand mechanosensitive endothelial biology and atherosclerosis: Omics-based approaches in atherosclerosis
RD Simmons, S Kumar, SR Thabet, S Sur, H Jo |
Wiley Interdisciplinary Reviews Systems Biology and Medicine | 2016 |
|
ApoE knockout rabbits: A novel model for the study of human hyperlipidemia
M Niimi, D Yang, S Kitajima, B Ning, C Wang, S Li, E Liu, J Zhang, YE Chen, J Fan |
Atherosclerosis | 2016 |
|
Translational Cardiometabolic Genomic Medicine
A Naj |
Translational Cardiometabolic Genomic Medicine | 2016 |
|
Lipoproteins and lipoprotein mimetics for imaging and drug delivery
CS Thaxton, JS Rink, PC Naha, DP Cormode |
Advanced Drug Delivery Reviews | 2016 |
|
Cholesteryl Ester Transfer Protein (CETP) expression does not affect glucose homeostasis and insulin secretion: studies in human CETP transgenic mice
HF Raposo, EC Vanzela, JA Berti, HC Oliveira |
Lipids in Health and Disease | 2016 |
|
Harder-to-Treat Patients: Recognizing Them and Adapting Treatment Strategies
MD Miedema, SS Virani |
The American Journal of Cardiology | 2016 |
|
Mode-of-action evaluation for the effect of trans fatty acids on low-density lipoprotein cholesterol
JF Reichard, LT Haber |
Food and Chemical Toxicology | 2016 |
|
Discoidin Domain Receptors in Health and Disease
K Kano, KT Kusakabe, Y Kiso |
Discoidin Domain Receptors in Health and Disease | 2016 |
|
Construction of minicircle DNA vectors capable of correcting familial hypercholesterolemia phenotype in a LDLR-deficient mouse model
X Hou, R Jiao, X Guo, T Wang, P Chen, D Wang, Y Chen, CY He, ZY Chen |
Gene Therapy | 2016 |
|
Streptococcal serum opacity factor promotes cholesterol ester metabolism and bile acid secretion in vitro and in vivo
BK Gillard, PJ Rodriguez, DW Fields, JL Raya, WR Lagor, C Rosales, HS Courtney, AM Gotto, HJ Pownall |
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids | 2016 |
|
USF1 deficiency activates brown adipose tissue and improves cardiometabolic health
PP Laurila, J Soronen, S Kooijman, S Forsstrom, MR Boon, I Surakka, E Kaiharju, CP Coomans, SA van Berg, A Autio, AP Sarin, J Kettunen, E Tikkanen, T Manninen, J Metso, R Silvennoinen, K Merikanto, M Ruuth, J Perttila, A Makela, A Isomi, AM Tuomainen, A Tikka, UA Ramadan, I Seppala, T Lehtimaki, J Eriksson, A Havulinna, A Jula, PJ Karhunen, V Salomaa, M Perola, C Ehnholm, M Lee-Rueckert, MV Eck, A Roivainen, MR Taskinen, L Peltonen, E Mervaala, A Jalanko, E Hohtola, VM Olkkonen, S Ripatti, PT Kovanen, PC Rensen, A Suomalainen, M Jauhiainen |
Science Translational Medicine | 2016 |
|
Is there an association between hypercholesterolemia and depression? Behavioral evidence from the LDLr−/− mouse experimental model
DF Engel, J Oliveira, JB Lopes, DB Santos, EL Moreira, M Farina, AL Rodrigues, PS Brocardo, AF de Bem |
Behavioural Brain Research | 2016 |
|
Adiponectin improves NF-κB-mediated inflammation and abates atherosclerosis progression in apolipoprotein E-deficient mice
X Wang, Q Chen, H Pu, Q Wei, M Duan, C Zhang, T Jiang, X Shou, J Zhang, Y Yang |
Lipids in Health and Disease | 2016 |
|
The application of transcriptomic data in the authentication of beef derived from contrasting production systems
T Sweeney, A Lejeune, AP Moloney, FJ Monahan, PM Gettigan, G Downey, SD Park, MT Ryan |
BMC Genomics | 2016 |
|
Interactive effects of C-reactive protein levels on the association between APOE variants and triglyceride levels in a Taiwanese population
S Wu, LA Hsu, MS Teng, JF Lin, HH Chou, MC Lee, YM Wu, CW Su, YL Ko |
Lipids in Health and Disease | 2016 |
|
TANGO1 and Mia2/cTAGE5 (TALI) cooperate to export bulky pre-chylomicrons/VLDLs from the endoplasmic reticulum
AJ Santos, C Nogueira, M Ortega-Bellido, V Malhotra |
The Journal of Cell Biology | 2016 |
|
Dietary intake of cod and scallop reduces atherosclerotic burden in female apolipoprotein E-deficient mice fed a Western-type high fat diet for 13 weeks
IJ Jensen, M Walquist, B Liaset, EO Elvevoll, KE Eilertsen |
Nutrition & Metabolism | 2016 |
|
Atherosclerosis Alters Loading-Induced Arterial Damage: Implications for Robotic Surgery
R Geenens, N Famaey, A Gijbels, S Verhelle, S Vinckier, JV Sloten, P Herijgers, AP Gadeau |
PloS one | 2016 |
|
Adenosine A3 Receptor: A promising therapeutic target in cardiovascular disease
Shamama Nishat, Luqman A Khan, Zafar M Ansari, Seemi F Basir |
Current cardiology reviews | 2016 |
|
Caspase-1 mediates hyperlipidemia-weakened progenitor cell vessel repair
Ya-Feng Li, Xiao Huang, Xinyuan Li, Ren Gong, Ying Yin, Jun Nelson, Erhe Gao, Hongyu Zhang, Nicholas E Hoffman, Steven R Houser, Muniswamy Madesh, Douglas G Tilley, Eric T Choi, Xiaohua Jiang, Cong-Xin Huang, Hong Wang, Xiao-Feng Yang |
Frontiers in bioscience : a journal and virtual library | 2016 |
|
Temporal shifts in clinical presentation and underlying mechanisms of atherosclerotic disease
G Pasterkamp, HM Ruijter, P Libby |
Nature Reviews Cardiology | 2016 |
|
Imaging in Medical Diagnosis and Therapy: Preclinical Imaging, Therapy, and Applications
A Kalinowska, L Dobrucki |
Imaging in Medical Diagnosis and Therapy: Preclinical Imaging, Therapy, and Applications | 2016 |
|
Low-Density Lipoprotein Receptor Contributes to β-Carotene Uptake in the Maternal Liver
V Shete, B Costabile, YK Kim, L Quadro |
Nutrients | 2016 |
|
[ 18 F]FDG Uptake in the Aortic Wall Smooth Muscle of Atherosclerotic Plaques in the Simian Atherosclerosis Model
T Iwaki, H Mizuma, K Hokamura, H Onoe, K Umemura |
BioMed Research International | 2016 |
|
Chronic vitamin A-enriched diet feeding regulates hypercholesterolaemia through transcriptional regulation of reverse cholesterol transport pathway genes in obese rat model of WNIN/GR-Ob strain
SM Jeyakumar, A Sheril, A Vajreswari |
The Indian journal of medical research | 2016 |
|
Non-alcoholic steatohepatitis-associated hepatic fibrosis and hepatocellular carcinoma in a combined mouse model of genetic modification and dietary challenge: Mouse model of non-alcoholic steatohepatitis
Y Amano, F Shimizu, H Yasuno, A Harada, S Tsuchiya, O Isono, H Nagabukuro, R Tozawa |
Hepatology Research | 2016 |
|
Alzheimer's Disease Genetic Risk Factor APOE-ε4 Also Affects Normal Brain Function
Amanda M Di Battista, Nicolette M Heinsinger, G William Rebeck |
Current Alzheimer research | 2016 |
|
Mouse Models of Vascular Diseases
M Sata |
2016 | |
|
Apoptotic cells trigger a new membrane-initiated pathway to increase ABCA1
Aaron Fond, Chang Sup Lee, Ira Schulman, Robert Kiss, Kodi Ravichandran |
Journal of Clinical Investigation | 2015 |
|
The cholesterol transporter ABCG1 links cholesterol homeostasis and tumour immunity
D Sag, C Cekic, R Wu, J Linden, CC Hedrick |
Nature Communications | 2015 |
|
Imaging of Small Animal Peripheral Artery Disease Models: Recent Advancements and Translational Potential
J Lin, E Phillips, TA Riggins, G Sangha, S Chakraborty, J Lee, R Lycke, C Hernandez, A Soepriatna, B Thorne, A Yrineo, C Goergen |
International journal of molecular sciences | 2015 |
|
LDL Receptor-Related Protein-1 (LRP1) Regulates Cholesterol Accumulation in Macrophages
AP Lillis, SC Muratoglu, DT Au, M Migliorini, MJ Lee, SK Fried, I Mikhailenko, DK Strickland, P Aspichueta |
PloS one | 2015 |
|
Role of Nrf2 in the pathogenesis of atherosclerosis
J Mimura, K Itoh |
Free radical biology & medicine | 2015 |
|
Genetic Architecture of Atherosclerosis in Mice: A Systems Genetics Analysis of Common Inbred Strains
BJ Bennett, RC Davis, M Civelek, L Orozco, J Wu, H Qi, C Pan, RR Packard, E Eskin, M Yan, T Kirchgessner, Z Wang, X Li, JC Gregory, SL Hazen, PS Gargalovic, AJ Lusis, GS Barsh |
PLoS genetics | 2015 |
|
Animal Models of Diabetic Macrovascular Complications: Key Players in the Development of New Therapeutic Approaches
SE Heinonen, G Genové, E Bengtsson, T Hübschle, L Åkesson, K Hiss, A Benardeau, S Ylä-Herttuala, AC Jönsson-Rylander, MF Gomez |
Journal of Diabetes Research | 2015 |
|
Hypercholesterolemia, low density lipoprotein receptor and proprotein convertase subtilisin/kexin-type 9
Hong-Mei Gu, Da-Wei Zhang |
Journal of Biomedical Research | 2015 |
|
Phage-Display-Guided Nanocarrier Targeting to Atheroprone Vasculature
LH Hofmeister, SH Lee, AE Norlander, KR Montaniel, W Chen, DG Harrison, HJ Sung |
ACS Nano | 2015 |
|
Alteration of actin dependent signaling pathways associated with membrane microdomains in hyperlipidemia
VI Suica, E Uyy, RM Boteanu, L Ivan, F Antohe |
Proteome Science | 2015 |
|
Beyond vascular inflammation—recent advances in understanding atherosclerosis
D Wolf, A Zirlik, K Ley |
Cellular and Molecular Life Sciences | 2015 |
|
Potential for Dietary -3 Fatty Acids to Prevent Nonalcoholic Fatty Liver Disease and Reduce the Risk of Primary Liver Cancer
DB Jump, CM Depner, S Tripathy, KA Lytle |
Advances in nutrition (Bethesda, Md.) | 2015 |
|
Opposing effects of Apoe / Apoa1 double deletion on amyloid-β pathology and cognitive performance in APP mice
NF Fitz, V Tapias, AA Cronican, EL Castranio, M Saleem, AY Carter, M Lefterova, I Lefterov, R Koldamova |
Brain | 2015 |
|
IRF5 Deficiency Ameliorates Lupus but Promotes Atherosclerosis and Metabolic Dysfunction in a Mouse Model of Lupus-Associated Atherosclerosis
AA Watkins, K Yasuda, GE Wilson, T Aprahamian, Y Xie, E Maganto-Garcia, P Shukla, L Oberlander, B Laskow, H Menn-Josephy, Y Wu, P Duffau, SK Fried, AH Lichtman, RG Bonegio, IR Rifkin |
Journal of immunology (Baltimore, Md. : 1950) | 2015 |
|
Hyperlipidemia Promotes Anti-Donor Th17 Responses That Accelerate Allograft Rejection: Hyperlipidemia and Rejection by Th17 Cells
J Yuan, J Bagley, J Iacomini |
American Journal of Transplantation | 2015 |
|
Low-Density Lipoprotein Receptor-Related Protein 6 (LRP6) Is a Novel Nutritional Therapeutic Target for Hyperlipidemia, Non-Alcoholic Fatty Liver Disease, and Atherosclerosis
G Go |
Nutrients | 2015 |
|
Nanoparticle-Mediated Expression of a Wnt Pathway Inhibitor Ameliorates Ocular Neovascularization
Z Wang, R Cheng, K Lee, P Tyagi, L Ding, UB Kompella, J Chen, X Xu, J Ma |
Arteriosclerosis, thrombosis, and vascular biology | 2015 |
|
Voluntary Exercise Decreases Atherosclerosis in Nephrectomised ApoE Knockout Mice
CM Shing, RG Fassett, JM Peake, JS Coombes, Q Sun |
PloS one | 2015 |
|
Development and rescue of human familial hypercholesterolaemia in a xenograft mouse model
B Bissig-Choisat, L Wang, X Legras, PK Saha, L Chen, P Bell, FP Pankowicz, MC Hill, M Barzi, CK Leyton, HC Leung, RL Kruse, RW Himes, JA Goss, JM Wilson, L Chan, WR Lagor, KD Bissig |
Nature Communications | 2015 |
|
Acute perioperative stress-induced increase of plaque volume and vulnerability in apolipoprotein E-deficient mice is amenable to statin treatment and IL-6-inhibition
H Janssen, CS Wagner, P Demmer, S Callies, G Solter, HL Kouzhani, N Hu, H Schuett, UJ Tietge, G Warnecke, J Larmann, G Theilmeier |
Disease models & mechanisms | 2015 |
|
RIP140 contributes to foam cell formation and atherosclerosis by regulating cholesterol homeostasis in macrophages
YW Lin, PS Liu, N Adhikari, JL Hall, LN Wei |
Journal of Molecular and Cellular Cardiology | 2015 |
|
Genome-wide identification of microRNAs regulating cholesterol and triglyceride homeostasis
A Wagschal, SH Najafi-Shoushtari, L Wang, L Goedeke, S Sinha, AS deLemos, JC Black, CM Ramírez, Y Li, R Tewhey, I Hatoum, N Shah, Y Lu, F Kristo, N Psychogios, V Vrbanac, YC Lu, T Hla, R Cabo, JS Tsang, E Schadt, PC Sabeti, S Kathiresan, DE Cohen, J Whetstine, RT Chung, C Fernández-Hernando, LM Kaplan, A Bernards, RE Gerszten, AM Näär |
Nature Medicine | 2015 |
|
Hypercholesterolemia Induced Immune Response and Inflammation on Progression of Atherosclerosis in Apob tm2Sgy Ldlr tm1Her/J Mice
LN Rao, T Ponnusamy, S Philip, R Mukhopadhyay, VV Kakkar, L Mundkur |
Lipids | 2015 |
|
Brown fat activation reduces hypercholesterolaemia and protects from atherosclerosis development
JF Berbée, MR Boon, PP Khedoe, A Bartelt, C Schlein, A Worthmann, S Kooijman, G Hoeke, IM Mol, C John, C Jung, N Vazirpanah, LP Brouwers, PL Gordts, JD Esko, PS Hiemstra, LM Havekes, L Scheja, J Heeren, PC Rensen |
Nature Communications | 2015 |
|
Animal models of coronary heart disease.
Liao J, Huang W, Liu G |
Journal of Biomedical Research | 2015 |
|
Cholesterol metabolism and homeostasis in the brain
J Zhang, Q Liu |
Protein & Cell | 2015 |
|
Genetic therapies to lower cholesterol
B Khoo |
Vascular Pharmacology | 2015 |
|
Cholesterol-Induced Hepatic Inflammation Does Not Underlie the Predisposition to Insulin Resistance in Dyslipidemic Female LDL Receptor Knockout Mice
N Gruben, A Funke, NJ Kloosterhuis, M Schreurs, F Sheedfar, R Havinga, SM Houten, R Shiri-Sverdlov, B de Sluis, JA Kuivenhoven, DP Koonen, MH Hofker |
Journal of Diabetes Research | 2015 |
|
Microsomal Transfer Protein Inhibitors, New Approach for Treatment of Familial Hypercholesterolemia, Review of the Literature, Original Findings, and Clinical Significance
G Kolovou, I Vasiliadis, N Gontoras, V Kolovou, G Hatzigeorgiou |
Cardiovascular Therapeutics | 2015 |
|
Hypercholesterolemia and neurodegeneration. Comparison of hippocampal phenotypes in LDLr knockout and APPswe/PS1dE9 mice
M Ettcheto, D Petrov, I Pedrós, L Lemos, M Pallàs, M Alegret, JC Laguna, J Folch, A Camins |
Experimental Gerontology | 2015 |
|
Metabonomic Changes Associated with Atherosclerosis Progression for LDLR –/– Mice
D Li, L Zhang, F Dong, Y Liu, N Li, H Li, H Lei, F Hao, Y Wang, Y Zhu, H Tang |
Journal of Proteome Research | 2015 |
|
Apolipoprotein B48, the Structural Component of Chylomicrons, Is Sufficient to Antagonize Staphylococcus aureus Quorum-Sensing
BO Elmore, KD Triplett, PR Hall, MJ Horsburgh |
PloS one | 2015 |
|
Animal Models in Cardiovascular Research: Hypertension and Atherosclerosis
XF Leong, CY Ng, K Jaarin |
BioMed Research International | 2015 |
|
Hypercholesterolemia and ApoE deficiency result in severe infection with Lyme disease and relapsing-fever Borrelia
A Toledo, JD Monzón, JL Coleman, JC Garcia-Monco, JL Benach |
Proceedings of the National Academy of Sciences | 2015 |
|
Deficiency of cystathionine gamma-lyase and hepatic cholesterol accumulation during mouse fatty liver development
S Mani, H Li, G Yang, L Wu, R Wang |
Science Bulletin | 2015 |
|
IAVPGEVA, IAVPTGVA, and LPYP, three peptides from soy glycinin, modulate cholesterol metabolism in HepG2 cells through the activation of the LDLR-SREBP2 pathway
C Lammi, C Zanoni, A Arnoldi |
Journal of Functional Foods | 2015 |
|
Prospect and progress of gene therapy in treating atherosclerosis
AM Kivelä, J Huusko, S Ylä-Herttuala |
Expert Opinion on Biological Therapy | 2015 |
|
Discovery and Optimization of Imidazopyridine-based Inhibitors of Diacylglycerol Acyltransferase 2 (DGAT2)
K Futatsugi, DW Kung, ST Orr, S Cabral, D Hepworth, G Aspnes, SJ Bader, J Bian, M Boehm, PA Carpino, S Coffey, MS Dowling, M Herr, W Jiao, SY Lavergne, Q Li, RW Clark, D Erion, K Kou, K Lee, BA Pabst, SM Perez, J Purkal, CC Jorgensen, TC Goosen, JR Gosset, M Niosi, JC Pettersen, JA Pfefferkorn, K Ahn, B Goodwin |
Journal of Medicinal Chemistry | 2015 |
|
Atherosclerosis: Risks, Mechanisms, and Therapies
HJ Pownall, C Rosales, BK Gillard, AM Gotto |
Atherosclerosis: Risks, Mechanisms, and Therapies | 2015 |
|
PCSK9 deficiency unmasks a sex- and tissue-specific subcellular distribution of the LDL and VLDL receptors in mice
A Roubtsova, A Chamberland, J Marcinkiewicz, R Essalmani, A Fazel, JJ Bergeron, NG Seidah, A Prat |
Journal of lipid research | 2015 |
|
Weekly Treatment of 2-Hydroxypropyl-β-cyclodextrin Improves Intracellular Cholesterol Levels in LDL Receptor Knockout Mice
S Walenbergh, T Houben, T Hendrikx, M Jeurissen, P Gorp, N Vaes, S Damink, F Verheyen, G Koek, D Lütjohann, A Grebe, E Latz, R Shiri-Sverdlov |
International journal of molecular sciences | 2015 |
|
Targets to treat metabolic syndrome in polycystic ovary syndrome
S Mahalingaiah, E Diamanti-Kandarakis |
Expert Opinion on Therapeutic Targets | 2015 |
|
The epigenetic processes of meiosis in male mice are broadly affected by the widely used herbicide atrazine
A Gely-Pernot, C Hao, E Becker, I Stuparevic, C Kervarrec, F Chalmel, M Primig, B Jégou, F Smagulova |
BMC Genomics | 2015 |
|
Effects of murine norovirus on atherosclerosis in ldlr(-/-) mice depends on the timing of infection
Jisun Paik, Fiona Kwok, Audrey Seamons, Thea Brabb, Jinkyu Kim, Brittany Sullivan, Charlie Hsu, Kevin D O'Brien, Lillian Maggio-Price |
Comparative medicine | 2015 |
|
Effects of Murine Norovirus on Atherosclerosis in Ldlr–/– Mice Depends on the Timing of Infection
Jisun Paik, Fiona Kwok, Audrey Seamons, Thea Brabb, Jinkyu Kim, Brittany Sullivan, Charlie Hsu, Kevin D O'Brien, Lillian Maggio-Price |
Comparative medicine | 2015 |
|
Targeting SREBPs for treatment of the metabolic syndrome
SM Soyal, C Nofziger, S Dossena, M Paulmichl, W Patsch |
Trends in Pharmacological Sciences | 2015 |
|
Investigation of RNA interference suppression of matrix metalloproteinase-9 in mouse model of atherosclerosis
Zhe-Xiu Jin, Qiang Xiong, Fang Jia, Chun-Ling Sun, Hong-Tao Zhu, Fu-Sheng Ke |
International journal of clinical and experimental medicine | 2015 |
|
The immunomodulatory parasitic worm product ES-62 reduces lupus-associated accelerated atherosclerosis in a mouse model
TR Aprahamian, X Zhong, S Amir, CJ Binder, LK Chiang, L Al-Riyami, R Gharakhanian, MM Harnett, W Harnett, IR Rifkin |
International Journal for Parasitology | 2015 |
|
Genetic Dissection of Tissue-Specific Apolipoprotein E Function for Hypercholesterolemia and Diet-Induced Obesity
T Wagner, A Bartelt, C Schlein, J Heeren, M Oberer |
PloS one | 2015 |
|
Novel Animal Models of Atherosclerosis
A Rezvan, S Sur, H Jo |
Biomedical Engineering Letters | 2015 |
|
Absence of Elovl6 attenuates steatohepatitis but promotes gallstone formation in a lithogenic diet-fed Ldlr−/− mouse model
M Kuba, T Matsuzaka, R Matsumori, R Saito, N Kaga, H Taka, K Ikehata, N Okada, T Kikuchi, H Ohno, S Han, Y Takeuchi, K Kobayashi, H Iwasaki, S Yatoh, H Suzuki, H Sone, N Yahagi, Y Arakawa, T Fujimura, Y Nakagawa, N Yamada, H Shimano |
Scientific Reports | 2015 |
|
The role of a murine transplantation model of atherosclerosis regression in drug discovery
Jonathan E Feig, John S Quick, Edward A Fisher |
Current opinion in investigational drugs (London, England : 2000) | 2015 |
|
microRNA-379 couples glucocorticoid hormones to dysfunctional lipid homeostasis
RM de Guia, AJ Rose, A Sommerfeld, O Seibert, D Strzoda, A Zota, Y Feuchter, A Krones-Herzig, T Sijmonsma, M Kirilov, C Sticht, N Gretz, G Dallinga-Thie, S Diederichs, N Kloting, M Bluher, MB Diaz, S Herzig |
The EMBO Journal | 2014 |
|
A Computational Model for the Analysis of Lipoprotein Distributions in the Mouse: Translating FPLC Profiles to Lipoprotein Metabolism
FL Sips, CA Tiemann, MH Oosterveer, AK Groen, PA Hilbers, NA van Riel |
PLoS computational biology | 2014 |
|
Epigenome-Guided Analysis of the Transcriptome of Plaque Macrophages during Atherosclerosis Regression Reveals Activation of the Wnt Signaling Pathway
SA Ramsey, Y Vengrenyuk, P Menon, I Podolsky, JE Feig, A Aderem, EA Fisher, ES Gold, DJ Rader |
PLoS genetics | 2014 |
|
The role of sphingosine-1-phosphate in endothelial barrier function
BA Wilkerson, KM Argraves |
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids | 2014 |
|
Hidden Disease Susceptibility and Sexual Dimorphism in the Heterozygous Knockout of Cyp51 from Cholesterol Synthesis
M Lewinska, P Juvan, M Perse, J Jeruc, S Kos, G Lorbek, Z Urlep, R Keber, S Horvat, D Rozman, JM Lobaccaro |
PloS one | 2014 |
|
Alginic acid cell entrapment: a novel method for measuring in vivo macrophage cholesterol homeostasis
TJ Sontag, B Chellan, CV Bhanvadia, GS Getz, CA Reardon |
Journal of lipid research | 2014 |
|
Genetic Alterations Affecting Cholesterol Metabolism and Human Fertility
AM DeAngelis, M Roy-O'Reilly, A Rodriguez |
Biology of reproduction | 2014 |
|
The adipokine Retnla modulates cholesterol homeostasis in hyperlipidemic mice
MR Lee, C Lim, YH Lee, JG Park, SK Sonn, MN Lee, IH Jung, SJ Jeong, S Jeon, M Lee, KS Oh, Y Yang, JB Kim, HS Choi, W Jeong, TS Jeong, WK Yoon, HC Kim, JH Choi, GT Oh |
Nature Communications | 2014 |
|
Deletion of ELOVL6 blocks the synthesis of oleic acid but does not prevent the development of fatty liver or insulin resistance
YA Moon, CR Ochoa, MA Mitsche, RE Hammer, JD Horton |
Journal of lipid research | 2014 |
|
H1-antihistamines exacerbate high-fat diet-induced hepatic steatosis in wild-type but not in apolipoprotein E knockout mice
VV Raveendran, KM Kassel, DD Smith, JP Luyendyk, KJ Williams, R Cherian, GA Reed, CA Flynn, IL Csanaky, AL Lickteig, MJ Pratt-Hyatt, CD Klaassen, KN Dileepan |
AJP Gastrointestinal and Liver Physiology | 2014 |
|
Adiponectin expression and the cardioprotective role of the vitamin D receptor activator paricalcitol and the angiotensin converting enzyme inhibitor enalapril in ApoE-deficient mice
E Suarez-Martinez, K Husain, L Ferder |
Therapeutic advances in cardiovascular disease | 2014 |
|
High density lipoprotein metabolism in low density lipoprotein receptor-deficient mice
F Rinninger, M Heine, R Singaraja, M Hayden, M Brundert, R Ramakrishnan, J Heeren |
Journal of lipid research | 2014 |
|
In vitro models of aortic valve calcification: solidifying a system
MA Bowler, WD Merryman |
Cardiovascular Pathology | 2014 |
|
Targeted Reduction of Vascular Msx1 and Msx2 Mitigates Arteriosclerotic Calcification and Aortic Stiffness in LDLR-Deficient Mice Fed Diabetogenic Diets
SL Cheng, A Behrmann, JS Shao, B Ramachandran, K Krchma, YB Arredondo, A Kovacs, M Mead, R Maxson, DA Towler |
Diabetes | 2014 |
|
Delivery of negatively charged liposomes into the atherosclerotic plaque of apolipoprotein E-deficient mouse aortic tissue
S Zhaorigetu, C Rodriguez-Aguayo, AK Sood, G Lopez-Berestein, BL Walton |
Journal of Liposome Research | 2014 |
|
Macrophage deficiency of Akt2 reduces atherosclerosis in Ldlr null mice
VR Babaev, KE Hebron, CB Wiese, CL Toth, L Ding, Y Zhang, JM May, S Fazio, KC Vickers, MF Linton |
Journal of lipid research | 2014 |
|
Genetic network identifies novel pathways contributing to atherosclerosis susceptibility in the innominate artery
J Albright, PM Quizon, AJ Lusis, BJ Bennett |
BMC Medical Genomics | 2014 |
|
The Sirt1 activator SRT3025 provides atheroprotection in Apoe-/- mice by reducing hepatic Pcsk9 secretion and enhancing Ldlr expression
MX Miranda, LJ van Tits, C Lohmann, T Arsiwala, S Winnik, A Tailleux, S Stein, AP Gomes, V Suri, JL Ellis, TA Lutz, MO Hottiger, DA Sinclair, J Auwerx, K Schoonjans, B Staels, TF Luscher, CM Matter |
European Heart Journal | 2014 |
|
Inhibiting DNA Methylation by 5-Aza-2′-deoxycytidine Ameliorates Atherosclerosis Through Suppressing Macrophage Inflammation
Q Cao, X Wang, L Jia, AK Mondal, A Diallo, GA Hawkins, SK Das, JS Parks, L Yu, H Shi, H Shi, B Xue |
Endocrinology | 2014 |
|
Targeted Disruption of LDLR Causes Hypercholesterolemia and Atherosclerosis in Yucatan Miniature Pigs
BT Davis, XJ Wang, JA Rohret, JT Struzynski, EP Merricks, DA Bellinger, FA Rohret, TC Nichols, CS Rogers, Y Zhang |
PloS one | 2014 |
|
Recent advances in physiological lipoprotein metabolism
I Ramasamy |
Clinical Chemistry and Laboratory Medicine | 2014 |
|
Regression of Atherosclerosis: Insights from Animal and Clinical Studies
JE Feig |
Annals of Global Health | 2014 |
|
Impaired compensatory beta-cell function and growth in response to high-fat diet in LDL receptor knockout mice
RB Oliveira, CP Carvalho, CC Polo, GG Dorighello, AC Boschero, HC Oliveira, CB Collares-Buzato |
International Journal of Experimental Pathology | 2014 |
|
MicroRNA-223 coordinates cholesterol homeostasis
KC Vickers, SR Landstreet, MG Levin, BM Shoucri, CL Toth, RC Taylor, BT Palmisano, F Tabet, HL Cui, KA Rye, P Sethupathy, AT Remaley |
Proceedings of the National Academy of Sciences | 2014 |
|
Epidermal growth factor receptor plays a role in the regulation of liver and plasma lipid levels in adult male mice
LA Scheving, X Zhang, OA Garcia, RF Wang, MC Stevenson, DW Threadgill, WE Russell |
AJP Gastrointestinal and Liver Physiology | 2014 |
|
Oxidized LDL-induced angiogenesis involves sphingosine 1-phosphate: prevention by anti-S1P antibody: Anti-S1P mAb inhibits oxLDL-induced angiogenesis
C Camaré, M Trayssac, B Garmy-Susini, E Mucher, R Sabbadini, R Salvayre, A Negre-Salvayre |
British Journal of Pharmacology | 2014 |
|
Nanotoxicity overview: nano-threat to susceptible populations
Y Li, Y Zhang, B Yan |
International journal of molecular sciences | 2014 |
|
Early Onset Intrauterine Growth Restriction in a Mouse Model of Gestational Hypercholesterolemia and Atherosclerosis
D Busso, L Mascareño, F Salas, L Berkowitz, N Santander, A Quiroz, L Amigo, G Valdés, A Rigotti |
BioMed Research International | 2014 |
|
A Journey in Science: Medical Scientist in Translation
Hansson GK |
Molecular Medicine | 2014 |
|
Apolipoprotein E–low density lipoprotein receptor interaction affects spatial memory retention and brain ApoE levels in an isoform-dependent manner
LA Johnson, RH Olsen, LS Merkens, A DeBarber, RD Steiner, PM Sullivan, N Maeda, J Raber |
Neurobiology of Disease | 2014 |
|
Changes in arterial function in a mouse model of human familial hypercholesterolaemia
O Brinkmann, K Schmerbach, UJ Tietge, T Dietrich, H Guski, D Linz, H Kühn, A Patzak, K Wilfert |
Acta physiologica (Oxford, England) | 2014 |
|
Long-term vitamin E supplementation reduces atherosclerosis and mortality in Ldlr−/− mice, but not when fed Western style diet
M Meydani, P Kwan, M Band, A Knight, W Guo, J Goutis, J Ordovas |
Atherosclerosis | 2014 |
|
Assessing the ceRNA Hypothesis with Quantitative Measurements of miRNA and Target Abundance
R Denzler, V Agarwal, J Stefano, DP Bartel, M Stoffel |
Molecular Cell | 2014 |
|
Consumption of whole grains and legumes modulates the genetic effect of the APOA5 -1131C variant on changes in triglyceride and apolipoprotein A-V concentrations in patients with impaired fasting glucose or newly diagnosed type 2 diabetes
R Kang, M Kim, JS Chae, SH Lee, JH Lee |
Trials | 2014 |
|
Altered vascular smooth muscle function in the ApoE knockout mouse during the progression of atherosclerosis
MA Ewart, S Kennedy, D Macmillan, AL Raja, IM Watt, S Currie |
Atherosclerosis | 2014 |
|
Atherosclerosis affects calcium signalling in endothelial cells from apolipoprotein E knockout mice before plaque formation
C Prendergast, J Quayle, T Burdyga, S Wray |
Cell Calcium | 2014 |
|
Mecanismos básicos. Absorción y excreción de colesterol y otros esteroles
MC Pujol |
Clínica e Investigación en Arteriosclerosis | 2014 |
|
Animal models of C-reactive protein
M Torzewski, AB Waqar, J Fan |
Mediators of Inflammation | 2014 |
|
Impact of daily Chlorella consumption on serum lipid and carotenoid profiles in mildly hypercholesterolemic adults: a double-blinded, randomized, placebo-controlled study
NH Ryu, Y Lim, JE Park, J Kim, JY Kim, SW Kwon, O Kwon |
Nutrition Journal | 2014 |
|
Mining the genome for lipid genes
JA Kuivenhoven, RA Hegele |
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease | 2014 |
|
Primary genetic investigation of a hyperlipidemia model: molecular characteristics and variants of the apolipoprotein e gene in mongolian gerbil
Y Liu, J Wu, Q Shi, H Guo, H Ying, N Xu |
BioMed Research International | 2014 |
|
APOE*3Leiden.CETP transgenic mice as model for pharmaceutical treatment of the metabolic syndrome
AM van Hoek, JW van der Hoorn, AC Maas, RM van Hoogen, A Nieuwkoop, S Droog, EH Offerman, EJ Pieterman, LM Havekes, HM Princen |
Diabetes Obesity and Metabolism | 2014 |
|
The role of heat shock proteins in atherosclerosis
G Wick, B Jakic, M Buszko, MC Wick, C Grundtman |
Nature Reviews Cardiology | 2014 |
|
Impact of Age-Dependent Adventitia Inflammation on Structural Alteration of Abdominal Aorta in Hyperlipidemic Mice
S Sakamoto, T Tsuruda, K Hatakeyama, T Imamura, Y Asada, K Kitamura, PM Bauer |
PloS one | 2014 |
|
Why AMD is a disease of ageing and not of development: mechanisms and insights
K Sharma, NK Sharma, A Anand |
Frontiers in aging neuroscience | 2014 |
|
Insights into Hepatopancreatic Functions for Nutrition Metabolism and Ovarian Development in the Crab Portunus trituberculatus: Gene Discovery in the Comparative Transcriptome of Different Hepatopancreas Stages
W Wang, X Wu, Z Liu, H Zheng, Y Cheng, E Buratti |
PloS one | 2014 |
|
Patterned Substrates of Nano-Graphene Oxide Mediating Highly Localized and Efficient Gene Delivery
K Li, L Feng, J Shen, Q Zhang, Z Liu, ST Lee, J Liu |
ACS Applied Materials & Interfaces | 2014 |
|
Cholesterol-induced hepatic inflammation does not contribute to the development of insulin resistance in male LDL receptor knockout mice
A Funke, M Schreurs, M Aparicio-Vergara, F Sheedfar, N Gruben, NJ Kloosterhuis, R Shiri-Sverdlov, AK Groen, B de Sluis, MH Hofker, DP Koonen |
Atherosclerosis | 2014 |
|
Posttranslational modifications of histone deacetylases: Implications for cardiovascular diseases
GH Eom, H Kook |
Pharmacology & Therapeutics | 2014 |
|
Hyperlipidemia compromises homing efficiency of systemically transplanted BMSCs and inhibits bone regeneration
QC Xu, PJ Hao, XB Yu, SL Chen, MJ Yu, J Zhang, PS Yang |
International journal of clinical and experimental pathology | 2014 |
|
Atherosclerosis differentially affects calcium signalling in endothelial cells from aortic arch and thoracic aorta in Apolipoprotein E knockout mice
C Prendergast, J Quayle, T Burdyga, S Wray |
Physiological Reports | 2014 |
|
Acetate Dependence of Tumors
SA Comerford, Z Huang, X Du, Y Wang, L Cai, AK Witkiewicz, H Walters, MN Tantawy, A Fu, HC Manning, JD Horton, RE Hammer, SL McKnight, BP Tu |
Cell | 2014 |
|
LDL receptor knock-out mice show impaired spatial cognition with hippocampal vulnerability to apoptosis and deficits in synapses
S Wang, Y Huang, Y Yuan, W Xia, P Wang, R Huang |
Lipids in Health and Disease | 2014 |
|
A mutation in Ampd2 is associated with nephrotic syndrome and hypercholesterolemia in mice
J Helmering, T Juan, C Li, M Chhoa, W Baron, T Gyuris, WG Richards, JR Turk, J Lawrence, PA Cosgrove, J Busby, K Kim, SA Kaufman, C Cummings, G Carlson, MM Véniant, DJ Lloyd |
Lipids in Health and Disease | 2014 |
|
Peptide-Based Anti-PCSK9 Vaccines - An Approach for Long-Term LDLc Management
G Galabova, S Brunner, G Winsauer, C Juno, B Wanko, A Mairhofer, P Lührs, A Schneeberger, A Bonin, F Mattner, W Schmidt, G Staffler, F Pappalardo |
PloS one | 2014 |
|
Improved Derivation Efficiency and Pluripotency of Stem Cells from the Refractory Inbred C57BL/6 Mouse Strain by Small Molecules
CJ Lin, T Amano, Y Tang, X Tian, R Johnson |
PloS one | 2014 |
|
Reducing Elevated Plasma LDL Cholesterol: The Central Role of the LDL Receptor
J Vincent |
Clinical Pharmacology & Therapeutics | 2014 |
|
An ex-vivo model for evaluating bioenergetics in aortic rings
KP Feeley, DG Westbrook, AW Bray, SW Ballinger |
Redox Biology | 2014 |
|
Effects of intra-abdominal sepsis on atherosclerosis in mice
AM Kaynar, S Yende, L Zhu, DR Frederick, R Chambers, CL Burton, M Carter, DB Stolz, B Agostini, AD Gregory, S Nagarajan, SD Shapiro, DC Angus |
Critical Care | 2014 |
|
Increased sensitivity of Apolipoprotein E knockout mice to swainsonine dependent immunomodulation
DW Scott, LL Black, MO Vallejo, JH Kabarowski, RP Patel |
Immunobiology | 2014 |
|
Receptor heterodimerization as a novel mechanism for the regulation of Wnt/ -catenin signaling
K Lee, Y Shin, R Cheng, K Park, Y Hu, J McBride, X He, Y Takahashi, J Ma |
Journal of cell science | 2014 |
|
Lupin Peptides Lower Low-Density Lipoprotein (LDL) Cholesterol through an Up-regulation of the LDL Receptor/Sterol Regulatory Element Binding Protein 2 (SREBP2) Pathway at HepG2 Cell Line
C Lammi, C Zanoni, GM Scigliuolo, A D’Amato, A Arnoldi |
Journal of Agricultural and Food Chemistry | 2014 |
|
Prolactin receptor antagonism uncouples lipids from atherosclerosis susceptibility
RJ van der Sluis, T Aardweg, AQ Reuwer, MT Twickler, F Boutillon, MV Eck, V Goffin, M Hoekstra |
Journal of Endocrinology | 2014 |
|
Direct sequencing for comprehensive screening of LDLR genetic polymorphisms among five ethnic populations
JH Kim, HS Cheong, LH Kim, HJ Shin, HS Na, MW Chung, HD Shin |
Genes & Genomics | 2014 |
|
Vascular hypercontractility and endothelial dysfunction before development of atherosclerosis in moderate dyslipidemia: role for nitric oxide and interleukin-6
Vanessa Cavieres, Karla Valdes, Brayan Moreno, Rodrigo Moore-Carrasco, Daniel R Gonzalez |
American Journal of Cardiovascular Disease | 2014 |
|
Accelerating the Pace of Atherosclerosis Research
A Daugherty, I Tabas, DJ Rader |
Arteriosclerosis, thrombosis, and vascular biology | 2014 |
|
Neuroprotective roles of pituitary adenylate cyclase-activating polypeptide in neurodegenerative diseases
EH Lee, SR Seo |
BMB Reports | 2014 |
|
Effects of the Absence of Apolipoprotein E on Lipoproteins, Neurocognitive Function, and Retinal Function
AC Mak, CR Pullinger, LF Tang, JS Wong, RC Deo, JM Schwarz, A Gugliucci, I Movsesyan, BY Ishida, C Chu, A Poon, P Kim, EO Stock, EJ Schaefer, BF Asztalos, JM Castellano, T Wyss-Coray, JL Duncan, BL Miller, JP Kane, PY Kwok, MJ Malloy |
JAMA NEUROL | 2014 |
|
A Computational Model for the Analysis of Lipoprotein Distributions in the Mouse: Translating FPLC Profiles to Lipoprotein Metabolism
FL Sips, CA Tiemann, MH Oosterveer, AK Groen, PA Hilbers, NA van Riel, V Hatzimanikatis |
PLoS computational biology | 2014 |
|
Diet-induced (epigenetic) changes in bone marrow augment atherosclerosis
E Kampen, A Jaminon, TJ van Berkel, MV Eck |
Journal of leukocyte biology | 2014 |
|
Apolipoproteins E and AV Mediate Lipoprotein Clearance by Hepatic Proteoglycans
Jon C. Gonzales, Philip L.S.M. Gordts, Erin M. Foley, Jeffrey D. Esko |
Journal of Clinical Investigation | 2013 |
|
A major role for RCAN1 in atherosclerosis progression
N Méndez-Barbero, V Esteban, S Villahoz, A Escolano, K Urso, A Alfranca, C Rodríguez, SA Sánchez, T Osawa, V Andrés, J Martínez-González, T Minami, JM Redondo, MR Campanero |
EMBO Molecular Medicine | 2013 |
|
Identification of apolipoprotein D as a cardioprotective gene using a mouse model of lethal atherosclerotic coronary artery disease
K Tsukamoto, DR Mani, J Shi, S Zhang, DE Haagensen, F Otsuka, J Guan, JD Smith, W Weng, R Liao, FD Kolodgie, R Virmani, M Krieger |
Proceedings of the National Academy of Sciences | 2013 |
|
Targeting GGTase-I activates RHOA, increases macrophage reverse cholesterol transport, and reduces atherosclerosis in mice
OM Khan, MK Akula, K Skålen, C Karlsson, M Ståhlman, SG Young, J Borén, MO Bergo |
Circulation | 2013 |
|
Immunological aspects of atherosclerosis
S Garrido-Urbani, M Meguenani, F Montecucco, BA Imhof |
Seminars in Immunopathology | 2013 |
|
Cadherin-11 Expression Patterns in Heart Valves Associate with Key Functions during Embryonic Cushion Formation, Valve Maturation and Calcification
J Zhou, C Bowen, G Lu, C Knapp, A Recknagel, RA Norris, JT Butcher |
2013 | |
|
Mouse models to study the effect of cardiovascular risk factors on brain structure and cognition
DI Bink, K Ritz, E Aronica, L der Weerd, MJ Daemen |
Journal of Cerebral Blood Flow & Metabolism | 2013 |
|
Doinseunggitang ameliorates endothelial dysfunction in diabetic atherosclerosis
JJ Yoon, YJ Lee, OJ Park, SM Lee, YP Lee, NG Cho, DG Kang, HS Lee |
Evidence-Based Complementary and Alternative Medicine | 2013 |
|
Thiazolidinediones partially reverse the metabolic disturbances observed in Bscl2/seipin-deficient mice
X Prieur, L Dollet, M Takahashi, M Nemani, B Pillot, CL May, C Mounier, H Takigawa-Imamura, D Zelenika, F Matsuda, B Fève, J Capeau, M Lathrop, P Costet, B Cariou, J Magré |
Diabetologia | 2013 |
|
Adaptive Immunity and Atherosclerosis
AH Lichtman |
The American Journal of Pathology | 2013 |
|
Hypoxia in murine atherosclerotic plaques and its adverse effects on macrophages
S Parathath, Y Yang, S Mick, EA Fisher |
Trends in Cardiovascular Medicine | 2013 |
|
S-nitrosylation of ARH is required for LDL uptake by the LDL receptor
Z Zhao, S Pompey, H Dong, J Weng, R Garuti, P Michaely |
Journal of lipid research | 2013 |
|
Liver ABCA1 Deletion in LDLrKO Mice Does Not Impair Macrophage Reverse Cholesterol Transport or Exacerbate Atherogenesis
X Bi, X Zhu, M Duong, EY Boudyguina, MD Wilson, AK Gebre, JS Parks |
Arteriosclerosis, thrombosis, and vascular biology | 2013 |
|
The thyroid receptor modulator KB3495 reduces atherosclerosis independently of total cholesterol in the circulation in ApoE deficient mice
LM Mörk, S Rehnmark, P Davoodpour, GD Norata, L Larsson, MR Witt, J Malm, P Parini |
PloS one | 2013 |
|
A Novel Mathematical Model Detecting Early Individual Changes of Insulin Resistance
C Eberle, W Palinski, C Ament |
Diabetes Technology & Therapeutics | 2013 |
|
Hematopoietic G-protein-coupled receptor kinase 2 deficiency decreases atherosclerotic lesion formation in LDL receptor-knockout mice
JJ Otten, SC de Jager, A Kavelaars, T Seijkens, I Bot, E Wijnands, L Beckers, MM Westra, M Bot, M Busch, B Bermudez, TJ van Berkel, CJ Heijnen, EA Biessen |
The FASEB Journal | 2013 |
|
Echium Oil Reduces Plasma Triglycerides by Increasing Intravascular Lipolysis in apoB100-Only Low Density Lipoprotein (LDL) Receptor Knockout Mice
L Forrest, C Lough, S Chung, E Boudyguina, A Gebre, T Smith, P Colvin, J Parks |
Nutrients | 2013 |
|
Sphingolipid metabolism and obesity-induced inflammation
SC Kang, BR Kim, SY Lee, TS Park |
Frontiers in Endocrinology | 2013 |
|
Heterodimerization With the Prostacyclin Receptor Triggers Thromboxane Receptor Relocation to Lipid Rafts
S Ibrahim, A McCartney, N Markosyan, EM Smyth |
Arteriosclerosis, thrombosis, and vascular biology | 2013 |
|
Hyodeoxycholic acid improves HDL function and inhibits atherosclerotic lesion formation in LDLR-knockout mice
DM Shih, Z Shaposhnik, Y Meng, M Rosales, X Wang, J Wu, B Ratiner, F Zadini, G Zadini, AJ Lusis |
The FASEB Journal | 2013 |
|
Fortilin reduces apoptosis in macrophages and promotes atherosclerosis
D Pinkaew, RJ Le, Y Chen, M Eltorky, BB Teng, K Fujise |
American journal of physiology. Heart and circulatory physiology | 2013 |
|
Nrf2 and Cardiovascular Defense
R Howden |
Oxidative medicine and cellular longevity | 2013 |
|
Macrophages in atherosclerosis: a dynamic balance
KJ Moore, FJ Sheedy, EA Fisher |
Nature Reviews Immunology | 2013 |
|
Lipoproteins and Cardiovascular Disease
LA Freeman |
2013 | |
|
Lipoproteins and Cardiovascular Disease
LA Freeman |
2013 | |
|
Lipoproteins and Cardiovascular Disease
LA Freeman |
2013 | |
|
Paradoxical protection from atherosclerosis and thrombosis in a mouse model of sickle cell disease
H Wang, W Luo, J Wang, C Guo, SL Wolffe, J Wang, EB Sun, KN Bradley, AD Campbell, DT Eitzman |
British Journal of Haematology | 2013 |
|
Wound Regeneration and Repair
RG Gourdie, TA Myers |
Wound Regeneration and Repair | 2013 |
|
Wound Regeneration and Repair
RG Gourdie, TA Myers |
Wound Regeneration and Repair | 2013 |
|
Wound Regeneration and Repair
RG Gourdie, TA Myers |
Wound Regeneration and Repair | 2013 |
|
Wound Regeneration and Repair
RG Gourdie, TA Myers |
Wound Regeneration and Repair | 2013 |
|
Wound Regeneration and Repair
RG Gourdie, TA Myers |
Wound Regeneration and Repair | 2013 |
|
Wound Regeneration and Repair
RG Gourdie, TA Myers |
Wound Regeneration and Repair | 2013 |
|
Hyperlipidemia disrupts cerebrovascular reflexes and worsens ischemic perfusion defect
C Ayata, HK Shin, E Dileköz, DN Atochin, S Kashiwagi, K Eikermann-Haerter, PL Huang |
Journal of Cerebral Blood Flow & Metabolism | 2013 |
|
ILDR2: an endoplasmic reticulum resident molecule mediating hepatic lipid homeostasis
K Watanabe, E Watson, ML Cremona, EJ Millings, JH Lefkowitch, SG Fischer, CA LeDuc, RL Leibel |
PloS one | 2013 |
|
Genetically modified pigs to model human diseases
T Flisikowska, A Kind, A Schnieke |
Journal of Applied Genetics | 2013 |
|
Establishment of a novel murine model of ischemic cardiomyopathy with multiple diffuse coronary lesions
H Nakaoka, Y Nakagawa-Toyama, M Nishida, T Okada, R Kawase, T Yamashita, M Yuasa-Kawase, K Nakatani, D Masuda, T Ohama, T Sonobe, M Shirai, I Komuro, S Yamashita |
PloS one | 2013 |
|
Reduced paraoxonase 1 activity as a marker for severe coronary artery disease
C Zhou, J Cao, L Shang, C Tong, H Hu, H Wang, D Fan, H Yu |
Disease Markers | 2013 |
|
Visfatin induces cholesterol accumulation in macrophages through up-regulation of scavenger receptor-A and CD36
F Zhou, Y Pan, Z Huang, Y Jia, X Zhao, Y Chen, J Diao, Q Wan, X Cui |
Cell Stress and Chaperones | 2013 |
|
The Complex Fate in Plasma of Gadolinium Incorporated into High-Density Lipoproteins Used for Magnetic Imaging of Atherosclerotic Plaques
A Barazza, C Blachford, O Even-Or, VA Joaquin, K Briley-Saebo, W Chen, XC Jiang, WJ Mulder, DP Cormode, ZA Fayad, EA Fisher |
Bioconjugate Chemistry | 2013 |
|
Xanthohumol ameliorates atherosclerotic plaque formation, hypercholesterolemia, and hepatic steatosis in ApoE -deficient mice
P Doddapattar, B Radović, JV Patankar, S Obrowsky, K Jandl, C Nusshold, D Kolb, N Vujić, L Doshi, PG Chandak, M Goeritzer, H Ahammer, G Hoefler, W Sattler, D Kratky |
Molecular Nutrition & Food Research | 2013 |
|
Chewing the fat: Genetic approaches to model dyslipidemia-induced diabetic neuropathy in mice
BL Guilford, DE Wright |
Experimental Neurology | 2013 |
|
Effects of lifestyle modifications on cognitive impairments in a mouse model of hypercholesterolemia
EL Moreira, AS Aguiar, CR de Carvalho, DB Santos, J Oliveira, AF de Bem, JC Xikota, R Walz, M Farina, RD Prediger |
Neuroscience Letters | 2013 |
|
eLS
YC Chang, YH Yu, LM Chuang |
Encyclopedia of Life Sciences | 2013 |
|
Connexin Cell Communication Channels: Roles in the Immune System and Immunopathology
M Chanson, M Koval |
Connexin Cell Communication Channels: Roles in the Immune System and Immunopathology | 2013 |
|
Association mapping of quantitative trait loci for carcass and meat quality traits at the central part of chromosome 2 in Italian Large White pigs
S Čepica, P Zambonelli, F Weisz, M Bigi, A Knoll, Z Vykoukalová, M Masopust, M Gallo, L Buttazzoni, R Davoli |
Meat Science | 2013 |
|
Animal Models for the Study of Human Disease
HA Lawson |
Animal Models for the Study of Human Disease | 2013 |
|
Function of seipin: New insights from Bscl2/seipin knockout mouse models
L Dollet, J Magré, B Cariou, X Prieur |
Biochimie | 2013 |
|
Diphenyl Diselenide Prevents Cortico-cerebral Mitochondrial Dysfunction and Oxidative Stress Induced by Hypercholesterolemia in LDL Receptor Knockout Mice
J Oliveira, EL Moreira, G Mancini, MA Hort, A Latini, RM Ribeiro-do-Valle, M Farina, JB da Rocha, AF Bem |
Neurochemical Research | 2013 |
|
PEGylated helper-dependent adenoviral vector expressing human Apo A-I for gene therapy in LDLR-deficient mice
E Leggiero, D Astone, V Cerullo, B Lombardo, C Mazzaccara, G Labruna, L Sacchetti, F Salvatore, M Croyle, L Pastore |
Gene Therapy | 2013 |
|
Cholesterol accumulation caused by low density lipoprotein receptor deficiency or a cholesterol-rich diet results in ectopic bone formation during experimental osteoarthritis
W Munter, AB Blom, MM Helsen, B Walgreen, PM van der Kraan, LA Joosten, WB van Berg, PL van Lent |
Arthritis Research & Therapy | 2013 |
|
Gold Nanocrystal Labeling Allows Low-Density Lipoprotein Imaging from the Subcellular to Macroscopic Level
IE Allijn, W Leong, J Tang, A Gianella, AJ Mieszawska, F Fay, G Ma, S Russell, CB Callo, RE Gordon, E Korkmaz, JA Post, Y Zhao, HC Gerritsen, A Thran, R Proksa, H Daerr, G Storm, V Fuster, EA Fisher, ZA Fayad, WJ Mulder, DP Cormode |
ACS Nano | 2013 |
|
Reciprocal interference of experimental dyslipidemia and food allergy in the evolution of both diseases
AC Gomes-Santos, JL Gonçalves, TR Fonseca, AR Marques, LP Dourado, DC Cara, JI Alvarez-Leite |
ISRN Allergy | 2013 |
|
SEC24A deficiency lowers plasma cholesterol through reduced PCSK9 secretion
XW Chen, H Wang, K Bajaj, P Zhang, ZX Meng, D Ma, Y Bai, HH Liu, E Adams, A Baines, G Yu, MA Sartor, B Zhang, Z Yi, J Lin, SG Young, R Schekman, D Ginsburg |
eLife | 2013 |
|
Quercetin prevents left ventricular hypertrophy in the Apo E knockout mouse
E Ulasova, J Perez, BG Hill, WE Bradley, DW Garber, A Landar, S Barnes, J Prasain, DA Parks, LJ Dell'italia, VM Darley-Usmar |
Redox Biology | 2013 |
|
Developmental exposure to second-hand smoke increases adult atherogenesis and alters mitochondrial DNA copy number and deletions in apoE(-/-) mice
JL Fetterman, M Pompilius, DG Westbrook, D Uyeminami, J Brown, KE Pinkerton, SW Ballinger |
PloS one | 2013 |
|
Microarray gene expression profiling reveals antioxidant-like effects of angiotensin II inhibition in atherosclerosis
JA Alla, YE Faramawy, U Quitterer |
Frontiers in physiology | 2013 |
|
Secretion and signaling activities of lipoprotein-associated hedgehog and non-sterol-modified hedgehog in flies and mammals
W Palm, MM Swierczynska, V Kumari, M Ehrhart-Bornstein, SR Bornstein, S Eaton |
PLoS Biology | 2013 |
|
Sildenafil restores endothelial function in the apolipoprotein E knockout mouse
CM Balarini, MA Leal, IB Gomes, TM Pereira, AL Gava, SS Meyrelles, EC Vasquez |
Journal of Translational Medicine | 2013 |
|
Modelos experimentales de aterosclerosis
CG Santos-Gallego, JJ Badimon, B Ibáñez |
Revista Española de Cardiología Suplementos | 2013 |
|
VPO1 Mediates ApoE Oxidation and Impairs the Clearance of Plasma Lipids
Y Yang, Z Cao, L Tian, WT Garvey, G Cheng, M Makishima |
PloS one | 2013 |
|
Cloning and expression of an anti-LDL(-) single-chain variable fragment, and its inhibitory effect on experimental atherosclerosis
SM Kazuma, MF Cavalcante, AE Telles, AQ Maranhão, DS Abdalla |
mAbs | 2013 |
|
Contribution of the WHHL rabbit, an animal model of familial hypercholesterolemia, to elucidation of the anti-atherosclerotic effects of statins
M Shiomi, T Koike, T Ito |
Atherosclerosis | 2013 |
|
Mouse models of plaque rupture:
T Matoba, K Sato, K Egashira |
Current Opinion in Lipidology | 2013 |
|
The Genetic and Metabolic Determinants of Cardiovascular Complications in Type 2 Diabetes: Recent Insights from Animal Models and Clinical Investigations
RK Avramoglu, MA Laplante, KL Quang, Y Deshaies, JP Després, E Larose, P Mathieu, P Poirier, L Pérusse, MC Vohl, G Sweeney, S Ylä-Herttuala, M Laakso, M Uusitupa, A Marette |
Canadian Journal of Diabetes | 2013 |
|
Diphenyl diselenide differently modulates cardiovascular redox responses in young adult and middle-aged low-density lipoprotein receptor knockout hypercholesterolemic mice: Diphenyl diselenide, LDLr −/− and age
G Mancini, J Oliveira, MA Hort, EL Moreira, RM Ribeiro-do-Valle, JB Rocha, AF de Bem |
Journal of Pharmacy and Pharmacology | 2013 |
|
Atherosclerosis: Comparative Pathogenesis, Lipoprotein Metabolism, and Avian and Exotic Companion Mammal Models
H Beaufrère |
Journal of Exotic Pet Medicine | 2013 |
|
Gene Therapy
S Nimesh |
Gene Therapy | 2013 |
|
Microscope-based near-infrared stereo-imaging system for quantifying the motion of the murine epicardial coronary arteries in vivo
DS Long, H Zhu, MH Friedman |
Journal of Biomedical Optics | 2013 |
|
Distilling Pathophysiology from Complex Disease Genetics
A Chakravarti, AG Clark, VK Mootha |
Cell | 2013 |
|
S-nitrosylation of ARH is required for LDL uptake by the LDL receptor[S]
Z Zhao, S Pompey, H Dong, J Weng, R Garuti, P Michaely |
Journal of lipid research | 2013 |
|
Granzyme B degrades extracellular matrix and contributes to delayed wound closure in apolipoprotein E knockout mice
PR Hiebert, D Wu, DJ Granville |
Cell Death and Differentiation | 2013 |
|
The Role of Maternal-Fetal Cholesterol Transport in Early Fetal Life: Current Insights1
ME Baardman, WS Kerstjens-Frederikse, RM Berger, MK Bakker, RM Hofstra, T Plösch |
Biology of reproduction | 2013 |
|
ILDR2: An Endoplasmic Reticulum Resident Molecule Mediating Hepatic Lipid Homeostasis
K Watanabe, E Watson, ML Cremona, EJ Millings, JH Lefkowitch, SG Fischer, CA LeDuc, RL Leibel, GV Gnoni |
PloS one | 2013 |
|
Distinct metabolic and vascular effects of dietary triglycerides and cholesterol in atherosclerotic and diabetic mouse models
MA Laplante, A Charbonneau, RK Avramoglu, P Pelletier, X Fang, H Bachelard, S Ylä-Herttuala, M Laakso, JP Després, Y Deshaies, G Sweeney, P Mathieu, A Marette |
American journal of physiology. Endocrinology and metabolism | 2013 |
|
PI3K p110γ Deletion Attenuates Murine Atherosclerosis by Reducing Macrophage Proliferation but Not Polarization or Apoptosis in Lesions
TM Zotes, CF Arias, JJ Fuster, R Spada, S Pérez-Yagüe, E Hirsch, M Wymann, AC Carrera, V Andrés, DF Barber, E Lutgens |
PloS one | 2013 |
|
Protective role of L -carnitine and vitamin E on the testis of atherosclerotic rats
AF Salama, SM Kasem, E Tousson, MK Elsisy |
Toxicology and industrial health | 2013 |
|
Generation of porcine fibroblasts overexpressing 11β-HSD1 with adipose tissue-specific aP2 promoter as a porcine model of metabolic syndrome
EM Jung, BS An, YK Kim, YH Jeong, WS Hwang, EB Jeung |
Molecular medicine reports | 2013 |
|
Role of Proteases in Cellular Dysfunction
NS Dhalla, S Chakraborti |
2013 | |
|
Nutrition and Diet in Menopause
CJ Martin, RR Watson, VR Preedy |
2013 | |
|
Diphenyl diselenide prevents cortico-cerebral mitochondrial dysfunction and oxidative stress induced by hypercholesterolemia in LDL receptor knockout mice.
de Oliveira J, Moreira EL, Mancini G, Hort MA, Latini A, Ribeiro-do-Valle RM, Farina M, da Rocha JB, de Bem AF |
Neurochemical Research | 2013 |
|
Scavenger receptor-mediated uptake controls the bioactivity of the prototypic NKT cell agonist α-galactosylceramide in vivo
Stefan Freigang, Elise Landais, Victoria Zadorozhny, Lisa Kain, Kenji Yoshida, Yang Liu, Shenglou Deng, Wulf Palinski, Paul Savage, Albert S. Bendelac, Luc Teyton |
Journal of Clinical Investigation | 2012 |
|
Apolipoprotein B100 is a suppressor of Staphylococcus aureus-induced innate immune responses in humans and mice: Innate immunity
S Sigel, S Bunk, T Meergans, B Doninger, K Stich, T Stulnig, K Derfler, J Hoffmann, S Deininger, S Aulock, S Knapp |
European Journal of Immunology | 2012 |
|
Low-density lipoprotein receptor deficiency causes impaired osteoclastogenesis and increased bone mass in mice because of defect in osteoclastic cell-cell fusion
M Okayasu, M Nakayachi, C Hayashida, J Ito, T Kaneda, M Masuhara, N Suda, T Sato, Y Hakeda |
The Journal of biological chemistry | 2012 |
|
The Role of Complement in the Development and Manifestation of Murine Atherogenic Inflammation: Novel Avenues
L Francescut, T Steiner, S Byrne, K Cianflone, S Francis, C Stover |
Journal of Innate Immunity | 2012 |
|
Genetic Basis of Atherosclerosis: Insights From Mice and Humans
IM Stylianou, RC Bauer, MP Reilly, DJ Rader, AJ Marian, H Watkins, C Seidman |
Circulation research | 2012 |
|
Macrophages, dendritic cells, and regression of atherosclerosis
JE Feig, JL Feig |
Frontiers in physiology | 2012 |
|
Phosphoinositides I: Enzymes of Synthesis and Degradation
T Balla, M Wymann, JD York |
2012 | |
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Phosphoinositides I: Enzymes of Synthesis and Degradation
T Balla, M Wymann, JD York |
2012 | |
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Phosphoinositides I: Enzymes of Synthesis and Degradation
T Balla, M Wymann, JD York |
2012 | |
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Cardiovascular Protection by ApoE and ApoE-HDL Linked to Suppression of ECM Gene Expression and Arterial Stiffening
D Kothapalli, SL Liu, YH Bae, J Monslow, T Xu, EA Hawthorne, FJ Byfield, P Castagnino, S Rao, DJ Rader, E Puré, MC Phillips, S Lund-Katz, PA Janmey, RK Assoian |
Cell Reports | 2012 |
|
Inflammation and diabetes-accelerated atherosclerosis: myeloid cell mediators
JE Kanter, KE Bornfeldt |
Trends in Endocrinology & Metabolism | 2012 |
|
Cardiac and vascular phenotypes in the apolipoprotein E-deficient mouse
EC Vasquez, VA Peotta, AL Gava, TM Pereira, SS Meyrelles |
Journal of Biomedical Science | 2012 |
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LDL Receptor Knock-Out Mice Are a Physiological Model Particularly Vulnerable to Study the Onset of Inflammation in Non-Alcoholic Fatty Liver Disease
V Bieghs, PJ van Gorp, K Wouters, T Hendrikx, MJ Gijbels, M Bilsen, J Bakker, CJ Binder, D Lütjohann, B Staels, MH Hofker, R Shiri-Sverdlov, WK Syn |
PloS one | 2012 |
|
PPARγ COUNTERACTS LRP1-INDUCED VASCULAR CALCIFICATION BY INHIBITING A WNT5A SIGNALING PATHWAY
E Woldt, J Terrand, M Mlih, RL Matz, V Bruban, F Coudane, S Foppolo, ZE Asmar, ME Chollet, E Ninio, A Bednarczyk, D Thiersé, C Schaeffer, AV Dorsselaer, C Boudier, W Wahli, P Chambon, D Metzger, J Herz, P Boucher |
Nature Communications | 2012 |
|
Transcriptional integration of metabolism by the nuclear sterol-activated receptors LXR and FXR
AC Calkin, P Tontonoz |
Nature Reviews Molecular Cell Biology | 2012 |
|
Apolipoprotein E gene polymorphism: effects on plasma lipids and risk of type 2 diabetes and coronary artery disease
R Chaudhary, A Likidlilid, T Peerapatdit, D Tresukosol, S Srisuma, S Ratanamaneechat, C Sriratanasathavorn |
Cardiovascular Diabetology | 2012 |
|
Regulation of Atherosclerosis and Associated Risk Factors by Adenosine and Adenosine Receptors
M Koupenova, H Johnston-Cox, K Ravid |
Current Atherosclerosis Reports | 2012 |
|
Impaired LDL Receptor-Related Protein 1 Translocation Correlates with Improved Dyslipidemia and Atherosclerosis in apoE-Deficient Mice
PL Gordts, A Bartelt, SK Nilsson, W Annaert, C Christoffersen, LB Nielsen, J Heeren, AJ Roebroek |
PloS one | 2012 |
|
Feedback Regulation of Cholesterol Uptake by the LXR-IDOL-LDLR Axis
L Zhang, K Reue, LG Fong, SG Young, P Tontonoz |
Arteriosclerosis, thrombosis, and vascular biology | 2012 |
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Targeted In Situ Gene Correction of Dysfunctional APOE Alleles to Produce Atheroprotective Plasma ApoE3 Protein
I Papaioannou, JP Simons, JS Owen |
Cardiology Research and Practice | 2012 |
|
Current Protocols in Immunology
E Maganto-Garcia, M Tarrio, AH Lichtman |
Current Protocols in Immunology | 2012 |
|
Animal models of age related macular degeneration
ME Pennesi, M Neuringer, RJ Courtney |
Molecular Aspects of Medicine | 2012 |
|
Inhibition of hypothalamic inflammation reverses diet-induced insulin resistance in the liver
M Milanski, AP Arruda, A Coope, LM Ignacio-Souza, CE Nunez, EA Roman, T Romanatto, LB Pascoal, AM Caricilli, MA Torsoni, PO Prada, MJ Saad, LA Velloso |
Diabetes | 2012 |
|
Beyond genome-wide association studies: the usefulness of mouse genetics in understanding the complex etiology of atherosclerosis
CL Welch |
Arteriosclerosis, thrombosis, and vascular biology | 2012 |
|
From Omics to Drug Metabolism and High Content Screen of Natural Product in Zebrafish: A New Model for Discovery of Neuroactive Compound
MW Hung, ZJ Zhang, S Li, B Lei, S Yuan, GZ Cui, PM Hoi, K Chan, SM Lee |
Evidence-based complementary and alternative medicine : eCAM | 2012 |
|
Natural killer T cells are required for lipopolysaccharide-mediated enhancement of atherosclerosis in apolipoprotein E-deficient mice
Y Andoh, H Ogura, M Satoh, K Shimano, H Okuno, S Fujii, N Ishimori, K Eshima, H Tamauchi, T Otani, Y Nakai, LV Kaer, H Tsutsui, K Onoé, K Iwabuchi |
Immunobiology | 2012 |
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PAI-1, progress in understanding the clinical problem and its aetiology
T Iwaki, T Urano, K Umemura |
British Journal of Haematology | 2012 |
|
New drug discovery strategies for rheumatoid arthritis: a niche for nonhuman primate models to address systemic complications in inflammatory arthritis
M Vierboom, E Breedveld, BA Hart |
Expert Opinion on Drug Discovery | 2012 |
|
Nuclear receptor mediated mechanisms of macrophage cholesterol metabolism
ZS Nagy, Z Czimmerer, L Nagy |
Molecular and Cellular Endocrinology | 2012 |
|
Regulation of cholesterol homeostasis
MY van der Wulp, HJ Verkade, AK Groen |
Molecular and Cellular Endocrinology | 2012 |
|
Low-Density Lipoprotein Receptor (LDLR) Family Orchestrates Cholesterol Homeostasis
GW Go, A Mani |
The Yale journal of biology and medicine | 2012 |
|
Cardioprotective effects of a proanthocyanidin-rich fraction from Croton celtidifolius Baill: Focus on atherosclerosis
MA Hort, MR Straliotto, MS Duz, PM Netto, CB Souza, T Schulz, H Horst, MG Pizzolatti, AF de Bem, RM Ribeiro-do-Valle |
Food and Chemical Toxicology | 2012 |
|
Green tea extract reverses endothelial dysfunction and reduces atherosclerosis progression in homozygous knockout low-density lipoprotein receptor mice
J Minatti, E Wazlawik, MA Hort, FL Zaleski, RM Ribeiro-do-Valle, M Maraschin, EL da Silva |
Nutrition Research | 2012 |
|
Onion peel extract increases hepatic low-density lipoprotein receptor and ATP-binding cassette transporter A1 messenger RNA expressions in Sprague-Dawley rats fed a high-fat diet
SM Lee, J Moon, HJ Do, JH Chung, KH Lee, YJ Cha, MJ Shin |
Nutrition Research | 2012 |
|
Pharmacodynamic and pharmacokinetic analysis of apoE4 [L261A, W264A, F265A, L268A, V269A], a recombinant apolipoprotein E variant with improved biological properties
A Lampropoulou, VI Zannis, KE Kypreos |
Biochemical Pharmacology | 2012 |
|
MicroRNAs in atherosclerosis
KC Chen, SH Juo |
The Kaohsiung Journal of Medical Sciences | 2012 |
|
Anti-Atherogenic Effects of a Phenol-Rich Fraction from Brazilian Red Wine ( Vitis labrusca L.) in Hypercholesterolemic Low-Density Lipoprotein Receptor Knockout Mice
MA Hort, EZ Schuldt, ÂC Bet, S DalBó, JM Siqueira, C Ianssen, F Abatepaulo, HP de Souza, B Veleirinho, M Maraschin, RM Ribeiro-do-Valle |
Journal of Medicinal Food | 2012 |
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The Role of Dyslipidemia on Ocular Surface, Lacrimal and Meibomian Gland Structure and Function
CM Módulo, EB Filho, LT Malki, AC Dias, JC de Souza, HC Oliveira, ÍC Jorge, IB Gomes, SS Meyrelles, EM Rocha |
Current Eye Research | 2012 |
|
Protective role of L-carnitine and vitamin E on the kidney of atherosclerotic rats
AF Salama, SM Kasem, E Tousson, MK Elsisy |
Biomedicine & Aging Pathology | 2012 |
|
Small animal positron emission tomography imaging and in vivo studies of atherosclerosis
AM Hag, RS Ripa, SF Pedersen, RP Bodholdt, A Kjaer |
Clinical Physiology and Functional Imaging | 2012 |
|
Improvements of Atherosclerosis and Hepatic Oxidative Stress are Independent of Exercise Intensity in LDLr-/- Mice
BG Teodoro, AJ Natali, SA Fernandes, LA da Silva, RA de Pinho, SL da Matta, MC Peluzio |
Journal of Atherosclerosis and Thrombosis | 2012 |
|
The plasma concentration of HDL-associated apoM is influenced by LDL receptor-mediated clearance of apoB-containing particles
C Christoffersen, M Benn, PM Christensen, PL Gordts, AJ Roebroek, R Frikke-Schmidt, A Tybjaerg-Hansen, B Dahlbäck, LB Nielsen |
Journal of lipid research | 2012 |
|
Modified methylenedioxyphenol analogs lower LDL cholesterol through induction of LDL receptor expression
Z Ying, R Desikan, X Xu, A Maiseyeu, C Liu, Q Sun, O Ziouzenkova, S Parthasarathy, S Rajagopalan |
Journal of lipid research | 2012 |
|
Humanin prevents intra-renal microvascular remodeling and inflammation in hypercholesterolemic ApoE deficient mice
X Zhang, VH Urbieta-Caceres, A Eirin, CC Bell, JA Crane, H Tang, KL Jordan, YK Oh, XY Zhu, MJ Korsmo, AR Bachar, P Cohen, A Lerman, LO Lerman |
Life Sciences | 2012 |
|
Coronary artery wall imaging in mice using osmium tetroxide and micro-computed tomography (micro-CT)
VM Pai, M Kozlowski, D Donahue, E Miller, X Xiao, MY Chen, ZX Yu, P Connelly, K Jeffries, H Wen |
Journal of Anatomy | 2012 |
|
D-Carnosine octylester attenuates atherosclerosis and renal disease in ApoE null mice fed a Western diet through reduction of carbonyl stress and inflammation
S Menini, C Iacobini, C Ricci, A Scipioni, CB Fantauzzi, A Giaccari, E Salomone, R Canevotti, A Lapolla, M Orioli, G Aldini, G Pugliese |
British Journal of Pharmacology | 2012 |
|
GPIHBP1 and the intravascular processing of triglyceride-rich lipoproteins
O Adeyo, CN Goulbourne, A Bensadoun, AP Beigneux, LG Fong, SG Young |
Journal of Internal Medicine | 2012 |
|
Hypercholesterolemic LDL receptor-deficient mice mount a neutrophilic response to tuberculosis despite the timely expression of protective immunity
GW Martens, T Vallerskog, H Kornfeld |
Journal of leukocyte biology | 2012 |
|
Oxysterol Sulfation by SULT2B1b Suppresses LXR/SREBP-1c Signaling Pathway and Reduces Serum and Hepatic Lipids in Mouse Models of NAFLD
Q Bai, X Zhang, L Xu, G Kakiyama, D Heuman, A Sanyal, WM Pandak, L Yin, W Xie, S Ren |
Metabolism | 2012 |
|
Proprotein convertase subtilisin/kexin type 9 deficiency reduces melanoma metastasis in liver
X Sun, R Essalmani, R Day, AM Khatib, NG Seidah, A Prat |
Neoplasia (New York, N.Y.) | 2012 |
|
The effect of AVE 0991, nebivolol and doxycycline on inflammatory mediators in an apoE-knockout mouse model of atherosclerosis
J Jawien, J Toton-Zuranska, K Kus, M Pawlowska, R Olszanecki, R Korbut |
Medical science monitor : international medical journal of experimental and clinical research | 2012 |
|
Proprotein Convertase Subtilisin/Kexin Type 9 Deficiency Reduces Melanoma Metastasis in Liver12
X Sun, R Essalmani, R Day, AM Khatib, NG Seidah, A Prat |
Neoplasia (New York, N.Y.) | 2012 |
|
Modified methylenedioxyphenol analogs lower LDL cholesterol through induction of LDL receptor expression[S]
Z Ying, R Desikan, X Xu, A Maiseyeu, C Liu, Q Sun, O Ziouzenkova, S Parthasarathy, S Rajagopalan |
Journal of lipid research | 2012 |
|
Impact of high-fat diet on antioxidant status, vascular wall thickening and cardiac function in adult female LDLR<sup>–/–</sup> mice
S Delemasure, C Richard, S Gambert, JC Guilland, C Vergely, P Dutartre, L Rochette, JL Connat |
World Journal of Cardiovascular Diseases | 2012 |
|
Genetic Susceptibility to Atherosclerosis
S Kovacic, M Bakran |
Stroke Research and Treatment | 2012 |
|
Macrophage-Specific ApoE Gene Repair Reduces Diet-Induced Hyperlipidemia and Atherosclerosis in Hypomorphic Apoe Mice
N Gaudreault, N Kumar, VR Olivas, D Eberlé, JH Rapp, RL Raffai, M Lisanti |
PloS one | 2012 |
|
Apolipoprotein E does not cross the blood-cerebrospinal fluid barrier, as revealed by an improved technique for sampling CSF from mice
M Liu, DG Kuhel, L Shen, DY Hui, SC Woods |
American Journal of Physiology - Regulatory, Integrative and Comparative Physiology | 2012 |
|
Proteomic Analysis of Aortae from Human Lipoprotein(a) Transgenic Mice Shows an Early Metabolic Response Independent of Atherosclerosis
EJ Rodger, RJ Suetani, GT Jones, T Kleffmann, A Carne, M Legge, SP McCormick, A Zernecke |
PloS one | 2012 |
|
Transcriptional Activation of Low-Density Lipoprotein Receptor Gene by DJ-1 and Effect of DJ-1 on Cholesterol Homeostasis
S Yamaguchi, T Yamane, K Takahashi-Niki, I Kato, T Niki, MS Goldberg, J Shen, K Ishimoto, T Doi, SM Iguchi-Ariga, H Ariga, DY Jin |
PloS one | 2012 |
|
Regression of Atherosclerosis Is Characterized by Broad Changes in the Plaque Macrophage Transcriptome
JE Feig, Y Vengrenyuk, V Reiser, C Wu, A Statnikov, CF Aliferis, MJ Garabedian, EA Fisher, O Puig, G Colombo |
PloS one | 2012 |
|
Hyperlipidemia and Atherosclerotic Lesion Development in Ldlr-Deficient Mice on a Long-Term High-Fat Diet
Y Ma, W Wang, J Zhang, Y Lu, W Wu, H Yan, Y Wang, M Federici |
PloS one | 2012 |
|
High-Resolution Association Mapping of Atherosclerosis Loci in Mice
BJ Bennett, L Orozco, E Kostem, A Erbilgin, M Dallinga, I Neuhaus, B Guan, X Wang, E Eskin, AJ Lusis |
Arteriosclerosis, thrombosis, and vascular biology | 2012 |
|
Endocytic receptor-mediated control of morphogen signaling
TE Willnow, A Christ, A Hammes |
Development (Cambridge, England) | 2012 |
|
Animal Models of Cardiovascular Diseases
C Zaragoza, C Gomez-Guerrero, JL Martin-Ventura, L Blanco-Colio, B Lavin, B Mallavia, C Tarin, S Mas, A Ortiz, J Egido |
Journal of Biomedicine and Biotechnology | 2011 |
|
Lack of LDL Receptor Enhances Amyloid Deposition and Decreases Glial Response in an Alzheimer's Disease Mouse Model
L Katsouri, S Georgopoulos |
PloS one | 2011 |
|
Adipocyte Enhancer-Binding Protein 1 (AEBP1) (a Novel Macrophage Proinflammatory Mediator) Overexpression Promotes and Ablation Attenuates Atherosclerosis in ApoE−/− and LDLR−/− Mice
O Bogachev, A Majdalawieh, X Pan, L Zhang, HS Ro |
Molecular Medicine | 2011 |
|
NF-κB, inflammation and metabolic disease
RG Baker, MS Hayden, S Ghosh |
Cell Metabolism | 2011 |
|
Animal, In Vitro, and Ex Vivo Models of Flow-Dependent Atherosclerosis: Role of Oxidative Stress
A Rezvan, CW Ni, N Alberts-Grill, H Jo |
Antioxidants & Redox Signaling | 2011 |
|
Dietary fat impacts fetal growth and metabolism: uptake of chylomicron remnant core lipids by the placenta
SL Rebholz, KT Burke, Q Yang, P Tso, LA Woollett |
American journal of physiology. Endocrinology and metabolism | 2011 |
|
Pathway-Wide Association Study Implicates Multiple Sterol Transport and Metabolism Genes in HDL Cholesterol Regulation
K Wang, AC Edmondson, M Li, F Gao, AN Qasim, JM Devaney, MS Burnett, DM Waterworth, V Mooser, SF Grant, SE Epstein, MP Reilly, H Hakonarson, DJ Rader |
Frontiers in Genetics | 2011 |
|
Dietary Cholesterol Reduces Plasma Triacylglycerol in Apolipoprotein E-Null Mice: Suppression of Lipin-1 and -2 in the Glycerol-3-Phosphate Pathway
T Obama, S Nagaoka, K Akagi, R Kato, N Horiuchi, Y Horai, T Aiuchi, S Arata, T Yamaguchi, M Watanabe, H Itabe, JM Lobaccaro |
PloS one | 2011 |
|
Comparative Endocrinology of Aging and Longevity Regulation
JB Allard, C Duan |
Frontiers in Endocrinology | 2011 |
|
Sexual dimorphism in ischemic stroke: lessons from the laboratory
B Manwani, LD McCullough |
Women's health (London, England) | 2011 |
|
Effects of macrophage-specific adiponectin expression on lipid metabolism in vivo
N Luo, X Wang, BH Chung, MH Lee, RL Klein, WT Garvey, Y Fu |
American journal of physiology. Endocrinology and metabolism | 2011 |
|
Atomic Force Microscopy in Biomedical Research
PC Braga, D Ricci |
2011 | |
|
Atomic Force Microscopy in Biomedical Research
PC Braga, D Ricci |
2011 | |
|
Atomic Force Microscopy in Biomedical Research
PC Braga, D Ricci |
2011 | |
|
Atomic Force Microscopy in Biomedical Research
PC Braga, D Ricci |
2011 | |
|
Atomic Force Microscopy in Biomedical Research
PC Braga, D Ricci |
2011 | |
|
Atomic Force Microscopy in Biomedical Research
PC Braga, D Ricci |
2011 | |
|
Spontaneously diabetic Ins2+/Akita:apoE-deficient mice exhibit exaggerated hypercholesterolemia and atherosclerosis
JY Jun, Z Ma, L Segar |
American journal of physiology. Endocrinology and metabolism | 2011 |
|
Impairment of Nitrergic System and Delayed Gastric Emptying in Low Density Lipoprotein Receptor (LDLR) Deficient Female Mice
PR Gangula, V Chinnathambi, AB Hale, S Mukhopadhyay, KM Channon, K Ravella |
Neurogastroenterology and Motility | 2011 |
|
Lack of acyl-CoA:diacylglycerol acyltransferase 1 reduces intestinal cholesterol absorption and attenuates atherosclerosis in apolipoprotein E knockout mice
PG Chandak, S Obrowsky, B Radovic, P Doddapattar, E Aflaki, A Kratzer, LS Doshi, S Povoden, H Ahammer, G Hoefler, S Levak-Frank, D Kratky |
Biochimica et Biophysica Acta | 2011 |
|
Intermittent hypoxia inhibits clearance of triglyceride-rich lipoproteins and inactivates adipose lipoprotein lipase in a mouse model of sleep apnoea
LF Drager, J Li, MK Shin, C Reinke, NR Aggarwal, JC Jun, S Bevans-Fonti, C Sztalryd, SM O'Byrne, O Kroupa, G Olivecrona, WS Blaner, VY Polotsky |
European Heart Journal | 2011 |
|
Human apolipoprotein E genotypes differentially modify house dust mite-induced airway disease in mice
X Yao, C Dai, K Fredriksson, J Lam, M Gao, KJ Keeran, GZ Nugent, X Qu, ZX Yu, N Jeffries, JP Lin, M Kaler, R Shamburek, R Costello, G Csako, M Dahl, BG Nordestgaard, AT Remaley, SJ Levine |
American journal of physiology. Lung cellular and molecular physiology | 2011 |
|
Deficiency in apolipoprotein E has a protective effect on diet-induced nonalcoholic fatty liver disease in mice
EA Karavia, DJ Papachristou, I Kotsikogianni, I Giopanou, KE Kypreos |
The FEBS journal | 2011 |
|
Domains of apoE4 required for the biogenesis of apoE-containing HDL
AM Vezeridis, A Chroni, VI Zannis |
Annals of Medicine | 2011 |
|
Apolipoprotein E: from lipid transport to neurobiology
PS Hauser, V Narayanaswami, RO Ryan |
Progress in Lipid Research | 2011 |
|
Animal models of calcific aortic valve disease
KL Sider, MC Blaser, CA Simmons |
International Journal of Inflammation | 2011 |
|
Encyclopedia of Life Sciences
B Dahlbäck |
Encyclopedia of Life Sciences | 2011 |
|
Oxidative Stress and Disease
I Paur, M Carlsen, B Halvorsen, R Blomhoff |
Herbal Medicine | 2011 |
|
Progress in Molecular Biology and Translational Science
JF Wilkins, F Úbeda |
Modifications of Nuclear DNA and its Regulatory Proteins | 2011 |
|
Advances in Clinical Chemistry
M Mahler |
Advances in Clinical Chemistry Volume 54 | 2011 |
|
Angptl4 deficiency decreases serum triglyceride levels in low-density lipoprotein receptor knockout mice and streptozotocin-induced diabetic mice
H Adachi, T Kondo, GY Koh, A Nagy, Y Oike, E Araki |
Biochemical and Biophysical Research Communications | 2011 |
|
Transplantation of Human Adipose Tissue-Derived Multilineage Progenitor Cells Reduces Serum Cholesterol in Hyperlipidemic Watanabe Rabbits
H Okura, A Saga, Y Fumimoto, M Soeda, M Moriyama, H Moriyama, K Nagai, CM Lee, S Yamashita, A Ichinose, T Hayakawa, A Matsuyama |
Tissue Engineering Part C: Methods | 2011 |
|
Discovery of biomarker candidates for coronary artery disease from an APOE-knock out mouse model using iTRAQ-based multiplex quantitative proteomics
L Jing, CE Parker, D Seo, MW Hines, N Dicheva, Y Yu, D Schwinn, GS Ginsburg, X Chen |
PROTEOMICS | 2011 |
|
Animal models for the atherosclerosis research: a review
L Xiangdong, L Yuanwu, Z Hua, R Liming, L Qiuyan, L Ning |
Protein & Cell | 2011 |
|
Lower expression of PKAα impairs insulin secretion in islets isolated from low-density lipoprotein receptor (LDLR−/−) knockout mice
ML Bonfleur, RA Ribeiro, SL Balbo, EC Vanzela, EM Carneiro, HC de Oliveira, AC Boschero |
Metabolism | 2011 |
|
Correlation Between Local Hemodynamics and Lesion Distribution in a Novel Aortic Regurgitation Murine Model of Atherosclerosis
Y Hoi, YQ Zhou, X Zhang, RM Henkelman, DA Steinman |
Annals of Biomedical Engineering | 2011 |
|
Diphenyl Diselenide Effectively Reduces Atherosclerotic Lesions in LDLr −/− Mice by Attenuation of Oxidative Stress and Inflammation
MA Hort, MR Straliotto, PM Netto, JB da Rocha, AF de Bem, RM Ribeiro-do-Valle |
Journal of Cardiovascular Pharmacology | 2011 |
|
Inhibition of SREBP by a Small Molecule, Betulin, Improves Hyperlipidemia and Insulin Resistance and Reduces Atherosclerotic Plaques
JJ Tang, JG Li, W Qi, WW Qiu, PS Li, BL Li, BL Song |
Cell Metabolism | 2011 |
|
Aortic valve disease and treatment: The need for naturally engineered solutions
JT Butcher, GJ Mahler, LA Hockaday |
Advanced Drug Delivery Reviews | 2011 |
|
HMG-CoA reductase inhibitor augments the serum total cholesterol-lowering effect of human adipose tissue-derived multilineage progenitor cells in hyperlipidemic homozygous Watanabe rabbits
A Saga, H Okura, M Soeda, J Tani, Y Fumimoto, H Komoda, M Moriyama, H Moriyama, S Yamashita, A Ichinose, T Daimon, T Hayakawa, A Matsuyama |
Biochemical and Biophysical Research Communications | 2011 |
|
RNAi-mediated knockdown of HMG CoA reductase enhances gene expression from physiologically regulated low-density lipoprotein receptor therapeutic vectors in vivo
O Hibbitt, S Agkatsev, C Owen, M Cioroch, L Seymour, K Channon, R Wade-Martins |
Gene Therapy | 2011 |
|
Impact of sphingomyelin levels on coronary heart disease and left ventricular systolic function in humans
X Chen, A Sun, Y Zou, J Ge, JM Lazar, XC Jiang |
Nutrition & Metabolism | 2011 |
|
Efficient In Vivo Delivery of siRNA Into Brain Capillary Endothelial Cells Along With Endogenous Lipoprotein
H Kuwahara, K Nishina, K Yoshida, T Nishina, M Yamamoto, Y Saito, W Piao, M Yoshida, H Mizusawa, T Yokota |
Molecular Therapy | 2011 |
|
The inhibition of lipoprotein-associated phospholipase A2 exerts beneficial effects against atherosclerosis in LDLR-deficient mice
M Hu, J Zhang, W Wang, W Wu, Y Ma, W Chen, Y Wang |
Acta Pharmacologica Sinica | 2011 |
|
Positive correlation between elevated plasma cholesterol levels and cognitive impairments in LDL receptor knockout mice: relevance of cortico-cerebral mitochondrial dysfunction and oxidative stress
J Oliveira, MA Hort, EL Moreira, V Glaser, RM Ribeiro-do-Valle, RD Prediger, M Farina, A Latini, AF Bem |
Neuroscience | 2011 |
|
The LDLR deficient mouse as a model for aortic calcification and quantification by micro-computed tomography
Z Awan, M Denis, D Bailey, A Giaid, A Prat, D Goltzman, NG Seidah, J Genest |
Atherosclerosis | 2011 |
|
Middle Cerebral Artery Occlusion Model in Rodents: Methods and Potential Pitfalls
F Liu, LD McCullough |
Journal of Biomedicine and Biotechnology | 2011 |
|
Distinct Characteristics of Circulating Vascular Endothelial Growth Factor-A and C Levels in Human Subjects
H Wada, S Ura, S Kitaoka, N Satoh-Asahara, T Horie, K Ono, T Takaya, R Takanabe-Mori, M Akao, M Abe, T Morimoto, T Murayama, M Yokode, M Fujita, A Shimatsu, K Hasegawa |
PloS one | 2011 |
|
Identification of Soat1 as a Quantitative Trait Locus Gene on Mouse Chromosome 1 Contributing to Hyperlipidemia
Z Lu, Z Yuan, T Miyoshi, Q Wang, Z Su, CC Chang, W Shi |
PloS one | 2011 |
|
Isoform-specific inhibitors of ACATs: recent advances and promising developments
T Ohshiro, H Tomoda |
Future Medicinal Chemistry | 2011 |
|
Adrenalectomy stimulates the formation of initial atherosclerotic lesions: Reversal by adrenal transplantation
RJ van der Sluis, GH van Puijvelde, TJ van Berkel, M Hoekstra |
Atherosclerosis | 2011 |
|
Familial hypercholesterolemia and triglyceride metabolism
GD Kolovou, PM Kostakou, KK Anagnostopoulou |
International Journal of Cardiology | 2011 |
|
Murine Norovirus Increases Atherosclerotic Lesion Size and Macrophages in Ldlr−/− Mice
J Paik, Y Fierce, PO Mai, SR Phelps, T McDonald, P Treuting, R Drivdahl, T Brabb, R LeBoeuf, KD O'Brien, L Maggio-Price |
Comparative medicine | 2011 |
|
Plasma lipid profiling across species for the identification of optimal animal models of human dyslipidemia
W Yin, E Carballo-Jane, DG McLaren, VH Mendoza, K Gagen, NS Geoghagen, LA McNamara, JN Gorski, GJ Eiermann, A Petrov, M Wolff, X Tong, LC Wilsie, TE Akiyama, J Chen, A Thankappan, J Xue, X Ping, G Andrews, LA Wickham, CL Gai, T Trinh, AA Kulick, MJ Donnelly, GO Voronin, R Rosa, AM Cumiskey, K Bekkari, LJ Mitnaul, O Puig, F Chen, R Raubertas, PH Wong, BC Hansen, KS Koblan, TP Roddy, BK Hubbard, AM Strack |
Journal of lipid research | 2011 |
|
Maternal-fetal transfer and metabolism of vitamin A and its precursor β-carotene in the developing tissues
E Spiegler, YK Kim, L Wassef, V Shete, L Quadro |
Biochimica et Biophysica Acta | 2011 |
|
Identification of differentially expressed proteins in blood plasma of control and cigarette smoke-exposed mice by 2-D DIGE/MS
AK Tewari, A Popova-Butler, MA El-Mahdy, JL Zweier |
PROTEOMICS | 2011 |
|
Lack of LDL Receptor Enhances Amyloid Deposition and Decreases Glial Response in an Alzheimer's Disease Mouse Model
L Katsouri, S Georgopoulos, ML Block |
PloS one | 2011 |
|
Biophysical Analysis of Apolipoprotein E3 Variants Linked with Development of Type III Hyperlipoproteinemia
D Georgiadou, A Chroni, A Vezeridis, VI Zannis, E Stratikos, B Kobe |
PloS one | 2011 |
|
Effects of macrophage-specific adiponectin expression on lipid metabolism in vivo
N Luo, X Wang, BH Chung, MH Lee, RL Klein, WT Garvey, Y Fu |
American journal of physiology. Endocrinology and metabolism | 2011 |
|
Dietary fat impacts fetal growth and metabolism: uptake of chylomicron remnant core lipids by the placenta
SL Rebholz, KT Burke, Q Yang, P Tso, LA Woollett |
American journal of physiology. Endocrinology and metabolism | 2011 |
|
siRNA-induced liver ApoB knockdown lowers serum LDL-cholesterol in a mouse model with human-like serum lipids
M Tadin-Strapps, LB Peterson, AM Cumiskey, RL Rosa, VH Mendoza, J Castro-Perez, O Puig, L Zhang, WR Strapps, S Yendluri, L Andrews, V Pickering, J Rice, L Luo, Z Chen, S Tep, B Ason, EP Somers, AB Sachs, SR Bartz, J Tian, J Chin, BK Hubbard, KK Wong, LJ Mitnaul |
Journal of lipid research | 2011 |
|
Mechanisms of Urokinase Plasminogen Activator (uPA)-mediated Atherosclerosis: ROLE OF THE uPA RECEPTOR AND S100A8/A9 PROTEINS
SD Farris, JH Hu, R Krishnan, I Emery, T Chu, L Du, M Kremen, HL Dichek, E Gold, SA Ramsey, DA Dichek |
The Journal of biological chemistry | 2011 |
|
Trypanosoma cruzi Utilizes the Host Low Density Lipoprotein Receptor in Invasion
F Nagajyothi, LM Weiss, DL Silver, MS Desruisseaux, PE Scherer, J Herz, HB Tanowitz, J Raper |
PLoS neglected tropical diseases | 2011 |
|
ApoB100/LDLR-/- Hypercholesterolaemic Mice as a Model for Mild Cognitive Impairment and Neuronal Damage
C Ramírez, S Sierra, I Tercero, JA Vázquez, A Pineda, T Manrique, JS Burgos, T Ikezu |
PloS one | 2011 |
|
Replication of Putative Susceptibility Loci from Genome-Wide Association Studies Associated with Coronary Atherosclerosis in Chinese Han Population
F Xie, X Chu, H Wu, W Sun, M Shen, L Yang, Y Wang, Y Wang, J Shi, W Huang, YQ Song |
PloS one | 2011 |
|
Development of Apolipoprotein E–Deficient Mice
N Maeda |
Arteriosclerosis, thrombosis, and vascular biology | 2011 |
|
Hyperlipidemia in Primary Care
MJ Sorrentino |
2011 | |
|
LXR promotes maximal egress of monocyte-derived cells from mouse aortic plaques during atherosclerosis regression
Jonathan Feig, Ines Pineda-Torra, Marie Sanson, Michelle Bradley, Yuliya Vengrenyuk, Dushun Bogunovic, Emmanuel Gautier, Daniel Rubinstein, Cynthia Hong, Jianhua Liu, Nico van Rooijen, Nina Bhardwaj, Michael Garabedian, Peter Tontonoz, Edward A. Fisher |
Journal of Clinical Investigation | 2010 |
|
No reduction of atherosclerosis in C-reactive protein (CRP)-deficient mice
D Teupser, O Weber, TN Rao, K Sass, J Thiery, HJ Fehling |
The Journal of biological chemistry | 2010 |
|
Myeloid differentiation factor 88 (MyD88)-deficiency increases risk of diabetes in mice
T Hosoi, S Yokoyama, S Matsuo, S Akira, K Ozawa |
PloS one | 2010 |
|
Mouse models of the metabolic syndrome
AJ Kennedy, KL Ellacott, VL King, AH Hasty |
Disease models & mechanisms | 2010 |
|
Lipoprotein receptors--an evolutionarily ancient multifunctional receptor family
M Dieckmann, MF Dietrich, J Herz |
Biological Chemistry | 2010 |
|
Transgenic overexpression of pregnancy-associated plasma protein-A in murine arterial smooth muscle accelerates atherosclerotic lesion development
CA Conover, MA Mason, LK Bale, SC Harrington, M Nyegaard, C Oxvig, MT Overgaard |
American journal of physiology. Heart and circulatory physiology | 2010 |
|
Gene therapy for dyslipidemia: a review of gene replacement and gene inhibition strategies
SH Kassim, JM Wilson, DJ Rader |
Clinical Lipidology | 2010 |
|
Egr-1 deficiency in bone marrow-derived cells reduces atherosclerotic lesion formation in a hyperlipidaemic mouse model
C Albrecht, MR Preusch, G Hofmann, S Morris-Rosenfeld, E Blessing, ME Rosenfeld, HA Katus, F Bea |
Cardiovascular Research | 2010 |
|
Hypercholesterolemia-Induced Erectile Dysfunction: Endothelial Nitric Oxide Synthase (eNOS) Uncoupling in the Mouse Penis by NAD(P)H Oxidase
B Musicki, T Liu, GA Lagoda, TD Strong, SF Sezen, JM Johnson, AL Burnett |
The Journal of Sexual Medicine | 2010 |
|
Ldlr−/− Mice Display Decreased Susceptibility to Western-Type Diet-Induced Obesity Due to Increased Thermogenesis
YF Ngai, WL Quong, MB Glier, MM Glavas, SL Babich, SM Innis, TJ Kieffer, WT Gibson |
Endocrinology | 2010 |
|
Inflammation and the Osteogenic Regulation of Vascular Calcification: A Review and Perspective
JS Shao, SL Cheng, J Sadhu, DA Towler |
Hypertension | 2010 |
|
SIRT1 decreases Lox-1-mediated foam cell formation in atherogenesis
S Stein, C Lohmann, N Schäfer, J Hofmann, L Rohrer, C Besler, KM Rothgiesser, B Becher, MO Hottiger, J Borén, MW McBurney, U Landmesser, TF Lüscher, CM Matter |
European Heart Journal | 2010 |
|
Targeted deletion of the 9p21 non-coding coronary artery disease risk interval in mice
A Visel, Y Zhu, D May, V Afzal, E Gong, C Attanasio, MJ Blow, JC Cohen, EM Rubin, LA Pennacchio |
Nature | 2010 |
|
Activation of Vascular Smooth Muscle Parathyroid Hormone Receptor Inhibits Wnt/β-Catenin Signaling and Aortic Fibrosis in Diabetic Arteriosclerosis
SL Cheng, JS Shao, LR Halstead, K Distelhorst, O Sierra, DA Towler |
Circulation research | 2010 |
|
Epistasis contributes to the genetic buffering of plasma HDL cholesterol in mice
RH Li, GA Churchill |
Physiological genomics | 2010 |
|
Lack of Association Between Adiponectin Levels and Atherosclerosis in Mice
AR Nawrocki, SM Hofmann, D Teupser, JE Basford, JL Durand, LA Jelicks, CW Woo, G Kuriakose, SM Factor, HB Tanowitz, DY Hui, I Tabas, PE Scherer |
Arteriosclerosis, thrombosis, and vascular biology | 2010 |
|
LDLR-Gene therapy for familial hypercholesterolaemia: problems, progress, and perspectives
FA Al-Allaf, C Coutelle, SN Waddington, AL David, R Harbottle, M Themis |
International archives of medicine | 2010 |
|
Animal models of ischemic stroke. Part one: modeling risk factors
M Bacigaluppi, G Comi, DM Hermann |
The open neurology journal | 2010 |
|
Cholesterol efflux via ATP-binding cassette transporter A1 (ABCA1) and cholesterol uptake via the LDL receptor influences cholesterol-induced impairment of beta cell function in mice
JK Kruit, PH Kremer, L Dai, R Tang, P Ruddle, W Haan, LR Brunham, CB Verchere, MR Hayden |
Diabetologia | 2010 |
|
Atherosclerotic lesions in mouse and man: is it the same disease?
JF Bentzon, E Falk |
Current Opinion in Lipidology | 2010 |
|
Recent insights into cerebral cavernous malformations: animal models of CCM and the human phenotype
AC Chan, DY Li, MJ Berg, KJ Whitehead |
FEBS Journal | 2010 |
|
HDL biogenesis and functions: Role of HDL quality and quantity in atherosclerosis
EM Tsompanidi, MS Brinkmeier, EH Fotiadou, SM Giakoumi, KE Kypreos |
Atherosclerosis | 2010 |
|
The Beneficial Effects α-Cyclodextrin on Blood Lipids and Weight Loss in Healthy Humans
KB Comerford, JD Artiss, KL Jen, SE Karakas |
Obesity | 2010 |
|
Reduction of endoplasmic reticulum stress—A novel mechanism of action of statins in the protection against atherosclerosis
I Breder, A Coope, AP Arruda, D Razolli, M Milanski, GG Dorighello, HC de Oliveira, LA Velloso |
Atherosclerosis | 2010 |
|
The role of fibrinolytic factors in atherosclerosis − findings in gene altered mice −
T IWAKI |
Japanese Journal of Thrombosis and Hemostasis | 2010 |
|
Inflammatory cell recruitment in cardiovascular disease: murine models and potential clinical applications
E McNeill, KM Channon, DR Greaves |
Clinical Science | 2010 |
|
The helix bundle: a reversible lipid binding motif
V Narayanaswami, RS Kiss, PM Weers |
Comparative biochemistry and physiology. Part A, Molecular & integrative physiology | 2010 |
|
ApoE-/- PGC-1α-/- mice display reduced IL-18 levels and do not develop enhanced atherosclerosis
S Stein, C Lohmann, C Handschin, E Stenfeldt, J Borén, TF Lüscher, CM Matter |
PloS one | 2010 |
|
How does diabetes accelerate Alzheimer disease pathology?
C Sims-Robinson, B Kim, A Rosko, EL Feldman |
Nature reviews. Neurology | 2010 |
|
DIFFERENTIAL IMPACT OF FAMILIAL HYPERCHOLESTEROLEMIA AND COMBINED HYPERLIPIDEMIA ON VASCULAR WALL AND NETWORK REMODELING IN MICE
PA Stapleton, AG Goodwill, ME James, AC D'Audiffret, JC Frisbee |
Microcirculation (New York, N.Y. : 1994) | 2010 |
|
Effect of transglutaminase 2 (TG2) deficiency on atherosclerotic plaque stability in the apolipoprotein E deficient mouse
H Williams, RJ Pease, LM Newell, PA Cordell, RM Graham, MT Kearney, CL Jackson, PJ Grant |
Atherosclerosis | 2010 |
|
Amelioration of nephropathy with apoA-1 mimetic peptide in apoE-deficient mice
ND Vaziri, HJ Kim, H Moradi, F Farmand, K Navab, M Navab, S Hama, AM Fogelman, Y Quiroz, B Rodriguez-Iturbe |
Nephrology Dialysis Transplantation | 2010 |
|
Current Topics in Membranes
TC Wagenknecht, Z Liu |
Structure and Function of Calcium Release Channels | 2010 |
|
Induced pluripotent stem cells: A new era for hepatology
S Asgari, B Pournasr, GH Salekdeh, A Ghodsizadeh, M Ott, H Baharvand |
Journal of Hepatology | 2010 |
|
Natural Killer Cells
D Mavilio, A Hosmalin, D Scott-Algara |
Natural Killer Cells | 2010 |
|
LDLR Expression and Localization Are Altered in Mouse and Human Cell Culture Models of Alzheimer's Disease
JF Abisambra, T Fiorelli, J Padmanabhan, P Neame, I Wefes, H Potter, CX Gong |
PloS one | 2010 |
|
Aspirin resistance with genetic dyslipidemia: contribution of vascular thromboxane generation
JC Frisbee, AG Goodwill, PA Stapleton, SJ Frisbee, AC d'Audiffret |
Physiological genomics | 2010 |
|
Syndecan-1, the Primary Heparan Sulfate Proteoglycan Mediating Hepatic Triglyceride-Rich Lipoprotein Clearance In Vivo
Kristin I. Stanford, Joseph R. Bishop, Erin M. Foley, Jon C. Gonzalez, Ingrid R. Niesman, Joseph L. Witztum, Jeffrey D. Esko |
Journal of Clinical Investigation | 2009 |
|
Pulmonary ozone exposure induces vascular dysfunction, mitochondrial damage, and atherogenesis
GC Chuang, Z Yang, DG Westbrook, M Pompilius, CA Ballinger, CR White, DM Krzywanski, EM Postlethwait, SW Ballinger |
American journal of physiology. Lung cellular and molecular physiology | 2009 |
|
LXR-SREBP-1c-phospholipid transfer protein axis controls very low density lipoprotein (VLDL) particle size
H Okazaki, JL Goldstein, MS Brown, G Liang |
The Journal of biological chemistry | 2009 |
|
LRP1 regulates architecture of the vascular wall by controlling PDGFRbeta-dependent phosphatidylinositol 3-kinase activation
L Zhou, Y Takayama, P Boucher, MD Tallquist, J Herz |
PloS one | 2009 |
|
Pulmonary surfactant: an immunological perspective
ZC Chroneos, Z Sever-Chroneos, VL Shepherd |
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology | 2009 |
|
Innate and adaptive immunity in atherosclerosis
RR Packard, AH Lichtman, P Libby |
Seminars in Immunopathology | 2009 |
|
Vascular effects of a low-carbohydrate high-protein diet
SY Foo, ER Heller, J Wykrzykowska, CJ Sullivan, JJ Manning-Tobin, KJ Moore, RE Gerszten, A Rosenzweig |
Proceedings of the National Academy of Sciences | 2009 |
|
Type 2 scavenger receptor CD36 in platelet activation: the role of hyperlipemia and oxidative stress
RL Silverstein |
Clinical Lipidology | 2009 |
|
Ablation of Neutral Cholesterol Ester Hydrolase 1 Accelerates Atherosclerosis
M Sekiya, J Osuga, S Nagashima, T Ohshiro, M Igarashi, H Okazaki, M Takahashi, F Tazoe, T Wada, K Ohta, M Takanashi, M Kumagai, M Nishi, S Takase, N Yahagi, H Yagyu, K Ohashi, R Nagai, T Kadowaki, Y Furukawa, S Ishibashi |
Cell Metabolism | 2009 |
|
Mouse oocyte control of granulosa cell development and function: paracrine regulation of cumulus cell metabolism
YQ Su, K Sugiura, JJ Eppig |
Seminars in reproductive medicine | 2009 |
|
Despite Antiatherogenic Metabolic Characteristics, SCD1-Deficient Mice Have Increased Inflammation and Atherosclerosis
ML MacDonald, M van Eck, RB Hildebrand, BW Wong, N Bissada, P Ruddle, A Kontush, H Hussein, MA Pouladi, MJ Chapman, C Fievet, TJ van Berkel, B Staels, BM McManus, MR Hayden |
Arteriosclerosis, thrombosis, and vascular biology | 2009 |
|
StAR overexpression decreases serum and tissue lipids in apolipoprotein E-deficient mice
Y Ning, L Xu, S Ren, WM Pandak, S Chen, L Yin |
Lipids | 2009 |
|
Molecular Mechanisms of Hepatic Steatosis and Insulin Resistance in the AGPAT2-Deficient Mouse Model of Congenital Generalized Lipodystrophy
VA Cortés, DE Curtis, S Sukumaran, X Shao, V Parameswara, S Rashid, AR Smith, J Ren, V Esser, RE Hammer, AK Agarwal, JD Horton, A Garg |
Cell Metabolism | 2009 |
|
Loss of PDZK1 causes coronary artery occlusion and myocardial infarction in Paigen diet-fed apolipoprotein E deficient mice
A Yesilaltay, K Daniels, R Pal, M Krieger, O Kocher |
PloS one | 2009 |
|
Altered expression of genes functioning in lipid homeostasis is associated with lipid deposition in NOD mouse lacrimal gland
K Wu, C Joffre, X Li, M MacVeigh-Aloni, M Hom, J Hwang, C Ding, S Gregoire, L Bretillon, JF Zhong, SF Hamm-Alvarez |
Experimental Eye Research | 2009 |
|
Absence of p55 TNF receptor reduces atherosclerosis, but has no major effect on angiotensin II induced aneurysms in LDL receptor deficient mice
S Xanthoulea, M Thelen, C Pöttgens, MJ Gijbels, E Lutgens, MP de Winther |
PloS one | 2009 |
|
Connexins in Vascular Physiology and Pathology
AC Brisset, BE Isakson, BR Kwak |
Antioxidants & Redox Signaling | 2009 |
|
Food-entrained rhythmic expression of apolipoprotein E expression in the hypothalamus of rats
L Shen, K Carey, DQ Wang, SC Woods, M Liu |
Brain Research | 2009 |
|
Long-term Physiologically Regulated Expression of the Low-density Lipoprotein Receptor In Vivo Using Genomic DNA Mini-gene Constructs
OC Hibbitt, E McNeil, MM Lufino, L Seymour, K Channon, R Wade-Martins |
Molecular Therapy | 2009 |
|
Connexins participate in the initiation and progression of atherosclerosis
S Morel, L Burnier, BR Kwak |
Seminars in Immunopathology | 2009 |
|
Atherosclerosis—An immune disease
GK Hansson |
Atherosclerosis | 2009 |
|
Apolipoprotein E knock-out and knock-in mice: atherosclerosis, metabolic syndrome, and beyond
AA Pendse, JM Arbones-Mainar, LA Johnson, MK Altenburg, N Maeda |
Journal of lipid research | 2009 |
|
Liver-specific loss of lipolysis-stimulated lipoprotein receptor triggers systemic hyperlipidemia in mice
P Narvekar, MB Diaz, A Krones-Herzig, U Hardeland, D Strzoda, S Stöhr, M Frohme, S Herzig |
Diabetes | 2009 |
|
Mclk1+/- mice are not resistant to the development of atherosclerosis
BG Hughes, S Hekimi |
Lipids in Health and Disease | 2009 |
|
A novel mouse model of in situ stenting
J Chamberlain, M Wheatcroft, N Arnold, H Lupton, DC Crossman, J Gunn, S Francis |
Cardiovascular Research | 2009 |
|
An apoA-I mimetic peptide increases LCAT activity in mice through increasing HDL concentration
X Chen, C Burton, X Song, L McNamara, A Langella, S Cianetti, CH Chang, J Wang |
International journal of biological sciences | 2009 |
|
Genomics and Cardiovascular Drug Development
AS Plump, PY Lum |
Journal of the American College of Cardiology | 2009 |
|
Absence of stearoyl-CoA desaturase-1 does not promote DSS-induced acute colitis
ML MacDonald, N Bissada, BA Vallance, MR Hayden |
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids | 2009 |
|
Escherichia coli lipopolysaccharide administration alters antioxidant profile during hypercholesterolemia
K Dutta, B Bishayi |
Indian Journal of Clinical Biochemistry | 2009 |
|
NMR-based metabolomics of urine for the atherosclerotic mouse model using apolipoprotein-E deficient mice
GC Leo, AL Darrow |
Magnetic Resonance in Chemistry | 2009 |
|
In vivo models of cardiac diseases: application to drug development and screening
H Rokutan, SD Anker, J Springer |
Expert Opinion on Drug Discovery | 2009 |
|
Pitfalls in the assessment of murine atherosclerosis
S Catanozi, JC Rocha, M Passarelli, FC Chiquito, EC Quintão, ER Nakandakare |
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas / Sociedade Brasileira de Biofisica ... [et al.] | 2009 |
|
Developmental programming of sex-dependent alterations in lipid metabolism: a role for long-term, sex-specific alterations in LDL-receptor expression . Focus on “Developmental programming of lipid metabolism and aortic vascular function in C57BL/6 mice: a novel study suggesting an involvement of LDL-receptor”
BT Alexander |
American Journal of Physiology - Regulatory, Integrative and Comparative Physiology | 2009 |
|
Observation of the density and size of cells in hippocampus and vascular lesion in thalamus of GFAP-apoE transgenic mice
KF Tang, L Cai, JN Zhou |
Neuroscience Bulletin | 2009 |
|
Novel cerebrovascular pathology in mice fed a high cholesterol diet
S Franciosi, MA Sosa, DF English, E Oler, T Oung, WG Janssen, RD Gasperi, J Schmeidler, DL Dickstein, C Schmitz, S Gandy, PR Hof, JD Buxbaum, G A |
Molecular Neurodegeneration | 2009 |
|
Niemann-Pick C1 (NPC1) serves an atheroprotective role through regulation of macrophage intracellular cholesterol trafficking
Jessie R. Zhang, Trey Coleman, S. Joshua Langmade, David E. Scherrer, Lindsay Lane, M. Hunter Lanier, Chu Feng, Mark S. Sands, Jean E. Schaffer, Clay F. Semenkovich, and Daniel S. Ory |
Journal of Clinical Investigation | 2008 |
|
LRP1 controls intracellular cholesterol storage and fatty acid synthesis through modulation of Wnt signaling
J Terrand, V Bruban, L Zhou, W Gong, ZE Asmar, P May, K Zurhove, P Haffner, C Philippe, E Woldt, RL Matz, C Gracia, D Metzger, J Auwerx, J Herz, P Boucher |
The Journal of biological chemistry | 2008 |
|
Anti-oxLDL antibody isotype levels, as potential markers for progressive atherosclerosis in APOE and APOECD40L mice
ML Smook, M Leeuwen, P Heeringa, JG Damoiseaux, R Theunissen, MJ Daemen, E Lutgens, JW Tervaert |
Clinical & Experimental Immunology | 2008 |
|
The IL-33/ST2 pathway: therapeutic target and novel biomarker
R Kakkar, RT Lee |
Nature Reviews Drug Discovery | 2008 |
|
Atheroprotective role of interleukin-6 in diet- and/or pathogen-associated atherosclerosis using an ApoE heterozygote murine model
M Madan, B Bishayi, M Hoge, S Amar |
Atherosclerosis | 2008 |
|
Absence of Hyperlipidemia in LDL Receptor-Deficient Mice Having Apolipoprotein B100 Without the Putative Receptor-Binding Sequences
LA Johnson, MK Altenburg, RL Walzem, LT Scanga, N Maeda |
Arteriosclerosis, thrombosis, and vascular biology | 2008 |
|
Monocyte-endothelial cell interactions in the development of atherosclerosis
J Mestas, K Ley |
Trends in Cardiovascular Medicine | 2008 |
|
Altered Gene Expression in Early Atherosclerosis Is Blocked by Low Level Apolipoprotein E
Y Ma, CC Malbon, DL Williams, FE Thorngate, G Pockley |
PloS one | 2008 |
|
Dietary alpha-cyclodextrin lowers low-density lipoprotein cholesterol and alters plasma fatty acid profile in low-density lipoprotein receptor knockout mice on a high-fat diet
EM Wagner, KL Jen, JD Artiss, AT Remaley |
Metabolism: clinical and experimental | 2008 |
|
Inhibition of intestinal absorption of cholesterol by ezetimibe or bile acids by SC-435 alters lipoprotein metabolism and extends the lifespan of SR-BI/apoE double knockout mice
A Braun, A Yesilaltay, S Acton, KO Broschat, ES Krul, N Napawan, N Stagliano, M Krieger |
Atherosclerosis | 2008 |
|
Oocyte regulation of metabolic cooperativity between mouse cumulus cells and oocytes: BMP15 and GDF9 control cholesterol biosynthesis in cumulus cells
YQ Su, K Sugiura, K Wigglesworth, MJ O'Brien, JP Affourtit, SA Pangas, MM Matzuk, JJ Eppig |
Development (Cambridge, England) | 2008 |
|
Plasma PCSK9 preferentially reduces liver LDL receptors in mice
A Grefhorst, MC McNutt, TA Lagace, JD Horton |
Journal of lipid research | 2008 |
|
Animal and cellular models for hypolipidemic drugs
A Cignarella |
Expert Opinion on Drug Discovery | 2008 |
|
MAPK signalling in cardiovascular health and disease: molecular mechanisms and therapeutic targets
AJ Muslin |
Clinical Science | 2008 |
|
Influence of PDZK1 on lipoprotein metabolism and atherosclerosis
O Kocher, A Yesilaltay, CH Shen, S Zhang, K Daniels, R Pal, J Chen, M Krieger |
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease | 2008 |
|
Toll-like receptor 2 plays a critical role in the progression of atherosclerosis that is independent of dietary lipids
X Liu, T Ukai, H Yumoto, M Davey, S Goswami, FC 3rd, CA Genco |
Atherosclerosis | 2008 |
|
Mast cells: pivotal players in cardiovascular diseases
I Bot, TJ van Berkel, EA Biessen |
Current cardiology reviews | 2008 |
|
Apolipoprotein E predisposes to obesity and related metabolic dysfunctions in mice
I Karagiannides, R Abdou, A Tzortzopoulou, PJ Voshol, KE Kypreos |
FEBS Journal | 2008 |
|
RAGE mediates oxidized LDL-induced pro-inflammatory effects and atherosclerosis in non-diabetic LDL receptor-deficient mice
L Sun, T Ishida, T Yasuda, Y Kojima, T Honjo, Y Yamamoto, H Yamamoto, S Ishibashi, K Hirata, Y Hayashi |
Cardiovascular Research | 2008 |
|
Novartis Foundation Symposia
EJ Campbell |
Ciba Foundation Symposium 44 - Research and Medical Practice: Their Interaction | 2008 |
|
Rapid regression of atherosclerosis: insights from the clinical and experimental literature
KJ Williams, JE Feig, EA Fisher |
Nature Clinical Practice Cardiovascular Medicine | 2008 |
|
Impact of lipoproteins on the biological activity and disposition of hydrophobic drugs: implications for drug discovery
KM Wasan, DR Brocks, SD Lee, K Sachs-Barrable, SJ Thornton |
Nature Reviews Drug Discovery | 2008 |
|
High cholesterol-induced neuroinflammation and amyloid precursor protein processing correlate with loss of working memory in mice
L Thirumangalakudi, A Prakasam, R Zhang, H Bimonte-Nelson, K Sambamurti, MS Kindy, NR Bhat |
Journal of Neurochemistry | 2008 |
|
Multiple receptors involved in human rhinovirus attachment to live cells
C Rankl, F Kienberger, L Wildling, J Wruss, HJ Gruber, D Blaas, P Hinterdorfer |
Proceedings of the National Academy of Sciences | 2008 |
|
Increased locomotor activity in mice lacking the low-density lipoprotein receptor
GA Elder, A Ragnauth, N Dorr, S Franciosi, J Schmeidler, V Haroutunian, JD Buxbaum |
Behavioural Brain Research | 2008 |
|
Plasma carboxyl ester lipase activity modulates apolipoprotein B–containing lipoprotein metabolism in a transgenic mouse model
L Li, W Weng, EH Harrison, EA Fisher |
Metabolism | 2008 |
|
Dietary cholesterol, rather than liver steatosis, leads to hepatic inflammation in hyperlipidemic mouse models of nonalcoholic steatohepatitis
K Wouters, PJ van Gorp, V Bieghs, MJ Gijbels, H Duimel, D Lütjohann, A Kerksiek, R Kruchten, N Maeda, B Staels, M Bilsen, R Shiri-Sverdlov, MH Hofker |
Hepatology | 2008 |
|
Adenoviral low density lipoprotein receptor attenuates progression of atherosclerosis and decreases tissue cholesterol levels in a murine model of familial hypercholesterolemia
F Jacobs, EV Craeyveld, Y Feng, J Snoeys, BD Geest |
Atherosclerosis | 2008 |
|
p55 Tumour necrosis factor receptor in bone marrow-derived cells promotes atherosclerosis development in low-density lipoprotein receptor knock-out mice
S Xanthoulea, MJ Gijbels, I der Made, H Mujcic, M Thelen, MN Vergouwe, MH Ambagts, MH Hofker, MP de Winther |
Cardiovascular Research | 2008 |
|
Mangifera indica L. extract (Vimang®) and its main polyphenol mangiferin prevent mitochondrial oxidative stress in atherosclerosis-prone hypercholesterolemic mouse
GL Pardo-Andreu, BA Paim, RF Castilho, JA Velho, R Delgado, AE Vercesi, HC Oliveira |
Pharmacological Research | 2008 |
|
Low-density lipoproteins from embryonic cerebrospinal fluid are required for neural differentiation
C Parada, JC Escolà-Gil, D Bueno |
Journal of Neuroscience Research | 2008 |
|
Cholesterol Reduction and Atherosclerosis Inhibition by Bezafibrate in Low-Density Lipoprotein Receptor Knockout Mice
T INABA, H YAGYU, N ITABASHI, F TAZOE, N FUJITA, S NAGASHIMA, K OKADA, M OKAZAKI, Y FURUKAWA, S ISHIBASHI |
Hypertension Research | 2008 |
|
Oxidative stress in hypercholesterolemic LDL (low-density lipoprotein) receptor knockout mice is associated with low content of mitochondrial NADP-linked substrates and is partially reversed by citrate replacement
BA Paim, JA Velho, RF Castilho, HC Oliveira, AE Vercesi |
Free radical biology & medicine | 2008 |
|
Antiatherogenic property of triterpenoids-enriched extract from the aerial parts of Salvia miltiorrhiza
Q Zhang, Z Chang, J Yang, Q Wang |
Phytotherapy Research | 2008 |
|
Cardiovascular roles of nitric oxide: a review of insights from nitric oxide synthase gene disrupted mice
VW Liu, PL Huang |
Cardiovascular Research | 2008 |
|
ApoB100-LDL acts as a metabolic signal from liver to peripheral fat causing inhibition of lipolysis in adipocytes
J Skogsberg, A Dicker, M Rydén, G Aström, R Nilsson, H Bhuiyan, S Vitols, A Mairal, D Langin, P Alberts, E Walum, J Tegnér, A Hamsten, P Arner, J Björkegren |
PloS one | 2008 |
|
Increased arachidonic acid-induced thromboxane generation impairs skeletal muscle arteriolar dilation with genetic dyslipidemia
AG Goodwill, PA Stapleton, ME James, AC D'Audiffret, JC Frisbee |
Microcirculation (New York, N.Y. : 1994) | 2008 |
|
Sex specific gene regulation and expression QTLs in mouse macrophages from a strain intercross
JM Bhasin, E Chakrabarti, DQ Peng, A Kulkarni, X Chen, JD Smith |
PloS one | 2008 |
|
Intimal hyperplasia in murine models
DY Hui |
Current drug targets | 2008 |
|
Lipoprotein size and susceptibility to atherosclerosis--insights from genetically modified mouse models
MM Véniant, AP Beigneux, A Bensadoun, LG Fong, SG Young |
Current drug targets | 2008 |
|
Influence of low-density lipoprotein (LDL) receptor on lipid composition, inflammation and parasitism during Toxoplasma gondii infection
LR Portugal, LR Fernandes, VS Pedroso, HC Santiago, RT Gazzinelli, JI Alvarez-Leite |
Microbes and Infection | 2008 |
|
OF CARDIOVASCULAR ILLNESS AND DIVERSITY OF BIOLOGICAL RESPONSE
PJ Goldschmidt-Clermont, C Dong, M West, DM Seo |
Trends in Cardiovascular Medicine | 2008 |
|
The hemostasis system in murine atherosclerosis
T Iwaki, VA Ploplis, FJ Castellino |
Current drug targets | 2008 |
|
ApoB100-LDL Acts as a Metabolic Signal from Liver to Peripheral Fat Causing Inhibition of Lipolysis in Adipocytes
J Skogsberg, A Dicker, M Rydén, G Åström, R Nilsson, H Bhuiyan, S Vitols, A Mairal, D Langin, P Alberts, E Walum, J Tegnér, A Hamsten, P Arner, J Björkegren, A Bartolomucci |
PloS one | 2008 |
|
Phospholipid transfer protein deficiency ameliorates diet-induced hypercholesterolemia and inflammation in mice
L Shelly, L Royer, T Sand, H Jensen, Y Luo |
Journal of lipid research | 2008 |
|
Apolipoprotein E knock-out and knock-in mice: atherosclerosis, metabolic syndrome, and beyond: Fig. 1
AA Pendse, JM Arbones-Mainar, LA Johnson, MK Altenburg, N Maeda |
Journal of lipid research | 2008 |
|
Plasma PCSK9 preferentially reduces liver LDL receptors in mice
A Grefhorst, MC McNutt, TA Lagace, JD Horton |
Journal of lipid research | 2008 |
|
Generation and characterization of two novel mouse models exhibiting the phenotypes of the metabolic syndrome: Apob48 −/− Lep ob/ob mice devoid of ApoE or Ldlr
DJ Lloyd, J McCormick, J Helmering, KW Kim, M Wang, P Fordstrom, SA Kaufman, RA Lindberg, MM Véniant |
American journal of physiology. Endocrinology and metabolism | 2008 |
|
An Inducible and Reversible Mouse Genetic Rescue System
H Zeng, K Horie, L Madisen, MN Pavlova, G Gragerova, AD Rohde, BA Schimpf, Y Liang, E Ojala, F Kramer, P Roth, O Slobodskaya, I Dolka, EA Southon, L Tessarollo, KE Bornfeldt, A Gragerov, GN Pavlakis, GA Gaitanaris, D Beier |
PLoS genetics | 2008 |
|
A new mouse mutant for the LDL receptor identified using ENU mutagenesis
KL Svenson, N Ahituv, RS Durgin, H Savage, PA Magnani, O Foreman, B Paigen, LL Peters |
Journal of lipid research | 2008 |
|
Biomarkers related to aging in human populations
Eileen Crimmins, Sarinnapha Vasunilashorn, Jung Ki Kim, Dawn Alley |
Advances in Clinical Chemistry | 2008 |
|
Sourcebook of Models for Biomedical Research
PM Conn |
2008 | |
|
Preservation of VLDL remnant clearance attenuates the phenotype of autosomal recessive hypercholesterolemia
Christopher Jones, Rita Garuti1, Peter Michaely, Wei-Ping Li, Nobuyo Maeda, Jonathan C. Cohen, Joachim Herz, and Helen H. Hobbs |
Journal of Clinical Investigation | 2007 |
|
Liver heparan sulfate proteoglycans mediate clearance of triglyceride-rich lipoproteins independently of LDL receptor family members
Jennifer M. MacArthur Joseph R. Bishop Kristin I. Stanford Lianchun Wang André Bensadoun Joseph L. Witztum Jeffrey D. Esko |
Journal of Clinical Investigation | 2007 |
|
Detecting and assessing macrophages in vivo to evaluate atherosclerosis noninvasively using molecular MRI
V Amirbekian, MJ Lipinski, KC Briley-Saebo, S Amirbekian, JG Aguinaldo, DB Weinreb, E Vucic, JC Frias, F Hyafil, V Mani, EA Fisher, ZA Fayad |
Proceedings of the National Academy of Sciences | 2007 |
|
Dyslipidemia inhibits Toll-like receptor-induced activation of CD8alpha-negative dendritic cells and protective Th1 type immunity
AT Shamshiev, F Ampenberger, B Ernst, L Rohrer, BJ Marsland, M Kopf |
Journal of Experimental Medicine | 2007 |
|
Chronic intermittent hypoxia induces atherosclerosis
V Savransky, A Nanayakkara, J Li, S Bevans, PL Smith, A Rodriguez, VY Polotsky |
American journal of respiratory and critical care medicine | 2007 |
|
The healing myocardium sequentially mobilizes two monocyte subsets with divergent and complementary functions
M Nahrendorf, FK Swirski, E Aikawa, L Stangenberg, T Wurdinger, JL Figueiredo, P Libby, R Weissleder, MJ Pittet |
Journal of Experimental Medicine | 2007 |
|
Human C-reactive protein slows atherosclerosis development in a mouse model with human-like hypercholesterolemia
A Kovacs, P Tornvall, R Nilsson, J Tegnér, A Hamsten, J Björkegren |
Proceedings of the National Academy of Sciences | 2007 |
|
Absence of stearoyl-CoA desaturase-1 ameliorates features of the metabolic syndrome in LDLR-deficient mice
ML MacDonald, RR Singaraja, N Bissada, P Ruddle, R Watts, JM Karasinska, WT Gibson, C Fievet, JE Vance, B Staels, MR Hayden |
Journal of lipid research | 2007 |
|
Diabetes and arterial extracellular matrix changes in a porcine model of atherosclerosis
TO McDonald, RG Gerrity, C Jen, HJ Chen, K Wark, TN Wight, A Chait, KD O'Brien |
Journal of Histochemistry & Cytochemistry | 2007 |
|
Loss of apolipoprotein E exacerbates the neonatal lethality of the Smith-Lemli-Opitz syndrome mouse
C Solcà, B Pandit, H Yu, GS Tint, SB Patel |
Molecular Genetics and Metabolism | 2007 |
|
Role of High-Density Lipoprotein and Scavenger Receptor B Type I in the Promotion of Endothelial Repair
C Mineo, PW Shaul |
Trends in Cardiovascular Medicine | 2007 |
|
LRP1 functions as an atheroprotective integrator of TGFbeta and PDFG signals in the vascular wall: implications for Marfan syndrome
P Boucher, WP Li, RL Matz, Y Takayama, J Auwerx, RG Anderson, J Herz |
PloS one | 2007 |
|
Handbook of Experimental Pharmacology
HH Bock, J Herz, P May |
Handbook of experimental pharmacology | 2007 |
|
Effects of vitamin E on oxidative stress and atherosclerosis in an obese hyperlipidemic mouse model
AH Hasty, ML Gruen, ES Terry, BK Surmi, RD Atkinson, L Gao, JD Morrow |
The Journal of Nutritional Biochemistry | 2007 |
|
TLR2 in murine atherosclerosis
PS Tobias, LK Curtiss |
Seminars in Immunopathology | 2007 |
|
Orally administered eicosapentaenoic acid reduces and stabilizes atherosclerotic lesions in ApoE-deficient mice
M Matsumoto, M Sata, D Fukuda, K Tanaka, M Soma, Y Hirata, R Nagai |
Atherosclerosis | 2007 |
|
The Cellular Trafficking of the Secretory Proprotein Convertase PCSK9 and Its Dependence on the LDLR
N Nassoury, DA Blasiole, AT Oler, S Benjannet, J Hamelin, V Poupon, PS McPherson, AD Attie, A Prat, NG Seidah |
Traffic | 2007 |
|
Liver X receptor activation enhances cholesterol loss from the brain, decreases neuroinflammation, and increases survival of the NPC1 mouse.
Repa JJ, Li H, Frank-Cannon TC, Valasek MA, Turley SD, Tansey MG, Dietschy JM |
The Journal of neuroscience : the official journal of the Society for Neuroscience | 2007 |
|
Anatomical differences and atherosclerosis in apolipoprotein E-deficient mice with 129/SvEv and C57BL/6 genetic backgrounds
N Maeda, L Johnson, S Kim, J Hagaman, M Friedman, R Reddick |
Atherosclerosis | 2007 |
|
Interleukin-4 Does Not Influence Development of Hypercholesterolemia or Angiotensin II-Induced Atherosclerotic Lesions in Mice
VL King, LA Cassis, A Daugherty |
The American Journal of Pathology | 2007 |
|
Cellular, molecular and clinical aspects of vitamin E on atherosclerosis prevention
A Munteanu, JM Zingg |
Molecular Aspects of Medicine | 2007 |
|
Combined Treatment With Sustained-Release Basic Fibroblast Growth Factor and Heparin Enhances Neovascularization in Hypercholesterolemic Mouse Hindlimb Ischemia
Y Arai, M Fujita, A Marui, K Hirose, H Sakaguchi, T Ikeda, Y Tabata, M Komeda |
Circulation Journal | 2007 |
|
Elevated plasma cholesterol does not affect brain A? in mice lacking the low-density lipoprotein receptor
GA Elder, JY Cho, DF English, S Franciosi, J Schmeidler, MA Sosa, RD Gasperi, EA Fisher, PM Mathews, V Haroutunian, JD Buxbaum |
Journal of Neurochemistry | 2007 |
|
Delivery and long-term expression of a 135 kbLDLR genomic DNA locusin vivo by hydrodynamic tail vein injection
OC Hibbitt, RP Harbottle, SN Waddington, CA Bursill, C Coutelle, KM Channon, R Wade-Martins |
The Journal of Gene Medicine | 2007 |
|
Plasma plasminogen activator inhibitor-1 level is not regulated by the hepatic low-density lipoprotein receptor-related protein
L Hu, N Bovenschen, LM Havekes, BJ van Vlijmen, JT Tamsma |
Journal of Thrombosis and Haemostasis | 2007 |
|
Mechanisms and optimization of in vivo delivery of lipophilic siRNAs
C Wolfrum, S Shi, KN Jayaprakash, M Jayaraman, G Wang, RK Pandey, KG Rajeev, T Nakayama, K Charrise, EM Ndungo, T Zimmermann, V Koteliansky, M Manoharan, M Stoffel |
Nature Biotechnology | 2007 |
|
Estrogen increases apoptosis in the arterial wall in a murine atherosclerosis model
E Seli, O Guzeloglu-Kayisli, UA Kayisli, G Kizilay, A Arici |
Fertility and Sterility | 2007 |
|
Residues Leu261, Trp264, and Phe265 account for apolipoprotein E-induced dyslipidemia and affect the formation of apolipoprotein E-containing high-density lipoprotein
K Drosatos, KE Kypreos, VI Zannis |
Biochemistry | 2007 |
|
Modification by acrolein, a component of tobacco smoke and age-related oxidative stress, mediates functional impairment of human apolipoprotein E
S Tamamizu-Kato, JY Wong, V Jairam, K Uchida, V Raussens, H Kato, JM Ruysschaert, V Narayanaswami |
Biochemistry | 2007 |
|
Impairment of endothelium-dependent relaxation of aortas and pulmonary arteries from spontaneously hyperlipidemic mice (Apodemus sylvaticus)
KM Ito, M Okayasu, C Koshimoto, A Shinohara, Y Asada, K Tsuchiya, T Sakamoto, K Ito |
Vascular Pharmacology | 2007 |
|
Effects of Isoflurane on Coronary Blood Flow Velocity in Young, Old, and ApoE−/− Mice Measured by Doppler Ultrasound
CJ Hartley, AK Reddy, S Madala, LH Michael, ML Entman, GE Taffet |
Ultrasound in Medicine & Biology | 2007 |
|
Post-Genomic Cardiology
J Marín-García, MJ Goldenthal, GW Moe |
Post-Genomic Cardiology | 2007 |
|
ADAMTS-4 and -8 are inflammatory regulated enzymes expressed in macrophage-rich areas of human atherosclerotic plaques
D Wågsäter, H Björk, C Zhu, J Björkegren, G Valen, A Hamsten, P Eriksson |
Atherosclerosis | 2007 |
|
LDL receptor deficiency results in decreased cell proliferation and presynaptic bouton density in the murine hippocampus
M Mulder, G Koopmans, G Wassink, GA Mansouri, ML Simard, LM Havekes, J Prickaerts, A Blokland |
Neuroscience Research | 2007 |
|
Diabetes and Arterial Extracellular Matrix Changes in a Porcine Model of Atherosclerosis
TO McDonald, RG Gerrity, C Jen, HJ Chen, K Wark, TN Wight, A Chait, KD O'Brien |
Journal of Histochemistry & Cytochemistry | 2007 |
|
LRP1 Functions as an Atheroprotective Integrator of TGFβ and PDGF Signals in the Vascular Wall: Implications for Marfan Syndrome
P Boucher, WP Li, RL Matz, Y Takayama, J Auwerx, RG Anderson, J Herz, M Hatakeyama |
PloS one | 2007 |
|
Mouse model of the metabolic syndrome: the quest continues
VY Polotsky |
Journal of applied physiology | 2007 |
|
Receptor-mediated and bulk-phase endocytosis cause macrophage and cholesterol accumulation in Niemann-Pick C disease
B Liu, C Xie, JA Richardson, SD Turley, JM Dietschy |
Journal of lipid research | 2007 |
|
The low density lipoprotein receptor is not necessary for maintaining mouse brain polyunsaturated fatty acid concentrations
CT Chen, DW Ma, JH Kim, HT Mount, RP Bazinet |
Journal of lipid research | 2007 |
|
Monounsaturated fatty acyl-coenzyme A is predictive of atherosclerosis in human apoB-100 transgenic, LDLr −/− mice
TA Bell, MD Wilson, K Kelley, JK Sawyer, LL Rudel |
Journal of lipid research | 2007 |
|
Altered mechanisms of endothelium-dependent dilation in skeletal muscle arterioles with genetic hypercholesterolemia
PA Stapleton, AG Goodwill, ME James, JC Frisbee |
American Journal of Physiology - Regulatory, Integrative and Comparative Physiology | 2007 |
|
Genetic variations and treatments that affect the lifespan of the NPC1 mouse
B Liu, H Li, JJ Repa, SD Turley, JM Dietschy |
Journal of lipid research | 2007 |
|
Effects of emulsified policosanols with different chain lengths on cholesterol metabolism in heterozygous LDL receptor-deficient mice
SP Dullens, RP Mensink, MC Bragt, AK Kies, J Plat |
Journal of lipid research | 2007 |
|
Expression of the Lyst beige mutation is atheroprotective in chow-fed apolipoprotein E-deficient mice
RJ Petrovan, Y Yuan, LK Curtiss |
Journal of lipid research | 2007 |
|
Vascular Biology Protocols
N Sreejayan, J Ren |
2007 | |
|
Lipoproteins and their receptors in embryonic development: more than cholesterol clearance
TE Willnow, A Hammes, S Eaton |
Development (Cambridge, England) | 2007 |
|
Haploinsufficiency in the PPARalpha and LDL receptor genes leads to gender- and age-specific obesity and hyperinsulinemia
E Sugiyama, N Tanaka, T Nakajima, Y Kamijo, S Yokoyama, Y Li, FJ Gonzalez, T Aoyama |
Biochemical and Biophysical Research Communications | 2006 |
|
Polyphenols stimulate AMP-activated protein kinase, lower lipids, and inhibit accelerated atherosclerosis in diabetic LDL receptor-deficient mice
M Zang, S Xu, KA Maitland-Toolan, A Zuccollo, X Hou, B Jiang, M Wierzbicki, TJ Verbeuren, RA Cohen |
Diabetes | 2006 |
|
Cytokines in Atherosclerosis: Pathogenic and Regulatory Pathways
A Tedgui |
Physiological reviews | 2006 |
|
Periodontal disease and systemic conditions: a bidirectional relationship
J Kim, S Amar |
Odontology / the Society of the Nippon Dental University | 2006 |
|
Aggressive Very Low-Density Lipoprotein (VLDL) and LDL Lowering by Gene Transfer of the VLDL Receptor Combined with a Low-Fat Diet Regimen Induces Regression and Reduces Macrophage Content in Advanced Atherosclerotic Lesions in LDL Receptor-Deficient Mice
ED MacDougall, F Kramer, P Polinsky, S Barnhart, B Askari, F Johansson, R Varon, ME Rosenfeld, K Oka, L Chan, SM Schwartz, KE Bornfeldt |
The American Journal of Pathology | 2006 |
|
A fibrinogen deficiency accelerates the initiation of LDL cholesterol–driven atherosclerosis via thrombin generation and platelet activation in genetically predisposed mice
T Iwaki, MJ Sandoval-Cooper, M Brechmann, VA Ploplis, FJ Castellino |
Blood | 2006 |
|
ApoE Plasma Levels and Risk of Cardiovascular Mortality in Old Age
SP Mooijaart, JF Berbée, D Heemst, LM Havekes, AJ de Craen, PE Slagboom, PC Rensen, RG Westendorp |
PLoS Medicine | 2006 |
|
Reduced Atherosclerotic Lesion Size in P-Selectin Deficient Apolipoprotein E-Knockout Mice Fed a Chow but Not a Fat Diet
MC Bourdillon, J Randon, L Barek, K Zibara, C Covacho, RN Poston, E Chignier, JL McGregor |
Journal of Biomedicine and Biotechnology | 2006 |
|
Effect of sesamin on serum cholesterol and triglycerides levels in LDL receptor-deficient mice
JL Peñalvo, A Hopia, H Adlercreutz |
European Journal of Nutrition | 2006 |
|
Effects of atorvastatin on lipid metabolism in normolipidemic and hereditary hyperlipidemic, non-laying hens
RG Elkin, Y Zhong, SS Donkin, E Hengstschläger-Ottnad, WJ Schneider |
Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology | 2006 |
|
Biomechanics of the cardiovascular system: the aorta as an illustratory example
GS Kassab |
Journal of The Royal Society Interface | 2006 |
|
Attenuation of LDL receptor gene expression by selenium deficiency during hypercholesterolemia
S Dhingra, MP Bansal |
Molecular and Cellular Biochemistry | 2006 |
|
Ursane Triterpenoids Inhibit Atherosclerosis and Xanthoma in LDL Receptor Knockout Mice
Q Zhang, Z Chang, Q Wang |
Cardiovascular Drugs and Therapy | 2006 |
|
Implication of the proprotein convertase NARC-1/PCSK9 in the development of the nervous system
S Poirier, A Prat, E Marcinkiewicz, J Paquin, BP Chitramuthu, D Baranowski, B Cadieux, HP Bennett, NG Seidah |
Journal of Neurochemistry | 2006 |
|
Hypercholesterolemia and LDL receptor mRNA expression: modulation by selenium supplementation
S Dhingra, MP Bansal |
BioMetals | 2006 |
|
Statins induce calcium-dependent mitochondrial permeability transition
JA Velho, H Okanobo, GR Degasperi, MY Matsumoto, LC Alberici, RG Cosso, HC Oliveira, AE Vercesi |
Toxicology | 2006 |
|
Adipocyte enhancer-binding protein 1 is a potential novel atherogenic factor involved in macrophage cholesterol homeostasis and inflammation
A Majdalawieh, L Zhang, IV Fuki, DJ Rader, HS Ro |
Proceedings of the National Academy of Sciences | 2006 |
|
Antiatherogenic effects of S-nitroso-N-acetylcysteine in hypercholesterolemic LDL receptor knockout mice
MH Krieger, KF Santos, SM Shishido, AC Wanschel, HF Estrela, L Santos, MG Oliveira, KG Franchini, RC Spadari-Bratfisch, FR Laurindo |
Nitric Oxide | 2006 |
|
Dietary diacylglycerol extenuates arterial thrombosis in apoE and LDLR deficient mice
Y Ijiri, A Naemura, T Yamashita, S Meguro, H Watanabe, I Tokimitsu, J Yamamoto |
Thrombosis Research | 2006 |
|
La infección de hepatocitos de rata en cultivo con adenovirus recombinantes causa un drástico descenso en la secreción de lipoproteínas de muy baja densidad
L Palacios, O Fresnedo, I García-Arcos, JV Castell, B Ochoa |
Clínica e Investigación en Arteriosclerosis | 2006 |
|
Drug-eluting stents studies in mice: Do we need atherosclerosis to study restenosis?
NM Pires, JW Jukema, MJ Daemen, PH Quax |
Vascular Pharmacology | 2006 |
|
Antiatherogenic effects of n-3 fatty acids - evidence and mechanisms
RD Caterina, A Zampolli |
Heart International | 2006 |
|
Myeloperoxidase and its contributory role in inflammatory vascular disease
D Lau, S Baldus |
Pharmacology & Therapeutics | 2006 |
|
Vascular Medicine
ES Klings, J Loscalzo |
Vascular Medicine | 2006 |
|
Abeta42 neurotoxicity in primary co-cultures: effect of apoE isoform and Abeta conformation
AM Manelli, LC Bulfinch, PM Sullivan, MJ LaDu |
Neurobiology of Aging | 2006 |
|
Aspects immunologiques de l’athérome
É Groyer, G Caligiuri, J Laschet-Khallou, A Nicoletti |
La Presse Médicale | 2006 |
|
Impact of Chromosome 2 Obesity Loci on Cardiovascular Complications of Insulin Resistance in LDL Receptor-Deficient C57BL/6 Mice
D Estrada-Smith, AR Collins, X Wang, C Crockett, L Castellani, AJ Lusis, RC Davis |
Diabetes | 2006 |
|
Innate Immune Signaling and Porphyromonas gingivalis -accelerated Atherosclerosis
FC Gibson, H Yumoto, Y Takahashi, HH Chou, CA Genco |
Journal of dental research | 2006 |
|
Increased cholesterol biosynthesis and hypercholesterolemia in mice overexpressing squalene synthase in the liver
H Okazaki, F Tazoe, S Okazaki, N Isoo, K Tsukamoto, M Sekiya, N Yahagi, Y Iizuka, K Ohashi, T Kitamine, R Tozawa, T Inaba, H Yagyu, M Okazaki, H Shimano, N Shibata, H Arai, R Nagai, T Kadowaki, J Osuga, S Ishibashi |
Journal of lipid research | 2006 |
|
Microarray analysis indicates an important role for FABP5 and putative novel FABPs on a Western-type diet
M Hoekstra, M Stitzinger, EJ van Wanrooij, IN Michon, JK Kruijt, J Kamphorst, MV Eck, E Vreugdenhil, TJ van Berkel, J Kuiper |
Journal of lipid research | 2006 |
|
Lipolytic and ligand-binding functions of hepatic lipase protect against atherosclerosis in LDL receptor-deficient mice
L Freeman, MJ Amar, R Shamburek, B Paigen, HB Brewer, S Santamarina-Fojo, H González-Navarro |
Journal of lipid research | 2006 |
|
Plant sterol or stanol esters retard lesion formation in LDL receptor-deficient mice independent of changes in serum plant sterols
J Plat, I Beugels, MJ Gijbels, MP de Winther, RP Mensink |
Journal of lipid research | 2006 |
|
Cholesterol substrate pools and steroid hormone levels are normal in the face of mutational inactivation of NPC1 protein
C Xie, JA Richardson, SD Turley, JM Dietschy |
Journal of lipid research | 2006 |
|
Transcriptional profile reveals altered hepatic lipid and cholesterol metabolism in hyposulfatemic NaS1 null mice
PA Dawson, B Gardiner, S Grimmond, D Markovich |
Physiological genomics | 2006 |
|
Binding characteristics of a panel of monoclonal antibodies against the ligand binding domain of the human LDLr
AT Nguyen, T Hirama, V Chauhan, R MacKenzie, R Milne |
Journal of lipid research | 2006 |
|
A Diet Rich in Green and Yellow Vegetables Inhibits Atherosclerosis in Mice
MR Adams, DL Golden, H Chen, TC Register, ET Gugger |
The Journal of nutrition | 2006 |
|
Antiatherogenic Effects of n-3 Fatty Acids - Evidence and Mechanisms
RD Caterina, A Zampolli |
Heart International | 2006 |
|
Mechanism of the Antithrombotic Effect of Dietary Diacylglycerol in Atherogenic Mice
Y Ijiri, A Naemura, T Yamashita, H Ikarugi, S Meguro, I Tokimitsu, J Yamamoto |
Pathophysiology of Haemostasis and Thrombosis | 2006 |
|
Simvastatin Treatment Ameliorates Autoimmune Disease Associated with Accelerated Atherosclerosis in a Murine Lupus Model
T Aprahamian, R Bonegio, J Rizzo, H Perlman, DJ Lefer, IR Rifkin, K Walsh |
Journal of immunology (Baltimore, Md. : 1950) | 2006 |
|
Attenuation of LDL receptor gene expression by selenium deficiency during hypercholesterolemia.
Dhingra S, Bansal MP |
Molecular and Cellular Biochemistry | 2006 |
|
Schoenheimer Effect explained - Feedback regulation of cholesterol synthesis in mice mediated by Insig proteins
Luke J. Engelking, Guosheng Liang, Robert E. Hammer, Kiyosumi Takaishi, Hiroshi Kuriyama, Bret M. Evers, Wei-Ping Li, Jay D. Horton, Joseph L. Goldstein, and Michael S. Brown |
Journal of Clinical Investigation | 2005 |
|
T-bet deficiency reduces atherosclerosis and alters plaque antigen-specific immune responses
C Buono, CJ Binder, G Stavrakis, JL Witztum, LH Glimcher, AH Lichtman |
Proceedings of the National Academy of Sciences | 2005 |
|
The role of circulating precursors in vascular repair and lesion formation
M Sata, D Fukuda, K Tanaka, Y Kaneda, H Yashiro, I Shirakawa |
Journal of Cellular and Molecular Medicine | 2005 |
|
Molecular evidence for arterial repair in atherosclerosis
R Karra, S Vemullapalli, C Dong, EE Herderick, X Song, K Slosek, JR Nevins, M West, PJ Goldschmidt-Clermont, D Seo |
Proceedings of the National Academy of Sciences | 2005 |
|
Quantitative Trait Locus Mapping of Genetic Modifiers of Metabolic Syndrome and Atherosclerosis in Low-Density Lipoprotein Receptor-Deficient Mice: Identification of a Locus for Metabolic Syndrome and Increased Atherosclerosis on Chromosome 4
SB Seidelmann, CD Luca, RL Leibel, JL Breslow, AR Tall, CL Welch |
Arteriosclerosis, thrombosis, and vascular biology | 2005 |
|
Decreased plasma cholesterol and hypersensitivity to statins in mice lacking Pcsk9
S Rashid, DE Curtis, R Garuti, NN Anderson, Y Bashmakov, YK Ho, RE Hammer, YA Moon, JD Horton |
Proceedings of the National Academy of Sciences | 2005 |
|
11β-HSD1 inhibition ameliorates metabolic syndrome and prevents progression of atherosclerosis in mice
A Hermanowski-Vosatka, JM Balkovec, K Cheng, HY Chen, M Hernandez, GC Koo, CB le Grand, Z Li, JM Metzger, SS Mundt, H Noonan, CN Nunes, SH Olson, B Pikounis, N Ren, N Robertson, JM Schaeffer, K Shah, MS Springer, AM Strack, M Strowski, K Wu, TJ Wu, J Xiao, BB Zhang, SD Wright, R Thieringer |
Journal of Experimental Medicine | 2005 |
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Cardioprotective effect of an endothelin receptor antagonist during ischaemia/reperfusion in the severely atherosclerotic mouse heart
AT Gonon, A Bulhak, A Bröijersén, J Pernow |
British Journal of Pharmacology | 2005 |
|
Understanding hyperlipidemia and atherosclerosis: lessons from genetically modifiedapoeandldlrmice
K Wouters, R Shiri-Sverdlov, PJ van Gorp, M Bilsen, MH Hofker |
Clinical Chemistry and Laboratory Medicine | 2005 |
|
Gene therapy for lipoprotein disorders
UC Broedl, DJ Rader |
Expert Opinion on Biological Therapy | 2005 |
|
Genes and atherosclerosis: at the origin of the predisposition
P Puddu, E Cravero, GM Puddu, A Muscari |
International Journal of Clinical Practice | 2005 |
|
Diet-dependent cardiovascular lipid metabolism controlled by hepatic LXRα
M Lehrke, C Lebherz, SC Millington, HP Guan, J Millar, DJ Rader, JM Wilson, MA Lazar |
Cell Metabolism | 2005 |
|
Effect of Adenovirus-Mediated Transfer of the CTLA4IG Gene in Hamster-to-Rat Xenotransplantation
S Hayashi, D Leu, Y Yamii, G Mei, H Takagi, A Nakao |
Transplantation | 2005 |
|
Creatine Kinase, a Magnetic Resonance-Detectable Marker Gene for Quantification of Liver-Directed Gene Transfer
Z Li, H Qiao, C Lebherz, SR Choi, X Zhou, G Gao, HF Kung, DJ Rader, JM Wilson, JD Glickson, R Zhou |
Human Gene Therapy | 2005 |
|
Atherosclerosis quantitative trait loci are sex- and lineage-dependent in an intercross of C57BL/6 and FVB/N low-density lipoprotein receptor-/- mice
D Teupser, M Tan, AD Persky, JL Breslow |
Proceedings of the National Academy of Sciences | 2005 |
|
Inhibition and regression of atherosclerotic lesions
K Oka, L Chan |
Acta biochimica Polonica | 2005 |
|
Absence of 12/15 lipoxygenase reduces brain oxidative stress in apolipoprotein E-deficient mice
CM Chinnici, Y Yao, T Ding, CD Funk, D Praticò |
The American Journal of Pathology | 2005 |
|
Varying the ratio of dietary n−6/n−3 polyunsaturated fatty acid alters the tendency to thrombosis and progress of atherosclerosis in apoE−/− LDLR−/− double knockout mouse
T Yamashita, E Oda, T Sano, T Yamashita, Y Ijiru, JC Giddings, J Yamamoto |
Thrombosis Research | 2005 |
|
Antioxidant effects and the therapeutic mode of action of calcium channel blockers in hypertension and atherosclerosis
T Godfraind |
Philosophical Transactions of the Royal Society B: Biological Sciences | 2005 |
|
International Review of Neurobiology
ZT Bloomgarden |
International review of neurobiology | 2005 |
|
Long term Rho-kinase inhibition ameliorates endothelial dysfunction in LDL-Receptor deficient mice
K Steioff, H Rütten, AE Busch, O Plettenburg, Y Ivashchenko, M Löhn |
European Journal of Pharmacology | 2005 |
|
Endothelial lipase modulates HDL but has no effect on atherosclerosis development in apoE −/− and LDLR −/− mice
KW Ko, A Paul, K Ma, L Li, L Chan |
Journal of lipid research | 2005 |
|
Triglyceride-rich lipoprotein metabolism in unique VLDL receptor, LDL receptor, and LRP triple-deficient mice
SM Santo, PC Rensen, JR Goudriaan, A Bensadoun, N Bovenschen, PJ Voshol, LM Havekes, BJ van Vlijmen |
Journal of lipid research | 2005 |
|
Delineation of molecular changes in intrahepatic cholesterol metabolism resulting from diminished cholesterol absorption
JJ Repa, SD Turley, G Quan, JM Dietschy |
Journal of lipid research | 2005 |
|
Quantitative Trait Locus Analysis of Atherosclerosis in an Intercross Between C57BL/6 and C3H Mice Carrying the Mutant Apolipoprotein E Gene
Z Su, Y Li, JC James, M McDuffie, AH Matsumoto, GA Helm, JL Weber, AJ Lusis, W Shi |
Genetics | 2005 |
|
Differential effects of exercise on aortic mitochondria
CG Young, CA Knight, KC Vickers, D Westbrook, NR Madamanchi, MS Runge, H Ischiropoulos, SW Ballinger |
American journal of physiology. Heart and circulatory physiology | 2005 |
|
Liver disease with altered bile acid transport in Niemann-Pick C mice on a high-fat, 1% cholesterol diet
RP Erickson, A Bhattacharyya, RJ Hunter, RA Heidenreich, NJ Cherrington |
AJP Gastrointestinal and Liver Physiology | 2005 |
|
Effect of conjugated linoleic acid isomers on lipoproteins and atherosclerosis in the Syrian Golden hamster
PL Mitchell, MA Langille, DL Currie, RS McLeod |
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids | 2005 |
|
Principles of Molecular Cardiology
MS Runge, C Patterson |
2005 | |
|
LDL receptor cooperates with LDL receptor–related protein in regulating plasma levels of coagulation factor VIII in vivo
N Bovenschen, K Mertens, L Hu, LM Havekes, BJ van Vlijmen |
Blood | 2005 |
|
DNA Repair and Mutagenesis
EC Friedberg, GC Walker, W Siede, RD Wood, RA Schultz, T Ellenberger |
2005 | |
|
The Minor Receptor Group of Human Rhinovirus (HRV) Includes HRV23 and HRV25, but the Presence of a Lysine in the VP1 HI Loop Is Not Sufficient for Receptor Binding
M Vlasak, M Roivainen, M Reithmayer, I Goesler, P Laine, L Snyers, T Hovi, D Blaas |
Journal of virology | 2005 |
|
Lipid peroxidation and oxidant stress regulate hepatic apolipoprotein B degradation and VLDL production
Meihui Pan, Arthur I. Cederbaum, Yuan-Li Zhang, Henry N. Ginsberg, Kevin Jon Williams, and Edward A. Fisher |
Journal of Clinical Investigation | 2004 |
|
Roles of thromboxane A2 and prostacyclin in development of atherosclerosis in apoE-deficient mice
Takuya Kobayashi, Yoshio Tahara, Mayumi Matsumoto, Masako Iguchi, Hideto Sano, Toshinori Murayama, Hidenori Arai, Hiroji Oida, Takami Yurugi-Kobayashi, Jun Yamashita, Hiroyuki Katagiri, Masataka Majima, Masayuki Yokode, Toru Kita, and Shuh Narumiya |
Journal of Clinical Investigation | 2004 |
|
Impaired clearance of apoptotic cells promotes synergy between atherogenesis and autoimmune disease
T Aprahamian, I Rifkin, R Bonegio, B Hugel, JM Freyssinet, K Sato, JJ Castellot, K Walsh |
Journal of Experimental Medicine | 2004 |
|
Osteoclast formation, survival and morphology are highly dependent on exogenous cholesterol/lipoproteins
E Luegmayr, H Glantschnig, GA Wesolowski, MA Gentile, JE Fisher, GA Rodan, AA Reszka |
Cell Death and Differentiation | 2004 |
|
Cellular and Molecular Mechanisms of Atherosclerosis with Mouse Models
R Ohashi, H Mu, Q Yao, C Chen |
Trends in Cardiovascular Medicine | 2004 |
|
Blasts from the past
PA Insel, S Kornfeld, PW Majerus, AR Marks, PA Marks, AS Relman, BF Scharschmidt, TP Stossel, AP Varki, SJ Weiss, JD Wilson |
Journal of Clinical Investigation | 2004 |
|
Reflecting on 80 years of excellence
U Savla |
Journal of Clinical Investigation | 2004 |
|
Les processus digestifs et absorptifs des lipides alimentaires
V Marcil, N Peretti, E Delvin, E Levy |
Gastroentérologie Clinique et Biologique | 2004 |
|
Immunomodulation and vaccination for atherosclerosis
X Zhou, GK Hansson |
Expert Opinion on Biological Therapy | 2004 |
|
Low-density lipoprotein receptor-knockout mice display impaired spatial memory associated with a decreased synaptic density in the hippocampus
M Mulder, PJ Jansen, BJ Janssen, WD van de Berg, H der Boom, LM Havekes, RE de Kloet, FC Ramaekers, A Blokland |
Neurobiology of Disease | 2004 |
|
Distribution of the lipolysis stimulated receptor in adult and embryonic murine tissues and lethality of LSR-/- embryos at 12.5 to 14.5 days of gestation
S Mesli, S Javorschi, AM Bérard, M Landry, H Priddle, D Kivlichan, AJ Smith, FT Yen, BE Bihain, M Darmon |
European Journal of Biochemistry | 2004 |
|
Heterogeneous expression of apolipoprotein-E by human macrophages
N Tedla, EN Glaros, UT Brunk, W Jessup, B Garner |
Immunology | 2004 |
|
Adenovirus-mediated overexpression of tissue inhibitor of metalloproteinases-1 in the liver: efficient protection against T-cell lymphoma and colon carcinoma metastasis
S Elezkurtaj, C Kopitz, AH Baker, A Perez-Cant�, MJ Arlt, R Khokha, B Gansbacher, M Anton, K Brand, A Kr�ger |
The Journal of Gene Medicine | 2004 |
|
Chronic treatment with bark infusion fromCroton cajucaralowers plasma triglyceride levels in genetic hyperlipidemic mice
EJ Bighetti, AR Souza-Brito, EC de Faria, HC Oliveira |
Canadian Journal of Physiology and Pharmacology | 2004 |
|
Antigen-tailored therapy based on the inflammatory theory of atherosclerosis
D Harats, J George |
Expert Review of Vaccines | 2004 |
|
Effects of streptozotocin-induced diabetes in apolipoprotein AI deficient mice
IJ Goldberg, A Isaacs, E Sehayek, JL Breslow, LS Huang |
Atherosclerosis | 2004 |
|
Phenytoin treatment reduces atherosclerosis in mice through mechanisms independent of plasma HDL-cholesterol concentration
C Trocho, JC Escolà-Gil, V Ribas, S Benı́tez, JM Martı́n-Campos, N Rotllan, L Osaba, J Ordóñez-Llanos, F González-Sastre, F Blanco-Vaca |
Atherosclerosis | 2004 |
|
Overexpression of 15-Lipoxygenase in the Vascular Endothelium Is Associated with Increased Thymic Apoptosis in LDL Receptor-Deficient Mice
A Afek, N Zurgil, Y Bar-Dayan, S Polak-Charcon, I Goldberg, M Deutsch, J Kopolovich, G Keren, D Harats, J George |
Pathobiology | 2004 |
|
Physical Activity and Atherosclerosis: Which Animal Model?
JR Turk, MH Laughlin |
Canadian Journal of Applied Physiology | 2004 |
|
Technical Assessment of the First 20 Years of Research Using Mouse Embryonic Stem Cell Lines
GJ Downing, JF Battey |
Stem Cells | 2004 |
|
Identification of the human rhinovirus serotype 1A binding site on the murine low-density lipoprotein receptor by using human-mouse receptor chimeras
B Herdy, L Snyers, M Reithmayer, P Hinterdorfer, D Blaas |
Journal of virology | 2004 |
|
Adenoviral-mediated expression of Pcsk9 in mice results in a low-density lipoprotein receptor knockout phenotype
KN Maxwell, JL Breslow |
Proceedings of the National Academy of Sciences | 2004 |
|
Annexin 2-caveolin 1 complex is a target of ezetimibe and regulates intestinal cholesterol transport
EJ Smart, RA de Rose, SA Farber |
Proceedings of the National Academy of Sciences | 2004 |
|
A practical approach to using mice in atherosclerosis research
SC Whitman |
The Clinical biochemist. Reviews / Australian Association of Clinical Biochemists | 2004 |
|
Dual role for scavenger receptor class B, type I on bone marrow-derived cells in atherosclerotic lesion development
MV Eck, IS Bos, RB Hildebrand, BT van Rij, TJ van Berkel |
The American Journal of Pathology | 2004 |
|
Naringin alters the cholesterol biosynthesis and antioxidant enzyme activities in LDL receptor-knockout mice under cholesterol fed condition
HJ Kim, GT Oh, YB Park, MK Lee, HJ Seo, MS Choi |
Life Sciences | 2004 |
|
Mr and fluorescent imaging of low-density lipoprotein receptors1
H Li, BD Gray, I Corbin, C Lebherz, H Choi, S Lund-Katz, JM Wilson, JD Glickson, R Zhou |
Academic Radiology | 2004 |
|
Distribution of the lipolysis stimulated receptor in adult and embryonic murine tissues and lethality of LSR-/- embryos at 12.5 to 14.5 days of gestation: LSR gene and protein expression
S Mesli, S Javorschi, AM Bérard, M Landry, H Priddle, D Kivlichan, AJ Smith, FT Yen, BE Bihain, M Darmon |
European Journal of Biochemistry | 2004 |
|
Post-transcriptional Regulation of Low Density Lipoprotein Receptor Protein by Proprotein Convertase Subtilisin/Kexin Type 9a in Mouse Liver
SW Park, YA Moon, JD Horton |
The Journal of biological chemistry | 2004 |
|
Binding of Low Density Lipoprotein to Platelet Apolipoprotein E Receptor 2′ Results in Phosphorylation of p38 MAPK
SJ Korporaal, IA Relou, M Eck, V Strasser, M Bezemer, G Gorter, TJ van Berkel, J Nimpf, JW Akkerman, PJ Lenting |
The Journal of biological chemistry | 2004 |
|
High-level expression of ABCG5 and ABCG8 attenuates diet-induced hypercholesterolemia and atherosclerosis in Ldlr−/− mice
KR Wilund, L Yu, F Xu, HH Hobbs, JC Cohen |
Journal of lipid research | 2004 |
|
Macrophage-specific overexpression of group IIa sPLA 2 increases atherosclerosis and enhances collagen deposition
SA Ghesquiere, MJ Gijbels, M Anthonsen, PJ van Gorp, I der Made, B Johansen, MH Hofker, MP de Winther |
Journal of lipid research | 2004 |
|
Low-density lipoprotein receptor gene therapy using helper-dependent adenovirus produces long-term protection against atherosclerosis in a mouse model of familial hypercholesterolemia
S Nomura, A Merched, E Nour, C Dieker, K Oka, L Chan |
Gene Therapy | 2004 |
|
Defective VLDL metabolism and severe atherosclerosis in mice expressing human apolipoprotein E isoforms but lacking the LDL receptor
C Knouff, O Briand, S Lestavel, V Clavey, M Altenburg, N Maeda |
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids | 2004 |
|
A sensitive noninvasive method for monitoring successful liver-directed gene transfer of the low-density lipoprotein receptor in Watanabe hyperlipidemic rabbits in vivo
UJ Tietge, G Cichon, C Büttner, J Genschel, J Heeren, P Gielow, N Grewe, M Dogar, U Beisiegel, MP Manns, H Lochs, W Burchert, HH Schmidt |
Gene Therapy | 2004 |
|
Sterol regulation of scavenger receptor class B type I in macrophages
L Yu, G Cao, J Repa, H Stangl |
Journal of lipid research | 2004 |
|
The Role of α 1 -Fetoprotein Transcription Factor/LRH-1 in Bile Acid Biosynthesis: A KNOWN NUCLEAR RECEPTOR ACTIVATOR THAT CAN ACT AS A SUPPRESSOR OF BILE ACID BIOSYNTHESIS
A Castillo-Olivares, JA Campos, WM Pandak, G Gil |
The Journal of biological chemistry | 2004 |
|
Increased Sensitivity to Dietary Cholesterol in Diabetic and Hypothyroid Rats Associated with Low Levels of Hepatic HMG-CoA Reductase Expression
GC Ness, KR Gertz |
Experimental biology and medicine (Maywood, N.J.) | 2004 |
|
Scavenger Receptor BI Plays a Role in Facilitating Chylomicron Metabolism
R Out, JK Kruijt, PC Rensen, RB Hildebrand, P Vos, MV Eck, TJ van Berkel |
The Journal of biological chemistry | 2004 |
|
Dietary Soy β-Conglycinin (7S Globulin) Inhibits Atherosclerosis in Mice
MR Adams, DL Golden, AA Franke, SM Potter, HS Smith, MS Anthony |
The Journal of nutrition | 2004 |
|
Oxidative stress in atherosclerosis‐prone mouse is due to low antioxidant capacity of mitochondria
CF Oliveira, GR Cosso, CL Alberici, NE Maciel, GA Salerno, GG Dorighello, AJ Velho, EC Faria, AE Vercesi |
The FASEB Journal | 2004 |
|
The Physiological Genomics of the Critically Ill Mouse
C Ince |
2004 | |
|
Transgenic Models in Pharmacology
S Offermanns, L Hein |
2004 | |
|
Deficiency of Cathepsin S Reduces Atherosclerosis In Low-Density Lipoprotein Receptor-Deficient Mice
Galina K. Sukhova, Yaou Zhang, Jie-Hong Pan, Youichiro Wada, Takashi Yamamoto, Makoto Naito, Tatsuhiko Kodama, Sotirios Tsimikas, Joseph L. Witztum, Michael L. Lu, Yasuhiko Sakara, Michael T. Chin, Peter Libby, Guo-Ping Shi |
Journal of Clinical Investigation | 2003 |
|
Inhibition of NF-kappaB activation in macrophages promotes atherosclerosis in low-density lipoprotein receptor deficient mice
Edwin Kanters, Manolis Pasparakis, Marion J.J. Gijbels, Monique N. Vergouwe, Iris Partouns-Hendriks, Remond J.A. Fijneman, Björn E. Clausen, Irmgard Förster, Mark M. Kockx, Klaus Rajewsky, Georg Kraal, Marten H. Hofker, Menno P.J. de Winther |
Journal of Clinical Investigation | 2003 |
|
The atherogenic effect of excess methionine intake
AM Troen, E Lutgens, DE Smith, IH Rosenberg, J Selhub |
Proceedings of the National Academy of Sciences | 2003 |
|
Hematopoietic NF- B1 deficiency results in small atherosclerotic lesions with an inflammatory phenotype
E Kanters |
Blood | 2003 |
|
Deficiency of acyl CoA:cholesterol acyltransferase 2 prevents atherosclerosis in apolipoprotein E-deficient mice
EL Willner, B Tow, KK Buhman, M Wilson, DA Sanan, LL Rudel, RV Farese |
Proceedings of the National Academy of Sciences | 2003 |
|
A20, a regulator of NFkappaB, maps to an atherosclerosis locus and differs between parental sensitive C57BL/6J and resistant FVB/N strains
S Idel, HM Dansky, JL Breslow |
Proceedings of the National Academy of Sciences | 2003 |
|
Two Hsp70 family members expressed in atherosclerotic lesions
Z Han, QA Truong, S Park, JL Breslow |
Proceedings of the National Academy of Sciences | 2003 |
|
Superoxide dismutase mimetic M40403 improves endothelial function in apolipoprotein(E)-deficient mice
F Jiang, Y Guo, D Salvemini, GJ Dusting |
British Journal of Pharmacology | 2003 |
|
The Role of the High-Density Lipoprotein Receptor SR-BI in the Lipid Metabolism of Endocrine and Other Tissues
A Rigotti, HE Miettinen, M Krieger |
Endocrine reviews | 2003 |
|
LRP: Role in Vascular Wall Integrity and Protection from Atherosclerosis
P Boucher, M Gotthardt, WP Li, RG Anderson, J Herz |
Science | 2003 |
|
Dyslipidaemia
P Durrington |
The Lancet | 2003 |
|
Sepsis syndrome stimulates proximal tubule cholesterol synthesis and suppresses the SR-B1 cholesterol transporter
RA Zager, AC Johnson, SY Hanson |
Kidney International | 2003 |
|
Mouse models as tools for dissecting disorders of lipoprotein metabolism
P Marschang, J Herz |
Seminars in Cell & Developmental Biology | 2003 |
|
The Role of Interleukin-4 and Interleukin-12 in the Progression of Atherosclerosis in Apolipoprotein E-Deficient Mice
P Davenport, PG Tipping |
The American Journal of Pathology | 2003 |
|
Activin and TR3 orphan receptor: Two 'atheroprotective' genes as evidenced in dedicated mouse models
MA Engelse, EK Arkenbout, H Pannekoek, CJ de Vries |
Clinical and Experimental Pharmacology and Physiology | 2003 |
|
Induction of Fatal Inflammation in LDL Receptor and ApoA-I Double-Knockout Mice Fed Dietary Fat and Cholesterol
M Zabalawi, S Bhat, T Loughlin, MJ Thomas, E Alexander, M Cline, B Bullock, M Willingham, MG Sorci-Thomas |
The American Journal of Pathology | 2003 |
|
Apolipoprotein E modulates immune activation by acting on the antigen-presenting cell
C Tenger, X Zhou |
Immunology | 2003 |
|
Human rhinovirus type 2 is internalized by clathrin-mediated endocytosis
L Snyers, H Zwickl, D Blaas |
Journal of virology | 2003 |
|
Nonneurotropic adenovirus: a vector for gene transfer to the brain and gene therapy of neurological disorders
PR Lowenstein, D Suwelack, J Hu, X Yuan, M Jimenez-Dalmaroni, S Goverdhana, MG Castro |
International review of neurobiology | 2003 |
|
Lipid-lowering effects of TAK-475, a squalene synthase inhibitor, in animal models of familial hypercholesterolemia
Y Amano, T Nishimoto, R Tozawa, E Ishikawa, Y Imura, Y Sugiyama |
European Journal of Pharmacology | 2003 |
|
Lipoprotein subclass profiles of hyperlipidemic diabetic mice measured by nuclear magnetic resonance spectroscopy
SM Hammad, L Powell-Braxton, JD Otvos, L Eldridge, W Won, TJ Lyons |
Metabolism | 2003 |
|
Impact of an enriched-cholesterol diet on enzymatic cholesterol metabolism during rabbit gestation
A Montoudis, S Boileau, L Simoneau, J Lafond |
Life Sciences | 2003 |
|
Elevation of ceramide in serum lipoproteins during acute phase response in humans and mice: role of serine–palmitoyl transferase
S Lightle, R Tosheva, A Lee, J Queen-Baker, B Boyanovsky, S Shedlofsky, M Nikolova-Karakashian |
Archives of Biochemistry and Biophysics | 2003 |
|
Familial hypercholesterolemia—Improving treatment and meeting guidelines
PN Hopkins |
International Journal of Cardiology | 2003 |
|
Gene Therapy for Cardiovascular Disease
KL Dishart, LM Work, L Denby, AH Baker |
Journal of Biomedicine and Biotechnology | 2003 |
|
The Low Density Lipoprotein Receptor Prevents Secretion of Dense ApoB100-containing Lipoproteins from the Liver
SL Larsson, J Skogsberg, J Björkegren |
The Journal of biological chemistry | 2003 |
|
The Low Density Lipoprotein Receptor-related Protein Complexes with Cell Surface Heparan Sulfate Proteoglycans to Regulate Proteoglycan-mediated Lipoprotein Catabolism
LC Wilsie, RA Orlando |
The Journal of biological chemistry | 2003 |
|
Quantitative trait loci that determine lipoprotein cholesterol levels in DBA/2J and CAST/Ei inbred mice ,
MA Lyons, H Wittenburg, R Li, KA Walsh, GA Churchill, MC Carey, B Paigen |
Journal of lipid research | 2003 |
|
Invited Review: Identifying new mouse models of cardiovascular disease: a review of high-throughput screens of mutagenized and inbred strains
KL Svenson, MA Bogue, LL Peters |
Journal of applied physiology | 2003 |
|
Activating Signal Cointegrator 2 Required for Liver Lipid Metabolism Mediated by Liver X Receptors in Mice
SW Kim, K Park, E Kwak, E Choi, S Lee, J Ham, H Kang, JM Kim, SY Hwang, YY Kong, K Lee, JW Lee |
Molecular and cellular biology | 2003 |
|
Intravenous gene therapy for familial hypercholesterolemia using ligand-facilitated transfer of a liposome:LDL receptor gene complex
M Shichiri, A Tanaka, Y Hirata |
Gene Therapy | 2003 |
|
Infectious delivery of a 135-kb LDLR genomic locus leads to regulated complementation of low-density lipoprotein receptor deficiency in human cells
R Wade-Martins, Y Saeki, EA Chiocca |
Molecular Therapy | 2003 |
|
Overexpression of Sterol Regulatory Element-binding Protein-1a in Mouse Adipose Tissue Produces Adipocyte Hypertrophy, Increased Fatty Acid Secretion, and Fatty Liver
JD Horton, I Shimomura, S Ikemoto, Y Bashmakov, RE Hammer |
The Journal of biological chemistry | 2003 |
|
Dietary sodium chloride restriction enhances aortic wall lipid storage and raises plasma lipid concentration in LDL receptor knockout mice
S Catanozi, JC Rocha, M Passarelli, ML Guzzo, C Alves, LN Furukawa, VS Nunes, ER Nakandakare, JC Heimann, EC Quintão |
Journal of lipid research | 2003 |
|
Eliminating Atherogenesis in Mice by Switching Off Hepatic Lipoprotein Secretion
HD Lieu, SK Withycombe, Q Walker, JX Rong, RL Walzem, JS Wong, RL Hamilton, EA Fisher, SG Young |
Circulation | 2003 |
|
Atherosclerosis, Hypertension and Diabetes
GN Pierce, M Nagano, P Zahradka, NS Dhalla |
2003 | |
|
Atlas of Atherosclerosis
PW Wilson |
2003 | |
|
Oral tolerance with heat shock protein 65 attenuates mycobacterium tuberculosis-inducedand high-fat-diet-driven atherosclerotic lesions
D Harats, N Yacov, B Gilburd, Y Shoenfeld, J George |
Journal of the American College of Cardiology | 2002 |
|
LDL receptor-GFP fusion proteins: new tools for the characterisation of disease-causing mutations in the LDL receptor gene
HU Holst, F Dagnaes-Hansen, TJ Corydon, PH Andreasen, MM Jørgensen, S Kølvraa, L Bolund, TG Jensen |
European Journal of Human Genetics | 2002 |
|
Prolonged stimulation of the adrenals by corticotropin suppresses hepatic low-density lipoprotein and high-density lipoprotein receptors and increases plasma cholesterol
C Gälman, B Angelin, M Rudling |
Endocrinology | 2002 |
|
Maternal loading with very low-density lipoproteins stimulates fetal surfactant synthesis
AJ Ryan, JD Medh, DM McCoy, RG Salome, RK Mallampalli |
American journal of physiology. Lung cellular and molecular physiology | 2002 |
|
The potential for novel anti-inflammatory therapies for coronary artery disease
MA Cascieri |
Nature Reviews Drug Discovery | 2002 |
|
Laser capture microdissection analysis of gene expression in macrophages from atherosclerotic lesions of apolipoprotein E-deficient mice
E Trogan, RP Choudhury, HM Dansky, JX Rong, JL Breslow, EA Fisher |
Proceedings of the National Academy of Sciences | 2002 |
|
Experimental control of pancreatic development and maintenance
AM Holland, MA Hale, H Kagami, RE Hammer, RJ MacDonald |
Proceedings of the National Academy of Sciences | 2002 |
|
Disruption of Abcg5 and Abcg8 in mice reveals their crucial role in biliary cholesterol secretion
L Yu, RE Hammer, J Li-Hawkins, KV Bergmann, D Lutjohann, JC Cohen, HH Hobbs |
Proceedings of the National Academy of Sciences | 2002 |
|
Normal production rate of apolipoprotein B in LDL receptor-deficient mice
H Shimano, I Shimomura, RE Hammer, J Herz, JL Goldstein, MS Brown, JD Horton |
Journal of Clinical Investigation | 2002 |
|
Encyclopedia of Molecular Biology
B Mannervik |
Encyclopedia of Molecular Biology | 2002 |
|
Recent advances in liver-directed gene therapy for dyslipidemia
K Oka, L Chan |
Current Atherosclerosis Reports | 2002 |
|
Mouse Models of Atherosclerosis
A Daugherty |
The American Journal of the Medical Sciences | 2002 |
|
LIPOPROTEINRECEPTORS IN THENERVOUSSYSTEM
J Herz, HH Bock |
Annual Review of Biochemistry | 2002 |
|
Adenovirus and Adeno-Associated Virus Vectors
CM Lai, YK Lai, PE Rakoczy |
DNA and Cell Biology | 2002 |
|
Combined effects of cholesterol reduction and apolipoprotein A-I expression on atherosclerosis in LDL receptor deficient mice
M Kawashiri, YZ Zhang, E Puré, DJ Rader |
Atherosclerosis | 2002 |
|
VLDL receptor deficiency enhances intimal thickening after vascular injury but does not affect atherosclerotic lesion area
PJ Tacken, DJ Delsing, MJ Gijbels, PH Quax, LM Havekes, MH Hofker, KW van Dijk |
Atherosclerosis | 2002 |
|
A new model to evaluate the diet-induced prothrombotic state, using He–Ne laser-induced thrombogenesis in the carotid artery of apolipoprotein E-deficient and low-density lipoprotein receptor-deficient mice
Y Ijiri, M Miura, M Hashimoto, C Fukunaga, S Watanabe, A Kubota, K Oiwa, T Okuda, J Yamamoto |
Blood Coagulation & Fibrinolysis | 2002 |
|
MCMV infection increases early T-lymphocyte influx in atherosclerotic lesions in apoE knockout mice
I Vliegen, F Stassen, G Grauls, R Blok, C Bruggeman |
Journal of Clinical Virology | 2002 |
|
Transgenic systems in drug discovery: from target identification to humanized mice
J Törnell, M Snaith |
Drug Discovery Today | 2002 |
|
A Rapid PCR Method of Genotyping LDL Receptor Mutations in WHHL Rabbits
H Sun, S Usui, M Shiomi, T Watanabe, J Fan |
Journal of Atherosclerosis and Thrombosis | 2002 |
|
Leukocyte ABCA1 controls susceptibility to atherosclerosis and macrophage recruitment into tissues
M Eck, IS Bos, WE Kaminski, E Orsó, G Rothe, J Twisk, A Böttcher, ES van Amersfoort, TA Christiansen-Weber, WP Fung-Leung, TJ van Berkel, G Schmitz |
Proceedings of the National Academy of Sciences | 2002 |
|
A bovine papillomavirus-1 based vector restores the function of the low-density lipoprotein receptor in the receptor-deficient CHO-ldlA7 cell line
J Tammur, H Sibul, E Ustav, M Ustav, A Metspalu |
BMC Molecular Biology | 2002 |
|
Endoplasmic reticulum localization of the low density lipoprotein receptor mediates presecretory degradation of apolipoprotein B
DL Gillian-Daniel, PW Bates, A Tebon, AD Attie |
Proceedings of the National Academy of Sciences | 2002 |
|
A phenotype-sensitizing Apoe-deficient genetic background reveals novel atherosclerosis predisposition loci in the mouse
HM Dansky, P Shu, M Donavan, J Montagno, DL Nagle, JS Smutko, N Roy, S Whiteing, J Barrios, TJ McBride, JD Smith, G Duyk, JL Breslow, KJ Moore |
Genetics | 2002 |
|
Insulin suppression of VLDL apo B secretion is not mediated by the LDL receptor
DV Chirieac, J Cianci, HL Collins, JD Sparks, CE Sparks |
Biochemical and Biophysical Research Communications | 2002 |
|
Platelet-activating factor receptor
S Ishii, T Nagase, T Shimizu |
Prostaglandins & Other Lipid Mediators | 2002 |
|
L IPOPROTEIN R ECEPTORS IN THE N ERVOUS S YSTEM
J Herz, HH Bock |
Annual Review of Biochemistry | 2002 |
|
Shifting the LDL-receptor paradigm in familial hypercholesterolemia: novel insights from recent kinetic studies of apolipoprotein B-100 metabolism
PH Barrett, GF Watts |
Atherosclerosis Supplements | 2002 |
|
Normal production rate of apolipoprotein B in LDL receptor-deficient mice
H Shimano, I Shimomura, RE Hammer, J Herz, JL Goldstein, MS Brown, JD Horton |
Arteriosclerosis, thrombosis, and vascular biology | 2002 |
|
HOE 402 lowers serum cholesterol levels by reducing VLDL-lipid production, and not by induction of the LDL receptor, and reduces atherosclerosis in wild-type and LDL receptor-deficient mice
R Draijer, OL Volger, VE Dahlmans, EC de Wit, LM Havekes, HM Princen |
Biochemical Pharmacology | 2002 |
|
Influence of C3 deficiency on atherosclerosis
C Buono, CE Come, JL Witztum, GF Maguire, PW Connelly, M Carroll, AH Lichtman |
Circulation | 2002 |
|
The inhibitory effect of soy protein isolate on atherosclerosis in mice does not require the presence of LDL receptors or alteration of plasma lipoproteins
MR Adams, DL Golden, MS Anthony, TC Register, JK Williams |
The Journal of nutrition | 2002 |
|
Effect of a long-chained fructan Raftiline HP on blood lipids and spontaneous atherosclerosis in low density receptor knockout mice
A Mortensen, M Poulsen, H Frandsen |
Nutrition Research | 2002 |
|
Estradiol suppresses vascular monocyte chemotactic protein-1 expression during early atherogenesis
E Seli, UA Kayisli, B Selam, M Seli, A Arici |
American Journal of Obstetrics and Gynecology | 2002 |
|
Adipocyte Fatty Acid–Binding Protein, aP2, Alters Late Atherosclerotic Lesion Formation in Severe Hypercholesterolemia
JB Boord, K Maeda, L Makowski, VR Babaev, S Fazio, MR Linton, GS Hotamisligil |
Arteriosclerosis, thrombosis, and vascular biology | 2002 |
|
Molecular approaches for the treatment of atherosclerosis
Michael J Mann, Victor J Dzau |
Cardiology Clinics | 2002 |
|
Cytotoxic Immune Response Blunts Long-Term Transgene Expression after Efficient Retroviral-Mediated Hepatic Gene Transfer in Rat
D Aubert, S Ménoret, E Chiari, V Pichard, S Durand, L Tesson, P Moullier, I Anegon, N Ferry |
Molecular Therapy | 2002 |
|
Dexamethasone stimulates very low density lipoprotein (VLDL) receptor gene expression in differentiating 3T3-L1 cells
K Ensler, M Mohammadieh, A Bröijersén, B Angelin, M Gåfvels |
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids | 2002 |
|
Fatty acids differentially regulate hepatic cholesteryl ester formation and incorporation into lipoproteins in the liver of the mouse
C Xie, LA Woollett, SD Turley, JM Dietschy |
Journal of lipid research | 2002 |
|
Severe Hypercholesterolemia, Impaired Fat Tolerance, and Advanced Atherosclerosis in Mice Lacking Both Low Density Lipoprotein Receptor-related Protein 5 and Apolipoprotein E
K Magoori, MJ Kang, MR Ito, H Kakuuchi, RX Ioka, A Kamataki, DH Kim, H Asaba, S Iwasaki, YA Takei, M Sasaki, S Usui, M Okazaki, S Takahashi, M Ono, M Nose, J Sakai, T Fujino, TT Yamamoto |
The Journal of biological chemistry | 2002 |
|
Expression Cloning and Characterization of a Novel Glycosylphosphatidylinositol-anchored High Density Lipoprotein-binding Protein, GPI-HBP1
RX Ioka, MJ Kang, S Kamiyama, DH Kim, K Magoori, A Kamataki, Y Ito, YA Takei, M Sasaki, T Suzuki, H Sasano, S Takahashi, J Sakai, T Fujino, TT Yamamoto |
The Journal of biological chemistry | 2002 |
|
Repeated Three-Dimensional Magnetic Resonance Imaging of Atherosclerosis Development in Innominate Arteries of Low-Density Lipoprotein Receptor-Knockout Mice
PD Hockings, T Roberts, GJ Galloway, DG Reid, DA Harris, M Vidgeon-Hart, PH Groot, KE Suckling, GM Benson |
Circulation | 2002 |
|
Altered Pattern of Vascular Connexin Expression in Atherosclerotic Plaques
BR Kwak, F Mulhaupt, N Veillard, DB Gros, F Mach |
Arteriosclerosis, thrombosis, and vascular biology | 2002 |
|
Species-Specific Receptor Recognition by a Minor-Group Human Rhinovirus (HRV): HRV Serotype 1A Distinguishes between the Murine and the Human Low-Density Lipoprotein Receptor
M Reithmayer, A Reischl, L Snyers, D Blaas |
Journal of virology | 2002 |
|
Molecular Biology of Picornavirus
BL Semler, E Wimmer |
2002 | |
|
Upregulation of hepatic LDL transport by n-3 fatty acids in LDL receptor knockout mice
C Vasandani, AI Kafrouni, A Caronna, Y Bashmakov, M Gotthardt, JD Horton, DK Spady |
Journal of lipid research | 2002 |
|
Altered activities of anti-atherogenic enzymes LCAT, paraoxonase, and platelet-activating factor acetylhydrolase in atherosclerosis-susceptible mice
TM Forte, G Subbanagounder, JA Berliner, PJ Blanche, AO Clermont, Z Jia, MN Oda, RM Krauss, JK Bielicki |
Journal of lipid research | 2002 |
|
Interleukin-4 deficiency promotes gallstone formation
VL King, SJ Szilvassy, A Daugherty |
Journal of lipid research | 2002 |
|
Increased atherosclerosis in LDL receptor-null mice lacking ACAT1 in macrophages
Segio Fazio, Amy S. Major, Larry L. Swift, Linda A. Gleaves, Michel Accad, MacRae F. Linton, Robert V. Farese, Jr. |
Journal of Clinical Investigation | 2001 |
|
A major role for VCAM-1, but not ICAM-1, in early atherosclerosis
Myron I. Cybulsky, Kaeko Iiyama, Hongmei Li, Suning Zhu, Mian Chen, Motoi Iiyama, Vannessa Davis, Jose-Carlos Gutierrez-Ramos, Philip W. Connelly, David S. Milstone |
Journal of Clinical Investigation | 2001 |
|
Targeted deletion of CX3CR1 reveals a role for fractalkine in cardiac allograft rejection
Christopher A. Haskell, Wayne W. Hancock, David J. Salant, Wei Gao, Vilmos Csizmadia, Wendy Peters, Kerrie Faia, Omar Fituri, James B. Rottman, Israel F. Charo |
Journal of Clinical Investigation | 2001 |
|
Abnormal lipoprotein metabolism in HDL receptor (SR-BI)-deficient mice and reversible female infertility
Helena E. Miettinen, Helen Rayburn and Monty Krieger |
Journal of Clinical Investigation | 2001 |
|
The proper study of mankind
William M. Nauseef |
Journal of Clinical Investigation | 2001 |
|
Decreased lipid synthesis in livers of mice with disrupted Site-1 protease gene
J Yang, JL Goldstein, RE Hammer, YA Moon, MS Brown, JD Horton |
Proceedings of the National Academy of Sciences | 2001 |
|
Growth hormone reduces plasma cholesterol in LDL receptor-deficient mice
M Rudling, B Angelin |
The FASEB Journal | 2001 |
|
SREBP cleavage-activating protein (SCAP) is required for increased lipid synthesis in liver induced by cholesterol deprivation and insulin elevation
M Matsuda, BS Korn, RE Hammer, YA Moon, R Komuro, JD Horton, JL Goldstein, MS Brown, I Shimomura |
Genes & development | 2001 |
|
Evaluation of the Role of Lipoprotein Metabolism Genes in Systemic Cationic Liposome-Mediated Gene TransferIn Vivo
LC Mounkes, W Zhong, HV de Silva, C Handumrongkul, B Desai, E Tse, JM Taylor, RJ Debs |
Human Gene Therapy | 2001 |
|
Essential role for the (hepatic) LDL receptor in macrophage apolipoprotein E-induced reduction in serum cholesterol levels and atherosclerosis
MV Eck |
Atherosclerosis | 2001 |
|
Acute exposure to a high cholesterol diet attenuates myocardial ischemia–reperfusion injury in cholesteryl ester transfer protein mice
SP Jones, WG Girod, KR Marotti, TY Aw, DJ Lefer |
Coronary Artery Disease | 2001 |
|
Genetic Modifiers of Atherosclerosis in Mice
JD Smith, HM Dansky, JL Breslow |
Annals of the New York Academy of Sciences | 2001 |
|
Clinical Significance of Preheparin Serum Lipoprotein Lipase Mass in Coronary Vasospasm
T Hitsumoto, K Yoshinaga, H Noike, M Kanai, K Shirai |
Japanese Circulation Journal | 2001 |
|
The LDL Receptor Gene Family
J Herz |
Neuron | 2001 |
|
Roles of acyl-coenzyme A : cholesterol acyltransferase-1 and -2
TY Chang, CC Chang, S Lin, C Yu, BL Li, A Miyazaki |
Current Opinion in Lipidology | 2001 |
|
Sequencing of the coding exons of the LRP1 and LDLR genes on individual DNA samples reveals novel mutations in both genes
FV Leuven, E Thiry, M Lambrechts, L Stas, T Boon, K Bruynseels, E Muls, O Descamps |
Atherosclerosis | 2001 |
|
Cellular and humoral immune responses to heat shock protein 65 are both involved in promoting fatty-streak formation in LDL-receptor deficient mice
J George, A Afek, B Gilburd, Y Shoenfeld, D Harats |
Journal of the American College of Cardiology | 2001 |
|
Remodeling of the Vessel Wall after Copper-Induced Injury Is Highly Attenuated in Mice with a Total Deficiency of Plasminogen Activator Inhibitor-1
VA Ploplis, I Cornelissen, MJ Sandoval-Cooper, L Weeks, FA Noria, FJ Castellino |
The American Journal of Pathology | 2001 |
|
ACCELERATED ATHEROMA, ANTIPHOSPHOLIPID ANTIBODIES, AND THE ANTIPHOSPHOLIPID SYNDROME
J George, D Haratz, Y Shoenfeld |
Rheumatic Disease Clinics of North America | 2001 |
|
Reduction of atherosclerosis despite hypercholesterolemia in lyn-deficient mice fed a high-fat diet
S Miki, K Horikawa, H Nishizumi, M Suemura, B Sato, M Yamamoto, K Takatsu, T Yamamoto, Y Miki |
Genes to Cells | 2001 |
|
n-3 fatty acids: Antiatherosclerotic effects
R Caterina, A Zampolli |
Lipids | 2001 |
|
Compared with saturated fatty acids, dietary monounsaturated fatty acids and carbohydrates increase atherosclerosis and VLDL cholesterol levels in LDL receptor-deficient, but not apolipoprotein E-deficient, mice
M Merkel, W Velez-Carrasco, LC Hudgins, JL Breslow |
Proceedings of the National Academy of Sciences | 2001 |
|
Direct effect of an acyl-CoA:cholesterol acyltransferase inhibitor, F-1394, on atherosclerosis in apolipoprotein E and low density lipoprotein receptor double knockout mice
T Chiwata, K Aragane, K Fujinami, K Kojima, S Ishibashi, N Yamada, J Kusunoki |
British Journal of Pharmacology | 2001 |
|
Triacylglycerol-rich lipoproteins alter the secretion, and the cholesterol-effluxing function, of apolipoprotein E-containing lipoprotein particles from human (THP-1) macrophages
EM Lindholm, AM Palmer, A Graham |
Biochemical Journal | 2001 |
|
Lifetime correction of genetic deficiency in mice with a single injection of helper-dependent adenoviral vector
IH Kim, A Józkowicz, PA Piedra, K Oka, L Chan |
Proceedings of the National Academy of Sciences | 2001 |
|
Localization of atherosclerosis susceptibility loci to chromosomes 4 and 6 using the Ldlr knockout mouse model
CL Welch, S Bretschger, N Latib, M Bezouevski, Y Guo, N Pleskac, CP Liang, C Barlow, H Dansky, JL Breslow, AR Tall |
Proceedings of the National Academy of Sciences | 2001 |
|
Reduction of atherosclerosis in apolipoprotein E knockout mice by activation of the retinoid X receptor
T Claudel, MD Leibowitz, C Fiévet, A Tailleux, B Wagner, JJ Repa, G Torpier, JM Lobaccaro, JR Paterniti, DJ Mangelsdorf, RA Heyman, J Auwerx |
Proceedings of the National Academy of Sciences | 2001 |
|
LXRs control lipid-inducible expression of the apolipoprotein E gene in macrophages and adipocytes
BA Laffitte, JJ Repa, SB Joseph, DC Wilpitz, HR Kast, DJ Mangelsdorf, P Tontonoz |
Proceedings of the National Academy of Sciences | 2001 |
|
Alternations in hepatic expression of fatty-acid metabolizing enzymes in ArKO mice and their reversal by the treatment with 17β-estradiol or a peroxisome proliferator
K Toda, K Takeda, S Akira, T Saibara, T Okada, S Onishi, Y Shizuta |
The Journal of Steroid Biochemistry and Molecular Biology | 2001 |
|
Cholesterol Signaling at the Endoplasmic Reticulum Occurs in npc1−/− but Not in npc1−/−, LDLR−/− Mice
RP Erickson, M Kiela, WS Garver, K Krishnan, RA Heidenreich |
Biochemical and Biophysical Research Communications | 2001 |
|
Reciprocal Induction of IL-10 and IL-12 from Macrophages by Low-Density Lipoprotein and Its Oxidized Forms
AS Varadhachary, M Monestier, P Salgame |
Cellular Immunology | 2001 |
|
Whole Body Hyperthermia Accelerates Atherogenesis in Low-Density Lipoprotein Receptor Deficient Mice
A Afek, G Keren, D Harats, J George |
Experimental and Molecular Pathology | 2001 |
|
Atherosclerosis and Autoimmunity
EC Lau |
Atherosclerosis and Autoimmunity | 2001 |
|
Degeneration of neurons and glia in the Niemann–Pick C mouse is unrelated to the low-density lipoprotein receptor
DC German, EM Quintero, CL Liang, C Xie, JM Dietschy |
Neuroscience | 2001 |
|
Nutrition in the Prevention and Treatment of Disease
JM Ordovas |
Nutrition in the Prevention and Treatment of Disease | 2001 |
|
The LDL receptor is the major pathway for beta-VLDL uptake by mouse peritoneal macrophages
S Perrey, S Ishibashi, T Kitamine, J Osuga, H Yagyu, Z Chen, F Shionoiri, Y Iizuka, N Yahagi, Y Tamura, K Ohashi, K Harada, T Gotoda, N Yamada |
Atherosclerosis | 2001 |
|
ApoE deficiency compromises the blood brain barrier especially after injury
N Methia, P André, A Hafezi-Moghadam, M Economopoulos, KL Thomas, DD Wagner |
Molecular Medicine | 2001 |
|
Contributions of myeloperoxidase to proinflammatory events: more than an antimicrobial system
W M Nauseef |
International Journal of Hematology | 2001 |
|
A novel cellular phenotype for familial hypercholesterolemia due to a defect in polarized targeting of LDL receptor
U M Koivisto, A L Hubbard, I Mellman |
Cell | 2001 |
|
Lecithin:Cholesterol Acyltransferase Deficiency Increases Atherosclerosis in the Low Density Lipoprotein Receptor and Apolipoprotein E Knockout Mice
JW Furbee, JK Sawyer, JS Parks |
The Journal of biological chemistry | 2001 |
|
Erratum: Apolipoprotein B secretion and atherosclerosis are decreased in mice with phospholipid-transfer protein deficiency
XC Jiang, S Qin, C Qiao, K Kawano, M Lin, A Skold, X Xiao, AR Tall |
Nature Medicine | 2001 |
|
Analysis of Glomerulosclerosis and Atherosclerosis in Lecithin Cholesterol Acyltransferase-deficient Mice
G Lambert, N Sakai, BL Vaisman, EB Neufeld, B Marteyn, CC Chan, B Paigen, E Lupia, A Thomas, LJ Striker, J Blanchette-Mackie, G Csako, JN Brady, R Costello, GE Striker, AT Remaley, HB Brewer, S Santamarina-Fojo |
The Journal of biological chemistry | 2001 |
|
Heme Oxygenase-1 Inhibits Atherosclerotic Lesion Formation in LDL-Receptor Knockout Mice
K Ishikawa, D Sugawara, X Wang, K Suzuki, H Itabe, Y Maruyama, AJ Lusis |
Circulation research | 2001 |
|
7-Ketocholesterol delivered to mice in chylomicron remnant-like particles is rapidly metabolised, excreted and does not accumulate in aorta
MA Lyons, AJ Brown |
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids | 2001 |
|
Lipoprotein Size and Atherosclerosis Susceptibility in Apoe−/− and Ldlr−/− Mice
MM Véniant, S Withycombe, SG Young |
Arteriosclerosis, thrombosis, and vascular biology | 2001 |
|
Long-Term Stable Correction of Low-Density Lipoprotein Receptor–Deficient Mice With a Helper-Dependent Adenoviral Vector Expressing the Very Low-Density Lipoprotein Receptor
K Oka, L Pastore, IH Kim, A Merched, S Nomura, HJ Lee, M Merched-Sauvage, C Arden-Riley, B Lee, M Finegold, A Beaudet, L Chan |
Circulation | 2001 |
|
12/15-Lipoxygenase Gene Disruption Attenuates Atherogenesis in LDL Receptor–Deficient Mice
J George, A Afek, A Shaish, H Levkovitz, N Bloom, T Cyrus, L Zhao, CD Funk, E Sigal, D Harats |
Circulation | 2001 |
|
Physiology of Inflammation
K Ley |
2001 | |
|
Gene Therapy for Acute and Acquired Diseases
P Factor |
2001 | |
|
Hypercholesterolemia Exacerbates Virus-Induced Immunopathologic Liver Disease Via Suppression of Antiviral Cytotoxic T Cell Responses
B Ludewig, M Jäggi, T Dumrese, K Brduscha-Riem, B Odermatt, H Hengartner, RM Zinkernagel |
Journal of immunology (Baltimore, Md. : 1950) | 2001 |
|
Gen-Medizin
AM Raem, RW Braun, H Fenger, W Michaelis, S Nikol, SF Winter |
2001 | |
|
Effects of coexpression of the LDL receptor and apoE on cholesterol metabolism and atherosclerosis in LDL receptor-deficient mice
M Kawashiri, Y Zhang, D Usher, M Reilly, E Puré, DJ Rader |
Journal of lipid research | 2001 |
|
Hepatic lipase overexpression lowers remnant and LDL levels by a noncatalytic mechanism in LDL receptor-deficient mice
HL Dichek, SM Johnson, H Akeefe, GT Lo, E Sage, CE Yap, RW Mahley |
Journal of lipid research | 2001 |
|
A lipoprotein-containing particle is transferred from the serum across the mammary epithelium into the milk of lactating mice
J Monks, PU Huey, L Hanson, RH Eckel, MC Neville, S Gavigan |
Journal of lipid research | 2001 |
|
n-3 fatty acids: antiatherosclerotic effects.
De Caterina R, Zampolli A |
Lipids | 2001 |
|
Defining the atherogenicity of large and small lipoproteins containing apolipoprotein B100
Murielle M. Veniant, Meghan A. Sullivan, Sun K. Kim, Alice Chu, Martha D. Wilson, Marc K. Hellerstein, Lawrence L. Rudel,Rosemary L. Walzem, Stephen G. Young |
Journal of Clinical Investigation | 2000 |
|
Prolonged correction of hyperlipidemia in mice with familial hypercholesterolemia using an adeno-associated viral vector expressing very-low-density lipoprotein receptor
SJ Chen, DJ Rader, J Tazelaar, M Kawashiri, G Gao, JM Wilson |
Molecular Therapy | 2000 |
|
Angiotensin II promotes atherosclerotic lesions and aneurysms in apolipoprotein E–deficient mice
A Daugherty, MW Manning, LA Cassis |
Journal of Clinical Investigation | 2000 |
|
High-level expression of Egr-1 and Egr-1–inducible genes in mouse and human atherosclerosis
TA McCaffrey, C Fu, B Du, S Eksinar, KC Kent, H Bush, K Kreiger, T Rosengart, MI Cybulsky, ES Silverman, T Collins |
Journal of Clinical Investigation | 2000 |
|
The role of the LDL receptor in apolipoprotein B secretion
J Twisk, DL Gillian-Daniel, A Tebon, L Wang, PH Barrett, AD Attie |
Journal of Clinical Investigation | 2000 |
|
Angiotensin II, atherosclerosis, and aortic aneurysms
BC Berk, J Haendeler, J Sottile |
Journal of Clinical Investigation | 2000 |
|
Endothelial dysfunction in atherosclerotic mice: improved relaxation by combined supplementation with L-arginine-tetrahydrobiopterin and enhanced vasoconstriction by endothelin
J Jiang, G Valen, S Tokuno, P Thorén, J Pernow |
British Journal of Pharmacology | 2000 |
|
The effects of N-6 polyunsaturated fatty acid supplementation on the lipid composition and atherogenesis in mouse models of atherosclerosis
J George, M Mulkins, S Casey, R Schatzman, E Sigal, D Harats |
Atherosclerosis | 2000 |
|
Characterization of atherosclerosis in LDL receptor knockout mice: macrophage accumulation correlates with rapid and sustained expression of aortic MCP-1/JE
MC Kowala, R Recce, S Beyer, C Gu, M Valentine |
Atherosclerosis | 2000 |
|
Les animaux génétiquement modifiésÉtude du transport des lipides et de l'athérosclérose
N Baroukh, L Vergnes, M Aostos, M Mzakin, A Ochoa |
Annales de l'Institut Pasteur/Actualités | 2000 |
|
Preheparin serum lipoprotein lipase mass is negatively related to coronary atherosclerosis
T Hitsumoto, H Ohsawa, T Uchi, H Noike, M Kanai, M Yoshinuma, Y Miyashita, H Watanabe, K Shirai |
Atherosclerosis | 2000 |
|
Adenovirus-mediated gene transfer of CTLA4lg gene results in prolonged survival of heart allograft
S Hayashi, M Guang-Lin, I Yokoyama, Y Namii, H Hamada, A Nakao |
Transplant International | 2000 |
|
RNA editing: cytidine to uridine conversion in apolipoprotein B mRNA
A Chester |
Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression | 2000 |
|
Long-term reversal of hypercholesterolemia in low density lipoprotein receptor (LDLR)-deficient mice by adenovirus-mediated LDLR gene transfer combined with CD154 blockade
CS Stein, I Martins, BL Davidson |
The Journal of Gene Medicine | 2000 |
|
Gene therapy for lipid disorders
MK Ma, DJ Rader |
Current controlled trials in cardiovascular medicine | 2000 |
|
Assessment of efficiency and safety of adenovirus mediated gene transfer into normal and damaged murine livers
T Nakatani, S Kuriyama, K Tominaga, T Tsujimoto, A Mitoro, M Yamazaki, H Tsujinoue, H Yoshiji, S Nagao, H Fukui |
Gut | 2000 |
|
Very-low-density lipoprotein binding to the apolipoprotein E receptor 2 is enhanced by lipoprotein lipase, and does not require apolipoprotein E
PJ Tacken, FD Beer, LC Vark, LM Havekes, MH Hofker, WV K |
Biochemical Journal | 2000 |
|
A macrophage receptor for apolipoprotein B48: cloning, expression, and atherosclerosis
ML Brown, MP Ramprasad, PK Umeda, A Tanaka, Y Kobayashi, T Watanabe, H Shimoyamada, WL Kuo, R Li, R Song, WA Bradley, SH Gianturco |
Proceedings of the National Academy of Sciences | 2000 |
|
Lipoprotein lipase- and hepatic triglyceride lipase- promoted very low density lipoprotein degradation proceeds via an apolipoprotein E-dependent mechanism
JD Medh, GL Fry, SL Bowen, S Ruben, H Wong, DA Chappell |
Journal of lipid research | 2000 |
|
Exogenous interferon-gamma enhances atherosclerosis in apolipoprotein E-/- mice
SC Whitman, P Ravisankar, H Elam, A Daugherty |
The American Journal of Pathology | 2000 |
|
Targeted disruption of hormone-sensitive lipase results in male sterility and adipocyte hypertrophy, but not in obesity
J Osuga, S Ishibashi, T Oka, H Yagyu, R Tozawa, A Fujimoto, F Shionoiri, N Yahagi, FB Kraemer, O Tsutsumi, N Yamada |
Proceedings of the National Academy of Sciences | 2000 |
|
P-Selectin or intercellular adhesion molecule (ICAM)-1 deficiency substantially protects against atherosclerosis in apolipoprotein E-deficient mice
RG Collins, R Velji, NV Guevara, MJ Hicks, L Chan, AL Beaudet |
Journal of Experimental Medicine | 2000 |
|
Infectious agents are not necessary for murine atherogenesis
SD Wright, C Burton, M Hernandez, H Hassing, J Montenegro, S Mundt, S Patel, DJ Card, A Hermanowski-Vosatka, JD Bergstrom, CP Sparrow, PA Detmers, YS Chao |
Journal of Experimental Medicine | 2000 |
|
Sulindac inhibits neointimal formation after arterial injury in wild-type and apolipoprotein E-deficient mice
ED Reis, M Roque, H Dansky, JT Fallon, JJ Badimon, C Cordon-Cardo, SJ Shiff, EA Fisher |
Proceedings of the National Academy of Sciences | 2000 |
|
Roles of Cytosolic Phospholipase A2 and Platelet-Activating Factor Receptor in the Ca-Induced Biosynthesis of PAF
H Shindou, S Ishii, N Uozumi, T Shimizu |
Biochemical and Biophysical Research Communications | 2000 |
|
Plasmodium sporozoites invade cells with targeted deletions in the LDL receptor related protein
P Marshall, A Rohlmann, V Nussenzweig, J Herz, P Sinnis |
Molecular and Biochemical Parasitology | 2000 |
|
Autoimmunity in atherosclerosis. The role of autoantigens
J George, D Harats, Y Shoenfeld |
Clinical Reviews in Allergy & Immunology | 2000 |
|
Cholesterol is sequestered in the brains of mice with Niemann-Pick type C disease but turnover is increased
C Xie, DK Burns, SD Turley, JM Dietschy |
Journal of Neuropathology and Experimental Neurology | 2000 |
|
Centripetal cholesterol flow from the extrahepatic organs through the liver is normal in mice with mutated Niemann-Pick type C protein (NPC1)
C Xie, SD Turley, JM Dietschy |
Journal of lipid research | 2000 |
|
Production of Mouse Models for the Study of Human Inborn Errors of Metabolism
JD McDonald |
Molecular Genetics and Metabolism | 2000 |
|
Apolipoprotein E regulates dietary cholesterol absorption and biliary cholesterol excretion: Studies in C57BL/6 apolipoprotein E knockout mice
Ephraim Sehayek, Sarah S. Shefer, Lien B. Nguyen, Jennie G. Ono, Martin Merkel, Jan L. Breslow |
Proceedings of the National Academy of Sciences | 2000 |
|
Macrophage Lipoprotein Lipase Promotes Foam Cell Formation and Atherosclerosis in Low Density Lipoprotein Receptor-deficient Mice
VR Babaev, MB Patel, CF Semenkovich, S Fazio, MR Linton |
The Journal of biological chemistry | 2000 |
|
Analysis of low-density lipoprotein catabolism by primary cultures of hepatic cells from normal and low-density lipoprotein receptor knockout mice
TQ Truong, A Auger, F Denizeau, L Brissette |
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids | 2000 |
|
Autoimmunity in atherosclerosis: lessons from experimental models
J George, A Afek, B Gilburd, D Harats, Y Shoenfeld |
Lupus | 2000 |
|
Apolipoprotein E receptors: linking brain development and alzheimer's disease
J Herz, U Beffert |
Nature Reviews Neuroscience | 2000 |
|
Hepatic microvascular responses to ischemia-reperfusion in low-density lipoprotein receptor knockout mice
N Mori, Y Horie, Y Nimura, R Wolf, DN Granger |
AJP Gastrointestinal and Liver Physiology | 2000 |
|
In Vivo Adenovirus-Mediated Suicide Gene Therapy of Orthotopic Bladder Cancer
MA Sutton, CT Freund, SA Berkman, TD Dang, MW Kattan, TM Wheeler, DR Rowley, SP Lemer |
Molecular Therapy | 2000 |
|
Overexpression of 15-Lipoxygenase in Vascular Endothelium Accelerates Early Atherosclerosis in LDL Receptor–Deficient Mice
D Harats, A Shaish, J George, M Mulkins, H Kurihara, H Levkovitz, E Sigal |
Arteriosclerosis, thrombosis, and vascular biology | 2000 |
|
Prominent Role of P-Selectin in the Development of Advanced Atherosclerosis in ApoE-Deficient Mice
ZM Dong, AA Brown, DD Wagner |
Circulation | 2000 |
|
Low Density Lipoprotein Receptor of Macrophages Facilitates Atherosclerotic Lesion Formation in C57Bl/6 Mice
N Herijgers, MV Eck, PH Groot, PM Hoogerbrugge, TJ Berkel |
Arteriosclerosis, thrombosis, and vascular biology | 2000 |
|
Adoptive Transfer of β 2 -Glycoprotein I–Reactive Lymphocytes Enhances Early Atherosclerosis in LDL Receptor–Deficient Mice
J George, D Harats, B Gilburd, A Afek, A Shaish, J Kopolovic, Y Shoenfeld |
Circulation | 2000 |
|
ICAM-1 Deficiency Reduces Atherosclerotic Lesions in Double-Knockout Mice (ApoE −/− /ICAM-1 −/− ) Fed a Fat or a Chow Diet
MC Bourdillon, RN Poston, C Covacho, E Chignier, G Bricca, JL McGregor |
Arteriosclerosis, thrombosis, and vascular biology | 2000 |
|
Pharmacological and genetic modifications of somatic cholesterol do not substantially alter the course of CNS disease in Niemann-Pick C mice
RP Erickson, WS Garver, F Camargo, GS Hossian, RA Heidenreich |
Journal of Inherited Metabolic Disease | 2000 |
|
Lipoprotein Metabolism and Atherogenesis
T Kita, M Yokode |
2000 | |
|
Hypothalamic-pituitary-adrenal dysfunction in Apoe(-/-) mice: possible role in behavioral and metabolic alterations
J Raber, S F Akana, S Bhatnagar, M F Dallman, D Wong, L Mucke |
The Journal of neuroscience : the official journal of the Society for Neuroscience | 2000 |
|
Polymorphism of class A scavenger receptors in C57BL/6 mice
A Daugherty, SC Whitman, AE Block, DL Rateri |
Journal of lipid research | 2000 |
|
LDL receptor deficiency unmasks altered VLDL triglyceride metabolism in VLDL receptor transgenic and knockout mice
PJ Tacken, B Teusink, MC Jong, D Harats, LM Havekes, KW van Dijk, MH Hofker |
Journal of lipid research | 2000 |
|
Relative importance of the LDL receptor and scavenger receptor class B in the β-VLDL-induced uptake and accumulation of cholesteryl esters by peritoneal macrophages
N Herijgers, MV Eck, SJ Korporaal, PM Hoogerbrugge, TJ Berkel |
Journal of lipid research | 2000 |
|
Role of Acyl-Coenzyme A:Cholesterol Acyltransferase-1 in the Control of Hepatic Very Low Density Lipoprotein Secretion and Low Density Lipoprotein Receptor Expression in the Mouse and Hamster
DK Spady, MN Willard, RS Meidell |
The Journal of biological chemistry | 2000 |
|
HNF4 and COUP-TFII interact to modulate transcription of the cholesterol 7α-hydroxylase gene (CYP7A1)
D Stroup, JY Chiang |
Journal of lipid research | 2000 |
|
A sensitive and convenient method for lipoprotein profile analysis of individual mouse plasma samples
DW Garber, KR Kulkarni, GM Anantharamaiah |
Journal of lipid research | 2000 |
|
Genetic modifiers of atherosclerosis in mice.
Knowles JW, Maeda N |
Arteriosclerosis, thrombosis, and vascular biology | 2000 |
|
Sterol regulatory element-binding protein-1 as a key transcription factor for nutritional induction of lipogenic enzyme genes
H Shimano, JD Horton, RE Hammer, I Shimomura, MS Brown, JL Goldstein |
Journal of Clinical Investigation | 1999 |
|
The atherogenic effects of chlamydia are dependent on serum cholesterol and specific to Chlamydia pneumoniae
H Hu, GN Pierce, G Zhong |
Journal of Clinical Investigation | 1999 |
|
MCP-1 deficiency reduces susceptibility to atherosclerosis in mice that overexpress human apolipoprotein B
J Gosling, S Slaymaker, L Gu, S Tseng, CH Zlot, SG Young, BJ Rollins, IF Charo |
Journal of Clinical Investigation | 1999 |
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Disruption of the 12/15-lipoxygenase gene diminishes atherosclerosis in apo E–deficient mice
T Cyrus, JL Witztum, DJ Rader, R Tangirala, S Fazio, MF Linton, CD Funk |
Journal of Clinical Investigation | 1999 |
|
Apo E structure determines VLDL clearance and atherosclerosis risk in mice
C Knouff, ME Hinsdale, H Mezdour, MK Altenburg, M Watanabe, SH Quarfordt, PM Sullivan, N Maeda |
Journal of Clinical Investigation | 1999 |
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Disruption of LDL receptor gene in transgenic SREBP-1a mice unmasks hyperlipidemia resulting from production of lipid-rich VLDL
JD Horton, H Shimano, RL Hamilton, MS Brown, JL Goldstein |
Journal of Clinical Investigation | 1999 |
|
Apo A-I inhibits foam cell formation in apo E–deficient mice after monocyte adherence to endothelium
HM Dansky, SA Charlton, CB Barlow, M Tamminen, JD Smith, JS Frank, JL Breslow |
Journal of Clinical Investigation | 1999 |
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Regulation of mevalonate synthesis in low density lipoprotein receptor knockout mice fed n-3 or n-6 polyunsaturated fatty acids
A El-Sohemy, MC Archer |
Lipids | 1999 |
|
Gene therapy for dyslipidemia: Clinical prospects
DJ Rader, UJ Tietge |
Current Atherosclerosis Reports | 1999 |
|
Enhanced phenylephrine-induced rhythmic activity in the atherosclerotic mouse aortaviaan increase in opening of KCachannels: relation to Kvchannels and nitric oxide
J Jiang, P Thorén, G Caligiuri, GK Hansson, J Pernow |
British Journal of Pharmacology | 1999 |
|
Influence of the HDL receptor SR-BI on atherosclerosis
M Krieger, K Kozarsky |
Current Opinion in Lipidology | 1999 |
|
Upregulation of selective cholesteryl ester uptake pathway in mice with deletion of low-density lipoprotein receptor function
S Azhar, Y Luo, S Medicherla, E Reaven |
Journal of Cellular Physiology | 1999 |
|
Molecular biology and gene transfer in atherosclerosis in the stenting era
NM Caplice, RD Simari, DR Holmes |
Acute Cardiac Care | 1999 |
|
Control of Erythropoietin Secretion by Doxycycline or Mifepristone in Mice Bearing Polymer-Encapsulated Engineered Cells
C Serguera, D Bohl, E Rolland, P Prevost, JM Heard |
Human Gene Therapy | 1999 |
|
Gene therapy for atherosclerosis and atherosclerosis-related diseases
T Pakkanen, S Ylä-Herttuala |
Current Atherosclerosis Reports | 1999 |
|
The Involvement of β2-Glycoprotein I (β2-GPI) in Human and Murine Atherosclerosis
J George, Y Shoenfeld, D Harats |
Journal of Autoimmunity | 1999 |
|
Murine Mentors: Transgenic and Knockout Models of Surgical Disease
JM Arbeit, R Hirose |
Annals of Surgery | 1999 |
|
Presence of telomeric G-strand tails in the telomerase catalytic subunit TERT knockout mice
X Yuan, S Ishibashi, S Hatakeyama, M Saito, J Nakayama, R Nikaido, T Haruyama, Y Watanabe, H Iwata, M Iida, H Sugimura, N Yamada, F Ishikawa |
Genes to Cells | 1999 |
|
Leukocyte adhesion molecules in atherogenesis
MI Cybulsky, AH Lichtman, L Hajra, K Iiyama |
Clinica Chimica Acta | 1999 |
|
Primordial Prevention of Cardiovascular Disease through Applied Genetics
RR Williams, PN Hopkins, S Stephenson, L Wu, SC Hunt |
Preventive Medicine | 1999 |
|
Analysis of a Novel Mechanism of Neuronal Toxicity Produced by an Apolipoprotein E-Derived Peptide
KL Moulder, M Narita, LK Chang, G Bu, EM Johnson |
Journal of Neurochemistry | 1999 |
|
Construction and in Vitro Functional Evaluation of a Low-Density Lipoprotein Receptor/Transferrin Fusion Protein as a Therapeutic Tool for Familial Hypercholesterolemia
F Parise, L Simone, MA Croce, M Ghisellini, R Battini, S Borghi, R Tiozzo, S Ferrari, S Calandra, S Ferrari |
Human Gene Therapy | 1999 |
|
Use of a Liver-Specific Promoter Reduces Immune Response to the Transgene in Adenoviral Vectors
L Pastore, N Morral, H Zhou, R Garcia, RJ Parks, S Kochanek, FL Graham, B Lee, AL Beaudet |
Human Gene Therapy | 1999 |
|
PEGylation of Adenovirus with Retention of Infectivity and Protection from Neutralizing Antibody in Vitro and in Vivo
CR O'Riordan, A Lachapelle, C Delgado, V Parkes, SC Wadsworth, AE Smith, GE Francis |
Human Gene Therapy | 1999 |
|
Mouse very low-density lipoprotein receptor (VLDLR): gene structure, tissue-specific expression and dietary and developmental regulation
O Tiebel, K Oka, K Robinson, M Sullivan, J Martinez, M Nakamuta, K Ishimura-Oka, L Chan |
Atherosclerosis | 1999 |
|
Reeler/Disabled-like Disruption of Neuronal Migration in Knockout Mice Lacking the VLDL Receptor and ApoE Receptor 2
M Trommsdorff, M Gotthardt, T Hiesberger, J Shelton, W Stockinger, J Nimpf, RE Hammer, JA Richardson, J Herz |
Cell | 1999 |
|
Gene Therapy for Cerebrovascular Disease
C Weihl, RL Macdonald, M Stoodley, J L??ders, G Lin |
Neurosurgery | 1999 |
|
Localization of Niemann-Pick C1 protein in astrocytes: implications for neuronal degeneration in Niemann- Pick type C disease
SC Patel, S Suresh, U Kumar, CY Hu, A Cooney, EJ Blanchette-Mackie, EB Neufeld, RC Patel, RO Brady, YC Patel, PG Pentchev, WY Ong |
Proceedings of the National Academy of Sciences | 1999 |
|
Cholesterol accumulation in tissues of the Niemann-pick type C mouse is determined by the rate of lipoprotein-cholesterol uptake through the coated-pit pathway in each organ
C Xie, SD Turley, JM Dietschy |
Proceedings of the National Academy of Sciences | 1999 |
|
A role for apoE in regulating the levels of alpha-1-antichymotrypsin in the aging mouse brain and in Alzheimer's disease
F Licastro, IL Campbell, C Kincaid, I Veinbergs, EV Uden, E Rockenstein, M Mallory, JR Gilbert, E Masliah |
The American Journal of Pathology | 1999 |
|
Insulin selectively increases SREBP-1c mRNA in the livers of rats with streptozotocin-induced diabetes
I Shimomura, Y Bashmakov, S Ikemoto, JD Horton, MS Brown, JL Goldstein |
Proceedings of the National Academy of Sciences | 1999 |
|
Reversal of hyperlipidaemia in apolipoprotein C1 transgenic mice by adenovirus-mediated gene delivery of the low-density-lipoprotein receptor, but not by the very-low-density-lipoprotein receptor
MC Jong, KW van Dijk, VE Dahlmans, HV der Boom, K Kobayashi, K Oka, G Siest, L Chan, MH Hofker, LM Havekes |
Biochemical Journal | 1999 |
|
Murine mentors: transgenic and knockout models of surgical disease
JM Arbeit, R Hirose |
Annals of Surgery | 1999 |
|
Decreased selective uptake of high density lipoprotein cholesteryl esters in apolipoprotein E knock-out mice
T Arai, F Rinninger, L Varban, V Fairchild-Huntress, CP Liang, W Chen, T Seo, R Deckelbaum, D Huszar, AR Tall |
Proceedings of the National Academy of Sciences | 1999 |
|
Myocardial infarction mediated by endothelin receptor signaling in hypercholesterolemic mice
G Caligiuri, B Levy, J Pernow, P Thorén, GK Hansson |
Proceedings of the National Academy of Sciences | 1999 |
|
Macrophages, lipoprotein metabolism, and atherosclerosis: insights from murine bone marrow transplantation studies
MR Linton, S Fazio |
Current Opinion in Lipidology | 1999 |
|
Somatic gene therapy for dyslipidemias
M Belalcazar, L Chan |
Journal of Laboratory and Clinical Medicine | 1999 |
|
Localization of Niemann-Pick C1 protein in astrocytes: Implications for neuronal degeneration in Niemann- Pick type C disease
SC Patel, S Suresh, U Kumar, CY Hu, A Cooney, EJ Blanchette-Mackie, EB Neufeld, RC Patel, RO Brady, YC Patel, PG Pentchev, WY Ong |
Proceedings of the National Academy of Sciences | 1999 |
|
Charting the fate of the "good cholesterol": identification and characterization of the high-density lipoprotein receptor SR-BI
M Krieger |
Annual Review of Biochemistry | 1999 |
|
A direct role for the macrophage low density lipoprotein receptor in atherosclerotic lesion formation
MF Linton, VR Babaev, LA Gleaves, S Fazio |
The Journal of biological chemistry | 1999 |
|
Decreased atherosclerosis in heterozygous low density lipoprotein receptor-deficient mice expressing the scavenger receptor BI transgene
T Arai, N Wang, M Bezouevski, C Welch, AR Tall |
The Journal of biological chemistry | 1999 |
|
Sterol regulatory element-binding protein-1 as a key transcription factor for nutritional induction of lipogenic enzyme genes
H Shimano, JD Horton, RE Hammer, I Shimomura, MS Brown, JL Goldstein |
Journal of Biological Chemistry | 1999 |
|
Increased levels of nuclear SREBP-1c associated with fatty livers in two mouse models of diabetes mellitus
I Shimomura, Y Bashmakov, JD Horton |
The Journal of biological chemistry | 1999 |
|
Generation of monoclonal antibodies specific for mouse apolipoprotein B-100 in apolipoprotein B-48-only mice
CH Zlot, LM Flynn, MM Véniant, E Kim, M Raabe, SP McCormick, P Ambroziak, LM McEvoy, SG Young |
Journal of lipid research | 1999 |
|
Overexpression of human apolipoprotein A-II in mice induces hypertriglyceridemia due to defective very low density lipoprotein hydrolysis
E Boisfer, G Lambert, V Atger, NQ Tran, D Pastier, C Benetollo, JF Trottier, I Beaucamps, M Antonucci, M Laplaud, S Griglio, J Chambaz, AD Kalopissis |
The Journal of biological chemistry | 1999 |
|
An extrahepatic receptor-associated protein-sensitive mechanism is involved in the metabolism of triglyceride-rich lipoproteins
BJ van Vlijmen, A Rohlmann, ST Page, A Bensadoun, IS Bos, TJ van Berkel, LM Havekes, J Herz |
The Journal of biological chemistry | 1999 |
|
Mediation of L-arginine-induced retardation of hypercholesterolemic atherosclerosis in rabbits by antioxidant mechanisms
SV Mantha |
Nutrition Research | 1999 |
|
Atherosclerosis in low density lipoprotein receptor knockout mice fed cholesterol and soybean oil
A Mortensen, P Olsen, H Frandsen |
Nutrition Research | 1999 |
|
Thérapie génique des maladies héréditaires du foie
N Ferry |
Annales de l'Institut Pasteur/Actualités | 1999 |
|
Embryonic lethality and defective neural tube closure in mice lacking squalene synthase
R Tozawa, S Ishibashi, J Osuga, H Yagyu, T Oka, Z Chen, K Ohashi, S Perrey, F Shionoiri, N Yahagi, K Harada, T Gotoda, Y Yazaki, N Yamada |
The Journal of biological chemistry | 1999 |
|
Recycling of Apolipoprotein E in Mouse Liver
S Fazio, MR Linton, AH Hasty, LL Swift |
The Journal of biological chemistry | 1999 |
|
Lipoprotein receptors: new roles for ancient proteins
TE Willnow, A Nykjaer, J Herz |
Nature Cell Biology | 1999 |
|
Acetylcholine-Induced Response of Coronary Resistance Arterioles in Cholesterol-Fed Rabbits
K Takahashi, M Ohyanagi, K Ikeoka, T Iwasaki |
The Japanese Journal of Pharmacology | 1999 |
|
Unique Cellular Events Occurring during the Initial Interaction of Macrophages with Matrix-retained or Methylated Aggregated Low Density Lipoprotein (LDL): PROLONGED CELL-SURFACE CONTACT DURING WHICH LDL-CHOLESTERYL ESTER HYDROLYSIS EXCEEDS LDL PROTEIN DEGRADATION
X Buton, Z Mamdouh, R Ghosh, H Du, G Kuriakose, N Beatini, GA Grabowski, FR Maxfield, I Tabas |
The Journal of biological chemistry | 1999 |
|
Inhibition of adenovirus-mediated gene transfer by bronchoalveolar lavage fluid
A Bastian, B Bewig |
Gene Therapy | 1999 |
|
Ischemia-reperfusion induced microvascular responses in LDL-receptor −/− mice
N Mori, Y Horie, ME Gerritsen, DN Granger |
American journal of physiology. Heart and circulatory physiology | 1999 |
|
Genetic differences in cholesterol absorption in 129/Sv and C57BL/6 mice: effect on cholesterol responsiveness
CD Jolley, JM Dietschy, SD Turley |
AJP Gastrointestinal and Liver Physiology | 1999 |
|
Analysis of Expression of Genes Involved in Apolipoprotein E-Based Lipoprotein Metabolism in Pregnant Mice Deficient in the Receptor-Associated Protein, the Low Density Lipoprotein Receptor, or Apolipoprotein E1
L Umans, L Overbergh, L Serneels, I Tesseur, FV Leuven |
Biology of reproduction | 1999 |
|
Transient cyclophosphamide treatment before intraportal readministration of an adenoviral vector can induce re-expression of the original gene construct in rat liver
S Kuriyama, K Tominaga, M Kikukawa, T Tsujimoto, T Nakatani, H Tsujinoue, H Okuda, S Nagao, A Mitoro, H Yoshiji, H Fukui |
Gene Therapy | 1999 |
|
Insights into Apolipoprotein B Biology from Transgenic and Gene-Targeted Mice
MM Véniant, E Kim, S McCormick, J Borén, LB Nielsen, M Raabe, SG Young |
The Journal of nutrition | 1999 |
|
Effects of Hypercholesterolemia on Myocardial Ischemia-Reperfusion Injury in LDL Receptor–Deficient Mice
WG Girod, SP Jones, N Sieber, TY Aw, DJ Lefer |
Arteriosclerosis, thrombosis, and vascular biology | 1999 |
|
Patterns of Vascular Cell Adhesion Molecule-1 and Intercellular Adhesion Molecule-1 Expression in Rabbit and Mouse Atherosclerotic Lesions and at Sites Predisposed to Lesion Formation
K Iiyama, L Hajra, M Iiyama, H Li, M DiChiara, BD Medoff, MI Cybulsky |
Circulation research | 1999 |
|
Hyperlipidemia of ApoE2(Arg 158 -Cys) and ApoE3-Leiden Transgenic Mice Is Modulated Predominantly by LDL Receptor Expression
KW van Dijk, BJ van Vlijmen, MP de Winther, B van t Hof, A van der Zee, H van der Boom, LM Havekes, MH Hofker |
Arteriosclerosis, thrombosis, and vascular biology | 1999 |
|
Monocyte Rolling in Early Atherogenesis: Vital Role in Lesion Development
DJ Lefer, DN Granger |
Circulation research | 1999 |
|
Hyperlipidemia and Atherosclerotic Lesion Development in LDL Receptor–Deficient Mice Fed Defined Semipurified Diets With and Without Cholate
AH Lichtman, SK Clinton, K Iiyama, PW Connelly, P Libby, MI Cybulsky |
Arteriosclerosis, thrombosis, and vascular biology | 1999 |
|
Contemporary Concepts in Cardiology
R Gorlin, G Dangas, PK Toutouzas, MM Konstadoulakis |
1999 | |
|
In LDL receptor-deficient mice, catabolism of remnant lipoproteins requires a high level of apoE but is inhibited by excess apoE
KW van Dijk, BJ van Vlijmen, HB van't Hof, A van der Zee, S Santamarina-Fojo, TJ van Berkel, LM Havekes, MH Hofker |
Journal of lipid research | 1999 |
|
Apolipoprotein E knock-out mice are highly susceptible to endotoxemia and Klebsiella pneumoniae infection
N de Bont, MG Netea, PN Demacker, I Verschueren, BJ Kullberg, KW van Dijk, JW van der Meer, AF Stalenhoef |
Journal of lipid research | 1999 |
|
Recombinant adenovirus vectors for cytokine gene therapy in mice
H Kurata, CB Liu, J Valkova, AE Koch, H Yssel, Y Hirabayashi, T Inoue, T Yokota, K Arai |
Journal of Allergy and Clinical Immunology | 1999 |
|
Dissection of the complex role of apolipoprotein E in lipoprotein metabolism and atherosclerosis using mouse models
KW van Dijk, MH Hofker, LM Havekes |
Current Atherosclerosis Reports | 1999 |
|
An apolipoprotein E synthetic peptide targets to lipoproteins in plasma and mediates both cellular lipoprotein interactions in vitro and acute clearance of cholesterol-rich lipoproteins in vivo
IR Nikoulin, LK Curtiss |
Journal of Clinical Investigation | 1998 |
|
Cholesterol lowering in low density lipoprotein receptor knockout mice overexpressing apolipoprotein E
J Osuga, M Yonemoto, N Yamada, H Shimano, H Yagyu, K Ohashi, K Harada, T Kamei, Y Yazaki, S Ishibashi |
Journal of Clinical Investigation | 1998 |
|
Immunoglobulin treatment reduces atherosclerosis in apo E knockout mice
A Nicoletti, S Kaveri, G Caligiuri, J Bariéty, GK Hansson |
Journal of Clinical Investigation | 1998 |
|
Hypercholesterolemia is associated with a T helper (Th) 1/Th2 switch of the autoimmune response in atherosclerotic apo E-knockout mice
X Zhou, G Paulsson, S Stemme, GK Hansson |
Journal of Clinical Investigation | 1998 |
|
Inducible inactivation of hepatic LRP gene by cre-mediated recombination confirms role of LRP in clearance of chylomicron remnants
A Rohlmann, M Gotthardt, RE Hammer, J Herz |
Journal of Clinical Investigation | 1998 |
|
Fibrinogen deficiency is compatible with the development of atherosclerosis in mice
Q Xiao, MJ Danton, DP Witte, MC Kowala, MT Valentine, JL Degen |
Journal of Clinical Investigation | 1998 |
|
Vascular expression of extracellular superoxide dismutase in atherosclerosis
T Fukai, ZS Galis, XP Meng, S Parthasarathy, DG Harrison |
Journal of Clinical Investigation | 1998 |
|
Hepatic apo E expression is required for remnant lipoprotein clearance in the absence of the low density lipoprotein receptor
MF Linton, AH Hasty, VR Babaev, S Fazio |
Journal of Clinical Investigation | 1998 |
|
Type III hyperlipoproteinemia and spontaneous atherosclerosis in mice resulting from gene replacement of mouse Apoe with human Apoe*2
PM Sullivan, H Mezdour, SH Quarfordt, N Maeda |
Journal of Clinical Investigation | 1998 |
|
The combined role of P- and E-selectins in atherosclerosis
ZM Dong, SM Chapman, AA Brown, PS Frenette, RO Hynes, DD Wagner |
Journal of Clinical Investigation | 1998 |
|
Substitution of the carboxyl-terminal domain of apo AI with apo AII sequences restores the potential of HDL to reduce the progression of atherosclerosis in apo E knockout mice
P Holvoet, S Danloy, E Deridder, M Lox, H Bernar, A Dhoest, D Collen |
Journal of Clinical Investigation | 1998 |
|
Lipoprotein clearance mechanisms in LDL receptor-deficient "Apo-B48-only" and "Apo-B100-only" mice
MM Véniant, CH Zlot, RL Walzem, V Pierotti, R Driscoll, D Dichek, J Herz, SG Young |
Journal of Clinical Investigation | 1998 |
|
Blunted feedback suppression of SREBP processing by dietary cholesterol in transgenic mice expressing sterol-resistant SCAP(D443N)
BS Korn, I Shimomura, Y Bashmakov, RE Hammer, JD Horton, JL Goldstein, MS Brown |
Journal of Clinical Investigation | 1998 |
|
Increased sphingomyelin content of plasma lipoproteins in apolipoprotein E knockout mice reflects combined production and catabolic defects and enhances reactivity with mammalian sphingomyelinase
T Jeong, SL Schissel, I Tabas, HJ Pownall, AR Tall, X Jiang |
Journal of Clinical Investigation | 1998 |
|
Receptor-mediated mechanisms of lipoprotein remnant catabolism
DA Chappell, JD Medh |
Progress in Lipid Research | 1998 |
|
Reduction of atherosclerosis in mice by inhibition of CD40 signalling
F Mach, U Schönbeck, GK Sukhova, E Atkinson, P Libby |
Nature | 1998 |
|
Gene Therapy with Bilirubin-UDP-Glucuronosyltransferase in the Gunn Rat Model of Crigler-Najjar Syndrome Type 1
Q Li, SS Murphree, SS Willer, R Bolli, BA French |
Human Gene Therapy | 1998 |
|
LIPOPROTEINS AND ATHEROGENESIS
JM Hoeg |
Endocrinology & Metabolism Clinics of North America | 1998 |
|
Biochemical and molecular aspects of genetic disorders of bilirubin metabolism
T Iyanagi, Y Emi, S Ikushiro |
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease | 1998 |
|
A mouse model of human familial hypercholesterolemia: Markedly elevated low density lipoprotein cholesterol levels and severe atherosclerosis on a low-fat chow diet
L Powell-Braxton, M Véniant, RD Latvala, KI Hirano, WB Won, J Ross, N Dybdal, CH Zlot, SG Young, NO Davidson |
Nature Medicine | 1998 |
|
Characterization of atherosclerotic lesions in apo E3-leiden transgenic mice
P Leppänen, JS Luoma, MH Hofker, LM Havekes, S Ylä-Herttuala |
Atherosclerosis | 1998 |
|
Effect of adeno-associated virus-mediated transfer of low density lipoprotein receptor gene on treatment of hypercholesterolemia
G Chen, L Song, X Zhu, X Zhang, C Zhang, T Wang, J Tang |
Science in China Series C: Life Sciences | 1998 |
|
La souris: un modèle et un outil pour la compréhension des maladies humaines
R Erickson |
Annales de l'Institut Pasteur/Actualités | 1998 |
|
Effect of probucol on serum lipids, atherosclerosis and toxicology in fat-fed LDL receptor deficient mice
GM Benson, R Schiffelers, C Nicols, J Latcham, M Vidgeon-Hart, CD Toseland, KE Suckling, PH Groot |
Atherosclerosis | 1998 |
|
Development of engineered cells for implantation in gene therapy
PL Chang, KM Bowie |
Advanced Drug Delivery Reviews | 1998 |
|
High Doses of a Helper-Dependent Adenoviral Vector Yield Supraphysiological Levels ofα1-Antitrypsin with Negligible Toxicity
N Morral, RJ Parks, H Zhou, C Langston, G Schiedner, J Quinones, FL Graham, S Kochanek, AL Beaudet |
Human Gene Therapy | 1998 |
|
Triglyceride metabolism in heterozygote of Watanabe heritable hyperlipidemic rabbit
Y Naka, G Yoshino, T Hirano, Y Murata, E Maeda, T Kazumi, M Kasuga |
Atherosclerosis | 1998 |
|
Liver-Directed Gene Transfer Vectors
N Ferry, JM Heard |
Human Gene Therapy | 1998 |
|
Evaluating the Potential of Germ Line Transmission after Intravenous Administration of Recombinant Adenovirus in the C3H Mouse
X Ye, GP Gao, C Pabin, SE Raper, JM Wilson |
Human Gene Therapy | 1998 |
|
Effect of reduced low-density lipoprotein receptor level on HepG2 cell cholesterol metabolism
L Izem, E Rassart, L Kamate, L Falstrault, D Rhainds, L Brissette |
Biochemical Journal | 1998 |
|
Endothelin ETA receptor blockade restores NO-mediated endothelial function and inhibits atherosclerosis in apolipoprotein E-deficient mice
M Barton, CC Haudenschild, LV d'Uscio, S Shaw, K Münter, TF Lüscher |
Proceedings of the National Academy of Sciences | 1998 |
|
Antiatherogenic effects of the antioxidant BO-653 in three different animal models
O Cynshi, Y Kawabe, T Suzuki, Y Takashima, H Kaise, M Nakamura, Y Ohba, Y Kato, K Tamura, A Hayasaka, A Higashida, H Sakaguchi, M Takeya, K Takahashi, K Inoue, N Noguchi, E Niki, T Kodama |
Proceedings of the National Academy of Sciences | 1998 |
|
Expression of heme oxygenase-1 in atherosclerotic lesions
LJ Wang, TS Lee, FY Lee, RC Pai, LY Chau |
The American Journal of Pathology | 1998 |
|
Low density lipoprotein receptor-negative mice expressing human apolipoprotein B-100 develop complex atherosclerotic lesions on a chow diet: no accentuation by apolipoprotein(a)
DA Sanan, DL Newland, R Tao, S Marcovina, J Wang, V Mooser, RE Hammer, HH Hobbs |
Proceedings of the National Academy of Sciences | 1998 |
|
Insulin resistance and diabetes mellitus in transgenic mice expressing nuclear SREBP-1c in adipose tissue: model for congenital generalized lipodystrophy
I Shimomura, RE Hammer, JA Richardson, S Ikemoto, Y Bashmakov, JL Goldstein, MS Brown |
Genes & development | 1998 |
|
Low-dose expression of a human apolipoprotein E transgene in macrophages restores cholesterol efflux capacity of apolipoprotein E-deficient mouse plasma
Y Zhu, S Bellosta, C Langer, F Bernini, RE Pitas, RW Mahley, G Assmann, A Eckardstein |
Proceedings of the National Academy of Sciences | 1998 |
|
Apolipoprotein J (clusterin) induces cholesterol export from macrophage-foam cells: a potential anti-atherogenic function?
IC Gelissen, T Hochgrebe, MR Wilson, SB Easterbrook-Smith, W Jessup, RT Dean, AJ Brown |
Biochemical Journal | 1998 |
|
Lamellar lipoproteins uniquely contribute to hyperlipidemia in mice doubly deficient in apolipoprotein E and hepatic lipase
N Bergeron, L Kotite, M Verges, P Blanche, RL Hamilton, RM Krauss, A Bensadoun, RJ Havel |
Proceedings of the National Academy of Sciences | 1998 |
|
Principles of Medical Biology
JO Jørgensen |
Principles of Medical Biology | 1998 |
|
The Gene Knockout FactsBook
TW Mak, J Penninger, J Roder, J Rossant, M Saunders |
The Gene Knockout FactsBook | 1998 |
|
Ten steps to gene therapy for cardiovascular diseases
CD Rios, Y Chu, BL Davidson, DD Heistad |
Journal of Laboratory and Clinical Medicine | 1998 |
|
Low density lipoprotein receptor-negative mice expressing human apolipoprotein B-100 develop complex atherosclerotic lesions on a chow diet: No accentuation by apolipoprotein(a)
DA Sanan, DL Newland, R Tao, S Marcovina, J Wang, V Mooser, RE Hammer, HH Hobbs |
Proceedings of the National Academy of Sciences | 1998 |
|
Leukocyte-endothelium adhesion molecules in atherosclerosis
ZM Dong, DD Wagner |
Journal of Laboratory and Clinical Medicine | 1998 |
|
Apolipoprotein E2 reduces the low density lipoprotein level in transgenic mice by impairing lipoprotein lipase-mediated lipolysis of triglyceride-rich lipoproteins
Y Huang, XQ Liu, SC Rall, RW Mahley |
The Journal of biological chemistry | 1998 |
|
Dietary monounsaturated fatty acids promote aortic atherosclerosis in LDL receptor-null, human ApoB100-overexpressing transgenic mice
LL Rudel, K Kelley, JK Sawyer, R Shah, MD Wilson |
Arteriosclerosis, thrombosis, and vascular biology | 1998 |
|
Cholesterol metabolism and embryogenesis
RV Farese, J Herz |
Trends in genetics : TIG | 1998 |
|
Temporal and spatial pattern of expression of the HDL receptor SR-BI during murine embryogenesis
B Trigatti, H Rayburn, M Viñals, A Braun, H Miettinen, M Penman, M Hertz, M Schrenzel, L Amigo, A Rigotti, M Krieger |
Journal of lipid research | 1998 |
|
Centripetal cholesterol flux to the liver is dictated by events in the peripheral organs and not by the plasma high density lipoprotein or apolipoprotein A-I concentration
M Krieger |
Journal of lipid research | 1998 |
|
Cholesterol and bile acid metabolism are impaired in mice lacking the nuclear oxysterol receptor LXR alpha
DJ Peet, SD Turley, W Ma, BA Janowski, JM Lobaccaro, RE Hammer, DJ Mangelsdorf |
Cell | 1998 |
|
Absence of monocyte chemoattractant protein-1 reduces atherosclerosis in low density lipoprotein receptor-deficient mice
L Gu, Y Okada, SK Clinton, C Gerard, GK Sukhova, P Libby, BJ Rollins |
Molecular Cell | 1998 |
|
Immunization of LDL Receptor Deficient Mice With Homologous Malondialdehyde-Modified and Native LDL Reduces Progression of Atherosclerosis by Mechanisms Other Than Induction of High Titers of Antibodies to Oxidative Neoepitopes
S Freigang, S Horkko, E Miller, JL Witztum, W Palinski |
Arteriosclerosis, thrombosis, and vascular biology | 1998 |
|
Dual mechanisms for the low plasma levels of truncated apolipoprotein B proteins in familial hypobetalipoproteinemia. Analysis of a new mouse model with a nonsense mutation in the Apob gene
E Kim, C M Cham, M M Véniant, P Ambroziak, S G Young |
Journal of Clinical Investigation | 1998 |
|
Secretory Sphingomyelinase, a Product of the Acid Sphingomyelinase Gene, Can Hydrolyze Atherogenic Lipoproteins at Neutral pH: IMPLICATIONS FOR ATHEROSCLEROTIC LESION DEVELOPMENT
SL Schissel, X Jiang, J Tweedie-Hardman, T Jeong, EH Camejo, J Najib, JH Rapp, KJ Williams, I Tabas |
The Journal of biological chemistry | 1998 |
|
Overexpression of Cholesterol 7α-Hydroxylase (CYP7A) in Mice Lacking the Low Density Lipoprotein (LDL) Receptor Gene: LDL TRANSPORT AND PLASMA LDL CONCENTRATIONS ARE REDUCED
DK Spady, JA Cuthbert, MN Willard, RS Meidell |
The Journal of biological chemistry | 1998 |
|
Pharmacological expression in rat hepatocytes of a gene transferred by an adenovirus vector enabled by a chimeric promoter containing multiple cyclic adenosine monophosphate response elements
M Suzuki, RN Singh, RG Crystal |
Hepatology | 1998 |
|
Mice without myoglobin
DJ Garry, GA Ordway, JN Lorenz, NB Radford, ER Chin, RW Grange, R Bassel-Duby, RS Williams |
Nature | 1998 |
|
Utility and Importance of Gene Knockout Animals For Nutritional and Metabolic Research
DY Hui |
The Journal of nutrition | 1998 |
|
Reversal of Hypercholesterolemia in Apolipoprotein E2 and Apolipoprotein E3-Leiden Transgenic Mice by Adenovirus-Mediated Gene Transfer of the VLDL Receptor
KW van Dijk, BJ van Vlijmen, A van der Zee, B vant Hof, H van der Boom, K Kobayashi, L Chan, LM Havekes, MH Hofker |
Arteriosclerosis, thrombosis, and vascular biology | 1998 |
|
What’s New in Cardiovascular Imaging?
JH Reiber, EE Wall |
1998 | |
|
Induction of Early Atherosclerosis in LDL-Receptor–Deficient Mice Immunized With β 2 -Glycoprotein I
J George, A Afek, B Gilburd, M Blank, Y Levy, A Aron-Maor, H Levkovitz, A Shaish, I Goldberg, J Kopolovic, D Harats, Y Shoenfeld |
Circulation | 1998 |
|
Phenotype Interaction of apobec-1 and CETP , LDLR, and ApoE Gene Expression in Mice: Role of ApoB mRNA Editing in Lipoprotein Phenotype Expression
M Nakamuta, S Taniguchi, BY Ishida, K Kobayashi, L Chan |
Arteriosclerosis, thrombosis, and vascular biology | 1998 |
|
Unstable Coronary Artery Syndromes Pathophysiology, Diagnosis and Treatment
RL Wilensky |
1998 | |
|
Herz-Kreislauf-Erkrankungen
D Ganten, K Ruckpaul |
1998 | |
|
Molecular Biomethods Handbook
R Rapley, JM Walker |
1998 | |
|
Effect of probucol on LDL oxidation and atherosclerosis in LDL receptor-deficient mice
DA Bird, RK Tangirala, J Fruebis, D Steinberg, JL Witztum, W Palinski |
Journal of lipid research | 1998 |
|
Transport of maternal LDL and HDL to the fetal membranes and placenta of the Golden Syrian hamster is mediated by receptor-dependent and receptor-independent processes
KL Wyne, LA Woollett |
Journal of lipid research | 1998 |
|
Apolipoprotein E-deficient mice have impaired innate immune responses to Listeria monocytogenes in vivo
SE Roselaar, A Daugherty |
Journal of lipid research | 1998 |
|
Dual genetic pathways of endothelin-mediated intercellular signaling revealed by targeted disruption of endothelin converting enzyme-1 gene
H Yanagisawa, M Yanagisawa, RP Kapur, JA Richardson, SC Williams, DE Clouthier, D de Wit, N Emoto, RE Hammer |
Development (Cambridge, England) | 1998 |
|
Modification and Editing of RNA
H Grosjean, R Benne |
1998 | |
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Absence of P-selectin delays fatty streak formation in mice
RC Johnson, SM Chapman, ZM Dong, JM Ordovas, TN Mayadas, J Herz, RO Hynes, EJ Schaefer, DD Wagner |
Journal of Clinical Investigation | 1997 |
|
Reduced aortic lesions and elevated high density lipoprotein levels in transgenic mice overexpressing mouse apolipoprotein A-IV
RD Cohen, LW Castellani, JH Qiao, BJ van Lenten, AJ Lusis, K Reue |
Journal of Clinical Investigation | 1997 |
|
IFN-gamma potentiates atherosclerosis in ApoE knock-out mice
S Gupta, AM Pablo, X Jiang, N Wang, AR Tall, C Schindler |
Journal of Clinical Investigation | 1997 |
|
Paradoxical enhancement of atherosclerosis by probucol treatment in apolipoprotein E-deficient mice
SH Zhang, RL Reddick, E Avdievich, LK Surles, RG Jones, JB Reynolds, SH Quarfordt, N Maeda |
Journal of Clinical Investigation | 1997 |
|
Liver-directed gene transfer and prolonged expression of three major human ApoE isoforms in ApoE-deficient mice
K Tsukamoto, P Smith, JM Glick, DJ Rader |
Journal of Clinical Investigation | 1997 |
|
Susceptibility to atherosclerosis in mice expressing exclusively apolipoprotein B48 or apolipoprotein B100
MM Véniant, V Pierotti, D Newland, CM Cham, DA Sanan, RL Walzem, SG Young |
Journal of Clinical Investigation | 1997 |
|
The effects of total lymphocyte deficiency on the extent of atherosclerosis in apolipoprotein E-/- mice
A Daugherty, E Puré, D Delfel-Butteiger, S Chen, J Leferovich, SE Roselaar, DJ Rader |
Journal of Clinical Investigation | 1997 |
|
Lymphocytic airway infiltration as a precursor to fibrous obliteration in a rat model of bronchiolitis obliterans
L Boring, J Gosling, SW Chensue, SL Kunkel, RV Farese, HE Broxmeyer, IF Charo |
Journal of Clinical Investigation | 1997 |
|
Impaired secretion of very low density lipoprotein-triglycerides by apolipoprotein E- deficient mouse hepatocytes
F Kuipers, MC Jong, Y Lin, M Eck, R Havinga, V Bloks, HJ Verkade, MH Hofker, H Moshage, TJ Berkel, RJ Vonk, LM Havekes |
Journal of Clinical Investigation | 1997 |
|
Gene therapy for atherosclerosis
DJ Rader |
International Journal of Clinical & Laboratory Research | 1997 |
|
Adenovirus-Mediated Gene Transfer of Human Lipoprotein Lipase Ameliorates the Hyperlipidemias Associated with Apolipoprotein E and LDL Receptor Deficiencies in Mice
E Zsigmond, K Kobayashi, KW Tzung, L Li, Y Fuke, L Chan |
Human Gene Therapy | 1997 |
|
In VivoCorrection with Recombinant Adenovirus of 4-Hydroxyphenylpyruvic Acid Dioxygenase Deficiencies in StrainIIIMice
S Kubo, K Kiwaki, H Awata, H Katoh, Y Kanegae, I Saito, T Yamamoto, JI Miyazaki, I Matsuda, F Endo |
Human Gene Therapy | 1997 |
|
Apoptotic cell death in atherosclerotic plaques of hyperlipidemic knockout mice1Kenji Harada and Zhong Chen contributed equally to this work.1
K Harada, Z Chen, S Ishibashi, J Osuga, H Yagyu, K Ohashi, N Yahagi, F Shionoiri, L Sun, Y Yazaki, N Yamada |
Atherosclerosis | 1997 |
|
Stable in vivo gene transduction via a novel adenoviral/retroviral chimeric vector
M Feng, WH Jackson, CK Goldman, C Rancourt, M Wang, SK Dusing, G Siegal, DT Curiel |
Nature Biotechnology | 1997 |
|
Alcohol Feeding Impedes Early Atherosclerosis in Low-Density Lipoprotein Receptor Knockout Mice: Factors in Addition to High-Density Lipoprotein-Apolipoprotein A1 Are Involved
J Dai, BA Miller, RC Lin |
Alcoholism, clinical and experimental research | 1997 |
|
Reduction of serum cholesterol in Watanabe rabbits by xenogeneic hepatocellular transplantation
JR Gunsalus, DA Brady, SM Coulter, BM Gray, AS Edge |
Nature Medicine | 1997 |
|
Gene Therapy for Hepatic and Vascular Disorders
KP Ponder, JR Duncan, ME Hicks |
Journal of Vascular and Interventional Radiology | 1997 |
|
Cerebral lipid deposition in aged apolipoprotein-E-deficient mice
LC Walker, CA Parker, WJ Lipinski, MJ Callahan, RT Carroll, SE Gandy, JD Smith, M Jucker, CL Bisgaier |
The American Journal of Pathology | 1997 |
|
T and B lymphocytes play a minor role in atherosclerotic plaque formation in the apolipoprotein E-deficient mouse
HM Dansky, SA Charlton, MM Harper, JD Smith |
Proceedings of the National Academy of Sciences | 1997 |
|
A targeted mutation in the murine gene encoding the high density lipoprotein (HDL) receptor scavenger receptor class B type I reveals its key role in HDL metabolism
A Rigotti, BL Trigatti, M Penman, H Rayburn, J Herz, M Krieger |
Proceedings of the National Academy of Sciences | 1997 |
|
Gene therapy
MA Kay, D Liu, PM Hoogerbrugge |
Proceedings of the National Academy of Sciences | 1997 |
|
Receptor-targeted recombinant adenovirus conglomerates: a novel molecular conjugate vector with improved expression characteristics
P Schwarzenberger, JD Hunt, E Robert, C Theodossiou, JK Kolls |
Journal of virology | 1997 |
|
Expression of human cholesterol 7alpha-hydroxylase in atherosclerosis-susceptible mice via adenovirus infection
GL Moore, CA Drevon, D Machleder, JD Trawick, A McClelland, S Roy, R Lyons, R Jambou, RA Davis |
Biochemical Journal | 1997 |
|
Plasminogen deficiency accelerates vessel wall disease in mice predisposed to atherosclerosis
Q Xiao, MJ Danton, DP Witte, MC Kowala, MT Valentine, TH Bugge, JL Degen |
Proceedings of the National Academy of Sciences | 1997 |
|
Adenovirus-mediated suicide gene therapy for experimental bladder cancer
MA Sutton, SA Berkman, SH Chen, A Block, TD Dang, MW Kattan, TM Wheeler, DR Rowley, SL Woo, SP Lerner |
Urology | 1997 |
|
From the Academy: Gene therapy
MA Kay, D Liu, PM Hoogerbrugge |
Proceedings of the National Academy of Sciences | 1997 |
|
Overexpression of the HDL receptor SR-BI alters plasma HDL and bile cholesterol levels
KF Kozarsky, MH Donahee, A Rigotti, SN Iqbal, ER Edelman, M Krieger |
Nature | 1997 |
|
Antithrombotic gene therapy
RD Gerard |
Fibrinolysis and Proteolysis | 1997 |
|
Lymphocytic airway infiltration as a precursor to fibrous obliteration in a rat model of bronchiolitis obliterans
L Boring, J Gosling, SW Chensue, SL Kunkel, RV Farese, HE Broxmeyer, IF Charo |
Transplantation | 1997 |
|
The ER-overload response: activation of NF-kappa B
MA Hofmann, E Lalla, Y Lu, MR Gleason, BM Wolf, N Tanji, LJ Ferran, B Kohl, V Rao, W Kisiel, DM Stern, AM Schmidt |
Trends in Biochemical Sciences | 1997 |
|
Effects of apo E Deficiency on Plasma Lipid Levels in Mice Lacking APOBEC-1
J Osuga, H Yagyu, K Ohashi, K Harada, Y Yazaki, N Yamada, S Ishibashi |
Biochemical and Biophysical Research Communications | 1997 |
|
Adenovirus-mediated gene transfer of antisense ribozyme for α(1,3)galactosyltransferase gene and α(1,2)fucosyltransferase gene in xenotransplantation
S Hayashi, T Nagasaka, A Katayama, I Saito, H Hamada, T Kobayashi, I Yokoyama, S Ohtsuka, K Uchida, H Takagi |
Transplantation Proceedings | 1997 |
|
Effect of CTLA4-Ig gene transfer using adenoviral vector in organ and cell transplantation
S Hayashi, Y Namii, T Kozima, T Kobayashi, I Yokoyama, I Saito, H Hamada, S Ohtsuka, K Uchida, H Takagi |
Transplantation Proceedings | 1997 |
|
Adenovirus-mediated gene transfer to the xenogeneic liver in liver xenotransplantation: The transduction of complement regulatory factor genes (DAF and HRF20)
S Hayashi, C Koike, Y Namii, T Nagasaka, A Katayama, I Saito, H Okada, I Yokoyama, S Ohtsuka, K Uchida, H Takagi |
Transplantation Proceedings | 1997 |
|
Beta-amyloid protein-containing inclusions in skeletal muscle of apolipoprotein-E-deficient mice
TA Robertson, NS Dutton, RN Martins, AD Roses, BA Kakulas, JM Papadimitriou |
The American Journal of Pathology | 1997 |
|
Impact of Knockout Mice in Toxicology
B Ryffel |
Critical Reviews in Toxicology | 1997 |
|
Atherosclerosis in LDL-receptor knockout mice is accelerated by immunization with anticardiolipin antibodies
J George, A Afek, B Gilburd, Y Levy, M Blank, J Kopolovic, D Harats, Y Shoenfeld |
Lupus | 1997 |
|
Adenovirus gene therapy for hypercholesterolemia, thrombosis and restenosis
RD Gerard, D Collen |
Cardiovascular Research | 1997 |
|
INTRASPLENIC HEPATOCYTE ALLOTRANSPLANTATION IN DALMATIAN DOGS WITH AND WITHOUT CYCLOSPORINE IMMUNOSUPPRESSION1:
E Benedetti, JP Kirby, M Asolati, J Blanchard, MG Ward, R Williams, TA Hewett, M Fontaine, R Pollak |
Transplantation | 1997 |
|
Low-Density Lipoprotein Receptor Knockout Mice Exhibit Exaggerated Microvascular Responses to Inflammatory Stimuli
DD Henninger, ME Gerritsen, DN Granger |
Circulation research | 1997 |
|
Role of Leukocyte-Specific LDL Receptors on Plasma Lipoprotein Cholesterol and Atherosclerosis in Mice
WA Boisvert, J Spangenberg, LK Curtiss |
Arteriosclerosis, thrombosis, and vascular biology | 1997 |
|
Effective Lowering of Plasma, LDL, and Esterified Cholesterol in LDL Receptor–Knockout Mice by Adenovirus-Mediated Gene Delivery of ApoB mRNA Editing Enzyme (Apobec1)
BB Teng, B Ishida, TM Forte, S Blumenthal, LZ Song, AM Gotto, L Chan |
Arteriosclerosis, thrombosis, and vascular biology | 1997 |
|
Gene Transfer in the Cardiovascular System
KL March |
1997 | |
|
Genetic Factors Precipitating Type III Hyperlipoproteinemia in Hypolipidemic Transgenic Mice Expressing Human Apolipoprotein E2
Y Huang, SC Rall, RW Mahley |
Arteriosclerosis, thrombosis, and vascular biology | 1997 |
|
Liver LDL Receptor mRNA Expression Is Decreased in Human ApoB/CETP Double Transgenic Mice and Is Regulated by Diet as Well as the Cytokine Oncostatin M
J Liu, YL Zhang, MJ Spence, RE Vestal, PM Wallace, DS Grass |
Arteriosclerosis, thrombosis, and vascular biology | 1997 |
|
Effect of Bone Marrow Transplantation on Lipoprotein Metabolism and Atherosclerosis in LDL Receptor–Knockout Mice
N Herijgers, MV Eck, PH Groot, PM Hoogerbrugge, TJ Berkel |
Arteriosclerosis, thrombosis, and vascular biology | 1997 |
|
Effect of gene therapy with the herpes simplex virus-thymidine kinase gene on hepatic metastasis in murine colon cancer
S Hayashi, N Emi, I Yokoyama, K Uchida, H Takagi |
Surgery Today | 1997 |
|
Textbook of Coronary Thrombosis and Thrombolysis
RC Becker |
1997 | |
|
Adenovirus-Mediated Transfer of Tissue-Type Plasminogen Activator Augments Thrombolysis in Tissue-Type Plasminogen Activator–Deficient and Plasminogen Activator Inhibitor-1–Overexpressing Mice
P Carmeliet, JM Stassen, IV Vlaenderen, RS Meidell, D Collen, RD Gerard |
Blood | 1997 |
|
Automated measurement of mouse apolipoprotein B: convenient screening tool for mouse models of atherosclerosis
DM Levine, KJ Williams |
Clinical chemistry | 1997 |
|
Particle size determines the specificity of apolipoprotein E-containing triglyceride-rich emulsions for the LDL receptor versus hepatic remnant receptor in vivo
PC Rensen, N Herijgers, MH Netscher, SC Meskers, M van Eck, TJ van Berkel |
Journal of lipid research | 1997 |
|
Attenuation of plasma low density lipoprotein cholesterol by select 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors in mice devoid of low density lipoprotein receptors
CL Bisgaier, AD Essenburg, BJ Auerbach, ME Pape, CS Sekerke, A Gee, S Wölle, RS Newton |
Journal of lipid research | 1997 |
|
Cellular uptake of lipoprotein[a] by mouse embryonic fibroblasts via the LDL receptor and the LDL receptor-related protein
T Reblin, A Niemeier, N Meyer, TE Willnow, F Kronenberg, H Dieplinger, H Greten, U Beisiegel |
Journal of lipid research | 1997 |
|
Leukocyte low density lipoprotein receptor (LDL-R) does not contribute to LDL clearance in vivo: bone marrow transplantation studies in the mouse
S Fazio, AH Hasty, KJ Carter, AB Murray, JO Price, MF Linton |
Journal of lipid research | 1997 |
|
Hyperlipoproteinemia enhances susceptibility to acute disseminated Candida albicans infection in low-density-lipoprotein-receptor-deficient mice
MG Netea, PN Demacker, N de Bont, OC Boerman, AF Stalenhoef, JW van der Meer, BJ Kullberg |
Infection and immunity | 1997 |
|
Profound induction of hepatic cholesteryl ester transfer protein transgene expression in apolipoprotein E and low density lipoprotein receptor gene knockout mice. A novel mechanism signals changes in plasma cholesterol levels
L Masucci-Magoulas, A Plump, XC Jiang, A Walsh, JL Breslow, AR Tall |
Journal of Clinical Investigation | 1996 |
|
Hepatic lipase gene therapy in hepatic lipase-deficient mice. Adenovirus-mediated replacement of a lipolytic enzyme to the vascular endothelium
D Applebaum-Bowden, J Kobayashi, VS Kashyap, DR Brown, A Berard, S Meyn, C Parrott, N Maeda, R Shamburek, HB Brewer, S Santamarina-Fojo |
Journal of Clinical Investigation | 1996 |
|
Genes and physiology: molecular physiology in genetically engineered animals
KR Chien |
Journal of Clinical Investigation | 1996 |
|
Animal models of human disease for gene therapy
JM Wilson |
Journal of Clinical Investigation | 1996 |
|
Modulation of very low density lipoprotein production and clearance contributes to age- and gender- dependent hyperlipoproteinemia in apolipoprotein E3-Leiden transgenic mice
BJ van Vlijmen, HB van Hof, MJ Mol, H der Boom, A der Zee, RR Frants, MH Hofker, LM Havekes |
Journal of Clinical Investigation | 1996 |
|
Low-density lipoprotein receptor-deficient mice are protected against lethal endotoxemia and severe gram-negative infections
MG Netea, PN Demacker, BJ Kullberg, OC Boerman, I Verschueren, AF Stalenhoef, JW van der Meer |
Journal of Clinical Investigation | 1996 |
|
Apolipoprotein A-I is required for cholesteryl ester accumulation in steroidogenic cells and for normal adrenal steroid production
AS Plump, SK Erickson, W Weng, JS Partin, JL Breslow, DL Williams |
Journal of Clinical Investigation | 1996 |
|
Cloning of monoclonal autoantibodies to epitopes of oxidized lipoproteins from apolipoprotein E-deficient mice. Demonstration of epitopes of oxidized low density lipoprotein in human plasma
W Palinski, S Hörkkö, E Miller, UP Steinbrecher, HC Powell, LK Curtiss, JL Witztum |
Journal of Clinical Investigation | 1996 |
|
Regulation of scavenger receptor, class B, type I, a high density lipoprotein receptor, in liver and steroidogenic tissues of the rat
KT Landschulz, RK Pathak, A Rigotti, M Krieger, HH Hobbs |
Journal of Clinical Investigation | 1996 |
|
In the absence of the low density lipoprotein receptor, human apolipoprotein C1 overexpression in transgenic mice inhibits the hepatic uptake of very low density lipoproteins via a receptor-associated protein-sensitive pathway
MC Jong, VE Dahlmans, PJ van Gorp, KW van Dijk, ML Breuer, MH Hofker, LM Havekes |
Journal of Clinical Investigation | 1996 |
|
Adenovirus-Mediated Hepatic Gene Transfer in Mice: Comparison of Intravascular and Biliary Administration
MJ Peeters, GA Patijn, A Lieber, L Meuse, MA Kay |
Human Gene Therapy | 1996 |
|
Cardiovascular Gene Therapy: Current Concepts
JC Fox |
Therapeutic Drug Monitoring | 1996 |
|
Hepatic Expression of the Catalytic Subunit of the Apolipoprotein B mRNA Editing Enzyme (apobec-1) Ameliorates Hypercholesterolemia in LDL Receptor-Deficient Rabbits
KF Kozarsky, DK Bonen, F Giannoni, T Funahashi, JM Wilson, NO Davidson |
Human Gene Therapy | 1996 |
|
Gene therapy for metachromatic leukodystrophy
T Ohashi, K Watabe, Y Sato, I Saito, JA Barranger, R Matalon, Y Eto |
Pediatrics International | 1996 |
|
Correction of Ornithine Transcarbamylase Deficiency in AdultspfashMice and in OTC-Deficient Human Hepatocytes with Recombinant Adenoviruses Bearing the CAG Promoter
K Kiwaki, Y Kanegae, I Saito, S Komaki, K Nakamura, JI Miyazaki, F Endo, I Matsuda |
Human Gene Therapy | 1996 |
|
Mouse models of human genetic disease: Which mouse is more like a man?
RP Erickson |
BioEssays | 1996 |
|
Effective treatment of familial hypercholesterolaemia in the mouse model using adenovirus–mediated transfer of the VLDL receptor gene
KE Kozarsky, K Jooss, M Donahee, JF Strauss, JM Wilson |
Nature Genetics | 1996 |
|
High-Level Tissue-Specific Expression of Functional Human Factor VIII in Mice
S Connelly, JM Gardner, A McClelland, M Kaleko |
Human Gene Therapy | 1996 |
|
A 10-bp deletion in the apolipoprotein epsilon gene causing apolipoprotein E deficiency and severe type III hyperlipoproteinemia
G Feussner, J Dobmeyer, HJ Gröne, S Lohmer, S Wohlfeil |
The American Journal of Human Genetics | 1996 |
|
Remnant lipoproteins inhibit malaria sporozoite invasion of hepatocytes
P Sinnis, TE Willnow, MR Briones, J Herz, V Nussenzweig |
Journal of Experimental Medicine | 1996 |
|
Disappearance of body fat in normal rats induced by adenovirus-mediated leptin gene therapy
G Chen, K Koyama, X Yuan, Y Lee, YT Zhou, R O'Doherty, CB Newgard, RH Unger |
Proceedings of the National Academy of Sciences | 1996 |
|
Immunology of atherosclerosis: the promise of mouse models
AH Lichtman, M Cybulsky, FW Luscinskas |
The American Journal of Pathology | 1996 |
|
Centripetal cholesterol flux from extrahepatic organs to the liver is independent of the concentration of high density lipoprotein-cholesterol in plasma
Y Osono, LA Woollett, KR Marotti, GW Melchior, JM Dietschy |
Proceedings of the National Academy of Sciences | 1996 |
|
Suppression of diet-induced atherosclerosis in low density lipoprotein receptor knockout mice overexpressing lipoprotein lipase
M Shimada, S Ishibashi, T Inaba, H Yagyu, K Harada, JI Osuga, K Ohashi, Y Yazaki, N Yamada |
Proceedings of the National Academy of Sciences | 1996 |
|
Dramatically decreased high density lipoprotein cholesterol, increased remnant clearance, and insulin hypersensitivity in apolipoprotein A-II knockout mice suggest a complex role for apolipoprotein A-II in atherosclerosis susceptibility
W Weng, JL Breslow |
Proceedings of the National Academy of Sciences | 1996 |
|
Inhibition of atherosclerosis in CD4 T-cell-ablated and nude (nu/nu) C57BL/6 hyperlipidemic mice
EE Emeson, ML Shen, CG Bell, A Qureshi |
The American Journal of Pathology | 1996 |
|
The role of lipoprotein lipase and apoprotein E in the recognition of chylomicrons and chylomicron remnants by cultured isolated mouse hepatocytes
S Chang, N Maeda, J Borensztajn |
Biochemical Journal | 1996 |
|
Biology of adenovirus vectors with E1 and E4 deletions for liver-directed gene therapy
GP Gao, Y Yang, JM Wilson |
Journal of virology | 1996 |
|
Disruption of the acyl-CoA:cholesterol acyltransferase gene in mice: evidence suggesting multiple cholesterol esterification enzymes in mammals
VL Meiner, S Cases, HM Myers, ER Sande, S Bellosta, M Schambelan, RE Pitas, J McGuire, J Herz, RV Farese |
Proceedings of the National Academy of Sciences | 1996 |
|
Accelerated atheromatous lesions in mouse hearts transplanted to apolipoprotein-E-deficient recipients
PS Russell, CM Chase, RB Colvin |
The American Journal of Pathology | 1996 |
|
Urokinase-type plasminogen activator is effective in fibrin clearance in the absence of its receptor or tissue-type plasminogen activator
TH Bugge, MJ Flick, MJ Danton, CC Daugherty, J Romer, K Dano, P Carmeliet, D Collen, JL Degen |
Proceedings of the National Academy of Sciences | 1996 |
|
Chylomicron assembly and catabolism: role of apolipoproteins and receptors
MM Hussain, RK Kancha, Z Zhou, J Luchoomun, H Zu, A Bakillah |
Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism | 1996 |
|
Shear stress modulates expression of Cu/Zn superoxide dismutase in human aortic endothelial cells
T Fukai, ZS Galis, XP Meng, S Parthasarathy, DG Harrison |
Journal of Clinical Investigation | 1996 |
|
GENE THERAPY AND INHERITED DYSLIPIDEMIA
TO MD |
Endocrine Practice | 1996 |
|
Adenoviral delivery of low-density lipoprotein receptors to hyperlipidemic rabbits: Receptor expression modulates high-density lipoproteins
DR Brown, ME Brousseau, RD Shamburek, GD Talley, S Meyn, SJ Demosky, S Santamarina-Fojo, HB Brewer, JM Hoeg |
Metabolism | 1996 |
|
Novel neuritic clusters with accumulations of amyloid precursor protein and amyloid precursor-like protein 2 immunoreactivity in brain regions damaged by thiamine deficiency
NY Calingasan, SE Gandy, H Baker, KF Sheu, JD Smith, BT Lamb, JD Gearhart, JD Buxbaum, C Harper, DJ Selkoe, DL Price, SS Sisodia, GE Gibson |
The American Journal of Pathology | 1996 |
|
Disruption of cholesterol 7alpha-hydroxylase gene in mice. II. Bile acid deficiency is overcome by induction of oxysterol 7alpha-hydroxylase
M Schwarz, E G Lund, K D Setchell, H J Kayden, J E Zerwekh, I Björkhem, J Herz, D W Russell |
The Journal of biological chemistry | 1996 |
|
Disruption of Cholesterol 7α-Hydroxylase Gene in Mice
Margrit Schwarz, Erik G. Lund, Kenneth D. R. Setchell, Herbert J. Kayden, Joseph E. Zerwekh, Ingemar Björkhem, Joachim Herz, David W. Russell |
The Journal of biological chemistry | 1996 |
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Role of the Low Density Lipoprotein (LDL) Receptor Pathway in the Metabolism of Chylomicron Remnants: A QUANTITATIVE STUDY IN KNOCKOUT MICE LACKING THE LDL RECEPTOR, APOLIPOPROTEIN E, OR BOTH
S Ishibashi, S Perrey, Z Chen, J Osuga, M Shimada, K Ohashi, K Harada, Y Yazaki, N Yamada |
The Journal of biological chemistry | 1996 |
|
Reversal of Hypercholesterolemia in Low Density Lipoprotein Receptor Knockout Mice by Adenovirus-mediated Gene Transfer of the Very Low Density Lipoprotein Receptor
K Kobayashi, K Oka, T Forte, B Ishida, BB Teng, K Ishimura-Oka, M Nakamuta, L Chan |
The Journal of biological chemistry | 1996 |
|
Analysis of Protein Structure-Function in Vivo: ADENOVIRUS-MEDIATED TRANSFER OF LIPASE LID MUTANTS IN HEPATIC LIPASE-DEFICIENT MICE
J Kobayashi, D Applebaum-Bowden, KA Dugi, DR Brown, VS Kashyap, C Parrott, C Duarte, N Maeda, S Santamarina-Fojo |
The Journal of biological chemistry | 1996 |
|
Disruption of Cholesterol 7α-Hydroxylase Gene in Mice: II. BILE ACID DEFICIENCY IS OVERCOME BY INDUCTION OF OXYSTEROL 7α-HYDROXYLASE
M Schwarz, EG Lund, KD Setchell, HJ Kayden, JE Zerwekh, I Björkhem, J Herz, DW Russell |
The Journal of biological chemistry | 1996 |
|
Prolonged Metabolic Correction in Adult Ornithine Transcarbamylase-deficient Mice with Adenoviral Vectors
X Ye, MB Robinson, ML Batshaw, EE Furth, I Smith, JM Wilson |
The Journal of biological chemistry | 1996 |
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Differential Metabolic Effects of Adenovirus-mediated Glucokinase and Hexokinase I Overexpression in Rat Primary Hepatocytes
RM O'Doherty, DL Lehman, J Seoane, AM Gómez-Foix, JJ Guinovart, CB Newgard |
The Journal of biological chemistry | 1996 |
|
Lymphocyte Populations in Atherosclerotic Lesions of ApoE −/− and LDL Receptor −/− Mice: Decreasing Density With Disease Progression
SE Roselaar, PX Kakkanathu, A Daugherty |
Arteriosclerosis, thrombosis, and vascular biology | 1996 |
|
Adenovirus-Mediated Gene Transfer as an In Vivo Probe of Lipoprotein Metabolism
JM Leiden |
Circulation | 1996 |
|
Triggering of Acute Coronary Syndromes
SN Willich, JE Muller |
1996 | |
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Liver-directed gene transfer and application to therapy
V Sandig, M Strauss |
Journal of Molecular Medicine | 1996 |
|
Macrophage oxidative modification of low density lipoprotein occurs independently of its binding to the low density lipoprotein receptor
RK Tangirala, MJ Mol, D Steinberg |
Journal of lipid research | 1996 |
|
Isoproterenol decreases LDL receptor expression in rat adipose cells: activation of cyclic AMP-dependent proteolysis
FB Kraemer, V Natu, A Singh-Bist, S Patel, MC Komaromy, S Medicherla, S Azhar, C Sztalryd |
Journal of lipid research | 1996 |
|
Inhibition of diet-induced atheroma formation in transgenic mice expressing apolipoprotein E in the arterial wall
H Shimano, J Ohsuga, M Shimada, Y Namba, T Gotoda, K Harada, M Katsuki, Y Yazaki, N Yamada |
Journal of Clinical Investigation | 1995 |
|
In vivo gene therapy for hyperlipidemia: phenotypic correction in Watanabe rabbits by hepatic delivery of the rabbit LDL receptor gene
J Li, B Fang, RC Eisensmith, XH Li, I Nasonkin, YC Lin-Lee, MP Mims, A Hughes, CD Montgomery, JD Roberts |
Journal of Clinical Investigation | 1995 |
|
Role of the low density lipoprotein receptor in the flux of cholesterol through the plasma and across the tissues of the mouse
Y Osono, LA Woollett, J Herz, JM Dietschy |
Journal of Clinical Investigation | 1995 |
|
Transgenic mice expressing high levels of human apolipoprotein B develop severe atherosclerotic lesions in response to a high-fat diet
DA Purcell-Huynh, RV Farese, DF Johnson, LM Flynn, V Pierotti, DL Newland, MF Linton, DA Sanan, SG Young |
Journal of Clinical Investigation | 1995 |
|
Hepatic overexpression of bovine scavenger receptor type I in transgenic mice prevents diet-induced hyperbetalipoproteinemia
S Wölle, DP Via, L Chan, JA Cornicelli, CL Bisgaier |
Journal of Clinical Investigation | 1995 |
|
Treatment of severe hypercholesterolemia in apolipoprotein E-deficient mice by bone marrow transplantation
WA Boisvert, J Spangenberg, LK Curtiss |
Journal of Clinical Investigation | 1995 |
|
Adenovirus-mediated transfer of a gene encoding cholesterol 7 alpha-hydroxylase into hamsters increases hepatic enzyme activity and reduces plasma total and low density lipoprotein cholesterol
DK Spady, JA Cuthbert, MN Willard, RS Meidell |
Journal of Clinical Investigation | 1995 |
|
Apolipoprotein E deficiency in mice: gene replacement and prevention of atherosclerosis using adenovirus vectors
VS Kashyap, S Santamarina-Fojo, DR Brown, CL Parrott, D Applebaum-Bowden, S Meyn, G Talley, B Paigen, N Maeda, HB Brewer |
Journal of Clinical Investigation | 1995 |
|
Atherogenesis in transgenic mice with human apolipoprotein B and lipoprotein (a)
MJ Callow, J Verstuyft, R Tangirala, W Palinski, EM Rubin |
Journal of Clinical Investigation | 1995 |
|
Decreased early atherosclerotic lesions in hypertriglyceridemic mice expressing cholesteryl ester transfer protein transgene
T Hayek, L Masucci-Magoulas, X Jiang, A Walsh, E Rubin, JL Breslow, AR Tall |
Journal of Clinical Investigation | 1995 |
|
apo B gene knockout in mice results in embryonic lethality in homozygotes and neural tube defects, male infertility, and reduced HDL cholesterol ester and apo A-I transport rates in heterozygotes
LS Huang, E Voyiaziakis, DF Markenson, KA Sokol, T Hayek, JL Breslow |
Journal of Clinical Investigation | 1995 |
|
Gene therapy for metabolic disorders
N Bowles, SL Woo |
Advanced Drug Delivery Reviews | 1995 |
|
A pilot study of ex vivo gene therapy for homozygous familial hypercholesterolaemia
M Grossman, DJ Rader, DW Muller, DM Kolansky, K Kozarsky, BJ Clark, EA Stein, PJ Lupien, HB Brewer, SE Raper, JM Wilson |
Nature Medicine | 1995 |
|
Potential gene therapy strategies in the treatment of cardiovascular disease
RT Rowland, JC Cleveland, X Meng, AH Harken, JM Brown |
The Annals of Thoracic Surgery | 1995 |
|
FK506 Immunosuppression to Control the Immune Reactions Triggered by First-Generation Adenovirus-Mediated Gene Transfer
JT Vilquin, B Guérette, I Kinoshita, B Roy, M Goulet, C Gravel, R Roy, JP Tremblay |
Human Gene Therapy | 1995 |
|
Gene transfer and disruption strategies to elucidate hepatic lipoprotein receptor functions
J Herz, TE Willnow |
Atherosclerosis | 1995 |
|
Gene therapy for the vulnerable plaque
LJ Feldman, JM Isner |
Journal of the American College of Cardiology | 1995 |
|
Long–term hepatic adenovirus–mediated gene expression in mice following CTLA4Ig administration
MA Kay, AX Holterman, L Meuse, A Gown, HD Ochs, PS Linsley, CB Wilson |
Nature Genetics | 1995 |
|
Lesch-Nyhan disease as a model for central nervous system directed gene therapy
T Friedmann |
Mental Retardation and Developmental Disabilities Research Reviews | 1995 |
|
Prospects for gene therapy in ornithine carbamoyltransferase deficiency and other urea cycle disorders
MB Robinson, ML Batshaw, X Ye, JM Wilson |
Mental Retardation and Developmental Disabilities Research Reviews | 1995 |
|
Targeting the mouse genome: a compendium of knockouts (part II)
EP Brandon, RL Idzerda, GS McKnight |
Current Biology | 1995 |
|
Recombinant IL–12 prevents formation of blocking IgA antibodies to recombinant adenovirus and allows repeated gene therapy to mouse lung
Y Yang, G Trinchieri, JM Wilson |
Nature Medicine | 1995 |
|
The use of adenoviral vectors for gene therapy and gene transfer in vivo
JL Bramson, FL Graham, J Gauldie |
Current Opinion in Biotechnology | 1995 |
|
Initial hepatic removal of chylomicron remnants is unaffected but endocytosis is delayed in mice lacking the low density lipoprotein receptor
J Herz, SQ Qiu, A Oesterle, HV DeSilva, S Shafi, RJ Havel |
Proceedings of the National Academy of Sciences | 1995 |
|
Inhibition of diet-induced atheroma formation in transgenic mice expressing apolipoprotein E in the arterial wall
H Shimano, J Ohsuga, M Shimada, Y Namba, T Gotoda, K Harada, M Katsuki, Y Yazaki, N Yamada |
Science | 1995 |
|
Mice deficient in cystathionine beta-synthase: animal models for mild and severe homocyst(e)inemia
M Watanabe, J Osada, Y Aratani, K Kluckman, R Reddick, MR Malinow, N Maeda |
Proceedings of the National Academy of Sciences | 1995 |
|
Suppression of erythro-megakaryocytopoiesis and the induction of reversible thrombocytopenia in mice transgenic for the thymidine kinase gene targeted by the platelet glycoprotein alpha IIb promoter
DT Roux, V Roullot, A Schweitzer, R Berthier, G Marguerie |
Journal of Experimental Medicine | 1995 |
|
Beta-migrating very-low-density lipoproteins and chylomicron remnants bind to rat liver hepatocytes at a low-density-lipoprotein-receptor-independent site (the remnant receptor)
JC van Berkel, A Voorschuur, J Kuiper |
Biochemical Journal | 1995 |
|
Increased response to cholesterol feeding in apolipoprotein C1-deficient mice
JH van Ree, MH Hofker, WJ van Broek, JM van Deursen, H der Boom, RR Frants, B Wieringa, LM Havekes |
Biochemical Journal | 1995 |
|
Cellular and humoral immune responses to adenoviral vectors containing factor IX gene: tolerization of factor IX and vector antigens allows for long-term expression
Y Dai, EM Schwarz, D Gu, WW Zhang, N Sarvetnick, IM Verma |
Proceedings of the National Academy of Sciences | 1995 |
|
Gene targeting approaches to complex genetic diseases: atherosclerosis and essential hypertension
O Smithies, N Maeda |
Proceedings of the National Academy of Sciences | 1995 |
|
The role of immunosuppression in the efficacy of cancer gene therapy using adenovirus transfer of the herpes simplex thymidine kinase gene
AA Elshami, JC Kucharczuk, DH Sterman, WR Smythe, HC Hwang, KM Amin, LA Litzky, SM Albelda, LR Kaiser |
Annals of Surgery | 1995 |
|
Functional expression of low density lipoprotein receptor-related protein is controlled by receptor-associated protein in vivo
TE Willnow, SA Armstrong, RE Hammer, J Herz |
Proceedings of the National Academy of Sciences | 1995 |
|
Scavenger receptor A gene regulatory elements target gene expression to macrophages and to foam cells of atherosclerotic lesions
A Horvai, W Palinski, H Wu, KS Moulton, K Kalla, CK Glass |
Proceedings of the National Academy of Sciences | 1995 |
|
Cytochrome P450 1A1 promoter as a genetic switch for the regulatable and physiological expression of a plasma protein in transgenic mice
JD Smith, E Wong, M Ginsberg |
Proceedings of the National Academy of Sciences | 1995 |
|
Decreased atherosclerosis in mice deficient in both macrophage colony-stimulating factor (op) and apolipoprotein E
JD Smith, E Trogan, M Ginsberg, C Grigaux, J Tian, M Miyata |
Proceedings of the National Academy of Sciences | 1995 |
|
Biotechnology Annual Review
S Hashida, K Hashinaka, E Ishikawa |
Biotechnology Annual Review | 1995 |
|
Genetic Manipulation of the Nervous System
M Heilig, KH Schlingensiepen |
Genetic Manipulation of the Nervous System | 1995 |
|
Mild dyslipidemia in mice following targeted inactivation of the hepatic lipase gene
PK Frykman, MS Brown, T Yamamoto, JL Goldstein, J Herz |
The Journal of biological chemistry | 1995 |
|
Liver-directed gene therapy: molecular tools and current preclinical and clinical studies
M Alt, WH Caselmann |
Journal of Hepatology | 1995 |
|
Section Review: Cardiovascular & Renal: Genetic therapies for vascular diseases and lipid disorders
P Denèfle, N Duverger, D Branellec |
Expert Opinion on Investigational Drugs | 1995 |
|
Gene therapy of hypercholesterolemic disorders
KF Kozarsky, JM Wilson |
Trends in Cardiovascular Medicine | 1995 |
|
Salt-resistant hypertension in mice lacking the guanylyl cyclase-A receptor for atrial natriuretic peptide
MJ Lopez, SK Wong, I Kishimoto, S Dubois, V Mach, J Friesen, DL Garbers, A Beuve |
Nature | 1995 |
|
Overexpression of Human Lipoprotein Lipase Protects Diabetic Transgenic Mice From Diabetic Hypertriglyceridemia and Hypercholesterolemia
M Shimada, S Ishibashi, T Gotoda, M Kawamura, K Yamamoto, T Inaba, K Harada, J Ohsuga, S Perrey, Y Yazaki, N Yamada |
Arteriosclerosis, thrombosis, and vascular biology | 1995 |
|
Effect of the Antioxidant N,N′ -Diphenyl 1,4-Phenylenediamine (DPPD) on Atherosclerosis in ApoE-Deficient Mice
RK Tangirala, F Casanada, E Miller, JL Witztum, D Steinberg, W Palinski |
Arteriosclerosis, thrombosis, and vascular biology | 1995 |
|
Estrogen-Induced Alterations in Lipoprotein Metabolism in Autoimmune MRL/lpr Mice
SH Zuckerman, N Bryan-Poole |
Arteriosclerosis, thrombosis, and vascular biology | 1995 |
|
Increased Autoantibody Titers Against Epitopes of Oxidized LDL in LDL Receptor–Deficient Mice With Increased Atherosclerosis
W Palinski, RK Tangirala, E Miller, SG Young, JL Witztum |
Arteriosclerosis, thrombosis, and vascular biology | 1995 |
|
Genetic Models of Human Vascular Disease
VJ Dzau, GH Gibbons, BK Kobilka, RM Lawn, RE Pratt |
Circulation | 1995 |
|
Phenotypic Correction of Hypercholesterolemia in ApoE-Deficient Mice by Adenovirus-Mediated In Vivo Gene Transfer
SC Stevenson, J Marshall-Neff, B Teng, CB Lee, S Roy, A McClelland |
Arteriosclerosis, thrombosis, and vascular biology | 1995 |
|
Relative Contributions of Apolipoprotein(a) and Apolipoprotein-B to the Development of Fatty Lesions in the Proximal Aorta of Mice
FP Mancini, DL Newland, V Mooser, J Murata, S Marcovina, SG Young, RE Hammer, DA Sanan, HH Hobbs |
Arteriosclerosis, thrombosis, and vascular biology | 1995 |
|
Molekularbiologische Grundlagen der Gastroenterologie
HG Beger, MP Manns, H Greten |
1995 | |
|
Cardiovascular Disease 2
LL Gallo |
1995 | |
|
Nutrition and Biotechnology in Heart Disease and Cancer
JB Longenecker, D Kritchevsky, MK Drezner |
1995 | |
|
The Molecular Repertoire of Adenoviruses I
W Doerfler, P Böhm |
1995 | |
|
Quantitation of atherosclerosis in murine models: correlation between lesions in the aortic origin and in the entire aorta, and differences in the extent of lesions between sexes in LDL receptor-deficient and apolipoprotein E-deficient mice
RK Tangirala, EM Rubin, W Palinski |
Journal of lipid research | 1995 |
|
Expression of mouse alpha-macroglobulins, lipoprotein receptor-related protein, LDL receptor, apolipoprotein E, and lipoprotein lipase in pregnancy
L Overbergh, K Lorent, S Torrekens, FV Leuven, HV den Berghe |
Journal of lipid research | 1995 |
|
Transgenic mice expressing both human apolipoprotein B and human CETP have a lipoprotein cholesterol distribution similar to that of normolipidemic humans
DS Grass, U Saini, RH Felkner, RE Wallace, WJ Lago, SG Young, ME Swanson |
Journal of lipid research | 1995 |
|
Structure of the murine macrophage scavenger receptor gene and evaluation of sequences that regulate expression in the macrophage cell line, P388D
RP Aftring, MW Freeman |
Journal of lipid research | 1995 |
|
Animal models for disorders of hepatic lipoprotein metabolism
TE Willnow, J Herz |
Journal of Molecular Medicine | 1995 |
|
Gene therapy. Clinical potential and relationship to drug treatment.
Whartenby KA, Marrogi AJ, Freeman SM |
Drugs | 1995 |
|
Diet-induced hyperlipoproteinemia and atherosclerosis in apolipoprotein E3-Leiden transgenic mice
BJ van Vlijmen, AM van Maagdenberg, MJ Gijbels, H der Boom, H HogenEsch, RR Frants, MH Hofker, LM Havekes |
Journal of Clinical Investigation | 1994 |
|
Intestinal expression of human apolipoprotein A-IV in transgenic mice fails to influence dietary lipid absorption or feeding behavior
K Aalto-Setälä, CL Bisgaier, A Ho, KA Kieft, MG Traber, HJ Kayden, R Ramakrishnan, A Walsh, AD Essenburg, JL Breslow |
Journal of Clinical Investigation | 1994 |
|
Apolipoprotein AI transgene corrects apolipoprotein E deficiency-induced atherosclerosis in mice
C Pászty, N Maeda, J Verstuyft, EM Rubin |
Journal of Clinical Investigation | 1994 |
|
Diet-induced atherosclerosis in mice heterozygous and homozygous for apolipoprotein E gene disruption
SH Zhang, RL Reddick, B Burkey, N Maeda |
Journal of Clinical Investigation | 1994 |
|
Gene therapy for cholesterol
MS Brown, JL Goldstein, RJ Havel, D Steinberg |
Nature Genetics | 1994 |
|
Recent concepts of lipoprotein pathophysiology
G Schonfeld |
Atherosclerosis | 1994 |
|
More to learn from gene knockouts
BS Shastry |
Molecular and Cellular Biochemistry | 1994 |
|
Mouse Very-Low-Density-Lipoprotein Receptor (VLDLR) cDNA Cloning, Tissue-specific Expression and Evolutionary Relationship with the Low-density-lipoprotein Receptor
K Oka, K Ishimura-Oka, M Chu, M Sullivan, J Krushkal, WH Li, L Chan |
European Journal of Biochemistry | 1994 |
|
Atherosclerosis in mice: getting to the heart of a polygenic disorder
EM Rubin, DJ Smith |
Trends in Genetics | 1994 |
|
Gene therapy using adenoviral vectors
BC Trapnell, M Gorziglia |
Current Opinion in Biotechnology | 1994 |
|
Antisense oligonucleotide strategies in physiology
AJ Baertschi |
Molecular and Cellular Endocrinology | 1994 |
|
Potential Roles for the Low Density Lipoprotein Receptor Family of Proteins in Implantation and Placentation
G Coukos, ME Gåfvels, F Wittmaack, H Matsuo, DK Strickland, C Coutifaris, JF Strauss |
Annals of the New York Academy of Sciences | 1994 |
|
Functions of the LDL Receptor Gene Family
J Herz, TE Willnow |
Annals of the New York Academy of Sciences | 1994 |
|
Targeted and natural (piebald-lethal) mutations of endothelin-B receptor gene produce megacolon associated with spotted coat color in mice
K Hosoda, RE Hammer, JA Richardson, AG Baynash, JC Cheung, A Giaid, M Yanagisawa |
Cell | 1994 |
|
Gene therapy for phenylketonuria
RC Eisensmith, SL Woo |
Acta Paediatrica | 1994 |
|
A plasma lipoprotein containing only apolipoprotein E and with gamma mobility on electrophoresis releases cholesterol from cells
Y Huang, A Eckardstein, S Wu, N Maeda, G Assmann |
Proceedings of the National Academy of Sciences | 1994 |
|
Apolipoprotein E localization in human coronary atherosclerotic plaques by in situ hybridization and immunohistochemistry and comparison with lipoprotein lipase
KD O'Brien, SS Deeb, M Ferguson, TO McDonald, MD Allen, CE Alpers, A Chait |
The American Journal of Pathology | 1994 |
|
The two-receptor model of lipoprotein clearance: tests of the hypothesis in "knockout" mice lacking the low density lipoprotein receptor, apolipoprotein E, or both proteins
S Ishibashi, J Herz, N Maeda, JL Goldstein, MS Brown |
Proceedings of the National Academy of Sciences | 1994 |
|
Human apolipoprotein A-I gene expression increases high density lipoprotein and suppresses atherosclerosis in the apolipoprotein E-deficient mouse
AS Plump, CJ Scott, JL Breslow |
Proceedings of the National Academy of Sciences | 1994 |
|
Cellular immunity to viral antigens limits E1-deleted adenoviruses for gene therapy
Y Yang, FA Nunes, K Berencsi, EE Furth, E Gönczöl, JM Wilson |
Proceedings of the National Academy of Sciences | 1994 |
|
Advances in Pharmacology
B Drenger, Y Ginosar, Y Gozal |
Advances in Pharmacology | 1994 |
|
Use of recombinant adenovirus for metabolic engineering of mammalian cells
EV Schaftingen, B Lederer, R Bartrons, HG Hers |
Methods in cell biology | 1994 |
|
Interaction of endothelin-3 with endothelin-B receptor is essential for development of epidermal melanocytes and enteric neurons
AG Baynash, K Hosoda, A Giaid, JA Richardson, N Emoto, RE Hammer, M Yanagisawa |
Cell | 1994 |
|
Gene Therapy for Metabolic Diseases
MA Kay, SL Woo |
ILAR journal / National Research Council, Institute of Laboratory Animal Resources | 1994 |
|
Coronary atherosclerosis in transplanted mouse hearts. I. Time course and immunogenetic and immunopathological considerations
PS Russell, CM Chase, HJ Winn, RB Colvin |
The American Journal of Pathology | 1994 |
|
Southwestern Internal Medicine Conference: Endothelial Dysfunction and Vascular Disease
RS Meidell |
The American Journal of the Medical Sciences | 1994 |
|
ApoE-deficient mice are a model of lipoprotein oxidation in atherogenesis. Demonstration of oxidation-specific epitopes in lesions and high titers of autoantibodies to malondialdehyde-lysine in serum
W Palinski, VA Ord, AS Plump, JL Breslow, D Steinberg, JL Witztum |
Arteriosclerosis Thrombosis and Vascular Biology | 1994 |
|
Pathology of atheromatous lesions in inbred and genetically engineered mice. Genetic determination of arterial calcification
JH Qiao, PZ Xie, MC Fishbein, J Kreuzer, TA Drake, LL Demer, AJ Lusis |
Arteriosclerosis Thrombosis and Vascular Biology | 1994 |
|
Hepatic Encephalopathy, Hyperammonemia, and Ammonia Toxicity
V Felipo, S Grisolia |
1994 | |
|
Inhibition of Hepatic Chylomicron Remnant Uptake by Gene Transfer of a Receptor Antagonist
TE Willnow, Z Sheng, S Ishibashi, J Herz |
Science | 1994 |
|
Effect of the 39-kDa receptor-associated protein on the hepatic uptake and endocytosis of chylomicron remnants and low density lipoproteins in the rat
H Mokuno, S Brady, L Kotite, J Herz, RJ Havel |
The Journal of biological chemistry | 1994 |
|
Low density lipoprotein receptors in rat adipose cells: subcellular localization and regulation by insulin
FB Kraemer, SA Sather, B Park, C Sztalryd, V Natu, K May, H Nishimura, I Simpson, AD Cooper, SW Cushman |
Journal of lipid research | 1994 |
|
Asialoglycoprotein receptor deficiency in mice lacking the minor receptor subunit
S Ishibashi, RE Hammer, J Herz |
The Journal of biological chemistry | 1994 |
|
Adenovirus-mediated gene transfer of rat apolipoprotein B mRNA-editing protein in mice virtually eliminates apolipoprotein B-100 and normal low density lipoprotein production
B Teng, S Blumenthal, T Forte, N Navaratnam, J Scott, AM Gotto, L Chan |
The Journal of biological chemistry | 1994 |
|
In vivo correction of low density lipoprotein receptor deficiency in the Watanabe heritable hyperlipidemic rabbit with recombinant adenoviruses
KF Kozarsky, DR McKinley, LL Austin, SE Raper, LD Stratford-Perricaudet, JM Wilson |
The Journal of biological chemistry | 1994 |
|
Expression of a thyroid hormone-responsive recombinant gene introduced into adult mice livers by replication-defective adenovirus can be regulated by endogenous thyroid hormone receptor
Y Hayashi, AM DePaoli, CF Burant, S Refetoff |
The Journal of biological chemistry | 1994 |
|
Murine models for study of lipoprotein metabolism and atherosclerosis
JL Witztum |
Journal of Clinical Investigation | 1993 |
|
Type III hyperlipoproteinemic phenotype in transgenic mice expressing dysfunctional apolipoprotein E
S Fazio, YL Lee, ZS Ji, SC Rall |
Journal of Clinical Investigation | 1993 |
|
Transgenic mice expressing high plasma concentrations of human apolipoprotein B100 and lipoprotein(a)
MF Linton, RV Farese, G Chiesa, DS Grass, P Chin, RE Hammer, HH Hobbs, SG Young |
Journal of Clinical Investigation | 1993 |
|
Targeted modification of the apolipoprotein B gene results in hypobetalipoproteinemia and developmental abnormalities in mice
GE Homanics, TJ Smith, SH Zhang, D Lee, SG Young, N Maeda |
Proceedings of the National Academy of Sciences | 1993 |
|
Transgenic mouse models of lipoprotein metabolism and atherosclerosis
JL Breslow |
Proceedings of the National Academy of Sciences | 1993 |
|
Lipoprotein-cholesterol levels in infertile women with luteal phase deficiency
Y Terasawa, Z Ladha, SW Leonard, JD Morrow, D Newland, D Sanan, L Packer, MG Traber, RV Farese |
Fertility and Sterility | 1991 |
|
A polymorphism affecting apolipoprotein A-II translational efficiency determines high density lipoprotein size and composition
S Ishibashi, JL Goldstein, MS Brown, J Herz, DK Burns |
Journal of Clinical Investigation | 1990 |
|
Animal models of atherosclerosis
ML Armstrong, DD Heistad |
Atherosclerosis | 1990 |
|
A polymorphism affecting apolipoprotein A-II translational efficiency determines high density lipoprotein size and composition
S Ishibashi, JL Goldstein, MS Brown, J Herz, DK Burns |
Journal of Clinical Investigation | 1990 |
|
Vitamin D
A Portale, Β Halloran, E Lonergan, R Morris |
Vitamin D | 1988 |
|
Advances in Genetics
BH Bowman, F Yang, GS Adrian |
Advances in genetics | 1988 |
|
The amino-terminal hydrophobic region of the small subunit of calcium-activated neutral protease (CANP) is essential for its activation by phosphatidylinositol
S Bellosta, RW Mahley, DA Sanan, J Murata, DL Newland, JM Taylor, RE Pitas |
Journal of Clinical Investigation | 1986 |
|
The amino-terminal hydrophobic region of the small subunit of calcium-activated neutral protease (CANP) is essential for its activation by phosphatidylinositol
S Bellosta, RW Mahley, DA Sanan, J Murata, DL Newland, JM Taylor, RE Pitas |
Journal of Clinical Investigation | 1986 |
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