Cells within the synovial tissue may recruit mononuclear phagocytes into the synovial fluid and tissues of arthritic patients. We investigated the production of the chemotactic cytokine monocyte chemoattractant protein-1 (MCP-1) using sera, synovial fluid, synovial tissue, as well as macrophages and fibroblasts isolated from synovial tissues from 80 arthritic patients. MCP-1 levels were significantly higher (P less than 0.05) in synovial fluid from RA patients (mean 25.5 +/- 8.1 ng/ml [SE]) compared to synovial fluid from osteoarthritis (OA) patients (0.92 +/- 0.08), or from patients with other arthritides (2.9 +/- 1.5). MCP-1 levels in RA sera (8.44 +/- 2.33) were significantly greater than MCP-1 in normal sera (0.16 +/- 0.06). The quantities of RA synovial fluid IL-8, which is chemotactic for neutrophils and lymphocytes, and MCP-1 were strongly positively correlated (P less than 0.05). To examine the cellular source of MCP-1, RA synovial tissue macrophages and fibroblasts were isolated. Synovial tissue fibroblasts did not express MCP-1 mRNA, but could be induced to produce MCP-1 by stimulation with either IL-1 beta, tumor necrosis factor-alpha (TNF-alpha), or LPS. In contrast, unlike normal peripheral blood monocytes or alveolar macrophages, RA synovial tissue macrophages constitutively expressed MCP-1 mRNA and antigen. Immunohistochemical analysis of synovial tissue showed that a significantly greater percentage of RA macrophages (50 +/- 8%) as compared to either OA macrophages (5 +/- 2) or normal macrophages (1 +/- 0.3) reacted with anti-MCP-1 antibodies. In addition, the synovial lining layer reacted with MCP-1 in both RA and OA synovial tissues. In contrast, only a minority of synovial fibroblasts (18 +/- 8%) from RA synovium were positive for immunolocalization of MCP-1. These results suggest that synovial production of MCP-1 may play an important role in the recruitment of mononuclear phagocytes during inflammation associated with RA and that synovial tissue macrophages are the dominant source of this cytokine.
A E Koch, S L Kunkel, L A Harlow, B Johnson, H L Evanoff, G K Haines, M D Burdick, R M Pope, R M Strieter
Title and authors | Publication | Year |
---|---|---|
Investigating the Role of Gut Microbiota in the Pathogenesis and Progression of Rheumatoid Arthritis in a Collagen-Induced Arthritis Mouse Model
Belvončíková P, Macáková K, Tóthová N, Babál P, Tarabčáková L, Gardlík R |
International Journal of Molecular Sciences | 2025 |
Therapeutic potential of a rhein-loaded self-nano-emulsifying drug delivery system in ameliorating LPS-induced depression: mechanistic insights and behavioral outcomes
More S, Rashid MA, Tiwari PK, Kharwade R, Alhamhoom Y, Asar TO, Kaleem M, Mahajan N, Pise A, Danao K, Kumar S |
Frontiers in Pharmacology | 2025 |
Targeting proprotein convertase subtilisin/kexin type 9 (PCSK9): from bench to bedside.
Bao X, Liang Y, Chang H, Cai T, Feng B, Gordon K, Zhu Y, Shi H, He Y, Xie L |
Signal Transduction and Targeted Therapy | 2024 |
IGF-1 Genome-Edited Human MSCs Exhibit Robust Anti-Arthritogenicity in Collagen-Induced Arthritis
Chae DS, Han S, Kim SW |
International journal of molecular sciences | 2024 |
The chromatin landscape of pathogenic transcriptional cell states in rheumatoid arthritis
Weinand K, Sakaue S, Nathan A, Jonsson AH, Zhang F, Watts GF, Al Suqri M, Zhu Z, Rao DA, Anolik JH, Brenner MB, Donlin LT, Wei K, Raychaudhuri S |
Nature Communications | 2024 |
Targeting PAR2-mediated inflammation in osteoarthritis: a comprehensive in vitro evaluation of oleocanthal’s potential as a functional food intervention for chondrocyte protection and anti-inflammatory effects
Patnaik R, Varghese R, Jannati S, Naidoo N, Banerjee Y |
BMC Musculoskeletal Disorders | 2024 |
Systematic perturbation screens identify regulators of inflammatory macrophage states and a role for TNF mRNA m6A modification.
Haag SM, Xie S, Eidenschenk C, Fortin JP, Callow M, Costa M, Lun A, Cox C, Wu SZ, Pradhan RN, Lock J, Kuhn JA, Holokai L, Thai M, Freund E, Nissenbaum A, Keir M, Bohlen CJ, Martin S, Geiger-Schuller K, Hejase HA, Yaspan BL, Melo Carlos S, Turley SJ, Murthy A |
Nature genetics | 2024 |
Mammalian Glycosylation Patterns Protect Citrullinated Chemokine MCP-1/CCL2 from Partial Degradation.
Korchynskyi O, Yoshida K, Korchynska N, Czarnik-Kwaśniak J, Tak PP, Pruijn GJM, Isozaki T, Ruth JH, Campbell PL, Amin MA, Koch AE |
International journal of molecular sciences | 2023 |
Synergism between chikungunya virus infection and rheumatoid arthritis on cytokine levels: Clinical implications?
Bezerra LA, da Silva Bastos YC, Gonçales JP, Silva Júnior JVJ, de Lorena VMB, Duarte ALBP, Marques CDL, Coêlho MRCD |
Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] | 2023 |
Role of high-temperature requirement serine protease A 2 in rheumatoid inflammation.
Jeong GH, Nam MK, Hur W, Heo S, Lee S, Choi E, Park JH, Park Y, Kim WU, Rhim H, Yoo SA |
Arthritis Research & Therapy | 2023 |
Sialic-Acid-Related Enzymes of B Cells and Monocytes as Novel Markers to Discriminate Improvement Categories and to Fulfill Two Remission Definitions in Rheumatoid Arthritis.
Liou LB, Tsai PH, Fang YF, Chen YF, Chen CC, Lai JH |
International journal of molecular sciences | 2023 |
Activities and Molecular Mechanisms of Diterpenes, Diterpenoids, and Their Derivatives in Rheumatoid Arthritis.
Torequl Islam M, Quispe C, Herrera-Bravo J, Rahaman MM, Hossain R, Sarkar C, Raihan MA, Chowdhury MM, Uddin SJ, Shilpi JA, Marcelo de Castro E Sousa J, Melo-Cavalcante AAC, Mubarak MS, Sharifi-Rad J, Calina D |
Evidence-based complementary and alternative medicine : eCAM | 2022 |
Anti-Arthritogenic Property of Interleukin 10-Expressing Human Amniotic MSCs Generated by Gene Editing in Collagen-Induced Arthritis.
Chae DS, Park YJ, Kim SW |
International journal of molecular sciences | 2022 |
CS12192, a Novel JAK3/JAK1/TBK1 Inhibitor, Synergistically Enhances the Anti-Inflammation Effect of Methotrexate in a Rat Model of Rheumatoid Arthritis.
Fang Z, Hu Y, Dai J, He L, He J, Xu B, Han X, Zhong F, Lan H, Wang Q |
International journal of molecular sciences | 2022 |
C-C motif chemokine ligand 2 promotes myogenesis of myoblasts via the AKT-mTOR pathway
Kwak MK, Ha ES, Lee J, Choi YM, Kim BJ, Hong EG |
Aging | 2022 |
Enhanced Anti-Inflammatory Effect of the Combination of Lactiplantibacillus plantarum LS/07 with Methotrexate Compared to Their Monotherapies Studied in Experimental Arthritis.
Pružinská K, Slovák L, Dráfi F, Poništ S, Juránek I, Chrastina M, Švík K, Strojný L, Ambro Ľ, Bauerová K |
Molecules (Basel, Switzerland) | 2022 |
A myostatin-CCL20–CCR6 axis regulates Th17 cell recruitment to inflamed joints in experimental arthritis
M Fennen, T Weinhage, V Kracke, J Intemann, G Varga, C Wehmeyer, D Foell, A Korb-Pap, T Pap, B Dankbar |
Scientific Reports | 2021 |
Tumor Microenvironment: The Role of Chemokines – Part B
A Birbrair |
2021 | |
Tumor Microenvironment: The Role of Chemokines – Part B
A Birbrair |
2021 | |
Tumor Microenvironment: The Role of Chemokines – Part B
A Birbrair |
2021 | |
Tumor Microenvironment: The Role of Chemokines – Part B
A Birbrair |
2021 | |
Tumor Microenvironment: The Role of Chemokines – Part B
A Birbrair |
2021 | |
Tumor Microenvironment: The Role of Chemokines – Part B
A Birbrair |
2021 | |
Tumor Microenvironment: The Role of Chemokines – Part B
A Birbrair |
2021 | |
Tumor Microenvironment: The Role of Chemokines – Part B
A Birbrair |
2021 | |
Osteoblast role in the pathogenesis of rheumatoid arthritis
S Berardi, A Corrado, N Maruotti, D Cici, FP Cantatore |
Molecular Biology Reports | 2021 |
Macrophages: The Good, the Bad, and the Gluttony
EA Ross, A Devitt, JR Johnson |
Frontiers in immunology | 2021 |
Role of CCL2/CCR2 axis in the immunopathogenesis of rheumatoid arthritis: Latest evidence and therapeutic approaches
F Moadab, H Khorramdelazad, M Abbasifard |
Life Sciences | 2021 |
MCP-1: Function, regulation, and involvement in disease
S Singh, D Anshita, V Ravichandiran |
International Immunopharmacology | 2021 |
Low-Salt Diet Attenuates B-Cell- and Myeloid-Cell-Driven Experimental Arthritides by Affecting Innate as Well as Adaptive Immune Mechanisms
B Sehnert, S Pohle, C Heuberger, R Rzepka, M Seidl, F Nimmerjahn, N Chevalier, J Titze, RE Voll |
Frontiers in immunology | 2021 |
The 3p21.31 genetic locus promotes progression to type 1 diabetes through the CCR2/CCL2 pathway.
Tran PM, Purohit S, Kim E, Bin Satter K, Hopkins D, Waugh K, Dong F, Onengut-Gumuscu S, Rich SS, Rewers M, She JX |
2021 | |
Rheumatoid arthritis: Development after the emergence of a chemokine for neutrophils in the synovium
H Katayama |
BioEssays : news and reviews in molecular, cellular and developmental biology | 2021 |
Genetic Variation
RT Maia, M de Araújo Campos |
2021 | |
ORMDL3 overexpression facilitates FcεRI‐mediated transcription of proinflammatory cytokines and thapsigargin‐mediated PERK phosphorylation in RBL‐2H3 cells
K Ogi, T Takabayashi, K Tomita, M Sakashita, T Morikawa, T Ninomiya, M Okamoto, N Narita, S Fujieda |
Immunity, Inflammation and Disease | 2021 |
Exploring the role of monocyte chemoattractant protein-1 in fibroblast-like synovial cells in rheumatoid arthritis
X Tong, D Yu, L Yu, W Chen, Y Wen, P Gu |
PeerJ | 2021 |
Low levels of PCSK9 are associated with remission in patients with rheumatoid arthritis treated with anti-TNF-α: potential underlying mechanisms
J Frostegård, S Ahmed, I Hafström, S Ajeganova, M Rahman |
Arthritis Research & Therapy | 2021 |
Targeting CCN Proteins in Rheumatoid Arthritis and Osteoarthritis
IJ MacDonald, CC Huang, SC Liu, YY Lin, CH Tang |
International journal of molecular sciences | 2021 |
Mechanistic insights into the role of the chemokine CCL2/CCR2 axis in dorsal root ganglia to peripheral inflammation and pain hypersensitivity
MA Dansereau, É Midavaine, V Bégin-Lavallée, M Belkouch, N Beaudet, JM Longpré, S Mélik-Parsadaniantz, P Sarret |
Journal of Neuroinflammation | 2021 |
Sesquiterpene lactones; Damsin and neoambrosin suppress cytokine-mediated inflammation in complete Freund's adjuvant rat model via shutting Akt/ERK1/2/STAT3 signaling
SI Abdel-dayem, MN Khalil, EH Abdelrahman, HM El-Gohary, AS Kamel |
Journal of Ethnopharmacology | 2021 |
Circulating Level of Monocyte Chemoattractant Protein-1 and Risk of Coronary Artery Disease: A Case–Control and Mendelian Randomization Study
J Li, Y Zhang, X Guo, Y Wu, R Huang, X Han |
Pharmacogenomics and Personalized Medicine | 2021 |
The 3p21.31 genetic locus promotes progression to type 1 diabetes through the CCR2/CCL2 pathway
PM Tran, S Purohit, E Kim, K bin Satter, D Hopkins, K Waugh, F Dong, S Onengut-Gumuscu, SS Rich, M Rewers, JX She |
2021 | |
Ex vivo mass cytometry analysis reveals a profound myeloid proinflammatory signature in psoriatic arthritis synovial fluid
N Yager, S Cole, AL Lara, A Maroof, F Penkava, JC Knight, P Bowness, H Al-Mossawi |
Annals of the rheumatic diseases | 2021 |
Wilforlide A ameliorates the progression of rheumatoid arthritis by inhibiting M1 macrophage polarization
Y Cao, J Liu, C Huang, Y Tao, Y Wang, , D Huang |
Journal of Pharmacological Sciences | 2021 |
The Peripheral Role of CCL2 in the Anti-Nociceptive Effect of Sigma-1 Receptor Antagonist BD1047 on Inflammatory Hyperalgesia in Rats
S Chun, JH Lee, SY Yoon, YB Kwon |
International journal of molecular sciences | 2021 |
Nitro-fatty acids decrease type I interferons and monocyte chemoattractant protein 1 in ex vivo models of inflammatory arthritis.
Hansen AL, Rahbek LSJ, Sørensen AS, Hundahl MP, Lomholt S, Holm CK, Kragstrup TW |
BMC Immunology | 2021 |
Differentially Expressed Genes of Natural Killer Cells Can Distinguish Rheumatoid Arthritis Patients from Healthy Controls
NM Elemam, MY Hachim, S Hannawi, AA Maghazachi |
Genes & development | 2020 |
HIV-1 Tat: Role in Bystander Toxicity
D Ajasin, EA Eugenin |
Frontiers in Cellular and Infection Microbiology | 2020 |
Pharmacological targets of metabolism in disease: Opportunities from macrophages
A Castegna, R Gissi, A Menga, M Montopoli, M Favia, A Viola, M Canton |
Pharmacology & Therapeutics | 2020 |
Role of Nrf2 in rheumatoid arthritis
S Chadha, T Behl, A Kumar, G Khullar, S Arora |
Current Research in Translational Medicine | 2020 |
Transcriptional Regulation of Osteoclastogenesis: The Emerging Role of KLF2
D Rolph, H Das |
Frontiers in immunology | 2020 |
Rheumatoid arthritis synovial microenvironment induces metabolic and functional adaptations in dendritic cells
M Canavan, V Marzaioli, T McGarry, V Bhargava, S Nagpal, DJ Veale, U Fearon |
Clinical & Experimental Immunology | 2020 |
Dietary Short-Term Fiber Interventions in Arthritis Patients Increase Systemic SCFA Levels and Regulate Inflammation
K Dürholz, J Hofmann, A Iljazovic, J Häger, S Lucas, K Sarter, T Strowig, H Bang, J Rech, G Schett, MM Zaiss |
Nutrients | 2020 |
A novel monoclonal antibody cross-reactive with both human and mouse α9 integrin useful for therapy against rheumatoid arthritis
M Torikai, H Higuchi, N Yamamoto, D Ishikawa, H Fujita, K Taguchi, F Sakai, K Soejima, T Nakashima |
Journal of Biochemistry | 2020 |
Role of Chemokines and Chemokine Receptors in Rheumatoid Arthritis NM Elemam, S Hannawi, AA Maghazachi |
ImmunoTargets and Therapy | 2020 |
Intravenous injection of autologous bone marrow-derived mesenchymal stem cells on the gene expression and plasma level of CCL5 in refractory rheumatoid arthritis
M Alavi, J Tavakkol-Afshari, Z Shariati-Sarabi, AG Shabgah, M Ghoryani, A Ghasemi, M Mohammadi |
Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences | 2020 |
Dissecting the differential structural and dynamics features of CCL2 chemokine orthologs
N Joshi, N Nagar, K Gulati, K Gangele, A Mishra, D Kumar, KM Poluri |
International Journal of Biological Macromolecules | 2020 |
PBT-6, a Novel PI3KC2γ Inhibitor in Rheumatoid Arthritis
J Kim, KH Jung, J Yoo, JH Park, HH Yan, Z Fang, JH Lim, SR Kwon, MK Kim, HJ Park, SS Hong |
Biomolecules and Therapeutics | 2020 |
Cardiovascular Risk in Rheumatoid Arthritis and Mechanistic Links: From Pathophysiology to Treatment
GE Fragoulis, I Panayotidis, E Nikiphorou |
Current vascular pharmacology | 2020 |
Clinical Efficacy and Factors Predictive of the Therapeutic Effect of the TNF Inhibitor Golimumab in Patients with Rheumatoid Arthritis
N Sugisaki, K Tada, Y Abe, M Ogasawara, R Matsudaira, K Yamaji, Y Takasaki, N Tamura |
Juntendo Medical Journal | 2020 |
Immunomodulatory nanodiamond aggregate-based platform for the treatment of rheumatoid arthritis
A Pentecost, MJ Kim, S Jeon, YJ Ko, IC Kwon, Y Gogotsi, K Kim, KL Spiller |
Regenerative Biomaterials | 2019 |
Dexamethasone: chondroprotective corticosteroid or catabolic killer?
R Black, AJ Grodzinsky |
European Cells and Materials | 2019 |
Sequential CCL2 Expression Profile After Disc Injury in Mice
M Nakawaki, K Uchida, M Miyagi, Inoue, A Kawakubo, A Kuroda, M Satoh, M Takaso |
Journal of orthopaedic research : official publication of the Orthopaedic Research Society | 2019 |
Early Peritoneal CC Chemokine Production Correlates with Divergent Inflammatory Phenotypes and Susceptibility to Experimental Arthritis in Mice
C Rossato, LL Albuquerque, IS Katz, A Borrego, WH Cabrera, M Spadafora-Ferreira, OG Ribeiro, N Starobinas, OM Ibañez, MD Franco, JR Jensen |
Journal of Immunology Research | 2019 |
Comparative Transcriptomics Reveals the Role of the Toll-Like Receptor Signaling Pathway in Fluoride-Induced Cardiotoxicity
X Yan, N Dong, X Hao, Y Xing, X Tian, J Feng, J Xie, Y Lv, C Wei, Y Gao, Y Qiu, T Wang |
Journal of Agricultural and Food Chemistry | 2019 |
Peficitinib Inhibits the Chemotactic Activity of Monocytes via Proinflammatory Cytokine Production in Rheumatoid Arthritis Fibroblast-Like Synoviocytes
Y Ikari, T Isozaki, Y Tsubokura, T Kasama |
Cells | 2019 |
The many facets of macrophages in rheumatoid arthritis
E Siouti, E Andreakos |
Biochemical Pharmacology | 2019 |
Correlation between synovial fluid cytokine concentrations and limb function in normal dogs and in dogs with lameness from spontaneous osteoarthritis
PI Allen, MG Conzemius, RB Evans, K Kiefer |
Veterinary surgery : VS | 2019 |
Association of CCL2 Gene Variants with Osteoarthritis
Z Xu, J Li, H Yang, L Jiang, X Zhou, Y Huang, N Xu |
Archives of Medical Research | 2019 |
Histone deacetylases 1 and 2 inhibition suppresses cytokine production and osteoclast bone resorption in vitro
K Algate, D Haynes, T Fitzsimmons, O Romeo, F Wagner, E Holson, R Reid, D Fairlie, P Bartold, M Cantley |
Journal of Cellular Biochemistry | 2019 |
Responses to Cytokine Inhibitors Associated with Cellular Composition in Models of Immune‐Mediated Inflammatory Arthritis
MA Nielsen, S Lomholt, A Mellemkjær, MN Andersen, CD Buckley, TW Kragstrup |
2019 | |
Protective Role of Antioxidant Huskless Barley Extracts on TNF- α -Induced Endothelial Dysfunction in Human Vascular Endothelial Cells
Z Liao, H Cai, Z Xu, J Wang, C Qiu, J Xie, W Huang, Z Sui |
Oxidative medicine and cellular longevity | 2018 |
T Cells That Help B Cells in Chronically Inflamed Tissues
DA Rao |
Frontiers in immunology | 2018 |
Resolving Macrophages Counter Osteolysis by Anabolic Actions on Bone Cells
A Viniegra, H Goldberg, Ç Çil, N Fine, Z Sheikh, M Galli, M Freire, Y Wang, TE Dyke, M Glogauer, C Sima |
Journal of dental research | 2018 |
Inhibition of CCL3 abrogated precursor cell fusion and bone erosions in human osteoclast cultures and murine collagen-induced arthritis
LA Jordan, MC Erlandsson, BF Fenner, R Davies, AK Harvey, EH Choy, R Errington, MI Bokarewa, AS Williams |
Rheumatology | 2018 |
Immunomodulatory effects of phytogenics in chickens and pigs — A review
CM Huang, TT Lee |
Asian-Australasian Journal of Animal Sciences | 2018 |
Fibrosis in Disease: An Organ-Based Guide to Disease Pathophysiology and Therapeutic Considerations
MS Willis, CC Yates, JC Schisler |
2018 | |
NFAT5 Promotes Macrophage Survival in Rheumatoid Arthritis
Susanna Choi, Sungyong You, Donghyun Kim, Soo Youn Choi, H. Moo Kwon, Hyun-Sook Kim, Daehee Hwang, Yune-Jung Park, Chul-Soo Cho, Wan-Uk Kim |
Journal of Clinical Investigation | 2017 |
Synovial cellular and molecular markers in rheumatoid arthritis
MA Amin, DA Fox, JH Ruth |
Seminars in Immunopathology | 2017 |
Synovial tissue macrophages: friend or foe?
M Kurowska-Stolarska, S Alivernini |
RMD Open | 2017 |
New insights to the mechanisms underlying atherosclerosis in rheumatoid arthritis
M Mahmoudi, S Aslani, R Fadaei, AR Jamshidi |
International Journal of Rheumatic Diseases | 2017 |
CCL3 and MMP-9 are induced by TL1A during death receptor 3 (TNFRSF25)-dependent osteoclast function and systemic bone loss
FL Collins, JO Williams, AC Bloom, RK Singh, L Jordan, MD Stone, LR McCabe, EC Wang, AS Williams |
Bone | 2017 |
Synovial membrane receptors as therapeutic targets: A review of receptor localization, structure, and function: SYNOVIAL MEMBRANE RECEPTORS AS THERAPEUTIC TARGETS
SA Kleine, SC Budsberg |
Journal of Orthopaedic Research | 2017 |
Discovery of a junctional epitope antibody that stabilizes IL-6 and gp80 protein:protein interaction and modulates its downstream signaling
R Adams, RJ Burnley, CR Valenzano, O Qureshi, C Doyle, S Lumb, MC Lopez, R Griffin, D McMillan, RD Taylor, C Meier, P Mori, LM Griffin, U Wernery, J Kinne, S Rapecki, TS Baker, AD Lawson, M Wright, A Ettorre |
Scientific Reports | 2017 |
Increased interleukin (IL)-20 and IL-24 target osteoblasts and synovial monocytes in spondyloarthritis: IL-20 and IL-24 in SpA
TW Kragstrup, MN Andersen, B Schiøttz-Christensen, AG Jurik, M Hvid, B Deleuran |
Clinical & Experimental Immunology | 2017 |
Enhancement of CCL2 expression and monocyte migration by CCN1 in osteoblasts through inhibiting miR-518a-5p: implication of rheumatoid arthritis therapy
CY Chen, LJ Fuh, CC Huang, CJ Hsu, CM Su, SC Liu, YM Lin, CH Tang |
Scientific Reports | 2017 |
The Multifunctional Role of the Chemokine System in Arthritogenic Processes
G Bernardini, G Benigni, R Scrivo, G Valesini, A Santoni |
Current Rheumatology Reports | 2017 |
Resistin upregulates chemokine production by fibroblast-like synoviocytes from patients with rheumatoid arthritis
H Sato, S Muraoka, N Kusunoki, S Masuoka, S Yamada, H Ogasawara, T Imai, Y Akasaka, N Tochigi, H Takahashi, K Tsuchiya, S Kawai, T Nanki |
Arthritis Research & Therapy | 2017 |
IL-33/ST2-mediated inflammation in macrophages is directly abrogated by IL-10 during rheumatoid arthritis
S Chen, B Chen, Z Wen, Z Huang, L Ye |
Oncotarget | 2017 |
Withaferin-A, a steroidal lactone encapsulated mannose decorated liposomes ameliorates rheumatoid arthritis by intriguing the macrophage repolarization in adjuvant-induced arthritic rats
F Sultana, MK Neog, MK Rasool |
Colloids and surfaces. B, Biointerfaces | 2017 |
Tumor necrosis factor-alpha inhibitors suppress CCL2 chemokine in monocytes via epigenetic modification
YC Lin, YC Lin, MY Huang, PL Kuo, CC Wu, MS Lee, CC Hsieh, HF Kuo, CH Kuo, WC Tsai, CH Hung |
Molecular Immunology | 2017 |
Polymyalgia Rheumatica and Giant Cell Arteritis
J Rovenský, B Leeb, V Štvrtinová, R Imrich |
2017 | |
Treatment for rheumatoid arthritis by chemokine blockade
T NANKI |
Japanese Journal of Clinical Immunology | 2016 |
Macrophage heterogeneity in the context of rheumatoid arthritis
IA Udalova, A Mantovani, M Feldmann |
Nature Reviews Rheumatology | 2016 |
Parallel Aspects of the Microenvironment in Cancer and Autoimmune Disease
MA Rahat, J Shakya |
Mediators of Inflammation | 2016 |
C1q Modulates the Response to TLR7 Stimulation by Pristane-Primed Macrophages: Implications for Pristane-Induced Lupus
F Carlucci, A Ishaque, GS Ling, M Szajna, A Sandison, P Donatien, HT Cook, M Botto |
Journal of immunology (Baltimore, Md. : 1950) | 2016 |
Urinary interleukin-6 as a predictor of radiographic progression in rheumatoid arthritis: A 3-year evaluation
YJ Park, SA Yoo, GR Kim, CS Cho, WU Kim |
Scientific Reports | 2016 |
T cell migration in rheumatoid arthritis
M Mellado |
Frontiers in immunology | 2015 |
Inflammatory Cell Migration in Rheumatoid Arthritis: A Comprehensive Review
E Nevius, AC Gomes, JP Pereira |
Clinical Reviews in Allergy & Immunology | 2015 |
Activation of Nicotinic Receptors Inhibits TNF-α-Induced Production of Pro-inflammatory Mediators Through the JAK2/STAT3 Signaling Pathway in Fibroblast-Like Synoviocytes
T Li, S Wu, H Zhang, Y Wang, H Luo, X Zuo, X Xiao |
Inflammation | 2015 |
Increased Eotaxin and MCP-1 Levels in Serum from Individuals with Periodontitis and in Human Gingival Fibroblasts Exposed to Pro-Inflammatory Cytokines
EA Boström, E Kindstedt, R Sulniute, P Palmqvist, M Majster, CK Holm, S Zwicker, R Clark, S Önell, I Johansson, UH Lerner, P Lundberg, DM Ojcius |
PloS one | 2015 |
Therapeutic antibodies that target inflammatory cytokines in autoimmune diseases
Y Lai, C Dong |
International Immunology | 2015 |
Chemical Hypoxia Brings to Light Altered Autocrine Sphingosine-1-Phosphate Signalling in Rheumatoid Arthritis Synovial Fibroblasts
C Zhao, U Moreno-Nieves, JA di Battista, MJ Fernandes, M Touaibia, SG Bourgoin |
Mediators of Inflammation | 2015 |
Inhibiting histone deacetylase 1 suppresses both inflammation and bone loss in arthritis
MD Cantley, DP Fairlie, PM Bartold, V Marino, PK Gupta, DR Haynes |
Rheumatology | 2015 |
Serum concentrations of HGF and IL-8 in patients with active Graves’ orbitopathy before and after methylprednisolone therapy
M Nowak, L Siemińska, J Karpe, B Marek, B Kos-Kudła, D Kajdaniuk |
Journal of Endocrinological Investigation | 2015 |
Designing a mutant CCL2-HSA chimera with high glycosaminoglycan-binding affinity and selectivity
T Gerlza, S Winkler, A Atlic, C Zankl, V Konya, N Kitic, E Strutzmann, K Knebl, T Adage, A Heinemann, R Weis, AJ Kungl |
Protein Engineering Design and Selection | 2015 |
Successes and failures of chemokine-pathway targeting in rheumatoid arthritis
Z Szekanecz, AE Koch |
Nature Reviews Rheumatology | 2015 |
CCL2 and CCR2 are Essential for the Formation of Osteoclasts and Foreign Body Giant Cells: CCL2 IS E SSENTIAL F OR O STEOCLAST A ND F OREIGN B ODY G IANT C ELL F UNCTION
UA Khan, SM Hashimi, MM Bakr, MR Forwood, NA Morrison |
Journal of Cellular Biochemistry | 2015 |
Serum Copper as a Marker of Disease Activity in Rheumatoid Arthritis
M Chakraborty |
JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH | 2015 |
Colony-Specific Differences in Endocrine and Immune Responses to an Inflammatory Challenge in Female Sprague Dawley Rats
TS Bodnar, LA Hill, MD Taves, W Yu, KK Soma, GL Hammond, J Weinberg |
Endocrinology | 2015 |
Inflammatory Cytokine Response Following Acute Tibial Plateau Fracture:
JM Haller, M McFadden, EN Kubiak, TF Higgins |
The Journal of Bone and Joint Surgery. American volume. | 2015 |
5-Lipoxygenase Inhibitors Attenuate TNF-α-Induced Inflammation in Human Synovial Fibroblasts
HC Lin, TH Lin, MY Wu, YC Chiu, CH Tang, MJ Hour, HC Liou, HJ Tu, RS Yang, WM Fu, CM Yang |
PloS one | 2014 |
The degradation of chondrogenic pellets using cocultures of synovial fibroblasts and U937 cells
DJ Blasioli, GL Matthews, DL Kaplan |
Biomaterials | 2014 |
Non-Myeloid Cells are Major Contributors to Innate Immune Responses via Production of Monocyte Chemoattractant Protein-1/CCL2
T Yoshimura, C Galligan, M Takahashi, K Chen, M Liu, L Tessarollo, JM Wang |
Frontiers in immunology | 2014 |
Human cathelicidin LL-37 and its derivative IG-19 regulate interleukin-32-induced inflammation
KY Choi, S Napper, N Mookherjee |
Immunology | 2014 |
Mouse Monocyte Chemoattractant Protein 1 (MCP1) Functions as a Monomer
Y Yao, SE Tsirka |
The International Journal of Biochemistry & Cell Biology | 2014 |
Fucosyltransferase 1 Mediates Angiogenesis in Rheumatoid Arthritis: α(1,2)-Fucosylation by FUT1 is Expressed in RA
T Isozaki, MA Amin, JH Ruth, PL Campbell, PS Tsou, CM Ha, WA Stinson, SE Domino, AE Koch |
Arthritis & Rheumatology | 2014 |
Impact of periodontitis on chemokines in smokers
O Haytural, D Yaman, EC Ural, A Kantarci, K Demirel |
Clinical Oral Investigations | 2014 |
Helicobacter pylori protein HP0986 (TieA) interacts with mouse TNFR1 and triggers proinflammatory and proapoptotic signaling pathways in cultured macrophage cells (RAW 264.7)
SA Ansari, S Devi, S Tenguria, A Kumar, N Ahmed |
Cytokine | 2014 |
GPCR-targeting nanobodies: attractive research tools, diagnostics, and therapeutics
A Mujić-Delić, RH de Wit, F Verkaar, MJ Smit |
Trends in Pharmacological Sciences | 2014 |
Bone Disease in Newly Diagnosed Lupus Nephritis Patients
AL Resende, LM Reis, CB Dias, MR Custódio, V Jorgetti, V Woronik, NO Câmara |
PloS one | 2014 |
Synovial Joints: from Development to Homeostasis
L Longobardi, T Li, L Tagliafierro, JD Temple, HH Willcockson, P Ye, A Esposito, F Xu, A Spagnoli |
Current Osteoporosis Reports | 2014 |
Homing of mesenchymal stem cells: mechanistic or stochastic? Implications for targeted delivery in arthritis
OI Eseonu, CD Bari |
Rheumatology | 2014 |
Citrullination of Epithelial Neutrophil-Activating Peptide 78/CXCL5 Results in Conversion From a Non-Monocyte-Recruiting Chemokine to a Monocyte-Recruiting Chemokine: Citrullinated ENA-78/CXCL5 in Rheumatoid Arthritis
K Yoshida, O Korchynskyi, PP Tak, T Isozaki, JH Ruth, PL Campbell, DL Baeten, DM Gerlag, MA Amin, AE Koch |
Arthritis & Rheumatology | 2014 |
Etanercept ameliorates inflammation and pain in a novel mono-arthritic multi-flare model of streptococcal cell wall induced arthritis
K Chakravarthy, R Faltus, G Robinson, R Sevilla, J Shin, M Zielstorff, A Byford, E Leccese, MJ Caniga, SC Hseih, S Zhang, CS Chiu, J Zhang-Hoover, LY Moy, RL McLeod, D Stoffregen, W Zhang, A Murtaza, M Cicmil |
BMC musculoskeletal disorders | 2014 |
The active metabolite of spleen tyrosine kinase inhibitor fostamatinib abrogates the CD4+ T cell-priming capacity of dendritic cells
AM Platt, RA Benson, R McQueenie, JP Butcher, M Braddock, JM Brewer, IB McInnes, P Garside |
Rheumatology | 2014 |
Chemokines: Chemokines and Their Receptors in Drug Discovery
N Tschammer |
2014 | |
CC Chemokine Receptors and Chronic Inflammation—Therapeutic Opportunities and Pharmacological Challenges
GE White, AJ Iqbal, DR Greaves, CJ Garland |
Pharmacological reviews | 2013 |
Inflammatory monocyte mobilization decreases patient survival in pancreatic cancer: a role for targeting the CCL2/CCR2 axis
DE Sanford, BA Belt, RZ Panni, A Mayer, AD Deshpande, D Carpenter, JB Mitchem, SM Plambeck-Suess, LA Worley, BD Goetz, A Wang-Gillam, TJ Eberlein, DG Denardo, SP Goedegebuure, DC Linehan |
Clinical cancer research | 2013 |
Diverse activation of microglia by chemokine (C-C motif) ligand 2 overexpression in brain
ML Selenica, JA Alvarez, KR Nash, DC Lee, C Cao, X Lin, P Reid, PR Mouton, D Morgan, MN Gordon |
Journal of Neuroinflammation | 2013 |
Genetic component of giant cell arteritis
FD Carmona, MA Gonzalez-Gay, J Martin |
Rheumatology | 2013 |
The Roles of Catabolic Factors in the Development of Osteoarthritis
DJ Blasioli, DL Kaplan |
Tissue Engineering Part B: Reviews | 2013 |
Neutralizing nanobodies targeting diverse chemokines effectively inhibit chemokine function
C Blanchetot, D Verzijl, A Mujić-Delić, L Bosch, L Rem, R Leurs, CT Verrips, M Saunders, H Haard, MJ Smit |
The Journal of biological chemistry | 2013 |
Neutralizing Nanobodies Targeting Diverse Chemokines Effectively Inhibit Chemokine Function*
C Blanchetot, D Verzijl, A Mujić-Delić, L Bosch, L Rem, R Leurs, CT Verrips, M Saunders, H Haard, MJ Smit |
The Journal of biological chemistry | 2013 |
The role of circulating fibrocytes in inflammation and autoimmunity
CL Galligan, EN Fish |
Journal of leukocyte biology | 2013 |
Genetic and cellular evidence of decreased inflammation associated with reduced post-traumatic arthritis in MRL/MpJ mice
JS Lewis, BD Furman, E Zeitler, JL Huebner, VB Kraus, F Guilak, SA Olson |
Arthritis & Rheumatism | 2012 |
3D-QSAR studies on CCR2B receptor antagonists: Insight into the structural requirements of (R)-3-aminopyrrolidine series of molecules based on CoMFA/CoMSIA models
S Gade, S Mahmood |
Journal of Pharmacy & Bioallied Sciences | 2012 |
MicroRNAs in Rheumatoid Arthritis : Potential Role in Diagnosis and Therapy
M Filková, A Jüngel, RE Gay, S Gay |
BioDrugs | 2012 |
Minocycline Controls Clinical Outcomes and Inflammatory Cytokines in Moderate and Severe Meibomian Gland Dysfunction
H Lee, K Min, EK Kim, TI Kim |
American Journal of Ophthalmology | 2012 |
RANTES, MCP-1 chemokines and factors describing rheumatoid arthritis
MP Goldbergova, J Lipkova, N Pavek, J Gatterova, A Vasku, M Soucek, P Nemec |
Molecular Immunology | 2012 |
Apoptosis signal-regulating kinase 1 is mediated in TNF-α-induced CCL2 expression in human synovial fibroblasts
HK Tsou, HT Chen, CH Chang, WY Yang, CH Tang |
Journal of Cellular Biochemistry | 2012 |
Circulating fibrocytes contribute to the pathogenesis of collagen antibody-induced arthritis
CL Galligan, EN Fish |
Arthritis & Rheumatism | 2012 |
CTGF induces monocyte chemoattractant protein-1 expression to enhance monocyte migration in human synovial fibroblasts
SC Liu, CJ Hsu, YC Fong, SM Chuang, CH Tang |
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research | 2012 |
The role of a chemokine receptor, CCR2, in suppressing the development of arthritis in IL-1 receptor antagonist-deficient mice
H Fujii, T Baba, M Yamagishi, M Kawano, N Mukaida |
Inflammation and Regeneration | 2012 |
Suppression of endothelial cell activity by inhibition of TNFα
Q Shu, MA Amin, JH Ruth, PL Campbell, AE Koch |
Arthritis Research & Therapy | 2012 |
The CCL2/CCR2 Axis Enhances Vascular Cell Adhesion Molecule-1 Expression in Human Synovial Fibroblasts
YM Lin, CJ Hsu, YY Liao, MC Chou, CH Tang, S Grundmann |
PloS one | 2012 |
Cytokine biomarkers and chronic pain: Association of genes, transcription, and circulating proteins with temporomandibular disorders and widespread palpation tenderness
GD Slade, MS Conrad, L Diatchenko, NU Rashid, S Zhong, S Smith, J Rhodes, A Medvedev, S Makarov, W Maixner, AG Nackley |
PAIN | 2011 |
Evaluation of SV40-transformed synovial fibroblasts in the study of rheumatoid arthritis pathogenesis
KL Wagoner, RA Bader |
Rheumatology International | 2011 |
Targeting chemokine receptors in chronic inflammatory diseases: An extensive review
PJ Koelink, SA Overbeek, S Braber, P Kruijf, G Folkerts, MJ Smit, AD Kraneveld |
Pharmacology & Therapeutics | 2011 |
Recent Advances in Underlying Pathologies Provide Insight into Interleukin-8 Expression-Mediated Inflammation and Angiogenesis
BS Qazi, K Tang, A Qazi |
International Journal of Inflammation | 2011 |
Targeting interferon regulatory factors to inhibit activation of the type I IFN response: Implications for treatment of autoimmune disorders
SE Sweeney |
Cellular Immunology | 2011 |
Modulation of interleukin-1β-induced inflammatory responses by a synthetic cationic innate defence regulator peptide, IDR-1002, in synovial fibroblasts
E Turner-Brannen, KY Choi, DN Lippert, JP Cortens, RE Hancock, H El-Gabalawy, N Mookherjee |
Arthritis Research & Therapy | 2011 |
Methods and Principles in Medicinal Chemistry
AD Kraneveld, S Braber, S Overbeek, P Kruijf, P Koelink, MJ Smit |
Chemokine Receptors as Drug Targets | 2011 |
Cytokines
L Cassetta, G Poli, M Alfano |
Cytokines | 2011 |
Advances in Immunology
E Pinaud, M Marquet, R Fiancette, S Péron, C Vincent-Fabert, Y Denizot, M Cogné |
Advances in Immunology Volume 110 | 2011 |
First Pharmacophore Model of CCR3 Receptor Antagonists and its Homology Model-Assisted, Stepwise Virtual Screening
V Jain, P Saravanan, A Arvind, CG Mohan |
Chemical Biology & Drug Design | 2011 |
Anti-inflammatory activities of Chinese herbal medicine sinomenine and Liang Miao San on tumor necrosis factor-α-activated human fibroblast-like synoviocytes in rheumatoid arthritis
DP Chen, CK Wong, PC Leung, KP Fung, CB Lau, CP Lau, EK Li, LS Tam, CW Lam |
Journal of Ethnopharmacology | 2011 |
Interaction between oxidative stress and chemokines: Possible pathogenic role in systemic lupus erythematosus and rheumatoid arthritis
D Shah, A Wanchu, A Bhatnagar |
Immunobiology | 2011 |
Regulation of MMP-3 expression and secretion by the chemokine eotaxin-1 in human chondrocytes
PZ Chao, MS Hsieh, CW Cheng, YF Lin, CH Chen |
Journal of Biomedical Science | 2011 |
Annual Reports in Medicinal Chemistry
JJ Liu, TW Lee |
Annual Reports in Medicinal Chemistry Volume 46 | 2011 |
Interleukin-17A induction of angiogenesis, cell migration, and cytoskeletal rearrangement
EM Moran, M Connolly, W Gao, J McCormick, U Fearon, DJ Veale |
Arthritis & Rheumatism | 2011 |
Pulsed acoustic cellular expression as a protective therapy against I/R injury in a cremaster muscle flap model
L Krokowicz, A Klimczak, J Cwykiel, M Mielniczuk, C Grykien, M Siemionow |
Microvascular Research | 2011 |
Monocyte Chemoattractant Protein 1 Expression in Synovial Fluid of Patients With Total Hip Arthroplasty : MCP-1 EXPRESSION IN SYNOVIAL FLUID
M Montesi, A Beraudi, S Stea, C Ancarani, F Traina, A Toni |
Artificial Organs | 2011 |
Targeting Chemokines and Angiogenesis in Rheumatoid Arthritis
Z Szekanecz, AE Koch |
Pharmaceutical Sciences Encyclopedia Drug Discovery Development and Manufacturing | 2011 |
Natural Killer-22 Cells in the Synovial Fluid of Patients with Rheumatoid Arthritis Are an Innate Source of Interleukin 22 and Tumor Necrosis Factor-α
J Ren, Z Feng, Z Lv, XI Chen, J Li |
The Journal of rheumatology | 2011 |
Discovery, Optimization, and Pharmacological Characterization of Novel Heteroaroylphenylureas Antagonists of C−C Chemokine Ligand 2 Function
E Laborde, RW Macsata, F Meng, BT Peterson, L Robinson, SR Schow, RJ Simon, H Xu, K Baba, H Inagaki, Y Ishiwata, T Jomori, Y Matsumoto, A Miyachi, T Nakamura, M Okamoto, TM Handel, CC Bernard |
Journal of Medicinal Chemistry | 2011 |
Joint Tissues Amplify Inflammation and Alter Their Invasive Behavior via Leukotriene B 4 in Experimental Inflammatory Arthritis
M Chen, BK Lam, AD Luster, S Zarini, RC Murphy, AM Bair, RJ Soberman, DM Lee |
Journal of immunology (Baltimore, Md. : 1950) | 2010 |
Synovial effusion and synovial fluid biomarkers in psoriatic arthritis to assess intraarticular tumor necrosis factor-α blockade in the knee joint
U Fiocco, P Sfriso, F Oliviero, P Roux-Lombard, E Scagliori, L Cozzi, F Lunardi, F Calabrese, M Vezzù, S Dainese, B Molena, A Scanu, R Nardacchione, L Rubaltelli, JM Dayer, L Punzi |
Arthritis Research & Therapy | 2010 |
Pan–CC Chemokine Neutralization Restricts Splenocyte Egress and Reduces Inflammation in a Model of Arthritis
V Buatois, S Fagète, G Magistrelli, L Chatel, N Fischer, MH Kosco-Vilbois, WG Ferlin |
Journal of immunology (Baltimore, Md. : 1950) | 2010 |
Effects of inflammatory cytokine IL-27 on the activation of fibroblast-like synoviocytes in rheumatoid arthritis
CK Wong, DP Chen, LS Tam, EK Li, YB Yin, CW Lam |
Arthritis Research & Therapy | 2010 |
Burger's Medicinal Chemistry and Drug Discovery
S Bruno, L Ronda, S Faggiano, S Bettati, A Mozzarelli |
Burger's Medicinal Chemistry and Drug Discovery | 2010 |
Antiangiogenic phytochemicals and medicinal herbs
SJ Jeong, W Koh, EO Lee, HJ Lee, HJ Lee, H Bae, J Lü, SH Kim |
Phytotherapy Research | 2010 |
In vivo MR evaluation of the effect of the CCR2 antagonist on macrophage migration
Y Lee, JW Ryu, H Chang, JY Sohn, KW Lee, CW Woo, HJ Kang, SY Jeong, EK Choi, JS Lee |
Magnetic Resonance in Medicine | 2010 |
Effect of a phytotherapeutic agent, Eviprostat®, on prostatic and urinary cytokines/chemokines in a rat model of nonbacterial prostatitis
M Sugimoto, M Oka, H Tsunemori, M Yamashita, Y Kakehi |
The Prostate | 2010 |
Synoviocyte innate immune responses: II. Pivotal role of IFN regulatory factor 3
SE Sweeney, TB Kimbler, GS Firestein |
Journal of immunology (Baltimore, Md. : 1950) | 2010 |
Rationally evolving MCP-1/CCL2 into a decoy protein with potent anti-inflammatory activity in vivo
AM Piccinini, K Knebl, A Rek, G Wildner, M Diedrichs-Möhring, AJ Kungl |
The Journal of biological chemistry | 2010 |
Therapeutic potential of human umbilical cord mesenchymal stem cells in the treatment of rheumatoid arthritis
Y Liu, R Mu, S Wang, L Long, X Liu, R Li, J Sun, J Guo, X Zhang, J Guo, P Yu, C Li, X Liu, Z Huang, D Wang, H Li, Z Gu, B Liu, Z Li |
Arthritis Research & Therapy | 2010 |
Chemokines and chemokine receptors in arthritis
Z Szekanecz, A Vegvari, Z Szabo, AE Koch |
Frontiers in bioscience (Scholar edition) | 2010 |
Association of candidate susceptible loci with chronic infection with hepatitis B virus in a Chinese population
DQ Chen, Y Zeng, J Zhou, L Yang, S Jiang, JD Huang, L Lu, BJ Zheng |
Journal of Medical Virology | 2010 |
Characterization of the KRN Cell Transfer Model of Rheumatoid Arthritis (KRN-CTM), a Chronic Yet Synchronized Version of the K/BxN Mouse
TP LaBranche, CL Hickman-Brecks, DM Meyer, CE Storer, MI Jesson, KM Shevlin, FA Happa, RA Barve, DJ Weiss, JC Minnerly, JL Racz, PM Allen |
The American Journal of Pathology | 2010 |
MCP-1: Chemoattractant with a role beyond immunity: A review
A Yadav, V Saini, S Arora |
Clinica Chimica Acta | 2010 |
Effects of hesperetin on the production of inflammatory mediators in IL-1β treated human synovial cells
EM Choi, YS Lee |
Cellular Immunology | 2010 |
Macrophage-colony stimulating factor and interleukin-34 induce chemokines in human whole blood
H Eda, J Zhang, RH Keith, M Michener, DR Beidler, JB Monahan |
Cytokine | 2010 |
Comparative quantitative structure–activity relationship study of some 1-aminocyclopentyl-3-carboxyamides as CCR2 inhibitors using stepwise MLR, FA-MLR, and GA-PLS
M Shahlaei, A Madadkar-Sobhani, A Fassihi, L Saghaie, D Shamshirian, H Sakhi |
Medicinal Chemistry Research | 2010 |
The role of microRNA in rheumatoid arthritis and other autoimmune diseases
V Furer, JD Greenberg, M Attur, SB Abramson, MH Pillinger |
Clinical Immunology | 2010 |
Current Topics in Membranes
TC Wagenknecht, Z Liu |
Structure and Function of Calcium Release Channels | 2010 |
Seric chemokines and chemokine receptors in eosinophils during acute human schistosomiasis mansoni
D Silveira-Lemos, A Teixeira-Carvalho, OA Martins-Filho, AL Souza-Soares, P Castro-Silva, MF Costa-Silva, PH Guimarães, HB Ferraz, LA Oliveira-Fraga, MM Teixeira, R Corrêa-Oliveira |
Memórias do Instituto Oswaldo Cruz | 2010 |
Rationally Evolving MCP-1/CCL2 into a Decoy Protein with Potent Anti-inflammatory Activity in Vivo
AM Piccinini, K Knebl, A Rek, G Wildner, M Diedrichs-Möhring, AJ Kungl |
The Journal of biological chemistry | 2010 |
MCP-1 Production in Temporomandibular Joint Inflammation
N Ogura, K Satoh, M Akutsu, M Tobe, K Kuyama, N Kuboyama, H Sakamaki, H Kujiraoka, T Kondoh |
Journal of dental research | 2010 |
The C Terminus of Mouse Monocyte Chemoattractant Protein 1 (MCP1) Mediates MCP1 Dimerization while Blocking Its Chemotactic Potency
Y Yao, SE Tsirka |
The Journal of biological chemistry | 2010 |
CCL2 and CCR2 variants are associated with skeletal muscle strength and change in strength with resistance training
BT Harmon, EF Orkunoglu-Suer, K Adham, JS Larkin, H Gordish-Dressman, PM Clarkson, PD Thompson, TJ Angelopoulos, PM Gordon, NM Moyna, LS Pescatello, PS Visich, RF Zoeller, MJ Hubal, LL Tosi, EP Hoffman, JM Devaney |
Journal of applied physiology | 2010 |
Galectin 3 induces a distinctive pattern of cytokine and chemokine production in rheumatoid synovial fibroblasts via selective signaling pathways
A Filer, M Bik, GN Parsonage, J Fitton, E Trebilcock, K Howlett, M Cook, K Raza, DL Simmons, AM Thomas, M Salmon, D Scheel-Toellner, JM Lord, GA Rabinovich, CD Buckley |
Arthritis & Rheumatism | 2009 |
Inhalation of Carbon Monoxide Ameliorates Collagen-induced Arthritis in Mice and Regulates the Articular Expression of IL-1β and MCP-1
T Takagi, Y Naito, M Inoue, S Akagiri, K Mizushima, O Handa, S Kokura, H Ichikawa, T Yoshikawa |
Inflammation | 2009 |
Green tea extract inhibits chemokine production, but up-regulates chemokine receptor expression, in rheumatoid arthritis synovial fibroblasts and rat adjuvant-induced arthritis
H Marotte, JH Ruth, PL Campbell, AE Koch, S Ahmed |
Rheumatology | 2009 |
Etanercept reduces the serum levels of macrophage chemotactic protein-1 in patients with rheumatoid arthritis
Y Kageyama, H Kobayashi, N Kato, M Shimazu |
Modern Rheumatology | 2009 |
Protein biochip array technology to monitor rituximab in rheumatoid arthritis
S Fabre, C Guisset, L Tatem, N Dossat, AM Dupuy, JD Cohen, JP Cristol, JP Daures, C Jorgensen |
Clinical & Experimental Immunology | 2009 |
Anti-inflammatory mechanism of tocilizumab, a humanized anti-IL-6R antibody: effect on the expression of chemokine and adhesion molecule
M Suzuki, M Hashizume, H Yoshida, M Mihara |
Rheumatology International | 2009 |
Folate/homocysteine phenotypes and MTHFR 677C>T genotypes are associated with serum levels of monocyte chemoattractant protein-1
AL Hammons, CM Summers, JV Woodside, H McNulty, JJ Strain, IS Young, L Murray, CA Boreham, JM Scott, LE Mitchell, AS Whitehead |
Clinical Immunology | 2009 |
Detection of Experimentally Induced Pulmonary Granuloma Inflammation in Monocyte Chemoattractant Protein-1 Reporter Mice
S Rajasekaran, VY Kao, MR Chen, AL Yang, CH Hsu, CT Chen, KM Lin |
Molecular Imaging and Biology | 2009 |
Serum chemokines in patients with rheumatoid arthritis treated with etanercept
PA Klimiuk, S Sierakowski, I Domyslawska, J Chwiecko |
Rheumatology International | 2009 |
MicroRNA-124a is a key regulator of proliferation and monocyte chemoattractant protein 1 secretion in fibroblast-like synoviocytes from patients with rheumatoid arthritis
Y Nakamachi, S Kawano, M Takenokuchi, K Nishimura, Y Sakai, T Chin, R Saura, M Kurosaka, S Kumagai |
Arthritis & Rheumatism | 2009 |
Systemic inflammation as a driver of vascular calcification: a proof of concept
E Shantsila, GY Lip |
Journal of Internal Medicine | 2009 |
Galectin-1 stimulates monocyte chemotaxis via the p44/42 MAP kinase pathway and a pertussis toxin-sensitive pathway
RK Malik, RR Ghurye, DJ Lawrence-Watt, HJ Stewart |
Glycobiology | 2009 |
MCP-1 expressed by osteoclasts stimulates osteoclastogenesis in an autocrine/paracrine manner
K Miyamoto, K Ninomiya, KH Sonoda, Y Miyauchi, H Hoshi, R Iwasaki, H Miyamoto, S Yoshida, Y Sato, H Morioka, K Chiba, K Egashira, T Suda, Y Toyama, T Miyamoto |
Biochemical and Biophysical Research Communications | 2009 |
Genetic variants of CC chemokine genes in experimental autoimmune encephalomyelitis, multiple sclerosis and rheumatoid arthritis
J Öckinger, P Stridh, AD Beyeen, F Lundmark, M Seddighzadeh, A Oturai, PS Sørensen, ÅR Lorentzen, EG Celius, V Leppä, K Koivisto, PJ Tienari, L Alfredsson, L Padyukov, J Hillert, I Kockum, M Jagodic, T Olsson |
Genes and Immunity | 2009 |
Role of osteopontin in induction of monocyte chemoattractant protein 1 and macrophage inflammatory protein 1β through the NF-κB and MAPK pathways in rheumatoid arthritis
W Zheng, R Li, H Pan, D He, R Xu, TB Guo, Y Guo, JZ Zhang |
Arthritis & Rheumatism | 2009 |
Flavonol-rich RVHxR from Rhus verniciflua Stokes and its major compound fisetin inhibits inflammation-related cytokines and angiogenic factor in rheumatoid arthritic fibroblast-like synovial cells and in vivo models
JD Lee, JE Huh, GS Jeon, HR Yang, HS Woo, DY Choi, DS Park |
International Immunopharmacology | 2009 |
Synovial Fibroblasts: Important Players in the Induction of Inflammation and Joint Destruction
C Ospelt, T Pap, S Gay |
Rheumatoid Arthritis | 2009 |
Chemokines
JE Pease, TJ Williams |
Asthma and COPD | 2009 |
Monocyte Chemotactic Protein-1 (MCP-1) and Growth Factors Called into Question as Markers of Prolonged Psychosocial Stress
IH Jonsdottir, DA Hägg, K Glise, R Ekman, O Rotzschke |
PloS one | 2009 |
CXCL 9 and CXCL 10 as Sensitive Markers of Disease Activity in Patients with Rheumatoid Arthritis
WP Kuan, LS Tam, CK Wong, FW Ko, T Li, T Zhu, EK Li |
The Journal of rheumatology | 2009 |
New Therapeutic Targets in Rheumatoid Arthritis
PP Tak |
2009 | |
Gender Differences in Abdominal Aortic Aneurysms
KK Hannawa, JL Eliason, GR Upchurch |
Vascular | 2009 |
The Development of Novel Therapies for Rheumatoid Arthritis
LD Quan, GM Thiele, J Tian, D Wang |
Expert Opinion on Therapeutic Patents | 2008 |
Inhibition of Monocyte Chemoattractant Protein-1 Ameliorates Rat Adjuvant-Induced Arthritis
S Shahrara, AE Proudfoot, CC Park, MV Volin, GK Haines, JM Woods, CH Aikens, TM Handel, RM Pope |
Journal of immunology (Baltimore, Md. : 1950) | 2008 |
Differentially expressed genes in MHC-compatible rat strains that are susceptible or resistant to experimental autoimmune uveitis
MJ Mattapallil, A Augello, C Cheadle, D Teichberg, KG Becker, CC Chan, JJ Mattapallil, G Pennesi, RR Caspi |
Investigative ophthalmology & visual science | 2008 |
Human Immunodeficiency Virus (HIV) Infects Human Arterial Smooth Muscle Cells in Vivo and in Vitro
EA Eugenin, S Morgello, ME Klotman, A Mosoian, PA Lento, JW Berman, AD Schecter |
The American Journal of Pathology | 2008 |
Molecular aspects of rheumatoid arthritis: chemokines in the joints of patients
T Iwamoto, H Okamoto, Y Toyama, S Momohara |
FEBS Journal | 2008 |
Monocyte Chemoattractant Protein-1 and Macrophage Inflammatory Protein-1α as Possible Biomarkers for the Chronic Pelvic Pain Syndrome
NV Desireddi, PL Campbell, JA Stern, R Sobkoviak, S Chuai, S Shahrara, P Thumbikat, RM Pope, JR Landis, AE Koch, AJ Schaeffer |
The Journal of Urology | 2008 |
Common inflammatory mediators orchestrate pathophysiological processes in rheumatoid arthritis and atherosclerosis
F Montecucco, F Mach |
Rheumatology | 2008 |
Pathway analysis of seven common diseases assessed by genome-wide association
A Torkamani, EJ Topol, NJ Schork |
Genomics | 2008 |
Protein biochip array technology for cytokine profiling predicts etanercept responsiveness in rheumatoid arthritis
S Fabre, AM Dupuy, N Dossat, C Guisset, JD Cohen, JP Cristol, JP Daures, C Jorgensen |
Clinical & Experimental Immunology | 2008 |
The role of chemokines in leucocyte-stromal interactions in rheumatoid arthritis
A Filer, K Raza, M Salmon, CD Buckley |
Frontiers in bioscience : a journal and virtual library | 2008 |
The changes in serum chemokines following leflunomide therapy in patients with rheumatoid arthritis
PA Klimiuk, J Kita, J Chwiecko, S Sierakowski |
Clinical Rheumatology | 2008 |
Localization of S100A8 and S100A9 expressing neutrophils to spinal cord during peripheral tissue inflammation
K Mitchell, HY Yang, PA Tessier, WT Muhly, WD Swaim, I Szalayova, JM Keller, E Mezey, MJ Iadarola |
PAIN | 2008 |
Activation of peroxisome proliferator-activated receptor γ inhibits TNF-α-mediated osteoclast differentiation in human peripheral monocytes in part via suppression of monocyte chemoattractant protein-1 expression
H Hounoki, E Sugiyama, SG Mohamed, K Shinoda, H Taki, HO Abdel-Aziz, M Maruyama, M Kobayashi, T Miyahara |
Bone | 2008 |
Modulation of CCR2 in rheumatoid arthritis: A double‐blind, randomized, placebo‐controlled clinical trial
CE Vergunst, DM Gerlag, L Lopatinskaya, L Klareskog, MD Smith, F Bosch, HJ Dinant, Y Lee, T Wyant, EW Jacobson, D Baeten, PP Tak |
Arthritis & Rheumatism | 2008 |
Investigational C-C chemokine receptor 2 antagonists for the treatment of autoimmune diseases
A Kalinowska, J Losy |
Expert Opinion on Investigational Drugs | 2008 |
Potent heteroarylpiperidine and carboxyphenylpiperidine 1-alkyl-cyclopentane carboxamide CCR2 antagonists
A Pasternak, SD Goble, PP Vicario, JD Salvo, JM Ayala, M Struthers, JA DeMartino, SG Mills, L Yang |
Bioorganic & Medicinal Chemistry Letters | 2008 |
Conformational studies of 3-amino-1-alkyl-cyclopentane carboxamide CCR2 antagonists leading to new spirocyclic antagonists
A Pasternak, SD Goble, GA Doss, NN Tsou, G Butora, PP Vicario, JM Ayala, M Struthers, JA DeMartino, SG Mills, L Yang |
Bioorganic & Medicinal Chemistry Letters | 2008 |
Anti-inflammatory Activity of an Ethanol Extract of Caesalpinia sappan L. in LPS-induced RAW 264.7 Cells
IY Jeong, CH Jin, YD Park, HJ Lee, DS Choi, MW Byun, YJ Kim |
Journal of Food Science and Nutrition | 2008 |
Facilitating action of asiaticoside at low doses on burn wound repair and its mechanism
Y Kimura, M Sumiyoshi, K Samukawa, N Satake, M Sakanaka |
European Journal of Pharmacology | 2008 |
Efficient Inhibition of Hepatitis B Virus ReplicationIn Vivo, Using Polyethylene Glycol-Modified Adenovirus Vectors
C Crowther, A Ely, J Hornby, S Mufamadi, F Salazar, P Marion, P Arbuthnot |
Human Gene Therapy | 2008 |
Effects of ginsenoside Rb1 at low doses on histamine, substance P, and monocyte chemoattractant protein 1 in the burn wound areas during the process of acute burn wound repair
K Kawahira, M Sumiyoshi, M Sakanaka, Y Kimura |
Journal of Ethnopharmacology | 2008 |
Cells of the synovium in rheumatoid arthritis. Dendritic cells
V Lutzky, S Hannawi, R Thomas |
Arthritis Research & Therapy | 2007 |
Interferon-gamma protects against the development of structural damage in experimental arthritis by regulating polymorphonuclear neutrophil influx into diseased joints
AS Williams, PJ Richards, E Thomas, S Carty, MA Nowell, RM Goodfellow, CM Dent, BD Williams, SA Jones, N Topley |
Arthritis & Rheumatism | 2007 |
Targeting of Gr-1+,CCR2+ monocytes in collagen-induced arthritis
H Brühl, J Cihak, J Plachý, L Kunz-Schughart, M Niedermeier, A Denzel, MR Gomez, Y Talke, B Luckow, M Stangassinger, M Mack |
Arthritis & Rheumatism | 2007 |
Antiviral gene expression in rheumatoid arthritis: Role of IKKε and interferon regulatory factor 3
SE Sweeney, L Mo, GS Firestein |
Arthritis & Rheumatism | 2007 |
Nutraceutical Science and Technology
N Bhaskar, K Miyashita |
Anti-Angiogenic Functional and Medicinal Foods | 2007 |
MECHANISMS OF OXIDANT REGULATION OF MONOCYTE CHEMOTACTIC PROTEIN 1 PRODUCTION IN HUMAN WHOLE BLOOD AND ISOLATED MONONUCLEAR CELLS
L Xing, DG Remick |
Shock | 2007 |
Hepatocyte growth factor induction of macrophage chemoattractant protein-1 and osteophyte-inducing factors in osteoarthritis
B Dankbar, K Neugebauer, C Wunrau, CO Tibesku, A Skwara, T Pap, S Fuchs-Winkelmann |
Journal of Orthopaedic Research | 2007 |
Downregulation of Monocyte Chemoattractant Protein-1 Involving Short Interfering RNA Attenuates Hapten-induced Contact Hypersensitivity
T Ishimoto, Y Takei, Y Yuzawa, K Hanai, S Nagahara, Y Tarumi, S Matsuo, K Kadomatsu |
Molecular Therapy | 2007 |
Primary central nervous system lymphoma secretes monocyte chemoattractant protein 1
R Kitai, K Ishisaka, K Sato, T Sakuma, T Yamauchi, Y Imamura, H Matsumoto, T Kubota |
Medical Molecular Morphology | 2007 |
Update on cytokines in rheumatoid arthritis
F Brennan, J Beech |
Current Opinion in Rheumatology | 2007 |
Diaryl substituted pyrazoles as potent CCR2 receptor antagonists
AB Pinkerton, D Huang, RV Cube, JH Hutchinson, M Struthers, JM Ayala, PP Vicario, SR Patel, T Wisniewski, JA DeMartino, JM Vernier |
Bioorganic & Medicinal Chemistry Letters | 2007 |
Mice overexpressing chemokine ligand 2 (CCL2) in astrocytes display enhanced nociceptive responses
J Menetski, S Mistry, M Lu, JS Mudgett, RM Ransohoff, JA DeMartino, DE MacIntyre, C Abbadie |
Neuroscience | 2007 |
Cell surface CCR5 density determines the intensity of T cell migration towards rheumatoid arthritis synoviocytes
C Desmetz, YL Lin, C Mettling, P Portalès, D Noël, J Clot, C Jorgensen, P Corbeau |
Clinical Immunology | 2007 |
Interleukin-18 induces angiogenic factors in rheumatoid arthritis synovial tissue fibroblasts via distinct signaling pathways
MA Amin, PJ Mansfield, A Pakozdi, PL Campbell, S Ahmed, RJ Martinez, AE Koch |
Arthritis & Rheumatism | 2007 |
Handbook of Neurochemistry and Molecular Neurobiology
VH Routh, JJ McArdle, NM Sanders, Z Song, R Wang |
Handbook of Neurochemistry and Molecular Neurobiology | 2007 |
Association of the −2510A/G chemokine (C–C motif) ligand 2 polymorphism with knee osteoarthritis in a Korean population
HJ Park, SH Yoon, LT Zheng, KH Lee, JW Kim, JH Chung, YA Lee, SJ Hong |
Scandinavian Journal of Rheumatology | 2007 |
Toll-Like Receptor 2-Dependent NF-κB Activation Is Involved in Nontypeable Haemophilus influenzae -Induced Monocyte Chemotactic Protein 1 Up-Regulation in the Spiral Ligament Fibrocytes of the Inner Ear
SK Moon, JI Woo, HY Lee, R Park, J Shimada, H Pan, R Gellibolian, DJ Lim |
Infection and immunity | 2007 |
Transcription factor T-bet regulates inflammatory arthritis through its function in dendritic cells
Jingsong Wang, John W. Fathman, Geanncarlo Lugo-Villarino, Lucila Scimone, Ulrich von Andrian, David M. Dorfman, and Laurie H. Glimcher |
Journal of Clinical Investigation | 2006 |
CXCL16-mediated cell recruitment to rheumatoid arthritis synovial tissue and murine lymph nodes is dependent upon the MAPK pathway
JH Ruth, CS Haas, CC Park, MA Amin, RJ Martinez, GK 3rd, S Shahrara, PL Campbell, AE Koch |
Arthritis & Rheumatism | 2006 |
Involvement of TNF-Like Weak Inducer of Apoptosis in the Pathogenesis of Collagen-Induced Arthritis
K Kamata, S Kamijo, A Nakajima, A Koyanagi, H Kurosawa, H Yagita, K Okumura |
Journal of immunology (Baltimore, Md. : 1950) | 2006 |
Differential effect of methotrexate on the increased CCR2 density on circulating CD4 T lymphocytes and monocytes in active chronic rheumatoid arthritis, with a down regulation only on monocytes in responders
T Ellingsen, N Hornung, BK Møller, JH Poulsen, K Stengaard-Pedersen |
Annals of the rheumatic diseases | 2006 |
IL-20: biological functions and clinical implications
CC Wei, YH Hsu, HH Li, YC Wang, MY Hsieh, WY Chen, CH Hsing, MS Chang |
Journal of Biomedical Science | 2006 |
Essential role of neutrophils in anti-type II collagen antibody and lipopolysaccharide-induced arthritis
D Tanaka, T Kagari, H Doi, T Shimozato |
Immunology | 2006 |
Allelic frequency of the MCP-1 promoter −2518 polymorphism in the Turkish population and in Turkish patients with juvenile rheumatoid arthritis
AR Özyürek, D Gürses, Z Ülger, E Levent, AR Bakiler, A Berdeli |
Clinical Rheumatology | 2006 |
The CCR2 receptor as a therapeutic target
M Feria, F Díaz-González |
Expert Opinion on Therapeutic Patents | 2006 |
Function of interleukin-20 as a proinflammatory molecule in rheumatoid and experimental arthritis
YH Hsu, HH Li, MY Hsieh, MF Liu, KY Huang, LS Chin, PC Chen, HH Cheng, MS Chang |
Arthritis & Rheumatism | 2006 |
Up regulation of monocyte chemoattractant protein-1 expression in anti-citrulline antibody and immunoglobulin M rheumatoid factor positive subjects precedes onset of inflammatory response and development of overt rheumatoid arthritis
S Rantapää-Dahlqvist, K Boman, A Tarkowski, G Hallmans |
Annals of the rheumatic diseases | 2006 |
T-cell contact-dependent regulation of CC and CXC chemokine production in monocytes through differential involvement of NFkappaB: implications for rheumatoid arthritis
JT Beech, E Andreakos, CJ Ciesielski, P Green, BM Foxwell, FM Brennan |
Arthritis Research & Therapy | 2006 |
Anti-tumor necrosis factor-alpha antibody treatment reduces serum CXCL16 levels in patients with rheumatoid arthritis
Y Kageyama, E Torikai, A Nagano |
Rheumatology International | 2006 |
Chemokine inhibition in inflammatory arthritis
PP Tak |
Best Practice & Research Clinical Rheumatology | 2006 |
RANTES and monocyte chemoattractant protein 1 as sensitive markers of disease activity in patients with juvenile rheumatoid arthritis: A six-year longitudinal study
TC Yao, ML Kuo, LC See, LS Ou, WI Lee, CK Chan, JL Huang |
Arthritis & Rheumatism | 2006 |
Novel therapies for rheumatoid arthritis
AH Tremoulet, S Albani |
Expert Opinion on Investigational Drugs | 2006 |
Triptolide inhibits CC chemokines expressed in rat adjuvant-induced arthritis
Y Wang, D Wei, Z Lai, Y Le |
International Immunopharmacology | 2006 |
Dynamics of Bone and Cartilage Metabolism
JE Mulder, CA Kulak, E Shane |
Dynamics of Bone and Cartilage Metabolism | 2006 |
Direct modulation of rheumatoid inflammatory mediator expression in retinoblastoma protein-dependent and -independent pathways by cyclin-dependent kinase 4/6
Y Nonomura, K Nagasaka, H Hagiyama, C Sekine, T Nanki, M Tamamori-Adachi, N Miyasaka, H Kohsaka |
Arthritis & Rheumatism | 2006 |
A New “Kine” of Pain: MCP-1 and Sensory Neuron Excitability . Focus on “MCP-1 Enhances Excitability of Nociceptive Neurons in Chronically Compressed Dorsal Root Ganglia”
CM Hingtgen |
Journal of neurophysiology | 2006 |
Elevated CXCL16 expression by synovial macrophages recruits memory T cells into rheumatoid joints
RV der Voort, AW van Lieshout, LW Toonen, AW Slöetjes, WB van Berg, CG Figdor, TR Radstake, GJ Adema |
Arthritis & Rheumatism | 2005 |
Role of glucocorticoid-induced TNF receptor family gene (GITR) in collagen-induced arthritis
S Cuzzocrea, E Ayroldi, RD Paola, M Agostini, E Mazzon, S Bruscoli, T Genovese, S Ronchetti, AP Caputi, C Riccardi |
The FASEB Journal | 2005 |
Chemokines: Their role in rheumatoid arthritis
CE Vergunst, PP Tak |
Current Rheumatology Reports | 2005 |
The role of chemokines in rheumatoid arthritis and osteoarthritis
CE Vergunst, MG van de Sande, MC Lebre, PP Tak |
Scandinavian Journal of Rheumatology | 2005 |
HIV-1 tat protein induces a migratory phenotype in human fetal microglia by a CCL2 (MCP-1)-dependent mechanism: Possible role in NeuroAIDS
EA Eugenin, G Dyer, TM Calderon, JW Berman |
Glia | 2005 |
Partial protection against collagen antibody-induced arthritis in PARP-1 deficient mice
S García, A Bodaño, A González, J Forteza, JJ Gómez-Reino, C Conde |
Arthritis Research & Therapy | 2005 |
Levels of gastrin-releasing peptide and substance P in synovial fluid and serum correlate with levels of cytokines in rheumatoid arthritis
O Grimsholm, S Rantapää-Dahlqvist, S Forsgren |
Arthritis Research & Therapy | 2005 |
Expression of interleukin-22 in rheumatoid arthritis: Potential role as a proinflammatory cytokine
H Ikeuchi, T Kuroiwa, N Hiramatsu, Y Kaneko, K Hiromura, K Ueki, Y Nojima |
Arthritis & Rheumatism | 2005 |
An angiotensin receptor blocker suppresses monocyte chemoattractant protein 1 production from rheumatoid synovial fibroblasts: Comment on the article by Sagawa et al
N Iikuni, H Okamoto, M Kasahara, N Kamatani |
Arthritis & Rheumatism | 2005 |
Tumor necrosis factor-alpha increases chemokine gene expression and production in synovial fibroblasts from human temporomandibular joint
N Ogura, M Tobe, H Sakamaki, H Nagura, Y Abiko, T Kondoh |
Journal of Oral Pathology and Medicine | 2005 |
The expression of CCL2 by T lymphocytes of mammary tumor bearers: Role of tumor-derived factors
JL Owen, DM Lopez, JF Grosso, KM Guthrie, LM Herbert, M Torroella-Kouri, V Iragavarapu-Charyulu |
Cellular Immunology | 2005 |
Anti-inflammatory and analgesic effects of atorvastatin in a rat model of adjuvant-induced arthritis
MM Barsante, E Roffê, CM Yokoro, WL Tafuri, DG Souza, V Pinho, MS de Castro, MM Teixeira |
European Journal of Pharmacology | 2005 |
MCP-1-stimulated chemotaxis of monocytic and endothelial cells is dependent on activation of different signaling cascades
TI Arefieva, NB Kukhtina, OA Antonova, TL Krasnikova |
Cytokine | 2005 |
NeuroImmune Biology
R Solana, G Pawelec |
NeuroImmune Biology | 2005 |
Chemokines and their receptors in rheumatoid arthritis: Future targets?
AE Koch |
Arthritis & Rheumatism | 2005 |
Inhibition of the angiogenesis by the MCP-1 (monocyte chemoattractant protein-1) binding peptide
MY Kim, CW Byeon, KH Hong, KH Han, S Jeong |
FEBS Letters | 2005 |
Chemokines in rheumatoid arthritis
P Loetscher |
Drug Discovery Today: Disease Mechanisms | 2005 |
Profiling of differentially expressed chemotactic-related genes in MCP-1 treated macrophage cell line using human cDNA arrays
Guang-Xing Bian, Hong Miao, Lei Qiu, Dong-Mei Cao, Bao-Yu Guo |
World journal of gastroenterology : WJG | 2005 |
A CCR-5 antagonist inhibits the development of adjuvant arthritis in rats
H Okamoto, N Kamatani |
Rheumatology (Oxford, England) | 2005 |
AGIX-4207 [2-[4-[[1-[[3,5-Bis(1,1-dimethylethyl)-4-hydroxyphenyl]thio]-1-methylethyl]thio]-2,6-bis(1,1-dimethylethyl)phenoxy]acetic Acid], a Novel Antioxidant and Anti-Inflammatory Compound: Cellular and Biochemical Characterization of Antioxidant Activity and Inhibition of Redox-Sensitive Inflammatory Gene Expression
C Kunsch, J Luchoomun, , GL Dodd, KS Karu, CQ Meng, EM Marino, LK Olliff, JD Piper, FH Qiu, JA Sikorski, PK Somers, KL Suen, S Thomas, AM Whalen, MA Wasserman, CL Sundell |
The Journal of pharmacology and experimental therapeutics | 2005 |
IL-18 Induces Monocyte Chemotactic Protein-1 Production in Macrophages through the Phosphatidylinositol 3-Kinase/Akt and MEK/ERK1/2 Pathways
JK Yoo, H Kwon, LY Khil, L Zhang, HS Jun, JW Yoon |
Journal of immunology (Baltimore, Md. : 1950) | 2005 |
Dual role of CCR2 during initiation and progression of collagen-induced arthritis: evidence for regulatory activity of CCR2+ T cells
H Brühl, J Cihak, MA Schneider, J Plachý, T Rupp, I Wenzel, M Shakarami, S Milz, JW Ellwart, M Stangassinger, D Schlöndorff, M Mack |
Journal of immunology (Baltimore, Md. : 1950) | 2004 |
Key Roles of CD4 + T Cells and IFN-γ in the Development of Abdominal Aortic Aneurysms in a Murine Model
W Xiong, Y Zhao, A Prall, TC Greiner, BT Baxter |
Journal of immunology (Baltimore, Md. : 1950) | 2004 |
Chemokines in joint disease: the key to inflammation?
JJ Haringman, J Ludikhuize, PP Tak |
Annals of the rheumatic diseases | 2004 |
Inhibition of TNF alpha during maturation of dendritic cells results in the development of semi-mature cells: a potential mechanism for the beneficial effects of TNF alpha blockade in rheumatoid arthritis
AW van Lieshout, P Barrera, RL Smeets, GJ Pesman, PL van Riel, WB van Berg, TR Radstake |
Annals of the rheumatic diseases | 2004 |
Retinoblastoma suppression of matrix metalloproteinase 1, but not interleukin-6, through a p38-dependent pathway in rheumatoid arthritis synovial fibroblasts
K Bradley, JC Scatizzi, S Fiore, E Shamiyeh, AE Koch, GS Firestein, LL Gorges, K Kuntsman, RM Pope, TL Moore, J Han, H Perlman |
Arthritis & Rheumatism | 2004 |
Production of the chemokine eotaxin-1 in osteoarthritis and its role in cartilage degradation
YH Hsu, MS Hsieh, YC Liang, CY Li, MT Sheu, DT Chou, TF Chen, CH Chen |
Journal of Cellular Biochemistry | 2004 |
Augmented production of chemokines by the interaction of type II collagen-reactive T cells with rheumatoid synovial fibroblasts
DJ Min, ML Cho, SH Lee, SY Min, WU Kim, JK Min, SH Park, CS Cho, HY Kim |
Arthritis & Rheumatism | 2004 |
Type II Collagen Autoimmunity in Rheumatoid Arthritis
WU Kim, ML Cho, YO Jung, SY Min, SW Park, DJ Min, JH Yoon, HY Kim |
The American Journal of the Medical Sciences | 2004 |
Anti-Monocyte Chemoattractant Protein-1 Gene Therapy Protects Against Focal Brain Ischemia in Hypertensive Rats
Y Kumai, H Ooboshi, J Takada, M Kamouchi, T Kitazono, K Egashira, S Ibayashi, M Iida |
Journal of Cerebral Blood Flow & Metabolism | 2004 |
N-Benzylindole-2-carboxylic acids: potent functional antagonists of the CCR2b chemokine receptor
JG Kettle, AW Faull, AJ Barker, DH Davies, MA Stone |
Bioorganic & Medicinal Chemistry Letters | 2004 |
Matrix metalloproteinases and the immune response
KA Szabo, RJ Ablin, G Singh |
Clinical and Applied Immunology Reviews | 2004 |
Development of a microplate bioassay for monocyte chemoattractant protein-1 based on activation of p44/42 mitogen-activated protein kinase
JH Terra, I Montaño, A Schilb, TA Millward |
Analytical Biochemistry | 2004 |
Hypoxia Selectively Inhibits Monocyte Chemoattractant Protein-1 Production by Macrophages
MC Bosco, M Puppo, S Pastorino, Z Mi, G Melillo, S Massazza, A Rapisarda, L Varesio |
Journal of immunology (Baltimore, Md. : 1950) | 2004 |
IL-6 and matrix metalloproteinase-1 are regulated by the cyclin-dependent kinase inhibitor p21 in synovial fibroblasts
H Perlman, K Bradley, H Liu, S Cole, E Shamiyeh, RC Smith, K Walsh, S Fiore, AE Koch, GS Firestein, GK 3rd, RM Pope |
Journal of immunology (Baltimore, Md. : 1950) | 2003 |
Gene transfer of a cell cycle modulator exerts anti-inflammatory effects in the treatment of arthritis
Y Nonomura, H Kohsaka, K Nagasaka, N Miyasaka |
Journal of immunology (Baltimore, Md. : 1950) | 2003 |
Chemokine-dependent mechanisms of leukocyte trafficking across a model of the blood–brain barrier
EA Eugenin, JW Berman |
Methods | 2003 |
Targeting monocyte chemoattractant protein-1 signalling in disease
J Dawson, W Miltz, AK Mir, C Wiessner |
Expert Opinion on Therapeutic Targets | 2003 |
The therapeutic potential of costimulatory blockade with CTLA4Ig in rheumatoid arthritis
P Emery |
Expert Opinion on Investigational Drugs | 2003 |
Chemokines and chemokine receptors in rheumatoid arthritis
Z Szekanecz, J Kim, AE Koch |
Seminars in Immunology | 2003 |
Pathophysiological roles for IL-18 in inflammatory arthritis
K Matsui, H Tsutsui, K Nakanishi |
Expert Opinion on Therapeutic Targets | 2003 |
Hydrodynamic guiding for addressing subsets of immobilized cells and molecules in microfluidic systems
T Brevig, U Krühne, RA Kahn, T Ahl, M Beyer, LH Pedersen |
BMC Biotechnology | 2003 |
Impaired hepatic granuloma formation in mice deficient in C–C chemokine receptor 2
K Jinnouchi, Y Terasaki, S Fujiyama, K Tomita, WA Kuziel, N Maeda, K Takahashi, M Takeya |
The Journal of Pathology | 2003 |
MCP-1 promoter polymorphism in spanish patients with rheumatoid arthritis
MF González-Escribano, B Torres, F Aguilar, R Rodríguez, A García, Á Valenzuela, A Núñez-Roldán |
Human Immunology | 2003 |
The role of the beta chemokines in experimental obliterative bronchiolitis
AS Farivar, B Krishnadasan, BV Naidu, SM Woolley, MS Mulligan |
Experimental and Molecular Pathology | 2003 |
Reduction in the evolution of murine type II collagen-induced arthritis by treatment with rosiglitazone, a ligand of the peroxisome proliferator-activated receptor gamma
S Cuzzocrea, E Mazzon, L Dugo, NS Patel, I Serraino, RD Paola, T Genovese, D Britti, MD Maio, AP Caputi, C Thiemermann |
Arthritis & Rheumatism | 2003 |
Effects of bacterial cell wall components (PAMPs) on the expression of monocyte chemoattractant protein-1 (MCP-1), macrophage inflammatory protein-1α (MIP-1α) and the chemokine receptor CCR2 by purified human blood monocytes
AS Møller, R Øvstebø, ÅB Westvik, GB Joø, KB Haug, P Kierulf |
Journal of Endotoxin Research | 2003 |
Monocyte chemoattractant protein 3 as a mediator of fibrosis: Overexpression in systemic sclerosis and the type 1 tight-skin mouse
VH Ong, LA Evans, X Shiwen, IB Fisher, V Rajkumar, DJ Abraham, CM Black, CP Denton |
Arthritis & Rheumatism | 2003 |
The Macrophage as Therapeutic Target
S Gordon |
2003 | |
Mice lacking monocyte chemoattractant protein 1 have enhanced susceptibility to an interstitial polymicrobial infection due to impaired monocyte recruitment
P Chae, M Im, F Gibson, Y Jiang, DT Graves |
Infection and immunity | 2002 |
Stromal cell-derived factor 1 (CXCL12) induces monocyte migration into human synovium transplanted onto SCID Mice
MC Blades, F Ingegnoli, SK Wheller, A Manzo, S Wahid, GS Panayi, M Perretti, C Pitzalis |
Arthritis & Rheumatism | 2002 |
Stromal cell-derived factor 1 (CXCL12) induces monocyte migration into human synovium transplanted onto SCID Mice
MC Blades, F Ingegnoli, SK Wheller, A Manzo, S Wahid, GS Panayi, M Perretti, C Pitzalis |
Arthritis & Rheumatism | 2002 |
Angiogenesis and chemokines in rheumatoid arthritis and other systemic inflammatory rheumatic diseases
E Bodolay, AE Koch, J Kim, G Szegedi, Z Szekanecz |
Journal of Cellular and Molecular Medicine | 2002 |
Monocyte Chemoattractant Protein-1-Induced Activation of p42/44 MAPK and c-Jun in Murine Peritoneal Macrophages: A Potential Pathway for Macrophage Activation
A Sodhi, SK Biswas |
Journal of Interferon & Cytokine Research | 2002 |
Expression of the Duffy antigen/receptor for chemokines (DARC) by the inflamed synovial endothelium
AM Patterson, H Siddall, G Chamberlain, L Gardner, J Middleton |
The Journal of Pathology | 2002 |
Alanine scanning mutagenesis of CCR3 reveals that the three intracellular loops are essential for functional receptor expression
GA Auger, JE Pease, X Shen, G Xanthou, MD Barker |
European Journal of Immunology | 2002 |
Slit proteins, potential endogenous modulators of inflammation
N Havlioglu, L Yuan, H Tang, JY Wu |
Journal of Neurovirology | 2002 |
Leucocyte chemotaxis: Examination of mitogen-activated protein kinase and phosphoinositide 3-kinase activation by Monocyte Chemoattractant Proteins-1, -2, -3 and -4
JH Wain, JA Kirby, S Ali |
Clinical & Experimental Immunology | 2002 |
Interleukin-13 Gene Therapy Reduces Inflammation, Vascularization, and Bony Destruction in Rat Adjuvant-Induced Arthritis
JM Woods, MA Amin, KJ Katschke, MV Volin, JH Ruth, MA Connors, DC Woodruff, H Kurata, KI Arai, GK Haines, P Kumar, AE Koch |
Human Gene Therapy | 2002 |
Differential production of RANTES and MCP-1 in synovial fluid from the inflamed human knee
P Conti, M Reale, RC Barbacane, ML Castellani, C Orso |
Immunology Letters | 2002 |
Differential Expression of the Isoforms for the Monocyte Chemoattractant Protein-1 Receptor, CCR2, in Monocytes
S Tanaka, SR Green, O Quehenberger |
Biochemical and Biophysical Research Communications | 2002 |
Tyrosine phosphorylation-mediated signal transduction in MCP-1-induced macrophage activation: role for receptor dimerization, focal adhesion protein complex and JAK/STAT pathway
SK Biswas, A Sodhi |
International Immunopharmacology | 2002 |
The Effect of Sulfasalazine on Rheumatoid Arthritic Synovial Tissue Chemokine Production
MV Volin, PL Campbell, MA Connors, DC Woodruff, AE Koch |
Experimental and Molecular Pathology | 2002 |
Chemokines in synovial inflammation in rheumatoid arthritis: basic and clinical aspects
K Tani, T Shimizu, Y Motoki, S Sone |
Modern Rheumatology | 2002 |
CCR2 REGULATES THE LEVEL OF MCP-1/CCL2 IN VITRO AND AT INFLAMMATORY SITES AND CONTROLS T CELL ACTIVATION IN RESPONSE TO ALLOANTIGEN
LA Tylaska, L Boring, W Weng, R Aiello, IF Charo, BJ Rollins, RP Gladue |
Cytokine | 2002 |
Sensitization of IFN-γ Jak-STAT signaling during macrophage activation
X Hu, C Herrero, WP Li, TT Antoniv, E Falck-Pedersen, AE Koch, JM Woods, GK Haines, LB Ivashkiv |
Nature Immunology | 2002 |
The New Angiotherapy
TP Fan, EC Kohn |
2002 | |
Monocyte Chemoattractant Protein-1 Selectively Inhibits the Acquisition of CD40 Ligand-Dependent IL-12-Producing Capacity of Monocyte-Derived Dendritic Cells and Modulates Th1 Immune Response
N Omata, M Yasutomi, A Yamada, H Iwasaki, M Mayumi, Y Ohshima |
Journal of immunology (Baltimore, Md. : 1950) | 2002 |
The Importance of IL-1β and TNF-α, and the Noninvolvement of IL-6, in the Development of Monoclonal Antibody-Induced Arthritis
T Kagari, H Doi, T Shimozato |
Journal of immunology (Baltimore, Md. : 1950) | 2002 |
Lymphoid chemokine B cell-attracting chemokine-1 (CXCL13) is expressed in germinal center of ectopic lymphoid follicles within the synovium of chronic arthritis patients
K Shi, K Hayashida, M Kaneko, J Hashimoto, T Tomita, PE Lipsky, H Yoshikawa, T Ochi |
Journal of immunology (Baltimore, Md. : 1950) | 2001 |
Effects of intraarticular glucocorticoids on macrophage infiltration and mediators of joint damage in osteoarthritis synovial membranes: Findings in a double-blind, placebo-controlled study
L Young, A Katrib, C Cuello, U Vollmer-Conna, JV Bertouch, PJ Roberts-Thomson, MJ Ahern, MD Smith, PP Youssef |
Arthritis & Rheumatism | 2001 |
Involvement of chemokine receptor 2 and its ligand, monocyte chemoattractant protein-1, in the development of atherosclerosis: lessons from knockout mice
W Peters, IF Charo |
Current Opinion in Lipidology | 2001 |
Regulation of Nitric Oxide Production by Murine Peritoneal Macrophages Treated in Vitro with Chemokine Monocyte Chemoattractant Protein 1
SK Biswas, A Sodhi, S Paul |
Nitric Oxide | 2001 |
The role of C-C chemokines and their receptors in osteoarthritis
GH Yuan, K Masuko-Hongo, M Sakata, JI Tsuruha, H Onuma, H Nakamura, H Aoki, T Kato, K Nishioka |
Arthritis & Rheumatism | 2001 |
Monocyte chemotactic protein-1, -2, and -3 are distinctively expressed in portal tracts and granulomata in primary biliary cirrhosis: implications for pathogenesis
K Tsuneyama, K Harada, M Yasoshima, K Hiramatsu, CR Mackay, IR Mackay, ME Gershwin, Y Nakanuma |
The Journal of Pathology | 2001 |
CXCR3 and CCR5 Ligands in Rheumatoid Arthritis Synovium
DD Patel, JP Zachariah, LP Whichard |
Clinical Immunology | 2001 |
Selective lymphocyte chemokine receptor expression in the rheumatoid joint
JH Ruth, JB Rottman, KJ Katschke, S Qin, L Wu, G LaRosa, P Ponath, RM Pope, AE Koch |
Arthritis & Rheumatism | 2001 |
Chemokines and angiogenesis
Z Szekanecz, AE Koch |
Current Opinion in Rheumatology | 2001 |
Surface expression of CC- and CXC-chemokine receptors on leucocyte subsets in inflammatory joint diseases
H Brühl, K Wagner, H Kellner, M Schattenkirchner, D Schlöndorff, M Mack |
Clinical & Experimental Immunology | 2001 |
The pan-chemokine inhibitor NR58-3.14.3 abolishes tumour necrosis factor-alpha accumulation and leucocyte recruitment induced by lipopolysaccharide in vivo
J Reckless, LM Tatalick, DJ Grainger |
Immunology | 2001 |
Multimerization of monocyte chemoattractant protein-1 is not required for glycosaminoglycan-dependent transendothelial chemotaxis
S Ali, AC Palmer, SJ Fritchley, Y Maley, JA Kirby |
Biochemical Journal | 2001 |
PATHOGENESIS OF RHEUMATOID ARTHRITIS
Z Zhang, SL Bridges |
Rheumatic Disease Clinics of North America | 2001 |
Dynamic changes in cytokine levels in serum and synovial fluid following filtration leukocytapheresis therapy in patients with rheumatoid arthritis
T Hidaka, K Suzuki, M Kawakami, M Okada, K Kataharada, T Shinohara, M Takamizawa-Matsumoto, F Ohsuzu |
Journal of Clinical Apheresis | 2001 |
Overexpression of monocyte chemoattractant protein 1 in systemic sclerosis: Role of platelet-derived growth factor and effects on monocyte chemotaxis and collagen synthesis
O Distler, T Pap, O Kowal-Bielecka, R Meyringer, S Guiducci, M Landthaler, J Sch�lmerich, BA Michel, RE Gay, M Matucci-Cerinic, S Gay, U M�ller-Ladner |
Arthritis & Rheumatism | 2001 |
Identification of New Regulatory Sequences Far Upstream of the Mouse Monocyte Chemoattractant Protein-1 Gene
K Wagner, U Dendorfer, S Chilla, D Schlöndorff, B Luckow |
Genomics | 2001 |
Expression of chemokines and matrix metalloproteinases in early rheumatoid arthritis
A Katrib, PP Tak, JV Bertouch, C Cuello, HP McNeil, TJ Smeets, MC Kraan, PP Youssef |
Rheumatology (Oxford, England) | 2001 |
Soluble E-selectin Induces Monocyte Chemotaxis through Src Family Tyrosine Kinases
P Kumar, S Hosaka, AE Koch |
The Journal of biological chemistry | 2001 |
Serum Level of Macrophage Migration Inhibitory Factor as a Useful Parameter of Clinical Course in Patients with Wegener's Granulomatosis and Relapsing Polychondritis
R Ohwatari, Y Inuyama, S Fukuda, K Onoé, K Iwabuchi, J Nishihira |
The Annals of otology, rhinology, and laryngology | 2001 |
Enhancing Effect of IL-1, IL-17, and TNF-α on Macrophage Inflammatory Protein-3α Production in Rheumatoid Arthritis: Regulation by Soluble Receptors and Th2 Cytokines
M Chabaud, G Page, P Miossec |
Journal of immunology (Baltimore, Md. : 1950) | 2001 |
Synovial stromal cells from rheumatoid arthritis patients attract monocytes by producing MCP-1 and IL-8
K Hayashida, T Nanki, H Girschick, S Yavuz, T Ochi, PE Lipsky |
Arthritis Research & Therapy | 2001 |
MCP-1 promoter polymorphism in Spanish patients with systemic lupus erythematosus: MCP-1 promoter polymorphism and SLE
F Aguilar, MF González-Escribano, J Sánchez-Román, A Núñez-Roldán |
Tissue Antigens | 2001 |
Chemokines Regulate IL-6 and IL-8 Production by Fibroblast-Like Synoviocytes from Patients with Rheumatoid Arthritis
T Nanki, K Nagasaka, K Hayashida, Y Saita, N Miyasaka |
Journal of immunology (Baltimore, Md. : 1950) | 2001 |
Paracrine interactions of chondrocytes and macrophages in cartilage degradation: articular chondrocytes provide factors that activate macrophage-derived pro-gelatinase B (pro-MMP-9)
R Dreier, S Wallace, S Fuchs, P Bruckner, S Grässel |
Journal of cell science | 2001 |
Chemokine Receptor Antagonists
R Horuk, HP Ng |
Medicinal Research Reviews | 2000 |
DIFFERENTIAL INDUCTION OF JE/MCP-1 IN SUBCLONES FROM A MURINE MACROPHAGE CELL LINE, RAW 264.7: ROLE OF κB-3 BINDING PROTEIN
M Ueno |
Cytokine | 2000 |
REGULATION OF TNF-α EXPRESSION IN NORMAL MACROPHAGES: THE ROLE OF C/EBPβ
R Pope, S Mungre, H Liu, B Thimmapaya |
Cytokine | 2000 |
The pathogenesis and prevention of joint damage in rheumatoid arthritis: Advances from synovial biopsy and tissue analysis
PP Tak, B Bresnihan |
Arthritis & Rheumatism | 2000 |
Expression and production of the long pentraxin PTX3 in rheumatoid arthritis (RA)
MM Luchetti, G Piccinini, A Mantovani, G Peri, C Matteucci, G Pomponio, M Fratini, P Fraticelli, P Sambo, CD Loreto, A Doni, M Introna, A Gabrielli |
Clinical & Experimental Immunology | 2000 |
The development of clinical signs of rheumatoid synovial inflammation is associated with increased synthesis of the chemokine CXCL8 (interleukin-8)
MC Kraan, DD Patel, JJ Haringman, MD Smith, H Weedon, MJ Ahern, FC Breedveld, PP Tak |
Arthritis research | 2000 |
Bcl-2 expression in synovial fibroblasts is essential for maintaining mitochondrial homeostasis and cell viability
H Perlman, C Georganas, LJ Pagliari, AE Koch, KH 3rd, RM Pope |
Journal of immunology (Baltimore, Md. : 1950) | 2000 |
Effect of macrophage depletion on immune effector mechanisms during corneal allograft rejection in rats
WA Kuziel, SJ Morgan, TC Dawson, S Griffin, O Smithies, K Ley, N Maeda |
Investigative ophthalmology & visual science | 2000 |
Human endothelial cells express CCR2 and respond to MCP-1: direct role of MCP-1 in angiogenesis and tumor progression
R Salcedo, ML Ponce, HA Young, K Wasserman, JM Ward, HK Kleinman, JJ Oppenheim, WJ Murphy |
Blood | 2000 |
Expression of monocyte chemoattractant protein 1 in pig-to-primate cardiac xenografts
T Zhang, J Suzuki, M Kawauchi, H Nakano, H Kuroda, N Koide, H Kitahara, K Ohta, Y Wada, K Tsukioka, K Takayama, M Endoh, S Takamoto, M Isobe, J Amano |
Transplantation Proceedings | 2000 |
Identification of the Binding Site for a Novel Class of CCR2b Chemokine Receptor Antagonists: BINDING TO A COMMON CHEMOKINE RECEPTOR MOTIF WITHIN THE HELICAL BUNDLE
T Mirzadegan, F Diehl, B Ebi, S Bhakta, I Polsky, D McCarley, M Mulkins, GS Weatherhead, JM Lapierre, J Dankwardt, D Morgans, R Wilhelm, K Jarnagin |
The Journal of biological chemistry | 2000 |
Cutaneous Injection of Human Subjects with Macrophage Inflammatory Protein-1α Induces Significant Recruitment of Neutrophils and Monocytes
SC Lee, ME Brummet, S Shahabuddin, TG Woodworth, SN Georas, KM Leiferman, SC Gilman, C Stellato, RP Gladue, RP Schleimer, LA Beck |
Journal of immunology (Baltimore, Md. : 1950) | 2000 |
A Mechanism for the Impaired IFN-γ Production in C-C Chemokine Receptor 2 (CCR2) Knockout Mice: Role of CCR2 in Linking the Innate and Adaptive Immune Responses
W Peters, M Dupuis, IF Charo |
Journal of immunology (Baltimore, Md. : 1950) | 2000 |
Gelenkpathologie
W Mohr |
2000 | |
Regulation of IL-6 and IL-8 Expression in Rheumatoid Arthritis Synovial Fibroblasts: the Dominant Role for NF-κB But Not C/EBPβ or c-Jun
C Georganas, H Liu, H Perlman, A Hoffmann, B Thimmapaya, RM Pope |
Journal of immunology (Baltimore, Md. : 1950) | 2000 |
Macrophage Inflammatory Protein-2 and KC Induce Chemokine Production by Mouse Astrocytes
Y Luo, FR Fischer, WW Hancock, ME Dorf |
Journal of immunology (Baltimore, Md. : 1950) | 2000 |
Reduction of Inflammatory Cytokines and Prostaglandin E 2 by IL-13 Gene Therapy in Rheumatoid Arthritis Synovium
JM Woods, KJ Katschke, M Tokuhira, H Kurata, KI Arai, PL Campbell, AE Koch |
Journal of immunology (Baltimore, Md. : 1950) | 2000 |
Synovial fluid neutrophil expression of interleukin-8 in rheumatoid arthritis
T Kasama, H Iwabuchi, R Hanaoka, HT Takeuchi, Y Miwa, L Jing, Y Mori, K Kobayashi, M Negishi, H Ide, M Adachi |
Japanese Journal of Rheumatology | 1999 |
C/EBPβ in Rheumatoid Arthritis: Correlation with Inflammation, Not Disease Specificity1
RM Pope, R Lovis, S Mungre, H Perlman, AE Koch, GK Haines |
Clinical Immunology | 1999 |
On the edge: the physiological and pathophysiological role of chemokines during inflammatory and immunological responses
ME DeVries, L Ran, DJ Kelvin |
Seminars in Immunology | 1999 |
The MCP/eotaxin subfamily of CC chemokines
EV Coillie, JV Damme, G Opdenakker |
Cytokine & Growth Factor Reviews | 1999 |
Current perspectives on synovitis
PP Tak, FC Breedveld |
Arthritis research | 1999 |
Augmented production of chemokines (monocyte chemotactic protein-1 (MCP-1), macrophage inflammatory protein-1alpha (MIP-1alpha) and MIP-1beta) in patients with systemic sclerosis: MCP-1 and MIP-1alpha may be involved in the development of pulmonary fibrosis
M Hasegawa, S Sato, K Takehara |
Clinical & Experimental Immunology | 1999 |
Macrophage inflammatory protein 1 alpha expression by synovial fluid neutrophils in rheumatoid arthritis
Y Hatano, T Kasama, H Iwabuchi, R Hanaoka, HT Takeuchi, L Jing, Y Mori, K Kobayashi, M Negishi, H Ide, M Adachi |
Annals of the rheumatic diseases | 1999 |
Identification of oligopeptide sequences which inhibit migration induced by a wide range of chemokines
J Reckless, DJ Grainger |
Biochemical Journal | 1999 |
Effect of C-C chemokine receptor 2 (CCR2) knockout on type-2 (schistosomal antigen-elicited) pulmonary granuloma formation: analysis of cellular recruitment and cytokine responses
KS Warmington, L Boring, JH Ruth, J Sonstein, CM Hogaboam, JL Curtis, SL Kunkel, IR Charo, SW Chensue |
The American Journal of Pathology | 1999 |
The Participation of IL-8 in the Synovial Lesions at an Early Stage of Rheumatoid Arthritis
Y Takahashi, T Kasahara, T Sawai, A Rikimaru, N Mukaida, K Matsushima, T Sasaki |
The Tohoku Journal of Experimental Medicine | 1999 |
CD154 (CD40L) Induces Human Endothelial Cell Chemokine Production and Migration of Leukocyte Subsets
U Thienel, J Loike, MJ Yellin |
Cellular Immunology | 1999 |
A Novel Polymorphism in the MCP-1 Gene Regulatory Region That Influences MCP-1 Expression
BH Rovin, L Lu, R Saxena |
Biochemical and Biophysical Research Communications | 1999 |
Liposome encapsulated aurothiomalate reduces collagen-induced arthritis in DBA/1J mice
P Konigsberg |
Biochimica et Biophysica Acta (BBA) - Biomembranes | 1999 |
Chemokines: extracellular messengers for all occasions?
LM Gale, SR McColl |
BioEssays | 1999 |
Semiquantitation of human chemokine mRNA levels with a newly constructed multispecific competitor fragment
FL Dumoulin, M Altfeld, JK Rockstroh, L Leifeld, T Sauerbruch, U Spengler |
Journal of Immunological Methods | 1999 |
Flow cytometric analysis of intracellular chemokines in chondrocytes in vivo: constitutive expression and enhancement in osteoarthritis and rheumatoid arthritis
RM Borzı̀, I Mazzetti, S Macor, T Silvestri, A Bassi, L Cattini, A Facchini |
FEBS Letters | 1999 |
Decreased expression and activity of G-protein-coupled receptor kinases in peripheral blood mononuclear cells of patients with rheumatoid arthritis
MS Lombardi, A Kavelaars, M Schedlowski, JW Bijlsma, KL Okihara, MV de Pol, S Ochsmann, C Pawlak, RE Schmidt, CJ Heijnen |
The FASEB Journal | 1999 |
Regional differences on production of chemokines in gastric mucosa between Helicobacter pylori-positive duodenal ulcer and gastric ulcer
Y Sato, K Sugimura, T Mochizuki, T Honma, H Suriki, K Tashiro, K Ishizuka, R Narisawa, T Ichida, DH van Thiel, H Asakura |
Digestive Diseases and Sciences | 1999 |
Chemokines in Rheumatoid Arthritis
A Koch |
Arthritis research | 1999 |
TGF-Beta Downmodulates Cytokine-Induced Monocyte Chemoattractant Protein (MCP)-1 Expression in Human Endothelial Cells. A Putative Role for TGF-Beta in the Modulation of TNF Receptor Expression
JM Weiss, CA Cuff, JW Berman |
Endothelium : journal of endothelial cell research | 1999 |
Treatment with sulfasalazine or sulfapyridine, but not 5-aminosalicylic acid, inhibits basic fibroblast growth factor-induced endothelial cell chemotaxis
MV Volin, LA Harlow, JM Woods, PL Campbell, MA Amin, M Tokuhira, AE Koch |
Arthritis & Rheumatism | 1999 |
Effects of reactive oxygen and nitrogen metabolites on MCP-1-induced monocyte chemotactic activity in vitro
E Sato, KL Simpson, MB Grisham, S Koyama, RA Robbins |
American journal of physiology. Lung cellular and molecular physiology | 1999 |
Cloning and Functional Characterization of the 5′-Flanking Region of the Human Monocyte Chemoattractant Protein-1 Receptor (CCR2) Gene: ESSENTIAL ROLE OF 5′-UNTRANSLATED REGION IN TISSUE-SPECIFIC EXPRESSION
K Yamamoto, H Takeshima, K Hamada, M Nakao, T Kino, T Nishi, M Kochi, JI Kuratsu, T Yoshimura, Y Ushio |
The Journal of biological chemistry | 1999 |
Chemokines in Disease
CA Hébert |
1999 | |
Expression of the monocyte chemoattractant protein-1 receptor CCR2 is increased in hypercholesterolemia: differential effects of plasma lipoproteins on monocyte function
KH Han, KO Han, SR Green, O Quehenberger |
Journal of lipid research | 1999 |
Antigen-presenting cells in rheumatoid arthritis
R Thomas |
Springer Seminars in Immunopathology | 1998 |
The central role of chemokines (chemotactic cytokines) in the immunopathogenesis of ulcerative colitis and Crohn's disease
RP MacDermott, IR Sanderson, HC Reinecker |
Inflammatory Bowel Diseases | 1998 |
Quantitative microscopic analysis of inflammation in rheumatoid arthritis synovial membrane samples selected at arthroscopy compared with samples obtained blindly by needle biopsy
PP Youssef, M Kraan, F Breedveld, B Bresnihan, N Cassidy, G Cunnane, P Emery, O Fitzgerald, D Kane, S Lindblad, R Reece, D Veale, PP Tak |
Arthritis & Rheumatism | 1998 |
Abnormalities in monocyte recruitment and cytokine expression in monocyte chemoattractant protein 1-deficient mice
B Lu, BJ Rutledge, L Gu, J Fiorillo, NW Lukacs, SL Kunkel, R North, C Gerard, BJ Rollins |
Journal of Experimental Medicine | 1998 |
Simultaneous Elevation of the Levels of Circulating Monocyte Chemoattractant Protein-1 and Tissue Factor in Acute Coronary Syndromes
K Nishiyama, H Ogawa, H Yasue, H Soejima, K Misumi, K Takazoe, M Yoshimura, K Kugiyama, I Tsuji, K Kumeda |
Japanese Circulation Journal | 1998 |
Mapping of MCP-1 functional domains by peptide analysis and site-directed mutagenesis
SA Steitz, K Hasegawa, SL Chiang, RR Cobb, MA Castro, TJ Lobl, M Yamada, E Lazarides, PM Cardarelli |
FEBS Letters | 1998 |
The Central Role of Chemokines (Chemotactic Cytokines) in the Immunopathogenesis of Ulcerative Colitis and Crohnʼs Disease:
RP MacDermott, IR Sanderson, HC Reinecker |
Inflammatory Bowel Diseases | 1998 |
RANTES expression and contribution to monocyte chemotaxis in arthritis
M V Volin, M R Shah, M Tokuhira, G K Haines, J M Woods, A E Koch |
Clinical Immunology and Immunopathology | 1998 |
Lysine 58 and Histidine 66 at the C-terminal α-Helix of Monocyte Chemoattractant Protein-1 Are Essential for Glycosaminoglycan Binding
L Chakravarty, L Rogers, T Quach, S Breckenridge, PE Kolattukudy |
The Journal of biological chemistry | 1998 |
The CC Chemokine Monocyte Chemotactic Peptide-1 Activates both the Class I p85/p110 Phosphatidylinositol 3-Kinase and the Class II PI3K-C2α
SJ Turner, J Domin, MD Waterfield, SG Ward, J Westwick |
The Journal of biological chemistry | 1998 |
Role of pro-inflammatory cytokines in rheumatoid arthritis
FM Brennan, RN Maini, M Feldmann |
Springer Seminars in Immunopathology | 1998 |
The monocyte chemotactic protein a (MCP-1) and interleukin 8 (IL-8) in Hodgkin's disease and in solid tumours
MG Luciani, A Stoppacciaro, G Peri, A Mantovani, LP Ruco |
Molecular Pathology | 1998 |
Cytokines in Rheumatoid Arthritis: Potential Targets for Pharmacological Intervention
Z Szekanecz, AE Koch, SL Kunkel, RM Strieter |
Drugs & Aging | 1998 |
Chemokines in rheumatoid arthritis.
Szekanecz Z, Strieter RM, Kunkel SL, Koch AE |
Springer Seminars in Immunopathology | 1998 |
Functional CD40 ligand is expressed by T cells in rheumatoid arthritis
KP MacDonald, Y Nishioka, PE Lipsky, R Thomas |
Journal of Clinical Investigation | 1997 |
Lymphocytic airway infiltration as a precursor to fibrous obliteration in a rat model of bronchiolitis obliterans
L Boring, J Gosling, SW Chensue, SL Kunkel, RV Farese, HE Broxmeyer, IF Charo |
Journal of Clinical Investigation | 1997 |
Mononuclear phagocytes and rheumatoid synovitis. Mastermind or workhorse in arthritis?
GR Burmester, B Stuhlmüller, G Keyszer, RW Kinne |
Arthritis & Rheumatism | 1997 |
THE ROLE OF MONOCYTE CHEMOATTRACTANT PROTEIN-1 (MCP-1) IN THE PATHOGENESIS OF COLLAGEN-INDUCED ARTHRITIS IN RATS
H Ogata, M Takeya, T Yoshimura, K Takagi, K Takahashi |
The Journal of Pathology | 1997 |
Cytokines and prostaglandins in immune homeostasis and tissue destruction in periodontal disease
E Gemmell, RI Marshall, GJ Seymour |
Periodontology 2000 | 1997 |
Monocyte recruitment in cryoglobulinemic membranoproliferative glomerulonephritis: A pathogenetic role for monocyte chemotactic peptide-1
L Gesualdo, G Grandaliano, E Ranieri, R Monno, V Montinaro, C Manno, FP Schena |
Kidney International | 1997 |
Oncostatin M stimulates monocyte chemoattractant protein-1- and interleukin-1-induced matrix metalloproteinase-1 production by human synovial fibroblasts in vitro
C Langdon, J Leith, CD Richards, F Smith |
Arthritis & Rheumatism | 1997 |
An antagonist of monocyte chemoattractant protein 1 (MCP-1) inhibits arthritis in the MRL-lpr mouse model
JH Gong, LG Ratkay, JD Waterfield, I Clark-Lewis |
Journal of Experimental Medicine | 1997 |
Hyaluronan fragments induce nitric-oxide synthase in murine macrophages through a nuclear factor kappaB-dependent mechanism
CM McKee, CJ Lowenstein, MR Horton, J Wu, C Bao, BY Chin, AM Choi, PW Noble |
The Journal of biological chemistry | 1997 |
Lymphocytic airway infiltration as a precursor to fibrous obliteration in a rat model of bronchiolitis obliterans
L Boring, J Gosling, SW Chensue, SL Kunkel, RV Farese, HE Broxmeyer, IF Charo |
Transplantation | 1997 |
Low-Level Production of Interleukin-13 in Synovial Fluid and Tissue from Patients with Arthritis
JM Woods, GK Haines, MR Shah, G Rayan, AE Koch |
Clinical Immunology and Immunopathology | 1997 |
MONOCYTE CHEMOTACTIC PEPTIDE-1 EXPRESSION AND MONOCYTE INFILTRATION IN ACUTE RENAL TRANSPLANT REJECTION1:
G Grandaliano, L Gesualdo, E Ranieri, R Monno, G Stallone, FP Schena |
Transplantation | 1997 |
Target effector role of vascular endothelium in the inflammatory response: insights from the clinical trial of anti-TNF alpha antibody in rheumatoid arthritis
E Paleolog |
Molecular Pathology | 1997 |
Progress in Drug Research/Fortschritte der Arzneimittelforschung/Progrès des recherches pharmaceutiques
RM Eglen, MR Juchau, G Edwards, AH Weston, H Wise, MD Murray, DC Brater, O Valdenaire, P Vernier, A Polak, E Jucker |
1997 | |
Interleukin-15 (IL-15) Induces IL-8 and Monocyte Chemotactic Protein 1 Production in Human Monocytes
R Badolato, AN Ponzi, M Millesimo, LD Notarangelo, T Musso |
Blood | 1997 |
Activation of human monocytes for enhanced production of interleukin 8 during transendothelial migration in vitro
M Takahashi, U Ikeda, T Kasahara, S Kitagawa, Y Takahashi, K Shimada, S Kano, C Morimoto, J Masuyama |
Journal of Clinical Immunology | 1997 |
Cytokine and nitric oxide production in the acute phase of bacterial cell wall-induced arthritis
J W Fuseler, E M Conner, J M Davis, R E Wolf, M B Grisham |
Inflammation | 1997 |
Severe reduction in leukocyte adhesion and monocyte extravasation in mice deficient in CC chemokine receptor 2.
Kuziel WA, Morgan SJ, Dawson TC, Griffin S, Smithies O, Ley K, Maeda N |
Proceedings of the National Academy of Sciences | 1997 |
Hyaluronan (HA) fragments induce chemokine gene expression in alveolar macrophages. The role of HA size and CD44
CM McKee, MB Penno, M Cowman, MD Burdick, RM Strieter, C Bao, PW Noble |
Journal of Clinical Investigation | 1996 |
Alterations of the mucosal immune system in inflammatory bowel disease
RP MacDermoit |
Journal of Gastroenterology | 1996 |
Role of cytokines, acute-phase proteins, and chemokinesin the progression of rheumatoid arthritis
R Badolato, JJ Oppenheim |
Seminars in Arthritis and Rheumatism | 1996 |
ROLE OF CYTOKINES IN RHEUMATOID ARTHRITIS
M Feldmann, FM Brennan, RN Maini |
Annual Review of Immunology | 1996 |
Opposite effects of interleukin-13 and interleukin-12 on the release of inflammatory cytokines, cytokine inhibitors and prostaglandin E from synovial fibroblasts and blood mononuclear cells
M Seitz, P Loetscher, B Dewald, H Towbin, M Baggiolini |
European Journal of Immunology | 1996 |
Chemokines: a superfamily of chemotactic cytokines
S Sozzani, M Locati, P Allavena, J Damme, A Mantovani |
International Journal of Clinical & Laboratory Research | 1996 |
Hepatocyte growth factor. A cytokine mediating endothelial migration in inflammatory arthritis
AE Koch, MM Halloran, S Hosaka, MR Shah, CJ Haskell, SK Baker, RJ Panos, GK Haines, GL Bennett, RM Pope, N Ferrara |
Arthritis & Rheumatism | 1996 |
Monocyte chemoattractant protein-1 levels in patients with glomerular disease
BH Rovin, N Doe, LC Tan |
American Journal of Kidney Diseases | 1996 |
Monocyte chemoattractant protein-1 gene expression in prostatic hyperplasia and prostate adenocarcinoma
L Mazzucchelli, P Loetscher, A Kappeler, M Uguccioni, M Baggiolini, JA Laissue, C Mueller |
The American Journal of Pathology | 1996 |
Differential effects of protein kinase C inhibitors on chemokine production in human synovial fibroblasts
NJ Jordan, ML Watson, T Yoshimura, J Westwick |
British Journal of Pharmacology | 1996 |
Inhibition of T cell recruitment and cutaneous delayed-type hypersensitivity-induced inflammation with antibodies to monocyte chemoattractant protein-1
ML Rand, JS Warren, MK Mansour, W Newman, DJ Ringler |
The American Journal of Pathology | 1996 |
Protective antibody therapy is associated with reduced chemokine transcripts in herpes simplex virus type 1 corneal infection
YH Su, XT Yan, JE Oakes, RN Lausch |
Journal of virology | 1996 |
HCC-1, a novel chemokine from human plasma
P Schulz-Knappe, HJ Mägert, B Dewald, M Meyer, Y Cetin, M Kubbies, J Tomeczkowski, K Kirchhoff, M Raida, K Adermann, A Kist, M Reinecke, R Sillard, A Pardigol, M Uguccioni, M Baggiolini, WG Forssmann |
Journal of Experimental Medicine | 1996 |
The intratracheal administration of endotoxin: X. Dexamethasone downregulates neutrophil emigration and cytokine expression in vivo
ES Yi, DG Remick, Y Lim, W Tang, CE Nadzienko, A Bedoya, S Yin, TR Ulich |
Inflammation | 1996 |
The Chemokine Superfamily: Crosstalk with the IL-1 System
A Mantovani, M Locati, P Allavena, S Sozzani |
Immunobiology | 1996 |
Essentials of Mucosal Immunology
DK Podolsky |
Essentials of Mucosal Immunology | 1996 |
Expression of monocyte chemoattractant protein-1 mRNA and protein in cultured human thyrocytes
K Kasai, N Banba, S Motohashi, Y Hattori, K Manaka, SI Shimoda |
FEBS Letters | 1996 |
Monocyte chemoattractant protein 1: a potential regulator of monocyte recruitment in inflammatory disease
BJ Rollins |
Molecular Medicine Today | 1996 |
Cloning and functional expression of mCCR2, a murine receptor for the C-C chemokines JE and FIC
T Kurihara, R Bravo |
The Journal of biological chemistry | 1996 |
Molecular Cloning and Functional Expression of Murine JE (Monocyte Chemoattractant Protein 1) and Murine Macrophage Inflammatory Protein 1 Receptors: EVIDENCE FOR TWO CLOSELY LINKED C-C CHEMOKINE RECEPTORS ON CHROMOSOME 9
L Boring, J Gosling, FS Monteclaro, AJ Lusis, CL Tsou, IF Charo |
The Journal of biological chemistry | 1996 |
Interleukin-10 expression and chemokine regulation during the evolution of murine type II collagen-induced arthritis
T Kasama, RM Strieter, NW Lukacs, PM Lincoln, MD Burdick, SL Kunkel |
Journal of Clinical Investigation | 1995 |
Role of Macrophage-Like Synovial Lining Cells in Localization and Expression of Experimental Arthritis
PL van Lent, AE Holthuysen, L Bersselaar, N Rooijen, LB van de Putte, WB van Berg |
Scandinavian Journal of Rheumatology | 1995 |
Chemokine expression in rheumatoid arthritis (RA): evidence of RANTES and macrophage inflammatory protein (MIP)-1β production by synovial T cells
E Robinson, EC Keystone, TJ Schall, N Gillett, EN Fish |
Clinical & Experimental Immunology | 1995 |
Identification of MIP-1α/LD78 as a Monocyte Chemoattractant Released by the HTLV-I-Transformed Cell Line MT4
R Bertini, W Luini, S Sozzani, B Bottazzi, P Ruggiero, D Boraschi, D Saggioro, L Chieco-Bianchi, P Proost, JV Damme, A Mantovani |
AIDS Research and Human Retroviruses | 1995 |
Monocyte-chemoattractant protein 1 gene expression in intestinal epithelial cells and inflammatory bowel disease mucosa
HC Reinecker, EY Loh, DJ Ringler, A Mehta, JL Rombeau, RP MacDermott |
Gastroenterology | 1995 |
Production of monocyte chemoattractant protein-1 by bovine glomerular endothelial cells
Y Kakizaki, S Waga, K Sugimoto, H Tanaka, K Nukii, M Takeya, T Yoshimura, M Yokoyama |
Kidney International | 1995 |
Keratinocyte-Derived Monocyte Chemoattractant Protein 1 (MCP-1): Analysis in a Transgenic Model Demonstrates MCP-1 Can Recruit Dendritic and Langerhans Cells to Skin
K Nakamura, IR Williams, TS Kupper |
Journal of Investigative Dermatology | 1995 |
Induction of human monocyte motility by lysyl oxidase
HM Lazarus, WW Cruikshank, N Narasimhan, HM Kagan, DM Center |
Matrix Biology | 1995 |
Expression of a Human Mutant Monocyte Chemotactic Protein 3 inPichia pastorisand Characterization as an MCP-3 Receptor Antagonist
S Masure, L Paemen, P Proost, JV Damme, G Opdenakker |
Journal of Interferon & Cytokine Research | 1995 |
Modulation of JE/MCP-1 expression in dermal wound repair
LA DiPietro, PJ Polverini, SM Rahbe, EJ Kovacs |
The American Journal of Pathology | 1995 |
Chemokine expression in rheumatoid arthritis (RA): evidence of RANTES and macrophage inflammatory protein (MIP)-1 beta production by synovial T cells
E Robinson, EC Keystone, TJ Schall, N Gillett, EN Fish |
Clinical & Experimental Immunology | 1995 |
The effect of a synthetic 7-thiaprostaglandin E1 derivative, TEI-6122, on monocyte chemoattractant protein-1 induced chemotaxis in THP-1 cells
H Tanaka, T Minoshima, N Endo |
British Journal of Pharmacology | 1995 |
Regulatory roles of tumor necrosis factor-alpha and interleukin-1 beta in monocyte chemoattractant protein-1-mediated pulmonary granuloma formation in the rat
CM Flory, ML Jones, BF Miller, JS Warren |
The American Journal of Pathology | 1995 |
Antagonists of monocyte chemoattractant protein 1 identified by modification of functionally critical NH2-terminal residues
JH Gong, I Clark-Lewis |
Journal of Experimental Medicine | 1995 |
A dominant negative inhibitor indicates that monocyte chemoattractant protein 1 functions as a dimer
Y Zhang, BJ Rollins |
Molecular and cellular biology | 1995 |
Porphyromonas gingivalis lipopolysaccharide is poorly recognized by molecular components of innate host defense in a mouse model of early inflammation
RA Reife, RA Shapiro, BA Bamber, KK Berry, GE Mick, RP Darveau |
Infection and immunity | 1995 |
The protein phosphatase inhibitor calyculin A stimulates chemokine production by human synovial cells
NJ Jordan, ML Watson, J Westwick |
Biochemical Journal | 1995 |
Tumor necrosis factor α and transforming growth factor β upregulate astrocyte expression of monocyte chemoattractant protein-1
AA Hurwitz, WD Lyman, JW Herman |
Journal of Neuroimmunology | 1995 |
Chemokines of the α, β-subclass inhibit human basophils' responsiveness to monocyte chemotactic and activating factor/monocyte chemoattractant protein-1
P Kuna, SR Reddigari, D Rucinskia, TJ Schall, AP Kaplan |
Journal of Allergy and Clinical Immunology | 1995 |
Immunopharmacology of Free Radical Species
C Rice-Evans |
Immunopharmacology of Free Radical Species | 1995 |
The role of monocyte chemotactic protein-1 (MCP-1) in the recruitment of monocytes and CD4+ T cells during a pulmonary Cryptococcus neoformans infection
IF Charo, SJ Myers, A Herman, C Franci, AJ Connolly, SR Coughlin |
Journal of immunology (Baltimore, Md. : 1950) | 1995 |
Neutrophil-macrophage Interaction: a paradigm for chronic inflammation
DL Lefkowitz, K Mills, SS Lefkowitz, A Bollen, N Moguilevsky |
Medical Hypotheses | 1995 |
Suppressive Role of Endogenous Endothelial Monocyte Chemoattractant Protein–1 on Monocyte Transendothelial Migration In Vitro
M Takahashi, JI Masuyama, U Ikeda, SI Kitagawa, T Kasahara, M Saito, S Kano, K Shimada |
Arteriosclerosis, thrombosis, and vascular biology | 1995 |
Effects of Th1 and Th2 cytokines on cytokine production and ICAM-1 expression on synovial fibroblasts
JF Schlaak, A Schwarting, P Knolle, KH zum Buschenfelde, W Mayet |
Annals of the rheumatic diseases | 1995 |
Macrophage inflammatory protein-1 alpha. A novel chemotactic cytokine for macrophages in rheumatoid arthritis
AE Koch, SL Kunkel, LA Harlow, DD Mazarakis, GK Haines, MD Burdick, RM Pope, RM Strieter |
Journal of Clinical Investigation | 1994 |
Epithelial neutrophil activating peptide-78: a novel chemotactic cytokine for neutrophils in arthritis
AE Koch, SL Kunkel, LA Harlow, DD Mazarakis, GK Haines, MD Burdick, RM Pope, A Walz, RM Strieter |
Journal of Clinical Investigation | 1994 |
C/EBP beta regulation of the tumor necrosis factor alpha gene
RM Pope, A Leutz, SA Ness |
Journal of Clinical Investigation | 1994 |
Monocyte chemoattractant protein 1 and interleukin 8 production by rheumatoid synoviocytes. Effects of anti-rheumatic drugs
P Loetscher, B Dewald, M Baggiolini, M Seitz |
Cytokine | 1994 |
Detection of monocyte chemotactic and activating factor (MCAF) in normal blood and urine using a sensitive ELISA
N Ida, S Sakurai, G Kawano |
Cytokine | 1994 |
Interferon-gamma Stimulates Monocyte Chemotactic Protein-1 Expression by Monocytes
JM Liebler, SL Kunkel, RM Allen, MD Burdick, RM Strieter |
Mediators of Inflammation | 1994 |
Monocyte chemoattractant protein 1 acts as a T-lymphocyte chemoattractant
MW Carr, SJ Roth, E Luther, SS Rose, TA Springer |
Proceedings of the National Academy of Sciences | 1994 |
Monocyte chemoattractant protein-1 in idiopathic pulmonary fibrosis and other interstitial lung diseases
K Iyonaga, M Takeya, N Saita, O Sakamoto, T Yoshimura, M Ando, K Takahashi |
Human Pathology | 1994 |
The role of tumour necrosis factor-alpha and IL-1 in polymorphonuclear leucocyte and T lymphocyte recruitment to joint inflammation in adjuvant arthritis
A Issekutz, A Meager, I Otterness, T Issekutz |
Clinical & Experimental Immunology | 1994 |
A new monoclonal antibody (5D3-F7) which recognizes human monocyte-chemotactic protein-1 but not related chemokines. Development of a sandwich ELISA and in situ detection of producing cells
G Peri, C Milanese, C Matteucci, L Ruco, Z Dan, S Silvano, C Isabella, M Alberto |
Journal of Immunological Methods | 1994 |
Interleukin-8 and Related Chemotactic Cytokines
M Baggiolini, B Moser, I Clark-Lewis |
Chest | 1994 |
Functional role of the cis-acting elements in human monocyte chemotactic protein-1 gene in the regulation of its expression by phorbol ester in human glioblastoma cells
YS Li, PE Kolattukudy |
Molecular and Cellular Biochemistry | 1994 |
Molecular cloning and functional expression of two monocyte chemoattractant protein 1 receptors reveals alternative splicing of the carboxyl-terminal tails.
Charo IF, Myers SJ, Herman A, Franci C, Connolly AJ, Coughlin SR |
Proceedings of the National Academy of Sciences | 1994 |
The Molecular and Cellular Biology of Wound Repair
RA Clark, PM Henson |
1988 |