In this study we examined the leukocytic oxidant species that induce oxidant damage of DNA in whole cells. H2O2 added extracellularly in micromolar concentrations (10-100 microM) induced DNA strand breaks in various target cells. The sensitivity of a specific target cell was inversely correlated to its catalase content and the rate of removal of H2O2 by the target cell. Oxidant species produced by xanthine oxidase/purine or phorbol myristate acetate-stimulated monocytes induced DNA breakage of target cells in proportion to the amount of H2O2 generated. These DNA strand breaks were prevented by extracellular catalase, but not by superoxide dismutase. Cytotoxic doses of HOCl, added to target cells, did not induce DNA strand breakage, and myeloperoxidase added extracellularly in the presence of an H2O2-generating system, prevented the formation of DNA strand breaks in proportion to its H2O2 degrading capacity. The studies also indicated that H2O2 formed hydroxyl radical (.OH) intracellularly, which appeared to be the most likely free radical responsible for DNA damage: .OH was detected in cells exposed to H2O2; the DNA base, deoxyguanosine, was hydroxylated in cells exposed to H2O2; and intracellular iron was essential for induction of DNA strand breaks.
I Schraufstätter, P A Hyslop, J H Jackson, C G Cochrane
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Hepatoprotective effects of Niudali (Callerya speciosa) root aqueous extracts against tetrachloromethane-induced acute liver injury and inflammation.
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Food Science & Nutrition | 2023 |
The Relationship between Cancer and Paraoxonase 1
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Antioxidants | 2022 |
Herb and Spices in Colorectal Cancer Prevention and Treatment: A Narrative Review.
Hossain MS, Kader MA, Goh KW, Islam M, Khan MS, Harun-Ar Rashid M, Ooi J, Melo Coutinho HD, Al-Worafi YM, Moshawih S, Lim YC, Kibria KMK, Ming LC |
Frontiers in pharmacology | 2022 |
Novel NRF2-activated cancer treatments utilizing synthetic lethality.
Baird L, Kensler TW, Yamamoto M |
IUBMB Life | 2022 |
Role of Endolysosome Function in Iron Metabolism and Brain Carcinogenesis
PW Halcrow, ML Lynch, JD Geiger, JE Ohm |
Seminars in Cancer Biology | 2021 |
Effects of cranberry beverages on oxidative stress and gut microbiota in subjects with Helicobacter pylori infection: a randomized, double-blind, placebo-controlled trial
T Gao, M Hou, B Zhang, X Pan, C Liu, C Sun, M Jia, S Lin, K Xiong, A Ma |
Food & Function | 2021 |
A protective effect of curcumin on cardiovascular oxidative stress indicators in systemic inflammation induced by lipopolysaccharide in rats
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Biochemistry and Biophysics Reports | 2021 |
Gastroprotective effects of extract of Jasminum grandiflorum L. flower in HCl/EtOH-induced gastric mucosal ulceration mice
Y Zhang, L Sun, X Lai, X Peng, S Wen, Z Zhang, Y Xie, Q Li, R Chen, , K Zhang, S Sun, D Li |
Biomedicine & pharmacotherapy = Biomédecine & pharmacothérapie | 2021 |
Role of the Neutrophil in the Pathogenesis of Advanced Cancer and Impaired Responsiveness to Therapy
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Molecules (Basel, Switzerland) | 2020 |
Mitochondria Autoimmunity and MNRR1 in Breast Carcinogenesis: A Review.
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Journal of cancer immunology | 2020 |
Highly stable and biocompatible hyaluronic acid-rehabilitated nanoscale MOF-Fe 2+ induced ferroptosis in breast cancer cells
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Journal of Materials Chemistry B | 2020 |
Preventative and Therapeutic Potential of Flavonoids in Peptic Ulcers
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Molecules (Basel, Switzerland) | 2020 |
Therapeutic efficacy of the root tubers of Aconitum heterophyllum and its substitute Cyperus rotundus in the amelioration of pylorus ligation induced ulcerogenic and oxidative damage in rats
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Saudi Journal of Biological Sciences | 2020 |
Occupational Cancers
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Chemical composition, antioxidant, anti-inflammatory, and cytotoxic activities of Opuntia stricta cladodes
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Lycopene Inhibits Reactive Oxygen Species-Mediated NF-κB Signaling and Induces Apoptosis in Pancreatic Cancer Cells
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Nutrients | 2019 |
Muscle Injury in the Athlete: The Italian Consensus Conference Guidelines
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2019 | |
Oxidative-protective effects of Tinospora cordifolia extract on plasma and spleen cells after experimental ochratoxicosis
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Comparative Clinical Pathology | 2018 |
Molecular and Therapeutic actions of Thymoquinone
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2018 | |
Genotoxic impact of long-term cigarette and waterpipe smoking on DNA damage and oxidative stress in healthy subjects
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Toxicology Mechanisms and Methods | 2018 |
Nuclear complex of glyceraldehyde-3-phosphate dehydrogenase and DNA repair enzyme apurinic/apyrimidinic endonuclease I protect smooth muscle cells against oxidant-induced cell death
X Hou, P Snarski, Y Higashi, T Yoshida, A Jurkevich, P Delafontaine, S Sukhanov |
The FASEB Journal | 2017 |
Do all roads lead to the Rome? The glycation perspective!
S Ahmad, F Akhter, U Shahab, Z Rafi, MS Khan, R Nabi, MS Khan, K Ahmad, JM Ashraf, Moinuddin |
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Improved antioxidative and cytotoxic activities of chamomile (Matricaria chamomilla) florets fermented by Lactobacillus plantarum KCCM 11613P
EH Park, WY Bae, SJ Eom, KT Kim, HD Paik |
Journal of Zhejiang University SCIENCE B | 2017 |
A HClO-specific near-infrared fluorescent probe for determination of Myeloperoxidase activity and imaging mitochondrial HClO in living cells
F Tian, Y Jia, Y Zhang, W Song, G Zhao, Z Qu, C Li, Y Chen, P Li |
Biosensors and Bioelectronics | 2016 |
Oral magnesium reduces gastric mucosa susceptibility to injury in experimental diabetes mellitus
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Pathophysiology | 2016 |
Biomarkers in Disease: Methods, Discoveries and Applications
JD Johnston, WD Burnett, SA Kontulainen |
Biomarkers in Disease: Methods, Discoveries and Applications | 2016 |
Novel aspects of pathogenesis and regeneration mechanisms in COPD
R Aldonyte, E Bagdonas, J Raudoniute, I Bruzauskaite |
International journal of chronic obstructive pulmonary disease | 2015 |
Handbook on the Toxicology of Metals
A Elder, GF Nordberg, M Kleinman |
Handbook on the Toxicology of Metals | 2015 |
Antioxidative Activity of Onion Peel Extract in Obese Women: A Randomized, Double-blind, Placebo Controlled Study
KA Kim, JE Yim |
Journal of Cancer Prevention | 2015 |
High intake of heterocyclic amines from meat is associated with oxidative stress
AM Carvalho, AM Miranda, FA Santos, AP Loureiro, RM Fisberg, DM Marchioni |
British Journal of Nutrition | 2015 |
Tumour, Oxidative Stress and Host T Cell Response: Cementing the Dominance
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Scandinavian Journal of Immunology | 2015 |
Neurodegenerative changes and apoptosis induced by intrauterine and extrauterine exposure of radiofrequency radiation
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Journal of Chemical Neuroanatomy | 2015 |
Antioxidative and Anticanceric Activities of Magnolia (Magnolia denudata) Flower Petal Extract Fermented by Pediococcus acidilactici KCCM 11614
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Molecules (Basel, Switzerland) | 2015 |
Curcumin, Inflammation, and Chronic Diseases: How Are They Linked?
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Molecules (Basel, Switzerland) | 2015 |
Serum Anti-carbonic Anhydrase Antibodies and Oxidant–Antioxidant Balance in Patients with Acute Anterior Uveitis
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Ocular Immunology and Inflammation | 2014 |
Cytotoxic and antioxidant properties of active principals isolated from water hyacinth against four cancer cells lines
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BMC complementary and alternative medicine | 2014 |
General Methods in Biomarker Research and their Applications
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General Methods in Biomarker Research and their Applications | 2014 |
Molecular pathways: reactive oxygen species homeostasis in cancer cells and implications for cancer therapy
V Nogueira, N Hay |
Clinical cancer research | 2013 |
Prooxidant mechanisms in iron overload cardiomyopathy
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BioMed Research International | 2013 |
Effects of 2-amino-1-methyl-6-phenylimidazo [4, 5-b] pyridine (PhIP) on histopathology, oxidative stress, and expression of c-fos, c-jun and p16 in rat stomachs
R Li, J Tian, W Li, J Xie |
Food and Chemical Toxicology | 2013 |
Ischemia-modified albumin: could it be a new oxidative stress biomarker for colorectal carcinoma?
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Gut and Liver | 2013 |
Methods in Enzymology
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Protein Engineering for Therapeutics Part B | 2012 |
Investigation of in vitro and in vivo antioxidant potential of secoisolariciresinol diglucoside
SS Moree, J Rajesha |
Molecular and Cellular Biochemistry | 2012 |
Vulnerability of Gastric Mucosa in Diabetic Rats, Its Pathogenesis and Amelioration by Cuminum cyminum
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Indian journal of pharmaceutical sciences | 2012 |
Molecular, Clinical and Environmental Toxicology
A Luch |
2012 | |
Oxidative Stress and Disease
I Paur, M Carlsen, B Halvorsen, R Blomhoff |
Herbal Medicine | 2011 |
Limited DNA damage in human endothelial cells after hyperbaric oxygen treatment and protection from subsequent hydrogen peroxide exposure
J Yuan, RD Handy, AJ Moody, G Smerdon, P Bryson |
Biochimica et Biophysica Acta (BBA) - General Subjects | 2011 |
Comparative gastroprotective effect of post-treatment with low doses of rutin and cimetidine in rats: Gastroprotective property of rutin and cimetidine
MT Olaleye, AC Akinmoladun |
Fundamental & Clinical Pharmacology | 2011 |
Inhibitory effect of carboxymethylpachymaran on cyclophosphamide-induced oxidative stress in mice
XJ Wei, TJ Hu, JR Chen, YY Wei |
International Journal of Biological Macromolecules | 2011 |
Bioengineering Aspects in the Design of Gas Exchangers
JN Maina |
2011 | |
Oxidative stress, inflammation, and cancer: How are they linked?
S Reuter, SC Gupta, MM Chaturvedi, BB Aggarwal |
Free radical biology & medicine | 2010 |
DNA damage and its relationship with other oxidative stress parameters in Behcet’s disease
ED Sezer, K Aksu, O Caglayan, G Keser, G Karabulut, G Ercan |
Rheumatology International | 2010 |
Mitochondrial dysfunction may explain the cardiomyopathy of chronic iron overload
X Gao, M Qian, JL Campian, J Marshall, Z Zhou, AM Roberts, YJ Kang, SD Prabhu, XF Sun, JW Eaton |
Free radical biology & medicine | 2010 |
Effects of maternal hyperhomocysteinemia induced by methionine intake on oxidative stress and apoptosis in pup rat brain
ST Koz, NT Gouwy, N Demir, VS Nedzvetsky, E Etem, G Baydas |
International Journal of Developmental Neuroscience | 2010 |
Cellular and Molecular Biology of Metals
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Cellular and Molecular Biology of Metals | 2010 |
β-Carotene metabolites enhance inflammation-induced oxidative DNA damage in lung epithelial cells
YG van Helden, J Keijer, AM Knaapen, SG Heil, JJ Briedé, FJ van Schooten, RW Godschalk |
Free radical biology & medicine | 2009 |
Lysosomes in iron metabolism, ageing and apoptosis
T Kurz, A Terman, B Gustafsson, UT Brunk |
Histochemistry and Cell Biology | 2008 |
Hydrogen Peroxide and Wound Healing: A Theoretical and Practical Review for Hair Transplant Surgeons
S Wasserbauer, D Perez-Meza, R Chao |
Dermatologic Surgery | 2008 |
Inflammation and Lung Cancer: Roles of Reactive Oxygen/Nitrogen Species
N Azad, Y Rojanasakul, V Vallyathan |
Journal of Toxicology and Environmental Health, Part B | 2008 |
The involvement of lysosomes in myocardial aging and disease
A Terman, T Kurz, B Gustafsson, UT Brunk |
Current cardiology reviews | 2008 |
Lysosomes and oxidative stress in aging and apoptosis
T Kurz, A Terman, B Gustafsson, UT Brunk |
Biochimica et Biophysica Acta (BBA) - General Subjects | 2008 |
Mitochondrial DNA Damage in Iron Overload
X Gao, JL Campian, M Qian, XF Sun, JW Eaton |
The Journal of biological chemistry | 2008 |
Reactive Oxygen Species Regulate Hypoxia-Inducible Factor 1α Differentially in Cancer and Ischemia
AA Qutub, AS Popel |
Molecular and cellular biology | 2008 |
Etanercept reduces the oxidative stress marker levels in patients with rheumatoid arthritis
Y Kageyama, M Takahashi, T Nagafusa, E Torikai, A Nagano |
Rheumatology International | 2007 |
Antiapoptotic and immunomodulatory effects of chlorophyllin
D Sharma, SS Kumar, KB Sainis |
Molecular Immunology | 2007 |
Pathophysiological aspects of cyclophosphamide and ifosfamide induced hemorrhagic cystitis; implication of reactive oxygen and nitrogen species as well as PARP activation
A Korkmaz, T Topal, S Oter |
Cell Biology and Toxicology | 2007 |
Melatonin inhibits oxidative stress and apoptosis in fetal brains of hyperhomocysteinemic rat dams
G Baydas, ST Koz, M Tuzcu, E Etem, VS Nedzvetsky |
Journal of Pineal Research | 2007 |
Methotrexate reduces the levels of pentosidine and 8-hydroxy-deoxy guanosine in patients with rheumatoid arthritis
Y Kageyama, M Takahashi, T Nagafusa, E Torikai, A Nagano |
Modern Rheumatology | 2007 |
Antioxidant activities of Sophora subprosrate polysaccharide in immunosuppressed mice
J Chen, T Hu, R Zheng |
International Immunopharmacology | 2007 |
Effect of PJ-34 PARP-Inhibitor on Rat Liver Microcirculation and Antioxidant Status
A Szijártó, E Batmunkh, O Hahn, Z Mihály, A Kreiss, A Kiss, G Lotz, Z Schaff, L Váli, A Blázovics, D Geró, C Szabó, P Kupcsulik |
Journal of Surgical Research | 2007 |
Autophagy, ageing and apoptosis: The role of oxidative stress and lysosomal iron
T Kurz, A Terman, UT Brunk |
Archives of Biochemistry and Biophysics | 2007 |
Handbook of Neurochemistry and Molecular Neurobiology
VH Routh, JJ McArdle, NM Sanders, Z Song, R Wang |
Handbook of Neurochemistry and Molecular Neurobiology | 2007 |
Cytotoxic and mutagenic effects of tobacco-borne free fatty acids
X Gao, M Qian, JL Campian, DR Clark, TJ Burke, JW Eaton, WG McGregor |
Free radical biology & medicine | 2006 |
Effects of Aspirin on the Pathogenesis of Acute Lung Injury in Rats Subjected to Hemorrhage
Y Park, YM Lee |
Tuberculosis and Respiratory Diseases | 2006 |
Hsp70 expression and free radical release after exposure to non-thermal radio-frequency electromagnetic fields and ultrafine particles in human Mono Mac 6 cells
M Simkó, C Hartwig, M Lantow, M Lupke, MO Mattsson, Q Rahman, J Rollwitz |
Toxicology Letters | 2006 |
Molecular targets against mustard toxicity: implication of cell surface receptors, peroxynitrite production, and PARP activation
A Korkmaz, H Yaren, T Topal, S Oter |
Archives of Toxicology | 2006 |
Free Radical Release and HSP70 Expression in Two Human Immune-Relevant Cell Lines after Exposure to 1800 MHz Radiofrequency Radiation
M Lantow, J Schuderer, C Hartwig, M Simkó |
Radiation Research | 2006 |
Poly(ADP-ribose) polymerase activation by reactive nitrogen species—Relevance for the pathogenesis of inflammation
C Szabó |
Nitric Oxide | 2006 |
Inflammation and cancer: How hot is the link?
BB Aggarwal, S Shishodia, SK Sandur, MK Pandey, G Sethi |
Biochemical Pharmacology | 2006 |
Lysosomal labilization
A Terman, T Kurz, B Gustafsson, U Brunk |
IUBMB Life | 2006 |
Immunostimulating activities of the novel peptidomimetic L-glutamyl-histamine
MA Babizhayev, YA Semiletov, YA Lul'kin, NL Sakina, EL Savel'yeva, LM Alimbarova, IP Barinskii |
Clinical & Experimental Immunology | 2005 |
The crucial role of particle surface reactivity in respirable quartz-induced reactive oxygen/nitrogen species formation and APE/Ref-1 induction in rat lung
C Albrecht, AM Knaapen, A Becker, D Höhr, P Haberzettl, FJ van Schooten, PJ Borm, RP Schins |
Respiratory Research | 2005 |
3D molecular modeling, free radical modulating and immune cells signaling activities of the novel peptidomimetic l-glutamyl-histamine: possible immunostimulating role
MA Babizhayev, YA Semiletov, YA Lul’kin, NL Sakina, EL Savel’yeva, LM Alimbarova, IP Barinskii |
Peptides | 2005 |
Reduction of Bone Nodule Formation in MC3T3-E1 Cells by Treatment with Hydrogen Peroxide
Y Otsuka-Tanaka, T Sato, T Fujita, H Suzuki, M Kawara, Y Abiko, J Mega |
International Journal of Oral-Medical Sciences | 2005 |
Nitrite enhances neutrophil-induced DNA strand breakage in pulmonary epithelial cells by inhibition of myeloperoxidase
AM Knaapen, RP Schins, PJ Borm, FJ van Schooten |
Carcinogenesis | 2005 |
The protective effect of l-carnitine in peripheral blood human lymphocytes exposed to oxidative agents
CL Garcia, S Filippi, P Mosesso, M Calvani, R Nicolai, L Mosconi, F Palitti |
Mutagenesis | 2005 |
Inhaled particles and lung cancer. Part A: Mechanisms
AM Knaapen, PJ Borm, C Albrecht, RP Schins |
International Journal of Cancer | 2004 |
In vitro genotoxicity assessment of commercial quartz flours in comparison to standard DQ12 quartz
GD Cakmak, RP Schins, T Shi, I Fenoglio, B Fubini, PJ Borm |
International Journal of Hygiene and Environmental Health | 2004 |
Molecular Neurotoxicology: Environmental Agents and Transcription-Transduction Coupling
T Stedeford, F Cardozo-Pelaez |
Molecular Neurotoxicology: Environmental Agents and Transcription-Transduction Coupling | 2004 |
Nitric Oxide Inhibition of Homocysteine-induced Human Endothelial Cell Apoptosis by Down-regulation of p53-dependent Noxa Expression through the Formation of S -Nitrosohomocysteine
SJ Lee, KM Kim, S Namkoong, CK Kim, YC Kang, H Lee, KS Ha, JA Han, HT Chung, YG Kwon, YM Kim |
The Journal of biological chemistry | 2004 |
Myeloperoxidase-derived Hypochlorous Acid Antagonizes the Oxidative Stress-mediated Activation of Iron Regulatory Protein 1
S Mütze, U Hebling, W Stremmel, J Wang, J Arnhold, K Pantopoulos, S Mueller |
The Journal of biological chemistry | 2003 |
Eosinophil peroxidase catalyzes JNK-mediated membrane blebbing in a Rho kinase-dependent manner
B McElhinney, ME Poynter, P Shrivastava, SL Hazen, YM Janssen-Heininger |
Journal of leukocyte biology | 2003 |
Asbestos-Induced Pulmonary Toxicity: Role of DNA Damage and Apoptosis
D Upadhyay, DW Kamp |
Experimental biology and medicine (Maywood, N.J.) | 2003 |
Role of poly(ADP-ribose) synthetase in pulmonary leukocyte recruitment
R Kiefmann, K Heckel, M Dörger, S Schenkat, M Stoeckelhuber, J Węsierska-Gądek, AE Goetz |
American journal of physiology. Lung cellular and molecular physiology | 2003 |
Hydrogen Peroxide Signaling through Tumor Necrosis Factor Receptor 1 Leads to Selective Activation of c-Jun N-terminal Kinase
C Pantano, P Shrivastava, B McElhinney, Y Janssen-Heininger |
The Journal of biological chemistry | 2003 |
Atherosclerosis, Hypertension and Diabetes
GN Pierce, M Nagano, P Zahradka, NS Dhalla |
2003 | |
Antitumor Agents 4. Characterization of Free Radicals Produced during Reduction of the Antitumor Drug 5 H -Pyridophenoxazin-5-one: An EPR Study
A Alberti, A Bolognese, M Guerra, A Lavecchia, D Macciantelli, M Marcaccio, E Novellino, F Paolucci |
Biochemistry | 2003 |
Mechanism of Ascididemin-Induced Cytotoxicity
SS Matsumoto, J Biggs, BR Copp, JA Holden, LR Barrows |
Chemical Research in Toxicology | 2003 |
Asthmatic bronchial epithelium is more susceptible to oxidant-induced apoptosis
F Bucchieri, SM Puddicombe, JL Lordan, A Richter, D Buchanan, SJ Wilson, J Ward, G Zummo, PH Howarth, R Djukanović, ST Holgate, DE Davies |
American journal of respiratory cell and molecular biology | 2002 |
Molecular bases of cellular iron toxicity12 1Guest Editor: Mario Comporti 2This article is part of a series of reviews on “Iron and Cellular Redox Status.” The full list of papers may be found on the homepage of the journal
JW Eaton, M Qian |
Free radical biology & medicine | 2002 |
Detection of DNA single-strand breaks and glutathione in mononuclear blood cells of radiotherapy technicians
A Akköse, B Ömer, G Deniz, E Darendeliler |
Addiction Biology | 2002 |
Syk Is Required for p38 Activation and G2/M Arrest in B Cells Exposed to Oxidative Stress
J He, T Takano, J Ding, S Gao, C Noda, K Sada, S Yanagi, H Yamamura |
Antioxidants & Redox Signaling | 2002 |
Hydrogen peroxide-induced apoptosis of HL-60 human leukemia cells is mediated by the oxidants hypochlorous acid and chloramines
BA Wagner, BE Britigan, KJ Reszka, ML McCormick, CP Burns |
Archives of Biochemistry and Biophysics | 2002 |
Pro-oxidant and cytotoxic effects of circulating heme
V Jeney, J Balla, A Yachie, Z Varga, GM Vercellotti, JW Eaton, G Balla |
Blood | 2002 |
Oxidant-induced DNA damage by quartz in alveolar epithelial cells
RP Schins, AM Knaapen, GD Cakmak, T Shi, C Weishaupt, PJ Borm |
Mutation Research/Genetic Toxicology and Environmental Mutagenesis | 2002 |
A Novel Peroxide-induced Calcium Transient Regulates Interleukin-6 Expression in Cardiac-derived Fibroblasts
JT Colston, B Chandrasekar, GL Freeman |
The Journal of biological chemistry | 2002 |
Physiological Concentrations of (−)-Epigallocatechin-3-O-Gallate (EGCg) Prevent Chromosomal Damage Induced by Reactive Oxygen Species in WIL2-NS Cells
A Sugisawa, K Umegaki |
The Journal of nutrition | 2002 |
Oxygen/Nitrogen Radicals: Cell Injury and Disease
V Vallyathan, X Shi, V Castranova |
2002 | |
Type II Guanine Oxidation Photoinduced by the Antibacterial Fluoroquinolone Rufloxacin in Isolated DNA and in 2‘-Deoxyguanosine
A Belvedere, F Boscá, A Catalfo, MC Cuquerella, G de Guidi, MA Miranda |
Chemical Research in Toxicology | 2002 |
Mechanisms of neutrophil-induced DNA damage in respiratory tract epithelial cells
Ad M Knaapen, Roel P F Schins, Dünya Polat, Andrea Becker, Paul J A Borm |
Molecular and Cellular Biochemistry | 2002 |
Effect of overexpression of human Cu/Zn-SOD on activation-induced lymphocyte proliferation and apoptosis
MA Pahlavani, JF Mele, A Richardson |
Free radical biology & medicine | 2001 |
l-Tyrosine and nitric oxide synergize to prevent cytotoxic effects of superoxide
AC Souici, AL Fitzhugh, LK Keefer, E Felley-Bosco |
Toxicology | 2001 |
Reactive oxygen species mediate alpha-adrenergic receptor-stimulated hypertrophy in adult rat ventricular myocytes
JK Amin, L Xiao, DR Pimental, PJ Pagano, K Singh, DB Sawyer, WS Colucci |
Journal of Molecular and Cellular Cardiology | 2001 |
Inflammatory and Infectious Basis of Atherosclerosis
JL Mehta |
2001 | |
Induction of Chromosomal Aberrations and Growth-Transformation of Lymphoblastoid Cell Lines by Inhibition of Reactive Oxygen Species-Induced Apoptosis with Interleukin-6
H Miwa, H Kanno, S Munakata, Y Akano, M Taniwaki, K Aozasa |
Laboratory Investigation | 2000 |
DNA endonuclease- and active oxygen-associated degradation of chloroplast DNA in response to paraquat-induced oxidative stress
JH Kim, SH Shin, SH Cho, WS Lee |
Journal of Plant Biology | 2000 |
Mechanism of protection by the flavonoids, quercetin and rutin, against tert-butylhydroperoxide- and menadione-induced DNA single strand breaks in Caco-2 cells
SA Aherne, NM O’Brien |
Free radical biology & medicine | 2000 |
Response of human oral epithelial cells to oxidative damage and the effect of vitamin E
G Royack |
Oral Oncology | 2000 |
The effect of vitamin C or vitamin E supplementation on basal and H2O2-induced DNA damage in human lymphocytes
LA Brennan, GM Morris, GR Wasson, BM Hannigan, YA Barnett |
British Journal of Nutrition | 2000 |
Initiation of Rapid, P53-Dependent Growth Arrest in Cultured Human Skin Fibroblasts by Reactive Chlorine Species
GF Vile, LA Rothwell, AJ Kettle |
Archives of Biochemistry and Biophysics | 2000 |
Analysis of DNA oxidative damage related to cell proliferation
P Villani, PL Altavista, L Castaldi, G Leter, E Cordelli |
Mutation Research/Genetic Toxicology and Environmental Mutagenesis | 2000 |
The Redox State and Circadian Rhythms
TV Driessche, JL Guisset, GM Vries |
2000 | |
Neutrophils cause oxidative DNA damage in alveolar epithelial cells
AM Knaapen, F Seiler, PA Schilderman, P Nehls, J Bruch, RP Schins, PJ Borm |
Free radical biology & medicine | 1999 |
Hypochlorous acid causes caspase activation and apoptosis or growth arrest in human endothelial cells
MC Vissers, JM Pullar, MB Hampton |
Biochemical Journal | 1999 |
Oxidative DNA Damage Induced by Aminoacetone, an Amino Acid Metabolite
Y Hiraku, J Sugimoto, T Yamaguchi, S Kawanishi |
Archives of Biochemistry and Biophysics | 1999 |
OXIDATIVE STRESS AND PULMONARY INFLAMMATION: PHARMACOLOGICAL INTERVENTION WITH ANTIOXIDANTS
EJ Morcillo, J Estrela, J Cortijo |
Pharmacological Research | 1999 |
Presence of Bleomycin-Detectable Free Iron in the Alveolar System of Preterm Infants
CE Gerber, G Bruchelt, H Stegmann, F Schweinsberg, CP Speer |
Biochemical and Biophysical Research Communications | 1999 |
Loss of GSH and thiol enzymes in endothelial cells exposed to sublethal concentrations of hypochlorous acid
JM Pullar, CC Winterbourn, MC Vissers |
American journal of physiology. Heart and circulatory physiology | 1999 |
Inflammatory cell-mediated tumour progression and minisatellite mutation correlate with the decrease of antioxidative enzymes in murine fibrosarcoma cells
F Okada, K Nakai, T Kobayashi, T Shibata, S Tagami, Y Kawakami, T Kitazawa, R Kominami, S Yoshimura, K Suzuki, N Taniguchi, O Inanami, M Kuwabara, H Kishida, D Nakae, Y Konishi, T Moriuchi, M Hosokawa |
British Journal of Cancer | 1999 |
Eicosanoids and Other Bioactive Lipids in Cancer, Inflammation, and Radiation Injury, 4
KV Honn, LJ Marnett, S Nigam, EA Dennis |
1999 | |
Biologic Effects of Light 1998
MF Holick, EG Jung |
1999 | |
Environmental Metal Pollutants, Reactive Oxygen Intermediaries and Genotoxicity
ME Ariza, GN Bijur, MV Williams |
1999 | |
Report From The Conference On Ultrasound-Assisted Liposuction Safety And Effects
VL Young, MW Schorr |
Clinics in Plastic Surgery | 1999 |
Effect of in vitro generation of oxygen free radicals on T cell function in young and old rats
MA Pahlavani, MD Harris |
Free radical biology & medicine | 1998 |
Reactive oxygen species activity and lipid peroxidation in Helicobacter pylori associated gastritis: relation to gastric mucosal ascorbic acid concentrations and effect of H pylori eradication
IM Drake, NP Mapstone, CJ Schorah, KL White, DM Chalmers, MF Dixon, AT Axon |
Gut | 1998 |
Role of poly(ADP-ribose)synthetase in inflammation
C Szabó |
European Journal of Pharmacology | 1998 |
Hypochlorous Acid Activates the Tumor Suppressor Protein p53 in Cultured Human Skin Fibroblasts
GF Vile, LA Rothwell, AJ Kettle |
Archives of Biochemistry and Biophysics | 1998 |
F2-isoprostane generation in isolated ferret lungs after oxidant injury or ventilated ischemia
P M Becker, S P Sanders, P Price, B W Christman |
Free radical biology & medicine | 1998 |
Free Radicals, Oxidative Stress, and Antioxidants
T Özben |
1998 | |
Critical Care Nephrology
C Ronco, R Bellomo |
1998 | |
Levels of DNA strand breaks and superoxide in phorbol ester-treated human granulocytes
HC Birnboim, JK Sandhu |
Journal of Cellular Biochemistry | 1997 |
Alterations in intracellular reactive oxygen species generation and redox potential modulate mast cell function
K Wolfreys, DB Oliveira |
European Journal of Immunology | 1997 |
Apoptotic vs. Nonapoptotic Cytotoxicity Induced by Hydrogen Peroxide
AM Gardner, F Xu, C Fady, FJ Jacoby, DC Duffey, Y Tu, A Lichtenstein |
Free radical biology & medicine | 1997 |
Effects of chloride channel blockers on hypoxic injury in rat proximal tubules
WB Reeves |
Kidney International | 1997 |
Overexpression of superoxide dismutase and catalase in immortalized neural cells: toxic effects of hydrogen peroxide
H Mann, MT McCoy, J Subramaniam, HV Remmen, JL Cadet |
Brain Research | 1997 |
Modulation of cisPlatin cytotoxicity by interleukin-1α and resident tumor macrophages
PG Braunschweiger, VS Basrur, D Cameron, L Sharpe, O Santos, JP Perras, BU Sevin, AM Markoe |
Biotherapy | 1997 |
Ex Vivo Induction of Apoptosis in Lymphocytes Is Mediated by Oxidative Stress: Role for Lymphocyte Loss in HIV Infection
TS Dobmeyer, S Findhammer, JM Dobmeyer, SA Klein, B Raffel, D Hoelzer, EB Helm, D Kabelitz, R Rossol |
Free radical biology & medicine | 1997 |
Immunogenicity of DNA Damaged by Reactive Oxygen Species—Implications for Anti-DNA Antibodies in Lupus
MS Cooke, N Mistry, C Wood, KE Herbert, J Lunec |
Free radical biology & medicine | 1997 |
Reinvestigation of in vivo genotoxicity studies in man. I. No induction of DNA strand breaks in peripheral lymphocytes after metronidazole therapy
R Fahrig, M Engelke |
Mutation Research/Genetic Toxicology and Environmental Mutagenesis | 1997 |
Neutrophils amplify the formation of DNA adducts by benzo[a]pyrene in lung target cells
PJ Borm, AM Knaapen, RP Schins, RW Godschalk, FJ Schooten |
Environmental Health Perspectives | 1997 |
DNA Damage Induced by Peroxynitrite: Subsequent Biological Effects
C Szabó, H Ohshima |
Nitric Oxide | 1997 |
Advances in Molecular and Cell Biology
KJ Clemetson |
Advances in Molecular and Cell Biology | 1997 |
Quercetin and myricetin protect against hydrogen peroxide-induced DNA damage (strand breaks and oxidised pyrimidines) in human lymphocytes
SJ Duthie, AR Collins, GG Duthie, VL Dobson |
Mutation Research/Genetic Toxicology and Environmental Mutagenesis | 1997 |
The induction of apoptosis in proliferating human fibroblasts by oxygen radicals is associated with a p53- and p21WAF1CIP1 induction
S Gansauge, F Gansauge, H Gause, B Poch, M H Schoenberg, H G Beger |
FEBS Letters | 1997 |
The Influence of Cell Growth, Detoxifying Enzymes and DNA Repair on Hydrogen Peroxide-Mediated DNA Damage (Measured Using the Comet Assay) in Human Cells
SJ Duthie, AR Collins |
Free radical biology & medicine | 1996 |
Review
M Epstein |
Renal Failure | 1996 |
Involvement of oxidation in LDL-induced collagen gene regulation in mesangial cells
HS Lee, BC Kim, YS Kim, KH Choi, HK Chung |
Kidney International | 1996 |
DNA strand breakage and activation of poly-ADP ribosyltransferase: A cytotoxic pathway triggered by peroxynitrite
C SzabÓ |
Free radical biology & medicine | 1996 |
Mutagenic potential of peripheral blood leukocytes: in vivo exposure to the carcinogen 7,12-dimethylbenz[a]anthracene, and the tumor promoter 12-O-tetradecanoylphorbol acetate followed by in vitro co-culture with AS52 cells
ME Ariza, AS Oberyszyn, FM Robertson, MV Williams |
Cancer Letters | 1996 |
Evidence for involvement of multiple iron species in DNA single-strand scission by H2O2 in HL-60 cells
RW Byrnes |
Free radical biology & medicine | 1996 |
DNA strand breakage, activation of poly (ADP-ribose) synthetase, and cellular energy depletion are involved in the cytotoxicity of macrophages and smooth muscle cells exposed to peroxynitrite
C Szabó, B Zingarelli, M O'Connor, AL Salzman |
Proceedings of the National Academy of Sciences | 1996 |
Research communication copper-1,10-phenanthroline induces internucleosomal DNA fragmentation in HepG2 cells, resulting from direct oxidation by the hydroxyl radical
SY Tsang, SC Tam, I Bremner, MJ Burkitt |
Biochemical Journal | 1996 |
Mobilization of iron from cellular ferritin by ascorbic acid in neuroblastoma SK-N-SH cells: an EPR study
SL Baader, E Bill, AX Trautwein, G Bruchelt, BF Matzanke |
FEBS Letters | 1996 |
Peroxynitrite formed by simultaneous generation of nitric oxide and superoxide selectively inhibits bovine aortic prostacyclin synthase
MH Zou, V Ullrich |
FEBS Letters | 1996 |
Sodium nitroprusside-induced apoptotic cellular death via production of hydrogen peroxide in murine neuroblastoma N1E-115 cells
M Yamada, K Momose, E Richelson, M Yamada |
Journal of Pharmacological and Toxicological Methods | 1996 |
Isolation and preliminary characterization of a Chinese hamster ovary cell line with high-degree resistance to hydrogen peroxide
O Cantoni, P Sestili, L Palomba, A Guidarelli, F Cattabeni, D Murray |
Biochemical Pharmacology | 1996 |
Cellular injury induced by oxidative stress is mediated through lysosomal damage
K Öllinger, UT Brunk |
Free radical biology & medicine | 1995 |
Hydrogen peroxide as a potent bacteriostatic antibiotic: Implications for host defense
PA Hyslop, DB Hinshaw, IU Scraufstatter, CG Cochrane, S Kunz, K Vosbeck |
Free radical biology & medicine | 1995 |
TWO GENES CONTRIBUTE TO DIFFERENT EXTENTS TO THE HEME OXYGENASE ENZYME ACTIVITY MEASURED IN CULTURED HUMAN SKIN FIBROBLASTS AND KERATINOCYTES: IMPLICATIONS FOR PROTECTION AGAINST OXIDANT STRESS
LA Applegate, A Noël, G Vile, E Frenk, RM Tyrrell |
Photochemistry and Photobiology | 1995 |
Toxicity of oxygen from naturally occurring redox-active pro-oxidants
RS Pardini |
Archives of Insect Biochemistry and Physiology | 1995 |
Effects of oxidative stress and Ca2+ agonists on molecular chaperones in human umbilical vein endothelial cells
D Dreher, JR Vargas, DF Hochstrasser, AF Junod |
Electrophoresis | 1995 |
The kinetics of repair of oxidative DNA damage (strand breaks and oxidised pyrimidines) in human cells
AR Collins, M Ai-guo, SJ Duthie |
Mutation Research/DNA Repair | 1995 |
DNA strand breakage and base modification induced by hydrogen peroxide treatment of human respiratory tract epithelial cells
JP Spencer, A Jenner, K Chimel, OI Aruoma, CE Cross, R Wu, B Halliwell |
FEBS Letters | 1995 |
Menadione-induced DNA fragmentation without 8-oxo-2′-deoxyguanosine formation in isolated rat hepatocytes
A Fischer-Nielsen, GB Corcoran, HE Poulsen, LM Kamendulis, S Loft |
Biochemical Pharmacology | 1995 |
Oxidative defense in cultured human skin fibroblasts and keratinocytes from sun-exposed and non-exposed skin
LA Applegate, E Frenk |
Photodermatology, Photoimmunology & Photomedicine | 1995 |
Induction of DNA recombination by activated 3-amino-1-methyl-5H-pyrido[4,3-b]indole
K Hiramoto, S Kanamitsu, K Negishi, H Ikeda, H Hayatsu |
Japanese journal of cancer research : Gann | 1995 |
Antioxidant defence mechanism of the skin against UV irradiation: Study of the role of catalase using acatalasaemia fibroblasts
Y Shindo, T Hashimoto |
Archives of Dermatological Research | 1995 |
Induction of DNA Recombination by Activated 3‐Amino‐1‐methyl‐5H‐pyrido[4,3‐b]indole
Hiramoto K, Kanamitsu S, Negishi K, Ikeda H, Hayatsu H |
Japanese journal of cancer research : Gann | 1995 |
Activation of potassium channels contributes to hypoxic injury in proximal tubules
WB Reeves, SV Shah |
Journal of Clinical Investigation | 1994 |
Cultured AIDS-related Kaposi's sarcoma cells retain a proliferative bioenergetic profile but demonstrate reduced cytoprotective capabilities
SR Mallery, CL Ng-Bautista, LE Lantry, GM Ness, AK Hegtvedt, A Lazo, RT Bailer, BL Hout, RE Stephens, GP Brierley |
Journal of Cellular Biochemistry | 1994 |
Role of active oxygen species in DNA damage by pentachlorophenol metabolites
S Naito, Y Ono, I Somiya, S Inoue, K Ito, K Yamamoto, S Kawanishi |
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis | 1994 |
Involvement of inflammatory reactions and elevated cell proliferation in the development of bladder cancer in schistosomiasis patients
MP Rosin, SS el Zaki, AJ Ward, WA Anwar |
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis | 1994 |
Decreased expression of liver glutathione peroxidase in Long-Evans cinnamon mutant rats predisposed to hepatitis and hepatoma
H Suemizu, S Yoshimura, N Takeichi, T Moriuchi |
Hepatology | 1994 |
Mechanisms of cell injury by activated oxygen species
JL Farber |
Environmental Health Perspectives | 1994 |
Potential molecular mechanisms of oxidant-induced carcinogenesis
JH Jackson |
Environmental Health Perspectives | 1994 |
Relative importance of oxidation and Ca2+ in DNA strand breakage by H2O2 in the 2sFou cell line
J Davies, JK Chipman |
Toxicology in Vitro | 1994 |
The induction/loss of the oxidant-resistant phenotype of Chinese hamster ovary (CHO) cell variants does not correlate with sensitivity to DNA single strand breakage by hydrogen peroxide
P Sestili, F Cattabeni, O Cantoni |
Biochemical Pharmacology | 1994 |
Effects of Nicotinamide and Niacin on Bleomycin-Induced Acute Injury and Subsequent Fibrosis in Hamster Lungs
A Nagai, H Matsumiya, M Hayashi, S Yasui, H Okamoto, K Konno |
Experimental Lung Research | 1994 |
8-Hydroxydeoxyguanosine in DNA from TPA-Stimulated Human Granulocytes
HC Birnboim, L Maidt, T Raynor, RA Floyd |
Free Radical Research | 1994 |
Abnormal glutathione metabolism and increased cytotoxicity caused by H2O2 in human umbilical vein endothelial cells cultured in high glucose medium
A Kashiwagi, T Asahina, M Ikebuchi, Y Tanaka, Y Takagi, Y Nishio, R Kikkawa, Y Shigeta |
Diabetologia | 1994 |
Ascorbic-acid-mediated iron release from cellular ferritin and its relation to the formation of DNA strand breaks in neuroblastoma cells
SL Baader, G Bruchelt, TC Carmine, HN Lode, AG Rieth, D Niethammer |
Journal of Cancer Research and Clinical Oncology | 1994 |
Etiopathogenesis
Y Mizuno, DB Calne, R Horowski |
1994 | |
Down-regulation of P4501A1 and P4501A2 mRNA expression in isolated hepatocytes by oxidative stress
CW Barker, JB Fagan, DS Pasco |
The Journal of biological chemistry | 1994 |
Activated murine neutrophils induce unscheduled DNA synthesis in B lymphocytes
S Janz, E Shacter |
Mutation Research/DNA Repair | 1993 |
Toxicity, single-strand breaks, and 5-hydroxymethyl-2′-deoxyuridine formation in human breast epithelial cells treated with hydrogen peroxide☆
Z Djuric, CK Everett, DA Luongo |
Free radical biology & medicine | 1993 |
Acridine orange-mediated photodamage to cultured cells
JM Zdolsek |
APMIS | 1993 |
Protection of human endothelial cells from oxidant injury by adenovirus-mediated transfer of the human catalase cDNA
SC Erzurum, P Lemarchand, MA Rosenfeld, JH Yoo, RG Crystal |
Nucleic Acids Research | 1993 |
Effect of medium pH on glutathione redox cycle in cultured human umbilical vein endothelial cells
M Ikebuchi, A Kashiwagi, T Asahina, Y Tanaka, Y Takagi, Y Nishio, H Hidaka, R Kikkawa, Y Shigeta |
Metabolism | 1993 |
A cellular model of oxidant-mediated neuronal injury
DB Hinshaw, MT Miller, GM Omann, TF Beals, PA Hyslop |
Brain Research | 1993 |
Suppression of development of anti-nuclear antibody and glomerulonephritis in NZB x NZWF1 mice by persistent infection with lactic dehydrogenase virus: possible involvement of superoxide anion as a progressive effector
T Hayashi, Y Noguchi, Y Kameyama |
International Journal of Experimental Pathology | 1993 |
Differential effect of l-histidine in human lymphocytes damaged by different oxygen radical producing systems
M Marini, F Frabetti, G Zunica, G Brandi, O Cantoni |
Mutation Research Letters | 1993 |
A sensitivity to oxidative stress is linked to chromosome 11 but is not due to a difference in single strand DNA breakage or repair
AJ Ward, PL Olive, AH Burr, MP Rosin |
Mutation Research/DNA Repair | 1993 |
Mutational specificity of oxidative DNA damage
J Retèl, B Hoebee, JE Braun, JT Lutgerink, E Akker, AH Wanamarta, H Joenje, MV Lafleur |
Mutation Research/Genetic Toxicology | 1993 |
Shock, Sepsis, and Organ Failure
G Schlag, H Redl, D Traber |
1993 | |
Oxidative Stress, Cell Activation and Viral Infection
C Pasquier, RY Olivier, C Auclair, L Packer |
1993 | |
Pathophysiology of Shock, Sepsis, and Organ Failure
G Schlag, H Redl |
1993 | |
Oxidative DNA damage and cellular sensitivity to oxidative stress in human autoimmune diseases
S Bashir, G Harris, MA Denman, DR Blake, PG Winyard |
Annals of the rheumatic diseases | 1993 |
Hydrogen peroxide induces DNA single strand breaks in respiratory epithelial cells
RJ McDonald, LC Pan, JA George, DM Hyde, JM Ducore |
Inflammation | 1993 |
Activation of endothelial cell phospholipase D by hydrogen peroxide and fatty acid hydroperoxide
V Natarajan, MM Taher, B Roehm, NL Parinandi, HH Schmid, Z Kiss, JG Garcia |
The Journal of biological chemistry | 1993 |
Endonuclease-induced DNA damage and cell death in oxidant injury to renal tubular epithelial cells
N Ueda, SV Shah |
Journal of Clinical Investigation | 1992 |
The role of free radicals in asbestos-induced diseases
DW Kamp, P Graceffa, WA Pryor, SA Weitzman |
Free radical biology & medicine | 1992 |
Cell death and lipid peroxidation in isolated hepatocytes incubated in the presence of hydrogen peroxide and iron salts
I Latour, JL Pregaldien, P Buc-Calderon |
Archives of Toxicology | 1992 |
Hypochlorous acid potentiates hydrogen peroxide-mediated DNA-strand breaks in human mononuclear leucocytes
CE Rensburg, AM Staden, R Anderson, EJ Rensburg |
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis | 1992 |
Genetic and environmental influences on baseline SCE
BA Hirsch, KK Sentz, M McGue |
Environmental and Molecular Mutagenesis | 1992 |
Nucleosomal histone protein protects DNA from iron-mediated damage
HU Enright, WJ Miller, RP Hebbel |
Nucleic Acids Research | 1992 |
Inhibition of organic anion transport in endothelial cells by hydrogen peroxide
DB Hinshaw, JM Burger, RE Delius, PA Hyslop, GM Omann |
Archives of Biochemistry and Biophysics | 1992 |
The role of thiol oxidation in cobalt(II)-induced toxicity in hamster lung
CP Lewis, M Demedts, B Nemery |
Biochemical Pharmacology | 1992 |
Effect of lipophilic chelators on oxyradical-induced DNA strand breaks in human granulocytes: Paradoxical effect of 1,10-phenanthroline
HC Birnboim |
Archives of Biochemistry and Biophysics | 1992 |
Ceruloplasmin and Transferrin Levels Are Altered in Serum and Bronchoalveolar Lavage Fluid of Patients with the Adult Respiratory Distress Syndrome
JA Krsek-Staples, RR Kew, RO Webster |
American journal of respiratory and critical care medicine | 1992 |
Biological Oxidants: Generation and Injurious Consequences
AW Segal, JH Nugent |
Biological Oxidants: Generation and Injurious Consequences | 1992 |
Repair of DNA damage induced by oxygen radicals in human non-proliferating and proliferating lymphocytes
E Kaminskas, JC Li |
Mutation Research/DNA Repair | 1992 |
Immunosuppressive effect of emodin, a free radical generator
HC Huang, JH Chang, SF Tung, RT Wu, ML Foegh, SH Chu |
European Journal of Pharmacology | 1992 |
Bleomycin-induced unscheduled DNA synthesis in non-permeabilized human and rat hepatocytes is not paralleled by 8-oxo-7,8-dihydrodeoxyguanosine formation
PG Winyard, SP Faux, AJ Smith, JE Davies, JK Chipman |
Biochemical Pharmacology | 1992 |
Ferritin: a cytoprotective antioxidant strategem of endothelium
G Balla, HS Jacob, J Balla, M Rosenberg, K Nath, F Apple, JW Eaton, GM Vercellotti |
The Journal of biological chemistry | 1992 |
Reactive oxygen molecules, oxidant injury and renal disease
SP Andreoli |
Pediatric Nephrology | 1991 |
Differential protective effects of O-phenanthroline and catalase on H2O2-induced DNA damage and inhibition of protein synthesis in endothelial cells
L Jornot, H Petersen, AF Junod |
Journal of Cellular Physiology | 1991 |
Mechanisms of oxidant injury of cells
CG Cochrane |
Molecular Aspects of Medicine | 1991 |
Methods of assessing oxidant injury in renal tubular epithelial cells in vitro
SP Andreoli, CH Mallett |
Journal of Tissue Culture Methods | 1991 |
DNA damage by oxygen-derived species Its mechanism and measurement in mammalian systems
B Halliwell, OI Aruoma |
FEBS Letters | 1991 |
Inactivation of poly(ADP-ribose) polymerase by hypochlorous acid
CE Rensburg, AM Staden, R Anderson |
Free radical biology & medicine | 1991 |
DNA strand breaks and DNA repair response in lymphocytes after chronic in vivo exposure to very low doses of ionizing radiation in mice
SJ James, SM Enger, T Makinodan |
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis | 1991 |
The measurement of DNA strand breaks in rat colonic mucosa by fluorometric analysis of DNA unwinding
AJ Percy, JK Chipman |
Toxicology Letters | 1991 |
Pro-oxidative interactions of dithranol with human phagocytes promote oxidative damage to DNA of bystander leucocytes
DM Forrester, CE Rensburg, R Anderson |
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis | 1991 |
Repeated exposures to enzyme-generated oxidants cause alveolitis, epithelial hyperplasia, and fibrosis in hamsters
JM Nakashima, JR Levin, DM Hyde, SN Giri |
The American Journal of Pathology | 1991 |
Copper-ion-dependent damage to the bases in DNA in the presence of hydrogen peroxide
OI Aruoma, B Halliwell, E Gajewski, M Dizdaroglu |
Biochemical Journal | 1991 |
Ionic and radical oxidations of DNA by hydrogen peroxide
JF Mouret, M Polverelli, F Sarrazini, J Cadet |
Chemico-Biological Interactions | 1991 |
Metabolic inhibition potentiates oxidant injury
RE Delius, DB Hinshaw |
Journal of Surgical Research | 1991 |
Inhibition of the myeloperoxidase-H2O2-Cl− system of neutrophils by indomethacin and other non-steroidal anti-inflammatory drugs
E Shacter, RL Lopez, S Pati |
Biochemical Pharmacology | 1991 |
Reactive oxygen injury to cultured pulmonary artery endothelial cells: Mediation by poly(ADP-ribose) polymerase activation causing NAD depletion and altered energy balance
RL Thies, AP Autor |
Archives of Biochemistry and Biophysics | 1991 |
Oxidative Damage & Repair
A Sevanian |
Oxidative Damage & Repair | 1991 |
DNA Strand Break Formation Following Exposure of Bovine Pulmonary Artery and Aortic Endothelial Cells to Reactive Oxygen Products
RG Spragg |
American journal of respiratory cell and molecular biology | 1991 |
Flavonoids, but not protein kinase c inhibitors, prevent stress protein synthesis during erythrophagocytosis
S Kantengwa, BS Polla |
Biochemical and Biophysical Research Communications | 1991 |
Reactive Oxygen Species Production by Monocytes and Polymorphonuclear Leukocytes During Dialysis
J Himmelfarb, JM Lazarus, R Hakim |
American Journal of Kidney Diseases | 1991 |
Purine and Pyrimidine Metabolism in Man VII
RA Harkness, GB Elion, N Zöllner |
1991 | |
Molecular Aspects of Inflammation
H Sies, L Flohé, G Zimmer |
1991 | |
Blood Cell Biochemistry Volume 3
JR Harris |
1991 | |
Eicosanoids and Other Bioactive Lipids in Cancer and Radiation Injury
KV Honn, LJ Marnett, S Nigam, TL Walden |
1991 | |
Site-specific DNA damage induced by hydrazine in the presence of manganese and copper ions. The role of hydroxyl radical and hydrogen atom
K Yamamoto, S Kawanishi |
The Journal of biological chemistry | 1991 |
Mechanisms of hypochlorite injury of target cells
IU Schraufstätter, K Browne, A Harris, PA Hyslop, JH Jackson, O Quehenberger, CG Cochrane |
Journal of Clinical Investigation | 1990 |
Oxygen radicals in lung pathology
CJ Doelman, A Bast |
Free radical biology & medicine | 1990 |
Reactive oxygen molecule-mediated injury in endothelial and renal tubular epithelial cells in vitro
SP Andreoli, JA McAteer, C Mallett |
Kidney International | 1990 |
Activation of Human Immunodeficiency Virus Type 1 by Oxidative Stress
S Legrand-Poels, D Vaira, J Pincemail, AV de Vorst, J Piette |
AIDS Research and Human Retroviruses | 1990 |
Effects of variation in glutathione peroxidase activity on DNA damage and cell survival in human cells exposed to hydrogen peroxide and t-butyl hydroperoxide
BE Sandström, SL Marklund |
Biochemical Journal | 1990 |
High Performance Liquid Chromatography-Electrochemical Assay for Monitoring the Formation of 8-Oxo-7,8-dihydroadenine and its Related 2′-Deoxyribonucleoside
M Berger, C Anselmino, JF Mouret, J Cadet |
Journal of Liquid Chromatography | 1990 |
Reoxygenation injury and antioxidant protection: A tale of two paradoxes
JM Gutteridge, B Halliwell |
Archives of Biochemistry and Biophysics | 1990 |
Protection from cellular oxidative injury and calcium intrusion by N-(2-mercaptoethyl)-1,3-propanediamine, WR 1065
BS Polla, Y Donati, M Kondo, HJ Tochon-Danguy, JP Bonjour |
Biochemical Pharmacology | 1990 |
Protection by Deferoxamine from Endothelial Injury: A Possible Link with Inhibition of Intracellular Xanthine Oxidase
JE Rinaldo, M Gorry |
American journal of respiratory cell and molecular biology | 1990 |
Mineral dust exposure and free radical-mediated lung damage
C J Doelman, R Leurs, W C Oosterom, A Bast |
Experimental Lung Research | 1990 |
Vitamin C and Cellular Immune Functions: Protection Against Hypochlorous Acid-Mediated Inactivation of Glyceraldehyde-3-Phosphate Dehydrogenase and ATP Generation in Human Leukocytes as A Pos
R Anderson, MJ Smit, GK Joone, AM van Staden |
Annals of the New York Academy of Sciences | 1990 |
Selective Degeneration of Oligodendrocytes Mediated by Reactive Oxygen Species
C Griot, M Vandevelde, A Richard, E Peterhans |
Free Radical Research | 1990 |
Peptide Growth Factors and Their Receptors II
MB Sporn, AB Roberts |
1990 | |
DNA damage induced by phorbol ester-stimulated neutrophils is augmented by extracellular cofactors. Role of histidine and metals
E Shacter, RL Lopez, EJ Beecham, S Janz |
The Journal of biological chemistry | 1990 |
Damage to the bases in DNA induced by stimulated human neutrophils
JH Jackson, E Gajewski, IU Schraufstatter, PA Hyslop, AF Fuciarelli, CG Cochrane, M Dizdaroglu |
Journal of Clinical Investigation | 1989 |
Differential effects of hyperoxia and hydrogen peroxide on DNA damage, polyadenosine diphosphate-ribose polymerase activity, and nicotinamide adenine dinucleotide and adenosine triphosphate contents in cultured endothelial cells and fibroblasts
AF Junod, L Jornot, H Petersen |
Journal of Cellular Physiology | 1989 |
Differential lymphocyte growth-modifying effects of oxidants: Changes in cytosolic Ca+2
DD Duncan, DA Lawrence |
Toxicology and Applied Pharmacology | 1989 |
Tobacco-borne siderophoric activity
M Qian, JW Eaton |
Archives of Biochemistry and Biophysics | 1989 |
Cytotoxic Effects of 6-Hydroxydopamine, Merocyanine-540 and Related Compounds on Human Neuroblastoma-and Hematopoietic Stem Cells
G Bruchelt, G Grygar, J Treuner, H Esterbauer, D Niethammer |
Free Radical Research | 1989 |
Oxygen free radicals, inflammation, and synovitis: and synovitis: the current status
P Merry, PG Winyard, CJ Morris, M Grootveld, DR Blake |
Annals of the rheumatic diseases | 1989 |
Stimulation of Collagen Gene Expression by Ascorbic Acid in Cultured Human Fibroblasts
M Chojkier, K Houglum, J Solis-Herruzo, DA Brenner |
The Journal of biological chemistry | 1989 |
Dynamics of the Diradylglycerol Responses of Stimulated Phagocytes
RW Dougherty, GR Dubay, JE Niedel |
The Journal of biological chemistry | 1989 |
Iron Ion-dependent Modification of Bases in DNA by the Superoxide Radical-generating System Hypoxanthine/Xanthine Oxidase
OI Aruoma, B Halliwell, M Dizdaroglu |
The Journal of biological chemistry | 1989 |