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Platelet-activating factor mediates hemodynamic changes and lung injury in endotoxin-treated rats.

S W Chang, … , P M Henson, N F Voelkel

S W Chang, … , P M Henson, N F Voelkel

Published May 1, 1987
Citation Information: J Clin Invest. 1987;79(5):1498-1509. https://doi.org/10.1172/JCI112980.

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Citations to this article (290)

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The accumulation of lipids and proteins during red blood cell storage: the roles of leucoreduction and experimental filtration Christopher C Silliman, Timothy Burke, Marguerite R Kelher	Blood Transfusion	2017
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Lipopolysaccharide Cross-Tolerance Delays Platelet-Activating Factor-Induced Sudden Death in Swiss Albino Mice: Involvement of Cyclooxygenase in Cross-Tolerance SP Jacob, CL Lakshmikanth, VH Chaithra, TR Kumari, CH Chen, TM McIntyre, GK Marathe, P Proost	PloS one	2016
Polymicrobial infections involving clinically relevant Gram-negative bacteria and fungi: Bacterial-fungal interactions S Dhamgaye, Y Qu, AY Peleg	Cellular Microbiology	2016
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Biosynthesis of Oxidized Lipid Mediators via Lipoprotein Associated Phospholipase A2 Hydrolysis of Extracellular Cardiolipin Induces Endothelial Toxicity JR Buland, KJ Wasserloos, VA Tyurin, YY Tyurina, AA Amoscato, RK Mallampalli, BB Chen, J Zhao, Y Zhao, S Ofori-Acquah, VE Kagan, BR Pitt	American journal of physiology. Lung cellular and molecular physiology	2016
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Platelet-activating Factor Contributes to Bacillus anthracis Lethal Toxin-associated Damage J Rivera, RS Sellers, W Zeng, N Rooijen, A Casadevall, DL Goldman	The Journal of biological chemistry	2014
Platelet Vascular Endothelial Growth Factor is a Potential Mediator of Transfusion-Related Acute Lung Injury JP Maloney	Journal of Pulmonary & Respiratory Medicine	2014
HMGB1 accelerates alveolar epithelial repair via an IL-1β- and αvβ6 integrin-dependent activation of TGF-β1 JF Pittet, H Koh, X Fang, K Iles, S Christiaans, N Anjun, BM Wagener, DW Park, JW Zmijewski, MA Matthay, J Roux	PloS one	2013
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Bacterial Clearance Is Improved in Septic Mice by Platelet-Activating Factor-Acetylhydrolase (PAF-AH) Administration MG Teixeira-da-Cunha, RN Gomes, N Roehrs, FA Bozza, SM Prescott, D Stafforini, GA Zimmerman, PT Bozza, HC Castro-Faria-Neto, JC Deng	PloS one	2013
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Induction of Shock After Intravenous Injection of Adenovirus Vectors: A Critical Role for Platelet-activating Factor Z Xu, JS Smith, J Tian, AP Byrnes	Molecular Therapy	2009
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Regulation of surfactant secretion in alveolar type II cells AV Andreeva, MA Kutuzov, TA Voyno-Yasenetskaya	American journal of physiology. Lung cellular and molecular physiology	2007
EXOGENOUS PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE REDUCES MORTALITY IN MICE WITH SYSTEMIC INFLAMMATORY RESPONSE SYNDROME AND SEPSIS RN Gomes, FA Bozza, RT Am??ncio, AM Japiass??, RC Vianna, AP Larangeira, JM Gouv??a, MS Bastos, GA Zimmerman, DM Stafforini, SM Prescott, PT Bozza, HC Castro-Faria-Neto	Shock	2006
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Regulating inflammation through the anti-inflammatory enzyme platelet-activating factor-acetylhydrolase HC Neto, DM Stafforini, SM Prescott, GA Zimmerman	Memórias do Instituto Oswaldo Cruz	2005
Regulation of inflammatory responses by activated protein C: the molecular mechanism(s) and therapeutic implications K Okajima	Clinical Chemistry and Laboratory Medicine	2004
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PAF-mediated pulmonary edema: a new role for acid sphingomyelinase and ceramide R Göggel, S Winoto-Morbach, G Vielhaber, Y Imai, K Lindner, L Brade, H Brade, S Ehlers, AS Slutsky, S Schütze, E Gulbins, S Uhlig	Nature Medicine	2004
Plasma and lipids from stored platelets cause acute lung injury in an animal model CC Silliman, AJ Bjornsen, TH Wyman, M Kelher, J Allard, S Bieber, NF Voelkel	Transfusion	2003
Recombinant platelet-activating factor acetylhydrolase to prevent acute respiratory distress syndrome and mortality in severe sepsis: Phase IIb, multicenter, randomized, placebo-controlled, clinical trial* DP Schuster, M Metzler, S Opal, S Lowry, R Balk, E Abraham, H Levy, G Slotman, E Coyne, S Souza, J Pribble	Critical Care Medicine	2003
Platelet-activating factor acetylhydrolase is increased in lung lavage fluid from patients with acute respiratory distress syndrome CK Grissom, JF Orme, LD Richer, TM McIntyre, GA Zimmerman, MR Elstad	Critical Care Medicine	2003
Platelet-Activating Factor: A Previously Unrecognized Mediator of Fever AI Ivanov, S Patel, VA Kulchitsky, AA Romanovsky	The Journal of Physiology	2003
Platelet-Activating Factor Synthesis by Neutrophils, Monocytes, and Endothelial Cells is Modulated by Nitric Oxide Production: F Mariano, B Bussolati, M Migliori, S Russo, G Triolo, G Camussi	Shock	2003
Antithrombin prevents endotoxin-induced hypotension by inhibiting the induction of nitric oxide synthase in rats H Isobe, K Okajima, M Uchiba, N Harada, H Okabe	Blood	2002
The Macrophage Response to Endotoxin Requires Platelet Activating Factor EM Bulger, S Arbabi, I Garcia, RV Maier	Shock	2002
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Platelet-Activating Factor–induced Pulmonary Edema Is Partly Mediated by Prostaglandin E 2 , E-Prostanoid 3-Receptors, and Potassium Channels R Göggel, S Hoffman, R Nüsing, S Narumiya, S Uhlig	American journal of respiratory and critical care medicine	2002
Role of platelet-activating factor in phosphatidylcholine secretion in primary cultures of rat type II pneumocytes E Benito, MA Bosch	Prostaglandins & Other Lipid Mediators	2002
Platelet-activating factor induces lung inflammation and leak in rats: Hydrogen peroxide production along neutrophil-lung endothelial cell interfaces YM Lee, BM Hybertson, HG Cho, JE Repine	Journal of Laboratory and Clinical Medicine	2002
Reactive oxygen species scavengers attenuate endotoxin-induced impairment of hypoxic pulmonary vasoconstriction in mice Hemanth A Baboolal, Fumito Ichinose, Roman Ullrich, Noriko Kawai, Kenneth D Bloch, Warren M Zapol	Anesthesiology	2002
Receptor-dependent Metabolism of Platelet-activating Factor in Murine Macrophages N Ohshima, S Ishii, T Izumi, T Shimizu	The Journal of biological chemistry	2002
Determination of the platelet activating factor in silicotic patients and its effect on fibroblasts Q Zhang, Y Mo, J Lou, X Zhu, Z Chen, L He, H Zhong	Environmental Health and Preventive Medicine	2001
Effects of a dual inhibitor of tumor necrosis factor-α and interleukin-1 on lipopolysaccharide-induced lung injury in rats: Involvement of the p38 mitogen-activated protein kinase pathway D Yoshinari, I Takeyoshi, Y Koibuchi, K Matsumoto, Y Kawashima, T Koyama, S Ohwada, Y Morishita	Critical Care Medicine	2001
Cardiac functional and structural alterations induced by endotoxin in rats: Importance of platelet-activating factor M Iwase, M Yokota, K Kitaichi, L Wang, K Takagi, T Nagasaka, H Izawa, T Hasegawa	Critical Care Medicine	2001
Cardiovascular Properties of Yangambin, a Lignan Isolated from Brazilian Plants E Tibiriçá	Cardiovascular Drug Reviews	2001
Atrial Natriuretic Peptide Blockade Exacerbates High Altitude Pulmonary Edema in Endotoxin-Primed Rats DC Irwin, J Rhodes, DC Baker, SE Nelson, A Tucker	High Altitude Medicine & Biology	2001
Determination of the Platelet Activating Factor in Silicotic Patients and its Effect on Fibroblasts Q ZHANG, Y MO, J LOU, X ZHU, Z CHEN, L HE, H ZHONG	Environmental Health and Preventive Medicine	2001
Effects of a dual inhibitor of tumor necrosis factor-α and interleukin-1 on lipopolysaccharide-induced lung injury in rats: Involvement of the p38 mitogen-activated protein kinase pathway: D Yoshinari, I Takeyoshi, Y Koibuchi, K Matsumoto, Y Kawashima, T Koyama, S Ohwada, Y Morishita	Critical Care Medicine	2001
Platelet-activating factor, eicosanoids, and bradykinin as targets for adjuvant therapies for sepsis MP Fink	Seminars in Pediatric Infectious Diseases	2001
Myocardial dysfunction in septic shock: Part II. Role of cytokines and nitric oxide A Kumar, A Krieger, S Symeoneides, A Kumar, JE Parrillo	Journal of Cardiothoracic and Vascular Anesthesia	2001
PAF increases vascular permeability without increasing pulmonary arterial pressure in the rat LC Clavijo, MB Carter, PJ Matheson, MA Wilson, WB Wead, RN Garrison	Journal of applied physiology	2001
Reactive Oxygen Species and Endotoxic Shock: Effect of Dimethylthiourea U Pattanaik, K Prasad	Journal of cardiovascular pharmacology and therapeutics	2001
PAF receptor antagonist modulates neutrophil responses with thermal injury in vivo N Fazal, WM Al-Ghoul, MA Choudhry, MM Sayeed	American journal of physiology. Cell physiology	2001
Attenuation of Hypoxic Pulmonary Vasoconstriction by Endotoxemia Requires 5-Lipoxygenase in Mice F Ichinose, WM Zapol, A Sapirstein, R Ullrich, AM Tager, K Coggins, R Jones, KD Bloch	Circulation research	2001
FR128998 (a PAF receptor antagonist) counters the increased pulmonary vascular resistance associated with ischemia-reperfusion injury in the canine lung S Iwazaki, I Takeyoshi, S Ohwada, Y Sunose, M Aiba, H Tsutsumi, Y Kawashima, K Matsumoto, Y Morishita	International Journal of Angiology	2001
Microcirculatory dysfunction in sepsis: a pathogenetic basis for therapy? HA Lehr, F Bittinger, CJ Kirkpatrick	The Journal of Pathology	2000
Platelet-activating factor (PAF) receptor and genetically engineered PAF receptor mutant mice S Ishii, T Shimizu	Progress in Lipid Research	2000
Platelet-Activating Factor and Bacteremia-Induced Pulmonary Hypertension LC Clavijo, MB Carter, PJ Matheson, LA Wills-Frank, MA Wilson, WB Wead, RN Garrison	Journal of Surgical Research	2000
Phase II multicenter clinical study of the platelet-activating factor receptor antagonist BB-882 in the treatment of sepsis: JL Vincent, H Spapen, J Bakker, NR Webster, L Curtis	Critical Care Medicine	2000
Differential inducible nitric oxide synthase expression in systemic and pulmonary vessels after endotoxin EJ Pulido, BD Shames, DA Fullerton, BC Sheridan, CH Selzman, F Gamboni-Robertson, DD Bensard, RC McIntyre	American Journal of Physiology - Regulatory, Integrative and Comparative Physiology	2000
Role of Platelet-Activating Factor in Cardiovascular Pathophysiology G Montrucchio, G Alloatti, G Camussi	Physiological reviews	2000
Platelet-activating factor mediates acid-induced lung injury in genetically engineered mice T Nagase, S Ishii, K Kume, N Uozumi, T Izumi, Y Ouchi, T Shimizu	Journal of Clinical Investigation	1999
Dietary α-linolenate suppresses endotoxin-induced platelet-activating factor production in rat kidney K Oh-hashi, T Takahashi, A Tanabe, S Watanabe, H Okuyama	Lipids	1999
L-arginine attenuates endothelial dysfunction in endotoxin-induced lung injury BC Sheridan, RC Mclntyre, DR Meldrum, DA Fullerton	Surgery	1999
Potential role of platelet activating factor in acute renal failure JM Lopez-Novoa	Kidney International	1999
Cardiotrophin-1 Attenuates Endotoxin-Induced Acute Lung Injury EJ Pulido, BD Shames, D Pennica, RM O'Leary, DD Bensard, BS Cain, RC McIntyre	Journal of Surgical Research	1999
Quinolines Attenuate PAF-induced Pulmonary Pressor Responses and Edema Formation S Falk, R Göggel, U Heydasch, F Brasch, KM Müller, A Wendel, S Uhlig	American journal of respiratory and critical care medicine	1999
Neutrophil Apoptosis in the Lung after Hemorrhage or Endotoxemia: Apoptosis and Migration Are Independent of IL-1β MV Parsey, D Kaneko, R Shenkar, E Abraham	Clinical Immunology	1999
Inhibition of PARS attenuates endotoxin-induced dysfunction of pulmonary vasorelaxation EJ Pulido, BD Shames, CH Selzman, HA Barton, A Banerjee, DD Bensard, RC McIntyre	American journal of physiology. Lung cellular and molecular physiology	1999
Suppression of lipopolysaccharide-induced nitric oxide synthase expression by platelet-activating factor receptor antagonists in the rat liver and cultured rat kupffer cells SB Mustafa, BD Flickinger, MS Olson	Hepatology	1999
Interaction of platelet-activating factor, spleen and atrial natriuretic peptide in plasma volume regulation during endotoxaemia in rats XW Qu, RA Rozenfeld, W Huang, SE Crawford, F Gonzalez-Crussi, W Hsueh	The Journal of Physiology	1998
BN 52021 (a platelet activating factor-receptor antagonist) decreases alveolar macrophage-mediated lung injury in experimental extrinsic allergic alveolitis JL Pérez-Arellano, T Martín, JM López-Novoa, ML Sánchez, A Montero, A Jiménez	Mediators of Inflammation	1998
Possible Role of Platelet-Activating Factor in thein VivoExpression of Tissue Factor in Neutrophils H Todoroki, A Higure, K Okamoto, K Okazaki, Y Nagafuchi, S Takeda, H Katoh, H Itoh, K Ohsato, S Nakamura	Journal of Surgical Research	1998
Acute pulmonary lesions in sheep experimentally infected with bovine viral diarrhoea virus J Meehan, H Lehmkuhl, R Cutlip, S Bolin	Journal of Comparative Pathology	1998
Platelet-activating Factor Plays a Pivotal Role in the Induction of Experimental Lung Injury JM Miotla, PK Jeffery, PG Hellewell	American journal of respiratory cell and molecular biology	1998
Septic Shock B Klosterhalfen, RS Bhardwaj	General Pharmacology: The Vascular System	1998
Effects of Endotoxin on Lung Pericytesin Vitro J Khoury, D Langleben	Microvascular Research	1998
Effect of platelet-activating factor-receptor antagonism on endotoxin-induced lung dysfunction in sheep JR Snapper, W Lu, PL Lefferts, JS Thabes	Journal of applied physiology	1998
l -Arginine prevents lung neutrophil accumulation and preserves pulmonary endothelial function after endotoxin BC Sheridan, RC McIntyre, DR Meldrum, DA Fullerton	American journal of physiology. Lung cellular and molecular physiology	1998
Oxygen Free Radicals and Endotoxic Shock: Effect of Flaxseed U Pattanaik, K Prasad	Journal of cardiovascular pharmacology and therapeutics	1998
Platelet-activating factor modulates pulmonary vasomotor tone in the perinatal lamb BO Ibe, S Hibler, JU Raj	Journal of applied physiology	1998
Endotoxin Differentially Impairs Receptor-Mediated Relaxation in Rat Isolated Pulmonary and Thoracic Aortic Vessels: RC McIntyre, EJ Pulido, B Sheridan, DR Meldrum, DD Bensard, DA Fullerton	The Journal of Trauma: Injury, Infection and Critical Care	1998
Pentoxifylline attenuates LPS-induced bronchial hyperresponsiveness but not the increase in exhaled nitric oxide G Rolla, C Bucca, L Brussino, L Dutto, P Colagrande, S Polizzi	Clinical & Experimental Allergy	1997
Relevance of platelet-activating factor in inflammation and sepsis: Mechanisms and kinetics of removal in extracorporeal treatments C Tetta, F Mariano, J Buades, C Ronco, ML Wratten, G Camussi	American Journal of Kidney Diseases	1997
Comparison of the reversed passive Arthus and local Shwartzman reactions of rabbit skin: effects of the long-acting PAF antagonist UK-74,505 KE Norman, TJ Williams, AG Rossi	British Journal of Pharmacology	1997
Lexipafant (BB-882): A Potent New Platelet-Activating Factor Receptor Antagonist FM Abu-Zidan, S Walther, S Lennquist	Cardiovascular Drug Reviews	1997
Bronchial hyperreactivity, increased endotoxin lethality and melanocytic tumorigenesis in transgenic mice overexpressing platelet-activating factor receptor S Ishii, T Nagase, F Tashiro, K Ikuta, S Sato, I Waga, K Kume, J Miyazaki, T Shimizu	The EMBO Journal	1997
Phosphodiesterase Inhibition Overcomes Pulmonary Vasomotor Dysfunction in Acute Lung Injury BC Sheridan, RC McIntyre, DR Meldrum, DA Fullerton	Journal of Surgical Research	1997
Pancreatic Damage Resulting from Temporary Portal Triad Interruption during Partial Hepatectomy: Protective Effect of a Prostaglandin I2Analogue H Ochiai, S Nakamura, S Suzuki, S Baba, SB M.D.	Journal of Surgical Research	1997
The Role of Platelet-Activating Factor in Conscious, Normotensive Endotoxemia K Ephgrave, T Kremer, K Broadhurst, J Cullen	Journal of Surgical Research	1997
Pentoxifylline Treatment Attenuates Pulmonary Vasomotor Dysfunction in Acute Lung Injury BC Sheridan, RC McIntyre, DR Meldrum, DA Fullerton	Journal of Surgical Research	1997
Platelet-Activating Factor (PAF) Up-Regulates Plasma and Tissue PAF-Acetylhydrolase Activity in the Rat: Effect of Cycloheximide H Wang, XD Tan, XW Qu, H Chang, DG Remick, F Gonzalez-Crussi, W Hsueh	Pediatric Research	1997
Advances in Molecular and Cell Biology KJ Clemetson	Advances in Molecular and Cell Biology	1997
Effect of SR 27417, a novel PAF antagonist on antigen-induced hypotension in the rat JM Herberta, A Bernat, E Tibiriç	Journal of Lipid Mediators and Cell Signalling	1997
Nitric Oxide Synthase Inhibition Restores Hypoxic Pulmonary Vasoconstriction in Sepsis SR Fischer, DJ Deyo, HG Bone, RO McGUIRE, LD Traber, DL Traber	American journal of respiratory and critical care medicine	1997
Pharmacological evidence for the putative existence of two different subtypes of PAF receptors on platelets and leukocytes; studies with yangambin JM Herbert, HC Castro-Faria-Neto, JM Barbosa-Filho, RS Cordeiro, E Tibiriça	Journal of Lipid Mediators and Cell Signalling	1997
Gender Differences in Nitric Oxide Production by Alveolar Macrophages in Ethanol plus Lipopolysaccharide-Treated Rats JA Spitzer	Nitric Oxide	1997
Role of superoxide and nitric oxide in platelet-activating factor-induced acute lung injury, hypotension, and mortality in rats: T Yoshikawa, H Takano, H Yamamoto, Y Nakahashi, T Yamaguchi, T Arimoto, M Kondo	Critical Care Medicine	1997
Endotoxin differentially impairs cyclic guanosine monophosphate-mediated relaxation in the pulmonary and systemic circulations: RC McIntyre, B Sheridan, J Agrafojo, DA Fullerton	Critical Care Medicine	1997
New Therapies in Sepsis JL Vincent	Chest	1997
Pharmacology of ABT-491, a highly potent platelet-activating factor receptor antagonist DH Albert, TJ Magoc, P Tapang, G Luo, DW Morgan, M Curtin, GS Sheppard, L Xu, HR Heyman, SK Davidsen, JB Summers, GW Carter	European Journal of Pharmacology	1997
A Novel Model to Study the Effects of Burn Lymph on Pulmonary Vascular Hemodynamic Variables: Q Hao, AL Hyman, EU Choe, LM Flint, JJ Ferrara	The Journal of Trauma: Injury, Infection and Critical Care	1997
Neutrophils Mediate Pulmonary Vasomotor Dysfunction in Endotoxin-induced Acute Lung Injury: BC Sheridan, RC McIntyre, EE Moore, DR Meldrum, J Agrafojo, DA Fullerton	The Journal of Trauma: Injury, Infection and Critical Care	1997
Platelets and Their Factors F von Bruchhausen, U Walter		1997
Liver cirrhosis induces renal and liver phospholipase A2 activity in rats BS Vishwanath, FJ Frey, G Escher, J Reichen, BM Frey	Journal of Clinical Investigation	1996
Neutrophil-induced lung damage after hepatic ischemia and endotoxemia GM McGuire, P Liu, H Jaeschke	Free radical biology & medicine	1996
Impairment of endothelial-dependent pulmonary vasorelaxation after mesenteric ischemia/reperfusion DA Fullerton, JH Eisenach, RS Friese, J Agrafojo, BC Sheridan, RC McIntyre	Surgery	1996
Platelet activating factor receptor blockade alone or in combination with leukotriene synthesis inhibition does not ameliorate α-naphthylisothiocyanate-induced hepatotoxicity MB Bailie, JM Pearson, GD Fink, RA Roth	Toxicology Letters	1996
Activation of Circulating Polymorphonuclear Leukocytes in Preterm Infants with Severe Idiopathic Respiratory Distress Syndrome F Brus, WV Oeveren, A Okken, SB Oetomo	Pediatric Research	1996
Effects of UR-12633, a new antagonist of platelet-activating factor, in rodent models of endotoxic shock M Giral, D Balsa, R Ferrando, M Merlos, J Garcia-Rafanell, J Forn	British Journal of Pharmacology	1996
PULMONARY INTRAVASCULAR PHAGOCYTOSIS IN LIVER DISEASE SW Chang, N Ohara	Clinics in Chest Medicine	1996
Protective effects of Yangambin — a naturally occurring platelet-activating factor (PAF) receptor antagonist — on anaphylactic shock in rats R Ribeiro, FA Carvalho, JM Barbosa-Filho, RS Cordeiro, EV Tibiriçá	Phytomedicine	1996
Activation of Circulating Polymorphonuclear Leukocytes in Preterm Infants with Severe Idiopathic Respiratory Distress Syndrome: F Brus, WV Oeveren, A Okken, SB Oetomo	Pediatric Research	1996
Endotoxin induces PAF production in the rat ileum: Quantitation of tissue PAF by an improved method X Qu, L Huang, T Burthart, SE Crawford, MS Caplan, W Hsueh	Prostaglandins	1996
Influence of heat shock protein 70 and metallothionein induction by Zinc-Bis-(DL-Hydrogenaspartate) on the release of inflammatory mediators in a porcine model of recurrent endotoxemia B Klosterhalfen, C Töns, S Hauptmann, L Tietze, FA Offner, W Küpper, CJ Kirkpatrick	Biochemical Pharmacology	1996
Platelet-Activating Factor and Related Lipid Mediators 2 S Nigam, G Kunkel, SM Prescott		1996
Role of Platelet-Activating Factor and Prostanoids in Hemodynamic Changes in Rat Experimental Endotoxic Shock T Ebara, K Miura, T Matsuura, M Imanishi, Y Yamano, S Kim, H Iwao	The Japanese Journal of Pharmacology	1996
ARDS Acute Respiratory Distress in Adults TW Evans, C Haslett		1996
The pathogenesis of ventilator-associated pneumonia: II. The lower respiratory tract GU Meduri, RJ Estes	Intensive Care Medicine	1995
Role of hydroxyl radical in the stimulation of arachidonic acid release caused by H2O2 in pulmonary smooth muscle cells: Protective effect of anion channel blocker S Chakraborti, SK Batabyal, T Chakraborti	Molecular and Cellular Biochemistry	1995
Endotoxin-resistant mice are protected from PAF-induced bowel injury and death role of TNF, complement activation, and endogenous PAF production X Sun, MS Caplan, Y Liu, W Hsueh	Digestive Diseases and Sciences	1995
Does Early Posttreatment with Lidocaine Attenuate Endotoxin-induced Acute Lung Injury in Rabbits? K Nishina, K Mikawa, N Maekawa, Y Takao, H Obara	Anesthesiology	1995
Nitric Oxide Synthase Inhibition and Acute Renal Ischemia: Effect on Systemic Hemodynamics and Mortality I Atanasova, TJ Burke, IF McMurtry, RW Schrier	Renal Failure	1995
Role for intracellular platelet-activating factor in the circulatory failure in a model of gram-positive shock SJ de Kimpe, C Thiemermann, JR Vane	British Journal of Pharmacology	1995
Comparative study of endotoxin-induced hypotension in kininogen-deficient rats with that in normal rats A Ueno, H Ishida, S Oh-ishi	British Journal of Pharmacology	1995
The role of platelet-activating factor in lipopolysaccharide-induced myocardial depression in guinea pigs SO Heard, I Toth, M Perkins	Journal of Critical Care	1995
Does Early Posttreatment with Lidocaine Attenuate Endotoxin-induced Acute Lung Injury in Rabbits?: K Nishina, K Mikawa, N Maekawa, Y Takao, H Obara	Anesthesiology	1995
Pharmacokinetics and catabolism of tumor necrosis factor-α in rat lungs GP Pessina, L Paulesu, F Corradeschi, E Luzzi, C Aldinucci, M Tanzini, V Bocci	Immunopharmacology	1995
Signal sorting by G-protein-linked receptors G Milligan	Advances in pharmacology (San Diego, Calif.)	1995
Sepsis in the critically ill patient CC Baker, T Huynh	Current Problems in Surgery	1995
Current understanding of sepsis: criticism and a proposal R Rabinovici, LF Neville, G Feuerstein	Journal of Endotoxin Research	1995
Pulmonary TNFα is a critical mediator in Adult Respiratory Distress Syndrome GZ Feuerstein, LF Neville, R Rabinovici	Journal of Endotoxin Research	1995
Hemodynamic Changes and Gut Barrier Function in Sequential Hemorrhagic and Endotoxic Shock: RG Turnbull, JA Talbot, SM Hamilton	The Journal of Trauma: Injury, Infection and Critical Care	1995
The Splanchnic Circulation MR Pinsky, JF Dhainaut, A Artigas		1995
The platelet activating factor as a pivotal mediator of shock after liver ischemia T Fukuoka, Y Nakajima, H Nakano	Surgery Today	1995
Binding between lipopolysaccharide and cecropin A AJ Lucca, TJ Jacks, KA Brogden	Molecular and Cellular Biochemistry	1995
Effect of tumor necrosis factor receptor binding protein on cell infiltration induced by lipopolysaccharide and sephadex beads in guinea pig lung DM Conroy, JN Francischi, P Sirois	Inflammation	1995
Clinical Trials for the Treatment of Sepsis JL Vincent, WJ Sibbald		1995
Chronic biliary obstruction induces pulmonary intravascular phagocytosis and endotoxin sensitivity in rats SW Chang, N Ohara	Journal of Clinical Investigation	1994
Amelioration of experimental acute pancreatitis with a potent platelet-activating factor antagonist LJ Formela, LM Wood, M Whittaker, AN Kingsnorth	British Journal of Surgery	1994
Type 1 prophospholipase A2 propeptide in acute lung injury D Rae, N Beechey-Newman, N Sumar, J Hermon-Taylor, J Porter, D Bennett	The Lancet	1994
P-selectin and platelet-activating factor mediate initial endotoxin-induced neutropenia AF Coughlan, H Hau, LC Dunlop, MC Berndt, WW Hancock	Journal of Experimental Medicine	1994
Morphometric evidence of changes in the vasculature of the uterine tube of mice induced by the 2-cell embryo on the second day of pregnancy BA Stein, C O'Neill	Journal of Anatomy	1994
Long-lasting inhibitory activity of the hetrazepinic BN 50730 on exudation and cellular alterations evoked by PAF and LPS AL Pires, PM Silva, C Pasquale, HC Castro-Faria-Neto, PT Bozza, RS Cordeiro, GA Rae, P Braquet, V Lagente, MA Martins	British Journal of Pharmacology	1994
Potential etiologic role of PAF in two major septic complications; Disseminated intravascular coagulation and multiple organ failure M Ou, J Kambayashi, T Kawasaki, Y Uemura, K Shinozaki, E Shiba, M Sakon, M Yukawa, T Mori	Thrombosis Research	1994
Increased prostaglandin I2 and thromboxane A2 production by rat dental pulp after intravenous administration of endotoxin M Hirafuji, H Shinoda	Archives of Oral Biology	1994
Lipid Mediators JR Vane, RM Botting	Lipid Mediators	1994
Role of platelet-activating factor (PAF) and prostaglandins in colonic motor and secretory disturbances induced by Escerichia coli endotoxin in conscious rats L Pons, L Buéno, MT Droy-Lefaix	Prostaglandins	1994
Effect of FR128998, a novel PAF receptor antagonist, on endotoxin-induced disseminated intravascular coagulation Y Yokota, N Inamura, M Asano, Y Yamamoto, K Nakahara, Y Notsu, T Ono, M Watanabe	European Journal of Pharmacology	1994
The production of experimental cholecystitis by endotoxin DL Kaminski, WK Feinstein, DY G.	Prostaglandins	1994
Characterization of Immunological Activity of a Low Toxicity Antitumor Lipopolysaccharide from Bordetella pertussis M Ohnishi, S Kimura, M Yamazaki, S Abe, H Yamaguchi	Microbiology and Immunology	1994
Lipopolysaccharide-induced pleural neutrophil accumulation depends on marrow neutrophils and platelet-activating factor PT Bozza, HC Castro-Faria-Neto, AR Silva, AP Larangeira, PM Silva, MA Martins, RS Cordeiro	European Journal of Pharmacology: Environmental Toxicology and Pharmacology	1994
Inflammatory Mediators and Intestinal Injury MS Caplan, W MacKendrick	Clinics in Perinatology	1994
Free Radicals in Diagnostic Medicine D Armstrong		1994
Effects of non-steroidal anti-inflammatory drugs on polymorphonuclear leukocyte functions in vitro: focus on fenamates H Kankaanranta, E Moilanen, H Vapaatalo	Naunyn-Schmiedeberg's Archives of Pharmacology	1994
Tissue eicosanoids and vascular permeability in rats with chronic biliary obstruction N Ohara, NF Voelke, SW Chang	Hepatology	1993
Effects of the PAF antagonists bepafant and L-659, 989 in endotoxic and septic shock HM Tang, DY Teshima, BK Lum	Drug Development Research	1993
Outer-membrane porins from Gram-negative bacteria stimulate platelet-activating-factor biosynthesis by cultured human endothelial cells MA TUFANO, L BIANCONE, F ROSSANO, C CAPASSO, A BARONI, A MARTINO, EL IORIO, L SILVESTRO, G CAMUSSI	European Journal of Biochemistry	1993
Administration of a receptor antagonist for platelet-activating factor during equine endotoxaemia JB Carrick, DD Morris, JN Moore	Equine Veterinary Journal	1993
Anti-inflammatory activities of Emblica officinalis Gaertn leaf extracts MZ Asmawi, H Kankaanranta, E Moilanen, H Vapaatalo	Journal of Pharmacy and Pharmacology	1993
Modulation by nitric oxide of platelet-activating factor-induced albumin extravasation in the conscious rat JG Filep, E Földes-Filep	British Journal of Pharmacology	1993
An antagonist of platelet-activating factor suppresses endotoxin-induced tumor necrosis factor and mortality in mice pretreated with carrageenan M Ogata, T Matsumoto, K Koga, I Takenaka, M Kamochi, T Sata, S Yoshida, A Shigematsu	Infection and immunity	1993
Interference of a neutrophil recruitment inhibitory factor upon the accumulation of inflammatory cells and airway hyperreactivity in sensitized guinea-pigs after intranasal antigen challenge BM Tavares-Murta, J Lefort, FQ Cunha, SH Ferreira, BB Vargaftig	British Journal of Pharmacology	1993
Pharmacological modulation of lipopolysaccharide-induced pleural eosinophilia in the rat; a role for a newly generated protein PT Bozza, HC Castro-Faria-Neto, MA Martins, AP Larangeira, JE Perales, PM Silva, RS Cordeiro	European Journal of Pharmacology: Environmental Toxicology and Pharmacology	1993
Immunopharmacology of the Gastrointestinal System L Parente, KG Mugridge	Immunopharmacology of the Gastrointestinal System	1993
Endotoxin in Human Disease CA Manthous, JB Hall, RW Samsel	Chest	1993
Secondary Organ Dysfunction: From Clinical Perspectives to Molecular Mediators MD Cipolle, MD Pasquale, FB Cerra	Critical Care Clinics	1993
Platelet-activating factor contributes to the induction of nitric oxide synthase by bacterial lipopolysaccharide C Szabó, CC Wu, JA Mitchell, SS Gross, C Thiemermann, JR Vane	Circulation research	1993
Shock, Sepsis, and Organ Failure G Schlag, H Redl, D Traber		1993
Host Defense Dysfunction in Trauma, Shock and Sepsis E Faist, JL Meakins, FW Schildberg		1993
Pathophysiology of Shock, Sepsis, and Organ Failure G Schlag, H Redl		1993
Interactions between synthesis of platelet-activating factor and leukotriene B4 in isolated human polymorphonuclear leukocytes E Moilanen, , H Kankaanranta, MM Nieminen, H Vapaatalo	Inflammation	1993
Alterations of bacterial clearance induced by endotoxin and tumor necrosis factor T Koch, HP Duncker, R Axt, HG Schiefer, K van Ackern, H Neuhof	Infection and immunity	1993
Role of tumour necrosis factor and reactive oxygen intermediates in lipopolysaccharide-induced pulmonary oedema and lethality. Gatti S, Faggioni R, Echtenacher B, Ghezzi P	Clinical & Experimental Immunology	1993
Platelet-Activating Factor and Structurally Related Alkyl Ehter Lipids OP Santos, M Boim, E Barros, E Pirotzky, P Braquet, N Schor	Platelet-Activating Factor and Structurally Related Alkyl Ehter Lipids	1992
Endotoxin, septic shock and acute lung injury: Neutrophils, macrophages and inflammatory mediators CR Welbourn, Y Young	British Journal of Surgery	1992
Porins and lipopolysaccharide stimulate platelet activating factor synthesis by human mesangial cells G Camussi, L Biancone, EL Iorio, L Silvestro, RD Col, C Capasso, F Rossano, L Servillo, C Balestrieri, MA Tufano	Kidney International	1992
Respiratory Distress Resulting from Acute Lung Injury in the Veterinary Patient CW Frevert, AE Warner	Journal of Veterinary Internal Medicine	1992
SRI 63-675: A Platelet Activating Factor Receptor Antagonist NC Olson	Cardiovascular Drug Reviews	1992
Cytokine gene regulation by PGE(2), LTB(4) and PAF M Rola-Pleszczynski, J Stankova	Mediators of Inflammation	1992
Detoxified exoantigens and phosphatidylinositol derivatives inhibit tumor necrosis factor induction by malarial exoantigens CA Bate, J Taverne, JH Playfair	Infection and immunity	1992
The role of platelet-activating factor and peptidoleukotrienes in the vascular changes of rat passive anaphylaxis S Fernández-Gallardo, MA Gijón, C García, V Furio, FT Liu, MS Crespo	British Journal of Pharmacology	1992
Role of platelet-activating factor in pancreatitis-associated acute lung injury in the rat W Zhou, MO McCollum, BA Levine, MS Olson	The American Journal of Pathology	1992
Platelet-activating factor augments tumor necrosis factor and procoagulant activity RV Maier, GB Hahnel, JR Fletcher	Journal of Surgical Research	1992
Effects of thromboxane synthase and cyclooxygenase inhibition on PAF-induced changes in lung function and arachidonic acid metabolism DS Trochtenberg, PL Lefferts, GA King, YS Hwang, BW Christman, JR Snapper	Prostaglandins	1992
Acute changes in vasoactive lipid mediators in experimental hyaline membrane disease WE Truog, JC Jackson, TA Standaert, SE Juul, JH Murphy, WA Hodson, WR Henderson	Respiration Physiology	1992
Pulmonary Circulatory Dysfunction in Rats with Biliary Cirrhosis: An Animal Model of the Hepatopulmonary Syndrome SW Chang, N Ohara	American journal of respiratory and critical care medicine	1992
Tumor Necrosis Factor Causes Bronchial Hyperresponsiveness in Rats JC Kips, J Tavernier, RA Pauwels	American journal of respiratory and critical care medicine	1992
High Bronchoalveolar Levels of Tumor Necrosis Factor and Its Inhibitors, Interleukin-1, Interferon, and Elastase, in Patients with Adult Respiratory Distress Syndrome after Trauma, Shock, or Sepsis PM Suter, S Suter, E Girardin, P Roux-Lombard, GE Grau, JM Dayer	American journal of respiratory and critical care medicine	1992
Multiple organ failure syndrome FB Cerra	Disease-a-Month	1992
Time course of various inflammatory mediators during recurrent endotoxemia B Klosterhalfen, K Hörstmann-Jungemann, P Vogel, S Flohé, F Offner, CJ Kirkpatrick, PC Heinrich	Biochemical Pharmacology	1992
7S Collagen in Bronchoalveolar Lavage Fluid of Patients with Adult Respiratory Distress Syndrome Y Kondoh, H Taniguchi, F Taki, K Takagi, T Satake	Chest	1992
New Aspects on Respiratory Failure E Rügheimer		1992
Mediators of Sepsis M Lamy, LG Thijs		1992
Microbial Infections H Friedman, TW Klein, H Yamaguchi		1992
The pulmonary physician and critical care. 4. A new look at the pulmonary circulation in acute lung injury GA Fox, DG McCormack	Thorax	1992
Platelet-activating factor in cardiovascular stress situations R Rabinovici, TL Yue, G Feuerstein	Lipids	1991
Platelet-activating factor type activity in plasma from patients with septicemia and other diseases HO Heuer, H Darius, HF Lohmann, J Meyer, M Schierenberg, N Treese	Lipids	1991
Platelet Activating Factor and Asthma PJ Barnes	Annals of the New York Academy of Sciences	1991
The molecular action of tumor necrosis factor-alpha G CAMUSSI, E ALBANO, C TETTA, F BUSSOLINO	European Journal of Biochemistry	1991
The cell in shock: the origin of multiple organ failure G Schlag, H Redl, S Hallström	Resuscitation	1991
Platelet-activating factor in porcine Pseudomonas acute lung injury K Byrne, CN Sessler, PD Carey, TD Sielaff, A Vasquez, JL Tatum, JI Hirsch, HJ Sugerman	Journal of Surgical Research	1991
Primed neutrophils injure rat lung through a platelet-activating factor-dependent mechanism BO Anderson, RS Poggetti, PF Shanley, DD Bensard, JM Pitman, DW Nelson, GJ Whitman, A Banerjee, AH Harken	Journal of Surgical Research	1991
Protein Kinase C Regulates the Synthesis of Platelet-activating Factor by Human Monocytes MR Elstad, TM McIntyre, SM Prescott, GA Zimmerman	American journal of respiratory cell and molecular biology	1991
The role of platelet activating factor (PAF) in the pathogenesis of gastric ulcers J Sugatani, K Fujimura, T Mizuno, Y Sameshima, K Saito	Prostaglandins, Leukotrienes and Essential Fatty Acids	1991
Protective effect of SR 27417, a novel PAF antagonist, on lethal anaphylactic and endotoxin-induced shock in mice JM Herbert, L Lespy, JP Maffrand	European Journal of Pharmacology	1991
Human Macrophages Secrete Platelet-Activating Factor Acetylhydrolase MR Elstad, DM Stafforini, SM Prescott, TM McIntyre, GA Zimmerman	Chest	1991
Immunosuppression in Trauma Patients DB Hoyt, AN Ozkan	Journal of Intensive Care Medicine	1991
Multiple Organ Failure Syndrome—Part I: Epidemiology, Prognosis, and Pathophysiology SO Heard, MP Fink	Journal of Intensive Care Medicine	1991
Priming by platelet-activating factor of endotoxin-induced lung injury and cardiovascular shock R Rabinovici, KM Esser, PG Lysko, TL Yue, DE Griswold, LM Hillegass, PJ Bugelski, JM Hallenbeck, G Feuerstein	Circulation research	1991
Cell-Cell Interactions in the Release of Inflammatory Mediators PY Wong, CN Serhan		1991
Sleep and Health Risk JH Peter, T Penzel, T Podszus, P von Wichert		1991
EJB Reviews 1991 P Christen, E Hofmann		1991
Lung injury in acute experimental pancreatitis, in rats: II. Functional Studies CO Feddersen, S Willemer, W Karges, A Püchner, G Adler, PV Wichert	International Journal of Gastrointestinal Cancer	1991
Respiratory syncytial virus infection of human mononuclear phagocytes stimulates synthesis of platelet-activating factor A Villani, NM Cirino, E Baldi, M Kester, ER McFadden, JR Panuska	The Journal of biological chemistry	1991
Primed stimulation of isolated perfused rabbit lung by endotoxin and platelet activating factor induces enhanced production of thromboxane and lung injury WL Salzer, CE McCall	Journal of Clinical Investigation	1990
Preclinical and clinical pharmacology of platelet-activating factor receptor antagonists DA Handley	Medicinal Research Reviews	1990
Platelet activating factor receptor antagonist improves survival and attenuates eicosanoid release in severe endotoxemia JR Fletcher, AG DiSimone, MA Earnest	Annals of Surgery	1990
Bleomycin-induced lung injury in the rat: effects of the platelet-activating factor (PAF) receptor antagonist BN 52021 and platelet depletion TW Evans, RJ McAnulty, DF Rogers, KF Chung, PJ Barnes, GJ Laurent	Environmental Health Perspectives	1990
Effects of in vivo 'priming' on endotoxin-induced hypotension and tissue injury. The role of PAF and tumor necrosis factor XM Sun, W Hsueh, G Torre-Amione	The American Journal of Pathology	1990
Evidence for platelet-activating factor as a late-phase mediator of chronic pancreatitis in the rat WG Zhou, W Chao, BA Levine, MS Olson	The American Journal of Pathology	1990
Endotoxin-induced myocardial depression in rats: Effect of ibuprofen and SDZ 64-688, a platelet activating factor receptor antagonist TD Baum, SO Heard, HS Feldman, CA Latka, MP Fink	Journal of Surgical Research	1990
The potential role of platelet-activating factor in shock and ischemia D Hosford, P Braquet	Journal of Critical Care	1990
Myocardial function in septic shock MM Parker, JE Parrillo	Journal of Critical Care	1990
Necrotizing enterocolitis: Role of platelet activating factor, endotoxin, and tumor necrosis factor MS Caplan, W Hsueh	The Journal of Pediatrics	1990
Pharmacologic profile of BN 50739, a new PAF antagonist and TL Yue, R Rabinovici, M Farhat, G Feuerstein	Prostaglandins	1990
Endotoxin releases platelet-activating factor from human monocytes in vitro HA Leaver, JM Qu, G Smith, A Howie, WB Ross, PL Yap	Immunopharmacology	1990
Role of platelet activating factor and tumor necrosis factor-alpha in neonatal necrotizing enterocolitis MS Caplan, XM Sun, W Hsueh, JR Hageman	The Journal of Pediatrics	1990
Effect of Platelet-activating Factor Receptor Antagonism on Endotoxin-induced Lung Dysfunction in Awake Sheep BW Christman, PL Lefferts, IA Blair, JR Snapper	American journal of respiratory and critical care medicine	1990
Circulating Plasma Platelet Activating Factor in Persistent Pulmonary Hypertension of the Newborn MS Caplan, W Hsueh, XM Sun, SS Gidding, JR Hageman	American journal of respiratory and critical care medicine	1990
The role of platelet-activating factor in inflammation G Camussi, C Tetta, C Baglioni	Clinical Immunology and Immunopathology	1990
Effect of a platelet activating factor antagonist (CV6209) on shock caused by temporary hepatic inflow occlusion T Fukuoka, Y Nakajima, M Matsumoto, M Segawa, H Kanehiro, M Hisanaga, T Wada, H Nakano	Life Sciences	1990
Hypoxia causes ischemic bowel necrosis in rats: The role of platelet-activating factor (PAF-acether) MS Caplan, XM Sun, W Hsueh	Gastroenterology	1990
Mechanisms of pulmonary edema induced by tumor necrosis factor-alpha DC Hocking, PG Phillips, TJ Ferro, A Johnson	Circulation research	1990
Phospholipase A2-induced lung edema and its mechanism in isolated perfused guinea pig lung SF Chen, SH Li, X Fei, ZL Wu	Inflammation	1990
Evidence for the role of platelet-activating factor in immune complex vasculitis in the rat JS Warren, DM Mandel, KJ Johnson, PA Ward	Journal of Clinical Investigation	1989
Occupancy of platelet receptors for platelet-activating factor in patients with septicemia FL Diez, ML Nieto, S Fernandez-Gallardo, MA Gijon, MS Crespo	Journal of Clinical Investigation	1989
Inhibition of endotoxin-induced bacterial translocation in mice EA Deitch, L Ma, WJ Ma, MB Grisham, DN Granger, RD Specian, RD Berg	Journal of Clinical Investigation	1989
The adult respiratory distress syndrome NF Voelkel	Klinische Wochenschrift	1989
Protection against pulmonary oxygen toxicity by interleukin-1 and tumor necrosis factor: Role of antioxidant enzymes and effect of cyclooxygenase inhibitors CW White, P Ghezzi	Biotherapy	1989
Hypoxia increases plasma glutathione disulfide in rats SW Chang, TJ Stelzner, JV Weil, NF Voelkel	Lung	1989
Endotoxin-induced ascites formation in the rat: Partial mediation by platelet-activating factor F Guarner, JL Wallace, WK Macnaughton, GC Ibbotson, V Arroyo, J Rodés	Hepatology	1989
Platelet activating factor is produced during infectious peritonitis in CAPD patients G Montrucchio, F Mariano, PL Cavalli, C Tetta, G Viglino, G Emanuelli, G Camussi	Kidney International	1989
Lipoproteins alter the catalytic behavior of the platelet-activating factor acetylhydrolase in human plasma DM Stafforini, ME Carter, GA Zimmerman, TM McIntyre, SM Prescott	Proceedings of the National Academy of Sciences	1989
Alveolar macrophages and eicosanoids but not neutrophils, mediate bronchoconstriction induced by FMLP in the guinea-pig MA Boukili, MF Bureau, A Lellouch-Tubiana, J Lefort, MT Simon, BB Vargaftig	British Journal of Pharmacology	1989
Platelet-activating factor and cytokine interactions in shock D Hosford, M Paubert-Braquet, P Braquet	Resuscitation	1989
Charge-related Lung Microvascular Injury SW Chang, NF Voelkel	American journal of respiratory and critical care medicine	1989
Dibutyryl-cAMP Blocks Endotoxin-induced Lung Injury in Rats SW Chang, A Sakai, NF Voelkel	American journal of respiratory and critical care medicine	1989
Beneficial effects of prostaglandin E2 in endotoxic shock are unrelated to effects on PAF-acether synthesis GC Ibbotson, JL Wallace	Prostaglandins	1989
Pentoxifylline Prevents Tumor Necrosis Factor-induced Lung Injury CM Lilly, JS Sandhu, A Ishizaka, H Harada, M Yonemaru, JW Larrick, TX Shi, PT O'Hanley, TA Raffin	American journal of respiratory and critical care medicine	1989
Southwestern Internal Medicine Conference: Adult Respiratory Distress Syndrome AR Nogare	The American Journal of the Medical Sciences	1989
Platelet-activating factor induces the production of leukotrienes by human monocytes J Fauler, G Sielhorst, JC Frölich	Biochimica et Biophysica Acta (BBA) - Molecular Cell Research	1989
Morphological analysis of changes induced in the lungs and kidneys by acetylglyceryl phosphorylcholine ester and limited by verapamil SI Svetlov, VY Burova, NV Kleimenova, AB Brydun, VL Serebryanyi, AI Matyushin, YE Vel'tishchev	Bulletin of Experimental Biology and Medicine	1989
Anesthesia and the Lung TH Stanley, RJ Sperry		1989
Lung Eicosanoid Metabolism NF Voelkel, KR Stenmark, JY Westcott, SW Chang	Clinics in Chest Medicine	1989
Platelet Activating Factor in Pulmonary Pathobiology LM McManus, SI Deavers	Clinics in Chest Medicine	1989
Interleukin 1 induces a shock-like state in rabbits. Synergism with tumor necrosis factor and the effect of cyclooxygenase inhibition S Okusawa, JA Gelfand, T Ikejima, RJ Connolly, CA Dinarello	Journal of Clinical Investigation	1988
Bowel necrosis induced by tumor necrosis factor in rats is mediated by platelet-activating factor XM Sun, W Hsueh	Journal of Clinical Investigation	1988
Hydrogen peroxide stimulates the synthesis of platelet-activating factor by endothelium and induces endothelial cell-dependent neutrophil adhesion MS Lewis, RE Whatley, P Cain, TM McIntyre, SM Prescott, GA Zimmerman	Journal of Clinical Investigation	1988
Biochemical, physiological and clinical aspects of endotoxemia NC Olson, WL Salzer, CE McCall	Molecular Aspects of Medicine	1988
Inhibitory effect of oral WEB 2086, a novel selective PAF-acether antagonist, on ex vivo platelet aggregation WS Admaus, H Heuer, CJ Meade, G Frey, HM Brecht	European Journal of Clinical Pharmacology	1988
Cobra venom factor, an activator of the complement system, enhances the bowel necrosis induced by platelet-activating factor E Llausas-Magana, W Hsueh, CM Arroyave, JL Arroyave, G Torre-Amione, F Gonzalez-Crussi	Immunopharmacology	1988
Tumor Necrosis Factor Causes Increased Pulmonary Permeability and Edema: Comparison to Septic Acute Lung Injury KE Stephens, A Ishizaka, JW Larrick, TA Raffin	American journal of respiratory and critical care medicine	1988
The effects of endotoxin on platelet-activating factor synthesis in cultured rat glomerular mesangial cells J Wang, M Kester, MJ Dunn	Biochimica et Biophysica Acta (BBA) - Molecular Cell Research	1988
Platelet activating factor: a potent constrictor of cerebral arterioles in newborn pigs WM Armstead, M Pourcyrous, R Mirro, CW Leffler, DW Busija	Circulation research	1988
Der Internist E Buchborn, M Classen, W Dölle, R Gross, J van de Loo, G Riecker, PC Scriba, W Siegenthaler, P von Wichert	Der Internist	1988
Eicosanoids in the Cardiovascular and Renal Systems PV Halushka, DE Mais		1988
Synthesis and release of platelet-activating factor by human vascular endothelial cells treated with tumor necrosis factor or interleukin 1 alpha F Bussolino, G Camussi, C Baglioni	The Journal of biological chemistry	1988
The Inflammatory Theory of Asthma L Borish	Immunological Investigations	1987
Tumor necrosis factor/cachectin stimulates peritoneal macrophages, polymorphonuclear neutrophils, and vascular endothelial cells to synthesize and release platelet-activating factor G Camussi, F Bussolino, G Salvidio, C Baglioni	Journal of Experimental Medicine	1987
PAF antagonists: different effects on platelets, neutrophils, guinea pig ileum and PAF-induced vasolidation in isolated rat lung NF Voelkel, SW Chang, KD Pfeffer, SG Worthen, IF McMurtry, PM Henson	Prostaglandins	1986
Immunology for Surgeons JE Castro		1976

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