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Research Article Free access | 10.1172/JCI111779

N-acetyl endorphin in rat spermatogonia and primary spermatocytes.

M C Cheng, J A Clements, A I Smith, S J Lolait, and J W Funder

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Published March 1, 1985 - More info

Published in Volume 75, Issue 3 on March 1, 1985
J Clin Invest. 1985;75(3):832–835. https://doi.org/10.1172/JCI111779.
© 1985 The American Society for Clinical Investigation
Published March 1, 1985 - Version history
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Abstract

In previous reports modest levels of beta-endorphin have been found by radioimmunoassay in rat testis, and localized by immunofluorescence to the interstitial cells. We have confirmed these previous reports and extended them by showing that the majority of testicular endorphins are acetylated forms, N-acetyl gamma-endorphin, N-acetyl alpha-endorphin, and N-acetyl beta-endorphin1-27. In addition, N-acetylated endorphins are not found in interstitial cells, but are confined to spermatogonia and primary spermatocytes.

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