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Citations to this article

Structural-functional relationships in diabetic nephropathy.
S M Mauer, … , D M Brown, F C Goetz
S M Mauer, … , D M Brown, F C Goetz
Published October 1, 1984
Citation Information: J Clin Invest. 1984;74(4):1143-1155. https://doi.org/10.1172/JCI111523.
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Research Article Article has an altmetric score of 12

Structural-functional relationships in diabetic nephropathy.

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Abstract

Renal biopsies in 45 patients with insulin-dependent diabetes mellitus (IDDM) were examined by semiquantitative light microscopy and quantitative electron microscopic stereologic morphometry. In these 14 males and 31 females, aged 13-52 yr, who had had IDDM for 2.5-29 yr there was no strong relationship between either glomerular basement membrane (GBM) thickness or mesangial expansion and duration of IDDM. There was only a weak relationship between the thickness of the GBM and expansion of the mesangium. Thus, GBM thickening and mesangial expansion in IDDM occur at rates that often differ from one another and that vary greatly among patients. The clinical manifestations of diabetic nephropathy, albuminuria, hypertension, and decreased glomerular filtration rate related poorly or not at all to GBM thickening. In contrast, all light and electron microscopic measures of mesangial expansion were strongly related to the clinical manifestations of diabetic nephropathy, although in the absence of these clinical findings, it was not possible to predict the severity of any of the diabetic glomerular lesions. Mesangial expansion had strong inverse correlations with capillary filtering surface area density. It is hypothesized that mesangial expansion could lead to glomerular functional deterioration in IDDM by restricting the glomerular capillary vasculature and its filtering surface. However, capillary closure, glomerular sclerosis, and interstitial fibrosis could also contribute to the clinical manifestations of this disorder.

Authors

S M Mauer, M W Steffes, E N Ellis, D E Sutherland, D M Brown, F C Goetz

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ML Sheu, CC Shen, JR Jheng, CK Chiang
Oncotarget 2017
Mitochondrial Reactive Oxygen Species and Kidney Hypoxia in the Development of Diabetic Nephropathy
TA Schiffer, M Friederich-Persson
Frontiers in physiology 2017
Insights into Diabetic Kidney Disease Using Urinary Proteomics and Bioinformatics
JA Van, JW Scholey, A Konvalinka
Journal of the American Society of Nephrology : JASN 2017
Meprin Metalloprotease Deficiency Associated with Higher Mortality Rates and More Severe Diabetic Kidney Injury in Mice with STZ-Induced Type 1 Diabetes
JE Bylander, F Ahmed, SM Conley, JM Mwiza, EM Ongeri
Journal of Diabetes Research 2017
Effects of Averrhoa carambola L. (Oxalidaceae) juice mediated on hyperglycemia, hyperlipidemia, and its influence on regulatory protein expression in the injured kidneys of streptozotocin-induced diabetic mice
Hoa Thi Thai Pham, Wansu Huang, Chuangye Han, Juman Li, Qiuqiao Xie, Jinbin Wei, Xiaohui Xu, Zefeng Lai, Xiang Huang, Renbin Huang, Qingwei Wen
American journal of translational research 2017
White blood cell fractions correlate with lesions of diabetic kidney disease and predict loss of kidney function in Type 2 diabetes
KM Wheelock, PJ Saulnier, SK Tanamas, P Vijayakumar, EJ Weil, HC Looker, RL Hanson, KV Lemley, B Yee, WC Knowler, S Hadjadj, B Najafian, M Mauer, RG Nelson
Nephrology Dialysis Transplantation 2017
Iminosugars Spiro-Linked with Morpholine-Fused 1,2,3-Triazole: Synthesis, Conformational Analysis, Glycosidase Inhibitory Activity, Antifungal Assay, and Docking Studies
SR Chavan, KS Gavale, A Khan, R Joshi, N Kumbhar, D Chakravarty, DD Dhavale
ACS Omega 2017
The promotion of nephropathy by Porphyromonas gingivalis lipopolysaccharide via toll-like receptors
K Kajiwara, S Takata, TT To, K Takara, Y Hatakeyama, S Tamaoki, RP Darveau, H Ishikawa, Y Sawa
Diabetology & metabolic syndrome 2017
Circulating fibronectin contributes to mesangial expansion in a murine model of type 1 diabetes
V Klemis, H Ghura, G Federico, C Würfel, A Bentmann, N Gretz, T Miyazaki, HJ Gröne, IA Nakchbandi
Kidney International 2017
Effect of the administration of Solanum nigrum fruit on prevention of diabetic nephropathy in streptozotocin-induced diabetic rats
F Azarkish, K Hashemi, A Talebi, M Kamalinejad, N Soltani, N Pouladian
Pharmacognosy research 2017
Diabetes and CKD in the United States Population, 2009–2014
LR Zelnick, NS Weiss, BR Kestenbaum, C Robinson-Cohen, PJ Heagerty, K Tuttle, YN Hall, IB Hirsch, IH de Boer
Clinical journal of the American Society of Nephrology : CJASN 2017
NADPH Oxidase Nox5 Accelerates Renal Injury in Diabetic Nephropathy
JC Jha, C Banal, J Okabe, SP Gray, T Hettige, BS Chow, V Thallas-Bonke, LD Vos, CE Holterman, MT Coughlan, DA Power, A Skene, EI Ekinci, ME Cooper, RM Touyz, CR Kennedy, K Jandeleit-Dahm
Diabetes 2017
Triptolide prevents extracellular matrix accumulation in experimental diabetic kidney disease by targeting microRNA-137/Notch1 pathway
F Han, S Wang, Y Chang, C Li, J Yang, Z Han, B Chang, B Sun, L Chen
Journal of Cellular Physiology 2017
Arteriolar Hyalinosis Predicts Increase in Albuminuria and GFR Decline in Normo- and Microalbuminuric Japanese Patients With Type 2 Diabetes
T Moriya, K Omura, M Matsubara, Y Yoshida, K Hayama, M Ouchi
Diabetes care 2017
Angiotensin-converting enzyme-inhibitor therapy in adolescents with type 1 diabetes in a regional cohort: Auckland, New Zealand from 2006 to 2016: Complications of type 1 diabetes
RJ Hornung, PW Reed, F Mouat, C Jefferies, AJ Gunn, PL Hofman
Journal of Paediatrics and Child Health 2017
Samchuleum attenuates diabetic renal injury through the regulation of TGF‑β/Smad signaling in human renal mesangial cells
J Yoon, Y Lee, S Namgung, B Han, E Choi, D Kang, H Lee
Molecular medicine reports 2017
Role of IGFBP7 in Diabetic Nephropathy: TGF-β1 Induces IGFBP7 via Smad2/4 in Human Renal Proximal Tubular Epithelial Cells
J Watanabe, Y Takiyama, J Honjyo, Y Makino, Y Fujita, M Tateno, M Haneda, SR Singh
PloS one 2016
Diabetic nephropathy in type 1 diabetes: a review of early natural history, pathogenesis, and diagnosis: Diabetic Nephropathy in Type 1 Diabetes
N Papadopoulou-Marketou, GP Chrousos, C Kanaka-Gantenbein
Diabetes/Metabolism Research and Reviews 2016
Diabetes and Kidney Disease: Role of Oxidative Stress
JC Jha, C Banal, BS Chow, ME Cooper, K Jandeleit-Dahm
Antioxidants & Redox Signaling 2016
Podocytes: the Weakest Link in Diabetic Kidney Disease?
JS Lin, K Susztak
Current Diabetes Reports 2016
TGF-β: the connecting link between nephropathy and fibrosis
B Sutariya, D Jhonsa, MN Saraf
Immunopharmacology and Immunotoxicology 2016
Novel Plasminogen Activator Inhibitor-1 Inhibitors Prevent Diabetic Kidney Injury in a Mouse Model
BY Jeong, MJ Uddin, JH Park, JH Lee, HB Lee, T Miyata, H Ha, S Maeda
PloS one 2016
TRPC6 channel activation promotes neonatal glomerular mesangial cell apoptosis via calcineurin/NFAT and FasL/Fas signaling pathways
H Soni, A Adebiyi
Scientific Reports 2016
MicroRNA-130b improves renal tubulointerstitial fibrosis via repression of Snail-induced epithelial-mesenchymal transition in diabetic nephropathy
X Bai, J Geng, Z Zhou, J Tian, X Li
Scientific Reports 2016
Macrophages in diabetic nephropathy in patients with type 2 diabetes
CQ Klessens, M Zandbergen, R Wolterbeek, JA Bruijn, TJ Rabelink, IM Bajema, DH IJpelaar
Nephrology Dialysis Transplantation 2016
Endocrinology: Adult and Pediatric
M Gurnell, TJ Visser, P Beck-Peccoz, VK Chatterjee
Endocrinology: Adult and Pediatric 2016
Cardiovascular autonomic neuropathy associates with nephropathy lesions in American Indians with type 2 diabetes
KM Wheelock, M Jaiswal, CL Martin, GD Fufaa, EJ Weil, KV Lemley, B Yee, E Feldman, FC Brosius, WC Knowler, RG Nelson, R Pop-Busui
Journal of Diabetes and its Complications 2016
Structural Predictors of Loss of Renal Function in American Indians with Type 2 Diabetes
GD Fufaa, EJ Weil, KV Lemley, WC Knowler, FC Brosius, B Yee, M Mauer, RG Nelson
Clinical journal of the American Society of Nephrology : CJASN 2016
Astragaloside IV ameliorates renal injury in db/db mice
H Sun, W Wang, P Han, M Shao, G Song, H Du, T Yi, S Li
Scientific Reports 2016
Antioxidative and renoprotective effects of residue polysaccharides from Flammulina velutipes
L Lin, F Cui, J Zhang, X Gao, M Zhou, N Xu, H Zhao, M Liu, C Zhang, L Jia
Carbohydrate Polymers 2016
Structural Predictors of Renal Function Decline
SB Nicholas
Clinical journal of the American Society of Nephrology : CJASN 2016
Diabetische Nierenerkrankung – Update 2016: Positionspapier der Österreichischen Diabetes Gesellschaft und der Österreichischen Gesellschaft für Nephrologie
H Sourij, R Edlinger, F Prischl, M Auinger, A Kautzky-Willer, MD Säemann, R Prager, M Clodi, G Schernthaner, G Mayer, R Oberbauer, AR Rosenkranz
Wiener klinische Wochenschrift 2016
Tributyltin chloride induces renal dysfunction by inflammation and oxidative stress in female rats
JV Coutinho, LC Freitas-Lima, FF Freitas, FP Freitas, PL Podratz, RP Magnago, ML Porto, SS Meyrelles, EC Vasquez, PA Brandão, MT Carneiro, FD Paiva-Melo, L Miranda-Alves, IV Silva, AL Gava, JB Graceli
Toxicology Letters 2016
Evaluation of Netrin-1 Levels and Albuminuria in Patients With Diabetes: Netrin-1 Levels in Diabetic Nephropathy
E Ay, K Marakoğlu, M Kizmaz, A Ünlü
Journal of Clinical Laboratory Analysis 2016
Silent diabetic nephropathy
SM Said, SH Nasr
Kidney International 2016
Prognostic Value of Tubulointerstitial Lesions, Urinary N-Acetyl- -D-Glucosaminidase, and Urinary  2-Microglobulin in Patients with Type 2 Diabetes and Biopsy-Proven Diabetic Nephropathy
K Mise, J Hoshino, T Ueno, R Hazue, J Hasegawa, A Sekine, K Sumida, R Hiramatsu, E Hasegawa, M Yamanouchi, N Hayami, T Suwabe, N Sawa, T Fujii, S Hara, K Ohashi, K Takaichi, Y Ubara
Clinical journal of the American Society of Nephrology : CJASN 2016
Early detection of diabetic kidney disease: Present limitations and future perspectives
CH Lin, YC Chang, LM Chuang
World journal of diabetes 2016
Monoclonal Antibody Pharmacokinetics in Type 2 Diabetes Mellitus and Diabetic Nephropathy
GS Chadha, ME Morris
Current Pharmacology Reports 2016
Cytokines and T Helper Cells in Diabetic Nephropathy Pathogenesis
LS Araújo, MV da Silva, CA da Silva, ML Monteiro, LH de Pereira, LP Rocha, RR Corrêa, MA Reis, JR Machado
Journal of Diabetes Mellitus 2016
Endocrinology
C Napier, SH Pearce
Endocrinology 2016
Dietary low-fat soy milk powder retards diabetic nephropathy progression via inhibition of renal fibrosis and renal inflammation
HF Jheng, M Hirotsuka, T Goto, M Shibata, Y Matsumura, T Kawada
Molecular Nutrition & Food Research 2016
Advanced Glycation End Products Predict Loss of Renal Function and Correlate With Lesions of Diabetic Kidney Disease in American Indians With Type 2 Diabetes
PJ Saulnier, KM Wheelock, S Howell, EJ Weil, SK Tanamas, WC Knowler, KV Lemley, M Mauer, B Yee, RG Nelson, PJ Beisswenger
Diabetes 2016
Rodent models of diabetic nephropathy: their utility and limitations
M Kitada, Y Ogura, D Koya
International journal of nephrology and renovascular disease 2016
H 2 S improves renal fibrosis in STZ-induced diabetic rats by ameliorating TGF- β 1 expression
Y Li, L Li, O Zeng, JM Liu, J Yang
Renal Failure 2016
Diabetic Kidney Disease
Victoria E Bouhairie, Janet B McGill
Missouri Medicine 2016
Bone Morphogenetic Protein 4 and Smad1 Mediate Extracellular Matrix Production in the Development of Diabetic Nephropathy
T Matsubara, M Araki, H Abe, O Ueda, K Jishage, A Mima, C Goto, T Tominaga, M Kinosaki, S Kishi, K Nagai, N Iehara, N Fukushima, T Kita, H Arai, T Doi
Diabetes 2015
New developments concerning the proximal tubule in diabetic nephropathy: in vitro models and mechanisms
J Slyne, C Slattery, T McMorrow, MP Ryan
Nephrology Dialysis Transplantation 2015
TGF-β/BMP proteins as Therapeutic Targets in Renal Fibrosis. Where have we arrived after 25 years of trials and tribulations?
JM Muñoz-Félix, M González-Núñez, C Martínez-Salgado, JM López-Novoa
Pharmacology & Therapeutics 2015
Treatment of chronic kidney diseases with histone deacetylase inhibitors
N Liu, S Zhuang
Frontiers in physiology 2015
Diabetic kidney disease
MC Thomas, M Brownlee, K Susztak, K Sharma, KA Jandeleit-Dahm, S Zoungas, P Rossing, PH Groop, ME Cooper
Nature Reviews Disease Primers 2015
Diabetic Kidney Disease: A Syndrome Rather Than a Single Disease
GB Piccoli, G Grassi, G Cabiddu, M Nazha, S Roggero, I Capizzi, AD Pascale, AM Priola, CD Vico, S Maxia, V Loi, AM Asunis, A Pani, A Veltri
The review of diabetic studies : RDS 2015
Phoenix dactylifera seeds ameliorate early diabetic complications in streptozotocin-induced diabetic rats
DH Abdelaziz, SA Ali, MM Mostafa
Pharmaceutical Biology 2015
Screening and Treatment by the Primary Care Provider of Common Diabetes Complications
MP Gilbert
Medical Clinics of North America 2015
Association of single nucleotide polymorphisms in the gene encoding GLUT1 and diabetic nephropathy in Brazilian patients with type 1 diabetes mellitus
T Marques, TA Patente, MB Monteiro, AM Cavaleiro, MS Queiroz, M Nery, MJ Azevedo, LH Canani, MC Parisi, A Moura-Neto, M Passarelli, D Giannella-Neto, UF Machado, ML Corrêa-Giannella
Clinica Chimica Acta 2015
Early-Onset Diabetic E1-DN Mice Develop Albuminuria and Glomerular Injury Typical of Diabetic Nephropathy
ME Hyvönen, V Dumont, J Tienari, E Lehtonen, J Ustinov, M Havana, H Jalanko, T Otonkoski, PJ Miettinen, S Lehtonen
BioMed Research International 2015
Recent advances in glucose-lowering treatment to reduce diabetic kidney disease
NM Hanssen, N Russell, ME Cooper
Expert Opinion on Pharmacotherapy 2015
Reno-protection of G004, a novel anti-diabetic sulfonylurea in db/db mice
X Tong, H Ma, SW Amadi, L Ma, G Wu
Naunyn-Schmiedeberg's Archives of Pharmacology 2015
Fluorofenidone protects against renal fibrosis by inhibiting STAT3 tyrosine phosphorylation
J Tang, C Liu, M Lu, J Zhang, W Mei, W Yang, Y Xie, L Huang, Z Peng, Q Yuan, J Liu, G Hu, L Tao
Molecular and Cellular Biochemistry 2015
MicroRNA-26a inhibits TGF-β-induced extracellular matrix protein expression in podocytes by targeting CTGF and is downregulated in diabetic nephropathy
K Koga, H Yokoi, K Mori, M Kasahara, T Kuwabara, H Imamaki, A Ishii, KP Mori, Y Kato, S Ohno, N Toda, MA Saleem, A Sugawara, K Nakao, M Yanagita, M Mukoyama
Diabetologia 2015
Podocyte Structural Parameters Do Not Predict Progression to Diabetic Nephropathy in Normoalbuminuric Type 1 Diabetic Patients
T Harindhanavudhi, A Parks, M Mauer, ML Caramori
American Journal of Nephrology 2015
Chronic Renal Disease
P Delanaye, AD Rule
2015
Combined effect of hydrogen sulphide donor and losartan in experimental diabetic nephropathy in rats
M Kaur, S Sachdeva, O Bedi, T Kaur, P Kumar
Journal of Diabetes & Metabolic Disorders 2015
Coffee in Health and Disease Prevention
NP Ulrih
Coffee in Health and Disease Prevention 2015
Circulating TGF-β1-regulated miRNAs and the risk of rapid progression to ESRD in type 1 diabetes
MG Pezzolesi, E Satake, KP McDonnell, M Major, AM Smiles, AS Krolewski
Diabetes 2015
International Textbook of Diabetes Mellitus: DeFronzo/International Textbook of Diabetes Mellitus, Fourth Edition
RN Bergman, M Ader
International Textbook of Diabetes Mellitus: DeFronzo/International Textbook of Diabetes Mellitus, Fourth Edition 2015
Tumor necrosis factor receptors 1 and 2 are associated with early glomerular lesions in type 2 diabetes
ME Pavkov, EJ Weil, GD Fufaa, RG Nelson, KV Lemley, WC Knowler, MA Niewczas, AS Krolewski
Kidney International 2015
Diabetic nephropathy: What does the future hold?
RM Montero, A Covic, L Gnudi, D Goldsmith
International Urology and Nephrology 2015
Association of HaeIII single nucleotide polymorphisms in the SLC2A1 gene with risk of diabetic nephropathy; evidence from Kurdish patients with type 2 diabetes mellitus
S Amini, M Javanmardi, A Mokarizadeh, F Maroofi, C Jalali, NA Azadi, H Mohammadi, M Abdi
QJM 2015
Renal glomerular dysfunction in relation to retinal arteriolar narrowing and high pulse pressure in seniors
YM Gu, T Petit, FF Wei, L Thijs, L Jacobs, ZY Zhang, WY Yang, N Cauwenberghs, J Knez, HA Struijker-Boudier, T Kuznetsova, P Verhamme, JA Staessen
Hypertension Research 2015
Different localization and expression of protein kinase C-beta in kidney cortex of diabetic nephropathy mice and its role in telmisartan treatment
Jianqing Wang, Fu Qin, Anguo Deng, Lijun Yao
American journal of translational research 2015
Drug Targets for Oxidative Podocyte Injury in Diabetic Nephropathy
AB Bhatti, M Usman
Cureus 2015
The Value of Serum Prolidase Activity in Progression of Microalbuminuria in Patients With Type 2 Diabetes Mellitus: Prolidase Activity in Microalbuminuria
T Sabuncu, O Boduroglu, MA Eren, AN Torun, N Aksoy
Journal of Clinical Laboratory Analysis 2015
Histological changes of kidney in diabetic nephropathy
Mohsen Pourghasem, Hamid Shafi, Zahra Babazadeh
Caspian Journal of Internal Medicine 2015
The impact of hyperfiltration on the diabetic kidney
E Premaratne, S Verma, EI Ekinci, G Theverkalam, G Jerums, RJ MacIsaac
Diabetes & Metabolism 2014
Implications of polyadenylation in health and disease
A Curinha, SO Braz, I Pereira-Castro, A Cruz, A Moreira
Nucleus 2014
Molecular and Cellular Events Mediating Glomerular Podocyte Dysfunction and Depletion in Diabetes Mellitus
PA Kumar, GI Welsh, MA Saleem, RK Menon
Frontiers in Endocrinology 2014
The endothelium in diabetic nephropathy
RE Gilbert
Current Atherosclerosis Reports 2014
Mesenchymal Stem Cell-Based Treatment for Microvascular and Secondary Complications of Diabetes Mellitus
GC Davey, SB Patil, A O’Loughlin, T O’Brien
Frontiers in Endocrinology 2014
Laminin α1 Regulates Age-Related Mesangial Cell Proliferation and Mesangial Matrix Accumulation through the TGF-β Pathway
L Ning, H Kurihara, S Vega, N Ichikawa-Tomikawa, Z Xu, R Nonaka, S Kazuno, Y Yamada, JH Miner, E Arikawa-Hirasawa
The American Journal of Pathology 2014
Nitric oxide donors rescue diabetic nephropathy through oxidative-stress- and nitrosative-stress-mediated Wnt signaling pathways
YC Hsu, PH Lee, CC Lei, C Ho, YH Shih, CL Lin
Journal of Diabetes Investigation 2014
Diabetic kidney disease in children and adolescents
M Afkarian
Pediatric Nephrology 2014
Changes in the pharmacokinetic of sildenafil citrate in rats with Streptozotocin-induced diabetic nephropathy
AS Tripathi, PM Mazumder, AV Chandewar
Journal of Diabetes & Metabolic Disorders 2014
Is diabetic nephropathy reversible?
P Fioretto, I Barzon, M Mauer
Diabetes Research and Clinical Practice 2014
Molecular Mechanisms Underlying the Nephroprotective Effects of PACAP in Diabetes
E Banki, K Kovacs, D Nagy, T Juhasz, P Degrell, K Csanaky, P Kiss, G Jancso, G Toth, A Tamas, D Reglodi
Journal of Molecular Neuroscience 2014
Netrin-1, a urinary proximal tubular injury marker, is elevated early in the time course of human diabetes
C Jayakumar, FL Nauta, SJ Bakker, H Bilo, RT Gansevoort, MH Johnson, G Ramesh
Journal of Nephrology 2014
Nephro-protective effect of granulocyte colony-stimulating factor in streptozotocin induced diabetic rats
O Erbas, H Yapislar, F Oltulu, A Yavasoğlu, H Aktug, D Taskiran
Biotechnic & Histochemistry 2014
‘Progressive diabetic nephropathy. How useful is microalbuminuria?: contra’
RJ MacIsaac, EI Ekinci, G Jerums
Kidney International 2014
Novel Therapies for Diabetic Kidney Disease
RZ Alicic, KR Tuttle
Advances in Chronic Kidney Disease 2014
Long-term outcomes after organ transplantation in diabetic end-stage renal disease
JP Lindahl, T Jenssen, A Hartmann
Diabetes Research and Clinical Practice 2014
In patients with type 1 diabetes simultaneous pancreas and kidney transplantation preserves long-term kidney graft ultrastructure and function better than transplantation of kidney alone
JP Lindahl, FP Reinholt, IA Eide, A Hartmann, K Midtvedt, H Holdaas, LT Dorg, TM Reine, SO Kolset, R Horneland, O Øyen, K Brabrand, T Jenssen
Diabetologia 2014
Renal histology in diabetic nephropathy: A novel perspective
M Sahay, RK Mahankali, K Ismal, PS Vali, RK Sahay, G Swarnalata
Indian journal of nephrology 2014
Chaihuang-Yishen Granule Inhibits Diabetic Kidney Disease in Rats through Blocking TGF-β/Smad3 Signaling
TT Zhao, HJ Zhang, XG Lu, XR Huang, WK Zhang, H Wang, HY Lan, P Li, H Abe
PloS one 2014
Glomerular structural-functional relationship models of diabetic nephropathy are robust in type 1 diabetic patients
M Mauer, ML Caramori, P Fioretto, B Najafian
Nephrology Dialysis Transplantation 2014
Histopathological analyses of diabetic nephropathy in sucrose-fed Otsuka Long-Evans Tokushima fatty rats
JH Shin, BI So, YS Song, Y Lee, KS Jang, H Kim, KS Kim
Endocrine Research 2014
Renal histological heterogeneity and functional progress in normoalbuminuric and microalbuminuric Japanese patients with type 2 diabetes
T Moriya, Y Suzuki, S Inomata, M Iwano, M Kanauchi, M Haneda
BMJ Open Diabetes Research & Care 2014
Synergistic Effects of Leflunomide and Benazepril in Streptozotocin-Induced Diabetic Nephropathy
H Jin, SG Piao, JZ Jin, YS Jin, ZH Cui, HF Jin, HL Zheng, JJ Li, YJ Jiang, CW Yang, C Li
Nephron Experimental Nephrology 2014
Current clinical problems of diabetic nephropathy and novel approach from basic study
T Doi
Nihon Shoni Jinzobyo Gakkai Zasshi 2014
Pathobiology of Human Disease
S Akilesh
Pathobiology of Human Disease 2014
Textbook of Organ Transplantation
J Stehlik, MS Kiernan, D Budge, MR Johnson
Textbook of Organ Transplantation 2014
A Glimpse of Matrix Metalloproteinases in Diabetic Nephropathy
X. Xu, L. Xiao, P. Xiao, S. Yang, G. Chen, F. Liu, Y.Y. Kanwar, L. Sun
Current medicinal chemistry 2014
Role of caveolae in high glucose and TGF-β1 induced fibronectin production in rat mesangial cells
Yuantao Liu, Shengxia Lu, Yuchao Zhang, Xiangdong Wang, Feng Kong, Ye Liu, Li Peng, Yuqin Fu
International journal of clinical and experimental pathology 2014
Expression of Toll-Like Receptor 2 in Glomerular Endothelial Cells and Promotion of Diabetic Nephropathy by Porphyromonas gingivalis Lipopolysaccharide
Y Sawa, S Takata, Y Hatakeyama, H Ishikawa, E Tsuruga, T Wang
PloS one 2014
Role of the TGFβ/p65 pathway in tanshinone IIA-treated HBZY-1 cells
G Chen, X Zhang, C Li, Y Lin, YU MENG, S Tang
Molecular medicine reports 2014
Diabetes and Kidney Disease
EV Lerma, V Batuman
2014
Intensive glucose control versus conventional glucose control for type 1 diabetes mellitus
B Fullerton, K Jeitler, M Seitz, K Horvath, A Berghold, A Siebenhofer
Cochrane Database of Systematic Reviews 2014
Expression of Toll-Like Receptor 4 in Glomerular Endothelial Cells under Diabetic Conditions
S Takata, Y Sawa, T Uchiyama, H Ishikawa
ACTA HISTOCHEMICA ET CYTOCHEMICA 2013
Progressive renal decline as the major feature of diabetic nephropathy in type 1 diabetes
AS Krolewski, T Gohda, MA Niewczas
Clinical and Experimental Nephrology 2013
Temporal Profile of Diabetic Nephropathy Pathologic Changes
C Ponchiardi, M Mauer, B Najafian
Current Diabetes Reports 2013
Korean red ginseng extract alleviates advanced glycation end product-mediated renal injury
HY Quan, DY Kim, SH Chung
Journal of Ginseng Research 2013
Seldin and Giebisch's The Kidney
CJ Cooper, LD Dworkin, WL Henrich
Seldin and Giebisch's The Kidney 2013
Receptor for advanced glycation end-products promotes premature senescence of proximal tubular epithelial cells via activation of endoplasmic reticulum stress-dependent p21 signaling
J Liu, K Huang, GY Cai, XM Chen, JR Yang, LR Lin, J Yang, BG Huo, J Zhan, YN He
Cellular Signalling 2013
Tubular injury marker netrin-1 is elevated early in experimental diabetes
JJ White, R Mohamed, C Jayakumar, G Ramesh
Journal of Nephrology 2013
Elevated transcriptional co-activator p102 mediates angiotensin II type 1 receptor up-regulation and extracellular matrix overproduction in the high glucose-treated rat glomerular mesangial cells and isolated glomeruli
Z Wang, J Ni, D Shao, J Liu, Y Shen, L Zhou, Y Huang, C Yu, J Wang, H Xue, L Lu
European Journal of Pharmacology 2013
Modeling albuminuria in type 2 diabetes: a second look
JT Lane, JA Stoner
Translational Research 2013
Molecular mechanisms in the pathogenesis of diabetic nephropathy: An update
MK Arora, UK Singh
Vascular Pharmacology 2013
The Renal Endothelium in Diabetic Nephropathy
T Eleftheriadis, G Antoniadi, G Pissas, V Liakopoulos, I Stefanidis
Renal Failure 2013
Effect of 2-dodecyl-6-methoxycyclohexa-2,5-diene-1,4-dione, isolated from Averrhoa carambola L. (Oxalidaceae) roots, on advanced glycation end-product-mediated renal injury in type 2 diabetic KKAy mice
Ni Zheng, Xing Lin, Qingwei Wen, Kintoko, Shijun Zhang, Jianchun Huang, Xiaohui Xu, Renbin Huang
Toxicology Letters 2013
Report on ISN Forefronts, Melbourne, Australia, 4–7 October 2012: tubulointerstitial disease in diabetic nephropathy
JM Forbes, DC Harris, ME Cooper
Kidney International 2013
Kidney: Toxicological Assessment
D Choi, W Jung, I Cho, M Joo, C Lee, S Lim
Kidney: Toxicological Assessment 2013
Comparative investigation of kidney mesangial cells from increased oxidative stress-induced diabetic rats by using different microscopy techniques
AK Sargin, B Can, B Turan
Molecular and Cellular Biochemistry 2013
Glyoxalase-1 overexpression reduces endothelial dysfunction and attenuates early renal impairment in a rat model of diabetes
O Brouwers, PM Niessen, T Miyata, JA Østergaard, A Flyvbjerg, CJ Peutz-Kootstra, J Sieber, PH Mundel, M Brownlee, BJ Janssen, JG Mey, CD Stehouwer, CG Schalkwijk
Diabetologia 2013
Relationship between serum transforming growth factor β 1 concentrations and the duration of type 1 diabetes mellitus in children and adolescents
K Zorena, D Raczyńska, P Wiśniewski, E Malinowska, M Myśliwiec, K Raczyńska, D Rachoń
Mediators of Inflammation 2013
The Extract of Litsea japonica Reduced the Development of Diabetic Nephropathy via the Inhibition of Advanced Glycation End Products Accumulation in db/db Mice
E Sohn, J Kim, CS Kim, YM Lee, K Jo, SD Shin, JH Kim, JS Kim
Evidence-Based Complementary and Alternative Medicine 2013
Emodin attenuates high glucose-induced TGF-β1 and fibronectin expression in mesangial cells through inhibition of NF-κB pathway
J Yang, Z Zeng, T Wu, Z Yang, B Liu, T Lan
Experimental Cell Research 2013
Diabetes and kidney disease
U Lingaraj, C Annamalai, H Radhakrishnan
Apollo Medicine 2013
Renal lesions predict progression of diabetic nephropathy in type 1 diabetes
ML Caramori, A Parks, M Mauer
Journal of the American Society of Nephrology : JASN 2013
Dyslipoproteinemia and impairment of renal function in diabetic kidney disease: an analysis of animal studies, observational studies, and clinical trials
CC Hung, JC Tsai, HT Kuo, JM Chang, SJ Hwang, HC Chen
The review of diabetic studies : RDS 2013
G-CSF Prevents Progression of Diabetic Nephropathy in Rat
BI So, YS Song, CH Fang, JY Park, Y Lee, JH Shin, H Kim, KS Kim, C Chatziantoniou
PloS one 2013
Effect of losartan on prevention and progression of early diabetic nephropathy in American Indians with type 2 diabetes
EJ Weil, G Fufaa, LI Jones, T Lovato, KV Lemley, RL Hanson, WC Knowler, PH Bennett, B Yee, BD Myers, RG Nelson
Diabetes 2013
Reference Module in Chemistry, Molecular Sciences and Chemical Engineering
AN Hegde
Reference Module in Chemistry, Molecular Sciences and Chemical Engineering 2013
Long-Term Outcomes of Japanese Type 2 Diabetic Patients With Biopsy-Proven Diabetic Nephropathy
M Shimizu, K Furuichi, T Toyama, S Kitajima, A Hara, K Kitagawa, Y Iwata, N Sakai, T Takamura, M Yoshimura, H Yokoyama, S Kaneko, T Wada
Diabetes care 2013
Renal Structure in Normoalbuminuric and Albuminuric Patients With Type 2 Diabetes and Impaired Renal Function
EI Ekinci, G Jerums, A Skene, P Crammer, D Power, KY Cheong, S Panagiotopoulos, K McNeil, ST Baker, P Fioretto, RJ MacIsaac
Diabetes care 2013
Diabetic kidney disease; review of the current knowledge
Heshmatollah Shahbazian, Isa Rezaii
Journal of Renal Injury Prevention 2013
Mechanisms of Diabetic Complications
JM Forbes, ME Cooper
Physiological reviews 2013
Clinical Value of NGAL, L-FABP and Albuminuria in Predicting GFR Decline in Type 2 Diabetes Mellitus Patients
KM Chou, CC Lee, CH Chen, CY Sun, N Ashton
PloS one 2013
Plumbagin Ameliorates Diabetic Nephropathy via Interruption of Pathways that Include NOX4 Signalling
R Yong, XM Chen, S Shen, S Vijayaraj, Q Ma, CA Pollock, S Saad, D Long
PloS one 2013
Epigallocatechin-3-gallate combined with alpha lipoic acid attenuates high glucose-induced receptor for advanced glycation end products (RAGE) expression in human embryonic kidney cells
JG Leu, CY Lin, JH Jian, CY Shih, YJ Liang
Anais da Academia Brasileira de Ciências 2013
Fundamentals of Renal Pathology
AB Fogo, AH Cohen, RB Colvin, JC Jennette, CE Alpers
2013
Altered Dynamics in the Renal Lymphatic Circulation of Type 1 and Type 2 Diabetic Mice
T Uchiyama, S Takata, H Ishikawa, Y Sawa
ACTA HISTOCHEMICA ET CYTOCHEMICA 2013
Can We Target Tubular Damage to Prevent Renal Function Decline in Diabetes?
JV Bonventre
Seminars in Nephrology 2012
TGFβ modulates cell-to-cell communication in early epithelial-to-mesenchymal transition
CE Hills, E Siamantouras, SW Smith, P Cockwell, KK Liu, PE Squires
Diabetologia 2012
Scleraxis modulates bone morphogenetic protein 4 (BMP4)-Smad1 protein-smooth muscle α-actin (SMA) signal transduction in diabetic nephropathy
H Abe, T Tominaga, T Matsubara, N Abe, S Kishi, K Nagai, T Murakami, T Araoka, T Doi
The Journal of biological chemistry 2012
Catalase deficiency accelerates diabetic renal injury through peroxisomal dysfunction
I Hwang, J Lee, JY Huh, J Park, HB Lee, YS Ho, H Ha
Diabetes 2012
The Glomerular Basement Membrane as a Model System to Study the Bioactivity of Heparan Sulfate Glycosaminoglycans
KJ McCarthy, DJ Wassenhove-McCarthy
Microscopy and Microanalysis 2012
Differential expression of laminin isoforms in diabetic nephropathy and other renal diseases
S Setty, AA Michael, AJ Fish, SM Mauer, RJ Butkowski, I Virtanen, Y Kim
Modern Pathology 2012
Renal podocyte injury in a rat model of type 2 diabetes is prevented by metformin
J Kim, E Shon, CS Kim, JS Kim
Experimental Diabetes Research 2012
The role of the Janus kinase family/signal transducer and activator of transcription signaling pathway in fibrotic renal disease
F Matsui, KK Meldrum
Journal of Surgical Research 2012
Podocyte detachment and reduced glomerular capillary endothelial fenestration promote kidney disease in type 2 diabetic nephropathy
EJ Weil, KV Lemley, CC Mason, B Yee, LI Jones, K Blouch, T Lovato, M Richardson, BD Myers, RG Nelson
Kidney International 2012
Coenzyme Q10 prevents GDP-sensitive mitochondrial uncoupling, glomerular hyperfiltration and proteinuria in kidneys from db/db mice as a model of type 2 diabetes
MF Persson, S Franzén, SB Catrina, G Dallner, P Hansell, K Brismar, F Palm
Diabetologia 2012
Early-outgrowth bone marrow cells attenuate renal injury and dysfunction via an antioxidant effect in a mouse model of type 2 diabetes
Y Zhang, DA Yuen, A Advani, K Thai, SL Advani, D Kepecs, MG Kabir, KA Connelly, RE Gilbert
Diabetes 2012
Perspectives on Systems Biology Applications in Diabetic Kidney Disease
CV Komorowsky, FC 3rd, S Pennathur, M Kretzler
Journal of Cardiovascular Translational Research 2012
Phenotypic change of macrophages in the progression of diabetic nephropathy; sialoadhesin-positive activated macrophages are increased in diabetic kidney
R Nagase, N Kajitani, K Shikata, D Ogawa, R Kodera, S Okada, Y Kido, H Makino
Clinical and Experimental Nephrology 2012
Effects of Stimulation of Soluble Guanylate Cyclase on Diabetic Nephropathy in Diabetic eNOS Knockout Mice on Top of Angiotensin II Receptor Blockade
IM Ott, ML Alter, K Websky, A Kretschmer, O Tsuprykov, Y Sharkovska, K Krause-Relle, J Raila, A Henze, JP Stasch, B Hocher
PloS one 2012
Methylglyoxal, obesity, and diabetes
P Matafome, C Sena, R Seiça
Endocrine 2012
ANAEMIA, DIABETES AND CHRONIC KIDNEY DISEASE: WHERE ARE WE NOW? : ANAEMIA, DIABETES AND CHRONIC KIDNEY DISEASE: WHERE ARE WE NOW?
PE Dr.
Journal of Renal Care 2012
Brenner and Rector's The Kidney
C Brugnara, KU Eckardt
Brenner and Rector's The Kidney 2012
Downregulation of vasopressin V1A receptors and activation of mitogen-activated protein kinase in rat mesangial cells cultured under high-glucose conditions
A Tahara, J Tsukada, Y Tomura, T Yatsu, M Shibasaki
Clinical and Experimental Pharmacology and Physiology 2012
Skimmin, a coumarin, suppresses the streptozotocin-induced diabetic nephropathy in wistar rats
S Zhang, J Yang, H Li, Y Li, Y Liu, D Zhang, F Zhang, W Zhou, X Chen
European Journal of Pharmacology 2012
Polydatin ameliorates experimental diabetes-induced fibronectin through inhibiting the activation of NF-κB signaling pathway in rat glomerular mesangial cells
X Xie, J Peng, K Huang, J Huang, X Shen, P Liu, H Huang
Molecular and Cellular Endocrinology 2012
Synergetic effect of Andrographis paniculata polysaccharide on diabetic nephropathy with andrographolide
J Xu, Z Li, M Cao, H Zhang, J Sun, J Zhao, Q Zhou, Z Wu, L Yang
International Journal of Biological Macromolecules 2012
Research into the structure of the kidney glomerulus – making it count
KE White
Micron 2012
The Endothelium in Diabetic Nephropathy
A Advani, RE Gilbert
Seminars in Nephrology 2012
Diagnostic Atlas of Renal Pathology
AB Fogo, M Kashgarian
Diagnostic Atlas of Renal Pathology 2012
Human umbilical cord blood-derived mesenchymal stem cells prevent diabetic renal injury through paracrine action
JH Park, I Hwang, SH Hwang, H Han, H Ha
Diabetes Research and Clinical Practice 2012
Berberine suppresses high glucose-induced TGF-β1 and fibronectin synthesis in mesangial cells through inhibition of sphingosine kinase 1/AP-1 pathway
T Lan, W Liu, X Xie, K Huang, J Peng, J Huang, X Shen, P Liu, H Yang, H Huang
European Journal of Pharmacology 2012
Diabetes and Kidney Disease: Wolf/Diabetes and Kidney Disease
CA Böger, PR Mertens
Diabetes and Kidney Disease: Wolf/Diabetes and Kidney Disease 2012
Ezetimibe Ameliorates Early Diabetic Nephropathy in db/db Mice
Y Tamura, T Murayama, M Minami, T Matsubara, M Yokode, H Arai
Journal of Atherosclerosis and Thrombosis 2012
Morphologic Features of Declining Renal Function in Type 1 Diabetes
B Najafian, M Mauer
Seminars in Nephrology 2012
Cell Therapy for Diabetic Nephropathy: Is the Future, Now?
RE Gilbert, Y Zhang, DA Yuen
Seminars in Nephrology 2012
Role of Netrin-1 Beyond the Brain: From Biomarker of Tissue Injury to Therapy for Inflammatory Diseases
G Ramesh
Recent Patents on Biomarkers 2012
Effects of Pancreas Transplantation on the Prevention and Reversal of Diabetic Nephropathy
M Mauer, P Fioretto
The Medical clinics of North America 2012
Extract of Adenanthera pavonina L. seed reduces development of diabetic nephropathy in streptozotocin-induced diabetic rats
R Pandhare, B Sangameswaran
2012
Scleraxis Modulates Bone Morphogenetic Protein 4 (BMP4)-Smad1 Protein-Smooth Muscle α-Actin (SMA) Signal Transduction in Diabetic Nephropathy*
H Abe, T Tominaga, T Matsubara, N Abe, S Kishi, K Nagai, T Murakami, T Araoka, T Doi
The Journal of biological chemistry 2012
Extract of Adenantherapavonina L. seed reduces development of diabetic nephropathy in streptozotocin-induced diabetic rats
Ramdas Pandhare, Balakrishnan Sangameswaran
Avicenna journal of phytomedicine 2012
Hyperglycemia induces Toll like receptor 4 expression and activity in mouse mesangial cells: relevance to diabetic nephropathy
H Kaur, A Chien, I Jialal
American journal of physiology. Renal physiology 2012
Ultrastructure of a Novel Bacterial Form Located in Staphylococcus aureus In Vitro and In Vivo Catheter-Associated Biofilms
DJ Hess, MJ Henry-Stanley, AM Barnes, GM Dunny, CL Wells
Journal of Histochemistry & Cytochemistry 2012
Comprehensive Physiology
R Terjung
Comprehensive Physiology 2011
Comprehensive Physiology
R Terjung
Comprehensive Physiology 2011
Comprehensive Physiology
R Terjung
Comprehensive Physiology 2011
SOX9 Protein Induces a Chondrogenic Phenotype of Mesangial Cells and Contributes to Advanced Diabetic Nephropathy*
S Kishi, H Abe, H Akiyama, T Tominaga, T Murakami, A Mima, K Nagai, F Kishi, M Matsuura, T Matsubara, N Iehara, O Ueda, N Fukushima, K Jishage, T Doi
The Journal of biological chemistry 2011
Renoprotective antioxidant effect of alagebrium in experimental diabetes
J Park, MK Kwon, JY Huh, WJ Choi, LS Jeong, R Nagai, WY Kim, J Kim, GT Lee, HB Lee, H Ha
Nephrology Dialysis Transplantation 2011
Beneficial effects of banana (Musa sp. var. elakki bale) flower and pseudostem on hyperglycemia and advanced glycation end-products (AGEs) in streptozotocin-induced diabetic rats
JJ Bhaskar, MS Shobha, K Sambaiah, PV Salimath
Journal of Physiology and Biochemistry 2011
Diabetische Nephropathie
J Menne, H Haller
Der Internist 2011
The effect of dehydroepiandrosterone (DHEA) on renal function and metabolism in diabetic rats
MP Jahn, LF Gomes, MH Jacob, DR Janner, AS da Araújo, A Belló-Klein, MF Ribeiro, LC Kucharski
Steroids 2011
Role of oxidized low density lipoproteins and free fatty acids in the pathogenesis of glomerulopathy and tubulointerstitial lesions in type 2 diabetes
R Nosadini, G Tonolo
Nutrition, Metabolism and Cardiovascular Diseases 2011
Association of Urinary Type IV Collagen With GFR Decline in Young Patients With Type 1 Diabetes
M Morita, Y Uchigata, K Hanai, Y Ogawa, Y Iwamoto
American Journal of Kidney Diseases 2011
Regulation of heparanase by albumin and advanced glycation end products in proximal tubular cells
V Masola, G Gambaro, E Tibaldi, M Onisto, C Abaterusso, A Lupo
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 2011
Bardoxolone Methyl and Kidney Function in CKD with Type 2 Diabetes
PE Pergola, P Raskin, RD Toto, CJ Meyer, JW Huff, EB Grossman, M Krauth, S Ruiz, P Audhya, H Christ-Schmidt, J Wittes, DG Warnock
New England Journal of Medicine 2011
The role of TGF-β and epithelial-to mesenchymal transition in diabetic nephropathy
CE Hills, PE Squires
Cytokine & Growth Factor Reviews 2011
Anti-diabetic effect of pyroglutamic acid in type 2 diabetic Goto-Kakizaki rats and KK- A y mice
O Yoshinari, K Igarashi
British Journal of Nutrition 2011
The protective effect of Salvia miltiorrhiza in an animal model of early experimentally induced diabetic nephropathy
SH Lee, YS Kim, SJ Lee, BC Lee
Journal of Ethnopharmacology 2011
Curcumin attenuates diabetic nephropathy by inhibiting PKC-α and PKC-β1 activity in streptozotocin-induced type I diabetic rats
V Soetikno, K Watanabe, FR Sari, M Harima, RA Thandavarayan, PT Veeraveedu, W Arozal, V Sukumaran, AP Lakshmanan, S Arumugam, K Suzuki
Molecular Nutrition & Food Research 2011
Retinal Arteriolar Narrowing and Subsequent Development of CKD Stage 3: The Multi-Ethnic Study of Atherosclerosis (MESA)
JW Yau, J Xie, R Kawasaki, H Kramer, M Shlipak, R Klein, B Klein, MF Cotch, TY Wong
American journal of kidney diseases : the official journal of the National Kidney Foundation 2011
Glomerular hyperfiltration and increased glomerular filtration surface are associated with renal function decline in normo- and microalbuminuric type 2 diabetes
T Moriya, A Tsuchiya, S Okizaki, A Hayashi, K Tanaka, M Shichiri
Kidney International 2011
Histological predictors for renal prognosis in diabetic nephropathy in diabetes mellitus type 2 patients with overt proteinuria : Histological predictors in DM nephropathy
T Okada, T Nagao, H Matsumoto, Y Nagaoka, T Wada, T Nakao
Nephrology 2011
Williams Textbook of Endocrinology
DW Cooke, SA Divall, S Radovick
Williams Textbook of Endocrinology 2011
Glomerulopatías secundarias a enfermedades sistémicas
J Rojas-Rivera, A Barat, J Egido
Medicine - Programa de Formación Médica Continuada Acreditado 2011
Evolution of Treatment for Diabetic Nephropathy: Historical Progression from RAAS Inhibition and Onward
SS Blumenthal
Postgraduate Medicine 2011
Regenerative Nephrology
S Gavrilov, DW Landry
Regenerative Nephrology 2011
SOX9 Protein Induces a Chondrogenic Phenotype of Mesangial Cells and Contributes to Advanced Diabetic Nephropathy
S Kishi, H Abe, H Akiyama, T Tominaga, T Murakami, A Mima, K Nagai, F Kishi, M Matsuura, T Matsubara, N Iehara, O Ueda, N Fukushima, K Jishage, T Doi
The Journal of biological chemistry 2011
The proximal tubule in the pathophysiology of the diabetic kidney
V Vallon
American Journal of Physiology - Regulatory, Integrative and Comparative Physiology 2011
Diabetes & C-Peptide
AA Sima
2011
Pyridorin in Type 2 Diabetic Nephropathy
EJ Lewis, T Greene, S Spitalewiz, S Blumenthal, T Berl, LG Hunsicker, MA Pohl, RD Rohde, I Raz, Y Yerushalmy, Y Yagil, T Herskovits, RC Atkins, AT Reutens, DK Packham, JB Lewis
Journal of the American Society of Nephrology : JASN 2011
1. Diabetic Nephropathy
T Moriya
Nihon Naika Gakkai Zasshi 2011
The Protective Role of Smad7 in Diabetic Kidney Disease: Mechanism and Therapeutic Potential
HY Chen, XR Huang, W Wang, JH Li, RL Heuchel, AC Chung, HY Lan
Diabetes 2010
The proximal tubule in the pathophysiology of the diabetic kidney
V Vallon
American Journal of Physiology - Regulatory, Integrative and Comparative Physiology 2010
Metabolic memory: a vascular perspective
TW Jax
Cardiovascular Diabetology 2010
Targeted Disruption of Guanylyl Cyclase-A/Natriuretic Peptide Receptor-A Gene Provokes Renal Fibrosis and Remodeling in Null Mutant Mice: Role of Proinflammatory Cytokines
S Das, E Au, ST Krazit, KN Pandey
Endocrinology 2010
Abnormalities in signaling pathways in diabetic nephropathy
FC Brosius, CC Khoury, CL Buller, S Chen
Expert Review of Endocrinology & Metabolism 2010
Regression of microalbuminuria in type 1 diabetes is associated with lower levels of urinary tubular injury biomarkers, kidney injury molecule-1, and N-acetyl-β-D-glucosaminidase
VS Vaidya, MA Niewczas, LH Ficociello, AC Johnson, FB Collings, JH Warram, AS Krolewski, JV Bonventre
Kidney International 2010
The relationship of retinal vessel diameter to changes in diabetic nephropathy structural variables in patients with type 1 diabetes
R Klein, MD Knudtson, BE Klein, B Zinman, R Gardiner, S Suissa, AR Sinaiko, SM Donnelly, P Goodyer, T Strand, M Mauer
Diabetologia 2010
PRAS40 acts as a nodal regulator of high glucose-induced TORC1 activation in glomerular mesangial cell hypertrophy
N Dey, N Ghosh-Choudhury, F Das, X Li, B Venkatesan, JL Barnes, BS Kasinath, GG Choudhury
Journal of Cellular Physiology 2010
Impact of pancreas transplantation on type 1 diabetes-related complications
C Gremizzi, A Vergani, V Paloschi, A Secchi
Current Opinion in Organ Transplantation 2010
Involvement of osteopontin upregulation on mesangial cells growth and collagen synthesis induced by intermittent high glucose
J Sun, Y Xu, H Deng, S Sun, Z Dai, Y Sun
Journal of Cellular Biochemistry 2010
Diabetic nephropathy: Diabetic nephropathy—challenges in pathologic classification
P Fioretto, M Mauer
Nature Reviews Nephrology 2010
Soluble CD40 ligand is elevated in Type 1 diabetic nephropathy but not predictive of mortality, cardiovascular events or kidney function
M Lajer, I Tarnow, AD Michelson, A Jorsal, AL Frelinger, HH Parving, P Rossing, L Tarnow
Platelets 2010
Extract of the aerial parts of Aster koraiensis reduced development of diabetic nephropathy via anti-apoptosis of podocytes in streptozotocin-induced diabetic rats
E Sohn, J Kim, CS Kim, YS Kim, DS Jang, JS Kim
Biochemical and Biophysical Research Communications 2010
Fluctuations in glycosylated hemoglobin (HbA1C) as a predictor for the development of diabetic nephropathy in type 1 diabetic patients
JE Fares, M Kanaan, M Chaaya, ST Azar
International Journal of Diabetes Mellitus 2010
Miller's Anesthesia
RN Sladen
Miller's Anesthesia 2010
Renin-Angiotensin System Blockade for Diabetic Nephropathy Prevention
S Naviglio, F Pirozzi
The American Journal of Cardiology 2010
Neovascularization in diabetes
JP Glotzbach, VW Wong, GC Gurtner
Expert Review of Endocrinology & Metabolism 2010
Different expression of Fibrinopeptide A and related fragments in serum of type 1 diabetic patients with nephropathy
E Gianazza, V Mainini, G Castoldi, C Chinello, G Zerbini, C Bianchi, C Galbusera, A Stella, G Mauri, I Zoppis, F Magni, MG Kienle
Journal of Proteomics 2010
Influence of genetic background on albuminuria and kidney injury in Ins2+/C96Y (Akita) mice
SB Gurley, CL Mach, J Stegbauer, J Yang, KP Snow, A Hu, TW Meyer, TM Coffman
American journal of physiology. Renal physiology 2010
Human glomerular endothelium: interplay among glucose, free fatty acids, angiotensin II, and oxidative stress
EA Jaimes, P Hua, RX Tian, L Raij
American journal of physiology. Renal physiology 2010
Histone Deacetylase: A Potential Therapeutic Target for Fibrotic Disorders
M Pang, S Zhuang
The Journal of pharmacology and experimental therapeutics 2010
Glucose Variability; Does It Matter?
SE Siegelaar, F Holleman, JB Hoekstra, JH DeVries
Endocrine reviews 2010
Diabetic nephropathy—challenges in pathologic classification
P Fioretto, M Mauer
Nature Reviews Nephrology 2010
Pulmonary surfactant: an immunological perspective
ZC Chroneos, Z Sever-Chroneos, VL Shepherd
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2009
Human glomerular endothelium: interplay among glucose, free fatty acids, angiotensin II, and oxidative stress
EA Jaimes, P Hua, RX Tian, L Raij
American journal of physiology. Renal physiology 2009
Therapies for hyperglycaemia-induced diabetic complications: from animal models to clinical trials
NA Calcutt, ME Cooper, TS Kern, AM Schmidt
Nature Reviews Drug Discovery 2009
Endothelial-mesenchymal transition as a novel mechanism for generating myofibroblasts during diabetic nephropathy
A Kizu, D Medici, R Kalluri
The American Journal of Pathology 2009
The natural progression of kidney injury in young type 1 diabetic patients
JM Steinke
Current Diabetes Reports 2009
Protective effects of thymoquinone on streptozotocin-induced diabetic nephropathy
M Kanter
Journal Of Molecular Histology 2009
Urocortin 1 improves renal function in rats with streptozotocin-induced diabetes by inhibiting overproduction of TGF-β1 and VEGF
X Li, J Hu, Q Zhang, X Sun, S Li
British Journal of Pharmacology 2009
Diabetic Nephropathy in Childhood and Adolescence (II) ; Pathology and Pathophysiology
TS Ha
Journal of the Korean Society of Pediatric Nephrology 2009
Protective Effect of Tanshinone IIA on the Early Stage of Experimental Diabetic Nephropathy
SK Kim, KH Jung, BC Lee
Biological & Pharmaceutical Bulletin 2009
Ginkgo bilobaextract prevents glucose-induced accumulation of ECM in rat mesangial cells
L Ji, X Yin, Z Wu, J Wang, Q Lu, Y Gao
Phytotherapy Research 2009
Mangiferin prevents diabetic nephropathy progression in streptozotocin-induced diabetic rats
X Li, X Cui, X Sun, X Li, Q Zhu, W Li
Phytotherapy Research 2009
Influence of genetic background on albuminuria and kidney injury in Ins2(+/C96Y) (Akita) mice
SB Gurley, CL Mach, J Stegbauer, J Yang, KP Snow, A Hu, TW Meyer, TM Coffman
American journal of physiology. Renal physiology 2009
Renal and retinal effects of enalapril and losartan in type 1 diabetes
M Mauer, B Zinman, R Gardiner, S Suissa, A Sinaiko, T Strand, K Drummond, S Donnelly, P Goodyer, MC Gubler, R Klein
The New England journal of medicine 2009
Progression of diabetic nephropathy in type 1 diabetic patients
B Najafian, M Mauer
Diabetes Research and Clinical Practice 2009
Diabetic Nephropathy in the Elderly
AJ Joseph, EA Friedman
Clinics in Geriatric Medicine 2009
Are low erythropoietin and 1,25-dihydroxyvitamin D levels indicative of tubulo-interstitial dysfunction in diabetes without persistent microalbuminuria?
DK Singh, P Winocour, B Summerhayes, A Viljoen, G Sivakumar, K Farrington
Diabetes Research and Clinical Practice 2009
The kidney in type 2 diabetes: focus on renal structure
MD Vestra, M Arboit, M Bruseghin, P Fioretto
Endocrinología y Nutrición 2009
Renal tubulointerstitial expansion is associated with endothelial dysfunction and inflammation in type 1 diabetes
HJ Bangstad, I Seljeflot, TJ Berg, KF Hanssen
Scandinavian Journal of Clinical & Laboratory Investigation 2009
6. Diabetic Nephropathy
Gábor L. Kovács
EJIFCC 2009
Histone deacetylase-2 is a key regulator of diabetes- and transforming growth factor-β1-induced renal injury
H Noh, EY Oh, JY Seo, MR Yu, YO Kim, H Ha, HB Lee
American journal of physiology. Renal physiology 2009
Decorin deficiency in diabetic mice: aggravation of nephropathy due to overexpression of profibrotic factors, enhanced apoptosis and mononuclear cell infiltration
R Merline, S Lazaroski, A Babelova, W Tsalastra-Greul, J Pfeilschifter, K D Schluter, A Gunther, R V Iozzo, R M Schaefer, L Schaefer
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 2009
RAS inhibition: probably not a one-size-fits-all approach
DP Barlovic, ME Cooper
Nature Reviews Nephrology 2009
New Insights into the Mechanisms of Fibrosis and Sclerosis in Diabetic Nephropathy
FC Brosius
Reviews in Endocrine and Metabolic Disorders 2008
Rhein reverses the diabetic phenotype of mesangial cells over-expressing the glucose transporter (GLUT1) by inhibiting the hexosamine pathway
JM Zheng, JM Zhu, LS Li, ZH Liu
British Journal of Pharmacology 2008
Association of Urinary Inflammatory Markers and Renal Decline in Microalbuminuric Type 1 Diabetics
PP Wolkow, MA Niewczas, B Perkins, LH Ficociello, B Lipinski, JH Warram, AS Krolewski
Journal of the American Society of Nephrology : JASN 2008
From Fibrosis to Sclerosis: Mechanisms of Glomerulosclerosis in Diabetic Nephropathy
Y Qian, E Feldman, S Pennathur, M Kretzler, FC Brosius
Diabetes 2008
Albuminuria and Dementia in the Elderly: A Community Study
JI Barzilay, AL Fitzpatrick, J Luchsinger, S Yasar, C Bernick, NS Jenny, LH Kuller
American Journal of Kidney Diseases 2008
The kidney in diabetes: dynamic pathways of injury and repair. The Camillo Golgi Lecture 2007
P Fioretto, ML Caramori, M Mauer
Diabetologia 2008
VASOPRESSIN STIMULATES THE PRODUCTION OF EXTRACELLULAR MATRIX BY CULTURED RAT MESANGIAL CELLS
A Tahara, J Tsukada, Y Tomura, T Suzuki, T Yatsu, M Shibasaki
Clinical and Experimental Pharmacology and Physiology 2008
Proinsulin C-peptide abrogates type-1 diabetes-induced increase of renal endothelial nitric oxide synthase in rats
A Kamikawa, T Ishii, K Shimada, K Makondo, O Inanami, N Sakane, T Yoshida, M Saito, K Kimura
Diabetes/Metabolism Research and Reviews 2008
Proteomics in diabetic nephropathy
HJ Kim, HS Yoo, CW Kim
PROTEOMICS – CLINICAL APPLICATIONS 2008
Renal structure as an indicator for development of albuminuria in normo- and microalbuminuric type 2 diabetic patients
T Moriya, K Tanaka, T Hosaka, Y Hirasawa, Y Fujita
Diabetes Research and Clinical Practice 2008
APPLICATION OF AN ADENOVIRAL VECTOR ENCODING SOLUBLE TRANSFORMING GROWTH FACTOR-β TYPE II RECEPTOR TO THE TREATMENT OF DIABETIC NEPHROPATHY IN MICE
T Kondo, G Takemura, K Kosai, T Ohno, T Takahashi, M Esaki, K Goto, R Maruyama, I Murata, S Minatoguchi, T Fujiwara, H Fujiwara
Clinical and Experimental Pharmacology and Physiology 2008
Early changes in renal hemodynamics in children with diabetes: Doppler sonographic findings
P Pelliccia, A Savino, C Cecamore, A Primavera, C Schiavone, F Chiarelli
Journal of Clinical Ultrasound 2008
The pathogenesis of diabetic nephropathy
S Dronavalli, I Duka, GL Bakris
Nature Clinical Practice Endocrinology & Metabolism 2008
Complications of type 1 diabetes: new molecular findings
A Stirban, P Rösen, D Tschoepe
Mount Sinai Journal of Medicine: A Journal of Translational and Personalized Medicine 2008
Detailed glomerular ultrastructure in Japanese type 2 diabetic patients by the quick-freezing and deep-etching method
T Moriya, S Ohno, Y Hirasawa, K Tanaka, Y Fujita
Diabetes Research and Clinical Practice 2008
Protective Effects of Lithospermic Acid B on Diabetic Nephropathy in OLETF Rats Comparing with Amlodipine and Losartan
ES Kang, BS Kim, CH Kim, GH Seo, SJ Han, SW Chun, KY Hur, CW Ahn, H Ha, M Jung, BS Cha, HC Lee
Korean Diabetes Journal 2008
Mechanisms of Disease: the hypoxic tubular hypothesis of diabetic nephropathy
DK Singh, P Winocour, K Farrington
Nature Clinical Practice Nephrology 2008
Effect of Angiotensin-Converting Enzyme Inhibition and Angiotensin II Type 1 Receptor Blockade on Streptozotocin-Induced Diabetic Nephropathy
S Sen, M Kanter, S Ustundag, C Aktas, H Dogutan, O Yalcin
Renal Failure 2008
Soybeans ameliolate diabetic nephropathy in rats
YE Choi, SK Ahn, WT Lee, JE Lee, SH Park, BB Yoon, KA Park
Evidence-based complementary and alternative medicine : eCAM 2008
Sepsis-induced inflammation is exacerbated in an animal model of type 2 diabetes
A Jacob, ML Steinberg, J Yang, W Dong, Y Ji, P Wang
International journal of clinical and experimental medicine 2008
Intervention with cilostazol attenuates renal inflammation in streptozotocin-induced diabetic rats
F Wang, M Li, L Cheng, T Zhang, J Hu, M Cao, J Zhao, RC Guo, L Gao, X Zhang
Life Sciences 2008
The current clinical problems for early phase of diabetic nephropathy and approach for pathogenesis of diabetic nephropathy
T Doi, A Mima, T Matsubara, T Tominaga, H Arai, H Abe
Diabetes Research and Clinical Practice 2008
Effect of vasopressin on type IV collagen production in human mesangial cells
A Tahara, J Tsukada, Y Tomura, T Suzuki, T Yatsu, M Shibasaki
Regulatory Peptides 2008
Spironolactone exhibits direct renoprotective effects and inhibits renal renin–angiotensin–aldosterone system in diabetic rats
M Taira, H Toba, M Murakami, I Iga, R Serizawa, S Murata, M Kobara, T Nakata
European Journal of Pharmacology 2008
Having One Kidney Does Not Accelerate the Rate of Development of Diabetic Nephropathy Lesions in Type 1 Diabetic Patients
S Chang, ML Caramori, R Moriya, M Mauer
Diabetes 2008
Local renal aldosterone production induces inflammation and matrix formation in kidneys of diabetic rats: Aldosterone and renal inflammation
HM Siragy, C Xue
Experimental Physiology 2008
Is the Presence of Retinopathy of Practical Value in Defining Cases of Diabetic Nephropathy in Genetic Association Studies?: The Experience With the ACE Insertion/Deletion Polymorphism in 53 Studies Comprising 17,791 Subjects
DP Ng, BC Tai, XL Lim
Diabetes 2008
Enhanced Expression of Janus Kinase-Signal Transducer and Activator of Transcription Pathway Members in Human Diabetic Nephropathy
CC Berthier, H Zhang, M Schin, A Henger, RG Nelson, B Yee, A Boucherot, MA Neusser, CD Cohen, C Carter-Su, LS Argetsinger, MP Rastaldi, FC Brosius, M Kretzler
Diabetes 2008
Rosiglitazone reduces renal and plasma markers of oxidative injury and reverses urinary metabolite abnormalities in the amelioration of diabetic nephropathy
H Zhang, J Saha, J Byun, ML Schin, M Lorenz, RT Kennedy, M Kretzler, EL Feldman, S Pennathur, FC Brosius
American journal of physiology. Renal physiology 2008
Papel do sistema endotelina na nefropatia diabética
CM Zanatta, LH Canani, SP Silveiro, L Burttet, G Nabinger, JL Gross
Arquivos brasileiros de endocrinologia e metabologia 2008
Glucose Transporter 12 and Mammalian Target of Rapamycin Complex 1 Signaling: A New Target for Diabetes-Induced Renal Injury?
H Schmid, M Bertoluci, TM Coimbra
Endocrinology 2008
Lowering of Proteinuria in Response to Antihypertensive Therapy Predicts Improved Renal Function in Late but Not in Early Diabetic Nephropathy: A Pooled Analysis
G Jerums, S Panagiotopoulos, E Premaratne, DA Power, RJ MacIsaac
American Journal of Nephrology 2008
Raptor-rictor axis in TGFβ-induced protein synthesis
F Das, N Ghosh-Choudhury, L Mahimainathan, B Venkatesan, D Feliers, DJ Riley, BS Kasinath, GG Choudhury
Cellular Signalling 2008
Diabetes and chronic kidney disease: lessons from the Pima Indians
KV Lemley
Pediatric Nephrology 2008
Diabetic nephropathy in children and adolescents
R Bogdanović
Pediatric Nephrology 2008
Histone deacetylase inhibitors: A novel class of therapeutic agents in diabetic nephropathy
HB Lee, H Noh, JY Seo, MR Yu, H Ha
Kidney International 2007
Heparanase induces a differential loss of heparan sulphate domains in overt diabetic nephropathy
TJ Wijnhoven, MJ van den Hoven, H Ding, TH van Kuppevelt, J van der Vlag, JH Berden, RA Prinz, EJ Lewis, M Schwartz, X Xu
Diabetologia 2007
Loss of angiotensin-converting enzyme-2 (Ace2) accelerates diabetic kidney injury
DW Wong, GY Oudit, H Reich, Z Kassiri, J Zhou, QC Liu, PH Backx, JM Penninger, AM Herzenberg, JW Scholey
The American Journal of Pathology 2007
Farnesoid X Receptor Modulates Renal Lipid Metabolism, Fibrosis, and Diabetic Nephropathy
T Jiang, XX Wang, P Scherzer, P Wilson, J Tallman, H Takahashi, J Li, M Iwahashi, E Sutherland, L Arend, M Levi
Diabetes 2007
Podocyte Detachment and Reduced Glomerular Capillary Endothelial Fenestration in Human Type 1 Diabetic Nephropathy
M Toyoda, B Najafian, Y Kim, ML Caramori, M Mauer
Diabetes 2007
Decorin Deficiency Enhances Progressive Nephropathy in Diabetic Mice
KJ Williams, G Qiu, HK Usui, SR Dunn, P McCue, E Bottinger, RV Iozzo, K Sharma
The American Journal of Pathology 2007
Are glomerular volume differences between type 1 and type 2 diabetic patients pathologically significant?
KE White, SM Marshall, RW Bilous
Diabetologia 2007
Monocyte chemoattractant protein-1 has prosclerotic effects both in a mouse model of experimental diabetes and in vitro in human mesangial cells
S Giunti, GH Tesch, S Pinach, DJ Burt, ME Cooper, P Cavallo-Perin, G Camussi, G Gruden
Diabetologia 2007
Alteration of glomerulogenesis- and podocyte structure-related gene expression in early diabetic nephropathy
H Makino, S Suga
Expert Review of Endocrinology & Metabolism 2007
Advanced glycation end products decrease mesangial cell MMP-7: A role in matrix accumulation in diabetic nephropathy?
SV McLennan, DJ Kelly, M Schache, M Waltham, V Dy, RG Langham, DK Yue, RE Gilbert
Kidney International 2007
Navigating pathways affecting type 1 diabetic kidney disease
L Pasquali, M Trucco, S Ringquist
Pediatric Diabetes 2007
Nodular glomerular lesion: A later stage of diabetic nephropathy?
D Hong, T Zheng, S Jia-qing, W Jian, L Zhi-hong, L Lei-shi
Diabetes Research and Clinical Practice 2007
Glomerular barrier dysfunction in glomerulosclerosis- resistant Milan rats with experimental diabetes: the role of renal haemodynamics
G Pugliese, C Ricci, C Iacobini, S Menini, P Fioretto, M Ferrandi, LA Giardino, S Armelloni, D Mattinzoli, MP Rastaldi, F Pugliese
The Journal of Pathology 2007
Diabetic nephropathy in children and adolescents
R Bogdanović
Pediatric Nephrology 2007
Y-box protein-1 controls transforming growth factor-β1 translation in proximal tubular cells
DJ Fraser, AO Phillips, X Zhang, CR van Roeyen, P Muehlenberg, A En-Nia, PR Mertens
Kidney International 2007
Overexpression of connective tissue growth factor in podocytes worsens diabetic nephropathy in mice
H Yokoi, M Mukoyama, K Mori, M Kasahara, T Suganami, K Sawai, T Yoshioka, Y Saito, Y Ogawa, T Kuwabara, A Sugawara, K Nakao
Kidney International 2007
Histopathology of diabetic nephropathy
P Fioretto, M Mauer
Seminars in Nephrology 2007
Novel roles of the IGF-IGFBP axis in etiopathophysiology of diabetic nephropathy
TL Vasylyeva, RJ Ferry
Diabetes Research and Clinical Practice 2007
Protective effects of keishibukuryogan on the kidney of spontaneously diabetic WBN/Kob rats
T Nakagawa, H Goto, H Hikiami, T Yokozawa, N Shibahara, Y Shimada
Journal of Ethnopharmacology 2007
Type 1 Diabetes in Adults: Principles and Practice
J Cropsey, M Fineman
Type 1 Diabetes in Adults: Principles and Practice 2007
Diabetic nephropathy: An update on renal structure
P Fioretto, M Bruseghin, I Barzon, M Arboit, MD Vestra
International Congress Series 2007
Renal Fibrosis and Glomerulosclerosis in a New Mouse Model of Diabetic Nephropathy and Its Regression by Bone Morphogenic Protein-7 and Advanced Glycation End Product Inhibitors
H Sugimoto, G Grahovac, M Zeisberg, R Kalluri
Diabetes 2007
Effects on protein kinase C-β inhibition on glomerular vascular endothelial growth factor expression and endothelial cells in advanced experimental diabetic nephropathy
DJ Kelly, D Buck, AJ Cox, Y Zhang, RE Gilbert
American journal of physiology. Renal physiology 2007
Intrarenal Resistive Index in Patients with Type 2 Diabetes Mellitus with and without Microalbuminuria
M Sperandeo, A Varriale, G D'Amico, G Sperandeo, ML Piattelli, A Cata, A Greco, F Prigigallo, MA Annese, L Cedrone, G Vendemiale
EUR J INFLAMM 2007
Overexpression of upstream stimulatory factor 2 accelerates diabetic kidney injury
S Liu, L Shi, S Wang
American journal of physiology. Renal physiology 2007
Recent Advancement of Understanding Pathogenesis of Type 1 Diabetes and Potential Relevance to Diabetic Nephropathy
K Ichinose, E Kawasaki, K Eguchi
American Journal of Nephrology 2007
Expression of Smad1 is directly associated with mesangial matrix expansion in rat diabetic nephropathy
T Matsubara, H Abe, H Arai, K Nagai, A Mima, H Kanamori, E Sumi, T Takahashi, M Matsuura, N Iehara, A Fukatsu, T Kita, T Doi
Laboratory Investigation 2006
Regulation of Renal Fatty Acid and Cholesterol Metabolism, Inflammation, and Fibrosis in Akita and OVE26 Mice With Type 1 Diabetes
G Proctor, T Jiang, M Iwahashi, Z Wang, J Li, M Levi
Diabetes 2006
Mesangial Cell Hypertrophy by High Glucose Is Mediated by Downregulation of the Tumor Suppressor PTEN
L Mahimainathan, F Das, B Venkatesan, GG Choudhury
Diabetes 2006
Blockade of the renin–angiotensin–aldosterone system: a key therapeutic strategy to reduce renal and cardiovascular events in patients with diabetes
M Burnier, A Zanchi
Journal of Hypertension 2006
Effect of polysaccharides fromGanoderma lucidumon streptozotocin-induced diabetic nephropathy in mice
CY He, WD Li, SX Guo, SQ Lin, ZB Lin
Journal of Asian Natural Products Research 2006
Diabetes and Nephropathy
MH Kroll
Point of Care: The Journal of Near-Patient Testing & Technology 2006
Simvastatin maintains steady patterns of GFR and improves AER and expression of slit diaphragm proteins in type II diabetes
G Tonolo, M Velussi, E Brocco, C Abaterusso, A Carraro, G Morgia, A Satta, R Faedda, A Abhyankar, H Luthman, R Nosadini
Kidney International 2006
Remodeling of renal interstitial and tubular lesions in pancreas transplant recipients
P Fioretto, DE Sutherland, B Najafian, M Mauer
Kidney International 2006
The course of diabetic glomerulopathy in patients with type I diabetes: A 6-year follow-up with serial biopsies
NE Perrin, TB Torbjörnsdotter, GA Jaremko, UB Berg
Kidney International 2006
Time to abandon microalbuminuria?
P Ruggenenti, G Remuzzi
Kidney International 2006
Growth factors in diabetic complications
SE Thomson, SV McLennan, SM Twigg
Expert Review of Clinical Immunology 2006
Urinary Excretion of Guanidinoacetic Acid in Rats with Diabetic Nephropathy
I Kiyatake, T Nakamura, H Koide
Renal Failure 2006
Enfermedades vasculares
AB Fogo, M Kashgarian
Atlas diagnóstico de patología renal 2006
Pancreatic Transplantation: 1966–2005
D Sutherland, R Gruessner, D Dunn, A Matas, A Humar, R Kandaswamy, A Gruessner, J Najarian, S Mauer, W Kennedy, F Goetz, R Robertson
Pancreatic Transplantation: 1966–2005 2006
Transforming Growth Factor-  in Human Diabetic Nephropathy: Effects of ACE inhibition
RG Langham, DJ Kelly, RM Gow, Y Zhang, DJ Cordonnier, N Pinel, P Zaoui, RE Gilbert
Diabetes care 2006
Reduction in podocyte density as a pathologic feature in early diabetic nephropathy in rodents: Prevention by lipoic acid treatment
B Siu, J Saha, WE Smoyer, KA Sullivan, FC Brosius
BMC Nephrology 2006
The Diabetic Kidney
P Cortes, CE Mogensen
2006
Hepatocyte growth factor gene therapy slows down the progression of diabetic nephropathy in db/db mice
T Kagawa, G Takemura, K Kosai, I Murata, T Ohno, T Takahashi, M Esaki, R Maruyama, T Fujiwara, H Ohashi, H Fujiwara
Nephron Physiology 2005
Plasminogen activator inhibitor-1 deficiency retards diabetic nephropathy
SB Nicholas, E Aguiniga, Y Ren, J Kim, J Wong, N Govindarajan, M Noda, W Wang, Y Kawano, A Collins, WA Hsueh
Kidney International 2005
The salt paradox and its possible implications in managing hypertensive diabetic patients
V Vallon, R Blantz, S Thomson
Current Hypertension Reports 2005
Widening of foot processes in normoalbuminuric adolescents with type 1 diabetes
TB Torbjörnsdotter, NE Perrin, GA Jaremko, UB Berg
Pediatric Nephrology 2005
Nutrition and Diabetes
R Hoeldtke
Nutrition and Diabetes 2005
Glucose transporters in diabetic nephropathy
FC Brosius, CW Heilig
Pediatric Nephrology 2005
Renoprotective effect of benazepril on diabetic nephropathy mediated by P42/44MAPK
LV Yongman, D Junwu, N Xiaochun, L Xiaocheng
Journal of Huazhong University of Science and Technology [Medical Sciences] 2005
Interaction of haemodynamic and metabolic pathways in the genesis of diabetic nephropathy
CA Leon, L Raij
Journal of Hypertension 2005
Diabetic nephropathy: Big and bad
Z Qi, MD Breyer
Kidney International 2005
Long-term treatment with Hachimi-jio-gan attenuates kidney damage in spontaneously diabetic WBN/Kob rats
T Nakagawa, T Yokozawa, N Yamabe, H Goto, N Shibahara, DY Rhyn, Y Shimada
Journal of Pharmacy and Pharmacology 2005
Water extract of the root of Lindera strychnifolia slows down the progression of diabetic nephropathy in db/db mice
T Ohno, G Takemura, I Murata, T Kagawa, S Akao, S Minatoguchi, T Fujiwara, H Fujiwara
Life Sciences 2005
Diabetic nephropathy: Of mice and men
MD Breyer, E Böttinger, FC Brosius, TM Coffman, A Fogo, RC Harris, CW Heilig, K Sharma
Advances in Chronic Kidney Disease 2005
Identification of urinary protein pattern in Type 1 diabetic adolescents with early diabetic nephropathy by a novel combined proteome analysis
M Meier, T Kaiser, A Herrmann, S Knueppel, M Hillmann, P Koester, T Danne, H Haller, D Fliser, H Mischak
Journal of Diabetes and its Complications 2005
A novel polymorphism in the 5′ flanking region of the glucose transporter (GLUT1) gene is strongly associated with diabetic nephropathy in patients with Type 1 diabetes mellitus
A Hodgkinson, T Page, B Millward, A Demaine
Journal of Diabetes and its Complications 2005
C-peptide prevents glomerular hypertrophy and mesangial matrix expansion in diabetic rats
B Samnegard, SH Jacobson, G Jaremko, BL Johansson, K Ekberg, B Isaksson, L Eriksson, J Wahren, M Sjoquist
Nephrology Dialysis Transplantation 2005
Processing Advanced Glycation End Product-Modified Albumin by the Renal Proximal Tubule and the Early Pathogenesis of Diabetic Nephropathy
AM Ozdemir, U Hopfer, P Erhard, VM Monnier, MF Weiss
Annals of the New York Academy of Sciences 2005
Alterations of glomerular and extracellular levels of glutathione peroxidase in patients and experimental rats with diabetic nephropathy
YI Chiu, MC Kuo, HT Kuo, JM Chang, JY Guh, YH Lai, HC Chen
Journal of Laboratory and Clinical Medicine 2005
Increased glomerular and extracellular malondialdehyde levels in patients and rats with diabetic nephropathy
JM Chang, MC Kuo, HT Kuo, YI Chiu, HC Chen
Journal of Laboratory and Clinical Medicine 2005
Increased Renal Arterial Resistance Predicts the Course of Renal Function in Type 2 Diabetes With Microalbuminuria
R Nosadini, M Velussi, E Brocco, C Abaterusso, A Carraro, F Piarulli, G Morgia, A Satta, R Faedda, A Abhyankar, H Luthman, G Tonolo
Diabetes 2005
Susceptibility to diabetic nephropathy is related to dicarbonyl and oxidative stress
Paul J Beisswenger, Keith S Drummond, Robert G Nelson, Scott K Howell, Benjamin S Szwergold, Michael Mauer
Diabetes 2005
Protective effect of polyphenol-containing azuki bean (Vigna angularis) seed coats on the renal cortex in streptozotocin-induced diabetic rats
S Sato, J Yamate, Y Hori, A Hatai, M Nozawa, M Sagai
The Journal of Nutritional Biochemistry 2005
RAGE‐ and TGF‐ β receptor‐mediated signals converge on STAT5 and p21 waf to control cell‐cycle progression of mesangial cells: a possible role in the development and progression of diabetic nephropathy
MF Brizzi, P Dentelli, A Rosso, C Calvi, R Gambino, M Cassader, G Salvidio, G Deferrari, G Camussi, L Pegoraro, G Pagano, P Cavallo-Perin
The FASEB Journal 2004
Transforming growth factor-beta: A clinical target for the treatment of diabetic nephropathy
TA McGowan, Y Zhu, K Sharma
Current Diabetes Reports 2004
Relationship between levels of urinary type IV collagen and renal injuries in patients with IgA nephropathy
H Io, C Hamada, M Fukui, S Horikoshi, Y Tomino
Journal of Clinical Laboratory Analysis 2004
Cellular basis of diabetic nephropathy: III. In vitro GLUT1 mRNA expression and risk of diabetic nephropathy in Type 1 diabetic patients
C Huang, Y Kim, ML Caramori, AJ Fish, SS Rich, ME Miller, GB Russell, M Mauer
Diabetologia 2004
TNP-470, an angiogenesis inhibitor, suppresses the progression of peritoneal fibrosis in mouse experimental model
Y Yoshio, M Miyazaki, K Abe, T Nishino, A Furusu, Y Mizuta, T Harada, Y Ozono, T Koji, S Kohno
Kidney International 2004
Diabetic nephropathy: Linking histology, cell biology, and genetics
S Adler
Kidney International 2004
Elevated ε-(γ-Glutamyl)lysine in Human Diabetic Nephropathy Results from Increased Expression and Cellular Release of Tissue Transglutaminase
AM Nahas, H Abo-Zenah, NJ Skill, S Bex, G Wild, M Griffin, TS Johnson
Nephron Clinical Practice 2004
New insights into the pathophysiology of diabetic nephropathy: from haemodynamics to molecular pathology
G Wolf
European Journal of Clinical Investigation 2004
Spironolactone prevents early renal injury in streptozotocin-induced diabetic rats
G Fujisawa, K Okada, S Muto, N Fujita, N Itabashi, E Kusano, S Ishibashi
Kidney International 2004
Phytolacca americana inhibits the high glucose-induced mesangial proliferation via suppressing extracellular matrix accumulation and TGF-β production
SI Jeong, KJ Kim, YK Choo, KS Keum, BK Choi, KY Jung
Phytomedicine 2004
Structural alterations to the podocyte are related to proteinuria in type 2 diabetic patients
KE White, RW Bilous
Nephrology Dialysis Transplantation 2004
Upstream Stimulatory Factor (USF) Proteins Induce Human TGF -β 1 Gene Activation via the Glucose-response Element–1013/–1002 in Mesangial Cells: UP-REGULATION OF USF ACTIVITY BY THE HEXOSAMINE BIOSYNTHETIC PATHWAY
C Weigert, K Brodbeck, M Sawadogo, HU Häring, ED Schleicher
The Journal of biological chemistry 2004
ERK and p38 mediate high-glucose-induced hypertrophy and TGF-β expression in renal tubular cells
H Fujita, S Omori, K Ishikura, M Hida, M Awazu
American journal of physiology. Renal physiology 2004
Transplantation of the Pancreas
RW Gruessner, DE Sutherland
2004
Follow-up of kidney biopsies in normoalbuminuric patients with type 1 diabetes
NE Perrin, TB Torbjrnsdotter, GA Jaremko, UB Berg
Pediatric Nephrology 2004
Genomic Strategies for Diabetic Nephropathy
K Susztak, K Sharma, M Schiffer, P McCue, E Ciccone, EP Böttinger
Journal of the American Society of Nephrology : JASN 2003
The role of renal proximal tubular cells in diabetic nephropathy
AO Phillips
Current Diabetes Reports 2003
Long-term treatment with ramipril attenuates renal osteopontin expression in diabetic rats
C Li, CW Yang, CW Park, HJ Ahn, WY Kim, KH Yoon, SH Suh, SW Lim, JH Cha, YS Kim, J Kim, YS Chang, BK Bang
Kidney International 2003
Hypertension Accelerates Diabetic Nephropathy in Wistar Fatty Rats, a Model of Type 2 Diabetes Mellitus, via Mitogen-Activated Protein Kinase Cascades and Transforming Growth Factor-.BETA.1
G IMAI, T SATOH, T KUMAI, M MURAO, H TSUCHIDA, Y SHIMA, G OGIMOTO, T FUJINO, S KOBAYASHI, K KIMURA
Hypertension Research 2003
Remission and Regression of Diabetic Nephropathy
H MAKINO, Y NAKAMURA, J WADA
Hypertension Research 2003
Glucose-induced fibronectin and collagen type III expression in renal fibroblasts can occur independent of TGF-beta1
S Lam, NA Verhagen, F Strutz, JW van der Pijl, MR Daha, CV Kooten
Kidney International 2003
Glomerular expression of connective tissue growth factor mRNA in various renal diseases
D SUZUKI, M TOYODA, T UMEZONO, G UEHARA, SY ZHANG, T SAKAI, M NISHINA, T SUGA, M ENDOH, M YAGAME, H SAKAI
Nephrology 2003
Methylglyoxal induces apoptosis through activation of p38 mitogen-activated protein kinase in rat mesangial cells
BF Liu, S Miyata, Y Hirota, S Higo, H Miyazaki, M Fukunaga, Y Hamada, S Ueyama, O Muramoto, A Uriuhara, M Kasuga
Kidney International 2003
Enlarged nephrons and severe nondiabetic nephropathy in hepatocyte nuclear factor-1beta (HNF-1beta) mutation carriers
JV Sagen, L Bostad, PR Njolstad, O Sovik
Kidney International 2003
Reversibility of established diabetic glomerulopathy by anti-TGF-β antibodies in db/db mice
S Chen, MC la Cruz, B Jim, SW Hong, M Isono, FN Ziyadeh
Biochemical and Biophysical Research Communications 2003
Diabetic nephropathy and transforming growth factor-β: transforming our view of glomerulosclerosis and fibrosis build-up
S Chen, B Jim, FN Ziyadeh
Seminars in Nephrology 2003
Intervention strategies to prevent pathogenetic effects of glycated albumin
MP Cohen
Archives of Biochemistry and Biophysics 2003
Diabetic kidney disease in the db / db mouse
K Sharma, P McCue, SR Dunn
American journal of physiology. Renal physiology 2003
Down-regulation of nitric oxide synthase in the diabetic rabbit kidney: potential relevance to the early pathogenesis of diabetic nephropathy
FH Mumtaz, MR Dashwood, MA Khan, CS Thompson, DP Mikhailidis, RJ Morgan
Current Medical Research and Opinion 2003
Pediatric Diabetes
RK Menon, MA Sperling
Pediatric Diabetes 2003
Protective effects of chronic melatonin treatment against renal injury in streptozotocin-induced diabetic rats: Melatonin and renal injury
M Cam, Ö Yavuz, A Guven, F Ercan, N Bukan, N Üstündag
Journal of Pineal Research 2003
The Lack of Cyclin Kinase Inhibitor p27 Kip1 Ameliorates Progression of Diabetic Nephropathy
M Awazu, S Omori, K Ishikura, M Hida, H Fujita
Journal of the American Society of Nephrology : JASN 2003
Delayed Treatment with Lithospermate B Attenuates Experimental Diabetic Renal Injury
GE Lee, H Ha, M Jung, H Li, SW Hong, BS Cha, HC Lee, YD Cho
Journal of the American Society of Nephrology : JASN 2003
Inhibiting albumin glycation in vivo ameliorates glomerular overexpression of TGF-beta1
MP Cohen, FN Ziyadeh, SW Hong, CW Shearman, E Hud, GT Lautenslager, MC la Cruz, S Chen
Kidney International 2002
Prevention of diabetic nephropathy in rats by prostaglandin E receptor EP1-selective antagonist
H Makino, I Tanaka, M Mukoyama, A Sugawara, K Mori, S Muro, T Suganami, K Yahata, R Ishibashi, S Ohuchida, T Maruyama, S Narumiya, K Nakao
Journal of the American Society of Nephrology : JASN 2002
Response of mesangial cells to low-density lipoprotein and angiotensin II in diabetic (OLETF) rats
M Okada, T Takemura, H Yanagida, K Yoshioka
Kidney International 2002
Independent Regulation of Transforming Growth Factor-β1 Transcription and Translation by Glucose and Platelet-Derived Growth Factor
D Fraser, L Wakefield, A Phillips
The American Journal of Pathology 2002
An increase in the cell component of the cortical interstitium antedates interstitial fibrosis in type 1 diabetic patients1
A Katz, ML Caramori, S Sisson-Ross, T Groppoli, JM Basgen, M Mauer
Kidney International 2002
Diabetic nephropathy: It's in the numbers
AB Fogo
Kidney International 2002
Renal Function Tests on Diabetes-Induced and Non-Induced APA Hamsters
T INENAGA, E NISHIDA, S KAWAMURA, Y YOSHIKAWA
Experimental Animals 2002
Diabetes-induced changes in responsiveness of rat bladder and vas deferens to peptides in vitro: susceptibility to reversal by insulin
AH Cardozo, DA Cabrini, MM Campos, GA Rae, JP Huidobro-Toro, JB Calixto
Canadian Journal of Physiology and Pharmacology 2002
Independent regulation of transforming growth factor-beta1 transcription and translation by glucose and platelet-derived growth factor
D Fraser, L Wakefield, A Phillips
The American Journal of Pathology 2002
Decorin suppresses transforming growth factor-beta-induced expression of plasminogen activator inhibitor-1 in human mesangial cells through a mechanism that involves Ca2+-dependent phosphorylation of Smad2 at serine-240
N Abdel-Wahab, SJ Wicks, RM Mason, A Chantry
Biochemical Journal 2002
Beraprost sodium, prostacyclin analogue, attenuates glomerular hyperfiltration and glomerular macrophage infiltration by modulating ecNOS expression in diabetic rats
T Yamashita, K Shikata, M Matsuda, S Okada, D Ogawa, H Sugimoto, J Wada, H Makino
Diabetes Research and Clinical Practice 2002
Sarpogrelate hydrochloride, a serotonin2A receptor antagonist, reduces albuminuria in diabetic patients with early-stage diabetic nephropathy
T Takahashi, M Yano, J Minami, T Haraguchi, N Koga, K Higashi, S Kobori
Diabetes Research and Clinical Practice 2002
Goto-Kakizaki rat is protected from proteinuria after induction of anti-Thy1 nephritis
SG Riley, RA Evans, M Davies, J Floege, AO Phillips
American Journal of Kidney Diseases 2002
Podocyte Number in Normotensive Type 1 Diabetic Patients With Albuminuria
KE White, RW Bilous, SM Marshall, ME Nahas, G Remuzzi, G Piras, SD Cosmo, G Viberti
Diabetes 2002
The Early Natural History of Nephropathy in Type 1 Diabetes: II. Early Renal Structural Changes in Type 1 Diabetes
K Drummond, M Mauer
Diabetes 2002
Cellular Basis of Diabetic Nephropathy: II. The Transforming Growth Factor-  System and Diabetic Nephropathy Lesions in Type 1 Diabetes
C Huang, Y Kim, ML Caramori, AJ Fish, SS Rich, ME Miller, GB Russell, M Mauer
Diabetes 2002
The Early Natural History of Nephropathy in Type 1 Diabetes: I. Study Design and Baseline Characteristics of the Study Participants
M Mauer, K Drummond
Diabetes 2002
The Genetics of Hypertension Modifies the Renal Cell Replication Response Induced by Experimental Diabetes
LA Silveira, CE Bacchi, GA Pinto, JB de Faria
Diabetes 2002
Proximal tubular epithelial cell integrins respond to high glucose by altered cell-matrix interactions and differentially regulate matrixin expression
Panagiotis M Karamessinis, Athina K Tzinia, Paraskevi V Kitsiou, William G Stetler-Stevenson, Alfred F Michael, Wei-Wei Fan, Bing Zhou, Lukas H Margaritis, Effie C Tsilibary
Laboratory Investigation 2002
ACE-I and ARBs in early diabetic nephropathy
M Mauer, B Zinman, R Gardiner, KN Drummond, S Suissa, SM Donnelly, TD Strand, MS Kramer, R Klein, AR Sinaiko
Journal of Renin-Angiotensin-Aldosterone System 2002
TGF-β1 is an Autocrine Mediator of Renal Tubular Epithelial Cell Growth and Collagen IV Production
JP Grande, GM Warner, HJ Walker, AN Yusufi, J Cheng, CE Gray, JB Kopp, KA Nath
Experimental biology and medicine (Maywood, N.J.) 2002
Renal Pathology in Fabry Disease
J Alroy, S Sabnis, JB Kopp
Journal of the American Society of Nephrology : JASN 2002
Diabetic Renal-Retinal Syndrome
EA Friedman, FA LEsperance
2002
Estimating Mean Glomerular Volume Using Two Arbitrary Parallel Sections
B Najafian, JM Basgen, M Mauer
Journal of the American Society of Nephrology : JASN 2002
Effects of Cigarette Smoking on Glomerular Structure and Function in Type 2 Diabetic Patients
B Baggio, A Budakovic, MD Vestra, A Saller, M Bruseghin, P Fioretto
Journal of the American Society of Nephrology : JASN 2002
Role of immunocompetent cells in nonimmune renal diseases
B Rodriguez-Iturbe, H Pons, J Herrera-Acosta, RJ Johnson
Kidney International 2001
PDGF signal transduction inhibition ameliorates experimental mesangial proliferative glomerulonephritis1
RE Gilbert, DJ Kelly, T Mckay, S Chadban, PA Hill, ME Cooper, RC Atkins, DJ Nikolic-Paterson
Kidney International 2001
The meaning of microalbuminuria in type 1 diabetes: The need for a new paradigm
SG Adler, CC Nast
Current Diabetes Reports 2001
Quantitative immunoelectron microscopy of type VI collagen in glomeruli in type I diabetic patients
T Moriya, TJ Groppoli, Y Kim, M Mauer
Kidney International 2001
Glucose Alters the Susceptibility of Mesangial Cells to Contrast Media
M Wasaki, J Sugimoto, K Shirota
Investigative Radiology 2001
Pathogenesis of diabetic nephropathy: focus on transforming growth factor-β and connective tissue growth factor
OV Sakharova, MW Taal, BM Brenner
Current Opinion in Nephrology and Hypertension 2001
Lessons Learned From More Than 1,000 Pancreas Transplants at a Single Institution
DE Sutherland, RW Gruessner, DL Dunn, AJ Matas, A Humar, R Kandaswamy, SM Mauer, WR Kennedy, FC Goetz, RP Robertson, AC Gruessner, JS Najarian
Annals of Surgery 2001
Glycated albumin stimulates TGF-beta1 production and protein kinase C activity in glomerular endothelial cells1
S Chen, MP Cohen, GT Lautenslager, CW Shearman, FN Ziyadeh
Kidney International 2001
Progression of diabetic nephropathy
P Hovind, P Rossing, L Tarnow, UM Smidt, HH Parving
Kidney International 2001
Low-molecular-weight heparin prevents high glucose- and phorbol ester-induced TGF-beta1 gene activation
C Weigert, K Brodbeck, HU Haring, G Gambaro, ED Schleicher
Kidney International 2001
Risk predictors in patients with diabetic nephropathy
P Fioretto, ML Caramori, M Vestra, M Mauer
Current Diabetes Reports 2001
Increases in Renal ε-(γ-Glutamyl)-Lysine Crosslinks Result from Compartment-Specific Changes in Tissue Transglutaminase in Early Experimental Diabetic Nephropathy: Pathologic Implications
NJ Skill, M Griffin, AM el Nahas, T Sanai, JL Haylor, M Fisher, MF Jamie, NN Mould, TS Johnson
Laboratory Investigation 2001
p38 MAPK and MAPK kinase 3/6 mRNA and activities are increased in early diabetic glomeruli
SW Kang, SG Adler, J Lapage, R Natarajan
Kidney International 2001
CONNECTIVE TISSUE GROWTH FACTOR AND ITS REGULATION: A NEW ELEMENT IN DIABETIC GLOMERULOSCLEROSIS
BL Riser, P Cortes
Renal Failure 2001
THE KEY ROLE OF THE TRANSFORMING GROWTH FACTOR-β SYSTEM IN THE PATHOGENESIS OF DIABETIC NEPHROPATHY
S Chen, SW Hong, MC Cruz, M Isono, A Casaretto, FN Ziyadeh
Renal Failure 2001
Lessons learned from more than 1,000 pancreas transplants at a single institution
DE Sutherland, RW Gruessner, DL Dunn, AJ Matas, A Humar, R Kandaswamy, SM Mauer, WR Kennedy, FC Goetz, RP Robertson, AC Gruessner, JS Najarian
Annals of Surgery 2001
An oral adsorbent ameliorates renal overload of indoxyl sulfate and progression of renal failure in diabetic rats
I Aoyama, T Niwa
American Journal of Kidney Diseases 2001
Aminoguanidine ameliorates overexpression of prosclerotic growth factors and collagen deposition in experimental diabetic nephropathy
DJ Kelly, RE Gilbert, AJ Cox, T Soulis, G Jerums, ME Cooper
Journal of the American Society of Nephrology : JASN 2001
Asian multicenter trials on urinary type IV collagen in patients with diabetic nephropathy
Y Tomino, S Suzuki, C Azushima, I Shou, T Iijima, M Yagame, LN Wang, HC Chen, KN Lai, SY Tan, MJ Kim
Journal of Clinical Laboratory Analysis 2001
Antisense GLUT-1 protects mesangial cells from glucose induction of GLUT-1 and fibronectin expression
CW Heilig, JI Kreisberg, S Freytag, T Murakami, Y Ebina, L Guo, K Heilig, R Loberg, X Qu, Y Jin, D Henry, FC Brosius
American journal of physiology. Renal physiology 2001
Renal fibrosis in diabetic and aortic-constricted hypertensive rats
B Gallego, MA Arévalo, O Flores, JM López-Novoa, F Pérez-Barriocanal
American Journal of Physiology - Regulatory, Integrative and Comparative Physiology 2001
Glycohemoglobin: A Primary Predictor of the Development or Reversal of Complications of Diabetes Mellitus
U Krishnamurti, MW Steffes
Clinical chemistry 2001
Syndecan‐4 up‐regulation in proliferative renal disease is related to microfilament organization
S Yung, A Woods, TM Chan, M Davies, JD Williams, JR Couchman
The FASEB Journal 2001
Risk predictors in patients with diabetic nephropathy
P Fioretto, ML Caramori, MD Vestra, M Mauer
Current Diabetes Reports 2001
Relationship between fascicle size and perineurial collagen IV content in diabetic and control human peripheral nerve
PE Williams, A Lowry, R Hill, E Masson
Histopathology 2000
Deciphering diabetic nephropathy: progress using genetic strategies
SG Adler, M Pahl, MF Seldin
Current Opinion in Nephrology and Hypertension 2000
Causes of albuminuria in patients with type 2 diabetes without diabetic retinopathy
PK Christensen, S Larsen, T Horn, S Olsen, HH Parving
Kidney International 2000
Selecting antihypertensive therapy in the pregnant woman with diabetes mellitus
DL Conway, O Langer
The Journal of Maternal-Fetal Medicine 2000
Alterations of the Rat Mesentery Vasculature in Experimental Diabetes
K Arshi, M Bendayan, LD Ghitescu
Laboratory Investigation 2000
Role of the hexosamine biosynthetic pathway in diabetic nephropathy
ED Schleicher, C Weigert
Kidney International 2000
Role of mitogen-activated protein kinases as downstream effectors of transforming growth factor-beta in mesangial cells
K Inoki, M Haneda, T Ishida, H Mori, S Maeda, D Koya, T Sugimoto, R Kikkawa
Kidney International 2000
Amadori-glycated albumin in diabetic nephropathy: Pathophysiologic connections
S Chen, MP Cohen, FN Ziyadeh
Kidney International 2000
Effects of diabetes and hypertension on glomerular transforming growth factor-beta receptor expression
MJ Kang, A Ingram, H Ly, K Thai, JW Scholey
Kidney International 2000
Evolution of incipient nephropathy in type 2 diabetes mellitus
KV Lemley, I Abdullah, BD Myers, TW Meyer, K Blouch, WE Smith, PH Bennett, RG Nelson
Kidney International 2000
Troglitazone halts diabetic glomerulosclerosis by blockade of mesangial expansion1
KJ McCarthy, RE Routh, W Shaw, K Walsh, TC Welbourne, JH Johnson
Kidney International 2000
Transforming growth factor beta contributes to progressive diabetic nephropathy
WB Reeves, TE Andreoli
Proceedings of the National Academy of Sciences 2000
Long-term prevention of renal insufficiency, excess matrix gene expression, and glomerular mesangial matrix expansion by treatment with monoclonal antitransforming growth factor-beta antibody in db/db diabetic mice
FN Ziyadeh, BB Hoffman, DC Han, MC la Cruz, SW Hong, M Isono, S Chen, TA McGowan, K Sharma
Proceedings of the National Academy of Sciences 2000
Molecular mechanism of diabetic nephropathy
R Lehmann, ED Schleicher
Clinica Chimica Acta 2000
Increased tubuloglomerular feedback reactivity is associated with increased NO production in the streptozotocin-diabetic rat
C Thorup
Journal of Diabetes and its Complications 2000
Octreotide administration in diabetic rats: effects on renal function and morphology
T Usenmez
Journal of Diabetes and its Complications 2000
Inhibition of nitric oxide synthase activity by early and advanced glycation end products in cultured rabbit proximal tubular epithelial cells
P Verbeke, M Perichon, B Friguet, H Bakala
Biochimica et Biophysica Acta 2000
Amelioration of accelerated diabetic mesangial expansion by treatment with a PKC β inhibitor in diabetic db/db mice, a rodent model for type 2 diabetes
D Koya, M Haneda, H Nakagawa, K Isshiki, H Sato, S Maeda, T Sugimoto, H Yasuda, A Kashiwagi, DK Ways, GL King, R Kikkawa
The FASEB Journal 2000
The Kidney and Hypertension in Diabetes Mellitus
CE Mogensen
2000
Follow‐up study of glomerular dimensions and cortical interstitium in microalbuminuric type 1 diabetic patients with or without antihypertensive treatment
R Østerby, HJ Bangstad, S Rudberg
Nephrology Dialysis Transplantation 2000
AP-1 Proteins Mediate Hyperglycemia-Induced Activation of the Human TGF-β1 Promoter in Mesangial Cells
C Weigert, U Sauer, K Brodbeck, A Pfeiffer, HU Häring, ED Schleicher
Journal of the American Society of Nephrology : JASN 2000
The Decorin High Glucose Response Element and Mechanism of Its Activation in Human Mesangial Cells
NA Wahab, S Parker, JD Sraer, RM Mason
Journal of the American Society of Nephrology : JASN 2000
Type 2 Diabetic Patients with Nephropathy Show Structural—Functional Relationships that Are Similar to Type 1 Disease
KE White, RW Bilous
Journal of the American Society of Nephrology : JASN 2000
Glycosaminoglycans: Use in Treatment of Diabetic Nephropathy
G Gambaro, FJ Woude
Journal of the American Society of Nephrology : JASN 2000
Glycosaminoglycan Therapy Prevents TGF-β1 Overexpression and Pathologic Changes in Renal Tissue of Long-Term Diabetic Rats
M Ceol, G Gambaro, U Sauer, B Baggio, F Anglani, M Forino, S Facchin, L Bordin, C Weigert, A Nerlich, ED Schleicher
Journal of the American Society of Nephrology : JASN 2000
TGF-beta receptor expression and binding in rat mesangial cells: Modulation by glucose and cyclic mechanical strain
BL Riser, S Ladson-Wofford, A Sharba, P Cortes, K Drake, CJ Guerin, J Yee, ME Choi, PR Segarini, RG Narins
Kidney International 1999
Vascular cell adhesion molecule-l expression in the renal interstitium of diabetic KKAy mice
K Ina
Diabetes Research and Clinical Practice 1999
High glucose increases growth and collagen synthesis in cultured human tubulointerstitial cells
SC Jones, HJ Saunders, CA Pollock
Diabetic Medicine 1999
Effect of diabetes and aminoguanidine therapy on renal advanced glycation end-product binding
S Youssef, DT Nguyen, T Soulis, S Panagiotopoulos, G Jerums, ME Cooper
Kidney International 1999
The tubulointerstitium in progressive diabetic kidney disease: More than an aftermath of glomerular injury?
RE Gilbert, ME Cooper
Kidney International 1999
TGF-beta1 stimulates glucose uptake by enhancing GLUT1 expression in mesangial cells
K Inoki, M Haneda, S Maeda, D Koya, R Kikkawa
Kidney International 1999
Effect of glucose on stress-activated protein kinase activity in mesangial cells and diabetic glomeruli
MJ Kang, X Wu, H Ly, K Thai, JW Scholey
Kidney International 1999
Molecular mechanisms of diabetic renal hypertrophy
G Wolf, FN Ziyadeh
Kidney International 1999
Renal disease and hypertension in non–insulin-dependent diabetes mellitus
N Ismail, B Becker, P Strzelczyk, E Ritz
Kidney International 1999
Renal proximal tubular cell fibronectin accumulation in response to glucose is polyol pathway dependent
K Morrisey, R Steadman, JD Williams, AO Phillips
Kidney International 1999
Melatonin and taurine reduce early glomerulopathy in diabetic rats
H Ha, MR Yu, KH Kim
Free radical biology & medicine 1999
Diabetic nephropathy
HA Ibrahim, JP Vora
Best Practice & Research Clinical Endocrinology & Metabolism 1999
Augmentation of kidney injury by basic fibroblast growth factor or platelet-derived growth factor does not induce progressive diabetic nephropathy in the Goto Kakizaki model of non-insulin-dependent diabetes
SG Riley, R Steadman, JD Williams, J Floege, AO Phillips
Journal of Laboratory and Clinical Medicine 1999
EFFECT OF INTENSIVE INSULIN THERAPY ON PROGRESSION OF OVERT NEPHROPATHY IN PATIENTS WITH TYPE 1 DIABETES MELLITUS
TT FACE, EO MD, GM FACE, AR FACE, MA MS, MM MD, PP MD, RM MS
Endocrine Practice 1999
Cloning and Characterization of ZNF236, a Glucose-Regulated Kruppel-like Zinc-Finger Gene Mapping to Human Chromosome 18q22–q23
DI Holmes, NA Wahab, RM Mason
Genomics 1999
A Study of Tamm-Horsfall Protein Excretion in Hypertensive Patients and Type 1 Diabetic Patients
O Torffvit, CD Agardh, T Thulin
Scandinavian Journal of Urology and Nephrology 1999
Regulation of angiotensin II receptors and PKC isoforms by glucose in rat mesangial cells
F Amiri, R Garcia
American journal of physiology. Renal physiology 1999
Renal Changes on Hyperglycemia and Angiotensin-Converting Enzyme in Type 1 Diabetes
M Marre, B Bouhanick, G Berrut, Y Gallois, JJ Jeune, G Chatellier, J Menard, F Alhenc-Gelas
Hypertension 1999
Molecular and Cellular Pediatric Endocrinology
S Handwerger
1999
Favorable Treatment Outcome with Neutralizing anti Transforming Growth Factor I:} Antibodies in Experimental Diabetic Kidney Disease
DC Han, FN Ziyadeh
Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis 1999
Stereologic Methods and Their Application in Kidney Research
JR Nyengaard
Journal of the American Society of Nephrology : JASN 1999
Mechanisms of Mitogen-Activated Protein Kinase Activation in Experimental Diabetes
M Awazu, K Ishikura, M Hida, M Hoshiya
Journal of the American Society of Nephrology : JASN 1999
Expression of Megsin mRNA, a Novel Mesangium-Predominant Gene, in the Renal Tissues of Various Glomerular Diseases
D Suzuki, T Miyata, M Nangaku, H Takano, N Saotome, M Toyoda, Y Mori, SY Zhang, R Inagi, M Endoh, K Kurokawa, H Sakai
Journal of the American Society of Nephrology : JASN 1999
High Glucose Stimulates Proliferation and Collagen Type I Synthesis in Renal Cortical Fibroblasts: Mediation by Autocrine Activation of TGF-β
DC Han, M Isono, BB Hoffman, FN Ziyadeh
Journal of the American Society of Nephrology : JASN 1999
Abnormal renal and hepatic glucose metabolism in type 2 diabetes mellitus
C Meyer, M Stumvoll, V Nadkarni, J Dostou, A Mitrakou, J Gerich
Journal of Clinical Investigation 1998
Effects of oral antihyperglycemic agents on extracellular matrix synthesis by mesangial cells
P Cortes, BL Riser, K Asano, A Rodríguez-Barbero, RG Narins, J Yee
Kidney International 1998
Follow-up study on urinary type IV collagen in patients with early stage diabetic nephropathy
T Iijima, S Suzuki, K Sekizuka, T Hishiki, M Yagame, K Jinde, N Saotome, D Suzuki, H Sakai, Y Tomino
Journal of Clinical Laboratory Analysis 1998
Differential response of glomerular epithelial and mesangial cells after subtotal nephrectomy
GS Lee, CC Nast, SC Peng, A Artishevsky, CG Ihm, R Guillermo, PS Levin, RJ Glassock, J LaPage, SG Adler
Kidney International 1998
Serotonin enhances the production of type IV collagen by human mesangial cells
M Kasho, M Sakai, T Sasahara, Y Anami, T Matsumura, T Takemura, H Matsuda, S Kobori, M Shichiri
Kidney International 1998
Human glomerular structure under normal conditions and in isolated glomerular disease
A Bohle, B Aeikens, A Eenboom, L Fronholt, WR Plate, JC Xiao, A Greschniok, M Wehrmann
Kidney International 1998
DNA binding of activator protein-1 is increased in human mesangial cells cultured in high glucose concentrations
WA Wilmer, FG Cosio
Kidney International 1998
Ddiabetic nephropathy as a of revrsibility of established renal lesions
P Fioretto, Y Kim, M Mauer
Current Opinion in Nephrology and Hypertension 1998
Sequential effects of high glucose on mesangial cell transforming growth factor-β1 and fibronectin synthesis
JH Oh, H Ha, MR Yu, HB Lee
Kidney International 1998
Evidence for a functional Hepatocyte Growth Factor receptor in human mesangial cells
NC Kallincos, AN Pollard, JJ Couper
Regulatory Peptides 1998
Regulation of gene expression by alternative polyadenylation and mRNA instability in hyperglycaemic mesangial cells
NA Wahab, J Gibbs, RM Mason
Biochemical Journal 1998
Pathophysiology of diabetic nephropathy
ME Cooper, RE Gilbert, M Epstein
Metabolism 1998
Expression of Cysteine Proteinases and Their Inhibitor, Cystatin β, in Cultured Rat Mesangial Cells
Y Makita, K Ishidoh, E Kominami, K Funabiki, H Koide, Y Tomino
Journal of Diabetes and its Complications 1998
Anti-Glycated Albumin Therapy Ameliorates Early Retinal Microvascular Pathology in db/db Mice
RS Clements, WG Robison, MP Cohen
Journal of Diabetes and its Complications 1998
Effects of perindopril on renal histomorphometry in diabetic subjects with microalbuminuria: A 3-year placebo-controlled biopsy study
A Nankervis, K Nicholls, G Kilmartin, P Allen, S Ratnaike, FI Martin
Metabolism 1998
Role of angiotensin-converting enzyme inhibition in glucose metabolism and renal injury in diabetes
MT Velasquez, SJ Bhathena, JS Striffler, N Thibault, E Scalbert
Metabolism 1998
Effect of vascular endothelial growth factor on nitric oxide production by cultured rat mesangial cells
H Trachtman, S Futterweit, N Franki, PC Singhal
Biochemical and Biophysical Research Communications 1998
Proximal tubular basement membrane width in insulin-dependent diabetes mellitus
PL Brito, P Fioretto, K Drummond, Y Kim, MW Steffes, JM Basgen, S Sisson-Ross, M Mauer
Kidney International 1998
Elevated glucose increases mesangial cell sensitivity to insulin-like growth factor I
MJ Horney, DW Shirley, DT Kurtz, SA Rosenzweig
American journal of physiology. Renal physiology 1998
Follow‐up study on urinary type IV collagen in patients with early stage diabetic nephropathy
Iijima T, Suzuki S, Sekizuka K, Hishiki T, Yagame M, Jinde K, Saotome N, Suzuki D, Sakai H, Tomino Y
Journal of Clinical Laboratory Analysis 1998
Significance of urinary type IV collagen in patients with diabetic nephropathy using a highly sensitive one‐step sandwich enzyme immunoassay
Yagame M, Suzuki D, Jinde K, Saotome N, Sato H, Noguchi M, Sakai H, Kuramoto T, Sekizuka K, Iijima T, Suzuki S, Tomino Y
Journal of Clinical Laboratory Analysis 1998
Podocyte loss and progressive glomerular injury in type II diabetes
ME Pagtalunan, PL Miller, S Jumping-Eagle, RG Nelson, BD Myers, HG Rennke, NS Coplon, L Sun, TW Meyer
Journal of Clinical Investigation 1997
Characterization of protein kinase C beta isoform activation on the gene expression of transforming growth factor-beta, extracellular matrix components, and prostanoids in the glomeruli of diabetic rats
D Koya, MR Jirousek, YW Lin, H Ishii, K Kuboki, GL King
Journal of Clinical Investigation 1997
Significance of urinary type IV collagen in patients with diabetic nephropathy using a highly sensitive one-step sandwich enzyme immunoassay
M Yagame, D Suzuki, K Jinde, N Saotome, H Sato, M Noguchi, H Sakai, T Kuramoto, K Sekizuka, T Iijima, S Suzuki, Y Tomino
Journal of Clinical Laboratory Analysis 1997
Efficient morphometric analysis of glomerular mesangium in insulin-dependent diabetic patients with early nephropathy
JM MacLeod, KE White, H Tate, RW Bilous
Kidney International 1997
Nonenzymatically glycated albumin (Amadori adducts) enhances nitric oxide synthase activity and gene expression in endothelial cells
A Amore, P Cirina, S Mitola, L Peruzzi, B Gianoglio, I Rabbone, C Sacchetti, F Cerutti, C Grillo, R Coppo
Kidney International 1997
A pilot study of the effect of the glycosaminoglycan sulodexide on microalbuminuria in type I diabetic patients
M Szelanowska, A Poplawska, J Jopdska, I Kinalska, M Grimaldi
Current Medical Research and Opinion 1997
Myofibroblasts and arteriolar sclerosis in human diabetic nephropathy
E Pedagogos, T Hewitson, I Fraser, K Nicholls, G Becker
American Journal of Kidney Diseases 1997
Identification of Glucose-Regulated Genes in Human Mesangial Cells by mRNA Differential Display
DI Holmes, NA Wahab, RM Mason
Biochemical and Biophysical Research Communications 1997
Protective effect of d-α-tocopherol on the function of human mesangial cells exposed to high glucose concentrations
H Tada, H Ishii, S Isogai
Metabolism 1997
Renal mortality associated with non-insulin-dependent diabetes mellitus
P Kilaru
Journal of Diabetes and its Complications 1997
Alterations in Human Glomerular Epithelial Cells Interacting with Nonenzymatically Glycosylated Matrix
U Krishnamurti, E Rondeau, JD Sraer, AF Michael, EC Tsilibary
The Journal of biological chemistry 1997
Methods of renal blood flow measurement
LS Young, MC Regan, MK Barry, JG Geraghty, JM Fitzpatrick
Urological Research 1996
Focal segmental glomerulosclerosis
I Ichikawa, A Fogo
Pediatric Nephrology 1996
Effects of early insulin treatment on ultrastructural changes of glomeruli in diabetic rats revealed by the quick-freezing and deep-etching method
T Moriya, S Ohno, K Tanaka, Y Fujii, Y Yajima
Diabetologia 1996
Production of hyaluronan by glomerular mesangial cells in response to fibronectin and platelet-derived growth factor
ME Dunlop, S Clark, P Mahadevan, E Muggli, RG Larkins
Kidney International 1996
The three-dimensional ultrastructure of diabetic glomeruli revealed by the quick-freezing and deep-etching method
K Tanaka, T Moriya, S Ohno, Y Yajima
Medical Electron Microscopy 1996
RENAL SYNDROMES IN DIABETES
EA Friedman
Endocrinology & Metabolism Clinics of North America 1996
Phosphorylation of cAMP responsive element binding protein after treatment of mesangial cells with high glucose plus TGFβ or PMA
JI Kreisberg, RA Radnik, SH Kreisberg
Kidney International 1996
Urinary type IV collagen as a marker for early diabetic nephropathy
S Kado
Diabetes Research and Clinical Practice 1996
Extracellular matrix, growth factors and their interactions in the pathogenesis of diabetic kidney disease
RE GILBERT, ME COOPER, G JERUMS
Nephrology 1996
Growth phenotype of cultured skin fibroblasts from IDDM patients with and without nephropathy and overactivity of the Na+/H+ antiporter
A Lurbe, P Fioretto, M Mauer, MS LaPointe, D Batlle
Kidney International 1996
Effects of aminoguanidine in preventing experimental diabetic nephropathy are related to the duration of treatment
T Soulis, ME Cooper, D Vranes, R Bucala, G Jerums
Kidney International 1996
Prevention of early glomerulopathy with tolrestat in the streptozotocin-induced diabetic rat
SM Donnelly, JT Huang, XP Zhou, CI Whiteside
Biochemistry and Cell Biology 1996
Urinary Fibronectin Excretion in Streptozotocin-Diabetic Rats
E Jonas, I Jäckle-Meyer, B Szukics, H Stolte
Clinical Chemistry and Laboratory Medicine 1996
Effect of Matrix Glycation on Expression of Type IV Collagen, MMP-2, MMP-9 and TIMP-1 by Human
SS Anderson, K Wu, H Nagase, WG Stettler-Stevenson, Y Kim, EC Tsilibary
Cell Communication and Adhesion 1996
The changing course of diabetic nephropathy: Low-density lipoprotein cholesterol and blood pressure correlate with regression of proteinuria
D Ellis, C Lloyd, DJ Becker, KY Forrest, TJ Orchard
American Journal of Kidney Diseases 1996
Modulation of neutral protease expression in human mesangial cells by hyperglycaemic culture
NA Wahab, RM Mason
Biochemical Journal 1996
High glucose concentration induces the overexpression of transforming growth factor-beta through the activation of a platelet-derived growth factor loop in human mesangial cells
SD Paolo, L Gesualdo, E Ranieri, G Grandaliano, FP Schena
The American Journal of Pathology 1996
Pathobiochemistry of combined diabetes and atherosclerosis studied on a novel animal model. The hyperlipemic-hyperglycemic hamster
M Simionescu, D Popov, A Sima, M Hasu, G Costache, S Faitar, A Vulpanovici, C Stancu, D Stern, N Simionescu
The American Journal of Pathology 1996
Expression of extracellular matrix molecules in human mesangial cells in response to prolonged hyperglycaemia
NA Wahab, K Harper, RM Mason
Biochemical Journal 1996
Cyclic stretching force selectively up-regulates transforming growth factor-beta isoforms in cultured rat mesangial cells
BL Riser, P Cortes, C Heilig, J Grondin, S Ladson-Wofford, D Patterson, RG Narins
The American Journal of Pathology 1996
Development and Progression of Renal Disease in Pima Indians with Non-Insulin-Dependent Diabetes Mellitus
RG Nelson, PH Bennett, GJ Beck, M Tan, WC Knowler, WE Mitch, GH Hirschman, BD Myers
New England Journal of Medicine 1996
Changes of extracellular matrix in a baboon (Papio hamadryas) model of insulin dependent diabetes: studies using electron microscopy and X-ray diffraction techniques
S Heffernan, V James, R Zilkens, P Kirwan, A Birrell, S McLennan, A Hennessy, A Gillin, J Horvath, D Tiller, D Yue, J Turtle
Diabetes Research and Clinical Practice 1996
Immunofluorescence staining of renal biopsy samples in patients with diabetic nephropathy in non-insulin-dependent diabetes mellitus using monoclonal antibody to reduced glycated lysine
D Suzuki
Journal of Diabetes and its Complications 1996
DIABETIC NEPHROPATHY AND PREGNANCY
JL Kitzmiller, CA Combs
Obstetrics and Gynecology Clinics of North America 1996
Complementary vascular-protective actions of magnesium and taurine: A rationale for magnesium taurate
MF McCarty
Medical Hypotheses 1996
Evaluation of glomerular lesion and abnormal urinary findings in OLETF rats resulting from a long-term diabetic state
Y Fukuzawa, Y Watanabe, D Inaguma, N Hotta
Journal of Laboratory and Clinical Medicine 1996
Current Issues in Treating the Hypertensive Patient with Diabetes: Focus on Diabetic Nephropathy
MJ Cziraky, IV Mehra, MD Wilson, GL Bakris
The Annals of pharmacotherapy 1996
Effects of heparin on renal morphology and albuminuria in experimental diabetes
SM Marshall, KW Hansen, R Osterby, J Frystyk, H Orskov, A Flyvbjerg
American journal of physiology. Endocrinology and metabolism 1996
Prevention of decline in renal function in the diabetic db/db mouse
MP Cohen, RS Clements, JA Cohen, CW Shearman
Diabetologia 1996
Effect of high glucose on the expression of cathepsin B, L and cystatin β in cultured rat mesangial cells
Y Makita
Juntendo Medical Journal 1996
Prevention of diabetic nephropathy in db/db mice with glycated albumin antagonists. A novel treatment strategy
MP Cohen, K Sharma, Y Jin, E Hud, VY Wu, J Tomaszewski, FN Ziyadeh
Journal of Clinical Investigation 1995
Overexpression of glucose transporters in rat mesangial cells cultured in a normal glucose milieu mimics the diabetic phenotype
CW Heilig, LA Concepcion, BL Riser, SO Freytag, M Zhu, P Cortes
Journal of Clinical Investigation 1995
Regional renal blood flow in normal and disease states
MC Regan, LS Young, J Geraghty, JM Fitzpatrick
Urological Research 1995
Regulation of aldose reductase gene expression in renal cortex and medulla of rats
RI Dorin, VO Shah, DL Kaplan, BS Vela, PG Zager
Diabetologia 1995
Diabetes Mellitus and Hypertension, Emerging Therapeutic Perspectives
JR Sowers, M Epstein
Cardiovascular Drug Reviews 1995
Cyclosporine associated lesions in native kidneys of diabetic pancreas transplant recipients
P Fioretto, MW Steffes, MJ Mihatsch, EH Strøm, DE Sutherland, M Mauer
Kidney International 1995
Renal Fluid and Electrolyte Handling in Streptozotocin-Diabetic Rats
CT Musabayane, CE Ndhlovu, RJ Balment
Renal Failure 1995
Expression of growth-related protooncogenes during diabetic renal hypertrophy
SJ Shankland, JW Scholey, H Ly, K Thai
Kidney International 1995
Progression of overt nephropathy in non-insulin-dependent diabetes
BD Myers, RG Nelson, M Tan, GJ Beck, PH Bennett, WC Knowler, K Blouch, WE Mitch
Kidney International 1995
Proteoglycan synthesis by bovine myocardial endothelial cells is increased by long-term exposure to high concentrations of glucose
DJ Klein, RM Cohen, Z Rymaszewski
Journal of Cellular Physiology 1995
Immunohistochemical staining of renal biopsy samples in patients with diabetic nephropathy in non-insulin dependent diabetes mellitus using monoclonal antibody to advanced glycation end products
D SUZUKI, M YAGAME, R NAKA, K JINDE, M ENDOH, Y NOMOTO, H SAKAI, N ARAKI, S HORIUCHI
Nephrology 1995
Induction of nodular sclerosis by insulin in rat mesangial cells in vitro: Studies of collagen
CK Abrass, D Spicer, GJ Raugi
Kidney International 1995
PDGF and TGF-β mediate collagen production by mesangial cells exposed to advanced glycosylation end products
DC Throckmorton, AP Brogden, B Min, H Rasmussen, M Kashgarian
Kidney International 1995
Extracellular Matrix Proteins as Early Markers in Diabetic Nephropathy
I Jäckle-Meyer, B Szukics, K Neubauer, V Metze, R Petzoldt, H Stolte
Clinical Chemistry and Laboratory Medicine 1995
Sequential renal biopsies in insulin-dependent diabetic patients: Structural factors associated with clinical progression
P Fioretto, MW Steffes, DE Sutherland, M Mauer
Kidney International 1995
Diabetic nephropathy. Mechanisms of mesangial matrix expansion
CK Abrass
The Western journal of medicine 1995
Elevated D-glucose concentrations modulate TGF-beta 1 synthesis by human cultured renal proximal tubular cells. The permissive role of platelet-derived growth factor
AO Phillips, R Steadman, N Topley, JD Williams
The American Journal of Pathology 1995
Intervention in diabetic vascular disease by modulation of growth factors
O Serri, G Renier
Metabolism 1995
Extracellular matrix and its interactions in the diabetic kidney: A molecular biological approach
RE Gilbert, A Cox, M Dziadek, ME Cooper, G Jerums
Journal of Diabetes and its Complications 1995
Hypertension in Diabetic Patients: An Update of Interventional Studies to Preserve Renal Function
DD Hoelscher, MR Weir, GL Bakris
The Journal of Clinical Pharmacology 1995
Glucose entry into rat mesangial cells is mediated by both Na+-coupled and facilitative transporters
M Wakisaka, Q He, MJ Spiro, RG Spiro
Diabetologia 1995
Glomerular epithelial foot processes and filtration slits in IDDM patients
SF Bjrn, , KF Hanssen, G Nyberg, JD Walker, GC Viberti, R sterby
Diabetologia 1995
Tubulointerstitial and Cystic Disease of the Kidney
SM Dodd
1995
Stimulation of collagen gene expression and protein synthesis in murine mesangial cells by high glucose is mediated by autocrine activation of transforming growth factor-beta
FN Ziyadeh, K Sharma, M Ericksen, G Wolf
Journal of Clinical Investigation 1994
Structural basis for reduced glomerular filtration capacity in nephrotic humans
MC Drumond, B Kristal, BD Myers, WM Deen
Journal of Clinical Investigation 1994
Structural-functional correlations of diabetic nephropathy
SM Mauer
Kidney International 1994
Effects of matrix glycation on mesangial cell adhesion, spreading and proliferation
SS Anderson, Y Kim, EC Tsilibary
Kidney International 1994
Glomerular distribution of type IV collagen in diabetes by high resolution quantitative immunochemistry
D Zhu, Y Kim, MW Steffes, TJ Groppoli, RJ Butkowski, SM Mauer
Kidney International 1994
Amelioration of diabetic nephropathy by treatment with monoclonal antibodies against glycated albumin
MP Cohen, E Hud, VY Wu
Kidney International 1994
Polyol pathway mediates high glucose-induced collagen synthesis in proximal tubule
AJ Bleyer, P Fumo, ER Snipes, S Goldfarb, DA Simmons, FN Ziyadeh
Kidney International 1994
High glucose elevates c-fos and c-jun transcripts and proteins in mesangial cell cultures
JI Kreisberg, RA Radnik, SH Ayo, JA Garoni, P Saikumar
Kidney International 1994
Renal TGF-β regulation in spontaneously diabetic NOD mice with correlations in mesangial cells
OG Pankewycz, JX Guan, WK Bolton, A Gomez, JF Benedict
Kidney International 1994
Diabetic nephropathy, renal hemodynamics, and aldose reductase inhibitors
PJ Oates
Drug Development Research 1994
High glucose and TGFβ1 stimulate fibronectin gene expression through a cAMP response element
JI Kreisberg, JA Garoni, R Radnik, SH Ayo
Kidney International 1994
Expression of transforming growth factor-β1 during diabetic renal hypertrophy
SJ Shankland, JW Scholey, H Ly, K Thai
Kidney International 1994
Estimating glomerular number in situ using magnetic resonance imaging and biopsy
JM Basgen, MW Steffes, AE Stillman, SM Mauer
Kidney International 1994
Immunohistochemical localization of collagen VI in diabetic glomeruli
AG Nerlich, ED Schleicher, I Wiest, U Specks, R Timpl
Kidney International 1994
Amadori glucose adducts modulate mesangial cell growth and collagen gene expression
MP Cohen, FN Ziyadeh
Kidney International 1994
Effects of different antihypertensive treatments on morphologic progression of diabetic nephropathy in uninephrectomized dogs
L Gaber, C Walton, S Brown, G Bakris
Kidney International 1994
CELLULAR AND MOLECULAR ABNORMALITIES IN THE VASCULAR ENDOTHELIUM OF DIABETES MELLITUS
GL King, T Shiba, J Oliver, T Inoguchi, SE Bursell
Annual Review of Medicine 1994
Microalbuminuria: Prognostic and Therapeutic Implications in Diabetes Mellitus
RE Gilbert, ME Cooper, PG McNally, RC O'Brien, J Taft, G Jerums
Diabetic Medicine 1994
Progression of glomerular diseases
EP Peten, LJ Striker
Journal of Internal Medicine 1994
The effect of an aldose reductase inhibitor (Epalrestat) on diabetic nephropathy in rats
I Itagaki, K Shimizu, Y Kamanaka, K Ebata, R Kikkawa, M Haneda, Y Shigeta
Diabetes Research and Clinical Practice 1994
A high concentration of glucose alters the production of tPA, uPA and PAI-1 antigens from human mesangial cells
H Tada, M Tsukamoto, H Ishii, S Isogai
Diabetes Research and Clinical Practice 1994
Extracellular Matrix Assembly and Structure
PD Yurchenco
Extracellular Matrix Assembly and Structure 1994
Glomerular metalloprotease activity in streptozotocin-treated rats and in spontaneously diabetic rats (BB/DP)
JF Reckelhoff, VL Tygart, LC Racusen, DJ Dzielak
Life Sciences 1994
Angiotensin-Converting Enzyme Inhibition Partially Prevents Diabetic Organomegaly
M Hajinazarian, FG Cosio, NS Nahman, JD Mahan, C McAllister
American Journal of Kidney Diseases 1994
Effect of Angiotensin Converting Enzyme Inhibitor on Collagen Production by Cultured Mesangial Cells
CG Ihm, JK Park, JH Ahn, TW Lee, MJ Kim
The Korean Journal of Internal Medicine 1994
Microalbuminuria: Pathogenesis, Prognosis and Management
BN Panayiotou
J INT MED RES 1994
Expression of glomerular extracellular matrix components in human diabetic nephropathy: decrease of heparan sulphate in the glomerular basement membrane
JT Tamsma, J van den Born, JA Bruijn, KJ Assmann, JJ Weening, JH Berden, J Wieslander, E Schrama, J Hermans, JH Veerkamp, HH Lemkes, FJ van der Woude
Diabetologia 1994
Glucose-induced protein kinase C activity regulates arachidonic acid release and eicosanoid production by cultured glomerular mesangial cells
B Williams, RW Schrier
Journal of Clinical Investigation 1993
Renal tubular basement membrane and collagen type IV in diabetes mellitus
FN Ziyadeh
Kidney International 1993
Alteration of mesangial response to ANP and angiotensin II by glucose
M Haneda, R Kikkawa, D Koya, T Uzu, S Maeda, M Togawa, Y Shigeta
Kidney International 1993
Determinants of end-stage renal disease in Pima Indians with Type 2 (non-insulin-dependent) diabetes mellitus and proteinuria
RG Nelson, WC Knowler, DR McCance, ML Sievers, DJ Pettitt, MA Charles, RL Hanson, QZ Liu, PH Bennett
Diabetologia 1993
Nonenzymatic glycation of mesangial matrix and prolonged exposure of mesangial matrix to elevated glucose reduces collagen synthesis and proteoglycan charge
S Silbiger, S Crowley, Z Shan, M Brownlee, J Satriano, D Schlondorff
Kidney International 1993
Long-term effects of antihypertensive regimens on renal hemodynamics and proteinuria
SA Brown, CL Walton, P Crawford, GL Bakris
Kidney International 1993
Ultrastructural study of glomerular basement membrane in diabetic rats by quick-freezing and deep-etching method
T Moriya, S Ohno, K Nakazawa, H Shigematsu, Y Yajima
Virchows Archiv B Cell Pathology Including Molecular Pathology 1993
Glomerular structure and function in proteinuric Type 2 (non-insulin-dependent) diabetic patients
R Østerby, MA Gall, A Schmitz, FS Nielsen, G Nyberg, HH Parving
Diabetologia 1993
Transforming growth factor beta increases the expression of HIV-1 gene in transfected human mesangial cells
RR Shukla, A Kumar, PL Kimmel
Kidney International 1993
The glomerular mesangium in diabetes mellitus
JI Kreisberg, SH Ayo
Kidney International 1993
Structural-functional relationships in type I mesangiocapillary glomerulonephritis
M Hattori, Y Kim, MW Steffes, SM Mauer
Kidney International 1993
Renal interstitial expansion in insulin-dependent diabetes mellitus
PH Lane, MW Steffes, P Fioretto, SM Mauer
Kidney International 1993
The kidney disease of diabetes mellitus (KDDM): A cell and molecular biology approach
GE Striker, EP Peten, CM Pesce, K Schmidt, CW Yang, SJ Elliot, LJ Striker, MA Carome
Diabetes / Metabolism Reviews 1993
The Effects of Angiotensin-Converting Enzyme Inhibitors on the Clinical and Biochemical Parameters in Diabetic Nephropathy
F Gültekin, GH Erdoĝan, U Özersoy, H Alagözlü
Renal Failure 1993
Effects of glycated albumin on mesangial cells: evidence for a role in diabetic nephropathy
FN Ziyadeh, MP Cohen
Molecular and Cellular Biochemistry 1993
Glucose-induced protein kinase C activity regulates arachidonic acid release and eicosanoid production by cultured glomerular mesangial cells
B Williams, RW Schrier
Life Sciences 1993
Glucose-induced protein kinase C activity regulates arachidonic acid release and eicosanoid production by cultured glomerular mesangial cells
B Williams, RW Schrier
Life Sciences 1993
Hyperglycemic glucose concentrations up-regulate the expression of type VI collagen in vitro. Relevance to alterations of peripheral nerves in diabetes mellitus
P Muona, S Jaakkola, RZ Zhang, TC Pan, L Pelliniemi, L Risteli, ML Chu, J Uitto, J Peltonen
The American Journal of Pathology 1993
Expression of transforming growth factor beta is elevated in human and experimental diabetic nephropathy
T Yamamoto, T Nakamura, NA Noble, E Ruoslahti, WA Border
Proceedings of the National Academy of Sciences 1993
Long-Term Complications of Diabetes Mellitus
DM Nathan
New England Journal of Medicine 1993
Type I diabetic nephropathy: Clinical characteristics and economic impact
C Chukwuma
Journal of Diabetes and its Complications 1993
Focal mesangiolysis and the pathogenesis of the Kimmelstiel-Wilson nodule
LC Stout, S Kumar, EB Whorton
Human Pathology 1993
Assessing the Effectiveness of Therapy to Prevent the Progression of Renal Disease
AS Levey
American Journal of Kidney Diseases 1993
Essential Hypertension in Blacks: Is It a Metabolic Disorder?
MR Weir, ML Tuck
American Journal of Kidney Diseases 1993
The Role of Macrophages in Diabetic Glomerulosclerosis
T Furuta, T Saito, T Ootaka, J Soma, K Obara, K Abe, K Yoshinaga
American Journal of Kidney Diseases 1993
The Extracellular Matrix in Diabetic Nephropathy
FN Ziyadeh
American Journal of Kidney Diseases 1993
Renal Disease in Adolescents With Type I Diabetes Mellitus: A Report of the Southwest Pediatric Nephrology Study Group
EN Ellis, TJ Pysher
American Journal of Kidney Diseases 1993
Diabetic nephropathy: What you need to know to preserve kidney function
GL Bakris
Postgraduate Medicine 1993
Widening of capillary neck and alteration of extracellular matrix ultrastructure in diabetic rat glomerulus as revealed by computer morphometry and improved tissue processing
I Shirato, T Sakai, M Fukui, Y Tomino, H Koide
Virchows Archiv A Pathological Anatomy and Histopathology 1993
ACE inhibitors and diabetic nephropathy: clinical and experimental findings
C Hasslacher, HP Kempe, A Bostedt-Kiesel
The Clinical Investigator 1993
Glomerular structure and function in proteinuric Type 2 (non-insulin-dependent) diabetic patients
R Østerby, , A Schmitz, FS Nielsen, G Nyberg,
Diabetologia 1993
Transforming growth factor-beta in disease: the dark side of tissue repair
WA Border, E Ruoslahti
Journal of Clinical Investigation 1992
Chronic blockade of nitric oxide synthesis in the rat produces systemic hypertension and glomerular damage
C Baylis, B Mitruka, A Deng
Journal of Clinical Investigation 1992
The kidney in non-insulin-dependent diabetes
A Schmitz
Acta Diabetologica 1992
Treatment of diabetes mellitus
RP Robertson, DJ Klein
Diabetologia 1992
Glomerular extracellular matrices in rat diabetic glomerulopathy by scanning electron microscopy
H Makino, Y Yamasaki, K Hironaka, Z Ota
Virchows Archiv B Cell Pathology Including Molecular Pathology 1992
Regulation of inositol transport by glucose and protein kinase C in mesangial cells
NJ Guzman, FT Crews
Kidney International 1992
Thromboxane in the pathogenesis of glomerular injury in diabetes
PA Craven, MF Melhem, FR DeRubertis
Kidney International 1992
High glucose-induced proliferation in mesangial cells is reversed by autocrine TGF-β
G Wolf, K Sharma, Y Chen, M Ericksen, FN Ziyadeh
Kidney International 1992
Correlation between MitochondriaI Enlargement in RenaI Proximal Tubules and Microalbuminuria in Rats with Early Streptozotocin-induced Diabetes
K Kaneda, J Iwao, N Sakata, S Takebayashi
Pathology International 1992
Mitochondrial Enlargement and Basement Membrane Thickening of Renal Proximal Tubules, Possible Initiators of Microalbuminuria in Non-Insulin-Dependent Diabetics (NIDDM)
K Kaneda, N Sakata, S Takebayashi
Pathology International 1992
Glomerular structural changes in Type 1 (insulin-dependent) diabetes mellitus: causes, consequences, and prevention
R �sterby
Diabetologia 1992
Changes in thickness and anionic sites of the glomerular basement membrane after subtotal nephrectomy in the rat
MP Dubrulle, F Terzi, MC Gubler, C Kleinknecht, M Schaeverbeke
The American Journal of Pathology 1992
Relation of Skin Capillary Pressure in Patients with Insulin-Dependent Diabetes Mellitus to Complications and Metabolic Control
DD Sandeman, AC Shore, JE Tooke
New England Journal of Medicine 1992
Interactions between hypertension and diabetes on vascular function and structure in rats
RG Tilton, G Pugliese, AM Faller, LS LaRose, MA Province, JR Williamson
Journal of Diabetes and its Complications 1992
Comments on the clinical impact of hypertension in type I diabetes
C Chukwuma
Journal of Diabetes and its Complications 1992
The kidney in non-insulin-dependent diabetes: Studies on glomerular structure and function and the relationship between microalbuminuria and mortality
A Schmitz
Acta Diabetologica 1992
Mesangial deposition of type I collagen in human glomerulosclerosis
AD Glick, HR Jacobson, MA Haralson
Human Pathology 1992
Tubular secretion of Tamm-Horsfall protein in type 1 (insulin-dependent) diabetes mellitus using a simplified enzyme linked immunoassay
O Torffvit, CD Agardh, B Kjellsson, J Wieslander
Clinica Chimica Acta 1992
In vivo interactions of TGF-β and extracellular matrix
NA Noble, JR Harper, WA Border
Progress in Growth Factor Research 1992
Uridine and cytidine nucleotide synthesis in renal hypertrophy: Biochemical differences in response to the growth stimulus of diabetes and unilateral nephrectomy
S Kunjara, M Sochor, M Ali, M Bennett, AL Greenbaum, P McLean
Biochemical Medicine and Metabolic Biology 1992
Diabetic Nephropathy in Insulin-Dependent Patients
JA Breyer
American Journal of Kidney Diseases 1992
Proteinuria, Hematuria, Hypertension, and Decreased Renal Function in a Patient With Diabetes for 9 Years
RA Rodby, MM Schwartz
American Journal of Kidney Diseases 1992
Diabetic Glomerulosclerosis and Chronic Renal Failure With Absent-to-Minimal Microalbuminuria
DJ Steele, RG Yeron, C Abendroth, JR Diamond
American Journal of Kidney Diseases 1992
An Overview of Renal Pathology in Insulin-Dependent Diabetes Mellitus in Relationship to Altered Glomerular Hemodynamics
P Fioretto, MW Steffes, DM Brown, SM Mauer
American Journal of Kidney Diseases 1992
Glomerular size-selectivity and microalbuminuria in early diabetic glomerular disease
JD Scandling, BD Myers
Kidney International 1992
Modulation of glomerular proteoglycans by insulin-like growth factor-1
Y Watanabe, N Kashihara, H Makino, YS Kanwar
Kidney International 1992
Relationship of systemic blood pressure to nephropathology in insulin-dependent diabetes mellitus
SM Mauer, DE Sutherland, MW Steffes
Kidney International 1992
Glomerular structure in type-1 (insulin-dependent) diabetic patients with normo- and microalbuminuria
JD Walker, CF Close, SL Jones, M Rafftery, H Keen, GC Viberti, R Østerby
Kidney International 1992
Elevated glucose stimulates TGF-β gene expression and bioactivity in proximal tubule
MV Rocco, Y Chen, S Goldfarb, FN Ziyadeh
Kidney International 1992
Effects of high glucose on cellular proliferation and fibronectin production by cultured human mesangial cells
NS Nahman, KL Leonhart, FG Cosio, CL Hebert
Kidney International 1992
Production of extracellular matrix by glomerular epithelial cells is regulated by transforming growth factor-β1
T Nakamura, D Miller, E Ruoslahti, WA Border
Kidney International 1992
Antagonists of transforming growth factor-β: A novel approach to treatment of glomerulonephritis and prevention of glomerulosclerosis
WA Border, NA Noble, T Yamamoto, S Tomooka, S Kagami
Kidney International 1992
Heparan sulfate proteoglycan in the glomerular basement membrane in type 1 diabetes mellitus
RL Vernier, MW Steffes, S Sisson-Ross, SM Mauer
Kidney International 1992
An electron microscopic study of glomeruli in Japanese patients with non-insulin dependent diabetes mellitus
H Hayashi, R Karasawa, H Inn, T Saitou, M Ueno, S Nishi, Y Suzuki, S Ogino, Y Maruyama, Y Kouda, M Arakawa
Kidney International 1992
International Yearbook of Nephrology 1993
VE Andreucci, LG Fine
1992
Hyperglycemia, Diabetes, and Vascular Disease
N Ruderman, J Williamson, M Brownlee
1992
Clearance rate of immunoglobulins and diabetic nephropathy
UD Mario, R Romano, S Morano, P Pietravalle
Acta Diabetologica 1992
Indices of renal structure and function in patients with type 1 diabetes mellitus
MW Steffes, P Fioretto, SM Mauer
Acta Diabetologica 1992
Mechanisms of glucose-induced extracellular matrix overproduction by cultured vascular cells
F Pricci, G Pugliese, F Pugliese, P Men, D Andreani, G Galli, A Casini, CM Rotella, U di Mario
Acta Diabetologica 1992
Diabetes and Atherosclerosis
RW Stout
1992
The Management of Diabetic Proteinuria: Which Antihypertensive Agent?
ME Cooper, AE Doyle
Drugs & Aging 1992
Glomerular structural changes in Type 1 (insulin-dependent) diabetes mellitus: causes, consequences, and prevention
R sterby
Diabetologia 1992
Glomerular function in Pima Indians with noninsulin-dependent diabetes mellitus of recent onset
BD Myers, RG Nelson, GW Williams, PH Bennett, SA Hardy, RL Berg, N Loon, WC Knowler, WE Mitch
Journal of Clinical Investigation 1991
Glucose-induced metabolic imbalances in the pathogenesis of diabetic vascular disease
G Pugliese, RG Tilton, JR Williamson
Diabetes / Metabolism Reviews 1991
The renal tubulointerstitium in diabetes mellitus
FN Ziyadeh, S Goldfarb
Kidney International 1991
Functional and structural alterations of the glomerular permeability barrier in experimental galactosemia
BS Daniels, TH Hostetter, SM Kren
Kidney International 1991
A new computer-assisted three-dimensional reconstruction method provides accurate measurement of glomerular mesangial volume
CR Cho, J Winslow, C Whiteside, CJ Lumsden
Journal of Electron Microscopy Technique 1991
Global glomerular sclerosis and glomerular arteriolar hyalinosis in insulin dependent diabetes
RD Harris, MW Steffes, RW Bilous, DE Sutherland, SM Mauer
Kidney International 1991
Diabetic Nephropathy: New Directions in Management
MD Sirmonw, WG Kirkpatrick
Renal Failure 1991
Differential expression of basement membrane collagen chains in diabetic nephropathy
Y Kim, MM Kleppel, R Butkowski, SM Mauer, J Wieslander, AF Michael
The American Journal of Pathology 1991
Dietary protein restriction rapidly reduces transforming growth factor beta 1 expression in experimental glomerulonephritis
S Okuda, T Nakamura, T Yamamoto, E Ruoslahti, WA Border
Proceedings of the National Academy of Sciences 1991
Human and rat mesangial cell receptors for glucose-modified proteins: potential role in kidney tissue remodelling and diabetic nephropathy
EY Skolnik, Z Yang, Z Makita, S Radoff, M Kirstein, H Vlassara
Journal of Experimental Medicine 1991
Enlarging Our View of the Diabetic Kidney
SL Gluck, S Klahr
New England Journal of Medicine 1991
The Pathogenesis of Chronic Renal Failure in Diabetic Nephropathy
A Bohle, M Wehrmann, O Bogenschütz, C Batz, GA Müller, GA Müller
Pathology - Research and Practice 1991
International Review of Cytology
RA Miller
International Review of Cytology 1991
Mesangial cell dysfunction
R Kikkawa, M Haneda, D Koya, Y Shigeta
Journal of Diabetic Complications 1991
Morphologic study of the kidney in Japanese non-insulin-dependent patients
Y Suzuki, M Ueno, H Hayashi, S Nishi, R Karasawa, H Inn, H Satou, S Suzuki, Y Maruyama, Y Ninomiya, M Arakawa
Journal of Diabetic Complications 1991
Glucose-induced overproduction of type IV collagen in cultured glomerular mesangial cells
M Haneda, R Kikkawa, N Horide, M Togawa, D Koya, N Kajiwara, S Maeda, Y Shigeta
Journal of Diabetic Complications 1991
Structural-functional relationships in type I insulin-dependent diabetes mellitus in humans
P Lane, MW Steffes, SM Mauer
Journal of Diabetic Complications 1991
Discordant effects of the aldose resuctase inhibitor, sorbinil, on vascular structure and function in chronically diabetic and galactosemic rats
RG Tilton, G Pugliese, LS LaRose, AM Faller, K Chang, MA Province, JR Williamson
Journal of Diabetic Complications 1991
Prevention of glomerular basement membrane thickening by aminoguanidine in experimental diabetes mellitus
EN Ellis, BH Good
Metabolism 1991
Hypertension as a Causative Diagnosis of Patients Entering End-Stage Renal Disease Programs in the United States From 1980 to 1986
WB Blythe, FW Maddux
American Journal of Kidney Diseases 1991
Benign Pleural Effusions in Long-Standing Diabetes Mellitus
BS Chertow, R Kadzielawa, AJ Burger
Chest 1991
Diabetic Nephropathy: Changing Concepts of Pathogenesis and Treatment
DS Bell
The American Journal of the Medical Sciences 1991
Nephrology
M Hatano
Nephrology 1991
Kidney transplantation in Type 1 (insulin-dependent) diabetic patients: Early glomerulopathy
R sterby, G Nyberg, L Hedman, I Karlberg, H Persson, C Svalander
Diabetologia 1991
Renal insulin-like growth factor I and growth hormone receptor binding in experimental diabetes and after unilateral nephrectomy in the rat
SM Marshall, A Flyvbjerg, J Frystyk, L Korsgaard, H rskov
Diabetologia 1991
The effect of aldose reductase inhibitors on glomerular prostaglandin production and urinary albumin excretion in experimental diabetes mellitus
WP Chang, E Dimitriadis, T Allen, ME Dunlop, M Cooper, RG Larkins
Diabetologia 1991
Glucose enhances type IV collagen production in cultured rat glomerular mesangial cells
M Haneda, R Kikkawa, N Horide, M Togawa, D Koya, N Kajiwara, A Ooshima, Y Shigeta
Diabetologia 1991
The role of the pediatric nephrologist in the care of children with diabetes mellitus
P Lane, M Steffes, SM Mauer
Pediatric Nephrology 1991
Efficacy of captopril in postponing nephropathy in normotensive insulin dependent diabetic patients with microalbuminuria
ER Mathiesen, E Hommel, J Giese, HH Parving
BMJ : British Medical Journal 1991
Prevention in nephrology
ME de Broe, GA Verpooten
1991
Organ Transplantation 1990
GM Abouna, MS Kumar, AG White
1991
Glomerular hypertrophy aggravates epithelial cell injury in nephrotic rats
PL Miller, JW Scholey, HG Rennke, TW Meyer
Journal of Clinical Investigation 1990
Is glomerulosclerosis a consequence of altered glomerular permeability to macromolecules?
G Remuzzi, T Bertani
Kidney International 1990
Renal biopsy
MP Madaio
Kidney International 1990
Transforming growth factor-β regulates production of proteoglycans by mesangial cells
WA Border, S Okuda, LR Languino, E Ruoslahti
Kidney International 1990
A Clinical-histological Study of Individuals with Diabetes Mellitus and Proteinuria
JL Taft, VR Billson, A Nankervis, P Kincaid-Smith, FI Martin
Diabetic Medicine 1990
High glucose causes an increase in extracellular matrix proteins in cultured mesangial cells
SH Ayo, RA Radnik, JA Garoni, WF 2nd, JI Kreisberg
The American Journal of Pathology 1990
Glucose inhibits myo-inositol uptake and reduces myo-inositol content in cultured rat glomerular mesangial cells
M Haneda, R Kikkawa, T Arimura, K Ebata, M Togawa, S Maeda, T Sawada, N Horide, Y Shigeta
Metabolism 1990
Urinary excretion of the carboxy terminal domain of type IV collagen is associated with kidney size and function in IDDM
O Torffvit, J Wieslander, L Forsberg, E Hederström, CD Agardh
Journal of Diabetic Complications 1990
Should There Be an Expanded Role for Kidney Biopsy in the Management of Patients With Type I Diabetes?
SM Mauer, BM Chavers, MW Steffes
American Journal of Kidney Diseases 1990
The effect of exercise on urinary excretion of different size proteins in patients with insulin-dependent diabetes mellitus
L Groop, S Stenman, PH Groop, A Makipernaa, AM Teppo
Scandinavian Journal of Clinical & Laboratory Investigation 1990
Renal Disease in Noninsulin-Dependent Diabetes Mellitus
MD Sirmon
The American Journal of the Medical Sciences 1990
Suppression of experimental glomerulonephritis by antiserum against transforming growth factor β1
WA Border, S Okuda, LR Languino, MB Sporn, E Ruoslahti
Nature 1990
Renal Complications in Non-insulin-dependent Diabetes Mellitus
LL Humphrey, DJ Ballard
Clinics in Geriatric Medicine 1990
Immunogold studies of monomeric elements from the globular domain (NC1) of type IV collagen in renal basement membranes during experimental diabetes in the rat
M Desjardins, F Gros, J Wieslander, MC Gubler, M Bendayan
Diabetologia 1990
International Yearbook of Nephrology 1990
VE Andreucci, LG Fine, CM Kjellstrand, N Sugino
1990
Effects of fish oil on glomerular function in rats with diabetes mellitus
AK Sinha, LA Scharschmidt, R Neuwirth, H Holthofer, N Gibbons, CM Arbeeny, D Schlondorff
Journal of lipid research 1990
Transforming growth factor-beta. Murine glomerular receptors and responses of isolated glomerular cells
K MacKay, LJ Striker, JW Stauffer, T Doi, LY Agodoa, GE Striker
Journal of Clinical Investigation 1989
Effects of dietary protein content in streptozotocin-diabetic rats
SM Mauer, MW Steffes, S Azar, DM Brown
Kidney International 1989
Can management strategies alter the course of diabetic nephropathy?
AL Drash, DJ Becker
The Indian Journal of Pediatrics 1989
Effects of very mild versus overt diabetes on vascular haemodynamics and barrier function in rats
G Pugliese, RG Tilton, A Speedy, K Chang, E Santarelli, MA Province, D Eades, WR Sherman, JR Williamson
Diabetologia 1989
Reduced Urinary Excretion of Epidermal Growth Factor in Incipient and Overt Diabetic Nephropathy
ER Mathiesen, E Nexø, E Hommel, HH Parving
Diabetic Medicine 1989
Why do some diabetics never develop vasculopathic complications?
BR Boshell, M Austria
Journal of Diabetic Complications 1989
Effect of a low protein diet on the relationship of nonenzymatic glycation to altered renal structure and function in diabetes mellitus
KR Copeland, RW Yatscoff, JA Thliveris, SB Penner, A Mehta
Journal of Diabetic Complications 1989
Diabetic nephropathy in insulin-dependent diabetic patients: Renal hemodynamics and derived treatment strategies
PM Wee, AJ Donker
Journal of Diabetic Complications 1989
The long-term effect of pancreatic islet allotransplantation on glomerular basement membrane thickening in experimental diabetes
J Brown, AA Sima, WJ Tze, J Tai, JA Thliveris
Journal of Diabetic Complications 1989
Glomerular Lesions and Urinary Albumin Excretion in Type I Diabetes without Overt Proteinuria
BM Chavers, RW Bilous, EN Ellis, MW Steffes, SM Mauer
New England Journal of Medicine 1989
The Effects of Pancreas Transplantation on the Glomerular Structure of Renal Allografts in Patients with Insulin-Dependent Diabetes
RW Bilous, SM Mauer, DE Sutherland, JS Najarian, FC Goetz, MW Steffes
New England Journal of Medicine 1989
Aldose reductase in the etiology of diabetic complications: 2. Nephropathy
D Stribling, FM Armstrong, HE Harrison
Journal of Diabetic Complications 1989
Angiotensin-Converting Enzyme Inhibitors in the Prevention of Experimental Diabetic Glomerulopathy
BD Myers, TW Meyer
American Journal of Kidney Diseases 1989
Albuminuria reflects widespread vascular damage: The Steno hypothesis
T Deckert, B Feldt-Rasmussen, K Borch-Johnsen, T Jensen, A Kofoed-Enevoldsen
Diabetologia 1989
Diabetic nephropathy: Etiology and prevention
GC Viberti, JD Walker
Diabetes / Metabolism Reviews 1988
Pathogenesis of diabetic glomerulopathy: Hemodynamic considerations
S Anderson, BM Brenner
Diabetes / Metabolism Reviews 1988
Ultrafiltration coefficients of glomeruli from human biopsies
WP Richardson, R Hassanein, RV Pinnick, VJ Savin
Kidney International 1988
Distinguishing minimal-change disease from mesangial disorders
WA Border
Kidney International 1988
Basement membrane abnormalities in diabetes mellitus: Relationship to clinical microangiopathy
JR Williamson, RG Tilton, K Chang, C Kilo
Diabetes / Metabolism Reviews 1988
Prognostic implications of renal hypertrophy in diabetes mellitus
KS Kleinman, LG Fine
Diabetes / Metabolism Reviews 1988
Advanced products of nonenzymatic glycosylation and the pathogenesis of diabetic vascular disease
M Brownlee, A Cerami, H Vlassara
Diabetes / Metabolism Reviews 1988
PANCREAS TRANSPLANTATION FOR DIABETES
DE Sutherland, FC Goetz, JS Najarian, JR Salaman
The Lancet 1988
Ultrastructural investigation of renal biopsies: A discussion of artifacts and special methodology
TS Olsen, LC Racusen, K Solez
Journal of Electron Microscopy Technique 1988
Renal vascular disease in diabetes mellitus
AR Morley
Histopathology 1988
Nephropathy in non-insulin-dependent diabetes mellitus
P Tung, SR Levin
The American Journal of Medicine 1988
Effects of nephrectomy and high-protein diets on glomerular hemodynamics and urinary protein excretion in diabetic rats
RG Tilton, G Pugliese, K Chang, C Kilo, JR Williamson
Journal of Diabetic Complications 1988
Reduced urinary kallikrein in hypertensive diabetic patients
M Marre, F Alhenc-Gelas, J Menard, P Passa
Journal of Diabetic Complications 1988
Some lessons from the studies of renal biopsies in patients with insulin-dependent diabetes mellitus
SM Mauer, RW Bilous, E Ellis, R Harris, MW Steffes
Journal of Diabetic Complications 1988
Receptors for and effects of insulin and IGF-I in rat glomerular mesangial cells
HJ Arnqvist, BJ Ballermann, GL King
American journal of physiology. Cell physiology 1988
Doença de Chagas aguda pós-transfusional sem miocardite
EP de Campos, I Maestá, FC de Schmidt, R Sogayar, CE de Campos
Revista da Sociedade Brasileira de Medicina Tropical 1988
Hypertension in Diabetes Mellitus
J Rosenstock, P Raskin
Cardiology Clinics 1988
Prevention of diabetic nephropathy with enalapril in normotensive diabetics with microalbuminuria
M Marre, G Chatellier, H Leblanc, TT Guyene, J Menard, P Passa
BMJ : British Medical Journal 1988
A strong correlation between glomerular filtration rate and filtration surface in diabetic nephropathy
R Osterby, H H Parving, G Nyberg, E Hommel, H E Jørgensen, H Løkkegaard, C Svalander
Diabetologia 1988
Increased glucose increases glomerular basement membrane in metanephric culture
J Bernstein, F Cheng, J Roszka
Pediatric Nephrology 1987
Non-enzymatic glycation and altered renal structure and function in the diabetic rat
KR Copeland, RW Yatscoff, JA Thliveris, A Mehta, B Penner
Kidney International 1987
Estimation of mean glomerular volume in patients with insulin-dependent diabetes mellitus
RW Bilous, SM Mauer, JM Basgen, MW Steffes
Kidney International 1987
Observations of glomerular epithelial cell structure in patients with type I diabetes mellitus
EN Ellis, MW Steffes, B Chavers, SM Mauer
Kidney International 1987
Microalbuminuria as a predictor of clinical diabetic nephropathy
CE Mogensen
Kidney International 1987
Evidence against increased glomerular pressure initiating diabetic nephropathy
N Bank, R Klose, HS Aynedjian, D Nguyen, LB Sablay
Kidney International 1987
Lack of effect of gliclazide on early diabetic nephropathy and retinopathy: a two-year controlled study
G Jerums, RM Murray, E Seeman, ME Cooper, S Edgley, K Marwick, RG Larkins, TJ Martin
Diabetes Research and Clinical Practice 1987
Systemic hypertension, diabetes mellitus and the kidney
AR Christlieb, AS Krolewski, JH Warram
The American Journal of Cardiology 1987
New vessel formation in the renal corpuscles in advanced diabetic glomerulopathy
R Østerby, G Nyberg
Journal of Diabetic Complications 1987
Case 14-1987: A 73-Year-Old Woman with Proteinuria and Coronary-Artery Disease
RC Cabot, RE Scully, EJ Mark, WF McNeely, BU McNeely
New England Journal of Medicine 1987
Home Blood Glucose Monitoring: Keystone for Modern Diabetes Care
AL McCall, CJ Mullin
Medical Clinics of North America 1987
Raised arterial pressure in parents of proteinuric insulin dependent diabetics
GC Viberti, H Keen, MJ Wiseman
BMJ : British Medical Journal 1987
Progress in Surgery of the Liver, Pancreas and Biliary System
S Bengmark
1987
Effects of indomethacin on kidney function in type 1 (insulin-dependent) diabetic patients with nephropathy
E Hommel, E Mathiesen, S Arnold-Larsen, B Edsberg, U B Olsen, H H Parving
Diabetologia 1987
Nature of the glomerular capillary injury in human membranous glomerulopathy
O Shemesh, JC Ross, WM Deen, GW Grant, BD Myers
Journal of Clinical Investigation 1986
Acute reduction of arterial blood pressure reduces urinary albumin excretion in Type 1 (insulin-dependent) diabetic patients with incipient nephropathy
E Hommel, E Mathiesen, B Edsberg, M Bahnsen, HH Parving
Diabetologia 1986
Glomerular filtration surface in type I diabetes mellitus
EN Ellis, MW Steffes, FC Goetz, DE Sutherland, SM Mauer
Kidney International 1986
Pancreatic Transplantation
G Tydén, CG Groth
International Journal of Technology Assessment in Health Care 1986
Blind Alleys in Diabetes Research
TL Dornan, RB Tattersall
Diabetic Medicine 1986
The pathogenesis and prevention of diabetic glomerulopathy
BD Myers
The Western journal of medicine 1986
The pathogenesis and prevention of diabetic nephropathy
R Omachi
The Western journal of medicine 1986
New therapies for the chronic complications of older diabetic patients
RS Clements
The American Journal of Medicine 1986
The kidney in diabetes: Significance of the early abnormalities
GC Viberti, MJ Wiseman
Clinics in Endocrinology and Metabolism 1986
Structural changes in the diabetic kidney
R Østerby
Clinics in Endocrinology and Metabolism 1986
Diabetes mellitus in the child and adolescent: Part II
AL Drash
Current Problems in Pediatrics 1986
Home Monitoring of Diabetes Mellitus—A Quiet Revolution
AL McCall, CJ Mullin
Clinics in Laboratory Medicine 1986
Increased transcapillary escape rate of albumin in Type 1 (insulin-dependent) diabetic patients with microalbuminuria
B Feldt-Rasmussen
Diabetologia 1986
Quantitative glomerular morphology of the normal and diabetic baboon kidney
LC Stout, DS Folse, J Meier, WM Crosby, R Kling, GR Williams, WE Price, JR Geyer, R Padula, E Whorton, P Kimmelstiel
Diabetologia 1986
Acute reduction of arterial blood pressure reduces urinary albumin excretion in Type 1 (insulin-dependent) diabetic patients with incipient nephropathy
E Hommel, E Mathiesen, B Edsberg, M Bahnsen,
Diabetologia 1986
Effects of mesangial localization of polyvinyl alcohols on glomerular basement membrane thickness
SM Mauer, MW Steffes, DM Brown
Kidney International 1985
Studies of Kidney and Muscle Biopsy Specimens from Identical Twins Discordant for Type I Diabetes Mellitus
MW Steffes, DE Sutherland, FC Goetz, SS Rich, SM Mauer
New England Journal of Medicine 1985
Relationship of renal size to nephropathy in Type 1 (insulin-dependent) diabetes
EN Ellis, MW Steffes, FC Goetz, DE Sutherland, SM Mauer
Diabetologia 1985
Blood pressure changes and renal function in incipient and overt diabetic nephropathy
CE Mogensen, CK Christensen
Hypertension 1985
Comparison of Type I and Type II Diabetes
M Vranic, CH Hollenberg, G Steiner
1985
Do genetic factors play a role in the pathogenesis of diabetic microangiopathy?
J Barbosa, B Saner
Diabetologia 1984
Diabetic microangiopathy in KK mice
AS Reddi, W Oppermann, M Chen, RA Camerini-Davalos
Experimental and Molecular Pathology 1978

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ISSN: 0021-9738 (print), 1558-8238 (online)

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