We studied the production of and response to interleukin-2 (IL-2) by peripheral blood T lymphocytes from 19 systemic lupus erythematosus (SLE) patients who received no treatment at the time they were studied. Eight had active disease and the rest were in remission. Results were compared with those obtained in 12 healthy subjects of similar age. T cells from SLE patients, whether activated with phytohemagglutinin or in autologous mixed lymphocyte reactions, were found to yield little IL-2, to have a low response to IL-2 from its own, or other sources, and to absorb IL-2 poorly, IL-2 produced by SLE cells, albeit scant, was absorbed normally by activated T cells from normal subjects. Our findings may contribute to the understanding of the immunoregulatory defect in SLE.
J Alcocer-Varela, D Alarcón-Segovia
Year: | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 | 2013 | 2012 | 2011 | 2010 | 2009 | 2008 | 2007 | 2006 | 2005 | 2004 | 2003 | 2002 | 2001 | 2000 | 1999 | 1998 | 1997 | 1996 | 1995 | 1994 | 1993 | 1992 | 1991 | 1990 | 1989 | 1988 | 1987 | 1986 | 1985 | 1984 | 1983 | 1960 | Total |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Citations: | 2 | 2 | 2 | 6 | 3 | 2 | 1 | 5 | 5 | 3 | 6 | 8 | 3 | 5 | 10 | 8 | 5 | 10 | 3 | 5 | 4 | 6 | 7 | 5 | 5 | 5 | 10 | 6 | 5 | 3 | 6 | 10 | 8 | 9 | 16 | 16 | 23 | 21 | 14 | 23 | 23 | 19 | 12 | 1 | 351 |
Title and authors | Publication | Year |
---|---|---|
IL-2 detected by flow cytometry and its significance in systemic lupus erythematosus.
Li Y, Wang T, Gan Y, Zhang X, Xue L, Xu B, Sun X, Li Z |
Clinical rheumatology | 2025 |
Immunometabolism in systemic lupus erythematosus.
Patiño-Martinez E, Kaplan MJ |
Nature reviews. Rheumatology | 2025 |
Hypothetical proteins of chicken-isolated Limosilactobacillus reuteri subjected to in silico analyses induce IL-2 and IL-10
Adejumo IO |
Genes & Nutrition | 2024 |
Roles of TULA-family proteins in T cells and autoimmune diseases.
Wang H, Concannon P, Ge Y |
Genes and immunity | 2024 |
UBASH3A Interacts with PTPN22 to Regulate IL2 Expression and Risk for Type 1 Diabetes
Newman JR, Concannon P, Ge Y |
International journal of molecular sciences | 2023 |
Endosome Traffic Modulates Pro-Inflammatory Signal Transduction in CD4+ T Cells—Implications for the Pathogenesis of Systemic Lupus Erythematosus
Park JS, Perl A |
International journal of molecular sciences | 2023 |
The deacetylase SIRT2 contributes to autoimmune disease pathogenesis by modulating IL-17A and IL-2 transcription
R Hisada, N Yoshida, M Umeda, C Burbano, R Bhargava, M Scherlinger, M Kono, V Kyttaris, S Krishfield, G Tsokos |
Cellular and Molecular Immunology | 2022 |
T Cells, Interleukin-2 and Systemic Lupus Erythematosus—From Pathophysiology to Therapy
Mak A |
Cells | 2022 |
Pathogenic T-Cell Responses in Immune-Mediated Glomerulonephritis
Linke A, Tiegs G, Neumann K |
Cells | 2022 |
Jak Inhibitors for Treatment of Autoimmune Diseases: Lessons from Systemic Sclerosis and Systemic Lupus Erythematosus
Kotyla P, Gumkowska-Sroka O, Wnuk B, Kotyla K |
Pharmaceuticals | 2022 |
Increased sIL-2Rα leads to obstruction of IL-2 biological function and Treg cells differentiation in SLE patients via binding to IL-2.
Long D, Yu S, Zhang L, Guo Y, Xu S, Rao Y, Huang Z, Luo Q, Li J |
Frontiers in immunology | 2022 |
Vitamin D Presented In Vitro Immunomodulatory Property on T Lymphocyte-Related Cytokines in Systemic Lupus Erythematosus.
Mariz HA, Sato EI, Cardoso PRG, Gonçalves R, Duarte ALBP, de Melo Rego MJB, da Rocha Pitta I, da Rocha Pitta MG |
Inflammation | 2022 |
Immune regulation in renal inflammation
K Neumann, G Tiegs |
Cell and Tissue Research | 2021 |
Interleukin-2 and regulatory T cells in rheumatic diseases
AG Kolios, GC Tsokos, D Klatzmann |
Nature Reviews Rheumatology | 2021 |
Disease presentation and surgical treatment of patients with foreign-body granulomas and ASIA syndrome: case series
J Lopez-Mendoza, E Vargas-Flores, N Mouneu-Ornelas, C Altamirano-Arcos |
Archives of Plastic Surgery | 2021 |
The Surprising Story of IL-2
AK Abbas |
The American Journal of Pathology | 2020 |
B7-H3: A promising therapeutic target for autoimmune diseases
Y Chen, SY Guan, J Deng, H Yang, W Xu, S Xu, M Shao, X Gao, S Xu, Z Shuai, F Pan |
Cellular Immunology | 2020 |
The 2017 Incentive Award of the Okayama Medical Association in General Medical Science (2017 Yuuki Prize)
E Katsuyama |
Okayama Igakkai Zasshi (Journal of Okayama Medical Association) | 2019 |
The Involvement of MicroRNAs in Modulation of Innate and Adaptive Immunity in Systemic Lupus Erythematosus and Lupus Nephritis
M Honarpisheh, P Köhler, E von Rauchhaupt, M Lech |
Journal of Immunology Research | 2018 |
Aberrant T Cell Signaling and Subsets in Systemic Lupus Erythematosus
T Katsuyama, GC Tsokos, VR Moulton |
Frontiers in immunology | 2018 |
Prophylactic and Therapeutic Effects of Interleukin-2 (IL-2)/Anti-IL-2 Complexes in Systemic Lupus Erythematosus-Like Chronic Graft-Versus-Host Disease
S Heiler, J Lötscher, M Kreuzaler, J Rolink, A Rolink |
Frontiers in immunology | 2018 |
Caffeine inhibits STAT1 signaling and downregulates inflammatory pathways involved in autoimmunity
M Iris, PS Tsou, AH Sawalha |
Clinical Immunology | 2018 |
Revisiting IL-2: Biology and therapeutic prospects
AK Abbas, E Trotta, DR Simeonov, A Marson, JA Bluestone |
Science Immunology | 2018 |
Patients with Systemic Lupus Erythematosus Show Increased Levels and Defective Function of CD69 + T Regulatory Cells
M Vitales-Noyola, B Oceguera-Maldonado, P Niño-Moreno, N Baltazar-Benítez, L Baranda, E Layseca-Espinosa, C Abud-Mendoza, R González-Amaro |
Mediators of Inflammation | 2017 |
Downregulation of miR-200a-3p, Targeting CtBP2 Complex, Is Involved in the Hypoproduction of IL-2 in Systemic Lupus Erythematosus–Derived T Cells
E Katsuyama, M Yan, KS Watanabe, S Matsushima, Y Yamamura, S Hiramatsu, K Ohashi, H Watanabe, T Katsuyama, S Zeggar, N Yoshida, VR Moulton, GC Tsokos, KE Sada, J Wada |
Journal of immunology (Baltimore, Md. : 1950) | 2017 |
Aiolos Overexpression in Systemic Lupus Erythematosus B Cell Subtypes and BAFF-Induced Memory B Cell Differentiation Are Reduced by CC-220 Modulation of Cereblon Activity
Y Nakayama, J Kosek, L Capone, EM Hur, PH Schafer, GE Ringheim |
Journal of immunology (Baltimore, Md. : 1950) | 2017 |
Lupus
WA Khan |
Lupus | 2017 |
Patients with Systemic Lupus Erythematosus Show Increased Levels and Defective Function of CD69 + T Regulatory Cells
M Vitales-Noyola, B Oceguera-Maldonado, P Niño-Moreno, N Baltazar-Benítez, L Baranda, E Layseca-Espinosa, C Abud-Mendoza, R González-Amaro |
Mediators of Inflammation | 2017 |
Regulatorische T‑Zellen beim systemischen Lupus erythematodes: IL-2 entscheidend für Verlust der Toleranz
K Ohl, K Tenbrock |
Zeitschrift für Rheumatologie | 2016 |
The Role of the Transcription Factor Ets1 in Lupus and Other Autoimmune Diseases
LA Garrett-Sinha, A Kearly, AB Satterthwaite |
Critical reviews in immunology | 2016 |
Association of interleukin-2 and interferon-γ single nucleotide polymorphisms with Juvenile systemic lupus erythematosus
S Harsini, V Ziaee, F Tahghighi, M Mahmoudi, A Rezaei, S Soltani, M Sadr, MH Moradinejad, Y Aghighi, N Rezaei |
Allergologia et Immunopathologia | 2016 |
Low-dose interleukin-2 selectively corrects regulatory T cell defects in patients with systemic lupus erythematosus
C Spee-Mayer, E Siegert, D Abdirama, A Rose, A Klaus, T Alexander, P Enghard, B Sawitzki, F Hiepe, A Radbruch, GR Burmester, G Riemekasten, JY Humrich |
Annals of the rheumatic diseases | 2015 |
T cells as a therapeutic target in SLE
D Comte, MP Karampetsou, GC Tsokos |
Lupus | 2015 |
Interleukin-2 treatment reverses effects of cAMP-responsive element modulator α -over-expressing T cells in autoimmune-prone mice: The CREM/IL-2 axis drives autoimmunity
K Ohl, A Wiener, A Schippers, N Wagner, K Tenbrock |
Clinical & Experimental Immunology | 2015 |
miRNAs in the Pathogenesis of Systemic Lupus Erythematosus
B Qu, N Shen |
International journal of molecular sciences | 2015 |
Epigenetic Aspects of Systemic Lupus Erythematosus
M Relle, B Foehr, A Schwarting |
Rheumatology and Therapy | 2015 |
Epigenetic Aspects of Systemic Lupus Erythematosus
M Relle, B Foehr, A Schwarting |
Rheumatology and Therapy | 2015 |
MicroRNA Regulation in Systemic Lupus Erythematosus Pathogenesis
S Yan, LY Yim, L Lu, CS Lau, VS Chan |
Immune Network | 2014 |
The Pathology of T Cells in Systemic Lupus Erythematosus
A Mak, NY Kow |
Journal of Immunology Research | 2014 |
Regulatory T cells in systemic lupus erythematosus: Highlights
K Ohl, K Tenbrock |
European Journal of Immunology | 2014 |
Relationship between Serum Level of Interleukin-2 in Patients with Systemic Lupus Erythematosus and Disease Activity in Comparison with Control Group
S Sedighi, M Aghaei, S Musavi, M Nomali |
Journal of Clinical and Diagnostic Research : JCDR | 2014 |
Emerging role of IL-17 and Th17 cells in systemic lupus erythematosus
JC Martin, DL Baeten, R Josien |
Clinical Immunology | 2014 |
The role of T cells in systemic lupus erythematosus: an update
C Konya, Z Paz, GC Tsokos |
Current Opinion in Rheumatology | 2014 |
T cell receptor-associated protein tyrosine kinases: The dynamics of tolerance regulation by phosphorylation and its role in systemic lupus erythematosus
A Barrera-Vargas, D Gómez-Martín, J Alcocer-Varela |
Human Immunology | 2014 |
Risk Factors for Drug-resistant Bloodstream Infections in Patients with Systemic Lupus Erythematosus
A Barrera-Vargas, D Gómez-Martín, J Merayo-Chalico, A Ponce-de-León, J Alcocer-Varela |
The Journal of rheumatology | 2014 |
Dubois' Lupus Erythematosus and Related Syndromes
JC Crispín, GC Tsokos |
Dubois' Lupus Erythematosus and Related Syndromes | 2013 |
Casitas B Lineage Lymphoma b Is a Key Regulator of Peripheral Tolerance in Systemic Lupus Erythematosus
D Gómez-Martín, M Ibarra-Sánchez, J Romo-Tena, J Cruz-Ruíz, J Esparza-López, M Galindo-Campos, M Díaz-Zamudio, J Alcocer-Varela |
Arthritis & Rheumatism | 2013 |
Systemic Lupus Erythematosus and Psoriasis: Comparison of Immunopathogenesis
M Perl, C Wolinsky |
Psoriasis forum / National Psoriasis Foundation | 2013 |
Calcium/calmodulin-dependent protein kinase IV suppresses IL-2 production and regulatory T cell activity in lupus
T Koga, K Ichinose, M Mizui, JC Crispín, GC Tsokos |
Journal of immunology (Baltimore, Md. : 1950) | 2012 |
CD4+CD25+ regulatory T cells from MRL/lpr mice were functionally more active in vitro but did not prevent spontaneous as well as adriamycin-induced nephropathy in vivo
HR Kim, JH Kie, W Lim, BI Moon, SC Kim, JY Seoh |
Rheumatology | 2012 |
Alterations in T-lymphocyte sub-set profiles and cytokine secretion by PBMC of systemic lupus erythematosus patients upon <i>in vitro</i> exposure to organochlorine pesticides
SA Dar, S Das, VG Ramachandran, SN Bhattacharya, MD Mustafa, BD Banerjee, P Verma |
Journal of Immunotoxicology | 2012 |
Alterations in T-lymphocyte sub-set profiles and cytokine secretion by PBMC of systemic lupus erythematosus patients upon in vitro exposure to organochlorine pesticides
SA Dar, S Das, VG Ramachandran, SN Bhattacharya, MD Mustafa, BD Banerjee, P Verma |
Journal of Immunotoxicology | 2012 |
IL-17: A new actor in IFN-driven systemic autoimmune diseases: HIGHLIGHTS
A Ambrosi, A Espinosa, M Wahren-Herlenius |
European Journal of Immunology | 2012 |
Resistance to Exogenous TGF-β Effects in Patients with Systemic Lupus Erythematosus
A Elbeldi-Ferchiou, MB Ahmed, M Smiti-Khanfir, MH Houman, M Abdeladhim, NB Hmida, N Cerf-Bensussan, H Louzir |
Journal of Clinical Immunology | 2011 |
cAMP-responsive element modulator (CREM)α protein signaling mediates epigenetic remodeling of the human interleukin-2 gene: implications in systemic lupus erythematosus
CM Hedrich, T Rauen, GC Tsokos |
The Journal of biological chemistry | 2011 |
Quantitative and functional profiles of CD4+ lymphocyte subsets in systemic lupus erythematosus patients with lymphopenia
D Gómez-Martín, M Díaz-Zamudio, G Vanoye, JC Crispín, J Alcocer-Varela |
Clinical & Experimental Immunology | 2011 |
The Dysregulation of Cytokine Networks in Systemic Lupus Erythematosus
SA Apostolidis, LA Lieberman, K Kis-Toth, JC Crispín, GC Tsokos |
Journal of Interferon & Cytokine Research | 2011 |
Inflammatory Cytokines in Systemic Lupus Erythematosus
K Ohl, K Tenbrock |
Journal of Biomedicine and Biotechnology | 2011 |
Quantitative and functional profiles of CD4+ lymphocyte subsets in systemic lupus erythematosus patients with lymphopenia
D Gómez-Martín, M Díaz-Zamudio, G Vanoye, JC Crispín, J Alcocer-Varela |
Clinical & Experimental Immunology | 2011 |
Advances in Immunology
E Pinaud, M Marquet, R Fiancette, S Péron, C Vincent-Fabert, Y Denizot, M Cogné |
Advances in Immunology Volume 110 | 2011 |
Annual Reports in Medicinal Chemistry
JJ Liu, TW Lee |
Annual Reports in Medicinal Chemistry Volume 46 | 2011 |
T-Cells and Systemic Lupus Erythematosus
JC Crispín, GC Tsokos |
Systemic Lupus Erythematosus | 2011 |
TH17 Cells in Health and Disease
S Jiang |
2011 | |
T cells as therapeutic targets in SLE
JC Crispín, VC Kyttaris, C Terhorst, GC Tsokos |
Nature Reviews Rheumatology | 2010 |
The IL-2 Defect in Systemic Lupus Erythematosus Disease Has an Expansive Effect on Host Immunity
LA Lieberman, GC Tsokos |
Journal of Biomedicine and Biotechnology | 2010 |
Interferon-alpha regulates the dynamic balance between human activated regulatory and effector T cells: implications for antiviral and autoimmune responses
A Golding, A Rosen, M Petri, E Akhter, F Andrade |
Immunology | 2010 |
Defectivein vitroIL-2 production in lupus is an early but secondary event paralleling disease activity: Evidence from the murine parent-into-F1 model supports staging of IL-2 defects in human lupus
CS Via, GM Shearer |
Autoimmunity | 2010 |
Serum Levels and in Vitro Production of Th1- and Th2-Type Cytokines by Peripheral Blood Mononuclear Cells in Patients Suffering from Systemic Lupus Erythematosus
VB Đorđević, L Zvezdanović, V Ćosić, P Vlahović, S Kundalić, T Jevtović-Stoimenov, B Stamenković, DR Mitrović |
Journal of Medical Biochemistry | 2010 |
mTOR signaling: a central pathway to pathogenesis in systemic lupus erythematosus?
D Fernandez, A Perl |
Discovery medicine | 2010 |
Defective in vitro IL-2 production in lupus is an early but secondary event paralleling disease activity: Evidence from the murine parent-into-F1 model supports staging of IL-2 defects in human lupus
CS Via, GM Shearer |
Autoimmunity | 2010 |
IL-17 in Systemic Lupus Erythematosus
JC Crispín, GC Tsokos |
Journal of Biomedicine and Biotechnology | 2010 |
Pulmonary surfactant: an immunological perspective
ZC Chroneos, Z Sever-Chroneos, VL Shepherd |
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology | 2009 |
Interleukin 2 and systemic lupus erythematosus
D Gómez-Martín, M Díaz-Zamudio, JC Crispín, J Alcocer-Varela |
Autoimmunity Reviews | 2009 |
Studies of cell-mediated immune responses to influenza vaccination in systemic lupus erythematosus
A Holvast, S Assen, A Haan, A Huckriede, CA Benne, J Westra, A Palache, J Wilschut, CG Kallenberg, M Bijl |
Arthritis & Rheumatism | 2009 |
Cytokines in systemic lupus erythematosus
EV Lourenço, AL Cava |
Current molecular medicine | 2009 |
Lupus and T Cells
AL Cava |
Lupus | 2009 |
Novel molecular targets in the treatment of systemic lupus erythematosus
JC Crispín, GC Tsokos |
Autoimmunity Reviews | 2008 |
Dehydroepiandrosterone in systemic lupus erythematosus
AH Sawalha, S Kovats |
Current Rheumatology Reports | 2008 |
G/T polymorphism in the interleukin-2 exon 1 region among Han Chinese systemic lupus erythematosus patients in Taiwan
YJ Lin, L Wan, JJ Sheu, CM Huang, CW Lin, YC Lan, CH Lai, CH Hung, Y Tsai, CH Tsai, WY Lin, HP Liu, TH Lin, YM Huang, FJ Tsai |
Clinical Immunology | 2008 |
Modulation of the IL-2 production defect in vitro in Graves’disease
Z Eisenstein, E Engelsman, M Weiss, Y Kalechman, B Sredni |
Clinical & Experimental Immunology | 2008 |
B7/BB1 provides an important costimulatory signal for CD3-mediated T lymphocyte proliferation in patients with systemic lupus erythematosus (SLE)
PP Sfikakis, R Oglesby, P Sfikakis, GC Tsokos |
Clinical & Experimental Immunology | 2008 |
Cytokine-independent progression of immunoglobulin production in vitro by B lymphocytes from patients with systemic lupus erythematosus
BK Pelton, M Speckmaier, W Hylton, J Farrant, AM Denman |
Clinical & Experimental Immunology | 2008 |
The effect of the immunomodulator agent AS101 on interleukin-2 production in systemic lupus erythematosus (SLE) induced in mice by a pathogenic anti-DNA antibody
M Blank, B Sredni, M Albeck, E Mozes, Y Shoenfeld |
Clinical & Experimental Immunology | 2008 |
Soluble interleukin-2 receptor, interleukin-2 and interleukin-4 in sera and supernatants from patients with progressive systemic sclerosis
G Famularo, A Procopio, R Giacomelli, C Danese, S Sacchetti, MA Perego, A Santoni, G Tonietti |
Clinical & Experimental Immunology | 2008 |
Function of CD4+,CD25+ Treg cells in MRL/lpr mice is compromised by intrinsic defects in antigen-presenting cells and effector T cells
V Parietti, F Monneaux, M Décossas, S Muller |
Arthritis & Rheumatism | 2008 |
Expanded Double Negative T Cells in Patients with Systemic Lupus Erythematosus Produce IL-17 and Infiltrate the Kidneys
JC Crispín, M Oukka, G Bayliss, RA Cohen, CA Beek, IE Stillman, VC Kyttaris, YT Juang, GC Tsokos |
Journal of immunology (Baltimore, Md. : 1950) | 2008 |
Systemic lupus erythematosus: new molecular targets
JC Crispín, V Kyttaris, YT Juang, GC Tsokos |
Annals of the rheumatic diseases | 2007 |
Lipid rafts in T cell signalling and disease
EC Jury, F Flores-Borja, PS Kabouridis |
Seminars in Cell & Developmental Biology | 2007 |
Agrin Signalling Contributes to Cell Activation and Is Overexpressed in T Lymphocytes from Lupus Patients
EC Jury, J Eldridge, DA Isenberg, PS Kabouridis |
Journal of immunology (Baltimore, Md. : 1950) | 2007 |
The genetics of systemic lupus erythematosus: understanding how SNPs confer disease susceptibility
ME Alarcón-Riquelme |
Springer Seminars in Immunopathology | 2006 |
Monoclonal anti-double-stranded DNA antibodies cross-react with phosphoglycerate kinase 1 and inhibit the expression and production of IL-2 in activated Jurkat T cell line
HY Luan, SJ Tang, W Yang, CY Tsai, GH Sun, KH Sun |
Clinical Immunology | 2006 |
Genetic control of the spontaneous activation of CD4+ Th cells in systemic lupus erythematosus-prone (NZB × NZW) F1 mice
T Fujii, Y Iida, M Yomogida, K Ikeda, T Haga, Y Jikumaru, M Ninami, N Nishimura, Y Kodera, Y Inada, T Shirai, S Hirose, H Nishimura |
Genes and Immunity | 2006 |
Regulatory T cells in patients with systemic lupus erythematosus
B Alvarado-Sánchez, B Hernández-Castro, D Portales-Pérez, L Baranda, E Layseca-Espinosa, C Abud-Mendoza, AC Cubillas-Tejeda, R González-Amaro |
Journal of Autoimmunity | 2006 |
Systemic Lupus Erythematosus
M Petri |
JCR: Journal of Clinical Rheumatology | 2006 |
Altered regulation of IL-2 production in systemic lupus erythematosus: an evolving paradigm
GM Kammer |
Journal of Clinical Investigation | 2005 |
Autoimmune mechanisms in children with systemic lupus erythematosus
D Stichweh, V Pascual |
Current Rheumatology Reports | 2005 |
Cytokine profiles of skin lesions in murine lupus models
T Nishide, T Yoshimasu, T Ikeda, N Seo, T Ohtani, F Furukawa |
Journal of Dermatological Science Supplement | 2005 |
IL-15 and IL-15R in leucocytes from patients with systemic lupus erythematosus
L Baranda, H la Fuente, E Layseca-Espinosa, D Portales-Pérez, P Niño-Moreno, G Valencia-Pacheco, C Abud-Mendoza, J Alcocer-Varela, R González-Amaro |
Rheumatology (Oxford, England) | 2005 |
Effects of prasterone on disease activity and symptoms in women with active systemic lupus erythematosus
MA Petri, PJ Mease, JT Merrill, RG Lahita, MJ Iannini, DE Yocum, EM Ginzler, RS Katz, OS Gluck, MC Genovese, RV Vollenhoven, KC Kalunian, S Manzi, MW Greenwald, JP Buyon, NJ Olsen, MH Schiff, AF Kavanaugh, JR Caldwell, R Ramsey-Goldman, EW st. Clair, AL Goldman, RM Egan, RP Polisson, KG Moder, NF Rothfield, RT Spencer, K Hobbs, BJ Fessler, LH Calabrese, LW Moreland, SB Cohen, BJ Quarles, V Strand, M Gurwith, KE Schwartz |
Arthritis & Rheumatism | 2004 |
TRANSCRIPTIONAL REGULATION OF INTERLEKIN 2 IN SLE T CELLS
K Tenbrock, GC Tsokos |
International Reviews of Immunology | 2004 |
Effects of prasterone on disease activity and symptoms in women with active systemic lupus erythematosus: Results of a multicenter randomized, double-blind, placebo-controlled trial
MA Petri, PJ Mease, JT Merrill, RG Lahita, MJ Iannini, DE Yocum, EM Ginzler, RS Katz, OS Gluck, MC Genovese, RV Vollenhoven, KC Kalunian, S Manzi, MW Greenwald, JP Buyon, NJ Olsen, MH Schiff, AF Kavanaugh, JR Caldwell, R Ramsey-Goldman, EW st. Clair, AL Goldman, RM Egan, RP Polisson, KG Moder, NF Rothfield, RT Spencer, K Hobbs, BJ Fessler, LH Calabrese, LW Moreland, SB Cohen, BJ Quarles, V Strand, M Gurwith, KE Schwartz |
Arthritis & Rheumatism | 2004 |
Biomarkers in systemic lupus erythematosus: II. Markers of disease activity
GG Illei, E Tackey, L Lapteva, PE Lipsky |
Arthritis & Rheumatism | 2004 |
Down-Regulation of IL-2 Production in T Lymphocytes by Phosphorylated Protein Kinase A-RIIβ
MR Elliott, RA Shanks, IU Khan, JW Brooks, PJ Burkett, BJ Nelson, V Kyttaris, YT Juang, GC Tsokos, GM Kammer |
Journal of immunology (Baltimore, Md. : 1950) | 2004 |
CD4 + and CD8 + Regulatory T Cells Generated Ex Vivo with IL-2 and TGF-β Suppress a Stimulatory Graft-versus-Host Disease with a Lupus-Like Syndrome
SG Zheng, JH Wang, MN Koss, F Quismorio, JD Gray, DA Horwitz |
Journal of immunology (Baltimore, Md. : 1950) | 2004 |
Defective activity of ERK-1 and ERK-2 mitogen-activated protein kinases in peripheral blood T lymphocytes from patients with systemic lupus erythematosus: potential role of altered coupling of Ras guanine nucleotide exchange factor hSos to adapter protein Grb2 in lupus T cells☆☆Supported by Grant S1-200000440 from Fondo Nacional de Ciencia, Innovación y Tecnologia (FONACIT), Ministerio de Ciencia y Tecnologia
S Cedeño, DF Cifarelli, AM Blasini, M Paris, F Placeres, G Alonso, MA Rodriguez |
Clinical Immunology | 2003 |
Pathogenesis of systemic lupus erythematosus
CC Mok, CS Lau |
Journal of clinical pathology | 2003 |
Immunobiologic consequences of assist devices
S Itescu, M Schuster, E Burke, J Ankersmit, A Kocher, M Deng, R John, K Lietz |
Cardiology Clinics | 2003 |
Immunopathology and the gene therapy of lupus
RA Mageed, GJ Prud'homme |
Gene Therapy | 2003 |
Immunoregulatory defects in patients with systemic lupus erythematosus in clinical remission
JC Crispin, J Alcocer-Varela, P Pablo, A Martínez, Y Richaud-Patin, D Alarcón-Segovia |
Lupus | 2003 |
Cytokines and Chemokines in Autoimmune Disease
P Santamaria |
2003 | |
T Cell Rewiring in Differentiation and Disease
S Krishnan, DL Farber, GC Tsokos |
Journal of immunology (Baltimore, Md. : 1950) | 2003 |
Dehydroepiandrosterone for the treatment of systemic lupus erythematosus
RF van Vollenhoven |
Expert Opinion on Pharmacotherapy | 2002 |
Autoimmunity, dehydroepiandrosterone (DHEA), and stress
KE Schwartz |
Journal of Adolescent Health | 2002 |
Abnormal T cell signal transduction in systemic lupus erythematosus
GM Kammer, A Perl, BC Richardson, GC Tsokos |
Arthritis & Rheumatism | 2002 |
Serum C4 levels in patients with systemic lupus erythematosus in remission
M Yasuda, Y Suenaga, H Nishimukai, M Nobunaga |
Modern Rheumatology | 2002 |
Effects of prasterone on corticosteroid requirements of women with systemic lupus erythematosus: A double-blind, randomized, placebo-controlled trial
MA Petri, RG Lahita, RF van Vollenhoven, JT Merrill, M Schiff, EM Ginzler, V Strand, A Kunz, KJ Gorelick, KE Schwartz |
Arthritis & Rheumatism | 2002 |
Receptor polymorphisms and diseases
A Császár, T Ábel |
European Journal of Pharmacology | 2001 |
Trichostatin A reverses skewed expression of CD154, interleukin-10, and interferon-gamma gene and protein expression in lupus T cells
N Mishra, DR Brown, IM Olorenshaw, GM Kammer |
Proceedings of the National Academy of Sciences | 2001 |
Molecular basis of deficient IL-2 production in T cells from patients with systemic lupus erythematosus
EE Solomou, YT Juang, MF Gourley, GM Kammer, GC Tsokos |
Journal of immunology (Baltimore, Md. : 1950) | 2001 |
Serum interleukin‐15 is elevated in systemic lupus erythematosus
M Aringer, GH Stummvoll, G Steiner, M Köller, CW Steiner, E Höfler, H Hiesberger, JS Smolen, WB Graninger |
Rheumatology (Oxford, England) | 2001 |
T Cell Studies in a Peptide-Induced Model of Systemic Lupus Erythematosus
M Khalil, K Inaba, R Steinman, J Ravetch, B Diamond |
Journal of immunology (Baltimore, Md. : 1950) | 2001 |
DEHYDROEPIANDROSTERONE IN SYSTEMIC LUPUS ERYTHEMATOSUS
RF van Vollenhoven |
Rheumatic Disease Clinics of North America | 2000 |
Immunobiology of left ventricular assist devices
S Itescu, JH Ankersmit, AA Kocher, MD Schuster |
Progress in Cardiovascular Diseases | 2000 |
Rôle des cytokines dans la physiopathologie du lupus
JF Viallard, JL Taupin, V Ranchin, B Leng, JL Pellegrin, JF Moreau |
Immuno-analyse & Biologie Spécialisée | 2000 |
INACTIVE SYSTEMIC LUPUS ERYTHEMATOSUS IS ASSOCIATED WITH A NORMAL STIMULATED TH1/TH2CYTOKINE SECRETORY PATTERN
M Amit, A Mor, J Weissgarten, R Rosenberg, Y Ramot, AJ Wysenbeek, MJ Rapoport |
Cytokine | 2000 |
Association of Deficient Type II Protein Kinase A Activity with Aberrant Nuclear Translocation of the RIIβ Subunit in Systemic Lupus Erythematosus T Lymphocytes
N Mishra, IU Khan, GC Tsokos, GM Kammer |
Journal of immunology (Baltimore, Md. : 1950) | 2000 |
New Pieces to the SLE Cytokine Puzzle
KA Kirou, MK Crow |
Clinical Immunology | 1999 |
Th1 (IL-2, interferon-gamma (IFN-gamma)) and Th2 (IL-10, IL-4) cytokine production by peripheral blood mononuclear cells (PBMC) from patients with systemic lupus erythematosus (SLE)
JF Viallard, JL Pellegrin, V Ranchin, T Schaeverbeke, J Dehais, M Longy-Boursier, JM Ragnaud, B Leng, JF Moreau |
Clinical & Experimental Immunology | 1999 |
Role of NK cells and TGF-β in the regulation of T-cell-dependent antibody production in health and autoimmune disease
DA Horwitz, JD Gray, K Ohtsuka |
Microbes and Infection | 1999 |
High prevalence of T cell type I protein kinase a deficiency in systemic lupus erythematosus
GM Kammer |
Arthritis & Rheumatism | 1999 |
Integrin signalling defects in T-lymphocytes in systemic lupus erythematosus
TT Ng, IE Collins, SB Kanner, MJ Humphries, N Amft, RG Wickremasinghe, D D'Cruz, KE Nye, WJ Morrow |
Lupus | 1999 |
A double-blind, placebo-controlled, clinical trial of dehydroepiandrosterone in severe systemic lupus erythematosus
RF van Vollenhoven, JL Park, MC Genovese, JP West, JL McGuire |
Lupus | 1999 |
High disease activity at baseline does not prevent a remission in patients with systemic lupus erythematosus
F Formiga, I Moga, M Pac, F Mitjavila, A Rivera, R Pujol |
Rheumatology (Oxford, England) | 1999 |
Polymorphisms within the interleukin-10 receptor cDNA gene (IL10R) in Japanese patients with systemic lupus erythematosus
H Nakashima, M Akahoshi, Y Tanaka, K Yamaoka, E Ogami, S Nagano, Y Arinobu, H Niiro, T Otsuka, Y Niho |
Rheumatology (Oxford, England) | 1999 |
Induction of anti-thymocyte/T lymphocyte antibodies in mice injected with lipopolysaccharides from periodontopathic bacteria
T Kaneko, Y Hara, A Yoshimura, I Kato |
Journal of Periodontal Research | 1999 |
Quantitative Changes In T-Cell Populations After Left Ventricular Assist Device Implantation: Relationship to T-Cell Apoptosis and Soluble CD95
HJ Ankersmit, NM Edwards, M Schuster, R John, A Kocher, EA Rose, M Oz, S Itescu |
Circulation | 1999 |
Altered pattern of TCR/CD3-mediated protein-tyrosyl phosphorylation in T cells from patients with systemic lupus erythematosus. Deficient expression of the T cell receptor zeta chain
SN Liossis, XZ Ding, GJ Dennis, GC Tsokos |
Journal of Clinical Investigation | 1998 |
Relations between surface expression of the interleukin-2 receptor and release of the soluble form of the receptor in cultured mononuclear cells from patients with rheumatoid arthritis or systemic lupus erythematosus
M Itoh, Y Goto, Y Ohta, Y Goto, H Ohashi |
Clinical Rheumatology | 1998 |
Immune cell signaling aberrations in human lupus
SN Liossis, PP Sfikakis, GC Tsokos |
Immunologic Research | 1998 |
Decreased Th1-like and Increased Th2-like Cells in Systemic Lupus Erythematosus
MF H |
Scandinavian Journal of Rheumatology | 1998 |
Interleukin-2 and systemic lupus erythematosus—fifteen years later
JC Crispin, J Alcocer-Varela |
Lupus | 1998 |
Cytokines: clues to the pathogenesis of SLE
BR Lauwerys, FA Houssiau |
Lupus | 1998 |
Studies of T cell receptors in autoimmune diseases
K Yamamoto |
Japanese Journal of Rheumatology | 1997 |
New methods of treatment in an experimental murine model of systemic lupus erythematosus induced by idiotypic manipulation
Y Shoenfeld, I Krause, M Blank |
Annals of the rheumatic diseases | 1997 |
Dysregulation of interleukin-10 production in relatives of patients with systemic lupus erythematosus
L Llorente, Y Richaud-Patin, J Couderc, D Alarcon-Segovia, R Ruiz-Soto, N Alcocer-Castillejos, J Alcocer-Varela, J Granados, S Bahena, P Galanaud, D Emilie |
Arthritis & Rheumatism | 1997 |
Abnormalities in CD69 expression, cytosolic pH and Ca2+ during activation of lymphocytes from patients with systemic lupus erythematosus
D Portales-Pérez, R González-Amaro, C Abud-Mendoza, S Sánchez-Armáss |
Lupus | 1997 |
Systemic lupus erythematosus associated with transverse myelitis and Parkinsonian symptoms
H Osawa, H Yamabe, M Kaizuka, N Tamura, S Tsunoda, KI Shirato, K Okumura |
Lupus | 1997 |
Remission of Systemic Lupus Erythematosus
C Drenkard, AR Villa, C Garcia-Padilla, ME Perez-Vazquez, D Alarcon-Segovia |
Medicine | 1996 |
Remission of Systemic Lupus Erythematosus:
C Drenkard, AR Villa, C Garcia-Padilla, ME Perez-Vazquez, D Alarcon-Segovia |
Medicine | 1996 |
Expression of IL-2R, IL-4R, IL-6R on peripheral blood lymphocytes in systemic lupus erythematosus and correlation with disease activity: a prospective study
EY Chan, CS Lau, H Zola |
Journal of clinical pathology | 1996 |
Abnormal Splenic and Thymic IL-4 and TNF-alpha Expression in MRL-lpr/lpr Mice
CY Tsai, TH Wu, SF Huang, KH Sun, SC Hsieh, SH Han, HS Yu, CL Yu |
Scandinavian Journal of Immunology | 1995 |
Cytokine production in drug-free and neuroleptic-treated schizophrenic patients
H Bessler, Z Levental, L Karp, I Modai, M Djaldetti, A Weizman |
Biological Psychiatry | 1995 |
Immunopathogenesis and Therapy of Systemic Lupus Erythematosus
L Kater, FH Gmelig-Meyling, RH Derksen, HB Faille |
Clinical immunotherapeutics | 1995 |
Production of interferons and lymphokines in leukocyte cultures of patients with schizophrenia
M Hornberg, V Arolt, I Wilke, A Kruse, H Kirchner |
Schizophrenia Research | 1995 |
Longitudinal study on the production of and cellular response to interleukin-2 in patients with systemic lupus erythematocus
J Alcocer-Varela, D Alarcn-Segovia |
Rheumatology International | 1995 |
Demonstration of interleukin-2, interleukin-4 and interleukin-6 in sera from patients with localized scleroderma
H Ihn, S Sato, M Fujimoto, K Kikuchi, K Takehara |
Archives of Dermatological Research | 1995 |
Imbalance of the interleukin 2 system in children with IDDM
T Tomoda, T Kurashige, T Taniguchi |
Diabetologia | 1994 |
Cytokines and systemic sclerosis
DM Fagundus, EC Leroy |
Clinics in Dermatology | 1994 |
Modulation of the IL-2 production defect in vitro in Graves' disease
Z Eisenstein, E Engelsman, M Weiss, Y Kalechman, B Sredni |
Clinical & Experimental Immunology | 1994 |
An open study of dehydroepiandrosterone in systemic lupus erythematosus
RF van Vollenhoven, EG Engleman, JL Mcguire |
Arthritis & Rheumatism | 1994 |
Cytokine Gene Profile in Circulating Blood Mononuclear Cells from Patients with Systemic Lupus Erythematosus: Increased Interleukin-2 but not Interleukin-4 mRNA
DA Horwitz, H Wang, JD Gray |
Lupus | 1994 |
Immunology of the Connective Tissue Diseases
GS Panayi |
1994 | |
T helper cell dysfunction in systemic lupus erythematosus (SLE): Relation to disease activity
BL Bermas, M Petri, D Goldman, B Mittleman, MW Miller, NI Stocks, CS Via, GM Shearer |
Journal of Clinical Immunology | 1994 |
The cytokine network in the pathogenesis of systemic lupus erythematosus and possible therapeutic implications
DA Horwitz, CO Jacob |
Springer Seminars in Immunopathology | 1994 |
The role of cytokines in the immunopathogenesis of lupus
BS Handwerger, V Rus, L da Silva, CS Via |
Springer Seminars in Immunopathology | 1994 |
B7/BB1 provides an important costimulatory signal for CD3-mediated T lymphocyte proliferation in patients with systemic lupus erythematosus (SLE).
Sfikakis PP, Oglesby R, Sfikakis P, Tsokos GC |
Clinical & Experimental Immunology | 1994 |
T- and B-Cell Abnormalities in Systemic Lupus
PL Cohen |
Journal of Investigative Dermatology | 1993 |
Interleukin-1 dysregulation is an intrinsic defect in macrophages from MRL autoimmune-prone mice
JS Levine, BJ Pugh, D Hartwell, JM Fitzpatrick, A Marshak-Rothstein, DI Beller |
European Journal of Immunology | 1993 |
Immunologic significance of increased soluble CD8/CD4 molecules in patients with active systemic lupus erythematosus
S Sawada, H Hashimoto, S Iijima, Y Tokano, M Takei, M Shida, T Obara |
Journal of Clinical Laboratory Analysis | 1993 |
Elevated serum soluble interleukin-2 receptor levels in subacute cutaneous lupus erythematosus
C Neish, M Charley, N Fertig, T Medsger, JS Deng |
Journal of Dermatological Science | 1993 |
Lithium In Vitro Enhances Interleukin-2 Production by T Cells from Patients with Systemic Lupus Erythematosus
EJ Kucharz, SJ Sierakowski, JS Goodwin |
Immunopharmacology and Immunotoxicology | 1993 |
Relationship of IL-2, IL-2R (CD25 + ), Soluble IL-2R and IL-4 with Disease Activity in SLE Patients
MJ Cuadrado, M Marubayashi, C Ortega, N Fernandez-Arcas, F Garcia-Cozar, J Pena, P Sanchez-Guijo, M Santamaria |
Lupus | 1993 |
Relationship of IL-2, IL-2R (CD25+), Soluble IL-2R and IL-4 with Disease Activity in SLE Patients
MJ Cuadrado, M Marubayashi, C Ortega, N Fernandez-Arcas, F Garcia-Cozar, J Pena, P Sanchez-Guijo, M Santamaria |
Lupus | 1993 |
Circulating intercellular adhesion molecule 1 as a new activity marker in patients with systemic lupus erythematosus
E Kling, S Bieg, M Boehme, WA Scherbaum |
The Clinical Investigator | 1993 |
Administration of interleukin-2 induces major histocompatibility complex class II expression on the biliary epithelial cells, possibly through endogenous interferon-γ production
H Himeno, T Saibara, S Onishi, Y Yamamoto, H Enzan |
Hepatology | 1992 |
Altered interleukin-2 production in schizophrenia: Association between clinical state and autoantibody production
R Ganguli, JS Brar, W Solomon, KN Chengappa, BS Rabin |
Psychiatry Research | 1992 |
Decreased mitogen responsiveness and elevated tumor necrosis factor production in cats shortly after feline immunodeficiency virus infection
CE Lawrence, JJ Callanan, O Jarrett |
Veterinary Immunology and Immunopathology | 1992 |
Enhanced expression of high-affinity interleukin-2 receptors in scleroderma: Possible role for IL-6
MB Kahaleh, T Yin |
Clinical Immunology and Immunopathology | 1992 |
Low dose stretozotocin-induced diabetes in mice: Reduced IL-2 production and modulation of streptozotocin-induced hyperglycemia by IL-2
V Burkart, J Zielasek, G Kantwerk-Funke, T Hibbe, E Schwab, H Kolb |
International Journal of Immunopharmacology | 1992 |
Cytokine abnormalities in human lupus
M Linker-Israeli |
Clinical Immunology and Immunopathology | 1992 |
Production of Interleukin-2 IL-2 and Expression of IL-2 Receptor in Patients with IgA Nephropathy
TW Lee, MJ Kim |
The Korean Journal of Internal Medicine | 1992 |
Interleukin-1 and Interleukin-6 Activities are Increased in the Cerebrospinal Fluid of Patients with CNS Lupus Erythematosus and Correlate with Local Late T-Cell Activation Markers
J Alcocer-Varela, D Aleman-Hoey, D Alarcon-Segovia |
Lupus | 1992 |
A long-term immunological study of childhood onset systemic lupus erythematosus
CK Ting, KH Hsieh |
Annals of the rheumatic diseases | 1992 |
Functional T cell subpopulations responsible for hyposecretion of IL-2 in patients with systemic lupus erythematosus
T Hayama, N Kubo, E Ikeda, H Hashimoto, S Sawada, T Horie |
Clinical Rheumatology | 1991 |
Systemic lupus erythematosus: RNA-protein autoantigens, models of disease heterogeneity, and theories of etiology
JB Harley, RH Scofield |
Journal of Clinical Immunology | 1991 |
Studies of CD4+ (Helper/Inducer) T Lymphocytes in Autoimmune Thyroid Disease: Demonstration of Specific Induction in Response to Thyroid Peroxidase (TPO) In Vitro and Its Relationship with Thyroid Status In Vivo
F Akasu, Y Kasuga, S Matsubayashi, P Carayon, R Volpé |
Thyroid | 1991 |
Activation markers on peripheral blood T cells from patients with active or inactive systemic lupus erythematosus. Correlation with proliferative responses and production of IL-2
J Alcocer-Varela, M Alarcón-Riquelme, A Laffón, F Sánchez-Madrid, D Alarcón-Segovia |
Journal of Autoimmunity | 1991 |
Prolactin, immunoregulation, and autoimmune diseases
LJ Jara, C Lavalle, A Fraga, C Gómez-Sanchez, LH Silveira, P Martinez-Osuna, BF Germain, LR Espinoza |
Seminars in Arthritis and Rheumatism | 1991 |
In vitro mitogen responses and lymphocyte subpopulations in cheetahs
M Miller-Edge, M Worley |
Veterinary Immunology and Immunopathology | 1991 |
In vitro regulation of B cell differentiation by interleukin-6 and soluble CD23 in systemic lupus erythematosus B cell subpopulations and antigen-induced normal B cells
DJ Klashman, RA Martin, RH Stevens, O Martínez-Maza |
Arthritis & Rheumatism | 1991 |
Enhanced CD3-mediated T lymphocyte proliferation in patients with systemic lupus erythematosus
IL Stekman, AM Blasini, M Leon-Ponte, ML Baroja, I Abadi, MA Rodriguez |
Arthritis & Rheumatism | 1991 |
Defective CD2 pathway T cell activation in systemic lupus erythematosus
DA Fox, JA Millard, J Treisman, W Zeldes, A Bergman, J Depper, R Dunne, WJ McCune |
Arthritis & Rheumatism | 1991 |
A defect in the protein kinase C system in T cells from patients with systemic lupus erythematosus
Y Tada, K Nagasawa, Y Yamauchi, H Tsukamoto, Y Niho |
Clinical Immunology and Immunopathology | 1991 |
Soluble immunologic products in scleroderma sera
MB Kahaleh |
Clinical Immunology and Immunopathology | 1991 |
Human CD8+ lymphocytes stimulated in the absence of CD4+ cells enhance IgG production by antibody-secreting B cells
T Takahashi, JD Gray, DA Horwitz |
Clinical Immunology and Immunopathology | 1991 |
Gangliosides Inhibit the Proliferation of Human T Cells Stimulated with Interleukin-4 or Interleukin-2
N Morioka, M Furue, T Tsuchida, Y Ishibashi |
The Journal of Dermatology | 1991 |
Loss of interleukin-2—Producing intestinal CD4+ T cells in inflammatory bowel disease
K Kusugami, T Matsuura, GA West, KR Youngman, D Rachmilewitz, C Fiocchi |
Gastroenterology | 1991 |
Interleukin 2 production in a family with systemic lupus erythematosus and a C4Q0 heterozygous inheritance
C Gutierrez, E Cabrero, JL Vicario, MM Villa, MA Rengel, FJ Campdera, M Yebra, E Fernandez-Cruz, AA Villena |
Annals of the rheumatic diseases | 1991 |
Cytokine-independent progression of immunoglobulin production in vitro by B lymphocytes from patients with systemic lupus erythematosus.
Pelton BK, Speckmaier M, Hylton W, Farrant J, Denman AM |
Clinical & Experimental Immunology | 1991 |
Effect of colchicine on lymphocyte and monocyte function and its relation to fibroblast proliferation in primary biliary cirrhosis
D Kershenobich, M Rojkind, A Quiroga, J Alcocer-Varela |
Hepatology | 1990 |
Increased Circulating HLA-DR+CD4+ T Cells in Systemic Lupus Erythematosus: Alterations Associated with Prednisolone Therapy
S Raziuddin, MA Nur, AA Al-Wabel |
Scandinavian Journal of Immunology | 1990 |
Soluble Interleukin-2 Receptor Secretion Defectin Vitroin HLA-B8, DR3 Positive Subjects
MA Modica, GD Lorenzo, A Galluzzo, C Giordano, MR Portelli, G Candore, C Caruso |
Autoimmunity | 1990 |
Cytokines in the Pathophysiology of Systemic Lupus Erythematosus
M Goldman |
Autoimmunity | 1990 |
Antibodies to Interleukin 2 in Sera of Autoimmune-prone Mice
M Tabata, K Kobayashi, S Kaga, M Hashimoto, T Kasama, T Fukushima, K Yoshida, N Yamagata, F Sekine, I Ohno, M Negishi, H Ide, T Takahashi |
Scandinavian Journal of Rheumatology | 1990 |
Inhibition of lymphoproliferation and protein kinase C by synthetic peptides with sequence identity to the transmembrane and Q proteins of visna virus
CL Ruegg, JE Clements, M Strand |
Journal of virology | 1990 |
Markers of T Lymphocyte Activation in HLA-B8, DR3 Positive Individuals
MA Modica, AM Zambito, G Candore, C Caruso |
Immunobiology | 1990 |
CD8+ Lymphocytes from patients with systemic lupus erythematosus sustain, rather than suppress, spontaneous polyclonal IgG production and synergize with CD4+ cells to support autoantibody synthesis
M Linker-Israeli, FP Quismorio, DA Horwitz |
Arthritis & Rheumatism | 1990 |
HLA-DP+ T cells and deficient interleukin-2 production in patients with systemic lupus erythematosus
T Hishikawa, Y Tokano, I Sekigawa, S Ando, Y Takasaki, H Hashimoto, S Hirose, K Okumura, M Abe, T Shirai |
Clinical Immunology and Immunopathology | 1990 |
T lymphocyte subsets, suppressor and contrasuppressor cell functions, and production of interleukin-2 in the peripheral blood of rheumatic fever patients and their apparently healthy siblings
ME Alarcon-Riquelme, D Alarcon-Segovia, A Loredo-Abdala, J Alcocer-Varela |
Clinical Immunology and Immunopathology | 1990 |
Natural killer cell activity in Sjogren's syndrome and systemic lupus erythematosus: stimulation with interferons and interleukin-2 and correlation with immune complexes
NJ Struyf, HW Snoeck, CH Bridts, LS Clerck, WJ Stevens |
Annals of the rheumatic diseases | 1990 |
T helper-cell leukemia/lymphoma: Presentation as an acute immune-mediated illness
AJ Bridges, D Norback, P Fisch, D England, P Sondel |
Journal of Clinical Immunology | 1990 |
Effect of 1,1-dimethylhydrazine on lymphoproliferation and interleukin 2 immunoregulatory function
RM Bauer, MJ Tarr, RG Olsen |
Archives of Environmental Contamination and Toxicology | 1990 |
Immunotoxicity of Metals and Immunotoxicology
AD Dayan, RF Hertel, E Heseltine, G Kazantzis, EM Smith, MT der Venne |
1990 | |
Soluble interleukin-2 receptor, interleukin-2 and interleukin-4 in sera and supernatants from patients with progressive systemic sclerosis.
Famularo G, Procopio A, Giacomelli R, Danese C, Sacchetti S, Perego MA, Santoni A, Tonietti G |
Clinical & Experimental Immunology | 1990 |
The effect of the immunomodulator agent AS101 on interleukin-2 production in systemic lupus erythematosus (SLE) induced in mice by a pathogenic anti-DNA antibody.
Blank M, Sredni B, Albeck M, Mozes E, Shoenfeld Y |
Clinical & Experimental Immunology | 1990 |
A defect in immunoregulatory synovial fluid T cells in Behcet's syndrome
J Alcocer-Varela, A Laffon, C Abud-Mendoza, D Alarcon-Segovia |
Clinical Rheumatology | 1989 |
Natural killer cells and autoimmunity
E Grunebaum, E Malatzky-Goshen, Y Shoenfeld |
Immunologic Research | 1989 |
Familial Occurrence of impaired interleukin-2 activity and increased peripheral blood B cells actively secreting immunoglobulins in systemic lupus erythematosus
T Sakane, Y Murakawa, N Suzuki, Y Ueda, T Tsuchida, S Takada, Y Yamauchi, T Tsunematsu |
The American Journal of Medicine | 1989 |
Increased production of interleukin-2 and IL-2 receptor in primary IgA nephropathy
FP Schena, G Mastrolitti, E Jirillo, I Munno, N Pellegrino, AR Fracasso, L Aventaggiato |
Kidney International | 1989 |
Dysregulated Lymphokine Production in Systemic Lupus Erythematosus (SLE)
M Linker-Ismeli, R Deans |
Annals of the New York Academy of Sciences | 1989 |
Effect of the new immunoregulator AS-101 on in vitro functions of mononuclear cells from patients with systemic lupus erythematosus
J Alcocer-Varela, D Alarcon-Segovia, B Sredni, M Albeck |
Clinical & Experimental Immunology | 1989 |
T lymphocyte activation in systemic lupus erythematosus analysed by proliferative response to nucleoplasmic proteins on nitrocellulose immunoblots
BN Pham, L Prin, D Gosset, PY Hatron, B Devulder, A Capron, JP Dessaint |
Clinical & Experimental Immunology | 1989 |
Responsiveness of systemic lupus erythematosus T cells to signals provided through LCA T200 (CD45) and T1 (CD5) antigens
J Martorell, J Font, I Rojo, R Vilella, M Ingelmo, J Vives |
Clinical & Experimental Immunology | 1989 |
Relation between soluble interleukin 2 receptor and clinical findings in patients with systemic lupus erythematosus
Y Tokano, A Murashima, Y Takasaki, H Hashimoto, K Okumura, S Hirose |
Annals of the rheumatic diseases | 1989 |
Reversible interleukin-2 response defects in systemic lupus erythematosus
RJ Warrington, PJ Sauder, J Homik, W Ofosu-Appiah |
Clinical & Experimental Immunology | 1989 |
Cyclic AMP level of lymphocytes in patients with systemic lupus erythematosus and its relation to disease activity
N.C. Phi, Takáts, V.H. Binh, C.V. Vien, González-Cabello, P. Gergely |
Immunology Letters | 1989 |
Family Study of Natural Killer Cell Activity in C1qDeficient Patients with Systemic Lupus Erythematosus-Like Syndrome: Association between Impaired Natural Killer Cell Function and C1q Deficiency
J TóTh, Z Staršia, M Buc, J Štefanovič |
Immunobiology | 1989 |
Decreased expression of interleukin-2 binding molecules (p70/75) in T cells from patients with systemic lupus erythematosus
T Tanaka, O Saiki, S Negoro, T Igarashi, T Kuritani, H Hara, M Suemura, S Kishimoto |
Arthritis & Rheumatism | 1989 |
Two types of antibodies inhibiting interleukin-2 production by normal lymphocytes in patients with systemic lupus erythematosus
J Miyagi, N Minato, S Kano, M Sumiya, T Kasahara |
Arthritis & Rheumatism | 1989 |
Intravenous γ-globulin therapy in systemic lupus erythematosus and immune complex disease
SC Jordan |
Clinical Immunology and Immunopathology | 1989 |
B cell hyperresponsiveness to interleukin 2 and the age-associated decline in murine lupus
I Sekigawa, K Noguchi, K Hasegawa, S Hirose, H Sato, T Shirai |
Clinical Immunology and Immunopathology | 1989 |
In vitro effect of corticosteroid on immunoregulatory functions in primary biliary cirrhosis
T Ikeda, M Uchihara, Y Daiguji, Y Hasumura, J Takeuchi |
Clinical Immunology and Immunopathology | 1989 |
The role of natural killer cells in human disease
TL Whiteside, RB Herberman |
Clinical Immunology and Immunopathology | 1989 |
The role of interleukin 2 in autoimmunity
G Kroemer, G Wick |
Immunology Today | 1989 |
Pharmacology of the Skin I
MW Greaves, S Shuster |
1989 | |
B cell lymphokines in human systemic lupus erythematosus
PL Tan, M Blumenstein, S Yeoman, JD Watson |
Annals of the rheumatic diseases | 1989 |
Impaired T-cell activation in patients with systemic lupus erythematosus
S Sierakowski, EJ Kucharz, RW Lightfoot, JS Goodwin |
Journal of Clinical Immunology | 1989 |
Functions of the Natural Immune System
CW Reynolds, RH Wiltrout |
1989 | |
Decreased activity of interleukin-2 inhibitor in plasma of patients with systemic lupus erythematosus
EJ Kucharz, S Sierakowski, JS Goodwin |
Clinical Rheumatology | 1988 |
Discordant Interleukin 2 Production in Monozygotic Twins Concordant for Systemic Lupus Erythematosus
K Sato, N Miyasaka, K Yamaoka, T Yamada, T Nishido, M Okuda, K Nishioka |
Autoimmunity | 1988 |
Characterization of lymphocytes that suppress IL-2 production in systemic lupus erythematosus
M Linker-Israeli, JD Gray, FP Quismorio, DA Horwitz |
Clinical & Experimental Immunology | 1988 |
OKT4+ T cell deficiency and an association of immunoglobulin deficiency in systemic lupus erythematosus
S Raziuddin, BH Danial |
Clinical & Experimental Immunology | 1988 |
Impaired release of natural killer cytotoxic factor in patients with primary Sjögren's syndrome
BK Pedersen, P Oxholm |
Clinical & Experimental Immunology | 1988 |
Interleukin-2 production in Brown-Norway rats with HgCl2-induced autoimmune disease: paradoxical in vivo versus in vitro findings
D Baran, O Lantz, P Dosquet, A Sfaksi, P Druet |
Clinical & Experimental Immunology | 1988 |
Spontaneous recovery of the decreased expression in vitro of interleukin 2 receptors in rheumatoid arthritis
C Plater-Zyberk, KA Rockett, RN Maini |
Clinical & Experimental Immunology | 1988 |
Interleukin-2 production and response by helper T-cell subsets in man
M Salmon, GD Kitas, JS Gaston, PA Bacon |
Immunology | 1988 |
Deficient phytohemagglutinin-induced interleukin-2 activity in patients with inactive systemic lupus erythematosus is correctable by the addition of phorbol myristate acetate
Y Murakawa, T Sakane |
Arthritis & Rheumatism | 1988 |
Enhanced production of interleukin-2 in patients with progressive systemic sclerosis. hyperactivity of cd4-positive t cells?
H Umehara, S Kumagai, H Ishida, T Suginoshita, M Maeda, H Imura |
Arthritis & Rheumatism | 1988 |
Impaired mobility of human t lymphocyte surface molecules during inactive systemic lupus erythematosus. relationship to a defective camp pathway
GM Kammer, E Mitchell |
Arthritis & Rheumatism | 1988 |
Human recombinant interleukin-2125 induced in vitro proliferation of equine, caprine, ovine, canine and feline peripheral blood lymphocytes
BW Fenwick, CE Schore, BI Osburn |
Comparative Immunology, Microbiology and Infectious Diseases | 1988 |
Cellular and genetic analyses of IL-2 production and IL-2 receptor expression in a patient with familial T-cell-dominant immunodeficiency
S Doi, O Saiki, T Tanaka, K Ha-Kawa, T Igarashi, T Fujita, T Taniguchi, S Kishimoto |
Clinical Immunology and Immunopathology | 1988 |
Role of interleukin 2 in inducing normalization of natural killer activity in systemic lupus erythematosus
ML Gaspar, M Alvarez-Mon, C Gutiérrez |
Clinical Immunology and Immunopathology | 1988 |
OKT4+ T cell abnormality in patients with active systemic lupus erythematosus: HLA-DR antigen expressions
S Raziuddin, HB Danial, M Kelley |
Clinical Immunology and Immunopathology | 1988 |
Interleukin 2 receptor bearing T lymphocytes in patients with chronic liver disease
S Kakumu, K Yoshioka, A Fuji, H Tahara |
Gastroenterologia Japonica | 1988 |
Basis for Variability of Response to Anti-Rheumatic Drugs
PM Brooks, RO Day, K Williams, G Graham |
1988 | |
The B-cell activation pathway in human systemic lupus erythematosus: Imbalancedin vitro production of lymphokines and association with serum analytical findings
ML Gaspar, M Alvarez-Mon, C Gutierrez |
Journal of Clinical Immunology | 1988 |
Increased serum levels of soluble interleukin-2 receptor in patients with systemic lupus erythematosus and rheumatoid arthritis
G Semenzato, LM Bambara, D Biasi, A Frigo, F Vinante, B Zuppini, L Trentin, C Feruglio, M Chilosi, G Pizzolo |
Journal of Clinical Immunology | 1988 |
Production of and response to interleukin-2 in Graves' disease
Z Eisenstein, E Engelsman, M Weiss, Y Kalechman, B Sredni |
Journal of Clinical Immunology | 1988 |
Immunopathogenetic Mechanisms of Arthritis
JA Goodacre, WC Dick |
1988 | |
Interleukin-1-production by monocytes from patients with systemic lupus erythematosus
S Sierakowski, EJ Kucharz, RW Lightfoot, JS Goodwin |
Clinical Rheumatology | 1987 |
Cellular immunity and IgE levels in atopic patients
M Frajman, L González, A Alvarado, J Yock |
Allergy | 1987 |
Decreased Production of Interleukin-2 in Schizophrenia
F Villemain, L Chatenoud, E Guillibert, Y Pelicier, JF Bach |
Annals of the New York Academy of Sciences | 1987 |
The role of L3T4+ cells in the pathogenesis of lupus inlpr-bearing mice. I. Defects in the production of interleukins 2 and 3
TJ Santoro, KR Lehmann, RA Batt, BL Kotzin |
European Journal of Immunology | 1987 |
Studies on human blood lymphocytes with iC3b (type 3) complement receptors: III. Abnormalities in patients with active systemic lupus erythematosus
JD Gray, A Lash, AC Bakke, RC Kitridou, DA Horwitz |
Clinical & Experimental Immunology | 1987 |
Failure of exogenous interleukin 1 and interleukin 2 to correct decreased lymphocyte transformation in chronic hepatitis B virus carriers
C Anastassakos, GJ Alexander, RA Wolstencroft, DC Dumonde, AL Eddleston, R Williams |
Clinical & Experimental Immunology | 1987 |
Production of and responsiveness to interleukin 2 in autoimmune BXSB mice
SP Umland, SR Smith, HR Strausser |
Cellular Immunology | 1987 |
A review of mechanism of action of aspirin and its potential as an immunomodulating agent
MM Rumore, SM Aron, EJ Hiross |
Medical Hypotheses | 1987 |
Immunologic alterations in MRL/lpr mice after chronic dimethyl sulfoxide administration
AJ Wysenbeek, S Lourie, A Weinberger, N Schoenfeld, AI Pick, M Pecht |
International Journal of Immunopharmacology | 1987 |
The effect of adherent cell-derived factors on immunoglobulin and anti-DNA synthesis in systemic lupus erythematosus
RC Jandl, JL George, DS Silberstein, RB Eaton, PH Schur |
Clinical Immunology and Immunopathology | 1987 |
Interleukin 2 Receptors and Responsiveness to Recombinant Human Interleukin 2 in Patients With Systemic Lupus Erythematosus
S Lakhanpal, BS Handwerger |
Mayo Clinic Proceedings | 1987 |
Lymphokines
HM Johnson, BA Torres |
Lymphokines | 1987 |
Lymphocyte Subpopulations in Bronchoalveolar Lavage in Sjögren's Syndrome
B Wallaert, L Prin, PY Hatron, P Ramon, AB Tonnel, C Voisin |
Chest | 1987 |
The Role of T Lymphocytes in Autoimmune Thyroid Disease
AJ Ahmann, KD Burman |
Endocrinology and metabolism clinics of North America | 1987 |
Mechanisms of rhysiologic B cell responses and B cell hyperactivity in systemic lupus erythematosus
RH Zubler, YP Huang, PA Miescher |
Springer Seminars in Immunopathology | 1986 |
Mechanisms of immunosuppression associated with severe nonthermal traumatic injuries in man: Production of interleukin 1 and 2
ML Rodrick, J Wood, JB O'Mahony, CF Davis, JT Grbic, RH Demling, NM Moss, I Saporoschetz, A Jordan, P D'Eon, JA Mannick |
Journal of Clinical Immunology | 1986 |
B cell hyperactivity in systemic lupus erythematosus: selectively enhanced responsiveness to a high molecular weight B cell growth factor
JF Delfraissy, C Wallon, A Vazquez, B Dugas, J Dormont, P Galanaud |
European Journal of Immunology | 1986 |
Recombinant interleukin 2 enhances spontaneous insulin-dependent diabetes in BB rats
H Kolb, J Zielasek, U Treichel, G Freytag, M Wrann, U Kiesel |
European Journal of Immunology | 1986 |
Stimulating and differentiation factors for human B lymphocytes in systemic lupus erythematosus
E Martinez-Cordero, J Alcocer-Varela, D Alarcon-Segovia |
Clinical & Experimental Immunology | 1986 |
Systemic lupus erythematosus sera antilymphocyte reactivity: detection of antibodies to Tac-antigen positive T cell lines
H Sano, S Kumagai, S Namiuchi, T Uchiyama, J Yodoi, M Maeda, K Takatsuki, T Suginoshita, H Imura |
Clinical & Experimental Immunology | 1986 |
Interleukin 2 defect in the peripheral blood and the lung in patients with Sjögren's syndrome
N Miyasaka, N Murota, K Yamaoka, K Sato, T Yamada, T Nishido, M Okuda |
Clinical & Experimental Immunology | 1986 |
Effects of LS-2616 administration upon the autoimmune disease of (NZB x NZW) F1 hybrid mice
A Tarkowski, K Gunnarsson, T Stålhandske |
Immunology | 1986 |
Independence of depressed lectin-dependent cell-mediated cytotoxicity from interleukin 2 production in patients with systemic lupus erythematosus
A Perl, R González-Cabello, K Onody, I Bodó, P Gergely |
Clinical & Experimental Immunology | 1986 |
T cell function in systemic lupus erythematosus: normal production of and responsiveness to interleukin 2
AM Draeger, AJ Swaak, HG van Brink, LA Aarden |
Clinical & Experimental Immunology | 1986 |
Modulation of cellular immune responses in mice with disseminated histoplasmosis by recombinant interleukin-2
GS Deepe, CL Taylor, JE Harris, WE Bullock |
Infection and immunity | 1986 |
Administration of group A streptococcal cell walls to rats induces an interleukin 2 deficiency
SC Ridge, JB Zabriskie, H Osawa, T Diamantstein, AL Oronsky, SS Kerwar |
Journal of Experimental Medicine | 1986 |
Cell-mediated immunity in rheumatic disease
SJ Padula, RB Clark, JH Korn |
Human Pathology | 1986 |
A human T cell line established from a patient with Sézary syndrome
S Namiuchi, S Kumagai, H Sano, J Yodoi, T Uchiyama, K Ikai, H Imura, M Maeda |
Journal of Immunological Methods | 1986 |
Human interleukin 2
JM Cardenas, P Marshall, B Henderson, A Altman |
Journal of Immunological Methods | 1986 |
Detection of impaired T cell-mediated immune responses to herpesvirus (BHV-1) in cattle
M Miller-Edge, G Splitter |
Veterinary Immunology and Immunopathology | 1986 |
Effect of anti-T cell auto antibodies from systemic lupus erythematosus sera upon T lymphocyte functions
LP Goldschmidt, TF Kresina, GM Kammer |
Arthritis & Rheumatism | 1986 |
Analysis of interleukin-2 activity in patients with Behçet's disease. Ability of T cells to produce and respond to interleukin-2
T Sakane, N Suzuki, Y Ueda, S Takada, Y Murakawa, T Hoshino, Y Niwa, T Tsunematsu |
Arthritis & Rheumatism | 1986 |
Successful treatment of autoimmunity in mrl/1 mice with ls-2616, a new immunomodulator
A Tarkowski, K Gunnarsson, LÅ Nilsson, L Lindholm, T Stålhandske |
Arthritis & Rheumatism | 1986 |
Deficient γ-interferon production in patients with systemic lupus erythematosus
GC Tsokos, DT Boumpas, PL Smith, JY Djeu, JE Balow, AH Rook |
Arthritis & Rheumatism | 1986 |
T-cell dysregulation in patients with hyperprolactinemia: Effect of bromocriptine treatment
A Vidaller, L Llorente, F Larrea, JP Mendez, J Alcocer-Varela, D Alarcon-Segovia |
Clinical Immunology and Immunopathology | 1986 |
Perceived interleukin 2 deficiency and T cell function: Implications for treating autoimmune disorders
MH Bocchieri, JB Smith |
Clinical Immunology Newsletter | 1986 |
Interleukin 2 production in patients with thyroid diseases
VV Malaitsev, IM Bogdanova, EN Shatsova |
Bulletin of Experimental Biology and Medicine | 1986 |
Correction of interleukin-2 production in patients with systemic lupus erythematosus by removal of spontaneously activated suppressor cells
M Linker-Israeli, AC Bakke, FP Quismorio, DA Horwitz |
Journal of Clinical Investigation | 1985 |
Enhancement of the impaired autologous mixed leukocyte reaction in patients with systemic lupus erythematosus
MK Crow |
Journal of Clinical Investigation | 1985 |
Abnormalities in autologous mixed lymphocyte reaction-activated immunologic processes in systemic lupus erythematosus and their possible correction by interleukin 2
S Takada, Y Ueda, N Suzuki, Y Murakawa, T Hoshino, I Green, AD Steinberg, DA Horwitz, T Sakane |
European Journal of Immunology | 1985 |
Abnormal Production of and Response to B-Cell Growth Factor and B-Cell Differentiation Factor in Patients with Systemic Lupus Erythematosus
T Hirose, M Hara, A Kitani, W Hirose, K Norioka, M Kawagoe, H Nakamura |
Scandinavian Journal of Immunology | 1985 |
Immunoregulatory circuits in the acquired immune deficiency syndrome and related complex. Production of and response to interleukins 1 and 2, NK function and its enhancement by interleukin-2 and kinetics of the autologous mixed lymphocyte reaction
J Alcocer-Varela, D Alarcon-Segovia, C Abud-Mendoza |
Clinical & Experimental Immunology | 1985 |
Interleukin-2 in rheumatoid arthritis: production of and response to interleukin-2 in rheumatoid synovial fluid, synovial tissue and peripheral blood
B Combe, RM Pope, M Fischbach, B Darnell, S Baron, N Talal |
Clinical & Experimental Immunology | 1985 |
Functional consequences of perceived interleukin deficiencies? Analysis employing NZB x C58 recombinant inbred mice
MH Bocchieri, JB Smith, JB Smith, MJ Staruch, DD Wood |
Clinical & Experimental Immunology | 1985 |
Spontaneous production of, and defective response to, interleukin-1 by peripheral blood mononuclear cells from patients with scleroderma
J Alcocer-Varela, E Martinez-Cordero, D Alarcon-Segovia |
Clinical & Experimental Immunology | 1985 |
Comparison of the biological properties of purified natural and recombinant human interleukin-2
K Naruo, S Hinuma, K Kato, M Koyama, H Tada, O Shiho, K Tsukamoto |
Biochemical and Biophysical Research Communications | 1985 |
Staining and fluorescence-activated cell sorter analysis of human lymphocytes using antibodies to a short, chemically synthesized human IL-2 peptide
N Isakov, RI Fox, FJ Dixon, AN Theofilopoulos, A Altman |
Cellular Immunology | 1985 |
Immunohistochemical studies of interleukin-2 and γ-interferon in rheumatoid arthritis
G Husby, RC Williams |
Arthritis & Rheumatism | 1985 |
Relationship between circulating interferon and anti-interferon antibodies and impaired natural killer cell activity in systemic lupus erythematosus
WL Sibbitt, DL Gibbs, C Kenny, AD Bankhurst, RP Searles, KD Ley |
Arthritis & Rheumatism | 1985 |
Interleukin-2 restores the depressed allogeneic cell-mediated lympholysis and natural killer cell activity in patients with systemic lupus erythematosus
GC Tsokos, PL Smith, CB Christian, RN Lipnick, JE Balow, JY Djeu |
Clinical Immunology and Immunopathology | 1985 |
Experimental models for systemic autoimmune disease—Current concepts
AN Theofilopoulos, MT Aguado |
Clinical Immunology Newsletter | 1985 |
Mechanism of action of thymosin. II. Effects of aspirin and thymosin on enhancement of IL-2 production
MM Zatz, A Skotnicki, JM Bailey, JH Oliver, AL Goldstein |
Immunopharmacology | 1985 |
Radiosensitivity of Peripheral Blood Lymphocytes in Autoimmune Disease
G Harris, WA Cramp, JC Edwards, AM George, SA Sabovljev, L Hart, GR Hughes, AM Denman, MB Yatvin |
International Journal of Radiation Biology and Related Studies in Physics, Chemistry and Medicine | 1985 |
Immunology of Rheumatic Diseases
S Gupta, N Talal |
1985 | |
Interleukin-2 production by persons with the generalized lymphadenopathy syndrome or the acquired immune deficiency syndrome
CH Kirkpatrick, KC Davis, CR Horsburgh, DL Cohn, K Penley, FN Judson |
Journal of Clinical Immunology | 1985 |
Lymphocyte function in human bone marrow. II. Characterization of an interleukin 2-sensitive T precursor-cell population
HM Dosch, CJ Ledgley, D White, P Lam, GB Mills |
Journal of Clinical Immunology | 1985 |
Anti-lymphocyte Antibodies in Systemic Lupus Erythematosus
JB Winfield |
Clinics in rheumatic diseases | 1985 |
The Connective Tissue Diseases as Disorders of Immune Regulation
D Alarcon-Segovia, J Alcocer-Varela, E Diaz-Jouanen |
Clinics in rheumatic diseases | 1985 |
Interleukins, Interferon and Rheumatic Disease
N Talal |
Clinics in rheumatic diseases | 1985 |
Natural Killer Cells in Connective Tissue Disorders
WL Sibbitt, AD Bankhurst |
Clinics in rheumatic diseases | 1985 |
Interleukin-2 production in bullous pemphigoid
AR Ahmed, K Hijri, V Arab-Kermani |
Archives of Dermatological Research | 1984 |
B Cell-Tropic Interleukins in Murine Systemic Lupus Erythematosus (SLE) 1
GJ Prud-Homme, TM Fieser, FJ Dixon&, AN Theoflopoulos |
Immunological Reviews | 1984 |
Deficiency of Interleukin-2 Production and Interleukin-2 Receptor Expression on Peripheral Blood Leukocytes after Phytohemagglutinin Stimulation in Pemphigus
V Kermani-Arab, K Hirji, AR Ahmed, JL Fahey |
Journal of Investigative Dermatology | 1984 |
Defective monocyte production of, and T lymphocyte response to, interleukin-1 in the peripheral blood of patients with systemic lupus erythematosus
J Alcocer-Varela, A Laffon, D Alarcón-Segovia |
Clinical & Experimental Immunology | 1984 |
Defective LN cell proliferative response to Sm antigen in mice bearing the lpr gene
H Dang, M Fischbach, V Fey, N Talal |
Clinical & Experimental Immunology | 1984 |
Interleukin-2 activity in chronic active liver diseases: response by T cells and in the autologous mixed lymphocyte reaction
K Yoshioka, S Kakumu, H Murakami, K Fukui |
Clinical & Experimental Immunology | 1984 |
Antibodies of predetermined specificity against chemically synthesized peptides of human interleukin 2
A Altman, JM Cardenas, RA Houghten, FJ Dixon, AN Theofilopoulos |
Proceedings of the National Academy of Sciences | 1984 |
Cell-mediated immunodeficiency in Down's syndrome: normal IL-2 production but inverted ratio of T cell subsets
R Karttunen, T Nurmi, J Ilonen, HM Surcel |
Clinical & Experimental Immunology | 1984 |
Interleukin-2 reverses deficient cell-mediated immune responses in rheumatoid arthritis
P Emery, GS Panayi, AM Nouri |
Clinical & Experimental Immunology | 1984 |
Increased Ia expression, T lymphocyte subset abnormalities and autoimmunity in murine strains bearing the lpr gene
MJ Dauphinée, N Talal |
Clinical & Experimental Immunology | 1984 |
Interleukin 2 enhances natural killing of normal lymphocytes
N Miyasaka, B Darnell, S Baron, N Talal |
Cellular Immunology | 1984 |
Canine Il-2: Characterization and optimal conditions for production
AJ Daemen, WA Buurman, CJ Linden, G Groenewegen, G Kootstra |
Veterinary Immunology and Immunopathology | 1984 |
Cytokine production by NZB, C58, and NZB × C58 recombinant inbred mice
MH Bocchieri, L Knittweis, DS Seaton |
Cellular Immunology | 1984 |
Effects of prostaglandin E2 on responses of T-cell subsets to mitogen and autologous non-T-cell stimulation
M Honda, AD Steinberg |
Clinical Immunology and Immunopathology | 1984 |
Impaired IL2 production by lymphocytes of patients with systemic lupus erythematosus
P Faucal, A Godard, MA Peyrat, JF Moreau, JP Soulillou |
Annales de l'Institut Pasteur / Immunologie | 1984 |
Lymphoid abnormalities in rats with adjuvant-induced arthritis. I. Mitogen responsiveness and lymphokine synthesis
SC Gilman, JF Daniels, RE Wilson, RP Carlson, AJ Lewis |
Annals of the rheumatic diseases | 1984 |
Differences in the production of and/or the response to interleukin-2 by T lymphocytes from patients with the various connective tissue diseases
J Alcocer-Varela, A Laffn, D Alarcn-Segovia |
Rheumatology International | 1984 |
Natural killer cell-mediated activity in mixed connective tissue disease and its response to induction by interleukin-2
R Gonzlez-Amaro, J Alcocer-Varela, E Martnez-Cordero, D Alarcn-Segovia |
Journal of Clinical Immunology | 1984 |
Interleukin 2 Activity of Human Intestinal Mucosa Mononuclear Cells
C Fiocchi, ML Hilfiker, KR Youngman, NC Doerder, JH Finke |
Gastroenterology | 1984 |
Impaired T cell capping and receptor regeneration in active systemic lupus erythematosus. Evidence for a disorder intrinsic to the T lymphocyte
GM Kammer |
Journal of Clinical Investigation | 1983 |
Mechanisms of autoimmunity: a role for cross-reactive idiotypes
A Cooke, PM Lydyard, IM Roitt |
Immunology Today | 1983 |
Abnormalities of immune regulation in the connective tissue diseases
HE Jasin |
Seminars in Arthritis and Rheumatism | 1983 |
Mixed connective tissue disease: A disorder of immune regulation
D Alarcón-Segovia |
Seminars in Arthritis and Rheumatism | 1983 |
Cellular bases of the production of and response to interleukin-2 in man: role of autologous rosette-forming T-cell subsets defined with monoclonal antibodies
E Fishbein, J Alcocer-Varela, D Alarcón-Segovia |
Immunology | 1983 |
Molecular cloning of human interleukin 2 cDNA and its expression in E. coli
R Devos, G Plaetinck, H Cheroutre, G Simons, W Degrave, J Tavernier, E Remaut, W Fiers |
Nucleic Acids Research | 1983 |
Natural Killer Cells in Systemic Lupus Erythematosus
ML Egan, SL Mendelsohn, T Abo, CM Balch |
Arthritis & Rheumatism | 1983 |
Mouse monoclonal antibodies can nonspecifically inhibit the proliferation of human T-cell growth factor-dependent T cells
GF Burns, T Triglia, GA Varigos |
Cellular Immunology | 1983 |
Impaired natural killer cell function in systemic lupus erythematosus
WL Sibbitt, L Likar, CW Spellman, AD Bankhurst |
Arthritis & Rheumatism | 1983 |
The autologous mixed lymphocyte reaction is not primarily due to xenoantigenic stimulation
A Laffón, J Alcocer-Varela, D Alarcón-Segovia |
Clinical Immunology and Immunopathology | 1983 |
B-cell hyperactivity in murine lupus II. Defects in response to and production of accessory signals in lupus-prone mice
AN Theofilopoulos, GJ Prud'homme, TM Fieser, FJ Dixon |
Immunology Today | 1983 |
Differences in the kinetics of the autologous mixed lymphocyte reaction between the various connective tissue diseases
A Laffón, J Alcocer-Varela, D Alarcón-Segovia |
Rheumatology International | 1983 |
Autoantibodies
MH Lessof, SP Asper |
American Heart Journal | 1960 |