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Research Article Free access | 10.1172/JCI110387

Immunoglobulin allotypes and immune response to meningococcal group B polysaccharide.

J P Pandey, W D Zollinger, H H Fudenberg, and C B Loadholt

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Published November 1, 1981 - More info

Published in Volume 68, Issue 5 on November 1, 1981
J Clin Invest. 1981;68(5):1378–1380. https://doi.org/10.1172/JCI110387.
© 1981 The American Society for Clinical Investigation
Published November 1, 1981 - Version history
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Abstract

Serum samples were collected from 120 healthy adult volunteers (105 Caucasians and 15 Negros) before and after immunization with meningococcal polysaccharide (MPS) group B vaccine. Antibodies to MPS group B were measured and sera were typed for several Gm and Km(1) allotypes. A significant association was found between the Km(1) allotype and immune response to MPS group B in Caucasians.

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