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Citations to this article

Stimulation of human eosinophil and neutrophil polymorphonuclear leukocyte chemotaxis and random migration by 12-L-hydroxy-5,8,10,14-eicosatetraenoic acid.
E J Goetzl,, … , J M Woods, R R Gorman
E J Goetzl,, … , J M Woods, R R Gorman
Published January 1, 1977
Citation Information: J Clin Invest. 1977;59(1):179-183. https://doi.org/10.1172/JCI108617.
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Research Article

Stimulation of human eosinophil and neutrophil polymorphonuclear leukocyte chemotaxis and random migration by 12-L-hydroxy-5,8,10,14-eicosatetraenoic acid.

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Abstract

A human platelet lipoxygenase-generated product of arachidonic acid, identified by thin-layer chromatographic and mass spectrometric properties as 12-L-hydroxy-5,8,10,14-eicosatertraenoic acid (HETE), was selectively chemotactic in vitro for human polymorphonuclear leukocytes (PMN), as compared to mononuclear leukocytes, with a preference for eosinophils. Preincubation of PMN with partially-purified HETE at peak chemotactic concentrations of 8-24 mug/ml reduced their random and chemotactic migration and stimulated the activity of their hexose monophosphate shunt; minimally chemotactic concentrations of 0.03-1 mug/ml enhanced PMN random migration without influencing other functions. HETE may thus be capable of preferentially attracting eosinophils to foci of tissue reaction associated with platelet activation.

Authors

E J Goetzl,, J M Woods, R R Gorman

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WE Lands
1985
Drugs Affecting Leukotrienes and Other Eicosanoid Pathways
B Samuelsson, F Berti, GC Folco, GP Velo
1985
Mechanisms of Cancer Metastasis
KV Honn, WE Powers, BF Sloane
1985
Oxygen-free radicals and lipid peroxidation in adult respiratory distress syndrome
Y Bertrand
Intensive Care Medicine 1985
Eosinophil-mediated injury to lung parenchymal cells and interstitial matrix. A possible role for eosinophils in chronic inflammatory disorders of the lower respiratory tract
WB Davis, GA Fells, XH Sun, JE Gadek, A Venet, RG Crystal
Journal of Clinical Investigation 1984
Biologically active complement (C5)-derived peptides and their relevance to disease
HD Perez
Critical Reviews in Oncology/Hematology 1984
Diminished production of thromboxane B2 and prostaglandin E by stimulated polymorphonuclear leukocytes from insulin-treated diabetic subjects
R Qvist, RG Larkins
Agents and Actions 1984
The human lung mast cell
SI Wasserman
Environmental Health Perspectives 1984
Cell population and histochemistry of asbestos related lesions of rat pleural cavity after injection of various inorganic dusts
RE Edwards, MM Wagner, CB Moncrieff
British journal of industrial medicine 1984
The effect of etretinate on the cyclo-oxygenase and lipoxygenase products of arachidonic acid metabolism in psoriatic skin
E Wong, RM Barr, SD Brain, MW Greaves, LA Olins, AI Mallet
British Journal of Clinical Pharmacology 1984
Effects of non-steroidal anti-inflammatory agents on human neutrophil functions in vitro and in vivo
HB Kaplan, HS Edelson, HM Korchak, WP Given, S Abramson, G Weissmann
Biochemical Pharmacology 1984
Effect of indomethacin on generation of chemotactic activity in inflammatory exudates induced by carrageenan
TN Lo, AP Almeida, MA Beaven
European Journal of Pharmacology 1984
Immunodermatology
RE Schopf, M Jung, B Morsches, K Bork
Immunodermatology 1984
Regulation of Leukocyte Function
R Snyderman
1984
Immunobiology of the Head and Neck
JF Poliquin, AF Ryan, JP Harris
1984
Omega-hydroxylation of 12-L-hydroxy-5,8,10,14-eicosatetraenoic acid in human polymorphonuclear leukocytes
PY Wong, P Westlund, M Hamberg, E Granström, PH Chao, B Samuelsson
The Journal of biological chemistry 1984
Anthralin Inhibition of Mouse Epidermal Arachidonic Acid Lipoxygenase In Vitro
CJ Bedord, JM Young, BM Wagner
Journal of Investigative Dermatology 1983
Cigarette smoking stimulates lipoxygenase but not cyclooxygenase pathway in platelets
WC Chang, S Fukuda, HH Tai
Biochemical and Biophysical Research Communications 1983
Reactive oxygen production by cultured rat glomerular mesangial cells during phagocytosis is associated with stimulation of lipoxygenase activity
L Baud, J Hagege, J Sraer, E Rondeau, J Perez, R Ardaillou
Journal of Experimental Medicine 1983
Experimental production of pulmonary granulomas. IV. Eosinophilic granuloma
Y Hamamoto, K Kinoshita, K Hashimoto, T Matsushita, K Kogishi, K Yasuhira
British Journal of Experimental Pathology 1983
Antipsoriatic drugs as inhibitors of soybean lipoxygenase. A possible mode of action
JC Sircar, CF Schwender
Prostaglandins, Leukotrienes and Medicine 1983
Differential effects of anti-inflammatory drugs on lipoxygenase and cyclo-oxygenase activities of neutrophils from a reverse passive Arthus reaction
RF Myers, MI Siegel
Biochemical and Biophysical Research Communications 1983
Reductive Drug Metabolism
KE McLane, J Fisher, K Ramakrishnan
Drug Metabolism Reviews 1983
Platelets and the Inflammatory Response
BB Weksler
Clinics in Laboratory Medicine 1983
Immunologie in Anaesthesie und Intensivmedizin
A Doenicke, UD Koenig, S Doenicke
1983
Metabolism of arachidonic acid via the lipoxygenase pathway in human and murine glomeruli
J Sraer, M Rigaud, M Bens, H Rabinovitch, R Ardaillou
The Journal of biological chemistry 1983
Metabolites of arachidonic acid
W F Stenson, C W Parker
Clinical Reviews in Allergy 1983
Chemotaxis of monocytes and neutrophils to platelet-derived growth factor
TF Deuel, R M, JS Huang, GL Griffin
Journal of Clinical Investigation 1982
Soybean lipoxygenase-1 inhibition by ketone hydrazones
J Baumann, G Wurm
Agents and Actions 1982
Leukotrienes, allergy and inflammation
FP Nijkamp, JM Sitsen
Pharmaceutisch Weekblad Scientific Edition 1982
Mediators of cellular immune reactions
JM Hanson, VM Rumjanek, J Morley
Pharmacology & Therapeutics 1982
Comparative effect of lipoxygenase products of arachidonic acid on rat aortic smooth muscle cell migration
J Nakao, T Ooyama, H Ito, WC Chang, S Murota
Atherosclerosis 1982
Platelets stimulate aortic smooth muscle cell migration in vitro
J Nakao, T Ooyama, WC Chang, S Murota, H Orimo
Atherosclerosis 1982
Modulation of antigen-induced leukocyte adherence inhibition by metabolites of arachidonic acid and intracellular nucleotides
DM Thomson, K Phelan, R Scanzano, A Fink
International Journal of Cancer 1982
Mast cells in allergic diseases and mastocytosis
DL Marquardt, SI Wasserman
The Western journal of medicine 1982
Polymorphonuclear leukocyte activation by a synthetic muramyl dipeptide analog
Y Osada, T Otani, M Sato, T Une, K Matsumoto, H Ogawa
Infection and immunity 1982
The functional and physicochemical characterization of three eosinophilotactic activities released into the circulation by cold challenge of patients with cold urticaria
SI Wasserman, KF Austen, NA Soter
Clinical & Experimental Immunology 1982
Mitochondrial N-formylmethionyl proteins as chemoattractants for neutrophils
H Carp
Journal of Experimental Medicine 1982
Phenolic anticyclooxygenase agents in antiinflammatory and analgesic therapy
WE Lands, AM Hanel
Prostaglandins 1982
The lipoxygenase product, 5-hydroperoxy-arachidonic acid, augments chemotactic peptide-stimulated arachidonic acid release from HL60 granulocytes
MI Siegel, RT McConnell, RW Bonser, P Cuatrecasas
Biochemical and Biophysical Research Communications 1982
Decreased phospholipase A2 activity and prostaglandin biosynthesis in Bacillus Calmette-Guérin-activated alveolar macrophages
W Hsueh, R Lamb, F Gonzalez-Crussi
Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism 1982
Phagocytosis–Past and Future
FB Bang
Phagocytosis–Past and Future 1982
Studies on glycogen-induced inflammation of mice: Dynamics of inflammatory responses and influence of antiinflammatory drugs and protease inhibitors
T Yamashita, Y Ishibashi, I Nagaoka, K Kasuya, K Masuda, H Warabi, Y Shiokawa
Inflammation 1982
Prostaglandins and dermatology. The Ingram Lecture 1982
M W Greaves
Journal of the Royal College of Physicians of London 1982
Biology of the mast cell and its role in cutaneous inflammation
BU Wintroub, NA Soter
Springer Seminars in Immunopathology 1981
Anti-inflammatory steroids — the pharmacological and biochemical basis of clinical activity
IF Skidmore
Molecular Aspects of Medicine 1981
Actions of anti-inflammatory drugs
WE Lands
Trends in Pharmacological Sciences 1981
Eosinophilic Granulocytes and Skin Disorders
PJ Berretty, RH Cormane
International Journal of Dermatology 1981
Effect of arachidonic acid and the chemotactic factor F-Met-Leu-Phe on cation transport in rabbit neutrophils
RI Sha'Afi, PH Naccache, T Alobaidi, TF Molski, M Volpi
Journal of Cellular Physiology 1981
Lipoxygenase products modulate histamine release in human basophils
SP Peters, MI Siegel, A Kagey-Sobotka, LM Lichtenstein
Nature 1981
Two phospholipase pools for prostaglandin synthesis in macrophages
W Hsueh, U Desai, F Gonzalez-Crussi, R Lamb, A Chu
Nature 1981
Role of essential fatty acids in cutaneous wound healing in rats
BB Caffrey, HT Jonsson
Progress in Lipid Research 1981
Platelet factor 4 is chemotactic for neutrophils and monocytes
TF Deuel, R M, D Chang, GL Griffin, RL Heinrikson, ET Kaiser
Proceedings of the National Academy of Sciences 1981
Neutrophil-aggregating activity of monohydroxyeicosatetraenoic acids
JT O'Flaherty, MJ Thomas, CJ Lees, CE McCall
The American Journal of Pathology 1981
Concanavalin A-induced chemiluminescence in rat thymus lymphocytes. Its origin and role in mitogenesis
DA Hume, K Wrogemann, E Ferber, ME Kolbuch-Braddon, RM Taylor, H Fischer, MJ Weidemann
Biochemical Journal 1981
IgE antibody and resistance to infection. I. Selective suppression of the IgE antibody response in rats diminishes the resistance and the eosinophil response to Trichinella spiralis infection
AJ Dessein, WL Parker, SL James, JR David
Journal of Experimental Medicine 1981
The production of 5-HETE and leukotriene B in rat neutrophils from carrageenan pleural exudates
MI Siegel, RT McConnell, RW Bonser, P Cuatrecasas
Prostaglandins 1981
The effects of arachidonic and other fatty acids on canine neutrophil metabolism
BR Andersen, HJ Amirault, GC LeBreton
Prostaglandins 1981
Current Topics in Cellular Regulation
G Cahill, T Aoki, R Smith
Current Topics in Cellular Regulation 1981
The role of arachidonate lipoxygenase and fatty acids during irreversible blood platelet aggregation in vitro
CE Dutilh, E Haddeman, JA Don, F Hoor
Prostaglandins and Medicine 1981
Factors affecting the initial rate of lipoxygenase catalysis
MO Funk, SH Kim, AW Alteneder
Biochemical and Biophysical Research Communications 1981
Polymyalgia rheumatica and giant cell arteritis—Rational diagnosis and treatment predicated on disordered prostaglandin metabolism
RM Nalbandian, RL Henry, GA Williams, JA Fleischman, FE O'Donnell, FH Reeser
Medical Hypotheses 1981
Chemotactic peptide stimulated endogenous arachidonic acid metabolism in HL60 granulocytes
RW Bonser, MI Siegel, RT McConnell, P Cuatrecasas
Biochemical and Biophysical Research Communications 1981
Interactions of sulfhydryl agents and soybean lipoxygenase inhibitors
I Knippel, J Baumann, F Bruchhausen, G Wurm
Biochemical Pharmacology 1981
The appearance of phospholipase and cyclo-oxygenase activities in the human promyelocytic leukemia cell line HL60 during dimethyl sulfoxide-induced differentiation
RW Bonser, MI Siegel, RT McConnell, P Cuatrecasas
Biochemical and Biophysical Research Communications 1981
EXACERBATION OF PSORIASIS INDUCED BY INDOMETHACIN
H Katayama, A Kawada
The Journal of Dermatology 1981
Eosinophil, Eosinophilic and Eosinophilic Disorders
M Tavassoli, MH Steinberg
Critical Reviews in Clinical Laboratory Sciences 1981
Hemostasis, Thrombosis, and Thromboembolic Disorders: The Role of Arachidonic Acid Metabolites in Platelet-Vessel Wall Interactions
JM Harlan, LA Harker
Medical Clinics of North America 1981
Oxygenation Products of Arachidonic Acid as Mediators of Hypersensitivity and Inflammation
EJ Goetzl
Medical Clinics of North America 1981
The Prostaglandin System
F Berti, GP Velo
1981
The Lymphokines
JW Hadden, WE Stewart
1981
The Prostaglandin System: Endoperoxides, Prostacyclin, and Thromboxanes
F Berti, GP Velo
1981
Prostaglandine in Gynäkologie und Geburtshilfe
H Hepp, B Schüßler
1981
Oxidation of arachidonic acid in micelles by superoxide and hydrogen peroxide
SE Fridovich, NA Porter
The Journal of biological chemistry 1981
Regional synthesis of monohydroxy eicosanoids by the kidney
TS Winokur, AR Morrison
The Journal of biological chemistry 1981
Alveolar macrophage-derived chemotactic factor: kinetics of in vitro production and partial characterization
WW Merrill, GP Naegel, RA Matthay, HY Reynolds
Journal of Clinical Investigation 1980
Thromboxane A2 Mediates Augmented Polymorphonuclear Leukocyte Adhesiveness
PJ Spagnuolo, JJ Ellner, A Hassid, MJ Dunn
Journal of Clinical Investigation 1980
Human Alveolar Macrophage-derived Chemotactic Factor for Neutrophils STIMULI AND PARTIAL CHARACTERIZATION
GW Hunninghake, JE Gadek, HM Fales, RG Crystal
Journal of Clinical Investigation 1980
Generation of a chemotactic lipid from arachidonic acid by exposure to a superoxide-generating system
HD Perez, BB Weksler, IM Goldstein
Inflammation 1980
Lipoxygenase products and the polymorphonuclear leucocyte
AW Ford-Hutchinson, MA Bray, MJ Smith
Agents and Actions 1980
Effect of calcium, magnesium, and cytochalasin B on arachidonic acid-induced neutrophil aggregation
JT O'Flaherty
Inflammation 1980
Vitamin E modulates the lipoxygenation of arachidonic acid in leukocytes
EJ Goetzl
Nature 1980
Phospholipase A2 and Arachidonic Acid: a Common Link in the Generation of the Eosinophil Chemotactic Factor (ECF) from Human PMN by Various Stimuli
H Tesch, W Konig
Scandinavian Journal of Immunology 1980
The human eosinophil: roles in host defense and tissue injury
PF Weller, EJ Goetzl
The American Journal of Pathology 1980
Free radicals and inflammation: superoxide-dependent activation of a neutrophil chemotactic factor in plasma
WF Petrone, DK English, K Wong, JM McCord
Proceedings of the National Academy of Sciences 1980
Role of arachidonic acid in stimulation of hexose transport by human polymorphonuclear leukocytes
DA Bass, JT O'Flaherty, P Szejda, LR DeChatelet, CE McCall
Proceedings of the National Academy of Sciences 1980
Modulation of human neutrophil function by monohydroxy-eicosatetraenoic acids
EJ Goetzl, AR Brash, AI Tauber, JA Oates, WC Hubbard
Immunology 1980
A role for endogenous mono-hydroxy-eicosatetraenoic acids (HETEs) in the regulation of human neutrophil migration
EJ Goetzl
Immunology 1980
The lung mast cell: its physiology and potential relevance to defense of the lung
SI Wasserman
Environmental Health Perspectives 1980
Inhibition of human polymorphonuclear leukocyte chemotaxis by oxygenated sterol compounds
LI Gordon, J Bass, S Yachnin
Proceedings of the National Academy of Sciences 1980
Structural requirements for the activity of an immunologically generated lipid chemotactic factor
FH Valone, EJ Goetzl
Immunology 1980
Arachidonate metabolism via lipoxygenase and 12L-hydroperoxy-5,8,10,14-icosatetraenoic acid peroxidase sensitive to anti-inflammatory drugs
MI Siegel, RT McConnell, NA Porter, P Cuatrecasas
Proceedings of the National Academy of Sciences 1980
Alveolar macrophage lipoxygenase products of arachidonic acid: Isolation and recognition as the predominant constituents of the neutrophil chemotactic activity elaborated by alveolar macrophages
FH Valone, M Franklin, FF Sun, EJ Goetzl
Cellular Immunology 1980
Preparation and assay of monohydroxy-eicosatetraenoic acids
JM Boeynaems, AR Brash, JA Oates, WC Hubbard
Analytical Biochemistry 1980
Unique aspects of the modulation of human neutrophil function by 12-L-hydroperoxy-5,8,10,14-eicosatetraenoic acid
EJ Goetzl, HR Hill, RR Gorman
Prostaglandins 1980
Flavonoids and related compounds as inhibitors of arachidonic acid peroxidation
J Baumann, F Bruchhausen, G Wurm
Prostaglandins 1980
Modulation of human neutrophil and eosinophil polymorphonuclear leukocyte chemotaxis: An analytical review
FH Valone
Clinical Immunology and Immunopathology 1980
Inactivation of vascular prostacyclin synthetase by platelet lipoxygenase products
J Turk, A Wyche, P Needleman
Biochemical and Biophysical Research Communications 1980
An inhibitor of lipoxygenase inhibits histamine release from human basophils
G Marone, H Sven, LM Lichtenstein
Clinical Immunology and Immunopathology 1980
The development of a radioimmunoassay for 12-L-hydroxyeicosatetraenoic acid
L Levine, I Alam, H Gjika, TJ Carty, EJ Goetzl
Prostaglandins 1980
Mediators of Immediate Hypersensitivity Derived from Arachidonic Acid
EJ Goetzl
New England Journal of Medicine 1980
Aspirin-like drugs inhibit arachidonic acid metabolism via lipoxygenase and cyclo-oxygenase in rat neutrophils from carrageenan pleural exudates
MI Siegel, RT McConnell, NA Porter, JL Selph, JF Truax, R Vinegar, P Cuatrecasas
Biochemical and Biophysical Research Communications 1980
Preparation of [3H]-12-L-hydroxyeicosatetraenoic acid and its use in radioimmunoassay
JD Eskra, L Levine, TJ Carty
Prostaglandins and Medicine 1980
A new antiinflammatory compound, timegadine (N-cyclohexyl-N′′-p-methylquinolylN′-Z-thiazolylguanidine), which inhibits both prostaglandin and 12-hydroxyeicosatetraenoic acid (12-HETE) formation
I Ahnfelt-Rønne, E Arrigoni-Martelli
Biochemical Pharmacology 1980
Piroxicam, a structurally novel anti-inflammatory compound. Mode of prostaglandin synthesis inhibition
TJ Carty, JS Stevens, JG Lombardino, MJ Parry, MJ Randall
Prostaglandins 1980
Biochemistry and Metabolism
AJ Sbarra, RR Strauss
1980
Prostaglandins, Prostacyclin, and Thromboxanes Measurement
JM Boeynaems, AG Herman
1980
Modulation of polymorphonuclear leukocyte locomotion by synthetic amphiphiles: Effect of saturated fatty acid esters (C2–C18) of poly(ethyleneglycol) 6000
C Dahlgren, I Rundqvist, O Stendahl,
Cell Biochemistry and Biophysics 1980
Specific Inhibition of the Polymorphonuclear Leukocyte Chemotactic Response to Hydroxy-Fatty Acid Metabolites of Arachidonic Acid by Methyl Ester Derivatives
EJ Goetzl, FH Valone, VN Reinhold, RR Gorman
Journal of Clinical Investigation 1979
The effect of 5,8,11,14-eicosatetraynoic acid on lipid metabolism
LD Tobias, JG Hamilton
Lipids 1979
The relevance of neutrophil chemotactic factors to allergic disease
SI Wasserman, DM Center
Journal of Allergy and Clinical Immunology 1979
URTICARIA/ANGIOEDEMA A CONSIDERATION OF PATHOCENESIS AND CLINICAL MANIFESTATIONS
NA Soter, SI Wasserman
International Journal of Dermatology 1979
Serum Eosinophil Chemotactic Factor Levels in Patients with Bullous Pemphigoid, Drug Reactions and Atopic Eczema
BM Czarnetzki, KJ Kalveram, U Dierksmeier
Journal of Investigative Dermatology 1979
The aggregation of rat neutrophils by arachidonic acid: a possible bioassay for lipoxygenase activity
AW Ford-Hutchinson, MA Bray, MJ Smith
Journal of Pharmacy and Pharmacology 1979
INHIBITION OF PLATELET AGGREGATION AND THROMBOXANE SYNTHESIS BY ONION AND GARLIC
AN Makheja, JY Vanderhoek, JM Bailey
The Lancet 1979
RECRUITMENT TO PSYCHIATRY
WM Millar
The Lancet 1979
A possible role of arachidonic acid in human neutrophil aggregation and degranulation
JT O'Flaherty, HJ Showell, PA Ward, EL Becker
The American Journal of Pathology 1979
Neutrophil aggregation and degranulation. Effect of arachidonic acid
JT O'Flaherty, HJ Showell, EL Becker, PA Ward
The American Journal of Pathology 1979
Arachidonic acid metabolism in polymorphonuclear leukocytes: effects of ionophore A23187
P Borgeat, B Samuelsson
Proceedings of the National Academy of Sciences 1979
Chemotactic factor receptors of human PMN leucocytes. I. Effects on migration of labelling plasma membrane determinants with impermeant covalent reagents and inhibition of labelling by chemotactic factors
EJ Goetzl, KY Hoe
Immunology 1979
Generation and secretion of eosinophilotactic activity from human polymorphonuclear neutrophils by various mechanisms of cell activation
W König, N Frickhofen, H Tesch
Immunology 1979
Generation of unique mono-hydroxy-eicosatetraenoic acids from arachidonic acid by human neutrophils
EJ Goetzl, FF Sun
Journal of Experimental Medicine 1979
Inhibition of neutrophil chemotaxis in association with experimental angioedema in patients with cold urticaria: a model of chemotactic deactivation in vivo
DM Center, NA Soter, SI Wasserman, KF Austen
Clinical & Experimental Immunology 1979
Aspirin-like drugs interfere with arachidonate metabolism by inhibition of the 12-hydroperoxy-5,8,10,14-eicosatetraenoic acid peroxidase activity of the lipoxygenase pathway
MI Siegel, RT McConnell, P Cuatrecasas
Proceedings of the National Academy of Sciences 1979
The use of high pressure liquid chromatography (HPLC) for the separation of radiolabeled arachidonic acid and its metabolites produced by thrombin-treated human platelets
D Deykin, FA Russell, R Vaillancourt
Prostaglandins 1979
Prostaglandin formation in bacteria
E Gulbis, AM Marion, JE Dumont, E Schell-Frederick
Prostaglandins 1979
Biochemical and Clinical Aspects of Oxygen
S Charache
Biochemical and Clinical Aspects of Oxygen 1979
12-L-hydroxy-5,8,10,14-eicosatetraenoic acid, a chemotactic fatty acid, is incorporated into neutrophil phospholipids and triglyceride
WF Stenson, CW Parker
Prostaglandins 1979
A new approach to anti-inflammatory drugs
GA Higgs, RJ Flower, JR Vane
Biochemical Pharmacology 1979
Regulation of arachidonate metabolism via lipoxygenase and cyclo-oxygenase by 12-HPETE, the product of human platelet lipoxygenase
MI Siegel, RT McConnell, SL Abrahams, NA Porter, P Cuatrecasas
Biochemical and Biophysical Research Communications 1979
Stimulation of human T-lymphocyte chemokinesis by arachidonic acid
J McCarty, EJ Goetzl
Cellular Immunology 1979
Cellular, Molecular, and Clinical Aspects of Allergic Disorders
S Gupta, RA Good
1979
Function and Structure of the Immune System
W Müller-Ruchholtz, HK Müller-Hermelink
1979
Prostaglandins and Inflammation
KD Rainsford, AW Ford-Hutchinson
1979
Production of a Low Molecular Weight Eosinophil Polymorphonuclear Leukocyte Chemotactic Factor by Anaplastic Squamous Cell Carcinomas of Human Lung
EJ Goetzl, AH Tashjian, RH Rubin, KF Austen
Journal of Clinical Investigation 1978
Platelet responses in health and disease
MI Barnhart
Molecular and Cellular Biochemistry 1978
Platelets in the synovial space
MH Ginsberg, G Breth, JL Skosey
Arthritis & Rheumatism 1978
Generation and release of eosinophil chemotactic factor from human polymorphonuclear neutrophils by arachidonic acid
W König, H Tesch, N Frickhofen
European Journal of Immunology 1978
Motility of human polymorphonuclear leukocytes. Roles of hydroxy fatty acids, other lipids, and cations
WS Lynn, C Mukherjee
The American Journal of Pathology 1978
Preparation and Spectral Properties of 12-Hydroxyl Eicosatetraenoic Acid (HETE)
JC Mcgulre, RC Kelly, RR Gorman, FF Sun
Preparative Biochemistry 1978
Chemotactic activity of thromboxane B2, prostaglandins and their metabolites for polymorphonuclear leucocytes
EA Kitchen, JR Boot, W Dawson
Prostaglandins 1978
REGULATION OF EPIDERMAL PROLIFERATION AND DIFFERENTIATION IN PSORIASIS
JJ Voorhees
The Journal of Dermatology 1978
Leukocytes as Secretory Organs of Inflammation
G Weissmann
Hospital Practice 1978
GENERAL ASSEMBLY OF MEMBERS AT THE 7TH ANNUAL MEETING OF THE EUROPEAN SOCIETY FOR DERMATOLOGICAL RESEARCH
MW Greaves
Journal of Investigative Dermatology 1977
IN VIVO CHEMOTAXIS INDUCED BY POLYUNSATURATED FATTY ACIDS
NS Penneys, P Simon, VA Ziboh, J Schlossberg
Journal of Investigative Dermatology 1977
A particulate arachidonate lipoxygenase in human blood platelets
PP Ho, CP Walters, HR Sullivan
Biochemical and Biophysical Research Communications 1977
Mast cell-mediated reactions of host defense and tissue injury: The regulatory role of eosinophil polymorphonuclear leukocytes
EJ Goetzl
Inflammation 1977
Free Radicals in Biology
WA Pryor
Free Radicals in Biology 1976
Advances in Lipid Research
AM Scanu
Advances in Lipid Research 1965

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