Thrombolytic agents may be useful in acute pulmonary embolism, but their optimal dosage remains uncertain. We have examined the relative efficacy of heparin and different doses of streptokinase, either alone or in combination, in acute experimental pulmonary embolism. A standardized massive embolus of autologous blood clot incorporating canine [125I]-fibrinogen was given to 40 dogs; the degree of resolution after 24 h was quantitated by measuring the radioactivity in the lungs and was compared with detailed postmortem observations.
J. F. Cade, J. Hirsh, E. Regoeczi, M. Gent, M. R. Buchanan, D. M. Hynes
Title and authors | Publication | Year |
---|---|---|
Left Apical Pedunculated Thrombus with Normal Ventricular Function Mimicking an Intracardiac Tumor
R Jeganathan, A Ralph-Edwards |
Journal of Cardiac Surgery | 2011 |
Annual Reports in Medicinal Chemistry
JJ Liu, TW Lee |
Annual Reports in Medicinal Chemistry Volume 46 | 2011 |
Disintegration and reorganization of fibrin networks during tissue-type plasminogen activator-induced clot lysis
DA Meh, MW Mosesson, JP DiOrio, KR Siebenlist, I Hernandez, DL Amrani, L Stojanovich |
Blood Coagulation & Fibrinolysis | 2001 |
Atherosclerosis
EM MD, ST MD, EA MD, AW MD, ED MD |
The Annals of Thoracic Surgery | 1997 |
A Review of Common Approaches to Heparin Dosing
T Hodgman |
Journal of Pharmacy Practice | 1995 |
Enhanced Streptokinase-Induced Thrombolysis Using Heparin in a Rabbit Model
RL Kolts, HS Maki, ME Kuehner, RC Roberts, RD Sautter |
Journal of Investigative Surgery | 1989 |
Thrombolytic therapy
JF Cade |
Blood Reviews | 1989 |
Induced clot lysis by mini-dose injection of streptokinase in non-perfused arterial segments of rabbits
RL Kolts, HS Maki, ME Kuehner, RC Roberts, RD Sautter |
Thrombosis Research | 1989 |
Imaging of human thrombi in the rabbit jugular vein: I: Comparison of two fibrin-specific monoclonal antibodies
PM Tymkewycz, LJ Creighton, PS Gascoine, GD Zanelli, PM Webbon, PJ Gaffney |
Thrombosis Research | 1989 |
Treatment of Massive Acute Pulmonary Embolism
KV Leeper, J Popovich, BA Lesser, D Adams, JW Froelich, MW Burke, PC Shetty, JH Thrall, PD Stein |
Chest | 1988 |
Acute Pulmonary Thromboembolism Treated Successfully by Balloon Angioplasty—A Case Report
K Handa, Y Sasaki, A Kiyonaga, M Fujino, T Hiroki, K Arakawa |
Angiology | 1988 |
Acute and chronic pulmonary thromboembolism: current perspectives part viii: summaRy and references
A Ansari |
Clinical Cardiology | 1987 |
Usefulness of residual plasma fibrinogen after intravenous streptokinase for predicting delay or failure of reperfusion in acute myocardial infarction
AS Lew, B Cercek, H Hod, PK Shah, W Ganz |
The American Journal of Cardiology | 1986 |
Enhancement of thrombolysis with tissue-type plasminogen activator by pretreatment with heparin
B Cercek, AS Lew, H Hod, J Yano, NK Reddy, W Ganz |
Circulation | 1986 |
STUDIES ON THE MEDICAL TREATMENT OF DEEP VEIN THROMBOSIS
S Schulman |
Acta Medica Scandinavica | 1985 |
Pulmonary thromboembolic disease
WR Bell, JR Bartholomew |
Current Problems in Cardiology | 1985 |
Coagulative interventions during angiography
JJ Bookstein, KM Moser, C Hougie |
Cardiovascular and Interventional Radiology | 1982 |
Current status of pulmonary thromboembolic disease: Pathophysiology, diagnosis, prevention, and treatment
WR Bell, TL Simon |
American Heart Journal | 1982 |
Measurement of fibrinopeptide a in canine blood—An interim report
GD Wilner |
Thrombosis Research | 1979 |
Guidelines for thrombolytic therapy of deep-vein thrombosis
VJ Marder |
Progress in Cardiovascular Diseases | 1979 |
The Gordon Wilson lecture: function of blood platelets and their role in thrombosis
JF Mustard |
Transactions of the American Clinical and Climatological Association | 1976 |
Antithrombotic Drugs: Part II1
AS Gallus, J Hirsh |
Drugs | 1976 |
Thrombosis
JC Poole, JE French |
Journal of Atherosclerosis Research | 1961 |