Phospholipid Metabolism in the Initiation of Renal Compensatory Growth after Acute Reduction of Renal Mass

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Abstract

Membrane metabolism was studied during the initiation of compensatory growth after acute reduction in renal mass. The rate of [14C]choline incorporation into phospholipid in renal cortical slices was increased by 37% at 5 min of compensatory growth in mice. The rate increased to the maximal value of 68% by 20 min and remained there for 3 h. The rate then remained increased at 28-34% above normal for 2 days and returned to normal by the 6th day.

Authors

F. Gary Toback, Patricia D. Smith, Leah M. Lowenstein