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Melissa K. Cavaghan, … , David A. Ehrmann, Kenneth S. Polonsky
Published August 1, 2000
Citation Information: J Clin Invest. 2000;106(3):329-333. https://doi.org/10.1172/JCI10761.
Citation Information: J Clin Invest. 2000;106(3):329-333. https://doi.org/10.1172/JCI10761.
Abstract
Authors
Melissa K. Cavaghan, David A. Ehrmann, Kenneth S. Polonsky
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Citations to this article (278)
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Inhibition of the sodium glucose co-transporter-2: its beneficial action and potential combination therapy for type 2 diabetes mellitus
LH Chen, PS Leung |
Diabetes, Obesity and Metabolism | 2013 |
|
Beta-cell function and insulin sensitivity at various degrees of glucose tolerance in Chinese subjects
JD Lin, YL Chen, CH Hsu, CZ Wu, AT Hsieh, CH Hsieh, JB Chang, YJ Liang, D Pei |
Diabetes Research and Clinical Practice | 2013 |
|
Pharmacology of signaling pathways: In type 2 diabetes
D Meerza, I Naseem, J Ahmed |
Diabetes & Metabolic Syndrome: Clinical Research & Reviews | 2013 |
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Usefulness of the insulin tolerance test in patients with type 2 diabetes receiving insulin therapy
K Okita, H Iwahashi, J Kozawa, Y Okauchi, T Funahashi, A Imagawa, I Shimomura |
Journal of Diabetes Investigation | 2013 |
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Metabolic syndrome in hemodialysis patients as a risk factor for new-onset diabetes mellitus after renal transplant: a prospective observational study
J Bonet, A Martinez-Castelao, B Bayés |
Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy | 2013 |
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Quantification of β-cell insulin secretory function using a graded glucose infusion with C-peptide deconvolution in dysmetabolic, and diabetic cynomolgus monkeys
X Wang, BC Hansen, D Shi, Y Fang, F Du, B Wang, YM Chen, FM Gregoire, YX Wang |
Diabetology & metabolic syndrome | 2013 |
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Dose effect and mode of inheritance of diabetogenic gene on mouse chromosome 11
N Babaya, H Ueda, S Noso, Y Hiromine, K Nojima, M Itoi-Babaya, M Kobayashi, T Fujisawa, H Ikegami |
Journal of Diabetes Research | 2013 |
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Cardiometabolic risk factors among HIV patients on antiretroviral therapy
JN Kiage, DC Heimburger, CK Nyirenda, MF Wellons, S Bagchi, BH Chi, JR Koethe, DK Arnett, EK Kabagambe |
Lipids in Health and Disease | 2013 |
|
Platycodi radix saponin inhibits α-glucosidase in vitro and modulates hepatic glucose-regulating enzyme activities in C57BL/KsJ-db/db mice
JS Lee, MS Choi, KI Seo, J Lee, HI Lee, JH Lee, MJ Kim, MK Lee |
Archives of Pharmacal Research | 2013 |
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Prevention of Diabetes With Pioglitazone in ACT NOW: Physiologic Correlates
RA DeFronzo, D Tripathy, DC Schwenke, M Banerji, GA Bray, TA Buchanan, SC Clement, A Gastaldelli, RR Henry, AE Kitabchi, S Mudaliar, RE Ratner, FB Stentz, N Musi, PD Reaven |
Diabetes | 2013 |
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Pancreatic -Cell Response to Increased Metabolic Demand and to Pharmacologic Secretagogues Requires EPAC2A
WJ Song, P Mondal, Y Li, SE Lee, MA Hussain |
Diabetes | 2013 |
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Homeostasis model assessment of insulin resistance for evaluating insulin sensitivity in patients with type 2 diabetes on insulin therapy
K Okita, H Iwahashi, J Kozawa, Y Okauchi, T Funahashi, A Imagawa, I Shimomura |
Endocrine Journal | 2013 |
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Hepatitis C Virus Induced a Novel Apoptosis-Like Death of Pancreatic Beta Cells through a Caspase 3-Dependent Pathway
Q Wang, J Chen, Y Wang, X Han, X Chen |
PloS one | 2012 |
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Steam-Dried Ginseng Berry Fermented with Lactobacillus plantarum Controls the Increase of Blood Glucose and Body Weight in Type 2 Obese Diabetic <i>db</i>/<i>db</i> Mice
ST Kim, HB Kim, KH Lee, YR Choi, HJ Kim, IS Shin, YS Gyoung, SS Joo |
Journal of Agricultural and Food Chemistry | 2012 |
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Weight Loss in Obese Prepubertal Children: The Influence of Insulin Resistance
V Chiavaroli, C Giannini, E D’Adamo, T Giorgis, M Torello, N D’Orazio, S Sestili, F Chiarelli, A Mohn |
Endocrine Research | 2012 |
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Insulin Promotes Iron Uptake in Human Hepatic Cell by Regulating Transferrin Receptor-1 Transcription Mediated by Hypoxia Inducible Factor-1
S Biswas, N Tapryal, R Mukherjee, R Kumar, CK Mukhopadhyay |
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease | 2012 |
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Antidiabetic Effects of SGLT2-Selective Inhibitor Ipragliflozin in Streptozotocin^|^ndash;Nicotinamide-Induced Mildly Diabetic Mice
A Tahara, E Kurosaki, M Yokono, D Yamajuku, R Kihara, Y Hayashizaki, T Takasu, M Imamura, L Qun, H Tomiyama, Y Kobayashi, A Noda, M Sasamata, M Shibasaki |
Journal of Pharmacological Sciences | 2012 |
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Balanced pan-PPAR activator bezafibrate in combination with statin: comprehensive lipids control and diabetes prevention?
A Tenenbaum, EZ Fisman |
Cardiovascular Diabetology | 2012 |
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Hepatitis C Virus Induced a Novel Apoptosis-Like Death of Pancreatic Beta Cells through a Caspase 3-Dependent Pathway
Q Wang, J Chen, Y Wang, X Han, X Chen, R Jhaveri |
PloS one | 2012 |
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Animal Models in Diabetes Research
HG Joost, H Al-Hasani, A Schürmann |
2012 | |
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Application of Peptide-Based Prodrug Chemistry in Drug Development
A De |
2012 | |
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Insulin dynamics in obesity and diabetes
Susumu Seino, Tadao Shibasaki, Kohtaro Minami |
Journal of Clinical Investigation | 2011 |
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β-Cell failure in type 2 diabetes
G Leibowitz, N Kaiser, E Cerasi |
Journal of Diabetes Investigation | 2011 |
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Histone Deacetylases: the Biology and Clinical Implication
TP Yao, E Seto |
2011 | |
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Histone Deacetylases: the Biology and Clinical Implication
TP Yao, E Seto |
2011 | |
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Histone Deacetylases: the Biology and Clinical Implication
TP Yao, E Seto |
2011 | |
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Histone Deacetylases: the Biology and Clinical Implication
TP Yao, E Seto |
2011 | |
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Histone Deacetylases: the Biology and Clinical Implication
TP Yao, E Seto |
2011 | |
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Histone Deacetylases: the Biology and Clinical Implication
TP Yao, E Seto |
2011 | |
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Histone Deacetylases: the Biology and Clinical Implication
TP Yao, E Seto |
2011 | |
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Egr-1 decreases adipocyte insulin sensitivity by tilting PI3K/Akt and MAPK signal balance in mice
X Yu, N Shen, ML Zhang, FY Pan, C Wang, WP Jia, C Liu, Q Gao, X Gao, B Xue, CJ Li |
The EMBO Journal | 2011 |
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New-Onset Diabetes After Renal Transplantation: Diagnosis, Incidence, Risk Factors, Impact on Outcomes, and Novel Implications
Z Kaposztas, E Gyurus, BD Kahan |
Transplantation Proceedings | 2011 |
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Metabolic syndrome and cardiovascular risk in survivors after hematopoietic cell transplantation
KS Baker, E Chow, J Steinberger |
Bone Marrow Transplantation | 2011 |
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Clinical features of Japanese type 2 diabetics with insulinogenic index in normal range after treatment of glucotoxicity
H Iwahashi, E Fukuda-Akita, A Fukuda-Tokunaga, K Okita, Y Horikawa, A Imagawa, T Funahashi, I Shimomura, K Yamagata |
Diabetology International | 2011 |
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Exercise and Type 2 diabetes: the metabolic benefits and challenges
D Cooper, DJ O’Gorman |
Diabetes Management | 2011 |
|
Anti-diabetic Effects of Hemicentrotus pulcherrimus Shells on Non-obese Type 2 Diabetic Goto-Kakizaki Rats
KS Kim, DI Kim, AK Lim, SR Yoon, JO Kim, GD Lee |
Journal of the Korean Society of Food Science and Nutrition | 2011 |
|
Outcomes of Simultaneous Pancreas-Kidney Transplantation in Type 2 Diabetic Recipients
MS Sampaio, HT Kuo, S Bunnapradist |
Clinical journal of the American Society of Nephrology : CJASN | 2011 |
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Effects of metformin on oxidative stress, adenine nucleotides balance, and glucose-induced insulin release impaired by chronic free fatty acids exposure in rat pancreatic islets
S Piro, A M Rabuazzo, M Renis, F Purrello |
Journal of Endocrinological Investigation | 2011 |
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Burger's Medicinal Chemistry and Drug Discovery
S Bruno, L Ronda, S Faggiano, S Bettati, A Mozzarelli |
Burger's Medicinal Chemistry and Drug Discovery | 2010 |
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Insulin Requirement Profiles of Patients with Type 2 Diabetes After Achieving Stabilized Glycemic Control with Short-Term Continuous Subcutaneous Insulin Infusion
YH Noh, WJ Lee, KA Kim, I Lim, JH Lee, JH Lee, S Kim, SB Choi |
Diabetes Technology & Therapeutics | 2010 |
|
High-fat feeding and staphylococcus intermedius infection impair beta cell function and insulin sensitivity in mongrel dogs
E Slavov, IP Georgiev, P Dzhelebov, I Kanelov, M Andonova, TM Georgieva, S Dimitrova |
Veterinary Research Communications | 2010 |
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Insulin tolerance test predicts the effectiveness of insulin sensitizers in japanese type 2 diabetic patients
J Kozawa, H Iwahashi, K Okita, Y Okauchi, A Imagawa, I Shimomura |
Diabetes Therapy | 2010 |
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The Stunned β Cell: A Brief History
E Ferrannini |
Cell Metabolism | 2010 |
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Síndrome metabólico en el adolescente
ME de Adana |
Anales de Pediatría Continuada | 2010 |
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Comparative identification of Ca2+ channel expression in INS-1 and rat pancreatic beta cells
F Li, ZM Zhang |
World journal of gastroenterology : WJG | 2009 |
|
Emerging Concepts in the Pathophysiology of Type 2 Diabetes Mellitus
PN Surampudi, J John-Kalarickal, VA Fonseca |
Mount Sinai Journal of Medicine: A Journal of Translational and Personalized Medicine | 2009 |
|
Subjective socioeconomic status and presence of the metabolic syndrome in midlife community volunteers
SB Manuck, JE Phillips, PJ Gianaros, JD Flory, MF Muldoon |
Psychosomatic medicine | 2009 |
|
Antidiabetic effects of dipeptidyl peptidase–IV inhibitors and sulfonylureas in streptozotocin-nicotinamide–induced mildly diabetic mice
A Matsuyama-Yokono, A Tahara, R Nakano, Y Someya, K Shiraki, M Hayakawa, M Shibasaki |
Metabolism | 2009 |
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Effects of the combination of dipeptidyl peptidase-IV inhibitor ASP8497 and antidiabetic drugs in streptozotocin-nicotinamide-induced mildly diabetic mice
A Tahara, A Matsuyama-Yokono, R Nakano, Y Someya, M Hayakawa, M Shibasaki |
European Journal of Pharmacology | 2009 |
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Balancing needs and means: the dilemma of the beta-cell in the modern world
G Leibowitz, N Kaiser, E Cerasi |
Diabetes, Obesity and Metabolism | 2009 |
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Cloning, expression, and pharmacological characterization of the GPR120 free fatty acid receptor from cynomolgus monkey: Comparison with human GPR120 splice variants
K Moore, Q Zhang, N Murgolo, T Hosted, R Duffy |
Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology | 2009 |
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Antihyperglycemic effects of ASP8497 in streptozotocin-nicotinamide induced diabetic rats: comparison with other dipeptidyl peptidase-IV inhibitors
A Tahara, A Matsuyama-Yokono, R Nakano, Y Someya, M Hayakawa, M Shibasaki |
Pharmacological Reports | 2009 |
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Impact of Incretin Therapy on Islet Dysfunction: An Underlying Defect in the Pathophysiology of Type 2 Diabetes
JB McGill |
Postgraduate Medicine | 2009 |
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Comparative identification of Ca 2+ channel expression in INS-1 and rat pancreatic β cells
F Li, ZM Zhang |
World journal of gastroenterology : WJG | 2009 |
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Chronic insulin treatment causes insulin resistance in 3T3-L1 adipocytes through oxidative stress
X Ge, Q Yu, W Qi, X Shi, Q Zhai |
Free Radical Research | 2008 |
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Beneficial Effect of Chungkukjang on Regulating Blood Glucose and Pancreaticβ-Cell Functions in C75BL/KsJ-db/dbMice
DJ Kim, YJ Jeong, JH Kwon, KD Moon, HJ Kim, SM Jeon, MK Lee, YB Park, MS Choi |
Journal of Medicinal Food | 2008 |
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Corosolic acid stimulates glucose uptake via enhancing insulin receptor phosphorylation
L Shi, W Zhang, YY Zhou, YN Zhang, JY Li, LH Hu, J Li |
European Journal of Pharmacology | 2008 |
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Independent measures of insulin secretion and insulin sensitivity during the same test: the glucagon–insulin tolerance test
M Dorkhan, D Tripathy, G Malm, H Asgharian, T Tuomi, L Groop |
Journal of Internal Medicine | 2008 |
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Preserving insulin secretion in Type 2 diabetes mellitus
J Tibaldi |
Expert Review of Endocrinology & Metabolism | 2008 |
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Topiramate and Type 2 diabetes: an old wine in a new bottle
V Khanna, S Arumugam, S Roy, S Mittra, VS Bansal |
Expert Opinion on Therapeutic Targets | 2008 |
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Increased β-Cell Apoptosis and Impaired Insulin Signaling Pathway Contributes to the Onset of Diabetes in OLETF Rats
J Zhao, N Zhang, M He, Z Yang, W Tong, Q Wang, R Hu |
Cellular Physiology and Biochemistry | 2008 |
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Gastrointestinal surgery as treatment for type 2 diabetes
TA Moo, F Rubino |
Current Opinion in Endocrinology, Diabetes and Obesity | 2008 |
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Incidence of Type 2 Diabetes Mellitus and Glucose Abnormalities in Patients With Chronic Hepatitis C Infection by Response to Treatment: Results of a Cohort Study
C Giordanino, E Bugianesi, A Smedile, A Ciancio, ML Abate, A Olivero, R Pellicano, M Cassader, R Gambino, S Bo, G Ciccone, M Rizzetto, G Saracco |
The American Journal of Gastroenterology | 2008 |
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Effect of curcumin supplementation on blood glucose, plasma insulin, and glucose homeostasis related enzyme activities in diabeticdb/dbmice
KI Seo, MS Choi, UJ Jung, HJ Kim, J Yeo, SM Jeon, MK Lee |
Molecular Nutrition & Food Research | 2008 |
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Potential Hypoglycemic Effect of an Ethanol Extract ofGynostemma pentaphyllumin C57BL/KsJ-db/dbMice
J Yeo, YJ Kang, SM Jeon, UJ Jung, MK Lee, H Song, MS Choi |
Journal of Medicinal Food | 2008 |
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Lipidomics: a new window to biomedical frontiers
M Orešič, VA Hänninen, A Vidal-Puig |
Trends in Biotechnology | 2008 |
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Can Newer Therapies Delay the Progression of Type 2 Diabetes Mellitus?
ES Horton |
Endocrine Practice | 2008 |
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Pre-teen insulin resistance predicts weight gain, impaired fasting glucose, and type 2 diabetes at age 18–19 y: a 10-y prospective study of black and white girls
JA Morrison, CJ Glueck, PS Horn, GB Schreiber, P Wang |
The American journal of clinical nutrition | 2008 |
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Type 2 Diabetes Mellitus
MN Feinglos, MA Bethel |
2008 | |
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Biochemical Aspects, Laboratory Diagnosis and Follow-Up of High Blood Cholesterol: NCEP ATP III Guidelines
S Jovičić |
Journal of Medical Biochemistry | 2008 |
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Disease, Diagnoses, and Dollars
RM Kaplan |
2008 | |
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Comparative Proteome Analysis of Neural Retinas from Type 2 Diabetic Rats by Two-dimensional Electrophoresis
YD Wang, JD Wu, ZL Jiang, Y Wang, XH Wang, C Liu, MQ Tong |
Current Eye Research | 2007 |
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Inhibition of PKCɛ Improves Glucose-Stimulated Insulin Secretion and Reduces Insulin Clearance
C Schmitz-Peiffer, DR Laybutt, JG Burchfield, E Gurisik, S Narasimhan, CJ Mitchell, DJ Pedersen, U Braun, GJ Cooney, M Leitges, TJ Biden |
Cell Metabolism | 2007 |
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Insulin Secretion Is Increased in Pancreatic Islets of Neuropeptide Y-Deficient Mice
Y Imai, HR Patel, EJ Hawkins, NM Doliba, FM Matschinsky, RS Ahima |
Endocrinology | 2007 |
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Involvement of the PA28γ-Dependent Pathway in Insulin Resistance Induced by Hepatitis C Virus Core Protein
H Miyamoto, K Moriishi, K Moriya, S Murata, K Tanaka, T Suzuki, T Miyamura, K Koike, Y Matsuura |
Journal of virology | 2007 |
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Gen-Umwelt-Interaktion in Pathogenese und Prävention des Diabetes mellitus Typ 2
A Fritsche, C Thamer, N Stefan, HU Häring |
Der Internist | 2007 |
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Fatty acid receptors as new therapeutic targets for diabetes
GV Rayasam, VK Tulasi, JA Davis, VS Bansal |
Expert Opinion on Therapeutic Targets | 2007 |
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Design, synthesis, and biological evaluation of substituted-N-(thieno[2,3-b]pyridin-3-yl)-guanidines, N-(1H-pyrrolo[2,3-b]pyridin-3-yl)-guanidines, and N-(1H-indol-3-yl)-guanidines
RH Bahekar, MR Jain, A Goel, DN Patel, VM Prajapati, AA Gupta, PA Jadav, PR Patel |
Bioorganic & Medicinal Chemistry | 2007 |
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Combination of dipeptidylpeptidase IV inhibitor and low dose thiazolidinedione: Preclinical efficacy and safety in db/db mice
S Roy, V Khanna, S Mittra, A Dhar, S Singh, DC Mahajan, P Priyadarsiny, JA Davis, J Sattigeri, KS Saini, VS Bansal |
Life Sciences | 2007 |
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Correlation between white blood cell count and metabolic syndrome in adolescence
CH Hsieh, D Pei, SW Kuo, CY Chen, SL Tsai, CL Lai, CH Lee, CZ Wu, YJ Hung, MC Hsieh |
Pediatrics International | 2007 |
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Long-term effect of bezafibrate on pancreatic beta-cell function and insulin resistance in patients with diabetes
H Tenenbaum, S Behar, V Boyko, Y Adler, EZ Fisman, D Tanne, M Lapidot, E Schwammenthal, M Feinberg, Z Matas, M Motro, A Tenenbaum |
Atherosclerosis | 2007 |
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Cirurgia gastrointestinal no tratamento da diabete tipo 2
AC de Freitas |
ABCD. Arquivos Brasileiros de Cirurgia Digestiva (São Paulo) | 2007 |
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Mecanismos cirúrgicos de controle do diabetes mellitus tipo 2 após cirurgia bariátrica
MV de Martins, AA de Souza |
Revista do Colégio Brasileiro de Cirurgiões | 2007 |
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β-Cell “rest” accompanies reduced first-pass hepatic insulin extraction in the insulin-resistant, fat-fed canine model
SP Kim, M Ellmerer, EL Kirkman, RN Bergman |
American journal of physiology. Endocrinology and metabolism | 2007 |
|
Impact of Family History of Diabetes and Ethnicity on β-Cell Function in Obese, Glucose-Tolerant Individuals
N Rasouli, HJ Spencer, AA Rashidi, SC Elbein |
The Journal of clinical endocrinology and metabolism | 2007 |
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Insulin resistance and atherosclerosis
CF Semenkovich |
Journal of Clinical Investigation | 2006 |
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Characterization of hearing loss in aged type II diabetics
ST Frisina, F Mapes, SH Kim, DR Frisina, RD Frisina |
Hearing Research | 2006 |
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Assessing progression to impaired glucose tolerance and type�2 diabetes mellitus
F Guerrero-Romero, M Rodríguez-Morán |
European Journal of Clinical Investigation | 2006 |
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Intracellular sodium increase and susceptibility to ischaemia in hearts from type 2 diabetic db/db mice
R Anzawa, M Bernard, S Tamareille, D Baetz, S Confort-Gouny, JP Gascard, P Cozzone, D Feuvray |
Diabetologia | 2006 |
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Salicornia herbacea prevents high fat diet-induced hyperglycemia and hyperlipidemia in ICR mice
SH Park, SK Ko, JG Choi, SH Chung |
Archives of Pharmacal Research | 2006 |
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Exogenous nitric oxide inhibits IRS-1 expression in rat hepatocytes and skeletal myocytes
S Badal, PD Brown, D Ragoobirsingh |
Journal of Biomedical Science | 2006 |
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Genistein and daidzein modulate hepatic glucose and lipid regulating enzyme activities in C57BL/KsJ-db/db mice
SA Park, MS Choi, SY Cho, JS Seo, UJ Jung, MJ Kim, MK Sung, YB Park, MK Lee |
Life Sciences | 2006 |
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Bariatric surgery: effects on glucose homeostasis
F Rubino |
Current Opinion in Clinical Nutrition and Metabolic Care | 2006 |
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Dental Management of Patients with Diabetes
SJ McKenna |
Dental clinics of North America | 2006 |
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Fatty acid metabolism is enhanced in type 2 diabetic hearts
AN Carley, DL Severson |
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids | 2005 |
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Effects of Short-Term Experimental Insulin Resistance and Family History of Diabetes on Pancreatic β-Cell Function in Nondiabetic Individuals
N Rasouli, T Hale, SE Kahn, HJ Spencer, SC Elbein |
The Journal of clinical endocrinology and metabolism | 2005 |
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The HNF-1 target Collectrin controls insulin exocytosis by SNARE complex formation
K Fukui, Q Yang, Y Cao, N Takahashi, H Hatakeyama, H Wang, J Wada, Y Zhang, L Marselli, T Nammo, K Yoneda, M Onishi, S Higashiyama, Y Matsuzawa, FJ Gonzalez, GC Weir, H Kasai, I Shimomura, J Miyagawa, CB Wollheim, K Yamagata |
Cell Metabolism | 2005 |
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K-value and low insulin secretion in a non-obese white population: predicted glucose tolerance after 25 years
M Alvarsson, A Wajngot, E Cerasi, S Efendic |
Diabetologia | 2005 |
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Adiponectin and beta cell dysfunction in gestational diabetes: pathophysiological implications
R Retnakaran, AJ Hanley, N Raif, CR Hirning, PW Connelly, M Sermer, SE Kahn, B Zinman |
Diabetologia | 2005 |
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Role of impaired insulin secretion and insulin resistance in the pathogenesis of type 2 diabetes mellitus
E Szoke, JE Gerich |
Comprehensive Therapy | 2005 |
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Genetic and Genomic Studies of the BTBR ob/ob Mouse Model of Type 2 Diabetes
SM Clee, ST Nadler, AD Attie |
American Journal of Therapeutics | 2005 |
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A Novel Model of Obesity-Related Diabetes: Introgression of the Leprfa Allele of the Zucker Fatty Rat into Nonobese Spontaneously Diabetic Torii (SDT) Rats
T MASUYAMA, Y KATSUDA, M SHINOHARA |
Experimental Animals | 2005 |
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Euonymus alatus prevents the hyperglycemia and hyperlipidemia induced by high-fat diet in ICR mice
SH Park, SK Ko, SH Chung |
Journal of Ethnopharmacology | 2005 |
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Pathogenesis of Type 2 Diabetes Mellitus
JL Leahy |
Archives of Medical Research | 2005 |
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Temas de actualidad en cardiología preventiva: el síndrome metabólico
AR Ligorit, IJ Montero, JA Lenguas, EA Ezquerra, M Laclaustra, M León, A Cordero, A Grima |
Revista Española de Cardiología Suplementos | 2005 |
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Matrix metalloproteinases contribute to insulin insufficiency in Zucker diabetic fatty rats
Yun-Ping Zhou, Azadeh Madjidi, Maria E Wilson, David A Nothhelfer, John H Johnson, John F Palma, Anthony Schweitzer, Charles Burant, John E Blume, Jeffrey D Johnson |
Diabetes | 2005 |
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Correlations Between White Blood Cell Count and Metabolic Syndrome in Middle-Age Taiwanese
SK Chuo, JC Li, WC Tsai, DA Wu, SW Kuo, D Pei, SP Chen, DC Shen |
Endocrine Research | 2005 |
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An overview of the central control of weight regulation and the effect of antipsychotic medication
S Tighe, T Dinan |
Journal of Psychopharmacology (Oxford, England) | 2005 |
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Structural and functional analysis of pancreatic islets preserved by pioglitazone in db/db mice
F Kawasaki, M Matsuda, Y Kanda, H Inoue, K Kaku |
American journal of physiology. Endocrinology and metabolism | 2005 |
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Dietary carbohydrate modification enhances insulin secretion in persons with the metabolic syndrome
DE Laaksonen, LK Toppinen, KS Juntunen, K Autio, KH Liukkonen, KS Poutanen, L Niskanen, HM Mykkänen |
The American journal of clinical nutrition | 2005 |
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Comprehensive Analysis of Human Pancreatic Islet Expression Profile by Serial Analysis of Gene Expression
Hiroshi Inoue, Corentin Cras-Méneur, Yiyong Zhou, Mitsuru Ohsugi, Ernesto Bernal-Mizrachi, Deana Pape, Sandra W.Clifton, M. Alan Permutt |
Diabetologia | 2004 |
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Gender-dependent attenuation of cardiac potassium currents in type 2 diabetic db/db mice: Attenuation of cardiac K + currents in diabetic mice
Y Shimoni, M Chuang, ED Abel, DL Severson |
The Journal of Physiology | 2004 |
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Gut peptides in the treatment of diabetes mellitus
TP Vahl, DA D’Alessio |
Expert Opinion on Investigational Drugs | 2004 |
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Hepatitis C virus infection and diabetes: direct involvement of the virus in the development of insulin resistance
Y Shintani, H Fujie, H Miyoshi, T Tsutsumi, K Tsukamoto, S Kimura, K Moriya, K Koike |
Gastroenterology | 2004 |
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Chronological characterization of diabetes development in male Spontaneously Diabetic Torii rats
T Masuyama, K Komeda, A Hara, M Noda, M Shinohara, T Oikawa, Y Kanazawa, K Taniguchi |
Biochemical and Biophysical Research Communications | 2004 |
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Insulin resistance syndrome: a potent culprit in cardiovascular disease
AM Coulston, V Peragallo-Dittko |
Journal of the American Dietetic Association | 2004 |
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Novel strategies for the pharmacological management of type 2 diabetes
A Nourparvar, A Bulotta, UD Mario, R Perfetti |
Trends in Pharmacological Sciences | 2004 |
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Roles for bone-marrow-derived cells in β-cell maintenance
JS Tessem, J DeGregori |
Trends in Molecular Medicine | 2004 |
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Wild ginseng prevents the onset of high-fat diet induced hyperglycemia and obesity in icr mice
SN Yun, SJ Moon, SK Ko, BO Im, SH Chung |
Archives of Pharmacal Research | 2004 |
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MATURITY-ONSET DIABETES OF THE YOUNG WITH END-STAGE NEPHROPATHY: A NEW INDICATION FOR SIMULTANEOUS PANCREAS AND KIDNEY TRANSPLANTATION?
F Saudek, Š Průhová, P Bouček, J Lebl, M Adamec, J Ek, O Pedersen, T Hansen |
Transplantation | 2004 |
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Diabetes Due to a Progressive Defect in -Cell Mass in Rats Transgenic for Human Islet Amyloid Polypeptide (HIP Rat): A New Model for Type 2 Diabetes
AE Butler, J Jang, T Gurlo, MD Carty, WC Soeller, PC Butler |
Diabetes | 2004 |
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Potential Role of Peroxisome Proliferator-Activated Receptor- in the Modulation of Glucose-Stimulated Insulin Secretion
MC Sugden, MJ Holness |
Diabetes | 2004 |
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Acute -3 Fatty Acid Enrichment Selectively Reverses High-Saturated Fat Feeding-Induced Insulin Hypersecretion But Does Not Improve Peripheral Insulin Resistance
MJ Holness, ND Smith, GK Greenwood, MC Sugden |
Diabetes | 2004 |
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Structural and Functional Abnormalities in the Islets Isolated From Type 2 Diabetic Subjects
S Deng, M Vatamaniuk, X Huang, N Doliba, MM Lian, A Frank, E Velidedeoglu, NM Desai, B Koeberlein, B Wolf, CF Barker, A Naji, FM Matschinsky, JF Markmann |
Diabetes | 2004 |
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Impaired -cell compensation to dexamethasone-induced hyperglycemia in women with polycystic ovary syndrome
DA Ehrmann |
American journal of physiology. Endocrinology and metabolism | 2004 |
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Metabolic risk in early childhood: the EarlyBird Study
TJ Wilkin, LD Voss, BS Metcalf, K Mallam, AN Jeffery, S Alba, MJ Murphy |
International Journal of Obesity | 2004 |
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International Textbook of Diabetes Mellitus
RA DeFronzo, L Mandarino, E Ferrannini |
International Textbook of Diabetes Mellitus | 2003 |
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Prediabetes mellitus and its links to atherosclerosis
D Kramer, A Raji, J Plutzky |
Current Diabetes Reports | 2003 |
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The insulin resistance syndrome and coronary artery disease
DM Kendall, BE Sobel, AM Coulston, AL Harmel, BK McLean, V Peragallo-Dittko, JB Buse, VA Fonseca, JO Hill, RW Nesto, XF Sunyer |
Coronary Artery Disease | 2003 |
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Current Opinion in Endocrinology & Diabetes | 2003 |
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Clinical features of diabetes mellitus with the mitochondrial DNA 3243 (A–G) mutation in Japanese: Maternal inheritance and mitochondria-related complications
S Suzuki, Y Oka, T Kadowaki, A Kanatsuka, T Kuzuya, M Kobayashi, T Sanke, Y Seino, K Nanjo |
Diabetes Research and Clinical Practice | 2003 |
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Contributions of Insulin-Resistance and Insulin-Secretory Defects to the Pathogenesis of Type 2 Diabetes Mellitus
JE Gerich |
Mayo Clinic Proceedings | 2003 |
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Age-Dependent Changes in Metabolism, Contractile Function, and Ischemic Sensitivity in Hearts From db/db Mice
E Aasum, AD Hafstad, DL Severson, TS Larsen |
Diabetes | 2003 |
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Insulin Resistant State in Type 2 Diabetes Is Related to Advanced Autonomic Neuropathy
S Nakano, M Kitazawa, T Ito, H Hatakeyama, M Nishizawa, A Nakagawa, T Kigoshi, K Uchida |
Clinical and Experimental Hypertension | 2003 |
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Peroxisome proliferator activated receptor gamma and its activation in the treatment of insulin resistance and atherosclerosis: issues and opportunities:
J Beckman, A Raji, J Plutzky |
Current Opinion in Cardiology | 2003 |
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The Transcription Factor SREBP-1c Is Instrumental in the Development of β-Cell Dysfunction
H Wang, P Maechler, PA Antinozzi, L Herrero, KA Hagenfeldt-Johansson, A Björklund, CB Wollheim |
The Journal of biological chemistry | 2003 |
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Atherosclerosis, Hypertension and Diabetes
GN Pierce, M Nagano, P Zahradka, NS Dhalla |
2003 | |
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Poor Lipid Control in Type-2 Diabetics With and Without Ischemic Heart Disease
DH Akbar, AA Al-Gamdi, NA Hejazi |
Endocrine | 2003 |
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FLIP switches Fas-mediated glucose signaling in human pancreatic beta cells from apoptosis to cell replication
K Maedler, A Fontana, F Ris, P Sergeev, C Toso, J Oberholzer, R Lehmann, F Bachmann, A Tasinato, GA Spinas, PA Halban, MY Donath |
Proceedings of the National Academy of Sciences | 2002 |
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Identifying the links between obesity, insulin resistance and beta-cell function: potential role of adipocyte-derived cytokines in the pathogenesis of type 2 diabetes
AS Greenberg, ML McDaniel |
European Journal of Clinical Investigation | 2002 |
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Pleiotropic effects of fatty acids on pancreatic ?-cells
EP Haber, HM Ximenes, J Proc�pio, CR Carvalho, R Curi, AR Carpinelli |
Journal of Cellular Physiology | 2002 |
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Redefining the clinical management of type 2 diabetes: matching therapy to pathophysiology
JE Gerich |
European Journal of Clinical Investigation | 2002 |
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Potential of surgery for curing type 2 diabetes mellitus
F Rubino, M Gagner |
Annals of Surgery | 2002 |
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Obesity and gender differences in the risk of type 2 diabetes mellitus in Uganda
D Lasky, E Becerra, W Boto, M Otim, J Ntambi |
Nutrition | 2002 |
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Potential of Surgery for Curing Type 2 Diabetes Mellitus:
F Rubino, M Gagner |
Annals of Surgery | 2002 |
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Insulin Secretory Function Is Impaired in Isolated Human Islets Carrying the Gly972->Arg IRS-1 Polymorphism
P Marchetti, R Lupi, M Federici, L Marselli, M Masini, U Boggi, SD Guerra, G Patane, S Piro, M Anello, E Bergamini, F Purrello, R Lauro, F Mosca, G Sesti, SD Prato |
Diabetes | 2002 |
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Glucagon Replacement via Micro-Osmotic Pump Corrects Hypoglycemia and -Cell Hyperplasia in Prohormone Convertase 2 Knockout Mice
GC Webb, MS Akbar, C Zhao, HH Swift, DF Steiner |
Diabetes | 2002 |
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Role of ATP Production and Uncoupling Protein-2 in the Insulin Secretory Defect Induced by Chronic Exposure to High Glucose or Free Fatty Acids and Effects of Peroxisome Proliferator-Activated Receptor- Inhibition
G Patane, M Anello, S Piro, R Vigneri, F Purrello, AM Rabuazzo |
Diabetes | 2002 |
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Increased Glucose Sensitivity of Stimulus-Secretion Coupling in Islets From Psammomys obesus After Diet Induction of Diabetes
JA Pertusa, R Nesher, N Kaiser, E Cerasi, JC Henquin, JC Jonas |
Diabetes | 2002 |
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Echocardiographic assessment of cardiac function in diabetic db/db and transgenic db/db -hGLUT4 mice
LM Semeniuk, AJ Kryski, DL Severson |
American journal of physiology. Heart and circulatory physiology | 2002 |
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Survival, liver failure, and hepatocellular carcinoma in obesity-related cryptogenic cirrhosis
V Ratziu, L Bonyhay, VD Martino, F Charlotte, L Cavallaro, MH Sayegh-Tainturier, P Giral, A Grimaldi, P Opolon, T Poynard |
Hepatology | 2002 |
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Impaired glucose tolerance and metformin: clinical and mechanistic aspects
LS Hermann, N Wiernsperger |
The British Journal of Diabetes & Vascular Disease | 2002 |
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Diabetes mellitus and genetically programmed defects in β-cell function
GI Bell, KS Polonsky |
Nature | 2001 |
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Journal of Cardiovascular Risk
S Kumbasar, I Dincer, F Ertas, S Gulec, C Erol, O Akyurek, M Kilickap, D Oral, E Sipahi, Y Laleli |
Journal of Cardiovascular Risk | 2001 |
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Neurohumoral regulation of body weight gain
SU Devaskar |
Pediatric Diabetes | 2001 |
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New Perspectives into the Molecular Pathogenesis and Treatment of Type 2 Diabetes
AR Saltiel |
Cell | 2001 |
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Familial resemblance for glucose and insulin metabolism indices derived from an intravenous glucose tolerance test in Blacks and Whites of the HERITAGE Family Study: Heritability of glucose homeostasis from IVGTT
Y Hong, SJ Weisnagel, T Rice, G Sun, SA Mandel, C Gu, T Rankinen, J Gagnon, AS Leon, JS Skinner, JH Wilmore, RN Bergman, C Bouchard, DC Rao |
Clinical Genetics | 2001 |
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Insights into insulin resistance and type 2 diabetes from knockout mouse models
T Kadowaki |
Journal of Clinical Investigation | 2000 |
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Effect of glucose on initiation and elongation rates in isolated rat pancreatic islets
HP Harding, H Zeng, Y Zhang, R Jungries, P Chung, H Plesken, DD Sabatini, D Ron |
The Journal of biological chemistry | 1974 |
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