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Citations to this article

Hyperlipidemia in Coronary Heart Disease II. GENETIC ANALYSIS OF LIPID LEVELS IN 176 FAMILIES AND DELINEATION OF A NEW INHERITED DISORDER, COMBINED HYPERLIPIDEMIA
Joseph L. Goldstein, … , Edwin L. Bierman, Arno G. Motulsky
Joseph L. Goldstein, … , Edwin L. Bierman, Arno G. Motulsky
Published July 1, 1973
Citation Information: J Clin Invest. 1973;52(7):1544-1568. https://doi.org/10.1172/JCI107332.
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Research Article Article has an altmetric score of 19

Hyperlipidemia in Coronary Heart Disease II. GENETIC ANALYSIS OF LIPID LEVELS IN 176 FAMILIES AND DELINEATION OF A NEW INHERITED DISORDER, COMBINED HYPERLIPIDEMIA

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Abstract

To assess the genetics of hyperlipidemia in coronary heart disease, family studies were carried out in 2520 relatives and spouses of 176 survivors of myocardial infarction, including 149 hyperlipidemic and 27 normolipidemic individuals. The distribution of fasting plasma cholesterol and triglyceride values in relatives, together with segregation analyses, suggested the presence of five distinct lipid disorders. Three of these—familial hypercholesterolemia, familial hypertriglyceridemia, and familial combined hyperlipidemia—appeared to represent dominant expression of three different autosomal genes, occurring in about 20% of survivors below 60 yr of age and 7% of all older survivors. Two other disorders—polygenic hypercholesterolemia and sporadic hypertriglyceridemia—each affected about 6% of survivors in both age groups.

Authors

Joseph L. Goldstein, Helmut G. Schrott, William R. Hazzard, Edwin L. Bierman, Arno G. Motulsky

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MD Miedema, SS Virani
The American Journal of Cardiology 2016
Translational Research for Improving the Care of Familial Hypercholesterolemia: The “Ten Countries Study” and Beyond
GF Watts, PY Ding, P George, MS Hagger, M Hu, J Lin, KL Khoo, AD Marais, T Miida, HM Nawawi, J Pang, JE Park, LB Gonzalez-Santos, TC Su, TH Truong, RD Santos, H Soran, S Yamashita, B Tomlinson
Journal of Atherosclerosis and Thrombosis 2016
Antidiabetic, antihyperlipidemic and antioxidant properties of ethanol extract of Grewia asiatica Linn. bark in alloxan-induced diabetic rats
NA Khatune, BM Rahman, RK Barman, MI Wahed
BMC complementary and alternative medicine 2016
Efficacy and safety of the cholesteryl ester transfer protein inhibitor anacetrapib in Japanese patients with heterozygous familial hypercholesterolemia
H Arai, T Teramoto, H Daida, K Ikewaki, Y Maeda, M Nakagomi, M Shirakawa, T Kakikawa, H Numaguchi, AO Johnson-Levonas, S Vaidya, RO Blaustein
Atherosclerosis 2016
Diagnosis and treatment of high density lipoprotein deficiency
EJ Schaefer, P Anthanont, MR Diffenderfer, E Polisecki, BF Asztalos
Progress in Cardiovascular Diseases 2016
Familial Hypercholesterolaemia in the Era of Genetic Testing
DP Hughes, A Viljoen, AS Wierzbicki
Current Cardiology Reports 2016
The Contribution of GWAS Loci in Familial Dyslipidemias
P Ripatti, JT Rämö, S Söderlund, I Surakka, N Matikainen, M Pirinen, P Pajukanta, AP Sarin, SK Service, PP Laurila, C Ehnholm, V Salomaa, RK Wilson, A Palotie, NB Freimer, MR Taskinen, S Ripatti, G Gibson
PLoS genetics 2016
Rapid identification of familial hypercholesterolemia from electronic health records: The SEARCH study
MS Safarova, H Liu, IJ Kullo
Journal of Clinical Lipidology 2016
Leveraging Human Genetics to Guide Drug Target Discovery
NO Stitziel, S Kathiresan
Trends in Cardiovascular Medicine 2016
Familial combined hyperlipidemia and hyperlipoprotein(a) as phenotypic mimics of familial hypercholesterolemia: Frequencies, associations and predictions
KL Ellis, J Pang, DC Chan, AJ Hooper, DA Bell, JR Burnett, GF Watts
Journal of Clinical Lipidology 2016
Old challenges and new opportunities in the clinical management of heterozygous familial hypercholesterolemia (HeFH): The promises of PCSK9 inhibitors
M Arca
Atherosclerosis 2016
Screening for genetic mutations in children and adolescents with dyslipidemia: importance of early identification and implications of missed diagnoses
DP Wilson, A la Torre, A Brautbar, L Hamilton
Expert Opinion on Orphan Drugs 2016
Inborn Metabolic Diseases
JM Saudubray, MR Baumgartner, J Walter
Inborn Metabolic Diseases 2016
Identification of the Functional Variant(s) that Explain the Low-Density Lipoprotein Receptor (LDLR) GWAS SNP rs6511720 Association with Lower LDL-C and Risk of CHD
RH Fairoozy, J White, J Palmen, AZ Kalea, SE Humphries, NH Bishopric
PloS one 2016
Triglyceride Treatment in the Age of Cholesterol Reduction
N Agrawal, PF Corradi, N Gumaste, IJ Goldberg
Progress in Cardiovascular Diseases 2016
Diagnosis and treatment of high density lipoprotein deficiency
EJ Schaefer, P Anthanont, MR Diffenderfer, E Polisecki, BF Asztalos
Progress in Cardiovascular Diseases 2016
Genetic identification of familial hypercholesterolemia within a single U.S. health care system
NS Abul-Husn, K Manickam, LK Jones, EA Wright, DN Hartzel, C Gonzaga-Jauregui, C ODushlaine, JB Leader, HL Kirchner, DA Lindbuchler, ML Barr, MA Giovanni, MD Ritchie, JD Overton, JG Reid, RP Metpally, AH Wardeh, IB Borecki, GD Yancopoulos, A Baras, AR Shuldiner, O Gottesman, DH Ledbetter, DJ Carey, FE Dewey, MF Murray
Science 2016
Transcription factor 7-like 2 (TCF7L2) Gene Polymorphism rs7903146 is Associated with Lipid Profile and Risk of Cardiovascular Disease in Metabolic Syndrome Subjects
M Rezaei, A Palizban, S Zamani-doabi, M Shojaee
Journal of Biology and Today's World 2016
Rapid identification of familial hypercholesterolemia from electronic health records: The SEARCH study.
Safarova MS, Liu H, Kullo IJ
Journal of Clinical Lipidology 2016
Familial Hypercholesterolemia—Epidemiology, Diagnosis, and Screening
S Singh, V Bittner
Current Atherosclerosis Reports 2015
Cholesterol-lowering effects and potential mechanisms of different polar extracts from Cyclocarya paliurus leave in hyperlipidemic mice
C Jiang, Q Wang, YJ Wei, N Yao, Z Wu, Y Ma, Z Lin, M Zhao, C Che, X Yao, J Zhang, Z Yin
Journal of Ethnopharmacology 2015
Hypertriglyceridemia in the Genomic Era: A New Paradigm
GF Lewis, C Xiao, RA Hegele
Endocrine reviews 2015
Genetics of Familial Hypercholesterolemia
A Brautbar, E Leary, K Rasmussen, DP Wilson, RD Steiner, S Virani
Current Atherosclerosis Reports 2015
New Approaches in Detection and Treatment of Familial Hypercholesterolemia
ML Hartgers, KK Ray, GK Hovingh
Current Cardiology Reports 2015
Next-generation gene discovery for variants of large impact on lipid traits:
E Rosenthal, E Blue, GP Jarvik
Current Opinion in Lipidology 2015
Treatment of primary hypertriglyceridemia states – General approach and the role of extracorporeal methods
C Stefanutti, U Julius
Atherosclerosis Supplements 2015
Systematic analysis of variants related to familial hypercholesterolemia in families with premature myocardial infarction
I Brænne, M Kleinecke, B Reiz, E Graf, T Strom, T Wieland, M Fischer, T Kessler, C Hengstenberg, T Meitinger, J Erdmann, H Schunkert
European Journal of Human Genetics 2015
The effect of an Apolipoprotein A-I- containing HDL-mimetic Particle (CER-001) on carotid artery wall thickness in Patients with Homozygous Familial Hypercholesterolemia
GK Hovingh, LP Smits, C Stefanutti, H Soran, S Kwok, J Graaf, D Gaudet, CH Keyserling, H Klepp, J Frick, JF Paolini, JL Dasseux, JJ Kastelein, ES Stroes
American Heart Journal 2015
Statins decrease the risk of stroke in individuals with heterozygous familial hypercholesterolemia: A systematic review and meta-analysis
F Barkas, M Elisaf, H Milionis
Atherosclerosis 2015
Challenges in the Diagnosis and Treatment of Homozygous Familial Hypercholesterolemia
MK Ito, GF Watts
Drugs 2015
Prevalence and management of familial hypercholesterolaemia in coronary patients: An analysis of EUROASPIRE IV
GD Backer, J Besseling, J Chapman, GK Hovingh, JJ Kastelein, K Kotseva, K Ray, Ž Reiner, D Wood, DD Bacquer
Atherosclerosis 2015
Familial Hypercholesterolemia and the 2013 American College of Cardiology/American Heart Association Guidelines: Myths, Oversimplification and Misinterpretation versus Facts
JW Knowles, NJ Stone, CM Ballantyne
The American Journal of Cardiology 2015
Secondary hypertriglyceridemia in children and adolescents
PR Blackett, DP Wilson, C McNeal
Journal of Clinical Lipidology 2015
Primary hypertriglyceridemia in children and adolescents
AS Shah, DP Wilson
Journal of Clinical Lipidology 2015
Familial hypercholesterolemia in children and adolescents: A clinical perspective
SD de Ferranti
Journal of Clinical Lipidology 2015
Contribution of mutations in low density lipoprotein receptor (LDLR) and lipoprotein lipase (LPL) genes to familial combined hyperlipidemia (FCHL): A reappraisal by using a resequencing approach
I Minicocci, C Prisco, A Montali, AD Costanzo, F Ceci, G Pigna, M Arca
Atherosclerosis 2015
Frequency of familial hypercholesterolemia in patients with early-onset coronary artery disease admitted to a coronary care unit
J Pang, EB Poulter, DA Bell, TR Bates, VL Jefferson, GS Hillis, CJ Schultz, GF Watts
Journal of Clinical Lipidology 2015
Combined dyslipidemia in childhood
RE Kavey
Journal of Clinical Lipidology 2015
Universal Screening for Familial Hypercholesterolemia in Children
G Klančar, U Grošelj, J Kovač, N Bratanič, N Bratina, KT Podkrajšek, T Battelino
Journal of the American College of Cardiology 2015
Nutritional Intervention in Metabolic Syndrome
H Takahashi, L Roma, M Silva
Nutritional Intervention in Metabolic Syndrome 2015
Dyslipidemias: Pathophysiology, Evaluation and Management
A Garg
2015
Searching for missing heritability: Designing rare variant association studies
O Zuk, SF Schaffner, K Samocha, R Do, E Hechter, S Kathiresan, MJ Daly, BM Neale, SR Sunyaev, ES Lander
Proceedings of the National Academy of Sciences 2014
Management of Hypercholesterolemia in Children
MJ Braamskamp, BA Hutten, A Wiegman, JJ Kastelein
Pediatric Drugs 2014
Bile acid synthesis precursors in familial combined hyperlipidemia: The oxysterols 24S-hydroxycholesterol and 27-hydroxycholesterol
L Baila-Rueda, R Mateo-Gallego, E Jarauta, I Castro-Orós, AM Bea, A Cenarro, F Civeira
Biochemical and Biophysical Research Communications 2014
Familial combined hyperlipidemia: from molecular insights to tailored therapy
MM van Greevenbroek, AF Stalenhoef, J Graaf, MC Brouwers
Current Opinion in Lipidology 2014
Homozygous autosomal dominant hypercholesterolaemia in the Netherlands: prevalence, genotype-phenotype relationship, and clinical outcome
B Sjouke, DM Kusters, I Kindt, J Besseling, JC Defesche, EJ Sijbrands, JE van Lennep, AF Stalenhoef, A Wiegman, J Graaf, SW Fouchier, JJ Kastelein, GK Hovingh
European Heart Journal 2014
Antihyperlipidemic Therapies Targeting PCSK9:
M Weinreich, WH Frishman
Cardiology in Review 2014
The Severe Hypercholesterolemia Phenotype
AD Sniderman, S Tsimikas, S Fazio
Journal of the American College of Cardiology 2014
Antihyperglycemic and antihyperlipidemic effects of the methanol extracts of Cleome ramosissima Parl., Barleria bispinosa (Forssk.) Vahl. and Tribulus macropterus Boiss
SM Ezzat, E Abdel-Sattar, FM Harraz, SA Ghareib
Bulletin of Faculty of Pharmacy Cairo University 2014
Targeted genetic testing for familial hypercholesterolaemia using next generation sequencing: a population-based study
PJ Norsworthy, J Vandrovcova, ER Thomas, A Campbell, SM Kerr, J Biggs, L Game, AK Soutar, BH Smith, AF Dominiczak, DJ Porteous, AD Morris, G Scotland, TJ Aitman
BMC Medical Genetics 2014
A Review on the Traditional Chinese Medicinal Herbs and Formulae with Hypolipidemic Effect
TT Sham, CO Chan, YH Wang, JM Yang, DK Mok, SW Chan
BioMed Research International 2014
Pharmacologic Inhibition of Sphingomyelin Synthase (SMS) Activity Reduces Apolipoprotein-B Secretion from Hepatocytes and Attenuates Endotoxin-Mediated Macrophage Inflammation
B Lou, J Dong, Y Li, T Ding, T Bi, Y Li, X Deng, D Ye, XC Jiang, D Chakravortty
PloS one 2014
Whole-exome sequencing in an extended family with myocardial infarction unmasks familial hypercholesterolemia
I Brænne, B Reiz, A Medack, M Kleinecke, M Fischer, S Tuna, C Hengstenberg, P Deloukas, J Erdmann, H Schunkert
BMC Cardiovascular Disorders 2014
Exome sequencing identifies rare LDLR and APOA5 alleles conferring risk for myocardial infarction
R Do, NO Stitziel, HH Won, AB Jørgensen, S Duga, PA Merlini, A Kiezun, M Farrall, A Goel, O Zuk, I Guella, R Asselta, LA Lange, GM Peloso, PL Auer, D Girelli, N Martinelli, DN Farlow, MA DePristo, R Roberts, AF Stewart, D Saleheen, J Danesh, SE Epstein, S Sivapalaratnam, GK Hovingh, JJ Kastelein, NJ Samani, H Schunkert, J Erdmann, SH Shah, WE Kraus, R Davies, M Nikpay, CT Johansen, J Wang, RA Hegele, E Hechter, W Marz, ME Kleber, J Huang, AD Johnson, M Li, GL Burke, M Gross, Y Liu, TL Assimes, G Heiss, EM Lange, AR Folsom, HA Taylor, O Olivieri, A Hamsten, R Clarke, DF Reilly, W Yin, MA Rivas, P Donnelly, JE Rossouw, BM Psaty, DM Herrington, JG Wilson, SS Rich, MJ Bamshad, RP Tracy, LA Cupples, DJ Rader, MP Reilly, JA Spertus, S Cresci, J Hartiala, WH Tang, SL Hazen, H Allayee, AP Reiner, CS Carlson, C Kooperberg, RD Jackson, E Boerwinkle, ES Lander, SM Schwartz, DS Siscovick, R McPherson, A Tybjaerg-Hansen, GR Abecasis, H Watkins, DA Nickerson, D Ardissino, SR Sunyaev, CJ O'Donnell, D Altshuler, S Gabriel, S Kathiresan
Nature 2014
Recommendations for the Management of Patients with Familial Hypercholesterolemia
DI Feldman, MJ Blaha, RD Santos, SR Jones, RS Blumenthal, PP Toth, LS Sperling, SS Martin
Current Atherosclerosis Reports 2014
Inducing pluripotency for disease modeling, drug development and craniofacial applications
V Rosa, WS Toh, T Cao, W Shim
Expert Opinion on Biological Therapy 2014
Control del colesterol-LDL en pacientes con dislipidemias genéticas seguidos en unidades de lípidos y riesgo vascular de la Sociedad Española de Arteriosclerosis
C Lahoz, JM Mostaza, X Pintó, JJ de la Cruz, JR Banegas, J Pedro-Botet
Clínica e Investigación en Arteriosclerosis 2014
Small dense LDL cholesterol measured by homogeneous assay in Japanese healthy controls, metabolic syndrome and diabetes patients with or without a fatty liver
K Kikkawa, K Nakajima, Y Shimomura, Y Tokita, T Machida, H Sumino, M Murakami
Clinica Chimica Acta 2014
The genetic architecture of the familial hyperlipidaemia syndromes: rare mutations and common variants in multiple genes
PJ Talmud, M Futema, SE Humphries
Current Opinion in Lipidology 2014
Hiperlipidemia familiar combinada: documento de consenso
P Mata, R Alonso, A Ruíz-Garcia, JL Díaz-Díaz, N González, T Gijón-Conde, C Martínez-Faedo, I Morón, E Arranz, R Aguado, R Argueso, LP de Isla
Atención Primaria 2014
Determinants of VLDL composition and apo B-containing particles in familial combined hyperlipidemia
I Cruz-Bautista, R Mehta, J Cabiedes, C García-Ulloa, LE Guillen-Pineda, P Almeda-Valdés, D Cuevas-Ramos, CA Aguilar-Salinas
Clinica Chimica Acta 2014
Significant gaps in awareness of familial hypercholesterolemia among physicians in selected Asia-Pacific countries: A pilot study
J Pang, DR Sullivan, M Harada-Shiba, PY Ding, S Selvey, S Ali, GF Watts
Journal of Clinical Lipidology 2014
Update on Screening, Etiology, and Treatment of Dyslipidemia in Children
V Bamba
The Journal of clinical endocrinology and metabolism 2014
Tumor necrosis factor beta NcoI polymorphism (rs909253) is associated with inflammatory and metabolic markers in acute ischemic stroke
J de Sousa Parreira, AP Kallaur, MF Lehmann, SR Oliveira, DA Frizon, F Delongui, MC de Araújo, C Rossato, JT de Almeida, LM Pelegrino, EF Bragato, HK Morimoto, AN Simão, DR Kaimen-Maciel, EM Reiche
Metabolic Brain Disease 2014
Hiperlipidemia familiar combinada: documento de consenso
P Mata, R Alonso, A Ruíz-Garcia, JL Díaz-Díaz, N González, T Gijón-Conde, C Martínez-Faedo, I Morón, E Arranz, R Aguado, R Argueso, LP de Isla
Atención Primaria 2014
Plasma proprotein convertase subtilisin kexin type 9 levels are related to markers of cholesterol synthesis in familial combined hyperlipidemia
MC Brouwers, RJ Konrad, TM Himbergen, A Isaacs, S Otokozawa, JS Troutt, EJ Schaefer, MM Greevenbroek, AF Stalenhoef, J Graaf
Nutrition, Metabolism and Cardiovascular Diseases 2013
Emery and Rimoin's Principles and Practice of Medical Genetics
DC Wallace, MT Lott, V Procaccio
Emery and Rimoin's Principles and Practice of Medical Genetics 2013
Obesity, adiposity, and dyslipidemia: A consensus statement from the National Lipid Association
HE Bays, PP Toth, PM Kris-Etherton, N Abate, LJ Aronne, WV Brown, JM Gonzalez-Campoy, SR Jones, R Kumar, RL Forge, VT Samuel
Journal of Clinical Lipidology 2013
New Therapies Targeting apoB Metabolism for High-Risk Patients with Inherited Dyslipidaemias: What Can the Clinician Expect?
A Sahebkar, GF Watts
Cardiovascular Drugs and Therapy 2013
Two novel mutations in apolipoprotein C3 underlie atheroprotective lipid profiles in families: Two novel mutations in apolipoprotein C3
AE Bochem, JC Capelleveen, GM Dallinga-Thie, AW Schimmel, MM Motazacker, I Tietjen, RR Singaraja, MR Hayden, JJ Kastelein, ES Stroes, GK Hovingh
Clinical Genetics 2013
Pediatric lipid screening
CJ McNeal, L Underland, DP Wilson, PR Blackett
Clinical Lipidology 2013
Joint Linkage and Association Analysis with Exome Sequence Data Implicates SLC25A40 in Hypertriglyceridemia
EA Rosenthal, J Ranchalis, DR Crosslin, A Burt, JD Brunzell, AG Motulsky, DA Nickerson, EM Wijsman, GP Jarvik
The American Journal of Human Genetics 2013
Antidiabetic and antihyperlipidemic activity of Piper longum root aqueous extract in STZ induced diabetic rats
SA Nabi, RB Kasetti, S Sirasanagandla, TK Tilak, MV Kumar, CA Rao
BMC complementary and alternative medicine 2013
Association of RXR-Gamma Gene Variants with Familial Combined Hyperlipidemia: Genotype and Haplotype Analysis
F Sentinelli, I Minicocci, A Montali, L Nanni, S Romeo, M Incani, MG Cavallo, A Lenzi, M Arca, MG Baroni
Journal of Lipids 2013
Oral administration of alkaloid fraction from Ruta graveolens inhibits oxidative stress and inflammation in hypercholesterolemic rabbits
M Ratheesh, A Helen
Pharmaceutical Biology 2013
Pathologie
M Stolte, J Rüschoff, G Klöppel
Der Pathologe 2013
Haemostatic and inflammatory alterations in familial hypercholesterolaemia, and the impact of angiotensin II infusion
M Ekholm, T Kahan, G Jörneskog, J Brinck, NH Wallén
Journal of Renin-Angiotensin-Aldosterone System 2013
Liver phospholipid transfer protein (PLTP) expression with a PLTP-null background promotes very low-density lipoprotein production in mice
A Yazdanyar, XC Jiang
Hepatology 2012
The genetics of familial combined hyperlipidaemia.
Brouwers MC, van Greevenbroek MM, Stehouwer CD, de Graaf J, Stalenhoef AF
Nature reviews. Endocrinology 2012
Veratric acid ameliorates hyperlipidemia and oxidative stress in Wistar rats fed an atherogenic diet
B Raja, M Saravanakumar, G Sathya
Molecular and Cellular Biochemistry 2012
Antidiabetic, antihyperlipidemic and antioxidant activities of methanolic extract of Amaranthus viridis Linn in alloxan induced diabetic rats
BS Kumar, K Lakshman, KN Jayaveea, DS Shekar, S Khan, BS Thippeswamy, VP Veerapur
Experimental and Toxicologic Pathology 2012
Methods in Enzymology
JD Stone, AS Chervin, DH Aggen, DM Kranz
Protein Engineering for Therapeutics Part B 2012
The genetics of familial combined hyperlipidaemia
MC Brouwers, MM van Greevenbroek, CD Stehouwer, J Graaf, AF Stalenhoef
Nature Reviews Endocrinology 2012
Gout
E Krishnan
Gout &amp Other Crystal Arthropathies 2012
Drug Therapy of Hypercholesterolaemia in Children and Adolescents :
MJ Braamskamp, FA Wijburg, A Wiegman
Drugs 2012
A Model of Care for Familial Hypercholesterolaemia: Key Role for Clinical Biochemistry
GF Watts, DR Sullivan, FM van Bockxmeer, N Poplawski, I Hamilton-Craig, PM Clifton, RC O'Brien, PM George, JR Burnett
The Clinical Biochemist Reviews 2012
Apolipoprotein E gene mutations in subjects with mixed hyperlipidemia and a clinical diagnosis of familial combined hyperlipidemia
M Solanas-Barca, I Castro-Orós, R Mateo-Gallego, M Cofán, N Plana, J Puzo, E Burillo, P Martín-Fuentes, E Ros, L Masana, M Pocoví, F Civeira, A Cenarro
Atherosclerosis 2012
Hiperlipidemias primarias
SV Martín, SG Pastor, ML Triguero, AH Mijares
Medicine - Programa de Formación Médica Continuada Acreditado 2012
Tietz Textbook of Clinical Chemistry and Molecular Diagnostics
EJ Lamb, CP Price
Tietz Textbook of Clinical Chemistry and Molecular Diagnostics 2012
Proanthocyanidin Oligomers Isolated from Salacia reticulata leaves potently Inhibit Pancreatic Lipase Activity
K Koga, M Hisamura, T Kanetaka, K Yoshino, Y Matsuo, T Tanaka
Journal of Food Science 2012
Founder mutations in Tunisia: implications for diagnosis in North Africa and Middle East
L Romdhane, R Kefi, H Azaiez, NB Halim, K Dellagi, S Abdelhak
Orphanet Journal of Rare Diseases 2012
The impact of phospholipid transfer protein (PLTP) on lipoprotein metabolism
XC Jiang, W Jin, MM Hussain
Nutrition & Metabolism 2012
Up-Regulation of the Complement System in Subcutaneous Adipocytes from Nonobese, Hypertriglyceridemic Subjects Is Associated with Adipocyte Insulin Resistance
MM van Greevenbroek, S Ghosh, CJ van der Kallen, MC Brouwers, CG Schalkwijk, CD Stehouwer
The Journal of clinical endocrinology and metabolism 2012
Drug Therapy of Hypercholesterolaemia in Children and Adolescents:
MJ Braamskamp, FA Wijburg, A Wiegman
Drugs 2012
Encyclopedia of Life Sciences
B Dahlbäck
Encyclopedia of Life Sciences 2011
Familial Hypercholesterolemias: Prevalence, genetics, diagnosis and screening recommendations from the National Lipid Association Expert Panel on Familial Hypercholesterolemia
PN Hopkins, PP Toth, CM Ballantyne, DJ Rader
Journal of Clinical Lipidology 2011
A classification of lipoprotein disorders: implications for clinical management
DR Sullivan, B Lewis
Clinical Lipidology 2011
A Novel Pathogenic Nonsense Triple-Nucleotide Mutation in the Low-Density Lipoprotein Receptor Gene and Its Clinical Correlation with Familial Hypercholesterolemia
M Ajmal, W Ahmed, N Akhtar, A Sadeque, A Khalid, SH Ali, N Ahmed, M Azam, R Qamar
Genetic Testing and Molecular Biomarkers 2011
Genetics and molecular biology
J Pétremand, C Widmann
Current Opinion in Lipidology 2011
Molecular genetic epidemiology of homozygous familial hypercholesterolemia in the Hokuriku district of Japan
H Mabuchi, A Nohara, T Noguchi, J Kobayashi, M Kawashiri, H Tada, C Nakanishi, M Mori, M Yamagishi, A Inazu, J Koizumi
Atherosclerosis 2011
Arterial endothelial function and wall thickness in familial hypercholesterolemia and familial combined hyperlipidemia and the effect of statins. A systematic review and meta-analysis
C Masoura, C Pitsavos, K Aznaouridis, I Skoumas, C Vlachopoulos, C Stefanadis
Atherosclerosis 2011
Future issues, public policy, and public awareness of Familial Hypercholesterolemias: Recommendations from the National Lipid Association Expert Panel on Familial Hypercholesterolemia
AC Goldberg, JG Robinson, WC Cromwell, JL Ross, PE Ziajka
Journal of Clinical Lipidology 2011
Estudio genético de la implicación del gen USF1 en el desarrollo del síndrome metabólico
M Strunk, EJ Simón, AM Sanz, JP Foncillas, FC Murillo, ÁL García-Otín
Clínica e Investigación en Arteriosclerosis 2011
Plasma proprotein convertase subtilisin kexin type 9 is a heritable trait of familial combined hyperlipidaemia
MC Brouwers, MM van Greevenbroek, JS Troutt, A Bonner Freeman, A Lu, NC Schaper, RJ Konrad, CD Stehouwer
Clinical Science 2011
Relationship between type 2 diabetes mellitus and a novel polymorphism C698T in C5L2 in the Chinese Han population
YY Zheng, X Xie, YT Ma, YN Yang, ZY Fu, XM Li, X Ma, BD Chen, F Liu
Endocrine 2011
Annual Reports in Medicinal Chemistry
JJ Liu, TW Lee
Annual Reports in Medicinal Chemistry Volume 46 2011
Serum triglycerides and risk of cardiovascular disease
AC Boullart, J Graaf, AF Stalenhoef
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids 2011
Management of Type IIb Dyslipidemia
H Arai, S Ishibashi, H Bujo, T Hayashi, S Yokoyama, S Oikawa, J Kobayashi, K Shirai, T Ota, S Yamashita, T Gotoda, M Harada-Shiba, H Sone, M Eto, H Suzuki, N Yamada
Journal of Atherosclerosis and Thrombosis 2011
Williams Textbook of Endocrinology
DW Cooke, SA Divall, S Radovick
Williams Textbook of Endocrinology 2011
Preventive Cardiology: Companion to Braunwald's Heart Disease
PN Hopkins
Preventive Cardiology: Companion to Braunwald's Heart Disease 2011
Genome-Wide Linkage Scan of a Pedigree with Familial Hypercholesterolemia Suggests Susceptibility Loci on Chromosomes 3q25-26 and 21q22
X Wang, X Li, YB Zhang, F Zhang, L Sun, J Lin, DM Wang, LY Wang, R Krahe
PloS one 2011
Triglyceride-rich lipoproteins and high-density lipoprotein cholesterol in patients at high risk of cardiovascular disease: evidence and guidance for management.
Chapman MJ, Ginsberg HN, Amarenco P, Andreotti F, Borén J, Catapano AL, Descamps OS, Fisher E, Kovanen PT, Kuivenhoven JA, Lesnik P, Masana L, Nordestgaard BG, Ray KK, Reiner Z, Taskinen MR, Tokgözoglu L, Tybjærg-Hansen A, Watts GF
European Heart Journal 2011
R353Q polymorphism in the factor VII gene and cardiovascular risk in Heterozygous Familial Hypercholesterolemia: a case-control study.
Criado-García J, Fuentes F, Cruz-Teno C, García-Rios A, Jiménez-Morales A, Delgado-Lista J, Mata P, Alonso R, López-Miranda J, Pérez-Jiménez F
Lipids in Health and Disease 2011
Encouraging appropriate treatment for familial hypercholesterolemia
PN Hopkins
Clinical Lipidology 2010
Linkage and association analyses identify a candidate region for apoB level on chromosome 4q32.3 in FCHL families
EM Wijsman, JH Rothstein, RP Igo, JD Brunzell, AG Motulsky, GP Jarvik
Human Genetics 2010
Genetic variants in adipose triglyceride lipase influence lipid levels in familial combined hyperlipidemia
L Nanni, F Quagliarini, F Megiorni, A Montali, I Minicocci, F Campagna, A Pizzuti, M Arca
Atherosclerosis 2010
Carotid distension and distensibility impairment in individuals affected by familial combined hyperlipidemia
T Montalcini, G Gorgone, C Gazzaruso, A Pujia
Atherosclerosis 2010
Carotid atherosclerosis and lipoprotein particle subclasses in familial hypercholesterolaemia and familial combined hyperlipidaemia
E Jarauta, R Mateo-Gallego, R Gilabert, N Plana, M Junyent, E Groot, A Cenarro, L Masana, E Ros, F Civeira
Nutrition, Metabolism and Cardiovascular Diseases 2010
Adiponectin in Members of Families With Familial Combined Hyperlipidemia
D Karásek, H Vaverková, M Halenka, D Jackuliaková, Z Fryšák, DN Ing
The Endocrinologist 2010
Assessment of liver stiffness in subjects affected by familial combined hyperlipidaemia with hepatic steatosis
S Riggio, F Mamone, G Mandraffino, S Maimone, A Alibrandi, L Manti, C Saitta, PF Tripodi, MA Sardo, G Squadrito, A Saitta
European Journal of Clinical Investigation 2010
Novel drugs in familial combined hyperlipidemia: lessons from type 2 diabetes mellitus
MC Brouwers, J Graaf, MM van Greevenbroek, N Schaper, CD Stehouwer, AF Stalenhoef
Current Opinion in Lipidology 2010
A case report of a diabetic woman with very low HDL cholesterol
L Chaychi, WB Kinlaw, BF Asztalos, EJ Schaefer
Journal of Clinical Lipidology 2010
Postprandial metabolic heterogeneity in men with primary dyslipidaemia
AN Pavlidis, GD Kolovou, KK Anagnostopoulou, PC Petrou, DV Cokkinos
Archives of Medical Science : AMS 2010
Medicina Personalizada Posgenómica. Conceptos Prácticos Para Clínicos
GS Sales, JS Tobella
Medicina Personalizada Posgenómica. Conceptos Prácticos Para Clínicos 2010
Hypertriglyceridaemia: Aetiology, Complications and Management
DJ Blom
Journal of Endocrinology, Metabolism and Diabetes of South Africa 2010
Application and validation of a diagnostic algorithm for the atherogenic apoB dyslipoproteinemias: ApoB dyslipoproteinemias in a Dutch population-based study
S Holewijn, AD Sniderman, M den Heijer, DW Swinkels, AF Stalenhoef, J de Graaf
European Journal of Clinical Investigation 2010
Familial Combined Hyperlipidemia Is Associated With Alterations in the Cholesterol Synthesis Pathway
TM van Himbergen, S Otokozawa, NR Matthan, EJ Schaefer, A Buchsbaum, M Ai, LJ van Tits, J de Graaf, AF Stalenhoef
Arteriosclerosis, thrombosis, and vascular biology 2010
Atlas of Atherosclerosis and Metabolic Syndrome
SM Grundy
2010
High Density Lipoproteins, Dyslipidemia, and Coronary Heart Disease
EJ Schaefer
2010
Family Coronary Heart Disease: A Call to Action: Family coronary heart disease
HR Superko, R Roberts, B Garrett, L Pendyala, S King
Clinical Cardiology 2010
Molecular spectrum of autosomal dominant hypercholesterolemia in France.
Marduel M, Carrié A, Sassolas A, Devillers M, Carreau V, Di Filippo M, Erlich D, Abifadel M, Marques-Pinheiro A, Munnich A, Junien C, Boileau C, Varret M, Rabès JP
Human Mutation 2010
Pulmonary surfactant: an immunological perspective
ZC Chroneos, Z Sever-Chroneos, VL Shepherd
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2009
A Systems Genetics Approach Implicates USF1, FADS3, and Other Causal Candidate Genes for Familial Combined Hyperlipidemia
CL Plaisier, S Horvath, A Huertas-Vazquez, I Cruz-Bautista, MF Herrera, T Tusie-Luna, C Aguilar-Salinas, P Pajukanta, JD Storey
PLoS genetics 2009
Triglycerides and cardiovascular risk
KE Harchaoui, ME Visser, JJ Kastelein, ES Stroes, GM Dallinga-Thie
Current cardiology reviews 2009
The SLIM Study: Slo-Niacin(R) and Atorvastatin Treatment of Lipoproteins and Inflammatory Markers in Combined Hyperlipidemia
RH Knopp, BM Retzlaff, B Fish, A Dowdy, B Twaddell, T Nguyen, P Paramsothy
Journal of Clinical Lipidology 2009
Upstream transcription factor 1 influences plasma lipid and metabolic traits in mice
S Wu, R Mar-Heyming, EZ Dugum, NA Kolaitis, H Qi, P Pajukanta, LW Castellani, AJ Lusis, TA Drake
Human Molecular Genetics 2009
A nonsynonymous SNP within PCDH15 is associated with lipid traits in familial combined hyperlipidemia
A Huertas-Vazquez, CL Plaisier, R Geng, BE Haas, J Lee, MM Greevenbroek, C der Kallen, TW de Bruin, MR Taskinen, KN Alagramam, P Pajukanta
Human Genetics 2009
OSBPL10, a novel candidate gene for high triglyceride trait in dyslipidemic Finnish subjects, regulates cellular lipid metabolism
J Perttilä, K Merikanto, J Naukkarinen, I Surakka, NW Martin, K Tanhuanpää, V Grimard, MR Taskinen, C Thiele, V Salomaa, A Jula, M Perola, I Virtanen, L Peltonen, VM Olkkonen
Journal of Molecular Medicine 2009
Small and dense LDL in familial combined hyperlipidemia and N291S polymorphism of the lipoprotein lipase gene
A López-Ruiz, MM Jarabo, ML Martínez-Triguero, M Morales-Suárez-Varela, E Solá, C Bañuls, M Casado, A Hernández-Mijares
Lipids in Health and Disease 2009
Combined hyperlipidemia in relation to race/ethnicity, obesity, and insulin resistance in the Multi-Ethnic Study of Atherosclerosis
P Paramsothy, R Knopp, AG Bertoni, MY Tsai, T Rue, SR Heckbert
Metabolism: clinical and experimental 2009
ApoB versus non-HDL-C: What to do when they disagree
A Sniderman, K Williams, C Cobbaert
Current Atherosclerosis Reports 2009
Angiotensin II infusion in man is proinflammatory but has no short-term effects on thrombin generation in vivo
M Ekholm, T Kahan, G Jörneskog, A Bröijersen, NH Wallén
Thrombosis Research 2009
Cardiovascular complications in familial combined hyperlipidemia: beyond the atherogenic dyslipidemia
MC Brouwers, CD Stehouwer
Clinical Lipidology 2009
Small dense LDL-cholesterol determined by a simple precipitation assay for screening familial combined hyperlipidemia
T Hirano, K Nohtomi, Y Sato, K Kamata, Y Ito
Atherosclerosis 2009
Familial-combined hyperlipidaemia in very young myocardial infarction survivors (<=40 years of age)
F Wiesbauer, H Blessberger, D Azar, G Goliasch, O Wagner, L Gerhold, K Huber, K Widhalm, F Abdolvahab, G Sodeck, G Maurer, M Schillinger
European Heart Journal 2009
Fenofibrate ameliorates diabetic and dyslipidemic profiles in KKAy mice partly via down-regulation of 11β-HSD1, PEPCK and DGAT2
RA Srivastava
European Journal of Pharmacology 2009
Increased arterial stiffness in familial combined hyperlipidemia
MC Brouwers, KD Reesink, MM van Greevenbroek, JM Meinders, CJ van der Kallen, N Schaper, AP Hoeks, CD Stehouwer
Journal of Hypertension 2009
Mutations and polymorphisms in the proprotein convertase subtilisin kexin 9 (PCSK9) gene in cholesterol metabolism and disease
M Abifadel, JP Rab��s, M Devillers, A Munnich, D Erlich, C Junien, M Varret, C Boileau
Human Mutation 2009
Endothelial haemostatic markers in members of families with familial combined hyperlipidemia
D Karásek, H Vaverková, M Halenka, L Slavík, D Novotný
Thrombosis Research 2009
Antihyperlipidemic effect of the methanolic extract from Lagenaria siceraria Stand. fruit in hyperlipidemic rats
BV Ghule, MH Ghante, AN Saoji, PG Yeole
Journal of Ethnopharmacology 2009
Anti-atherogenic effects of centipede acidic protein in rats fed an atherogenic diet
Y Wu, J Li, J Wang, Q Si, J Zhang, Y Jiang, L Chu
Journal of Ethnopharmacology 2009
Aortic calcifications in familial hypercholesterolemia: Potential role of the low-density lipoprotein receptor gene
K Alrasadi, K Alwaili, Z Awan, D Valenti, P Couture, J Genest
American Heart Journal 2009
Effect of Combination Nicotinic Acid and Gemfibrozil Treatment on Intermediate Density Lipoprotein, and Subclasses of Low Density Lipoprotein and High Density Lipoprotein in Patients With Combined Hyperlipidemia
HR Superko, BC Garrett, SB King, KM Momary, NA Chronos, PD Wood
The American Journal of Cardiology 2009
Efficacy of Different Fractions of Anethum graveolens Leaves on Serum Lipoproteins and Serum and Liver Oxidative Status in Experimentally Induced Hypercholesterolaemic Rat Models
S Bahramikia, R Yazdanparast
The American journal of Chinese medicine 2009
Pharmacology and Therapeutics
BL Clarke, S Khosla
Pharmacology & Therapeutics 2009
Galanin Preproprotein Is Associated With Elevated Plasma Triglycerides
CL Plaisier, M Kyttälä, D Weissglas-Volkov, JS Sinsheimer, A Huertas-Vazquez, L Riba, S Ramírez-Jiménez, TW de Bruin, T Tusié-Luna, BE Aouizerat, CR Pullinger, MJ Malloy, JP Kane, I Cruz-Bautista, MF Herrera, C Aguilar-Salinas, J Kuusisto, M Laakso, MR Taskinen, CJ van der Kallen, P Pajukanta
Arteriosclerosis, thrombosis, and vascular biology 2009
Molecular Diagnostics: Promises and Possibilities
M Debnath, GB Prasad, PS Bisen
2009
Genetics of premature myocardial infarction
R Roberts
Current Atherosclerosis Reports 2008
Investigation and management of hypertriglyceridaemia
G Ferns, V Keti, B Griffin
Journal of clinical pathology 2008
Novartis Foundation Symposia
EJ Campbell
Ciba Foundation Symposium 44 - Research and Medical Practice: Their Interaction 2008
Fundamental and Clinical Cardiology Series
PD Stein
Cardiovascular Disease in the Elderly 2008
Insulin resistance and oxidative stress in familial combined hyperlipidemia
S Martinez-Hervas, M Fandos, JT Real, O Espinosa, FJ Chaves, GT Saez, A Salvador, C Cerdá, R Carmena, JF Ascaso
Atherosclerosis 2008
Frequency of Low-Density Lipoprotein Receptor Gene Mutations in Patients With a Clinical Diagnosis of Familial Combined Hyperlipidemia in a Clinical Setting
F Civeira, E Jarauta, A Cenarro, AL García-Otín, D Tejedor, D Zambón, M Mallen, E Ros, M Pocoví
Journal of the American College of Cardiology 2008
Advances in the management of hyperlipidemia-induced atherosclerosis
LR Tannock
Expert Review of Cardiovascular Therapy 2008
Tocotrienols
C Elson, H Mo
Tocotrienols 2008
A Null Mutation in Human APOC3 Confers a Favorable Plasma Lipid Profile and Apparent Cardioprotection
TI Pollin, CM Damcott, H Shen, SH Ott, J Shelton, RB Horenstein, W Post, JC McLenithan, LF Bielak, PA Peyser, BD Mitchell, M Miller, JR O'Connell, AR Shuldiner
Science 2008
Hypolipidemic activity ofAnethum graveolens in rats
V Hajhashemi, N Abbasi
Phytotherapy Research 2008
Paraoxonase (PON1) is associated with familial combined hyperlipidemia
TM van Himbergen, LJ van Tits, E Avest, M Roest, HA Voorbij, J Graaf, AF Stalenhoef
Atherosclerosis 2008
Allelic Variants of Upstream Transcription Factor 1 Associate With Carotid Artery Intima-Media Thickness
A Collings, S Höyssä, M Fan, M Kähönen, N Hutri-Kähönen, J Marniemi, M Juonala, JS Viikari, OT Raitakari, TJ Lehtimäki
Circulation Journal 2008
A diagnostic algorithm for the atherogenic apolipoprotein B dyslipoproteinemias
J Graaf, P Couture, A Sniderman
Nature Clinical Practice Endocrinology & Metabolism 2008
APOA5 genetic variants are markers for classic hyperlipoproteinemia phenotypes and hypertriglyceridemia
J Wang, MR Ban, BA Kennedy, S Anand, S Yusuf, MW Huff, RL Pollex, RA Hegele
Nature Clinical Practice Cardiovascular Medicine 2008
Spousal Concordance for Major Coronary Risk Factors: A Systematic Review and Meta-Analysis
AD Castelnuovo, G Quacquaruccio, MB Donati, G Gaetano, L Iacoviello
American Journal of Epidemiology 2008
Primary Hyperlipidemia
T Teramoto, J Sasaki, H Ueshima, G Egusa, M Kinoshita, K Shimamoto, H Daida, S Biro, K Hirobe, T Funahashi, K Yokote, M Yokode
Journal of Atherosclerosis and Thrombosis 2008
Proposed Guidelines for Hypertriglyceridemia in Japan with Non-HDL Cholesterol as the Second Target
H Shimano, H Arai, M Harada-Shiba, H Ueshima, T Ohta, S Yamashita, T Gotoda, Y Kiyohara, T Hayashi, J Kobayashi, K Shimamoto, H Bujo, S Ishibashi, K Shirai, S Oikawa, Y Saito, N Yamada
Journal of Atherosclerosis and Thrombosis 2008
Carotid atherosclerosis in familial combined hyperlipidemia associated with the APOB/APOA-I ratio
M Junyent, D Zambón, R Gilabert, M Cofán, I Núñez, E Ros
Atherosclerosis 2008
Hepatoprotective effects of Solanum nigrum Linn extract against CCl4-iduced oxidative damage in rats
HM Lin, HC Tseng, CJ Wang, JJ Lin, CW Lo, FP Chou
Chemico-Biological Interactions 2008
Clinical and laboratory assessment of cardiovascular risk in children: Guidelines for screening, evaluation, and treatment
PO Kwiterovich
Journal of Clinical Lipidology 2008
Plasma PAI-1 levels are independently related to fatty liver and hypertriglyceridemia in familial combined hyperlipidemia, involvement of apolipoprotein E
MC Brouwers, J Govers-Riemslag, CG Schalkwijk, MM van Greevenbroek, CJ van der Kallen, O Bekers, MP van Dieijen-Visser, J Oever, MA Bilderbeek-Beckers, TW de Bruin, H Cate, CD Stehouwer
Thrombosis Research 2008
Oxidación del ADN como potencial factor de riesgo cardiovascular en la hiperlipemia familiar combinada
F Civeira, A Cenarro
Medicina Clínica 2008
Editorial comment: Frequent detection of familial hypercholesterolemia mutations in familial combined hyperlipidemia
GP Jarvik, JD Brunzell, AG Motulsky
Journal of the American College of Cardiology 2008
Comprehensive Lipid Management Versus Aggressive Low-Density Lipoprotein Lowering to Reduce Cardiovascular Risk
RH Knopp, P Paramsothy, B Atkinson, A Dowdy
The American Journal of Cardiology 2008
Association of Stearoyl-CoA Desaturase 1 Activity With Familial Combined Hyperlipidemia
R Mar-Heyming, M Miyazaki, D Weissglas-Volkov, NA Kolaitis, N Sadaat, C Plaisier, P Pajukanta, R M., TW de Bruin, JM Ntambi, AJ Lusis
Arteriosclerosis, thrombosis, and vascular biology 2008
Therapeutic Lipidology
MH Davidson, PP Toth, KC Maki, AM Gotto
2008
Optimal medical therapy with or without percutaneous coronary intervention for stable coronary disease: the COURAGE Study
John A Farmer
Current Atherosclerosis Reports 2008
Increased plasma levels of oxysterols, in vivo markers of oxidative stress, in patients with familial combined hyperlipidemia: Reduction during atorvastatin and fenofibrate therapy
M Arca, S Natoli, F Micheletta, S Riggi, ED Angelantonio, A Montali, TM Antonini, R Antonini, U Diczfalusy, L Iuliano
Free radical biology & medicine 2007
Effect of 3-month treatment of children and adolescents with familial and polygenic hypercholesterolaemia with a soya-substituted diet
D Weghuber, K Widhalm
British Journal of Nutrition 2007
Genetic heterogeneity of autosomal dominant hypercholesterolemia
M Varret, M Abifadel, JP Rabès, C Boileau
Clinical Genetics 2007
Hypertriglyceridemia: its etiology, effects and treatment
G Yuan, KZ Al-Shali, RA Hegele
CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 2007
TCF7L2 is associated with high serum triacylglycerol and differentially expressed in adipose tissue in families with familial combined hyperlipidaemia
A Huertas-Vazquez, C Plaisier, D Weissglas-Volkov, J Sinsheimer, S Canizales-Quinteros, I Cruz-Bautista, E Nikkola, M Herrera-Hernandez, A Davila-Cervantes, T Tusie-Luna, MR Taskinen, C Aguilar-Salinas, P Pajukanta
Diabetologia 2007
Effect of ScrF I polymorphism in the 2nd intron of the HMGCR gene on lipid-lowering response to simvastatin in Chinese diabetic patients
S Ying, YM Sun, XM Liu, CY An, YY Gao
Biochemical and Biophysical Research Communications 2007
Pioglitazone Improves Myocardial Blood Flow and Glucose Utilization in Nondiabetic Patients With Combined Hyperlipidemia
RP Naoumova, H Kindler, L Leccisotti, M Mongillo, MT Khan, C Neuwirth, M Seed, P Holvoet, J Betteridge, PG Camici
Journal of the American College of Cardiology 2007
Comparison of atorvastatin versus fenofibrate in reaching lipid targets and influencing biomarkers of endothelial damage in patients with familial combined hyperlipidemia
M Arca, A Montali, G Pigna, R Antonini, TM Antonini, P Luigi, A Fraioli, M Mastrantoni, M Maddaloni, C Letizia
Metabolism 2007
Kakkalide and Irisolidone: HMG-CoA Reductase Inhibitors Isolated from the Flower of Pueraria thunbergiana
SW Min, DH Kim
Biological & Pharmaceutical Bulletin 2007
High prevalence of major cardiovascular risk factors in first-degree relatives of individuals with familial premature coronary artery disease—The GENECARD project
C Hurrell, V Wietlisbach, V Jotterand, M Volet, V Lenain, P Nicod, R Darioli, F Paccaud, G Waeber, V Mooser
Atherosclerosis 2007
Fatty liver–based identification of two distinct hypertriglyceridemic subgroups in familial combined hyperlipidemia
MC Brouwers, MM van Greevenbroek, MA Bilderbeek-Beckers, MG Robertus-Teunissen, CJ van der Kallen, CD Stehouwer, TW de Bruin
Metabolism 2007
Pioglitazone added to conventional lipid-lowering treatment in familial combined hyperlipidaemia improves parameters of metabolic control: Relation to liver, muscle and regional body fat content
EL Thomas, E Potter, I Tosi, J Fitzpatrick, G Hamilton, V Amber, R Hughes, C North, P Holvoet, M Seed, DJ Betteridge, JD Bell, RP Naoumova
Atherosclerosis 2007
Do we need a statin-nicotinic acid-aspirin mini-polypill to treat combined hyperlipidaemia?
VG Athyros, K Tziomalos, DP Mikhailidis, ED Pagourelias, AI Kakafika, A Skaperdas, A Hatzitolios, A Karagiannis
Expert Opinion on Pharmacotherapy 2007
Hypertriglyceridemia
JD Brunzell
New England Journal of Medicine 2007
Associations of apolipoprotein B with pulse pressure and glucose in Chinese families with familial combined hyperlipidemia
W Pei, Y Sun, Q Liu, W Zheng, J Zhang, C Zhang, J Gong, PN Hopkins, R Hui, L Liu, Y Yang
International Journal of Cardiology 2007
Apolipoprotein B is associated with metabolic syndrome in Chinese families with familial combined hyperlipidemia, familial hypertriglyceridemia and familial hypercholesterolemia
W Pei, Y Sun, B Lu, Q Liu, C Zhang, J Zhang, Y Jia, Z Lu, R Hui, L Liu, Y Yang
International Journal of Cardiology 2007
Premature coronary artery disease and apolipoprotein B and apolipoprotein A-I
AF Ayyobi, A Zambon, JD Brunzell
International Congress Series 2007
Haplotype analyses of the APOA5 gene in patients with familial combined hyperlipidemia
GM van der Vleuten, A Isaacs, WW Zeng, E Avest, PJ Talmud, GM Dallinga-Thie, CM van Duijn, AF Stalenhoef, J Graaf
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 2007
Comprehensive Management of High Risk Cardiovascular Patients
N Kopyt
Comprehensive Management of High Risk Cardiovascular Patients 2007
Cardiovascular Medicine
JT Willerson, HJ Wellens, JN Cohn, DR Holmes
2007
High Plasma Level of Remnant-Like Particles Cholesterol in Familial Combined Hyperlipidemia
J de Graaf, GM van der Vleuten, E ter Avest, GM Dallinga-Thie, AF Stalenhoef
The Journal of clinical endocrinology and metabolism 2007
Hypolipidemic Effects of Biopolymers Extracted from Culture Broth, Mycelia, and Fruiting Bodies of Auricularia auricula-judae in Dietary-induced Hyperlipidemic Rats.
Jeong H, Yang BK, Jeong YT, Kim GN, Jeong YS, Kim SM, Mehta P, Song CH
Mycobiology 2007
Unraveling the complex genetics of familial combined hyperlipidemia
E Suviolahti, HE Lilja, P Pajukanta
Annals of Medicine 2006
A moderate-fat diet for combined hyperlipidemia and metabolic syndrome
RH Knopp, B Fish, A Dowdy, B Retzlaff, C Walden, I Rusanu, P Paramsothy
Current Atherosclerosis Reports 2006
Encyclopedia of Molecular Cell Biology and Molecular Medicine
E Beutler
Encyclopedia of Molecular Cell Biology and Molecular Medicine 2006
Clinical trials report
RH Knopp, P Paramsothy
Current Atherosclerosis Reports 2006
The lipoprotein lipase gene in combined hyperlipidemia: evidence of a protective allele depletion
SF Wung, MV Kulkarni, CR Pullinger, MJ Malloy, JP Kane, BE Aouizerat
Lipids in Health and Disease 2006
Impaired endothelium-dependent vascular reactivity in patients with familial combined hyperlipidaemia
MD Michele, A Iannuzzi, A Salvato, P Pauciullo, M Gentile, G Iannuzzo, S Panico, A Pujia, GM Bond, P Rubba
Heart (British Cardiac Society) 2006
Recurrent acute pancreatitis in a patient with type IIb hyperlipoproteinemia: a case report and review of the literature in Korea
BK Kim, MJ Kim, WC Chang, KH Yoo, YG Shin, CH Chung
Yonsei Medical Journal 2006
The Importance of Written Information Packages in Support of Case-Finding Within Families at Risk for Inherited High Cholesterol
HW Nieuwenhoff, I Mesters, JJ Nellissen, AF Stalenhoef, NK Vries
Journal of Genetic Counseling 2006
Hiperlipidemia familiar combinada, síndrome metabólico y enfermedad cardiovascular
S Martinez-Hervás, JT Real, A Priego, J Sanz, JM Martín, R Carmena, JF Ascaso
Revista Española de Cardiología 2006
Genetics of apolipoprotein B and apolipoprotein AI and premature coronary artery disease
A Zambon, BG Brown, SS Deeb, JD Brunzell
Journal of Internal Medicine 2006
Genetic susceptibility to coronary artery disease: from promise to progress
H Watkins, M Farrall
Nature Reviews Genetics 2006
Genetics of familial combined hyperlipidemia
J Naukkarinen, C Ehnholm, L Peltonen
Current Opinion in Lipidology 2006
HEPATOPROTECTIVE AND HYPOLIPIDAEMIC EFFECTS OF GLYCOPROTEIN ISOLATED FROM GARDENIA JASMINOIDES ELLIS IN MICE
SJ Lee, PS Oh, KT Lim
Clinical and Experimental Pharmacology and Physiology 2006
Apolipoprotein E Polymorphism Influences Lipid Phenotypes in Chinese Families With Familial Combined Hyperlipidemia
WD Pei, YH Zhang, YH Sun, YC Gu, YF Wang, CY Zhang, J Zhang, LS Liu, RT Hui, YQ Liu, YJ Yang
Circulation Journal 2006
Genetics of familial combined hyperlipidemia:
J Naukkarinen, C Ehnholm, L Peltonen
Current Opinion in Lipidology 2006
Case Studies in Lipid Management: the case of triglycerides
M Cabezas, T Rabelink
Case Studies in Lipid Management: the case of triglycerides 2006
Case Studies in Lipid Management
J Burnett, G Watts
Case Studies in Lipid Management: the case of triglycerides 2006
Familial Combined Hyperlipidemia, Metabolic Syndrome and Cardiovascular Disease
S Martinez-Hervás, JT Real, A Priego, J Sanz, JM Martín, R Carmena, JF Ascaso
Revista Española de Cardiología (English Edition) 2006
Apolipoprotein A1 and B
AD Sniderman, SM Marcovina
Clinics in Laboratory Medicine 2006
Common Hepatic Nuclear Factor-4  Variants Are Associated With High Serum Lipid Levels and the Metabolic Syndrome
D Weissglas-Volkov, A Huertas-Vazquez, E Suviolahti, J Lee, C Plaisier, S Canizales-Quinteros, T Tusie-Luna, C Aguilar-Salinas, MR Taskinen, P Pajukanta
Diabetes 2006
Case Studies in Lipid Management: a feature of insulin resistance, dyslipidemia and atherosclerosis?
D Müller-Wieland
Case Studies in Lipid Management: a feature of insulin resistance, dyslipidemia and atherosclerosis? 2006
Genomic characterization of five deletions in the LDL receptor gene in Danish Familial Hypercholesterolemic subjects
PH Nissen, D Damgaard, A Stenderup, GG Nielsen, ML Larsen, O Færgeman
BMC Medical Genetics 2006
Heritability and genetic loci of fatty liver in familial combined hyperlipidemia
MC Brouwers, RM Cantor, N Kono, J Yoon, CJ van der Kallen, MA Bilderbeek-Beckers, MM van Greevenbroek, AJ Lusis, TW de Bruin
Journal of lipid research 2006
The involvement of upstream stimulatory factor 1 in Dutch patients with familial combined hyperlipidemia
GM van der Vleuten, A Isaacs, A Hijmans, CM van Duijn, AF Stalenhoef, J Graaf
Journal of lipid research 2006
Characterization of Cq3, a Quantitative Trait Locus that Controls Plasma Cholesterol and Phospholipid Levels in Mice
J SUTO
Journal of Veterinary Medical Science 2006
A Functional Polymorphism in the Glucocorticoid Receptor Gene and Its Relation to Cardiovascular Disease Risk in Familial Hypercholesterolemia
KC Koeijvoets, EF van Rossum, GM Dallinga-Thie, EW Steyerberg, JC Defesche, JJ Kastelein, SW Lamberts, EJ Sijbrands
The Journal of clinical endocrinology and metabolism 2006
The Importance of Written Information Packages in Support of Case-Finding Within Families at Risk for Inherited High Cholesterol
HW van den Nieuwenhoff, I Mesters, JJ Nellissen, AF Stalenhoef, NK de Vries
Journal of Genetic Counseling 2006
USF1 and dyslipidemias: converging evidence for a functional intronic variant
J Naukkarinen, M Gentile, A Soro-Paavonen, J Saarela, HA Koistinen, P Pajukanta, MR Taskinen, L Peltonen
Human Molecular Genetics 2005
Pathophysiology of dyslipidaemia in the metabolic syndrome
GD Kolovou, KK Anagnostopoulou, DV Cokkinos
Postgraduate medical journal 2005
Treatment of dyslipidemia in children and adolescents
KW Holmes, PO Kwiterovich
Current Cardiology Reports 2005
Up‐regulation of CD36/FAT in preadipocytes in familial combined hyperlipidemia
SJ Meex, CJ Kallen, MM Greevenbroek, PM Eurlings, ME Hasnaoui, CT Evelo, PJ Lindsey, JJ Luiken, JF Glatz, TW Bruin
The FASEB Journal 2005
A SCIENCE OF THE INDIVIDUAL: Implications for a Medical School Curriculum
B Childs, C Wiener, D Valle
Annual Review of Genomics and Human Genetics 2005
Characterisation of the lipoprotein structure in the St. Thomas’ Mixed Hyperlipidaemic (SMHL) rabbit
B Roos, MJ Caslake, K Milliner, GM Benson, KE Suckling, CJ Packard
Atherosclerosis 2005
Genome scan for quantitative trait loci influencing HDL levels: evidence for multilocus inheritance in familial combined hyperlipidemia
F Gagnon, GP Jarvik, MD Badzioch, AG Motulsky, JD Brunzell, EM Wijsman
Human Genetics 2005
Upstream stimulatory factor 1 associated with familial combined hyperlipidemia, LDL cholesterol, and triglycerides
H Coon, Y Xin, PN Hopkins, RM Cawthon, SJ Hasstedt, SC Hunt
Human Genetics 2005
Antihyperlipidemic Effect of Crocin Isolated from the Fructus of Gardenia jasminoides and Its Metabolite Crocetin
IA Lee, JH Lee, NI Baek, DH Kim
Biological & Pharmaceutical Bulletin 2005
Effect of statins on LDL particle size in patients with familial combined hyperlipidemia: a comparison between atorvastatin and pravastatin
CR Sirtori, L Calabresi, L Pisciotta, L Cattin, P Pauciullo, M Montagnani, E Manzato, GB Bon, R Fellin
Nutrition, Metabolism and Cardiovascular Diseases 2005
Hiperlipemia familiar combinada. Criterios diagnósticos y terapéuticos
EM Ibarra, PM Fuentes, FC Murillo
Clínica e Investigación en Arteriosclerosis 2005
Visión actualizada de la hiperlipidemia familiar combinada aplicada a la mejora de su diagnóstico
J Ribalta, M Castro-Cabezas, N Plana, L Masana
Clínica e Investigación en Arteriosclerosis 2005
Soluble cell adhesion molecules s-vcam-1 and s-icam-1 in subjects with familial combined hyperlipidemia
D Karasek, H Vaverkova, M Halenka, M Budikova, D Novotny
Biomedical Papers 2005
Thematic review series: The Pathogenesis of Atherosclerosis. An interpretive history of the cholesterol controversy, part III: mechanistically defining the role of hyperlipidemia
D Steinberg
Journal of lipid research 2005
Lipid Profile of Children with a Family History of Coronary Heart Disease or Hyperlipidemia: 9-Year Experience of an Outpatient Clinic for the Prevention of Cardiovascular Diseases
A Makedou, M Kourti, K Makedou, S Lazaridou, G Varlamis
Angiology 2005
Multiple QTLs influencing triglyceride and HDL and total cholesterol levels identified in families with atherogenic dyslipidemia
Y Yu, DF Wyszynski, DM Waterworth, SD Wilton, PJ Barter, YA Kesäniemi, RW Mahley, R McPherson, G Waeber, TP Bersot, Q Ma, SS Sharma, DS Montgomery, LT Middleton, SS Sundseth, V Mooser, SM Grundy, LA Farrer
Journal of lipid research 2005
150kDa glycoprotein isolated from Solanum nigrum Linne enhances activities of detoxicant enzymes and lowers plasmic cholesterol in mouse
SJ Lee, JH Ko, K Lim, KT Lim
Pharmacological research : the official journal of the Italian Pharmacological Society 2005
Signaling Pathways in Liver Diseases
JF Dufour, PA Clavien, C Trautwein, R Graf
2005
Rat model of familial combined hyperlipidemia as a result of comparative mapping
T Ueno, J Tremblay, J Kunes, J Zicha, Z Dobesova, Z Pausova, AY Deng, YL Sun, HJ Jacob, P Hamet
Physiological genomics 2004
Blasts from the past
PA Insel, S Kornfeld, PW Majerus, AR Marks, PA Marks, AS Relman, BF Scharschmidt, TP Stossel, AP Varki, SJ Weiss, JD Wilson
Journal of Clinical Investigation 2004
Reflecting on 80 years of excellence
U Savla
Journal of Clinical Investigation 2004
Pharmacological modulation of cholesteryl ester transfer protein, a new therapeutic target in atherogenic dyslipidemia
WL Goff, M Guerin, MJ Chapman
Pharmacology & Therapeutics 2004
Management of atherogenic dyslipidemia of the metabolic syndrome: evolving rationale for combined drug therapy
GL Vega
Endocrinology & Metabolism Clinics of North America 2004
Associations between HDL oxidation and paraoxonase-1 and paraoxonase-1 gene polymorphisms in families affected by familial combined hyperlipidemia
ML Liu, RW James, K Ylitalo, MR Taskinen
Nutrition, Metabolism and Cardiovascular Diseases 2004
Increased circulating malondialdehyde-modified LDL in the patients with familial combined hyperlipidemia and its relation with the hepatic lipase activity
K Yamazaki, H Bujo, K Taira, N Itou, M Shibasaki, K Takahashi, Y Saito
Atherosclerosis 2004
TXNIP gene not associated with familial combined hyperlipidemia in the NHLBI Family Heart Study
H Coon, N Singh, D Dunn, JH Eckfeldt, MA Province, PN Hopkins, R Weiss, SC Hunt, MF Leppert
Atherosclerosis 2004
Contribution of Chromosome 1q21-q23 to Familial Combined Hyperlipidemia in Mexican Families
A Huertas-Vázquez, JP Rincón, S Canizales-Quinteros, L Riba, G Vega-Hernández, S Ramírez-Jiménez, M Aurón-Gómez, FJ Gómez-Pérez, CA Aguilar-Salinas, MT Tusié-Luna
Annals of Human Genetics 2004
Statin myotoxicity is associated with changes in the cardiopulmonary function
PS Phillips, CT Phillips, MJ Sullivan, RK Naviaux, RH Haas
Atherosclerosis 2004
5-Hydroxy-7-(4′-hydroxy-3′-methoxyphenyl)-1-phenyl-3-heptanone: A Pancreatic Lipase Inhibitor Isolated from Alpinia officinarum
JE Shin, MJ Han, MC Song, NI Baek, DH Kim
Biological & Pharmaceutical Bulletin 2004
Apolipoprotein B as a Marker of Familial Hyperlipoproteinemia
T Sveger, K Nordborg
Journal of Atherosclerosis and Thrombosis 2004
An ω-3 polyunsaturated fatty acid concentrate increases plasma high-density lipoprotein 2 cholesterol and paraoxonase levels in patients with familial combined hyperlipidemia
L Calabresi, B Villa, M Canavesi, CR Sirtori, RW James, F Bernini, G Franceschini
Metabolism 2004
Hypolipidemic effect of different extracts of Clerodendron colebrookianum Walp in normal and high-fat diet fed rats
R Devi, DK Sharma
Journal of Ethnopharmacology 2004
Hiperlipidemias: concepto, clasificación y mecanismo etiopatogénico. Hiperlipidemias primarias
MP Mieras, PM Alonso, PC Gómez
Medicine - Programa de Formación Médica Continuada Acreditado 2004
Diagnóstico y tratamiento de las hiperlipemias familiares
TM Morató, R Alonso, P Mata
Atención Primaria 2004
How more effective diagnosis of familial combined hyperlipidemia could lead to more effective therapy
AD Sniderman, JC Engert, MC Cabezas
Drug Discovery Today: Disease Mechanisms 2004
Abdominal Obesity and Expression of Familial Combined Hyperlipidemia
CJ van der Kallen, C Voors-Pette, TW de Bruin
Obesity research 2004
Variation in USF1 shows haplotype effects, gene : gene and gene : environment associations with glucose and lipid parameters in the European Atherosclerosis Research Study II
W Putt, J Palmen, V Nicaud, DA Tregouet, N Tahri-Daizadeh, DM Flavell, SE Humphries, PJ Talmud
Human Molecular Genetics 2004
Familial combined hyperlipidemia is associated with upstream transcription factor 1 (USF1)
P Pajukanta, HE Lilja, JS Sinsheimer, RM Cantor, AJ Lusis, M Gentile, XJ Duan, A Soro-Paavonen, J Naukkarinen, J Saarela, M Laakso, C Ehnholm, MR Taskinen, L Peltonen
Nature Genetics 2004
Locus for quantitative HDL-cholesterol on chromosome 10q in Finnish families with dyslipidemia
HE Lilja, E Suviolahti, A Soro-Paavonen, T Hiekkalinna, A Day, K Lange, E Sobel, MR Taskinen, L Peltonen, M Perola, P Pajukanta
Journal of lipid research 2004
Linkage and Association Between Distinct Variants of the APOA1/C3/A4/A5 Gene Cluster and Familial Combined Hyperlipidemia
S Eichenbaum-Voline, M Olivier, EL Jones, RP Naoumova, B Jones, B Gau, HN Patel, M Seed, DJ Betteridge, DJ Galton, EM Rubin, J Scott, CC Shoulders, LA Pennacchio
Arteriosclerosis, thrombosis, and vascular biology 2004
Abdominal Obesity and Dyslipidemia in the Metabolic Syndrome: Importance of Type 2 Diabetes and Familial Combined Hyperlipidemia in Coronary Artery Disease Risk
MC Carr, JD Brunzell
The Journal of clinical endocrinology and metabolism 2004
Atorvastatin and omega-3 fatty acids protect against activation of the coagulation system in patients with combined hyperlipemia
A Nordoy, B Svensson, JB Hansen
Journal of Thrombosis and Haemostasis 2003
Hypercholesterolemia and Dyslipidemia: Issues for the clinician
HR Superko, NA Chronos
Current Treatment Options in Cardiovascular Medicine 2003
Effects of HIV protease inhibitor therapy on lipid metabolism
DY Hui
Progress in Lipid Research 2003
Dyslipidaemia
P Durrington
The Lancet 2003
Combined analysis of genome scans of dutch and finnish families reveals a susceptibility locus for high-density lipoprotein cholesterol on chromosome 16q
P Pajukanta, H Allayee, KL Krass, A Kuraishy, A Soro, HE Lilja, R Mar, MR Taskinen, I Nuotio, M Laakso, JI Rotter, TW de Bruin, RM Cantor, AJ Lusis, L Peltonen
The American Journal of Human Genetics 2003
Intra-individual variations of fasting plasma lipids, apolipoproteins and postprandial lipemia in familial combined hyperlipidemia compared to controls
D Delawi, S Meijssen, MC Cabezas
Clinica Chimica Acta 2003
3-Methylethergalangin Isolated from Alpinia officinarum Inhibits Pancreatic Lipase
JE Shin, MJ Han, DH Kim
Biological & Pharmaceutical Bulletin 2003
Novel microsomal triglyceride transfer protein inhibitors
SJ Williams, JD Best
Expert Opinion on Therapeutic Patents 2003
Role of stearoyl-coenzyme A desaturase in lipid metabolism
M Miyazaki, JM Ntambi
Prostaglandins, Leukotrienes and Essential Fatty Acids 2003
Screening for Familial Combined Hyperlipidemia in Children Using Lipid Phenotypes
F Iwata, T Okada, Y Kuromori, M Hara, K Harada
Journal of Atherosclerosis and Thrombosis 2003
Leptin receptor polymorphism is associated with serum lipid levels and impairment of cholesterol lowering effect by simvastatin in Japanese men
A Takahashi-Yasuno, H Masuzaki, T Miyawaki, Y Ogawa, N Matsuoka, T Hayashi, K Hosoda, G Inoue, Y Yoshimasa, K Nakao
Diabetes Research and Clinical Practice 2003
Genetic disorders of lipoprotein transport in children
SB Clauss, PO Kwiterovich
Progress in Pediatric Cardiology 2003
Lipoprotein distribution in the metabolic syndrome, type 2 diabetes mellitus, and familial combined hyperlipidemia
AF Ayyobi, JD Brunzell
The American Journal of Cardiology 2003
Lung Biology in Health and Disease
N Zamel
Lung Biology in Health and Disease: Experimental Models and Therapeutic Potential 2003
Familial hypercholesterolemia—Improving treatment and meeting guidelines
PN Hopkins
International Journal of Cardiology 2003
Disturbed regulation of cholesterol synthesis in monocytes of obese patients with hypercholesterolemia
G Paragh, Z Balogh, E Kovács, M Szabolcs, J Szabó, K Csapó, G Fóris
Metabolism 2003
Determinants of low HDL levels in familial combined hyperlipidemia
A Soro, M Jauhiainen, C Ehnholm, MR Taskinen
Journal of lipid research 2003
Effects of atorvastatin on fasting and postprandial complement component 3 response in familial combined hyperlipidemia
C Verseyden, S Meijssen, H Dijk, H Jansen, MC Cabezas
Journal of lipid research 2003
Genome-wide scan for quantitative trait loci influencing LDL size and plasma triglyceride in familial hypertriglyceridemia
MA Austin, KL Edwards, SA Monks, KM Koprowicz, JD Brunzell, AG Motulsky, MC Mahaney, JE Hixson
Journal of lipid research 2003
Xanthoma of Bone: First Sign of Hyperlipidemia Type IIB: A Case Report
D Dallari, A Marinelli, A Pellacani, L Valeriani, C Lesi, F Bertoni, A Giunti
Clinical Orthopaedics and Related Research® 2003
Atherosclerosis, Hypertension and Diabetes
GN Pierce, M Nagano, P Zahradka, NS Dhalla
2003
Atlas of Atherosclerosis
PW Wilson
2003
Evidence of linkage of HDL level variation to APOC3 in two samples with different ascertainment
F Gagnon, GP Jarvik, AG Motulsky, SS Deeb, JD Brunzell, EM Wijsman
Human Genetics 2003
A mission statement for the JCI at the dawn of the 21st Century
Andrew Marks
Journal of Clinical Investigation 2002
Report of the Japan Atherosclerosis Society (JAS) Guideline for Diagnosis and Treatment of Hyperlipidemia in Japanese Adults
Y Hata, H Mabuchi, Y Saito, H Itakura, G Egusa, H Ito, T Teramoto, M Tsushima, N Tada, S Oikawa, N Yamada, S Yamashita, N Sakuma, J Sasaki
Journal of Atherosclerosis and Thrombosis 2002
Dyslipidemia in young Japanese children: its relation to familial hypercholesterolemiaand familial combined hyperlipidemia
T Ohta, K Kiwaki, F Endo, H Umehashi, I Matsuda
Pediatrics International 2002
Mouse Models of Atherosclerosis
A Daugherty
The American Journal of the Medical Sciences 2002
Getting insurance after genetic screening on familial hypercholesterolaemia; the need to educate both insurers and the public to increase adherence to national guidelines in The Netherlands
PJ de Mheen, MC van Maarle, ME Stouthard
Journal of epidemiology and community health 2002
Metabolic pathogenesis of familial combined hyperlipidaemia with emphasis on insulin resistance, adipose tissue metabolism and free fatty acids
J Graaf, MJ Veerkamp, AF Stalenhoef
Journal of the Royal Society of Medicine 2002
Relationship inference from trios of individuals, in the presence of typing error
SK Sieberts, EM Wijsman, EA Thompson
The American Journal of Human Genetics 2002
Reduced structural and functional skin capillaries in familial combined hyperlipidemia affected men, associated with increased remnant-like lipoprotein cholesterol levels
ET Keulen, NC Schaper, AJ Houben, JM van Lin, I Lutgens, K Rijkers, GM Dallinga-Thie, TW de Bruin
Atherosclerosis 2002
Carotid artery intima-media thickness in Finnish families with familial combined hyperlipidemia
K Ylitalo, M Syvänne, R Salonen, I Nuotio, MR Taskinen, JT Salonen
Atherosclerosis 2002
Identification of the PPARA locus on chromosome 22q13.3 as a modifier gene in familial combined hyperlipidemia
PM Eurlings, CJ van der Kallen, JM Geurts, DM Flavell, TW de Bruin
Molecular Genetics and Metabolism 2002
Daio-Orengedokuto Inhibits HMG-CoA Reductase and Pancreatic Lipase
YS Kim, EA Jung, JE Shin, JC Chang, HK Yang, NJ Kim, KH Cho, HS Bae, SK Moon, DH Kim
Biological & Pharmaceutical Bulletin 2002
Risk perception of participants in a family-based genetic screening program on familial hypercholesterolemia
MC Maarle, ME Stouthard, GJ Bonsel
American Journal of Medical Genetics 2002
Heritabilities of Apolipoprotein and Lipid Levels in Three Countries
M Beekman, BT Heijmans, NG Martin, NL Pedersen, JB Whitfield, U DeFaire, GC van Baal, H Snieder, GP Vogler, PE Slagboom, DI Boomsma
Twin Research and Human Genetics 2002
An Internist???s Update on Cholesterol Management
HE Holman, GS Hicks, AK Low, MJ Bouldin, LD Russell, CA Friedrich, CA Brown
The American Journal of the Medical Sciences 2002
Familial Combined Hyperlipidemia (FCHL) in Children: The Significance of Early Development of HyperapoB Lipoproteinemia, Obesity and Aging
Y Kuromori, T Okada, F Iwata, M Hara, N Noto, K Harada
Journal of Atherosclerosis and Thrombosis 2002
A proposal to redefine familial combined hyperlipidaemia - Third workshop on FCHL held in Barcelona from 3 to 5 May 2001, during the Scientific Sessions of the European Society for Clinical Investigation
AD Sniderman, MC Cabezas, J Ribalta, R Carmena, TW de Bruin, J Graaf, DW Erkelens, SE Humphries, L Masana, JT Real, PJ Talmud, MR Taskinen
European Journal of Clinical Investigation 2002
Recognition of familial dyslipidemias in 5-year-old children using the lipid phenotypes of parents
J Lapinleimu, IO Nuotio, H Lapinleimu, OG Simell, L Rask-Nissilä, JS Viikari
Atherosclerosis 2002
contribution of major cardiovascular risk factors to familial premature coronary artery disease
V Jomini, S Oppliger-Pasquali, V Wietlisbach, N Rodondi, V Jotterand, F Paccaud, R Darioli, P Nicod, V Mooser
Journal of the American College of Cardiology 2002
N-3 fatty acids and diabetes
CR Sirtori, C Galli
Biomedicine & Pharmacotherapy 2002
Angptl3 regulates lipid metabolism in mice
R Koishi, Y Ando, M Ono, M Shimamura, H Yasumo, T Fujiwara, H Horikoshi, H Furukawa
Nature Genetics 2002
Clinical relevance of the biochemical, metabolic, and genetic factors that influence low-density lipoprotein heterogeneity
PO Kwiterovich
The American Journal of Cardiology 2002
Combination therapy for combined dyslipidemia
AM Xydakis, CM Ballantyne
The American Journal of Cardiology 2002
Genetic influences contributing to LDL particle size in familial combined hyperlipidaemia
J Vakkilainen, P Pajukanta, RM Cantor, IO Nuotio, S Lahdenperä, K Ylitalo, J Pihlajamäki, PT Kovanen, M Laakso, JS Viikari, L Peltonen, MR Taskinen
European Journal of Human Genetics 2002
Relationship between stearoyl-CoA desaturase activity and plasma triglycerides in human and mouse hypertriglyceridemia
AD Attie, RM Krauss, MP Gray-Keller, A Brownlie, M Miyazaki, JJ Kastelein, AJ Lusis, AF Stalenhoef, JP Stoehr, MR Hayden, JM Ntambi
Journal of lipid research 2002
Hypertriglyceridemia: A Review Beyond Low-Density Lipoprotein:
RJ Rapp
Cardiology in Review 2002
Locus for Elevated Apolipoprotein B Levels on Chromosome 1p31 in Families With Familial Combined Hyperlipidemia
H Allayee, KL Krass, P Pajukanta, R M., CJ van der Kallen, R Mar, JI Rotter, TW de Bruin, L Peltonen, AJ Lusis
Circulation research 2002
Diagnosis of Familial Combined Hyperlipidemia Based on Lipid Phenotype Expression in 32 Families: Results of a 5-Year Follow-Up Study
MJ Veerkamp, J de Graaf, SJ Bredie, JC Hendriks, PN Demacker, AF Stalenhoef
Arteriosclerosis, thrombosis, and vascular biology 2002
Increased Intima-Media Thickness in Familial Combined Hyperlipidemia Associated With Apolipoprotein B
ET Keulen, M Kruijshoop, NC Schaper, AP Hoeks, TW de Bruin
Arteriosclerosis, thrombosis, and vascular biology 2002
Delayed and Exaggerated Postprandial Complement Component 3 Response in Familial Combined Hyperlipidemia
S Meijssen, H van Dijk, C Verseyden, DW Erkelens, MC Cabezas
Arteriosclerosis, thrombosis, and vascular biology 2002
Association Between Carotid Intima-Media Thickness and Low-Density Lipoprotein Size and Susceptibility of Low-Density Lipoprotein to Oxidation in Asymptomatic Members of Familial Combined Hyperlipidemia Families
ML Liu, K Ylitalo, I Nuotio, R Salonen, JT Salonen, MR Taskinen
Stroke; a journal of cerebral circulation 2002
In Vivo Modulation of Plasma Free Fatty Acids in Patients with Familial Combined Hyperlipidemia Using Lipid-Lowering Medication
S Meijssen, RJ Derksen, S Bilecen, DW Erkelens, MC Cabezas
The Journal of clinical endocrinology and metabolism 2002
Postprandial changes of apoB-100 and apoB-48 in TG rich lipoproteins in familial combined hyperlipidemia
C Verseyden, S Meijssen, MC Cabezas
Journal of lipid research 2002
LDL particle size in familial combined hyperlipidemia: effects of serum lipids, lipoprotein-modifying enzymes, and lipid transfer proteins
J Vakkilainen, M Jauhiainen, K Ylitalo, IO Nuotio, JS Viikari, C Ehnholm, MR Taskinen
Journal of lipid research 2002
Identification of differentially expressed genes in subcutaneous adipose tissue from subjects with familial combined hyperlipidemia
PM Eurlings, CJ van der Kallen, JM Geurts, P Kouwenberg, WD Boeckx, TW de Bruin
Journal of lipid research 2002
Newly Identified Apolipoprotein AV Gene Predisposes to High Plasma Triglycerides in Familial Combined Hyperlipidemia
J Ribalta, L Figuera, J Fernández-Ballart, E Vilella, MC Cabezas, L Masana, J Joven
Clinical chemistry 2002
Two newly identified SNPs in the APO AI-CIII intergenic region are strongly associated with familial combined hyperlipidaemia
M Groenendijk, RM Cantor, H Funke, GM Dallinga-Thie
European Journal of Clinical Investigation 2001
Monogenic Dyslipidemias: Window on Determinants of Plasma Lipoprotein Metabolism
RA Hegele
The American Journal of Human Genetics 2001
Apolipoprotein E genotype and cardiovascular disease in the Framingham Heart Study
C Lahoz, EJ Schaefer, LA Cupples, PW Wilson, D Levy, D Osgood, S Parpos, J Pedro-Botet, JA Daly, JM Ordovas
Atherosclerosis 2001
Lipoprotein(a) as a risk factor for maternal cardiovascular disease mortality in kindreds with familial combined hyperlipidemia or familial hypertriglyceridemia
H Kim, SM Marcovina, KL Edwards, B McKnight, CM Bradley, MJ McNeely, BM Psaty, AG Motulsky, MA Austin
Clinical Genetics 2001
Insulin resistance in the St. Thomas' mixed hyperlipidaemic (SMHL) rabbit, a model for familial combined hyperlipidaemia
B Roos
Atherosclerosis 2001
Genetic Dissection of Familial Combined Hyperlipidemia
PM Eurlings, CJ van der Kallen, JM Geurts, MM van Greevenbroek, TW de Bruin
Molecular Genetics and Metabolism 2001
Excess coronary heart disease in Familial Combined Hyperlipidemia, in relation to genetic factors and central obesity
C Voors-Pette, TW de Bruin
Atherosclerosis 2001
Lipoprotein and apolipoprotein abnormalities in familial combined hyperlipidemia: a 20-year prospective study
MJ McNeely, KL Edwards, SM Marcovina, JD Brunzell, AG Motulsky, MA Austin
Atherosclerosis 2001
Identification of a common variant in the lipoprotein lipase gene in a large Utah kindred ascertained for coronary heart disease: the −93G/D9N variant predisposes to low HDL-C/high triglycerides
ME Samuels, KC Forbey, JE Reid, V Abkevich, K Bulka, BR Wardell, BR Bowen, PN Hopkins, SC Hunt, DG Ballinger, MH Skolnick, S Wagner
Clinical Genetics 2001
The hormone sensitive lipase gene in familial combined hyperlipidemia and insulin resistance
J Pihlajamaki, R Valve, L Karjalainen, P Karhapaa, I Vauhkonen, M Laakso
European Journal of Clinical Investigation 2001
Coronary Heart Disease, Hypercholesterolemia, and Atherosclerosis I. False Premises
WE Stehbens
Experimental and Molecular Pathology 2001
Coronary Heart Disease, Hypercholesterolemia, and Atherosclerosis II. Misrepresented Data
WE Stehbens
Experimental and Molecular Pathology 2001
Effectiveness of high doses of simvastatin as monotherapy in mixed hyperlipidemia
M Miller, C Dolinar, W Cromwell, JD Otvos
The American Journal of Cardiology 2001
Pediatric Gastroenterology and Nutrition in Clinical Practice
B Stoll, D Burrin
Pediatric Gastroenterology and Nutrition in Clinical Practice 2001
Hyperlipidemia in children and adolescents
AM Valente, JW Newburger, RM Lauer
American Heart Journal 2001
Erratum: Apolipoprotein B secretion and atherosclerosis are decreased in mice with phospholipid-transfer protein deficiency
XC Jiang, S Qin, C Qiao, K Kawano, M Lin, A Skold, X Xiao, AR Tall
Nature Medicine 2001
Relationship of Insulin Sensitivity and ApoB Levels to Intra-abdominal Fat in Subjects With Familial Combined Hyperlipidemia
JQ Purnell, SE Kahn, RS Schwartz, JD Brunzell
Arteriosclerosis, thrombosis, and vascular biology 2001
Familial Combined Hyperlipidemia and Insulin Resistance: Distant Relatives Linked by Intra-abdominal Fat?
RH Eckel
Arteriosclerosis, thrombosis, and vascular biology 2001
Analysis of the Ileal Bile Acid Transporter Gene, SLC10A2 , in Subjects With Familial Hypertriglyceridemia
MW Love, AL Craddock, B Angelin, JD Brunzell, WC Duane, PA Dawson
Arteriosclerosis, thrombosis, and vascular biology 2001
Genome Scan for Blood Pressure in Dutch Dyslipidemic Families Reveals Linkage to a Locus on Chromosome 4p
H Allayee, TW de Bruin, KM Dominguez, LS Cheng, E Ipp, R M., KL Krass, ET Keulen, BE Aouizerat, AJ Lusis, JI Rotter
Hypertension 2001
Positional cloning of the combined hyperlipidemia gene Hyplip1
JS Bodnar, A Chatterjee, LW Castellani, DA Ross, J Ohmen, J Cavalcoli, C Wu, KM Dains, J Catanese, M Chu, SS Sheth, K Charugundla, P Demant, DB West, P de Jong, AJ Lusis
Nature Genetics 2001
New genetic variants in the apoA-I and apoC-III genes and familial combined hyperlipidemia
M Groenendijk, R M., TW Bruin, GM Dallinga-Thie
Journal of lipid research 2001
Hypercholesterolemia and dyslipidemia
HR Superko
Current Treatment Options in Cardiovascular Medicine 2000
Lipid metabolism
J Stocks
Current Opinion in Lipidology 2000
GENETICS OFLIPOPROTEINABNORMALITIESASSOCIATED WITHCORONARYHEARTDISEASESUSCEPTIBILITY
JL Breslow
Annual Review of Genetics 2000
Evidence of Linkage of Familial Hypoalphalipoproteinemia to a Novel Locus on Chromosome 11q23
EN Kort, DG Ballinger, W Ding, SC Hunt, BR Bowen, V Abkevich, K Bulka, B Campbell, C Capener, A Gutin, K Harshman, M McDermott, T Thorne, H Wang, B Wardell, J Wong, PN Hopkins, M Skolnick, M Samuels
The American Journal of Human Genetics 2000
Omacor in familial combined hyperlipidemia: effects on lipids and low density lipoprotein subclasses
L Calabresi, D Donati, F Pazzucconi, CR Sirtori, G Franceschini
Atherosclerosis 2000
Reduced hormone-sensitive lipase activity is not a major metabolic defect in Finnish FCHL families
K Ylitalo, V Large, P Pajukanta, S Reynisdottir, KV Porkka, J Vakkilainen, I Nuotio, MR Taskinen, P Arner
Atherosclerosis 2000
Hereditary dyslipidemias and combined risk factors in children with a family history of premature coronary artery disease
T Sveger, CE Flodmark, K Nordborg, P Nilsson-Ehle, N Borgfors
Archives of disease in childhood 2000
One-Year Effects of Increasingly Fat-Restricted, Carbohydrate-Enriched Diets on Lipoprotein Levels in Free-Living Subjects
RH Knopp, B Retzlaff, C Walden, B Fish, B Buck, B McCann
Proceedings of the Society for Experimental Biology and Medicine 2000
Triglyceride, small, dense low-density lipoprotein, and the atherogenic lipoprotein phenotype
MA Austin
Current Atherosclerosis Reports 2000
Les dyslipoprotéinémies athérogènes
G Turpin, E Bruckert, P Giral
Annales de l'Institut Pasteur/Actualités 2000
Comparison of the measurement of lipids and lipoproteins versus assay of apolipoprotein B for estimation of coronary heart disease risk: a study in familial combined hyperlipidemia
PN Demacker, MJ Veerkamp, SJ Bredie, SM Marcovina, J Graaf, AF Stalenhoef
Atherosclerosis 2000
The V73M mutation in the hepatic lipase gene is associated with elevated cholesterol levels in four Dutch pedigrees with familial combined hyperlipidemia
MJ Hoffer, H Snieder, SJ Bredie, PN Demacker, JJ Kastelein, RR Frants, AF Stalenhoef
Atherosclerosis 2000
Introduction: Low-Saturated Fat, High-Carbohydrate Diets: Effects on Triglyceride and LDL Synthesis, the LDL Receptor, and Cardiovascular Disease Risk
RH Knopp
Proceedings of the Society for Experimental Biology and Medicine 2000
Support for linkage of familial combined hyperlipidemia to chromosome 1q21-q23 in Chinese and German families
W Pei, H Baron, B Müller-Myhsok, H Knoblauch, SA Al-Yahyaee, R Hui, X Wu, L Liu, A Busjahn, FC Luft, H Schuster
Clinical Genetics 2000
Hypocholesterolemic effects of crude extract of leaf of Moringa oleifera Lam in high-fat diet fed wistar rats
S Ghasi, E Nwobodo, JO Ofili
Journal of Ethnopharmacology 2000
Hypertriglyceridemia and Low High-Density Lipoprotein: Risks for Coronary Artery Disease?:
C Lamendola
The Journal of cardiovascular nursing 2000
Prevention of coronary heart disease
PR Liebson, EA Amsterdam
Disease-a-Month 2000
Preventing, stopping, or reversing coronary artery disease— triglyceride-rich lipoproteins and associated lipoprotein and metabolic abnormalities: The need for recognition and treatment
EE Ferguson
Disease-a-Month 2000
Governance of the concentration of plasma LDL: a reevaluation of the LDL receptor paradigm
A D Sniderman, X J Zhang, K Cianflone
Atherosclerosis 2000
Genome scan for adiposity in Dutch dyslipidemic families reveals novel quantitative trait loci for leptin, body mass index and soluble tumor necrosis factor receptor superfamily 1A
CJ der Kallen, RM Cantor, MM Greevenbroek, JM Geurts, FG Bouwman, BE Aouizerat, H Allayee, WA Buurman, AJ Lusis, JI Rotter, TW Bruin
International Journal of Obesity 2000
Cardiovascular risk factors and testing of relatives amongst patients with familial hyperlipidaemia one decade after a clinical trial
S Tonstad, I Hjermann
Journal of Internal Medicine 2000
Effect of ω-3 Fatty Acids and Simvastatin on Hemostatic Risk Factors and Postprandial Hyperlipemia in Patients With Combined Hyperlipemia
A Nordøy, KH Bønaa, PM Sandset, JB Hansen, H Nilsen
Arteriosclerosis, thrombosis, and vascular biology 2000
Impaired Free Fatty Acid Suppression During Hyperinsulinemia Is a Characteristic Finding in Familial Combined Hyperlipidemia, but Insulin Resistance Is Observed Only in Hypertriglyceridemic Patients
J Pihlajamäki, L Karjalainen, P Karhapää, I Vauhkonen, M Laakso
Arteriosclerosis, thrombosis, and vascular biology 2000
Cardiovascular Disease Mortality in Familial Forms of Hypertriglyceridemia: A 20-Year Prospective Study
MA Austin, B McKnight, KL Edwards, CM Bradley, MJ McNeely, BM Psaty, JD Brunzell, AG Motulsky
Circulation 2000
Replication of Linkage of Familial Combined Hyperlipidemia to Chromosome 1q With Additional Heterogeneous Effect of Apolipoprotein A-I/C-III/A-IV Locus: The NHLBI Family Heart Study
H Coon, RH Myers, IB Borecki, DK Arnett, SC Hunt, MA Province, L Djousse, MF Leppert
Arteriosclerosis, thrombosis, and vascular biology 2000
Genetic Localization to Chromosome 1p32 of the Third Locus for Familial Hypercholesterolemia in a Utah Kindred
SC Hunt, PN Hopkins, K Bulka, MT McDermott, TL Thorne, BB Wardell, BR Bowen, DG Ballinger, MH Skolnick, ME Samuels
Arteriosclerosis, thrombosis, and vascular biology 2000
Prevention Conference V: Beyond Secondary Prevention : Identifying the High-Risk Patient for Primary Prevention : Medical Office Assessment : Writing Group I
SM Grundy, T Bazzarre, J Cleeman, RB DAgostino, M Hill, N Houston-Miller, WB Kannel, R Krauss, HM Krumholz, RM Lauer, IS Ockene, RC Pasternak, T Pearson, PM Ridker, D Wood
Circulation 2000
G-250A Substitution in Promoter of Hepatic Lipase Gene Is Associated With Dyslipidemia and Insulin Resistance in Healthy Control Subjects and in Members of Families With Familial Combined Hyperlipidemia
J Pihlajamäki, L Karjalainen, P Karhapää, I Vauhkonen, MR Taskinen, SS Deeb, M Laakso
Arteriosclerosis, thrombosis, and vascular biology 2000
Lipoprotein Metabolism and Atherogenesis
T Kita, M Yokode
2000
Homocysteine and Vascular Disease
K Robinson
2000
Age-related Increases in Plasma Phosphatidylcholine Hydroperoxide Concentrations in Control Subjects and Patients with Hyperlipidemia
M Kinoshita, S Oikawa, K Hayasaka, A Sekikawa, T Nagashima, T Toyota, T Miyazawa
Clinical chemistry 2000
Expression of human apolipoprotein A-II in apolipoprotein E-deficient mice induces features of familial combined hyperlipidemia
JC Escolà-Gil, J Julve, À Marzal-Casacuberta, J Ordóñez-Llanos, F González-Sastre, F Blanco-Vaca
Journal of lipid research 2000
In vivo evidence of defective postprandial and postabsorptive free fatty acid metabolism in familial combined hyperlipidemia
S Meijssen, MC Cabezas, TB Twickler, H Jansen, DW Erkelens
Journal of lipid research 2000
Two novel mutations in the lipoprotein lipase gene in a family with marked hypertriglyceridemia in heterozygous carriers: potential interaction with the polymorphic marker D1S104 on chromosome 1q21–q23
B Hölzl, HG Kraft, H Wiebusch, A Sandhofer, J Patsch, F Sandhofer, B Paulweber
Journal of lipid research 2000
Contribution of the hepatic lipase gene to the atherogenic lipoprotein phenotype in familial combined hyperlipidemia
H Allayee, KM Dominguez, BE Aouizerat, RM Krauss, JI Rotter, J Lu, R M., TW de Bruin, AJ Lusis
Journal of lipid research 2000
Insulin resistance and familial dyslipidaemias
JF Ascaso, JT Real, R Carmena
Diabetes, Obesity and Metabolism 1999
PlA1/A2 polymorphism of platelet glycoprotein IIIa and risk of acute coronary syndromes in heterozygous familial hypercholesterolemia
A Cenarro, E Casao, F Civeira, HK Jensen, O Færgeman, M Pocovı́
Atherosclerosis 1999
Novel genes for familial combined hyperlipidemia
BE Aouizerat, H Allayee, J Bodnar, KL Krass, L Peltonen, TW de Bruin, JI Rotter, AJ Lusis
Current Opinion in Lipidology 1999
Genomewide Scan for Familial Combined Hyperlipidemia Genes in Finnish Families, Suggesting Multiple Susceptibility Loci Influencing Triglyceride, Cholesterol, and Apolipoprotein B Levels
P Pajukanta, JD Terwilliger, M Perola, T Hiekkalinna, I Nuotio, P Ellonen, M Parkkonen, J Hartiala, K Ylitalo, J Pihlajamäki, K Porkka, M Laakso, J Viikari, C Ehnholm, MR Taskinen, L Peltonen
The American Journal of Human Genetics 1999
A Genome Scan for Familial Combined Hyperlipidemia Reveals Evidence of Linkage with a Locus on Chromosome 11
BE Aouizerat, H Allayee, RM Cantor, RC Davis, CD Lanning, PZ Wen, GM Dallinga-Thie, TW de Bruin, JI Rotter, AJ Lusis
The American Journal of Human Genetics 1999
Genetics of familial combined hyperlipidemia
P Pajukanta, KV Porkka
Current Atherosclerosis Reports 1999
Studies in hypertriglyceridaemia VI: serum lathosterol concentration is raised in hypertriglyceridaemic non-diabetic males with hyperinsulinaemia
A Asplund-Carlson, E Lund, I Bjorkhem, LA Carlson
Journal of Internal Medicine 1999
Joint effects of HMG-CoA reductase inhibitors and eicosapentaenoic acids on serum lipid profile and plasma fatty acid concentrations in patients with hyperlipidemia
N Nakamura, T Hamazaki, M Ohta, K Okuda, M Urakaze, S Sawazaki, K Yamazaki, A Satoh, R Temaru, Y Ishikura, M Takata, M Kishida, M Kobayashi
International Journal of Clinical & Laboratory Research 1999
Elementary phenotypes in the neurobiological and genetic study of schizophrenia
LE Adler, R Freedman, RG Ross, A Olincy, MC Waldo
Biological Psychiatry 1999
Randomized crossover study of gemfibrozil versus lovastatin in familial combined hyperlipidemia: Additive effects of combination treatment on lipid regulation
D Zambón, E Ros, C Rodriguez-Villar, JC Laguna, M Vázquez, C Sanllehy, E Casals, JM Sol, G Hernández
Metabolism 1999
ROLE OF THE ENTEROHEPATIC CIRCULATION OF BILE SALTS IN LIPOPROTEIN METABOLISM
AD Cooper
Gastroenterology Clinics of North America 1999
Nutrition
&amp;NA;
Current Opinion in Lipidology 1999
Drug Treatment of Lipid Disorders
AJ Wood, RH Knopp
New England Journal of Medicine 1999
Role of fibrates in the management of hypertriglyceridemia
DJ Rader, SM Haffner
The American Journal of Cardiology 1999
Combined hyperlipidemia as a risk factor for premature atherosclerotic disease
C East
The American Journal of Medicine 1999
Epidemiology of hypertriglyceridemia and cardiovascular disease
MA Austin
The American Journal of Cardiology 1999
Familial Hypercholesterolemia in Utah Kindred with Novel 2412-6 Ins G Mutations in Exon 17 of the LDL Receptor Gene
Y NOBE, M EMI, H KATSUMATA, T NAKAJIMA, T HIRAYAMA, LL WU, SH STEPHENSON, PN HOPKINS, RR WILLIAMS
Japanese Heart Journal 1999
Coronary Flow Reserve in Young Men With Familial Combined Hyperlipidemia
OP Pitkänen, P Nuutila, OT Raitakari, K Porkka, H Iida, I Nuotio, T Rönnemaa, J Viikari, MR Taskinen, C Ehnholm, J Knuuti
Circulation 1999
Linkage of a Candidate Gene Locus to Familial Combined Hyperlipidemia: Lecithin:Cholesterol Acyltransferase on 16q
BE Aouizerat, H Allayee, R M., GM Dallinga-Thie, CD Lanning, TW de Bruin, AJ Lusis, JI Rotter
Arteriosclerosis, thrombosis, and vascular biology 1999
Mutations in the lipoprotein lipase Gene Associated With Ischemic Heart Disease in Men: The Copenhagen City Heart Study
HH Wittrup, A Tybjærg-Hansen, R Steffensen, SS Deeb, JD Brunzell, G Jensen, BG Nordestgaard
Arteriosclerosis, thrombosis, and vascular biology 1999
Pleiotropic Genetic Effects on LDL Size, Plasma Triglyceride, and HDL Cholesterol in Families
KL Edwards, MC Mahaney, AG Motulsky, MA Austin
Arteriosclerosis, thrombosis, and vascular biology 1999
Contemporary Concepts in Cardiology
R Gorlin, G Dangas, PK Toutouzas, MM Konstadoulakis
1999
Genetic control of hepatic apoB-100 secretion in human apoB transgenic mouse strains
E Voyiaziakis, C Ko, SM O'Rourke, LS Huang
Journal of lipid research 1999
Vitamin A is linked to the expression of the AI-CIII-AIV gene cluster in familial combined hyperlipidemia
J Ribalta, J Girona, JC Vallvé, AE Ville, M Heras, L Masana
Journal of lipid research 1999
Association of plasma lipids and apolipoproteins with the insulin response element in the apoC-III promoter region in familial combined hyperlipidemia
M Groenendijk, R, NH Blom, JI Rotter, TW de Bruin, GM Dallinga-Thie
Journal of lipid research 1999
Apolipoprotein B overproduction by the perfused liver of the St. Thomas' mixed hyperlipidemic (SMHL) rabbit
HA Ardern, GM Benson, KE Suckling, MJ Caslake, J Shepherd, CJ Packard
Journal of lipid research 1999
GENETICS OF LIPOPROTEIN DISORDERS
J Davignon, J Genest
Endocrinology & Metabolism Clinics of North America 1998
Defects of lipoprotein metabolism in familial combined hyperlipidaemia
J Graaf, AF Stalenhoef
Current Opinion in Lipidology 1998
Gender-related association between the −93T→G/D9N haplotype of the lipoprotein lipase gene and elevated lipid levels in familial combined hyperlipidemia
MJ Hoffer, SJ Bredie, H Snieder, PW Reymer, PN Demacker, LM Havekes, DI Boomsma, AF Stalenhoef, RR Frants, JJ Kastelein
Atherosclerosis 1998
Glucose intolerance in familial combined hyperlipidaemia
Vakkilainen, Porkka, Nuotio, Pajukanta, Suurinkeroinen, Ylitalo, Viikari, Ehnholm, Taskinen
European Journal of Clinical Investigation 1998
Families with familial combined hyperlipidemia and families enriched for coronary artery disease share genetic determinants for the atherogenic lipoprotein phenotype
H Allayee, BE Aouizerat, RM Cantor, GM Dallinga-Thie, RM Krauss, CD Lanning, JI Rotter, AJ Lusis, TW de Bruin
The American Journal of Human Genetics 1998
A common genetic mechanism determines plasma apolipoprotein B levels and dense LDL subfraction distribution in familial combined hyperlipidemia
SH Juo, SJ Bredie, LA Kiemeney, PN Demacker, AF Stalenhoef
The American Journal of Human Genetics 1998
Candidate-gene studies of the atherogenic lipoprotein phenotype: a sib-pair linkage analysis of DZ women twins
MA Austin, PJ Talmud, LA Luong, L Haddad, IN Day, B Newman, KL Edwards, RM Krauss, SE Humphries
The American Journal of Human Genetics 1998
A study of insulin resistance using the minimal model in nondiabetic familial combined hyperlipidemic patients
JF Ascaso, A Merchante, RI Lorente, JT Real, J Martinez-Valls, R Carmena
Metabolism 1998
Prevention of coronary heart disease in clinical practice: Recommendations of the Second Joint Task Force of European and other Societies on Coronary Prevention1European Society of Cardiology, European Atherosclerosis Society, European Society of Hypertension, International Society of Behavioural Medicine, European Society of General Practice/Family Medicine, European Heart Network.1,2Published simultaneously in the European Heart Journal 1998;19:1434–1503 and the Journal of Hypertension (Summary only) 1998;16(10).2
D Wood, GD Backer, O Faergeman, I Graham, G Mancia, K Pyörälä
Atherosclerosis 1998
Evidence against alterations in Lecithin:cholesterol acyltransferase (LCAT) activity in Familial combined hyperlipidemia
J Ribalta, AE la Ville, JC Vallvé, J Girona, L Masana
Atherosclerosis 1998
Relative contribution of low-density lipoprotein receptor and lipoprotein lipase gene mutations to angiographically assessed coronary artery disease among French Canadians
D Gaudet, MC Vohl, P Julien, G Tremblay, P Perron, C Gagné, J Bergeron, S Moorjani, JP Després
The American Journal of Cardiology 1998
Different regulation of free fatty acid levels and glucose oxidation by the Trp64Arg polymorphism of the β3-adrenergic receptor gene and the promoter variant (A-3826G) of the uncoupling protein 1 gene in familial combined hyperlipidemia
J Pihlajamäki, J Rissanen, R Valve, S Heikkinen, L Karjalainen, M Laakso
Metabolism 1998
Linkage of familial combined hyperlipidaemia to chromosome 1q21–q23
P Pajukanta, I Nuotio, JD Terwilliger, KV Porkka, K Ylitalo, J Pihlajamäki, AJ Suomalainen, AC Syvänen, T Lehtimäki, JS Viikari, M Laakso, MR Taskinen, C Ehnholm, L Peltonen
Nature Genetics 1998
Mapping a gene for combined hyperlipidaemia in a mutant mouse strain
LW Castellani, A Weinreb, J Bodnar, AM Goto, M Doolittle, M Mehrabian, P Demant, AJ Lusis
Nature Genetics 1998
Serum Lipid Physiology and the Influence of Glaucoma Medications
WC Stewart, J Osterman
Survey of Ophthalmology 1998
Advances in Protein Chemistry
CM Silva, J Isgaard, MO Thorner
Advances in Protein Chemistry 1998
Use of Niacin, Statins, and Resins in Patients With Combined Hyperlipidemia
BG PhD, AZ MD, DP BS, AR MS, VM MD, JW BS, JJ PhD, JD MD
The American Journal of Cardiology 1998
Markedly high prevalence of coronary risk factors in apparently healthy african-american and white siblings of persons with premature coronary heart disease
DM Becker, RM Yook, TF Moy, RS Blumenthal, LC Becker
The American Journal of Cardiology 1998
Role of 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase Inhibitors (“Statins”) in Familial Combined Hyperlipidemia
GS MD, CA MD, NE MD
The American Journal of Cardiology 1998
Haplotypes of the ApoA-I/C-III/A-IV gene cluster and familial combined hyperlipidemia
E Tahvanainen, P Pajukanta, K Porkka, S Nieminen, L Ikävalko, I Nuotio, MR Taskinen, L Peltonen, C Ehnholm
Arteriosclerosis, thrombosis, and vascular biology 1998
Overexpression and accumulation of apolipoprotein E as a cause of hypertriglyceridemia
Y Huang, XQ Liu, SC Rall, JM Taylor, A Eckardstein, G Assmann, RW Mahley
The Journal of biological chemistry 1998
Impaired Insulin-Stimulated Glucose Oxidation and Free Fatty Acid Suppression in Patients with Familial Combined Hyperlipidemia: A Precursor Defect for Dyslipidemia?
L Karjalainen, J Pihlajamäki, P Karhapää, M Laakso
Arteriosclerosis, thrombosis, and vascular biology 1998
The Adipocyte, Fatty Acid Trapping, and Atherogenesis
AD Sniderman, K Cianflone, P Arner, LK Summers, KN Frayn
Arteriosclerosis, thrombosis, and vascular biology 1998
Evidence Against Linkage of Familial Combined Hyperlipidemia to the Apolipoprotein AI-CIII-AIV Gene Complex
EM Wijsman, JD Brunzell, GP Jarvik, MA Austin, AG Motulsky, SS Deeb
Arteriosclerosis, thrombosis, and vascular biology 1998
Klinische Angiologie
H Rieger, W Schoop
1998
Herz-Kreislauf-Erkrankungen
D Ganten, K Ruckpaul
1998
Complex genetic contribution of the Apo AI-CIII-AIV gene cluster to familial combined hyperlipidemia. Identification of different susceptibility haplotypes
GM Dallinga-Thie, ML Trip, JI Rotter, RM Cantor, X Bu, AJ Lusis, TW de Bruin
Journal of Clinical Investigation 1997
Lipoprotein lipase gene variants and risk of coronary disease: a quantitative analysis of population-based studies
JE Hokanson
International Journal of Clinical & Laboratory Research 1997
The Relationship of Conjoint Traits of Dyslipidemias between Young Offspring and Their Parents in a Community-Based Sample
W Chen, SR Srinivasan, W Bao, WA Wattigney, GS Berenson
Preventive Medicine 1997
Atherosclerosis
EM MD, ST MD, EA MD, AW MD, ED MD
The Annals of Thoracic Surgery 1997
Genetics of type III hyperlipoproteinemia
G Feussner, S Piesch, J Dobmeyer, C Fischer
Genetic Epidemiology 1997
The acylation stimulating protein pathway: Clinical implications
K Cianflone
Clinical Biochemistry 1997
Gene therapy for atherosclerosis
DJ Rader
International Journal of Clinical & Laboratory Research 1997
Phenotype expression in familial combined hyperlipidemia
KV Porkka, I Nuotio, P Pajukanta, C Ehnholm, L Suurinkeroinen, M Syvänne, T Lehtimäki, AT Lahdenkari, S Lahdenperä, K Ylitalo, M Antikainen, M Perola, OT Raitakari, P Kovanen, JS Viikari, L Peltonen, MR Taskinen
Atherosclerosis 1997
Ziele und praktische Durchführung der Lipidtherapie bei koronarer Herzkrankheit
FU Beil, E Windler
Herz 1997
Comparison of Pravastatin With Crystalline Nicotinic Acid Monotherapy in Treatment of Combined Hyperlipidemia
JM MD, IS MD, GL PhD, SM PhD
The American Journal of Cardiology 1997
Elevated Lp(a) is the most frequent familial lipoprotein disorder leading to premature myocardial infarction in a country with low cholesterol levels
S Pay, N Özcan, SL Tokgözoğlu
International Journal of Cardiology 1997
Serum complement and familial combined hyperlipidemia
K Ylitalo, KV Porkka, S Meri, I Nuotio, L Suurinkeroinen, J Vakkilainen, P Pajukanta, JS Viikari, L Peltonen, C Ehnholm, MR Taskinen
Atherosclerosis 1997
Long-term Treatment With Pravastatin Alone and in Combination With Gemfibrozil in Familial Type IIB Hyperlipoproteinemia or Combined Hyperlipidemia
C Napoli, S Lepore, P Chiariello, M Condorelli, M Chiariello
Journal of cardiovascular pharmacology and therapeutics 1997
Frequencies of a C-T Mutation in Lipoprotein Lipase and a G-A Mutation in Alipoprotein-A1 in Saudi Arabia
J Buraiki, AI Butt, SS Hussain
Annals of Saudi medicine 1997
Detection and characterization of a novel splice mutation in the LDL receptor intron 12 resulting in two different mutant mRNA variants
H Nissen, AB Hansen, P Guldberg, NE Petersen, TS Hansen, M Hørder
Atherosclerosis 1997
A comparative study of the efficacy of simvastatin and gemfibrozil in combined hyperlipoproteinemia: prediction of response by baseline lipids, apo E genotype, lipoprotein(a) and insulin
P Nestel, L Simons, P Barter, P Clifton, D Colquhoun, I Hamilton-Craig, K Sikaris, D Sullivan
Atherosclerosis 1997
The Redox Status of Coenzyme Q10 in Total LDL as an Indicator of In Vivo Oxidative Modification: Studies on Subjects With Familial Combined Hyperlipidemia
YB de Rijke, SJ Bredie, PN Demacker, JM Vogelaar, HL Hak-Lemmers, AF Stalenhoef
Arteriosclerosis, thrombosis, and vascular biology 1997
Defects of Insulin Action on Fatty Acid and Carbohydrate Metabolism in Familial Combined Hyperlipidemia
TJ Aitman, IF Godsland, B Farren, D Crook, HJ Wong, J Scott
Arteriosclerosis, thrombosis, and vascular biology 1997
Segregation Analysis of Plasma Apolipoprotein B Levels in Familial Combined Hyperlipidemia
SJ Bredie, J van Drongelen, LA Kiemeney, PN Demacker, TH Beaty, AF Stalenhoef
Arteriosclerosis, thrombosis, and vascular biology 1997
No Evidence of Linkage Between Familial Combined Hyperlipidemia and Genes Encoding Lipolytic Enzymes in Finnish Families
P Pajukanta, KV Porkka, M Antikainen, MR Taskinen, M Perola, S Murtomäki-Repo, S Ehnholm, I Nuotio, L Suurinkeroinen, AT Lahdenkari, AC Syvänen, JS Viikari, C Ehnholm, L Peltonen
Arteriosclerosis, thrombosis, and vascular biology 1997
Codon 54 Polymorphism of the Human Intestinal Fatty Acid Binding Protein 2 Gene Is Associated With Dyslipidemias But Not With Insulin Resistance in Patients With Familial Combined Hyperlipidemia
J Pihlajamäki, J Rissanen, S Heikkinen, L Karjalainen, M Laakso
Arteriosclerosis, thrombosis, and vascular biology 1997
Etiologic Heterogeneity of Hyperapobetalipoproteinemia (HyperapoB): Results From Segregation Analysis in Families With Premature Coronary Artery Disease
SH Juo, TH Beaty, PO Kwiterovich
Arteriosclerosis, thrombosis, and vascular biology 1997
Heritability Analysis of Lipids and Three Gene Loci in Twins Link the Macrophage Scavenger Receptor to HDL Cholesterol Concentrations
H Knoblauch, A Busjahn, S Münter, Z Nagy, HD Faulhaber, H Schuster, FC Luft
Arteriosclerosis, thrombosis, and vascular biology 1997
Nonobese Patients With Familial Combined Hyperlipidemia Are Insulin Resistant Compared With Their Nonaffected Relatives
SJ Bredie, CJ Tack, P Smits, AF Stalenhoef
Arteriosclerosis, thrombosis, and vascular biology 1997
A variation in the apolipoprotein C-III gene is associated with an increased number of circulating VLDL and IDL particles in familial combined hyperlipidemia
J Ribalta, AE Ville, JC Vallvé, S Humphries, PR Turner, L Masana
Journal of lipid research 1997
Low plasma vitamin A concentrations in familial combined hyperlipidemia
J Ribalta, AE LaVille, J Girona, JC Vallvé, L Masana
Clinical chemistry 1997
Hyperlipidemias
GG Russo
Clinics in Dermatology 1996
High density lipoproteins and coronary heart disease
PJ Barter, KA Rye
Atherosclerosis 1996
The influence of age and relative weight on the presentation of familial combined hyperlipidemia in childhood
R Shamir, AM Tershakovec, PR Gallagher, CA Liacouras, LL Hayman, JA Cortner
Atherosclerosis 1996
Abnormal regulation of the LDL-R and HMG CoA reductase genes in subjects with familial hypercholesterolemia with the “French Canadian Mutation”
L Yu, S Qiu, J Genest
Atherosclerosis 1996
Lipoprotein lipase gene mutations D9N and N291S in four pedigrees with familial combined hyperlipidaemia
TW de Bruin, F Mailly, HH van Barlingen, R Fisher, MC Cabezas, P Talmud, GM Dallinga-Thie, SE Humphries
European Journal of Clinical Investigation 1996
In vitro lipolysis of human VLDL: Effect of different VLDL compositions in normolipidemia, familial combined hyperlipidemia and familial hypertriglyceridemia
HH van Barlingen, LA Kock, FH de Man, DW Erkelens, TW de Bruin
Atherosclerosis 1996
The lipoprotein lipase (Asn291 → Ser) mutation is associated with elevated lipid levels in families with familial combined hyperlipidaemia
MJ Hoffer, SJ Bredie, DI Boomsma, PW Reymer, JJ Kastelein, P Knijff, PN Demacker, AF Stalenhoef, LM Havekes, RR Frants
Atherosclerosis 1996
Two novel apolipoprotein A-IV variants in individuals with familial combined hyperlipidemia and diminished levels of lipoprotein lipase activity
SS Deeb, DN Nevin, L Iwasaki, JD Brunzell
Human Mutation 1996
Inherited susceptibility determines the distribution of dense low-density lipoprotein subfraction profiles in familial combined hyperlipidemia
SJ Bredie, LA Kiemeney, AF de Haan, PN Demacker, AF Stalenhoef
The American Journal of Human Genetics 1996
Recent trends in the consumption of lipid-lowering drugs in Finland
J Martikainen, T Klaukka, A Reunanen, S Peura, H Wahlroos
Journal of Clinical Epidemiology 1996
Apolipoprotein E polymorphism influences lipid phenotypic expression, but not the low density lipoprotein subfraction distribution in familial combined hyperlipidemia
SJ Bredie, JM Vogelaar, PN Demacker, AF Stalenhoef
Atherosclerosis 1996
Oligonucleotide ligation assay (OLA) for the diagnosis of familial hypercholesterolemia
H Baron, S Fung, A Aydin, S Bähring, FC Luft, H Schuster
Nature Biotechnology 1996
TREATMENT OF DYSLIPIDEMIAS
PH MD
Endocrine Practice 1996
Plasma Concentration of Apolipoprotein E in Intermediate-Sized Remnant-Like Lipoproteins in Normolipidemic and Hyperlipidemic Subjects
JS Cohn, M Tremblay, M Amiot, D Bouthillier, M Roy, J Genest, J Davignon
Arteriosclerosis, thrombosis, and vascular biology 1996
Fenofibrate Reduces Plasma Cholesteryl Ester Transfer From HDL to VLDL and Normalizes the Atherogenic, Dense LDL Profile in Combined Hyperlipidemia
M Guérin, E Bruckert, PJ Dolphin, G Turpin, MJ Chapman
Arteriosclerosis, thrombosis, and vascular biology 1996
Higher Triglycerides, Lower High-Density Lipoprotein Cholesterol, and Higher Systolic Blood Pressure in Lipoprotein Lipase–Deficient Heterozygotes: A Preliminary Report
DL Sprecher, BV Harris, EA Stein, PS Bellet, LM Keilson, LA Simbartl
Circulation 1996
Herzkrankheiten
H Roskamm, H Reindell
1996
Drugs Affecting Lipid Metabolism
AM Gotto, R Paoletti, LC Smith, AL Catapano, AS Jackson
1996
Analysis of Apolipoproteins
MF Laker, K Evans
Annals of Clinical Biochemistry 1996
Interaction of the lipoprotein lipase asparagine 291–>serine mutation with body mass index determines elevated plasma triacylglycerol concentrations: a study in hyperlipidemic subjects, myocardial infarction survivors, and healthy adults
RM Fisher, F Mailly, RE Peacock, A Hamsten, M Seed, JS Yudkin, U Beisiegel, G Feussner, G Miller, SE Humphries
Journal of lipid research 1996
Lack of association of the apolipoprotein A-I-C-III-A-IV gene XmnI and SstI polymorphisms and of the lipoprotein lipase gene mutations in familial combined hyperlipoproteinemia in French Canadian subjects
M Marcil, B Boucher, E Gagné, J Davignon, M Hayden, J Genest
Journal of lipid research 1996
Regulatory mutations in the human lipoprotein lipase gene in patients with familial combined hyperlipidemia and coronary artery disease
WS Yang, DN Nevin, L Iwasaki, R Peng, BG Brown, JD Brunzell, SS Deeb
Journal of lipid research 1996
Accumulation of large very low density lipoprotein in plasma during intravenous infusion of a chylomicron-like triglyceride emulsion reflects competition for a common lipolytic pathway
J Bjorkegren, CJ Packard, A Hamsten, D Bedford, M Caslake, L Foster, J Shepherd, P Stewart, F Karpe
Journal of lipid research 1996
Monomethylethanolamine reduces plasma triacylglycerols and apolipoprotein B and increases apolipoprotein A-I rats without induction of fatty liver
AE Rusiñol, PS Lysak, GT Sigurdson, JE Vance
Journal of lipid research 1996
Apolipoprotein A-I/C-III/A-IV gene cluster in familial combined hyperlipidemia: effects on LDL-cholesterol and apolipoproteins B and C-III
GM Dallinga-Thie, XD Bu, M van Linde-Sibenius Trip, JI Rotter, AJ Lusis, TW de Bruin
Journal of lipid research 1996
Impaired activation of adipocyte lipolysis in familial combined hyperlipidemia
S Reynisdottir, M Eriksson, B Angelin, P Arner
Journal of Clinical Investigation 1995
Lipids and atherosclerosis
MJ Halpern
Molecular Aspects of Medicine 1995
A mutation in the promoter of the lipoprotein lipase (LPL) gene in a patient with familial combined hyperlipidemia and low LPL activity
WS Yang, DN Nevin, R Peng, JD Brunzell, SS Deeb
Proceedings of the National Academy of Sciences 1995
FH Tulsa-1 and -2: Two unique alleles for familial hypercholesterolemia presenting in an affected two-year-old African-American male
PR Blackett, DH Altmiller, D Jelley, DP Wilson
American Journal of Medical Genetics 1995
Fasting hyperinsulinism, insulin resistance syndrome, and coronary artery disease in men and women
B Solymoss, M Marcil, M Chaour, B Gilfix, A Poitras, L Campeau
The American Journal of Cardiology 1995
Comparison of gemfibrozil versus simvastatin in familial combined hyperlipidemia and effects on apolipoprotein-B-containing lipoproteins, low-density lipoprotein subfraction profile, and low-density lipoprotein oxidizability
SJ Bredie, TW de Bruin, PN Demacker, JJ Kastelein, AF Stalenhoef
The American Journal of Cardiology 1995
Effect of nibbling versus gorging on cardiovascular risk factors: Serum uric acid and blood lipids
DJ Jenkins, A Khan, AL Jenkins, R Illingworth, AS Pappu, TM Wolever, V Vuksan, G Buckley, AV Rao, SC Cunnane, F Brighenti, M Hawkins, M Abdolell, P Corey, R Patten, RG Josse
Metabolism 1995
Alterations of serum lipid levels and their biological relevances during and after pregnancy
C An-Na, Y Man-Li, H Jeng-Hsiu, C Pesus, S Shin-Kuo, N Heung-Tat
Life Sciences 1995
Management of Primary Hyperlipidemia
AJ Wood, RJ Havel, E Rapaport
New England Journal of Medicine 1995
The genetic determinants of plasma cholesterol and response to diet
SE Humphries, RE Peacock, PJ Talmud
Baillière's Clinical Endocrinology and Metabolism 1995
Clustering of cardiovascular risk factors: Targeting high-risk individuals
J Genest, JS Cohn
The American Journal of Cardiology 1995
Signal sorting by G-protein-linked receptors
G Milligan
Advances in pharmacology (San Diego, Calif.) 1995
Decreases in plasma lipid content and thrombotic activity by ethyl icosapentate purified from fish oils
K Hayashi, H Ohtani, H Kurushima, SI Nomura, K Koide, T Kunita, K Tanaka, Y Yasunobu, M Kambe, G Kajiyama
Current Therapeutic Research 1995
Long-term treatment with simvastatin in patients with familial combined hyperlipidemia
C Napoli, S Lepore, M Condorelli, M Chiariello
Current Therapeutic Research 1995
Antioxidants and Cardiovascular Disease
KR Bruckdorfer
1995
Lipid Profile in the First-Degree Relatives of Patients with Precocious Coronary Heart Disease in Rohtak Area (Northern India)
S Ahlawat, S Gupta, SB Siwach, S Mohan
Angiology 1995
Plasma HDL Cholesterol, Triglycerides, and Adiposity: A Quantitative Genetic Test of the Conjoint Trait Hypothesis in the San Antonio Family Heart Study
MC Mahaney, J Blangero, AG Comuzzie, JL VandeBerg, MP Stern, JW MacCluer
Circulation 1995
Elevated Concentrations of Plasma Lipids and Apolipoproteins B, C-III, and E Are Associated With the Progression of Coronary Artery Disease in Familial Hypercholesterolemic Swine
J Hasler-Rapacz, MF Prescott, JV Linden-Reed, JM Rapacz, Z Hu, J Rapacz
Arteriosclerosis, thrombosis, and vascular biology 1995
Ten LDL Receptor Mutants Explain One Third of Familial Hypercholesterolemia in a German Sample
H Schuster, C Keller, G Wolfram, N Zöllner
Arteriosclerosis, thrombosis, and vascular biology 1995
Multiple Risk Factors in Cardiovascular Disease
AM Gotto, C Lenfant, AL Catapano, R Paoletti
1995
Effects of Different Phenotypes of Hyperlipoproteinemia and of Treatment With Fibric Acid Derivatives on the Rates of Cholesterol 7α-Hydroxylation in Humans
M Bertolotti, M Concari, P Loria, N Abate, A Pinetti, ME Guicciardi, N Carulli
Arteriosclerosis, thrombosis, and vascular biology 1995
LDL Physical and Chemical Properties in Familial Combined Hyperlipidemia
JE Hokanson, RM Krauss, JJ Albers, MA Austin, JD Brunzell
Arteriosclerosis, thrombosis, and vascular biology 1995
A Common Variant in the Gene for Lipoprotein Lipase (Asp9→Asn): Functional Implications and Prevalence in Normal and Hyperlipidemic Subjects
F Mailly, Y Tugrul, PW Reymer, T Bruin, M Seed, BF Groenemeyer, A Asplund-Carlson, D Vallance, AF Winder, GJ Miller, JJ Kastelein, A Hamsten, G Olivecrona, SE Humphries, PJ Talmud
Arteriosclerosis, thrombosis, and vascular biology 1995
Cardiovascular Disease 2
LL Gallo
1995
Prevalence of alleles encoding defective lipoprotein lipase in hypertriglyceridemic patients of French Canadian descent
A Minnich, A Kessling, M Roy, C Giry, G DeLangavant, J Lavigne, S Lussier-Cacan, J Davignon
Journal of lipid research 1995
Triglyceride-rich lipoproteins isolated by selected-affinity anti-apolipoprotein B immunosorption from human atherosclerotic plaque
BS Horowitz, IJ Goldberg, J Merab, TM Vanni, R Ramakrishnan, HN Ginsberg
Journal of Clinical Investigation 1994
Familial lipoprotein disorders and premature coronary artery disease
EJ Schaefer, JJ Genest, JM Ordovas, DN Salem, PW Wilson
Atherosclerosis 1994
ACAT inhibitors as antiatherosclerotic agents: Compounds and mechanisms
K Matsuda
Medicinal Research Reviews 1994
Dyslipoproteinemia and other risk factors for atherosclerosis in children and adolescents
PO Kwiterovich
Atherosclerosis 1994
Association between genetic variation at the APO AI-CIII-AIV gene cluster and familial combined hyperlipidaemia
CF Xu, P Talmud, H Schuster, R Houlston, G Miller, S Humphries
Clinical Genetics 1994
Small, dense low-density lipoprotein as a risk factor for coronary heart disease
MA Austin
International Journal of Clinical & Laboratory Research 1994
Triglyceride-rich lipoproteins isolated by selected-affinity anti-apolipoprotein B immunosorption from human atherosclerotic plaque
BS Horowitz, IJ Goldberg, J Merab, TM Vanni, R Ramakrishnan, HN Ginsberg
Journal of Clinical Investigation 1994
Triglyceride-rich lipoproteins isolated by selected-affinity anti-apolipoprotein B immunosorption from human atherosclerotic plaque
BS Horowitz, IJ Goldberg, J Merab, TM Vanni, R Ramakrishnan, HN Ginsberg
Journal of Clinical Investigation 1994
Familial combined hyperlipidemia in children: Clinical expression, metabolic defects, and management
JA Cortner, PM Coates, CA Liacouras, GP Jarvik
Current Problems in Pediatrics 1994
Combined Treatment with Pravastatin and Gemfibrozil in Patients with Refractory Familial Combined Hyperlipidaemia: A Clinical Study
VG Athyros, AA Papageorgiou, HJ Hagikonstantinou, GV Papadopoulos, CX Zamboulis, AG Kontopoulos
Drug Investigation 1994
Dyslipidemias and the secondary prevention of coronary heart disease
RS Rosenson, WA Frauenheim, CC Tangney
Disease-a-Month 1994
Epidemiology of triglycerides, small dense low-density lipoprotein, and lipoprotein(a) as risk factors for coronary heart disease
MA Austin, JE Hokanson
Medical Clinics of North America 1994
Lipoprotein lipase activity in patients with combined hyperlipidaemia
M Seed, F Mailly, D Vallance, E Doherty, A Winder, P Talmud, SE Humphries
Journal of Molecular Medicine 1994
Complex segregation analysis provides evidence for a major gene acting on serum triglyceride levels in 55 British families with familial combined hyperlipidemia
P Cullen, B Farren, J Scott, M Farrall
Arteriosclerosis Thrombosis and Vascular Biology 1994
Pravastatin effectively lowers LDL cholesterol in familial combined hyperlipidemia without changing LDL subclass pattern
G Franceschini, M Cassinotti, G Vecchio, G Gianfranceschi, F Pazzucconi, T Murakami, M Sirtori, AL D'Acquarica, CR Sirtori
Arteriosclerosis Thrombosis and Vascular Biology 1994
Genetic predictors of FCHL in four large pedigrees. Influence of ApoB level major locus predicted genotype and LDL subclass phenotype
GP Jarvik, JD Brunzell, MA Austin, RM Krauss, AG Motulsky, E Wijsman
Arteriosclerosis Thrombosis and Vascular Biology 1994
Associations of allelic differences at the A-I/C-III/A-IV gene cluster with carotid artery intima-media thickness and plasma lipid transport in hypercholesterolemic-hypertriglyceridemic humans
W Patsch, AR Sharrett, IY Chen, YC Lin-Lee, SA Brown, AM Gotto, E Boerwinkle
Arteriosclerosis Thrombosis and Vascular Biology 1994
Conjoint high triglycerides and low HDL cholesterol across generations. Analysis of proband hypertriglyceridemia and lipid/lipoprotein disorders in first-degree family members
DL Sprecher, MJ Hein, PM Laskarzewski
Circulation 1994
DNA variants at the LPL gene locus associate with angiographically defined severity of atherosclerosis and serum lipoprotein levels in a Welsh population
RK Mattu, EW Needham, R Morgan, A Rees, AK Hackshaw, J Stocks, PC Elwood, DJ Galton
Arteriosclerosis Thrombosis and Vascular Biology 1994
Response to HMG CoA reductase inhibitors in heterozygous familial hypercholesterolemia due to the 10-kb deletion ("French Canadian mutation") of the LDL receptor gene
L Karayan, S Qiu, C Betard, R Dufour, G Roederer, A Minnich, J Davignon, J Genest
Arteriosclerosis Thrombosis and Vascular Biology 1994
Familial and diet-induced hypercholesterolemia in swine. Lipid, ApoB, and ApoA-I concentrations and distributions in plasma and lipoprotein subfractions
JO Hasler-Rapacz, TC Nichols, TR Griggs, DA Bellinger, J Rapacz
Arteriosclerosis Thrombosis and Vascular Biology 1994
Genetic factors in coronary heart disease
U Goldbourt, U de Faire, K Berg
1994
Principles and Treatment of Lipoprotein Disorders
G Schettler, AJ Habenicht
1994
Lipoprotein(a) : new insights into an atherogenic lipoprotein
W Bartens, C Wanner
The Clinical Investigator 1994
Variability of lipid phenotypes in hyperuricaemic-hyperlipidemic patients
E Collantes, F J Tinahones, A Cisnal, J Añon, P Sanchez-Guijo
Clinical Rheumatology 1994
Pravastatin treatment in combined hyperlipidaemia: Effect on plasma lipoprotein levels and size
S Zambon, A Cortella, G Sartore, G Baldo-Enzi, E Manzato, G Crepaldi
European Journal of Clinical Pharmacology 1994
Impaired fatty acid metabolism in familial combined hyperlipidemia. A mechanism associating hepatic apolipoprotein B overproduction and insulin resistance
MC Cabezas, TW de Bruin, HW de Valk, CC Shoulders, H Jansen, DW Erkelens
Journal of Clinical Investigation 1993
Mutations in exon 3 of the lipoprotein lipase gene segregating in a family with hypertriglyceridemia, pancreatitis, and non-insulin-dependent diabetes
DE Wilson, A Hata, LK Kwong, A Lingam, J Shuhua, DN Ridinger, C Yeager, KC Kaltenborn, PH Iverius, JM Lalouel
Journal of Clinical Investigation 1993
Accumulation of "small dense" low density lipoproteins (LDL) in a homozygous patients with familial defective apolipoprotein B-100 results from heterogenous interaction of LDL subfractions with the LDL receptor
W März, MW Baumstark, H Scharnagl, V Ruzicka, S Buxbaum, J Herwig, T Pohl, A Russ, L Schaaf, A Berg
Journal of Clinical Investigation 1993
Ciprofibrate therapy normalises the atherogenic low-density lipoprotein subspecies profile in combined hyperlipidemia
E Bruckert, S Dejager, MJ Chapman
Atherosclerosis 1993
Genetic markers in the apo AI-CIII-AIV gene cluster for combined hyperlipidemia, hypertriglyceridemia, and predisposition to atherosclerosis
A Tybjærg-Hansen, BG Nordestgaard, LU Gerdes, O Færgeman, SE Humphries
Atherosclerosis 1993
Haplotype analysis at the low density lipoprotein receptor locus in normal and familial hypercholesterolemia Norwegian subjects
OK Rødningen, TP Leren, O Røsby, S Tonstad, L Ose, K Berg
Clinical Genetics 1993
Genotype at a major locus with large effects on apolipoprotein B levels predicts familial combined hyperlipidemia
GP Jarvik, TH Beaty, PR Gallagher, PM Coates, JA Cortner
Genetic Epidemiology 1993
The HGAR1 familial hypercholesterolemia pedigree
JE Bailey-Wilson, RC Elston
Genetic Epidemiology 1993
Simvastatin improves chylomicron remnant removal in familial combined hyperlipidemia without changing chylomicron conversion
MC Cabezas, TW de Bruin, LA Kock, W Kortlandt, MV Trip, H Jansen, DW Erkelens
Metabolism 1993
Tulp syndrome
DW Erkelens, TW Bruin, MC Cabezas
The Lancet 1993
Genetic and Environmental Influences on Serum Lipid Levels in Twins
DA Heller, U Faire, NL Pedersen, G Dahlen, GE McClearn
New England Journal of Medicine 1993
Effect on Blood Lipids of Very High Intakes of Fiber in Diets Low in Saturated Fat and Cholesterol
D Jenkins, T Wolever, AV Rao, RA Hegele, SJ Mitchell, T Ransom, DL Boctor, PJ Spadafora, AL Jenkins, C Mehling, LK Relle, PW Connelly, JA Story, EJ Furumoto, P Corey, P Wursch
New England Journal of Medicine 1993
Selection bias in the study of spouse similarity for psychiatric morbidity in clinical samples
GG du Fort, JF Boivin, V Kovess
Comprehensive Psychiatry 1993
Prevalence of hyperapobetalipoproteinemia and other lipoprotein phenotypes in men (aged ≤50 years) and women (≤60 years) with coronary artery disease
PO Kwiterovich, J Coresh, PS Bachorik
The American Journal of Cardiology 1993
Use of cholestyramine in the treatment of children with familial combined hyperlipidemia
CA Liacouras, PM Coates, PR Gallagher, JA Cortner
The Journal of Pediatrics 1993
Identification and treatment of heterozygous familial hypercholesterolemia in children and adolescents
PO Kwiterovich
The American Journal of Cardiology 1993
Molecular Epidemiology
FP Perera, R Santella
Molecular Epidemiology 1993
Metabolic abnormalities in hyperlipidemias
G Marotta, P Pauciullo, M Mancini
Nutrition Research 1993
Tolerability and efficacy of combination therapy with simvastatin plus gemfibrozil in type IIb refractory familial combined hyperlipidemia
PG Col, M Fonda, M Fisicaro, M Tonizzo, M Valenti, L Cattin
Current Therapeutic Research 1993
Effect of pravastatin and omega-3 fatty acids on plasma lipids and lipoproteins in patients with combined hyperlipidemia
C Contacos, PJ Barter, DR Sullivan
Arteriosclerosis Thrombosis and Vascular Biology 1993
Familial hypoalphalipoproteinemia in premature coronary artery disease
J Genest, JM Bard, JC Fruchart, JM Ordovas, EJ Schaefer
Arteriosclerosis Thrombosis and Vascular Biology 1993
Impaired chylomicron remnant clearance in familial combined hyperlipidemia
MC Cabezas, TW de Bruin, H Jansen, LA Kock, W Kortlandt, DW Erkelens
Arteriosclerosis Thrombosis and Vascular Biology 1993
Increased production rates of LDL are common in individuals with low plasma levels of HDL cholesterol, independent of plasma triglyceride concentrations
HN Ginsberg, C Ngai, XJ Wang, R Ramakrishnan
Arteriosclerosis Thrombosis and Vascular Biology 1993
Obese men with type IIB hyperlipidemia are insulin resistant
P Karhapää, E Voutilainen, M Malkki, M Laakso
Arteriosclerosis Thrombosis and Vascular Biology 1993
The effect of lovastatin on very low-density lipoprotein apolipoprotein B production by the liver in familial combined hyperlipidaemia
JA Cortner, MJ Bennett, , PM Coates
Journal of Inherited Metabolic Disease 1993
Stable isotopes show a direct relation between VLDL apoB overproduction and serum triglyceride levels and indicate a metabolically and biochemically coherent basis for familial combined hyperlipidemia
S Venkatesan, P Cullen, P Pacy, D Halliday, J Scott
Arteriosclerosis Thrombosis and Vascular Biology 1993
Dense low density lipoprotein subspecies with diminished oxidative resistance predominate in combined hyperlipidemia
S Dejager, E Bruckert, MJ Chapman
Journal of lipid research 1993
Prevalence of familial hypercholesterolemia among young north Karelian patients with coronary heart disease: a study based on diagnosis by polymerase chain reaction
UM Koivisto, L Hämäläinen, Taskinen, K Kettunen, K Kontula
Journal of lipid research 1993
Effects of fish oil concentrate on lipoproteins and apolipoproteins in familial combined hyperlipidemia
F Tat, C Keller, G Wolfram
The Clinical Investigator 1993
Determinants of fasting plasma triglyceride levels: metabolism of hepatic and intestinal lipoproteins
JA Cortner, NA Le, PM Coates, MJ Bennett, DR Cryer
European Journal of Clinical Investigation 1992
Molecular genetics of the LDL receptor gene in familial hypercholesterolemia
HH Hobbs, MS Brown, JL Goldstein
Human Mutation 1992
Molecular Genetics of Familial Hypercholesterolaemia: Common and Rare Mutations of the Low Density Lipoprotein Receptor Gene
K Kontula, UM Koivisto, P Koivisto, H Turtola
Annals of Medicine 1992
Metabolism of plasma low density lipoproteins in familial combined hyperlipidaemia: effect of acipimox therapy
S Ericsson, M Eriksson, L Berglund, B Angelin
Journal of Internal Medicine 1992
Both inherited susceptibility and environmental exposure determine the low-density lipoprotein-subfraction pattern distribution in healthy Dutch families
J Graaf, DW Swinkels, AF de Haan, PN Demacker, AF Stalenhoef
The American Journal of Human Genetics 1992
Genetic Epidemiology of Low-Density Lipoprotein Subclass Phenotypes
MA Austin
Annals of Medicine 1992
Effects of lovastatin therapy on very-low-density lipoprotein triglyceride metabolism in subjects with combined hyperlipidemia: Evidence for reduced assembly and secretion of triglyceride-rich lipoproteins
Y Arad, R Ramakrishnan, HN Ginsberg
Metabolism 1992
Metabolism of apolipoprotein B in members of a family with accelerated atherosclerosis: Influence of apolipoprotein E-3/E-2 pattern
SM Haffner, RS Kushwaha, WR Hazzard
Metabolism 1992
Bimodality of plasma apolipoprotein B levels in familial combined hyperlipidemia
MA Austin, H Horowitz, E Wijsman, RM Krauss, J Brunzell
Atherosclerosis 1992
Prevalence and geographical distribution of major LDL receptor gene rearrangements in Finland
K Aalto-Setälä, UM Koivisto, TA Miettinen, H Gylling, YA Kesäniemi, M Savolainen, K Pyörälä, T Ebeling, I Mononen, H Turtola, J Viikari, K Kontula
Journal of Internal Medicine 1992
Hypertriglyceridemia: Risks and perspectives
AM Gotto
The American Journal of Cardiology 1992
Therapeutic management of triglycerides: An international perspective
TA Pearson
The American Journal of Cardiology 1992
Epidemiology of triglycerides: A view from Framingham
WP Castelli
The American Journal of Cardiology 1992
A clinical overview of dyslipidemias: Treatment strategies
PH Jones
The American Journal of Medicine 1992
Postprandial Lipoprotein Metabolism in Obese Patients with Moderate Hypertriglyceridaemia: Effects of Gemfibrozil
HH Ditschuneit, M Flechtner-Mors, E Hagel, H Ditschuneit
J INT MED RES 1992
The effect of interferon on the metabolism of LDLs
G Schectman, S Kaul, RA Mueller, EC Borden, AH Kissebah
Arteriosclerosis Thrombosis and Vascular Biology 1992
Familial lipoprotein disorders in patients with premature coronary artery disease
JJ Genest, SS Martin-Munley, JR McNamara, JM Ordovas, J Jenner, RH Myers, SR Silberman, PW Wilson, DN Salem, EJ Schaefer
Circulation 1992
Coronary calcification and its relation to extracoronary atherosclerosis in asymptomatic hypercholesterolemic men. The PCV METRA Group
JL Megnien, V Sene, S Jeannin, A Hernigou, MC Plainfosse, I Merli, V Atger, N Moatti, J Levenson, A Simon
Circulation 1992
The management of hyperlipidaemia: are specialist lipid clinics needed?
M Roche, D Grice, H A Neil, D R Matthews
Journal of the Royal College of Physicians of London 1992
Transgenic mice expressing full-length human apolipoprotein B-100. Full-length human apolipoprotein B mRNA is essentially not edited in mouse intestine or liver
W Xiong, E Zsigmond, AM Gotto, LW Reneker, L Chan
The Journal of biological chemistry 1992
Gene-environment interactions in atherosclerosis
RA Hegele
Molecular and Cellular Biochemistry 1992
Familial chylomicronemia (type I hyperlipoproteinemia) due to a single missense mutation in the lipoprotein lipase gene
D Ameis, J Kobayashi, RC Davis, O Ben-Zeev, MJ Malloy, JP Kane, G Lee, H Wong, RJ Havel, MC Schotz
Journal of Clinical Investigation 1991
Familial combined hyperlipidaemia: Use of stable isotopes to demonstrate overproduction of very low-density lipoprotein apolipoprotein B by the liver
JA Cortner, PM Coates, MJ Bennett, DR Cryer, NA Le
Journal of Inherited Metabolic Disease 1991
Plasma Lipid and Lipoprotein Levels in Childhood
PO Kwiterovich
Annals of the New York Academy of Sciences 1991
Gemfibrozil in familial combined hyperlipidaemia: effect of added low-dose cholestyramine on plasma and biliary lipids
B Ödman, S Ericsson, M Lindmark, L Berglund, B Angelin
European Journal of Clinical Investigation 1991
Genetic Forms of Dyslipidemia in Children
AL Drash
Annals of the New York Academy of Sciences 1991
Lack of evidence for linkage between low-density lipoprotein subclass phenotypes and the apolipoprotein B locus in familial combined hyperlipidemia
MA Austin, E Wijsman, S Guo, RM Krauss, JD Brunzell, S Deeb, GP Vogler
Genetic Epidemiology 1991
Low-density lipoprotein subclass phenotypes and familial combined hyperlipidemia
MA Austin
Diabetes / Metabolism Reviews 1991
The cornea and disorders of lipid metabolism
BJ Barchiesi, RH Eckel, PP Ellis
Survey of Ophthalmology 1991
3. Genetic (primary) forms of hypertriglceridemia
G Assmann, HB Brewer
The American Journal of Cardiology 1991
Oxidative Damage & Repair
A Sevanian
Oxidative Damage & Repair 1991
Alternative fat-restricted diets for hypercholesterolemia and combined hyperlipidemia: feasibility, design, subject recruitment, and baseline characteristics of the dietary alternatives study
CE Walden, BS McCann, B Retzlaff, A Dowdy, M Hanson, B Fish, V Fitzpatrick, W Follette, D Parker, G Gey
Journal of the American College of Nutrition 1991
Myocardial infarction at a young age: mechanisms and management
A Hamsten
1991
Plasma triglyceride and coronary heart disease
MA Austin
Arteriosclerosis Thrombosis and Vascular Biology 1991
Effects of n-3 and n-6 fatty acid-enriched diets on plasma lipoproteins and apolipoproteins in heterozygous familial hypercholesterolemia
KE Friday, RA Failor, MT Childs, EL Bierman
Arteriosclerosis Thrombosis and Vascular Biology 1991
Familial combined hyperlipidaemia linked to the apolipoprotein AI–CIII–AIV gene cluster on chromosome 11q23q–q24
AP Wojciechowski, M Farrall, P Cullen, TM Wilson, JD Bayliss, B Farren, BA Griffn, MJ Caslake, CJ Packard, J Shepherd, R Thakker, J Scott
Nature 1991
Effects of three genetic loci in a pedigree with multiple lipoprotein phenotypes
M Emi, RM Hegele, PN Hopkins, LL Wu, R Plaetke, RR Williams, JM Lalouel
Arteriosclerosis Thrombosis and Vascular Biology 1991
DNA Polymorphisms as Disease Markers
DJ Galton, G Assmann
1991
Prevention of coronary heart disease: putting theory into practice
B Lewis, G Rose
Journal of the Royal College of Physicians of London 1991
Clinical Value of Apolipoprotein Measurement
D Bhatnagar, PN Durrington
Annals of Clinical Biochemistry 1991
Phenotypic expression of heterozygous lipoprotein lipase deficiency in the extended pedigree of a proband homozygous for a missense mutation
DE Wilson, M Emi, PH Iverius, A Hata, LL Wu, E Hillas, RR Williams, JM Lalouel
Journal of Clinical Investigation 1990
Biliary lipids in familial combined hyperlipidaemia: effects of acipimox therapy
S Ericsson, M Eriksson, B Angelin
European Journal of Clinical Investigation 1990
Increased degradation of low density lipoproteins by mononuclear leukocytes associated with coronary artery disease
F Shi, PG Hurst, DJ McNamara
Atherosclerosis 1990
Variation at the apolipoprotein (apo) AI-CIII-AIV gene cluster and apo B gene loci is associated with lipoprotein and apolipoprotein levels in Italian children
CF Xu, MN Nanjee, J Savill, PJ Talmud, F Angelico, MD Ben, R Antonini, B Mazzarella, N Miller, SE Humphries
The American Journal of Human Genetics 1990
Genetic evidence from 7 families that the apolipoprotein B gene is not involved in familial combined hyperlipidemia
G Rauh, H Schuster, B Miller, S Schewe, C Keller, G Wolfram, N Zöllner
Atherosclerosis 1990
Wives of coronary high-risk men - are they also at higher risk? The Tromsø Heart Study
SF Knutsen, R Knutsen
Journal of Internal Medicine 1990
Regression of Coronary Artery Disease as a Result of Intensive Lipid-Lowering Therapy in Men with High Levels of Apolipoprotein B
G Brown, JJ Albers, LD Fisher, SM Schaefer, JT Lin, C Kaplan, XQ Zhao, BD Bisson, VF Fitzpatrick, HT Dodge
New England Journal of Medicine 1990
Rising cholesterol levels in children with Familial Hypercholesterolaemia
AM Kessling, M Seed, R Taylor, V Wynn, SE Humphries
Biomedicine & Pharmacotherapy 1990
Aspects génétiques et physiopathologiques des dyslipoprotéinémies athérogènes
G Turpin, E Bruckert
La Revue de Médecine Interne 1990
Use of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors in various forms of dyslipidemia
SM Grundy, GL Vega, A Garg
The American Journal of Cardiology 1990
Prevalence and expression of familial combined hyperlipidemia in childhood
JA Cortner, PM Coates, PR Gallagher
The Journal of Pediatrics 1990
Atherogenic lipoprotein phenotype. A proposed genetic marker for coronary heart disease risk
MA Austin, MC King, KM Vranizan, RM Krauss
Circulation 1990
2 Practical drug therapy for common hyperlipidaemias
MJ Tikkanen
Baillière's Clinical Endocrinology and Metabolism 1990
Lipoprotein (A)
EF Plow, LA Miles
Lipoprotein (A) 1990
Diagnosis and Management of Familial Dyslipoproteinemia in Children and Adolescents
PO Kwiterovich
Pediatric Clinics of North America 1990
Drug Therapy in Dyslipidemia
SM Grundy
Scandinavian Journal of Clinical & Laboratory Investigation 1990
Genetics of Common Diseases of Adulthood
MB Lubin, HJ Lin, CM Vadheim, JI Rotter
Clinics in Perinatology 1990
Inheritance of low density lipoprotein subclass patterns in familial combined hyperlipidemia
MA Austin, JD Brunzell, WL Fitch, RM Krauss
Arteriosclerosis (Dallas, Tex.) 1990
Causes of high blood cholesterol
SM Grundy, GL Vega
Circulation 1990
Current Status of Clinical Cardiology 1990
DG Julian
1990
Advances in Human Genetics
H Harris, K Hirschhorn
1990
Lovastatin therapy reduces low density lipoprotein apoB levels in subjects with combined hyperlipidemia by reducing the production of apoB-containing lipoproteins: implications for the pathophysiology of apoB production
Y Arad, R Ramakrishnan, HN Ginsberg
Journal of lipid research 1990
DNA polymorphisms at the lipoprotein lipase gene: associations in normal and hypertriglyceridaemic subjects
JC Chamberlain, JA Thorn, K Oka, DJ Galton, J Stocks
Atherosclerosis 1989
Regulation of cholesterol synthesis and the potential for its pharmacologic manipulation
RA Davis, M Sinensky, LH Junker
Pharmacology & Therapeutics 1989
Genetic influences on susceptibility to atherosclerosis in the young
PO Kwiterovich
Bulletin of the New York Academy of Medicine 1989
Polymorphic DNA haplotypes at the LDL receptor locus
E Leitersdorf, A Chakravarti, HH Hobbs
The American Journal of Human Genetics 1989
Risk factors in middle age that predict early and late onset of coronary heart disease
RJ Benfante, DM Reed, CJ MacLean, K Yano
Journal of Clinical Epidemiology 1989
Different localization of early arterial lesions in insulin-dependent diabetes mellitus and in familial hypercholesterolemia
P Rubba, G Riccardi, P Pauciullo, O Vaccaro, L Carbone, M Mancini
Metabolism 1989
Comparative Study of Bezafibrate and Probucol in Hyperlipidaemia
JP Moreno, G Gonzàlez
Current Medical Research and Opinion 1989
The Xba1 polymorphism of the apolipoprotein B gene influences the degradation of low density lipoprotein in vitro
J Series, I Cameron, M Caslake, D Gaffney, CJ Packard, J Shepherd
Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism 1989
Effect of low density lipoproteins, high density lipoproteins, and cholesterol on apolipoprotein A-I mRNA in Hep G2 cells
JC Monge, JM Hoeg, SW Law, HB Brewer
FEBS Letters 1989
Nutritional Management of Plasma Lipid Disorders
S Margolis, AS Dobs
Journal of the American College of Nutrition 1989
Nibbling versus Gorging: Metabolic Advantages of Increased Meal Frequency
DJ Jenkins, TM Wolever, V Vuksan, F Brighenti, SC Cunnane, AV Rao, AL Jenkins, G Buckley, R Patten, W Singer, P Corey, RG Josse
New England Journal of Medicine 1989
The Hyperlipoproteinemias
W Patsch, JR Patsch, AM Gotto
Medical Clinics of North America 1989
A Review of Combined Hyperlipidaemia and Its Treatment with Fenofibrate
HR Superko
J INT MED RES 1989
The Status of Hypertriglyceridemia as a Risk Factor for Coronary Heart Disease
AL Avins, RJ Haber, SB Hulley
Clinics in Laboratory Medicine 1989
Detection and characterization of the heterozygote state for lipoprotein lipase deficiency
SP Babirak, PH Iverius, WY Fujimoto, JD Brunzell
Arteriosclerosis (Dallas, Tex.) 1989
Enhanced lipoprotein lipase secretion from human monocyte-derived macrophages caused by hypertriglyceridemic very low density lipoproteins
S Ishibashi, N Mori, T Murase, H Shimano, T Gotohda, M Kawakami, Y Akanuma, F Takaku, N Yamada
Arteriosclerosis (Dallas, Tex.) 1989
Rational therapy of familial hypercholesterolemia
GA Reynolds
Circulation 1989
Apolipoprotein, low density lipoprotein subfraction, and insulin associations with familial combined hyperlipidemia. Study of Utah patients with familial dyslipidemic hypertension
SC Hunt, LL Wu, PN Hopkins, BM Stults, H Kuida, ME Ramirez, JM Lalouel, RR Williams
Arteriosclerosis (Dallas, Tex.) 1989
Homozygous familial hypercholesterolemia among French Canadians in Québec Province
S Moorjani, M Roy, C Gagné, J Davignon, D Brun, M Toussaint, M Lambert, L Campeau, S Blaichman, P Lupien
Arteriosclerosis (Dallas, Tex.) 1989
Apolipoproteins in lipid transport, an impressionist view
DW Erkelens
Postgraduate medical journal 1989
Borderline hypercholesterolaemia: when to introduce drugs
D Bhatnagar, PN Durrington
Postgraduate medical journal 1989
Lipoprotein Subfractions Omega-3 Fatty Acids
HU Klör
1989
Low density lipoprotein subfractions and relationship to other risk factors for coronary artery disease in healthy individuals
DW Swinkels, PN Demacker, JC Hendriks,
Arteriosclerosis (Dallas, Tex.) 1989
Relationships between LDL density and kinetic heterogeneity in subjects with normolipidemia and familial combined hyperlipidemia using density gradient ultracentrifugation
CA Marzetta, DM Foster, JD Brunzell
Journal of lipid research 1989
Genetic analysis of total cholesterol and triglycerides in a pedigree of St. Thomas rabbits
TH Beaty, PO Kwiterovich, A Laville, B Lewis
Journal of lipid research 1989
Clinical consequences of hyperlipidaemia
GR Thompson
Journal of Inherited Metabolic Disease 1988
Serum lipid levels in elementary and junior high school children and their relationship to relative weight
A Yamamoto, H Horibe, S Sawada, M Uyama, Y Matsuzawa, T Yamamura, S Yokoyama, F Kasagi, K Kameda
Preventive Medicine 1988
Risk factors in siblings of people with premature coronary heart disease
DM Becker, LC Becker, TA Pearson, DJ Fintel, DM Levine, PO Kwiterovich
Journal of the American College of Cardiology 1988
Inborn errors of lipid metabolism-dermatological aspects
R Knobler, S Becerano, W Gebhart
Clinical and Experimental Dermatology 1988
Biochemical, clinical, genetic and metabolic studies of hyperapo-β-lipoproteinaemia
PO Kwiterovich
Journal of Inherited Metabolic Disease 1988
Apolipoproteins, Dyslipoproteinaemia and Premature Coronary Heart Disease
A Hamsten
Acta Medica Scandinavica 1988
Effect of the amount of body fat on the age-associated increase in serum cholesterol
JP Després, A Tremblay, C Leblanc, C Bouchard
Preventive Medicine 1988
Inheritance of low-density lipoprotein subclass patterns: results of complex segregation analysis
MA Austin, MC King, KM Vranizan, B Newman, RM Krauss
The American Journal of Human Genetics 1988
The Salmon lecture. Some perspectives on human obesity: its causes
AJ Stunkard
Bulletin of the New York Academy of Medicine 1988
Comparison of gemfibrozil and clofibrate on serum lipids in familial combined hyperlipidemia
SW Rabkin, M Hayden, J Frohlich
Atherosclerosis 1988
Apolipoprotein measurements in clinical biochemistry and their utility vis-a-vis conventional assays
PS Bachorik, PO Kwiterovich
Clinica Chimica Acta 1988
Cases are not incidence and Vice Versa
CR Scriver
Genetic Epidemiology 1988
The effects of ω3 and ω6 fatty acid-enriched diets on plasma lipoproteins and apoproteins in familial combined hyperlipidemia
RA Failor, MT Childs, EL Bierman
Metabolism 1988
Receptors
ML Welton, E Passaro
The American Journal of Surgery 1988
HMG-CoA Reductase Inhibitors for Treatment of Hypercholesterolemia
JA Oates, AJ Wood, SM Grundy
New England Journal of Medicine 1988
Lessons from the Helsinki Heart Study: Fibric acid therapy for dyslipidemia
SM Grundy
Postgraduate Medicine 1988
Plasma cholesterol esterification rate in hyperlipoproteinaemia: Relation to cholesterol elimination
B Angelin, K Einarsson, B Leijd, L Wallentin
Scandinavian Journal of Clinical & Laboratory Investigation 1988
Very low density lipoprotein triglyceride metabolism in relatives of hypertriglyceridemic probands. Evidence for genetic control of triglyceride removal
T Sane, EA Nikkilä
Arteriosclerosis (Dallas, Tex.) 1988
Hyperinsulinemia is characterized by jointly disturbed plasma VLDL, LDL, and HDL levels. A population-based study
M Modan, H Halkin, A Lusky, P Segal, Z Fuchs, A Chetrit
Arteriosclerosis (Dallas, Tex.) 1988
Eicosanoids, Apolipoproteins, Lipoprotein Particles, and Atherosclerosis
CL Malmendier, P Alaupovic
1988
Studies in Inherited Metabolic Disease
RJ Pollitt, RA Harkness, GM Addison
1988
Diagnosis of Familial Hypercholesterolaemia Using DNA Probes for the Low-Density Lipoprotein (LDL) Receptor Gene
AE Armston, SA Iversen, JF Burke
Annals of Clinical Biochemistry 1988
Genetic factors affecting blood lipoproteins: the candidate gene approach
AJ Lusis
Journal of lipid research 1988
Cell type-specific expression of the human apoB gene is controlled by two cis-acting regulatory regions
HK Das, T Leff, JL Breslow
The Journal of biological chemistry 1988
Assay of unesterified cholesterol-5,6-epoxide in human serum by isotope dilution mass spectrometry. Levels in the healthy state and in hyperlipoproteinemia
I Björkhem, O Breuer, B Angelin, SA Wikström
Journal of lipid research 1988
Normal and Pathological Lipoprotein Metabolism:
GR Thompson
Drugs 1988
Introduction
LD Peachey, JP Heath, KR Porter, HP Thompson, KR Porter, F Kallman
Journal of Electron Microscopy Technique 1987
Pharmacological treatment of lipid disorders in diabetes mellitus
MF Lopes-Virella, JA Colwell
Diabetes / Metabolism Reviews 1987
Abstract
A Bardo
Acta Paediatrica 1987
Likelihoods in pedigree analysis under sequential sampling
E Thompson
The American Journal of Human Genetics 1987
Bile acid metabolism in hereditary forms of hypertriglyceridemia: evidence for an increased synthesis rate in monogenic familial hypertriglyceridemia
B Angelin, KS Hershon, JD Brunzell
Proceedings of the National Academy of Sciences 1987
DNA polymorphisms in and around the Apo-A1-CIII genes and genetic hyperlipidemias
MR Hayden, H Kirk, C Clark, J Frohlich, S Rabkin, R McLeod, J Hewitt
The American Journal of Human Genetics 1987
Borderline fasting hypertriglyceridemia: Absence of excess risk of all-cause and cardiovascular disease mortality in healthy men without hypercholesterolemia
E Barrett-Connor, KT Khaw
Preventive Medicine 1987
Genetic analysis of serum lipid levels and blood pressure in a large kindred
ML Marazita, RC Elston, KK Namboodiri, CG Hames, JM Opitz, JF Reynolds
American Journal of Medical Genetics 1987
DISEASE, LIFESTYLE, AND CONSANGUINITY IN 58 AMERICAN GYPSIES
JD Thomas, MM Doucette, DC Thomas, JD Stoeckle
The Lancet 1987
Apolipoprotein E polymorphism and plasma cholesterol response to probucol
AC Nestruck, D Bouthillier, CF Sing, J Davignon
Metabolism 1987
Effects of benfluorex on patients with endogenous hypertriglyceridaemia
R Ranquin
Current Medical Research and Opinion 1987
PLASMINOGEN ACTIVATOR INHIBITOR IN PLASMA: RISK FACTOR FOR RECURRENT MYOCARDIAL INFARCTION
A Hamsten, G Walldius, A Szamosi, M Blombäck, UD Faire, G Dahlén, C Landou, B Wiman
The Lancet 1987
Hyperlipidemia in School Children with Family Histories of Premature Coronary Heart Disease
T Sveger, G Fex, N Borgfors
Acta Paediatrica 1987
8 Dietary therapy of hyperlipidaemia
SM Grundy
Baillière's Clinical Endocrinology and Metabolism 1987
Risk factors for coronary artery disease in families of young men with myocardial infarction
A Hamsten, U Faire
The American Journal of Cardiology 1987
Lipoprotein abnormalities in hypertriglyceridemia: Significance in atherosclerosis
S Eisenberg
American Heart Journal 1987
Potential use of fenofibrate and other fibric acid derivatives in the clinic
WV Brown
The American Journal of Medicine 1987
Severe Hypertriglyceridemia, large lipoproteins and protection against atherosclerosis
BG Nordestgaard, S Stender, K Kjeldsen
Scandinavian Journal of Clinical & Laboratory Investigation 1987
Hyperapobetalipoproteinemia in a kindred with familial combined hyperlipidemia and familial hypercholesterolemia
PO Kwiterovich, S White, T Forte, PS Bachorik, H Smith, A Sniderman
Arteriosclerosis (Dallas, Tex.) 1987
Dietary therapy for different forms of hyperlipoproteinemia
SM Grundy
Circulation 1987
Extracranial carotid arterial disease in patients with familial hypercholesterolemia and coronary artery disease treated with colestipol and nicotinic acid
PT Kuo, JF Toole, JA Schaaf, A Jones, AC Wilson, JB Kostis, AE Moreyra
Stroke; a journal of cerebral circulation 1987
Expanding Horizons in Atherosclerosis Research
G Schlierf, H Mörl
1987
Human Genetics
F Vogel, K Sperling
Human Genetics 1987
Identification of deletions in the human low density lipoprotein receptor gene
B Horsthemke, A Dunning, S Humphries
Journal of medical genetics 1987
Atherogenesis and Aging
SR Bates, EC Gangloff
1987
Lipid-Lowering Drugs: An Overview of Indications and Optimum Therapeutic Use
DR Illingworth
Drugs 1987
Association of a DNA polymorphism in the apolipoprotein C-III gene with diverse hyperlipidaemic phenotypes
H E Henderson, S V Landon, J Michie, G M Berger
Human Genetics 1987
Metabolic basis of hyperapobetalipoproteinemia. Turnover of apolipoprotein B in low density lipoprotein and its precursors and subfractions compared with normal and familial hypercholesterolemia
B Teng, AD Sniderman, AK Soutar, GR Thompson
Journal of Clinical Investigation 1986
Ein Rezeptor-vermittelter Stoffwechselweg für die Cholesterin-Homöostase (Nobel-Vortrag)
MS Brown, JL Goldstein
Angewandte Chemie 1986
GENETIC CONTROL OF LOW-DENSITY-LIPOPROTEIN SUBCLASSES
MA Austin, RM Krauss
The Lancet 1986
Genetic and cultural inheritance of serum lipids, low and high density lipoprotein cholesterol and serum apolipoproteins A-I, A-II and B
A Hamsten, L Iselius, G Dahlén, U Faire
Atherosclerosis 1986
Effect of Gemfibrozil on lipids, apoproteins, and postheparin lipolytic activities in normolipidemic subjects
A Gnasso, B Lehner, W Haberbosch, O Leiss, K Bergmann, J Augustin
Metabolism 1986
Low density lipoprotein metabolism in familial combined hyperlipidemia and familial hypercholesterolemia: Kinetic analysis using an integrated model
A Chait, DM Foster, JJ Albers, RA Failor, JD Brunzell
Metabolism 1986
The Relation of Apolipoproteins A-I and B in Children to Parental Myocardial Infarction
DS Freedman, SR Srinivasan, CL Shear, FA Franklin, LS Webber, GS Berenson
New England Journal of Medicine 1986
Health Effects of Polyunsaturated Fatty Acids in Seafoods
SM Grundy
Health Effects of Polyunsaturated Fatty Acids in Seafoods 1986
Hyperlipoproteinaemia and Xanthomatosis as a Model of Cholesterol Ester Accumulation
BJ Vermeer
The Journal of Dermatology 1986
Identification and Relative Weight of Cardiovascular Risk Factors
PN Hopkins, RR Williams
Cardiology Clinics 1986
Genetic aspects of arteriosclerosis
U Goldbourt, HN Neufeld
Arteriosclerosis (Dallas, Tex.) 1986
Plasma lipoproteins, apolipoproteins, and triglyceride metabolism in familial hypertriglyceridemia
AF Stalenhoef, PN Demacker, JA Lutterman,
Arteriosclerosis (Dallas, Tex.) 1986
Genetic Disorders and the Fetus
A Milunsky
1986
Persistent Renal-Genitourinary Disorders
J Strauss
1986
Hyperlipoproteinaemia in primary gout: hyperlipoproteinaemic phenotype and influence of alcohol intake and obesity in Japan
S Jiao, K Kameda, Y Matsuzawa, S Tarui
Annals of the rheumatic diseases 1986
A receptor-mediated pathway for cholesterol homeostasis
Brown, JL Goldstein
Science 1986
The Genetics of Cardiovascular Disease
ME Pierpont, JH Moller
1986
Receptor-Mediated Uptake in the Liver
H Greten, E Windler, U Beisiegel
1986
Der Stoffwechsel der Plasmalipoproteine und seine Bedeutung für die Pathogenese der Arteriosklerose
G Schettler
1986
Genetische Aspekte von Herz- und Kreislaufkrankheiten
H Moser
Sozial- und Präventivmedizin SPM 1985
The effect of selective breeding on the development of coronary atherosclerosis in WHHL rabbits An animal model for familial hypercholesterolemia
Y Watanabe, T Ito, M Shiomi
Atherosclerosis 1985
A COMMON DNA POLYMORPHISM OF THE LOW-DENSITY LIPOPROTEIN (LDL) RECEPTOR GENE AND ITS USE IN DIAGNOSIS
SE Humphries, B Horsthemke, M Seed, M Holm, V Wynn, AM Kessling, JA Donald, N Jowett, DJ Galton, R Williamson
The Lancet 1985
Lack of a persistent reduction in serum lipid and apoprotein levels in insulin-dependent diabetic patients receiving intensified insulin treatment
RB Goldberg, ML Reeves, DE Seigler, EA Ryan, N Miller, SL Hsia, JS Skyler
Acta Diabetologica Latina 1985
Impaired catabolism of very low-density lipoprotein-triglyceride in a family with primary hypertriglyceridemia
FL Dunn, SM Grundy, DW Bilheimer, RJ Havel, P Raskin
Metabolism 1985
Familial associations of lipids and lipoproteins in a highly consanguineous population: The Limone sul Garda study
V Gualandri, GB Orsini, A Cerrone, G Franceschini, CR Sirtori
Metabolism 1985
Effects of high cholesterol high fat diet on plasma lipoproteins in familial hypercholesterolemia
TG Cole, B Pfleger, O Hitchins, G Schonfeld
Metabolism 1985
Altered HDL subclasses in endogenous hypertriglyceridemia are not affected by weight reduction
B Gonen, W Patsch, I Kuisk, A Goldberg, R Phair, G Schonfeld
Metabolism 1985
Contrasting effects of unmodified and time-release forms of niacin on lipoproteins in hyperlipidemic subjects: Clues to mechanism of action of niacin
RH Knopp, J Ginsberg, JJ Albers, C Hoff, JT Ogilvie, GR Warnick, E Burrows, B Retzlaff, M Poole
Metabolism 1985
Improved reactive hyperemia test after plasma exchange in familial hypercholesterolemia
P Rubba, A Postiglione, N Scarpato, A Iannuzzi, M Mancini
Atherosclerosis 1985
Xanthomas and hyperlipidemias
F Parker
Journal of the American Academy of Dermatology 1985
Familial aggregation and early expression of hyperapobetalipoproteinemia
A Sniderman, B Teng, J Genest, K Cianflone, S Wacholder, P Kwiterovich
The American Journal of Cardiology 1985
Genetic and Metabolic Disease in Pediatrics
L Pinsky, M Kaufman
Genetic and Metabolic Disease in Pediatrics 1985
Pathogenesis and Management of Lipoprotein Disorders
JS Flier, LH Underhill, EJ Schaefer, RI Levy
New England Journal of Medicine 1985
Characterization of plasma lipids and lipoproteins in cholesteryl ester storage disease
DR Kelly, JM Hoeg, SJ Demosky, HB Brewer
Biochemical Medicine 1985
Familial Combined Hyperlipidemia and Otosclerosis—The Occurrence in a Large Kindred
Y Levy, MD Silva, I Eliachar, Z Glick-Avraham, RJ Viskoper, JG Brook
The American Journal of the Medical Sciences 1985
Apo E allele frequency in primary endogenous hypertriglyceridemia (type IV) with and without hyperapobetalipoproteinemia
S Lussier-Cacan, D Bouthillier, J Davignon
Arteriosclerosis (Dallas, Tex.) 1985
Relative contribution of triglyceride-rich lipoprotein particle size and number to plasma triglyceride concentration
M Poapst, M Reardon, G Steiner
Arteriosclerosis (Dallas, Tex.) 1985
Drugs Affecting Lipid Metabolism VIII
D Kritchevsky, WL Holmes, R Paoletti
1985
Identification of a deletion in the low density lipoprotein (LDL) receptor gene in a patient with familial hypercholesterolaemia
B Horsthemke, AM Kessling, M Seed, V Wynn, R Williamson, SE Humphries
Human Genetics 1985
Influence of mevinolin on metabolism of low density lipoproteins in primary moderate hypercholesterolemia
SM Grundy, GL Vega
Journal of lipid research 1985
Low density lipoprotein metabolism in hypertriglyceridemic and normolipidemic patients with coronary heart disease
GL Vega, WF Beltz, SM Grundy
Journal of lipid research 1985
When and How to Treat Hyperlipidemia
PT Kuo
Primary care 1985
Plasma and lipoprotein lipid responses to four hypolipid drugs
WR Hazzard, PW Wahl, C Gagne, D Applebaum-Bowden, GR Warnick, JJ Albers
Lipids 1984
Family history as an independent risk factor for coronary artery disease
S Shea, R Ottman, C Gabrieli, Z Stein, A Nichols
Journal of the American College of Cardiology 1984
The use of polymorphic DNA and protein markers for the third complement component for determining linkage of familial hypercholesterolaemia
SE Humphries, JA Donald, JJ McFadden, S Shull, R Williamson, NI Jowett, DJ Galton, JO Julsrud, K Berg, A Heiberg, S Ball, G Fey, M Seed, V Wynn
Atherosclerosis 1984
Apoproteins: determinants of lipoprotein metabolism and indices of coronary risk
G Thompson
British heart journal 1984
Comparisons of different sampling designs for the determination of genetic transmission mechanisms in quantitative traits
TL Burns, PP Moll, MA Schork
The American Journal of Human Genetics 1984
Hyperlipemia and arteriosclerotic cardiovascular disease in the Polynesian population of Rarotonga
G Egusa, PH Bennett, K Aleck, R Taylor, BV Howard
Atherosclerosis 1984
The collaborative lipid research clinics program family study: Detection of major genes influencing lipid levels by examination of heterogeneity of familial variances
P Green, AR Owen, K Namboodiri, D Hewitt, LR Williams, RC Elston, BM Rifkind, DC Rao
Genetic Epidemiology 1984
The effect of diabetic control on very low-density lipoprotein—Triglyceride metabolism in patients with type II diabetes mellitus and marked hypertriglyceridemia
FL Dunn, P Raskin, DW Bilheimer, SM Grundy
Metabolism 1984
Hyperlipoproteinemia: Metabolic basis and rationale for therapy
SM Grundy
The American Journal of Cardiology 1984
Cardiovascular features of homozygous familial hypercholesterolemia: Analysis of 16 patients
DL Sprecher, EJ Schaefer, KM Kent, RE Gregg, LA Zech, JM Hoeg, B McManus, WC Roberts, HB Brewer
The American Journal of Cardiology 1984
Low-dose colestipol plus probucol for hypercholesterolemia
CA Dujovne, SB Chernoff, P Krehbiel, B Jackson, S DeCoursey, H Taylor
The American Journal of Cardiology 1984
Genetic Factors in Nutrition
NW Solomons
Genetic Factors in Nutrition 1984
Treating Hyperlipidemia to Provide Salutary Effect on Coronary Artery Disease
PT Kuo
Chest 1984
Treatment of common lipoprotein disorders
WV Brown, IJ Goldberg, HN Ginsberg
Progress in Cardiovascular Diseases 1984
Low density lipoprotein metabolism in familial combined hyperlipidemia. Mechanism of the multiple lipoprotein phenotypic expression
AH Kissebah, S Alfarsi, DJ Evans
Arteriosclerosis (Dallas, Tex.) 1984
Physiologic and supraphysiologic increases in lipoprotein lipids and apoproteins in late pregnancy and postpartum. Possible markers for the diagnosis of "prelipemia"
A Montes, CE Walden, RH Knopp, M Cheung, MB Chapman, JJ Albers
Arteriosclerosis (Dallas, Tex.) 1984
Apoproteins B and A-I and coronary artery disease in humans
JD Brunzell, AD Sniderman, JJ Albers, PO Kwiterovich
Arteriosclerosis (Dallas, Tex.) 1984
Studies of hypercholesterolemia in the nonhuman primate. II. Fatty streak conversion to fibrous plaque
A Faggiotto, R Ross
Arteriosclerosis (Dallas, Tex.) 1984
Studies of hypercholesterolemia in the nonhuman primate. I. Changes that lead to fatty streak formation
A Faggiotto, R Ross, L Harker
Arteriosclerosis (Dallas, Tex.) 1984
Premature development of iliac artery stenosis in asymptomatic type II hyperlipoproteinemia
P Rubba, A Postiglione, BD Simone, F Faccenda, G Riccardi, M Mancini
Arteriosclerosis (Dallas, Tex.) 1984
Pathogenesis of hyperlipoproteinemia
SM Grundy
Journal of lipid research 1984
Conference on Blood Lipids in Children: Optimal Levels for Early Prevention of Coronary Artery Disease
RW Wissler, HC McGill
Preventive Medicine 1983
Screening for Health Risks
G Sigurdsson, N Sigfusson, T Thorsteinsson, O Olafsson, D Davidsson, S Samuelsson
Acta Medica Scandinavica 1983
Atherosclerosis and apoproteins B and A-I
PO Kwiterovich, AD Sniderman
Preventive Medicine 1983
Low density lipoprotein degradation by mononuclear cells from normal and dyslipoproteinemic subjects
AM Lees, RS Lees
Proceedings of the National Academy of Sciences 1983
Normocholesterolemic tendon xanthomatosis with overproduction of apolipoprotein B
GL Vega, DR Illingworth, SM Grundy, FT Lindgren, WE Connor
Metabolism 1983
Severe hypertriglyceridemia: Role of familial and acquired disorders
A Chait, JD Brunzell
Metabolism 1983
Phenotypic heterogeneity in the extended pedigree of a proband with lipoprotein lipase deficiency
DE Wilson, CQ Edwards, IF Chan
Metabolism 1983
New Comprehensive Biochemistry
S Yamamoto
New Comprehensive Biochemistry 1983
Genetic and familial factors in essential hypertension and related traits
RM Siervogel
American Journal of Physical Anthropology 1983
Defective Lipoprotein Receptors and Atherosclerosis: Lessons from an Animal Counterpart of Familial Hypercholesterolemia
FH Epstein, JL Goldstein, T Kita, MS Brown
New England Journal of Medicine 1983
Developments in Statistics
S Karlin, EC Cameron, PT Williams
Developments in Statistics 1983
Disorders of lipid transport—Update 1983
G Schonfeld
Progress in Cardiovascular Diseases 1983
Overproduction of low density lipoproteins associated with coronary heart disease
YA Kesaniemi, SM Grundy
Arteriosclerosis (Dallas, Tex.) 1983
Influence of weight reduction on plasma lipoproteins in obese patients
RN Wolf, SM Grundy
Arteriosclerosis (Dallas, Tex.) 1983
Hyperlipidemia in the Pacific Northwest Bell Telephone Company Health Survey. Part 1. Lipoprotein cholesterol and triglyceride concentrations
CE Walden, PW Wahl, RH Knopp, GR Warnick, JT Ogilvie, WR Hazzard, JJ Hoover, JJ Albers
Arteriosclerosis (Dallas, Tex.) 1983
Hyperlipidemia in the Pacific Northwest Bell Telephone Company Health Survey. Part 2. Lipoprotein lipid interrelationships
CE Walden, RH Knopp, PW Wahl, JJ Hoover, JJ Albers, WR Hazzard, JT Ogilvie, GR Warnick
Arteriosclerosis (Dallas, Tex.) 1983
Interaction of two lipid disorders in a large French-Canadian kindred
J Davignon, S Lussier-Cacan, A Gattereau, PP Moll, CF Sing
Arteriosclerosis (Dallas, Tex.) 1983
Arterial Pollution
H Peeters, GA Gresham, R Paoletti
1983
Plasma lipoproteins in familial combined hyperlipidemia and monogenic familial hypertriglyceridemia
JD Brunzell, JJ Albers, A Chait, SM Grundy, E Groszek, GB McDonald
Journal of lipid research 1983
Significance of low density lipoprotein production in the regulations of plasma cholesterol level in man
YA Kesaniemi, SM Grundy
Journal of Clinical Investigation 1982
Fettstoffwechselstörungen bei Nierenkrankheiten — Pathogenetische Mechanismen
WH Hörl, M Hörl, A Heidland
Klinische Wochenschrift 1982
Genetic mediation of cholesterol metabolism in the baboon (Papio cynocephalus)
BL Flow, GE Mott
Atherosclerosis 1982
Predictors of outcome in a risk factor intervention trial using behavior modification
DA Streja, E Boyko, SW Rabkin
Preventive Medicine 1982
Clustering and interrelationships of high-, low-, and very low-density lipoproteins in randomly recalled children and adults: The Cincinnati lipid research clinic's princeton school prevalence study
PS Gartside, JA Morrison, P Khoury, MJ Mellies, KA Kelly, CJ Glueck
Preventive Medicine 1982
The Cincinnati Lipid Research Clinic family study: cultural and biological determinants of lipids and lipoprotein concentrations
DC Rao, PM Laskarzewski, JA Morrison, P Khoury, K Kelly, R Wette, J Russell, CJ Glueck
The American Journal of Human Genetics 1982
Trials of structural exploratory data analysis
NE Morton, WR Williams, R Lew
The American Journal of Human Genetics 1982
Plasma lipid and lipoprotein concentrations in an Egyptian male sample
MI Shoukry, S Fareed
Lipids 1982
Tangier Disease with Normal Serum Cholesterol*
RW Frith, SF Hannan, JP Simcock, PJ Scott
Australian and New Zealand Journal of Medicine 1982
Type III hyperlipoproteinemia and atherosclerosis: A case report and re-evaluation
AM Gown, WR Hazzard, EP Benditt
Human Pathology 1982
Incorporation of cholesterol into serum high and low density lipoproteins
B Lundberg, M Lampero, L Suominen
Chemistry and Physics of Lipids 1982
Protection of myocardium by the compensatory mechanism of coronary collaterals after total occlusion of major coronary arteries shown in patients with familial hypercholesterolemia
PT Kuo, JB Kostis, AE Moreyra
American Heart Journal 1982
Lipoprotein Kinetics and Modeling
SM Grundy, GL Vega
Lipoprotein Kinetics and Modeling 1982
The Muscatine Cholesterol Family Study: Distribution of cholesterol levels within families of probands with high, low and middle cholesterol levels
KD Bucher, HG Schrott, WR Clarke, RM Lauer
Journal of Chronic Diseases 1982
Spouse concordance of plasma cholesterol and triglyceride
E Barrett-Connor, L Suarez, MH Criqui
Journal of Chronic Diseases 1982
Triglyceride and cholesterol metabolism in primary hypertriglyceridemia
U Beil, SM Grundy, JR Crouse, L Zech
Arteriosclerosis (Dallas, Tex.) 1982
Coronary artery disease mortality in relatives of hypertriglyceridemic school children: the Muscatine study
HG Schrott, WR Clarke, P Abrahams, DA Wiebe, RM Lauer
Circulation 1982
Risikofaktoren - Medizin
KD Bock
1982
Treatment of Hyperlipidemic Pancreatitis in Pregnancy With Total Parenteral Nutrition
RB Weinberg, MD Sitrin, GM Adkins, CC Lin
Gastroenterology 1982
Changes in the metabolism of fatty acids in adipose tissue in obese patients with primary hypertriacylglycerolemia
P Arner, P Engfeldt, J Ostman
Journal of lipid research 1982
A survey of 246 suggested coronary risk factors
PN Hopkins, RR Williams
Atherosclerosis 1981
The contrasting effects of a dietary soya lecithin product and corn oil on lipoprotein lipids in normolipidemic and familial hypercholesterolemic subjects
MT Childs, JA Bowlin, JT Ogilvie, WR Hazzard, JJ Albers
Atherosclerosis 1981
Relationships of gender, sex hormone use, and age with lipoprotein cholesterol/triglyceride ratios in an adult population The Pacific Northwest Bell Telephone Company health survey
RH Knopp, GR Warnick, CE Walden, PW Wahl, JJ Hoover, RO Bergelin, JT Ogilvie, JJ Albers, WR Hazzard
Atherosclerosis 1981
Genes and nutrition in the regulation of human lipoprotein metabolism
B Lewis
Klinische Wochenschrift 1981
The genetic component in coronary heart disease – a review
FW Robertson
Genetical Research 1981
Clustering and interrelationships of high, low, and very low-density lipoproteins in hypolipidemic children and adults: The Cincinnati lipid research clinic's Princeton school prevalence study
PS Gartside, JA Morrison, P Khoury, P Laskarzewski, CJ Glueck
Preventive Medicine 1981
Angiographic and risk factor characteristics of subjects with early onset ischaemic heart disease
S Nitter-Hauge, J Erikssen, E Thaulow, K Vatne
British heart journal 1981
Integrated regulation of very low density lipoprotein triglyceride and apolipoprotein-B kinetics in man: Normolipemic subjects, familial hypertriglyceridemia and familial combined hyperlipidemia
AH Kissebah, S Alfarsi, PW Adams
Metabolism 1981
Cholesterin und Triglyceride im Serum einer Münchner Bevölkerungsgruppe: Beziehungen zu Alter und Geschlecht
K Henze, A Wallmüller-Strycker, M Bauer, C Barth, G Wolfram, N Zöllner
Clinical Chemistry and Laboratory Medicine 1981
Genetic transmission of isoapolipoprotein E phenotypes in a large kindred: Relationship to dysbetalipoproteinemia and hyperlipidemia
WR Hazzard, GR Warnick, G Utermann, JJ Albers
Metabolism 1981
Hereditary aspects of coronary artery disease
RI Hamby
American Heart Journal 1981
Hormones, Lipoproteins and Atherosclerosis
L Winkler, B Schlag, R Dargel, G Stein, R Fünfstück
Hormones, Lipoproteins and Atherosclerosis 1981
Intermediate-density lipoprotein and cholesterol-rich very low density lipoprotein in angiographically determined coronary artery disease
R Tatami, H Mabuchi, K Ueda, R Ueda, T Haba, T Kametani, S Ito, J Koizumi, M Ohta, S Miyamoto, A Nakayama, H Kanaya, H Oiwake, A Genda, R Takeda
Circulation 1981
Regulation of Plasma Cholesterol by Lipoprotein Receptors
MS Brown, PT Kovanen, JL Goldstein
Science 1981
Influence of nicotinic acid on metabolism of cholesterol and triglycerides in man
SM Grundy, HY Mok, L Zech, M Berman
Journal of lipid research 1981
Zum praktischen Wert des Lymphozytenmodells f�r die pathogenetische Beurteilung einzelner Serumcholesterinfraktionen des Menschen bei der autosomal-monogenen Hypercholesterin�mie
T Wichmann, HA Freye, K Berndt
Human Genetics 1981
Familial combined hyperlipoproteinemia. Evidence for a role of growth hormone deficiency in effecting its manifestation
TJ Merimee
Journal of Clinical Investigation 1980
Kinetic bases of the primar hperlipidaemias: studies of apolipoprotein B turnover in geneticall defined subjects
ED Janus, AM Nicoll, PR Turner, P Magill, B Lewis
European Journal of Clinical Investigation 1980
High density lipoproteins during hypolipidemic therapy
MC Cheung, JJ Albers, PW Wahl, WR Hazzard
Atherosclerosis 1980
Very low density lipoprotein overproduction in genetic forms of hypertriglyceridaemia
A Chait, JJ Albers, JD Brunzell
European Journal of Clinical Investigation 1980
Association of coronary atherosclerosis with hyperapobetalipoproteinemia [increased protein but normal cholesterol levels in human plasma low density (beta) lipoproteins]
A Sniderman, S Shapiro, D Marpole, B Skinner, B Teng, PO Kwiterovich
Proceedings of the National Academy of Sciences 1980
Interrelationships among subgroups of serum lipoproteins in normal human subjects
RM Krauss, FT Lindgren, RM Ray
Clinica Chimica Acta 1980
Postprandial adipose tissue lipoprotein lipase activity in primary hypertriglyceridemia
AP Goldberg, A Chait, JD Brunzell
Metabolism 1980
CLOFIBRATE AND HYPERLIPIDAEMIA
H Keen, B Lewis, NE Miller, V Wynn
The Lancet 1980
Prevalence of coronary heart disease in the framingham offspring study: Role of lipoprotein cholesterols
PW Wilson, RJ Garrison, WP Castelli, M Feinleib, PM McNamara, WB Kannel
The American Journal of Cardiology 1980
Plasma Lipids
H Malmros
Plasma Lipids 1980
Sibling correlations and genetic estimates for selected blood variables in French Canadian children
C Bouchard, A Demirjian, E Mongeau
Human Genetics 1980
Genetic--epidemiologic study of early-onset ischemic heart disease
JJ Nora, RH Lortscher, RD Spangler, AH Nora, WJ Kimberling
Circulation 1980
Verhandlungen der Deutschen Gesellschaft für innere Medizin
B Schlegel
1980
Atherosclerosis V
AM Gotto, LC Smith, B Allen
1980
Clinical Applications of Cardiovascular Drugs
LS Dreifus, AN Brest
1980
Verhandlungen der Deutschen Gesellschaft für innere Medizin: 86. Kongreß, 13.–17. April 1980, Wiesbaden
B Schlegel
1980
Neonatal Screening for Inborn Errors of Metabolism
H Bickel, R Guthrie, G Hammersen
1980
Biliary lipid composition in normo- and hyperlipoproteinemia
J Ahlberg, B Angelin, K Einarsson, K Hellström, B Leijd
Gastroenterology 1980
Current Developments in Anthropological Genetics
JH Mielke, MH Crawford
1980
Effects of cholic acid on the metabolism of endogenous plasma triglyceride and on biliary lipid composition in hyperlipoproteinemia
B Angelin, B Leijd
Journal of lipid research 1980
Prediction of the parameters of whole body cholesterol metabolism in humans
DS Goodman, FR Smith, AH Seplowitz, R Ramakrishnan, RB Dell
Journal of lipid research 1980
Quantification of low density lipoprotein binding and cholesterol accumulation by single human fibroblasts using fluorescence microscopy
HS Kruth, M Vaughan
Journal of lipid research 1980
Defekte an Zellrezeptoren als Ursache endokriner und metabolischer Krankheiten
W Gerok
Klinische Wochenschrift 1979
Heterozygous familial hypercholesterolemia
C Gagné, S Moorjani, D Brun, M Toussaint, PJ Lupien
Atherosclerosis 1979
High and low density lipoprotein cholesterol levels in hypercholesterolemic school children
JA Morrison, I Groot, KA Kelly, BK Edwards, MJ Mellies, S Tillett, P Khoury, CJ Glueck
Lipids 1979
DIETARY FATS AND CORONARY HEART DISEASE: UNFINISHED BUSINESS
EH Ahrens
The Lancet 1979
Genetic and environmental variation in serum lipoproteins in relation to coronary heart disease
FW Robertson, AM Cumming
Journal of medical genetics 1979
The William Allan Memorial Award address: On phosphate transport and genetic screening. "Understanding backward--living forward" in human genetics
CR Scriver
The American Journal of Human Genetics 1979
Dalzeil's disease--66 years on
J Kyle
British medical journal 1979
Lipid-lipoprotein composition in hypercholesterolemic children and their parents
A Pagnan, M Vincenzi, E Barbieri, G Zanetti, P Guarini, CD Palu'
Atherosclerosis 1979
Nature of the familial influence on plasma lipid levels
D Hewitt, GJ Jones, GJ Godin, D Wraight, WC Breckenridge, JA Little, G Steiner, MA Mishkel
Atherosclerosis 1979
Analysis of genetic and environmental sources of variation in serum cholesterol in Tecumseh, Michigan. V. Variance components estimated from pedigrees
PP Moll, R Powsner, CF Sing
Annals of Human Genetics 1979
Adipose tissue lipoprotein lipase activity in type III hyperlipoproteinemia
AP Goldberg, DM Applebaum-Bowden, WR Hazzard
Metabolism 1979
Cultural and biological determinants of lipoprotein concentrations
DC Rao, NE Morton, CL Gulbrandsen, GG Rhoads, A Kagan, S Yee
Annals of Human Genetics 1979
Detection of rare major genes in lipid levels
J Ott
Human Genetics 1979
Use of combined diet and colestipol in long-term (7--7 1/2 years) treatment of patients with type II hyperlipoproteinemia
PT Kuo, K Hayase, JB Kostis, AE Moreyra
Circulation 1979
Increased coronary mortality in relatives of hypercholesterolemic school children: the Muscatine study
HG Schrott, WR Clarke, DA Wiebe, WE Connor, RM Lauer
Circulation 1979
Plasma lipoproteins, lipid transport, and atherosclerosis: recent developments
NE Miller
Journal of clinical pathology 1979
Genetic Diseases of the Skin
VM der Kaloustian, AK Kurban
1979
Hepatic cholesterol metabolism in normo- and hyperlipidemic patients with cholesterol gallstones
J Ahlberg, B Angelin, I Björkhem, K Einarsson, B Leijd
Journal of lipid research 1979
High and low density lipoprotein cholesterol levels in hypercholesterolemic school children
JA Morrison, I de Groot, KA Kelly, BK Edwards, MJ Mellies, S Tillett, P Khoury, CJ Glueck
Lipids 1979
Genetics of the low density lipoprotein receptor. Diminished receptor activity in lymphocytes from heterozygotes with familial hypercholesterolemia
DW Bilheimer, YK Ho, MS Brown, RG Anderson, JL Goldstein
Journal of Clinical Investigation 1978
Hyperlipidemia and premature arteriosclerosis
FR Smith
Lipids 1978
Regulation of cholesterol synthesis in the hyperlipoproteinaemias — Polymorphonuclear leucocyte abnormality specific to familial type II hypercholesterolaemia
WF Bremner, JL Third, B Clark, C Corstorphine, TD Lawrie
Atherosclerosis 1978
Cholesterol metabolism in man
SM Grundy
The Western journal of medicine 1978
Hypothesis into theory--the development of aetiological concepts of ischaemic heart disease: a review
B Lewis
Journal of the Royal Society of Medicine 1978
Medical and human genetics 1977: trends and directions
AG Motulsky
The American Journal of Human Genetics 1978
Pathophysiology of lipoprotein transport
JD Brunzell, A Chait, EL Bierman
Metabolism 1978
Plasma apoprotein and lipoprotein lipid levels in vegetarians
J Burslem, G Schonfeld, MA Howald, SW Weidman, JP Miller
Metabolism 1978
Achilles tendon thickness and ischemic heart disease in familial hypercholesterolemia
H Mabuchi, R Tatami, T Haba, K Ueda, R Ueda, S Ito, T Karnetani, J Koizurni, S Miyarnoto, M Ohta, R Takeda, T Takegoshi, H Takeshita
Metabolism 1978
CLOFIBRATE
B Lewis, N Miller, JD Brunzell, M Eastwood
The Lancet 1978
Homozygous familial hypercholesterolemia in Japan
H Mabuchi, R Tatami, T Haba, K Ueda, R Ueda, T Kametani, S Itoh, J Koizumi, M Oota, S Miyamoto, R Takeda, H Takeshita
The American Journal of Medicine 1978
Status of coronary heart disease risk factors
WB Kannel
Journal of Nutrition Education and Behavior 1978
Study of 100 Patients with Bilateral Sensorineural Hearing Loss for Lipid Abnormalities
LD Lowry, SR Isaacson
The Annals of otology, rhinology, and laryngology 1978
Hypothesis into Theory – the Development of Aetiological Concepts of Ischaemic Heart Disease: A Review
B Lewis
Journal of the Royal Society of Medicine 1978
Noninvasive evaluation of the patient with suspected coronary artery disease
JS Karliner
Current Problems in Cardiology 1978
Diet and sire effects on serum cholesterol and cholesterol absorption in infant baboons (Papio cynocephalus)
GE Mott, CA McMahan, HC McGill
Circulation research 1978
Bile acid kinetics in relation to endogenous tryglyceride metabolism in various types of hyperlipoproteinemia
B Angelin, K Einarsson, K Hellström, B Leijd
Journal of lipid research 1978
Segregation and linkage analyses of a large pedigree with hypertriglyceridemia
KK Namboodiri, RC Elston, C Hames, EA Murphy
American Journal of Medical Genetics 1977
DOSE-EFFECT RELATION OF CHOLESTYRAMINE IN CHILDREN AND YOUNG ADULTS WITH FAMILIAL HYPERCHOLESTEROLÆMIA
JR Farah, PO Kwiterovich, CA Neill
The Lancet 1977
Persistent echoes of the nature-nurture argument
B Childs
The American Journal of Human Genetics 1977
Commingling in distributions of lipids and related variables
NE Morton, CJ MacLean, A Kagan, CL Gulbrandsen, GG Rhoads, S Yee, R Lew
The American Journal of Human Genetics 1977
Cost/benefit analysis of treatment and prevention of myocardial infarction
S Cretin
Health Services Research 1977
Inheritance of type-III hyperlipoproteinemia. Lipoprotein patterns in first-degree relatives
B Vessby, H Hedstrand, LG Lundin, U Olsson
Metabolism 1977
Prevalence of serum lipid abnormalities in chronic hemodialysis
JD Brunzell, JJ Albers, LB Haas, AP Goldberg, L Agadoa, DJ Sherrard
Metabolism 1977
Familial hypercholesterolemia: Diagnosis, metabolic defect and management
RL Jackson, LC Smith, OD Taunton, AM Gotto
Life Sciences 1977
Plasma lipid changes in the female in aging and the menopause. Results from three population studies
A Svanborg, C Bengtsson, O Lindquist, S Roupe, B Steen
Clinica Chimica Acta 1977
Macromolecular dispersion of human plasma low-density lipoproteins in hyperlipoproteinemia
MG Hammond, MC Mengel, GL Warmke, WR Fisher
Metabolism 1977
Atherosclerosis: The low-density lipoprotein receptor hypothesis
JL Goldstein, MS Brown
Metabolism 1977
Plasma cholesterol and triglyceride levels in 6775 school children, ages 6–17
JA Morrison, I deGroot, BK Edwards, KA Kelly, JL Rauh, M Mellies, CJ Glueck
Metabolism 1977
Ascertainment in the sequential sampling of pedigrees
C Cannings, EA Thompson
Clinical Genetics 1977
In vitro regulation of cholesterol metabolism by low density lipoproteins in skin fibroblasts from hypo- and hyperresponding squirrel monkeys
LS Guertler, RW Clair
Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism 1977
Diet, heredity and heart disease
TD Lawrie, JL Third
Proceedings of the Nutrition Society 1977
GENETIC ANALYSIS OF THE NEPHROGENIC DIABETES INSIPIDUS DEFECT IN SWV MICE
NS Virgo, JR Miller
Canadian Journal of Genetics and Cytology 1977
Relationship between plasma lipid concentrations and coronary artery disease in 496 patients
AM Gotto, GA Gorry, JR Thompson, JS Cole, R Trost, D Yeshurun, ME DeBakey
Circulation 1977
The Cultured Cell and Inherited Metabolic Disease
RA Harkness, F Cockburn
1977
Diabetes mellitus • B
R Beckmann, M Berger, A Beringer, P Berchtold, J Beyer, A Bischoff, G Brehm, BF Clarke, GR Constam, LJ Duncan, FA Gries, A Hasselblatt, R Hild, K Irmscher, K Jahnke, J Kühnau, H Liebermeister, K Lundbaek, G Meyer-Schwickerath, S Napp-Mellinghoff, M Neubauer, F Nobbe, K Oberdisse, P Petrides, R Petzoldt, H Sauer, K Schöffling, M Spitznas, J Steinke, M Vogel, KH Vogelberg, A Wessing
1977
Coronary artery disease and its risk factors in families of young men with angina pectoris and in controls
AM Rissanen, EA Nikkila
Heart (British Cardiac Society) 1977
Monogenic disorders
CO Carter
Journal of medical genetics 1977
Medico-Social Management of Inherited Metabolic Disease
DN Raine
1977
Bile Acid Metabolism in Hyperlipoproteinaemia
K Hellström, K Einarsson
1977
Mechanism of induction of 3-hydroxy-3-methylglutaryl coenzyme A reductase in human leukocytes
AM Fogelman, J Seager, PA Edwards, G Popják
The Journal of biological chemistry 1977
Diet, energy balance, and genes--and serum cholesterol.
British medical journal 1977
Parameters of the three-pool model of the turnover of plasma cholesterol in normal and hyperlipidemic humans
FR Smith, RB Dell, RP Noble, DS Goodman
Journal of Clinical Investigation 1976
Analbuminemia in an American Indian girl
H Boman, M Hermodson, CA Hammond, AG Motulsky
Clinical Genetics 1976
Inheritance of xanthomatosis and hyper-β-lipoproteinaemia: A study of 7 large kind reds
A Heiberg
Clinical Genetics 1976
Prenatal diagnosis of homozygous familial hypercholesterolemia: Investigation of a case at risk
TF Wienker, G Utermann, HH Ropers
Clinical Genetics 1976
The common hyperlipidaemias
B Lewis
Postgraduate medical journal 1976
Physiological and analytical variation in cholesterol and triglycerides
GR Warnick, JJ Albers
Lipids 1976
Delayed clearance of chylomicron remnants following vitamin-A-containing oral fat loads in broad-β disease (type III hyperlipoproteinemia)
WR Hazzard, EL Bierman
Metabolism 1976
Halofenate in the treatment of type II hyperlipoproteinemia Double blind comparison with clofibrate
ED Rees, RD Hamilton, IF Kanner, S Wasson, T Hearn
Atherosclerosis 1976
Triglyceride accumulation in cultured human fibroblasts
BV Howard, WJ Howard, MD la Llera, NA Kefalides
Atherosclerosis 1976
Low density lipoprotein metabolism in a family of familial hypercholesterolemic patients
CJ Packard, JL Third, J Shepherd, AR Lorimer, HG Morgan, TD Lawrie
Metabolism 1976
Myocardial infarction in the familial forms of hypertriglyceridemia
JD Brunzell, HG Schrott, AG Motulsky, EL Bierman
Metabolism 1976
Thyrotropin levels in hyperlipidemic survivors of myocardial infarction
WL Green, WR Hazzard, JM Hershman
Metabolism 1976
The inheritance of hyperipoproteinaemia with xanthomatosis:A study of 132 kindreds
A Heiberg, K Berg
Clinical Genetics 1976
Maximal exercise stress testing in normal and hyperlipidemic children
FW James, CJ Glueck, RW Fallat, F Millett, S Kaplan
Atherosclerosis 1976
Cerebrotendinous cholestanolosis in relation to other cerebral xanthomatoses
JG Jong, CM Gent, JW Delleman
Clinical Neurology and Neurosurgery 1976
Nutrition Longevity, and Aging
LF Jakubczak
Nutrition Longevity, and Aging 1976
Combined para-aminosalicylic acid and dietary therapy in long-term control of hypercholesterolemia and hypertriglyceridemia (Types IIa and IIb hyperlipoproteinemia)
PT Kuo, WC Fan, JB Kostis, K Hayase
Circulation 1976
Low Density Lipoproteins
CE Day, RS Levy
1976
The Year in Metabolism 1975–1976
N Freinkel
1976
Fettstoffwechsel
G Assmann, J Augustin, E Baraona, HU Benz, W Brech, WV Brown, RJ Desnick, WR Fallat, S Ford, D Fredrickson, CJ Glueck, H Greten, K Harzer, P Herbert, GM Kostner, W Krivit, RI Levy, CS Lieber, M Liersch, G Middelhoff, GL Mills, NB Myant, RF ODea, J Papenberg, H Pilz, HM Rauen, S Sailer, G Schettler, G Schlierf, H Schriewer, D Seidel, J Slack, E Stange, O Stein, Y Stein, D Steinberg, A Weizel, H Wieland
1976
Screening for familial hyper-beta-lipoproteinaemia in children in hospital
JV Leonard, AS Fosbrooke, JK Lloyd, OH Wolff
Archives of disease in childhood 1976
Genetics of ischaemic heart disease
FH Epstein
Postgraduate medical journal 1976
The Hepatobiliary System
W Taylor
1976
Cholesterol metabolism in groups of rhesus monkeys with high or low response of serum cholesterol to an atherogenic diet
DA Eggen
Journal of lipid research 1976
Effects of polyunsaturated fats on lipid metabolism in patients with hypertriglyceridemia
SM Grundy
Journal of Clinical Investigation 1975
Differences among Hyperlipoproteinaemic Subjects in the Response of Lipoprotein Lipids to Resin Therapy
NE Miller, PJ Nestel
European Journal of Clinical Investigation 1975
EFFECTS OF INTRAVENOUS HYPERALIMENTATION ON PLASMA-LIPOPROTEINS IN SEVERE FAMILIAL HYPERCHOLESTEROLÆMIA
H Torsvik, JE Fischer, HA Feldman, RS Lees
The Lancet 1975
Bivariate analyses of cholesterol and triglyceride levels in families in which probands have type IIb lipoprotein phenotype
KK Namboodiri, RC Elston, CJ Glueck, R Fallat, CR Buncher, R Tsang
The American Journal of Human Genetics 1975
Analysis of genetic and environmental sources of variation in serum cholesterol in Tecumseh, Michigan. I. Analysis of the frequency distribution for evidence of a genetic polymorphism
CF Sing, MA Chamberlain, WD Block, S Feiler
The American Journal of Human Genetics 1975
Genetic heterogeneity in familial hypercholesterolemia: evidence for two different mutations affecting functions of low-density lipoprotein receptor
JL Goldstein, SE Dana, GY Brunschede, MS Brown
Proceedings of the National Academy of Sciences 1975
Lipidkonstellation in der Betalipoproteinfraktion der primären Typ II-Hyperlipoproteinämie
H Haacke, MR Parwaresch, C Mäder
Klinische Wochenschrift 1975
Reversible abnormalities in postheparin lipolytic activity during the late phase of release in diabetes mellitus (postheparin lipolytic activity in diabetes)
JD Brunzell, D Porte, EL Bierman
Metabolism 1975
Dose-response effect of single and combined clofibrate (Atromidin®) and niceritrol (perycit®) treatment on serum lipids and lipoproteins in type II hyperlipoproteinaemia
AG Olsson, Orö, S Rössner
Atherosclerosis 1975
Variability of polymorphic cellular enzymes in medical students with different serum lipid levels: A preliminary survey
MH Fox, HC Dessauer, SR Srinivasan, TF Thurmon, GS Berenson
Clinica Chimica Acta 1975
Broad-β disease versus endogenous hypertriglyceridemia: Levels and lipid composition of chylomicrons and very low density lipoproteins during fat-free feeding and alimentary lipemia
WR Hazzard, EL Bierman
Metabolism 1975
The Lipoprotein and Lipid Pattern in Xanthomatosis
A Heiberg
Acta Medica Scandinavica 1975
Mechanisms of cholesterol accumulation in the arterial wall
DB Zilversmit
The American Journal of Cardiology 1975
Familial hypercholesterolemia
JL Goldstein, MS Brown
The American Journal of Medicine 1975
Prospects for genetic screening
B Childs
The Journal of Pediatrics 1975
Risk factors for coronary artery disease in children of affected families
S Blumenthal, MJ Jesse, CH Hennekens, BE Klein, PL Ferrer, JE Gourley
The Journal of Pediatrics 1975
The Pediatric Roots of Coronary Heart Disease
JJ Nora, AH Nora
Chest 1975
It's time to be practical
DS Fredrickson
Circulation 1975
Hypolipidemic Agents
D Kritchevsky
1975
Lipids, Lipoproteins, and Drugs
D Kritchevsky, R Paoletti, WL Holmes
1975
Familial Hypercholesterolemia (One Form of Familial Type II Hyperlipoproteinemia) A STUDY OF ITS BIOCHEMICAL, GENETIC, AND CLINICAL PRESENTATION IN CHILDHOOD
PO Kwiterovich, DS Fredrickson, RI Levy
Journal of Clinical Investigation 1974
Assay of Total Plasma Apolipoprotein B Concentration in Human Subjects
G Schonfeld, RS Lees, PK George, B Pfleger
Journal of Clinical Investigation 1974
Combined hyperlipoproteinemia Evidence for a new lipoprotein phenotype
HG Rose, P Kranz, M Weinstock, J Juliano, JI Haft
Atherosclerosis 1974
Adaptive Responses in Hepatic and Intestinal Cholesterogenesis Following Ileal Resection in the Rat
HJ Weis, JM Dietschy
European Journal of Clinical Investigation 1974
Plasma lipid levels and coronary heart disease in adult relatives of newborns with normal and elevated cord blood lipids
JL Goldstein, JJ Albers, HG Schrott, WR Hazzard, EL Bierman, AG Motulsky
The American Journal of Human Genetics 1974
Linkage studies in a large kindred with familial hypercholesterolemia
J Ott, HG Schrott, JL Goldstein, WR Hazzard, FH Allen, CT Falk, AG Motulsky
The American Journal of Human Genetics 1974
Homozygous familial hypercholesterolemia: specificity of the biochemical defect in cultured cells and feasibility of prenatal detection
JL Goldstein, MJ Harrod, MS Brown
The American Journal of Human Genetics 1974
Effect of phenformin on lipid transport in hypertriglyceridemia
RW Stout, JD Brunzell, D Porte, EL Bierman
Metabolism 1974
Genetic Models in Biomedical Investigation
HL Bleich, ES Boro, H Valtin
New England Journal of Medicine 1974
Treatment of Hyperlipidemia
RI Levy, J Morganroth, BM Rifkind
New England Journal of Medicine 1974
Brave New World?: Current approaches to prevention, treatment, and research of genetic diseases raise ethical issues
AG Motulsky
Science 1974
Hyperlipidemia in Coronary Heart Disease I. LIPID LEVELS IN 500 SURVIVORS OF MYOCARDIAL INFARCTION
JL Goldstein, WR Hazzard, HG Schrott, EL Bierman, AG Motulsky
Journal of Clinical Investigation 1973
Hyperlipidemia in Coronary Heart Disease III. EVALUATION OF LIPOPROTEIN PHENOTYPES OF 156 GENETICALLY DEFINED SURVIVORS OF MYOCARDIAL INFARCTION
WR Hazzard, JL Goldstein, MG Schrott, AG Motulsky, EL Bierman
Journal of Clinical Investigation 1973
Familial hypercholesterolemia: identification of a defect in the regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity associated with overproduction of cholesterol
JL Goldstein, MS Brown
Proceedings of the National Academy of Sciences 1973
Advances in Lipid Research
AM Scanu
Advances in Lipid Research 1965
DIET AND ATHEROSCLEROSIS
AR Walker
The Lancet 1955
Arteriosclerosis
R Gubner, HE Ungerleider
The American Journal of Medicine 1949
Oxidative stress, biochemical alterations, and hyperlipidemia in female rats induced by lead chronic toxicity during puberty and post puberty periods
Annabi Alya, Dhouib Bini Ines, Lasram Montassar, Gharbi Najoua, El Fazâa Saloua
Iranian Journal of Basic Medical Sciences
A Mouse Model with Features of Familial Combined Hyperlipidemia
L Masucci-Magoulas, IJ Goldberg, CL Bisgaier, H Serajuddin, OL Francone, JL Breslow, AR Tall
Science 1997
Treatment of Hypercholesterolemia
JP Kane, MJ Malloy
Medical Clinics of North America 1982
Hypertriglyceridemia: Mechanisms, Clinical Significance, and Treatment
SM Grundy
Medical Clinics of North America 1982
Birth Defects Compendium
D Bergsma
Birth Defects Compendium 1979
Hyperlipidemia and Coronary Artery Disease: Principles of Diet and Drug Treatment
PT Kuo
Medical Clinics of North America 1974
Genetic Aspects of Hyperlipidemia in Coronary Heart Disease
JL Goldstein
Hospital Practice 1973

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