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Research Article Free access | 10.1172/JCI107234
Department of Pathology, New York University School of Medicine, New York 10016
Department of Biochemistry, Scripps Clinic and Research Foundation, and Division of Pediatric Hematology, University of California at San Diego, La Jolla, California 92037
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Department of Pathology, New York University School of Medicine, New York 10016
Department of Biochemistry, Scripps Clinic and Research Foundation, and Division of Pediatric Hematology, University of California at San Diego, La Jolla, California 92037
Find articles by Liem, H. in: JCI | PubMed | Google Scholar
Department of Pathology, New York University School of Medicine, New York 10016
Department of Biochemistry, Scripps Clinic and Research Foundation, and Division of Pediatric Hematology, University of California at San Diego, La Jolla, California 92037
Find articles by Knight, S. in: JCI | PubMed | Google Scholar
Department of Pathology, New York University School of Medicine, New York 10016
Department of Biochemistry, Scripps Clinic and Research Foundation, and Division of Pediatric Hematology, University of California at San Diego, La Jolla, California 92037
Find articles by Cox, K. in: JCI | PubMed | Google Scholar
Department of Pathology, New York University School of Medicine, New York 10016
Department of Biochemistry, Scripps Clinic and Research Foundation, and Division of Pediatric Hematology, University of California at San Diego, La Jolla, California 92037
Find articles by Muller-Eberhard, U. in: JCI | PubMed | Google Scholar
Published March 1, 1973 - More info
Sites of synthesis of hemopexin and transferrin were determined by culturing various tissues of rabbits and monkeys in the presence of labeled amino acids. Labeling of the serum proteins was examined by means of autoradiographs of immunoelectrophoretic patterns as well as by precipitation in the test tubes employing immunospecific antisera. Good correlation was seen between the results obtained by the two different methods. The liver was found to be the only site of many tissues studied that synthesized hemopexin. Transferrin production was observed in the liver, submaxillary gland, lactating mammary gland, testis, and ovary.
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