Mechanisms of Lithogenic Bile Formation in American Indian Women with Cholesterol Gallstones

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Abstract

Hepatic secretions of biliary lipids were estimated in 43 patients with and without cholesterol gallstones. Studies were carried out by a marker dilution technique employing duodenal intubation with a three-lumen tube. Hourly secretion rates of cholesterol, bile acids, and phospholipids were determined during constant infusion with liquid formula.

Authors

Scott M. Grundy, Allan L. Metzger, Ronald D. Adler