In vivo and in vitro studies of granulocyte chemotaxis were performed in three patients with the Chediak-Higashi syndrome. Rebuck skin windows showed a decreased accumulation of leukocytes at an inflammatory site. Studies in Boyden chambers documented a cellular defect in granulocyte chemotaxis. The chemotactic response of Chediak-Higashi cells by this technique averaged approximately 40% of normal and was consistently reduced using several different chemotactic stimuli. This deficit was magnified by shortening the chamber incubation time or by decreasing the pore size of the micropore filter and was independent of granulocytopenia. No abnormalities of passive motility, adhesiveness, viability, or pH optimum for migration were found in these cells. Chediak-Higashi serum contained no inhibitors of chemotaxis and was capable of generating normal amounts of chemotactic factors with the exception of one patient with the accelerated phase of the disease. Heterozygotes for the Chediak-Higashi trait had normal chemotactic function. This cellular defect in chemotaxis may contribute to the marked susceptibility to pyogenic infections which is so characteristic of patients with the Chediak-Higashi syndrome.
Robert A. Clark, Harry R. Kimball
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The lysosomal trafficking regulator “LYST”: an 80-year traffic jam
Turner ME, Che J, Mirhaidari GJ, Kennedy CC, Blum KM, Rajesh S, Zbinden JC, Breuer CK, Best CA, Barker JC |
Frontiers in immunology | 2024 |
Primary and Secondary Immunodeficiency: A Case-Based Guide to Evaluation and Management
JA Bernstein |
2021 | |
Chediak-Higashi syndrome: A review of the past, present, and future
P Sharma, ER Nicoli, J Serra-Vinardell, M Morimoto, C Toro, MC Malicdan, WJ Introne |
Drug discovery today. Disease models | 2019 |
The effect of color type on early wound healing in farmed mink (Neovison vison)
A Jespersen, HE Jensen, JF Agger, PM Heegaard, P Damborg, B Aalbæk, AS Hammer |
BMC veterinary research | 2017 |
On the move, lysosomal CAX drives Ca 2+ transport and motility
E Lloyd-Evans |
The Journal of Cell Biology | 2016 |
Congenital Defects in Neutrophil Dynamics
M Keszei, LS Westerberg |
Journal of Immunology Research | 2014 |
Primary Immunodeficiency Disorders
M Berger, ER Stiehm |
2014 | |
Pathologie
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Der Pathologe | 2013 |
Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases
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Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases | 2010 |
Effect of a thiol proteinase inhibitor, E-64-d, on susceptibility to infection with Staphylococcus aureus in Chediak–Higashi syndrome (beige) mice
M Morimoto, F Tanabe, H Kasai, M Ito |
International Immunopharmacology | 2007 |
Pediatric Infectious Diseases Revisited
H Schroten, S Wirth |
2007 | |
Two novel CHS1 (LYST) mutations: Clinical correlations in an infant with Chediak–Higashi syndrome
W Zarzour, R Kleta, H Frangoul, P Suwannarat, A Jeong, SY Kim, AS Wayne, M Gunay-Aygun, J White, AH Filipovich, WA Gahl |
Molecular Genetics and Metabolism | 2005 |
Lung Biology in Health and Disease: Cellular and Molecular Mechanisms
E Sapey, R Stockley |
Lung Biology in Health and Disease: Experimental Models and Therapeutic Potential | 2005 |
An Allele-Specific Genotyping Method for Rat Lyst (Lysosomal Trafficking Regulator) Gene
N MASUI, M MORI, T NISHIKAWA, Y TAKAGI, H ASAI, M YANABE, K YAMASAKI, T SERIKAWA, K SATO |
Experimental Animals | 2004 |
Participation of macrophages in atherosclerotic lesion morphology in LDLr −/− mice
NK Schiller, AS Black, GP Bradshaw, DJ Bonnet, LK Curtiss |
Journal of lipid research | 2004 |
Recent Advances in the Pathophysiology of COPD
TT Hansel, PJ Barnes |
2004 | |
Infections in patients with inherited defects in phagocytic function
T Andrews, KE Sullivan |
Clinical microbiology reviews | 2003 |
Systemic disease and periodontitis: manifestations of neutrophil dysfunction
DE Deas, SA Mackey, HT McDonnell |
Periodontology 2000 | 2003 |
Altered chemotactic behavior of crevicular PMNs in different forms of periodontitis
B Sigusch, S Eick, W Pfister, G Klinger, E Glockmann |
Journal of Clinical Periodontology | 2001 |
Influences of systemic diseases on periodontitis in children and adolescents
J Meyle, JR Gonzales |
Periodontology 2000 | 2001 |
Identification of a Novel Lipopolysaccharide-Inducible Gene with Key Features of Both a Kinase Anchor Proteins and chs1/beige Proteins
JW Wang, J Howson, E Haller, WG Kerr |
Journal of immunology (Baltimore, Md. : 1950) | 2001 |
Features of Severe Periodontal Disease in a Teenager With Chédiak-Higashi Syndrome
EM Delcourt-Debruyne, HR Boutigny, HF Hildebrand |
Journal of Periodontology | 2000 |
Immunodeficiency Diseases Caused by Defects in Phagocytes
IR Mackay, FS Rosen, JA Lekstrom-Himes, JI Gallin |
New England Journal of Medicine | 2000 |
PRIMARY PHAGOCYTIC DISORDERS OF CHILDHOOD
BH Segal, SM Holland |
Pediatric Clinics of North America | 2000 |
Blood and lymphoreticular disorders
D Kinane |
Periodontology 2000 | 1999 |
Clinical, Molecular, and Cell Biological Aspects of Chediak–Higashi Syndrome
W Introne, RE Boissy, WA Gahl |
Molecular Genetics and Metabolism | 1999 |
Genetic defects in Chediak-Higashi syndrome and the beige mouse
R A Spritz |
Journal of Clinical Immunology | 1998 |
Genetic and physical mapping of the Chediak-Higashi syndrome on chromosome 1q42-43
FJ Barrat, L Auloge, E Pastural, RD Lagelouse, E Vilmer, AJ Cant, J Weissenbach, DL Paslier, A Fischer, GS saint Basile |
The American Journal of Human Genetics | 1996 |
pH Changes Observed in the Inflamed Gingival Crevice Modulate Human Polymorphonuclear Leukocyte Activation In Vitro
B Leblebicioglu, JS Lim, AC Cario, FM Beck, JD Walters |
Journal of Periodontology | 1996 |
Host Defensive Functions in a Family Manifesting Early-Onset Periodontitis*
H Arai, T Chihara, K Takahashi, A Nagai, I Akutsu, S Takashiba, F Nishimura, H Kurihara, Y Murayama |
Journal of Periodontology | 1996 |
Adult Chédiak-Higashi syndrome presenting as parkinsonism and dementia
E Uyama, T Hirano, K Ito, H Nakashima, M Sugimoto, M Naito, M Uchino, M Ando |
Acta Neurologica Scandinavica | 1994 |
Neutrophil lysosomal nonoxidative microbicidal proteins in early-onset periodontitis
TF Flemmig, KT Miyasaki |
Oral Microbiology and Immunology | 1994 |
Acute necrotizing ulcerative gingivitis: risk factors involving host defense mechanisms
Y Murayama, H Kurihara, A Nagai, D Dompkowski, TE van Dyke |
Periodontology 2000 | 1994 |
Chemotaxis of polymorphonuclear neutrophils (PMN) in patients suffering from recurrent infection
H Brenneis, A Schmidt, P Blaas-Mautner, I Wörner, R Ludwig, GM Hansch |
European Journal of Clinical Investigation | 1993 |
Chediak-Higashi Syndrome: Report on Five Saudi Arab Children and Review of the Literature
AA Al-Nasser, HA Harfi, RS Sabbah, SM Malik |
Annals of Saudi medicine | 1993 |
Increased oxidative product formation by peripheral blood polymorphonuclear leukocytes in human periodontal diseases
S Kimura, T Yonemura, H Kaya |
Journal of Periodontal Research | 1993 |
Chediak-Higashi Syndrome in a Black Child
LL Anderson, AS Paller, D Malpass, ML Schmidt, TG Berger |
Pediatric Dermatology | 1992 |
Restoration of the defective natural defence of beige mice against tissue-migrating larvae of Strongyloides ratti by transfer with normal peritoneal cells
T Abe, K Yoshimura, Y Nawa |
International Journal for Parasitology | 1992 |
Defective in vitro motility of polymorphonuclear leukocytes of homozygote and heterozygote Chediak-Higashi cats
SP Colgan, AM Blancquaert, MA Thrall, WJ Bruyninckx |
Veterinary Immunology and Immunopathology | 1992 |
Flow cytometric evaluation of phagocytosis by peripheral blood polymorphonuclear leucocytes in human periodontal diseases
S Kimura, T Yonemura, T Hiraga, H Okada |
Archives of Oral Biology | 1992 |
Chediak-Higashi lymphoblastoid cell lines: Granule characteristics and expression of lysosome-associated membrane proteins
KL Jones, RM Stewart, M Fowler, M Fukuda, RF Holcombe |
Clinical Immunology and Immunopathology | 1992 |
Ergebnisse der Inneren Medizin und Kinderheilkunde/Advances in Internal Medicine and Pediatrics
M Brandis, A Fanconi, P Frick, K Kochsiek, EO Riecken |
1992 | |
Phagocyte function in juvenile periodontitis
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Infection and immunity | 1990 |
Fc and C3bi receptors and the differentiation antigen BH2-Ag are randomly distributed in the plasma membrane of locomoting neutrophils
B Pytowski, FR Maxfield, J Michl |
The Journal of Cell Biology | 1990 |
Macrophages and Polymorphonuclear Neutrophils in Lung Defense and Injury
Y Sibille, HY Reynolds |
American journal of respiratory and critical care medicine | 1990 |
Pulmonary infection following exodontia in a patient with glycoprotein-180 deficiency
MR Stevens, RW Kaplan |
Journal of Oral and Maxillofacial Surgery | 1990 |
Neutrophil Function And Oral Disease
TE van Dyke, GA Hoop |
Critical Reviews in Oral Biology & Medicine | 1990 |
Pulmonary manifestations of immune deficiency diseases
JL Sotomayor, RW Wilmott, SD Douglas |
Pediatric Pulmonology | 1989 |
Effect of plaque removal on patients with acute leukemia
B Ellegaard, OJ Bergmann, J Ellegaard |
Journal of Oral Pathology and Medicine | 1989 |
Neutrophil chemotactic behaviour in patients with early-onset forms of periodontitis. (I). Leading front analysis in Boyden chambers
DF Kinane, CF Cullen, FA Johnston, CW Evans |
Journal of Clinical Periodontology | 1989 |
The Beige Mouse: Role of Neutrophil Elastase in the Development of Pulmonary Emphysema
B Starcher, I Williams |
Experimental Lung Research | 1989 |
Paleopathology inAustralopithecus africanus: A suggested case of a 3-million-year-old prepubertal periodontitis
U Ripamonti |
American Journal of Physical Anthropology | 1988 |
Chemotaxis in the elderly: Modifications after the intake of ascorbic acid and levamisole
MA Muniain, C Rodrigues, F Pozuelo, A Romero, R Mata, J Perez-Venegas, D Rodriguez, M Garrido |
AGE | 1988 |
Rapid down-regulation of protein kinase C in (chediak-higashi syndrome) beige mouse by phorbol ester
M Ito, F Tanabe, Y Takami, A Sato, S Shigeta |
Biochemical and Biophysical Research Communications | 1988 |
Impaired natural defence of beige (Chediak-Higashi syndrome) mice against tissue-migrating larvae of Strongyloides ratti and its reconstitution by bone marrow cells
Y Nawa, T Abe, J Imai, H Maruyama |
Parasite Immunology | 1988 |
Neutrophil Granule Constituents and Their Release in Health and Disease
LA Boxer, JE Smolen |
Hematology/Oncology Clinics of North America | 1988 |
Phagocytes and Disease
MS Klempner, B Styrt, J Ho |
1988 | |
Patients With Bone Marrow Failure Demonstrate Decreased Cutaneous Reactivity to Human C5a
KB Yancey, L Bielory, R Wright, N Young, MM Frank, TJ Lawley |
Journal of Investigative Dermatology | 1987 |
Evaluation of Hepatic and Renal Function in Cats with Chediak-Higashi Syndrome
KJ Wardrop, CR Dhein, DJ Prieur, KM Meyers |
Veterinary Clinical Pathology | 1987 |
Oxygen radical generation by polymorphonuclear leucocytes of beige mice
A Kubo, M Sasada, T Nishimura, T Moriguchi, T Kakita, K Yamamoto, H Uchino |
Clinical & Experimental Immunology | 1987 |
Monocytes accumulate on Rebuck skin window coverslips but not in skin chamber fluid
W Zimmerli, JI Gallin |
Journal of Immunological Methods | 1987 |
Stimulation of 5-lipoxygenase activity in polymorphonuclear leukocytes of rats by caseinate treatment
WC Chang, GW Su |
Biochemical Pharmacology | 1987 |
Hyperactive phagocytosis by circulating neutrophils and monocytes in Chèdiak-Higashi syndrome
A Komiyama, H Saitoh, M Yamazaki, H Kawai, Y Miyagawa, T Akabane, M Ichikawa, H Shigematsu |
Scandinavian Journal of Haematology | 1986 |
Effect of human serum and some of its components on neutrophil adherence and migration across an epithelium
EB Cramer, LC Milks, MJ Brontoli, GK Ojakian, SD Wright, HJ Showell |
The Journal of Cell Biology | 1986 |
Chédiak-Higashi syndrome neutrophils are characterized by the absence of both normal azurophilic granules
BC West |
The American Journal of Pathology | 1986 |
Peripheral blood phagocyte function in acute necrotizing ulcerative gingivitis
N Claffey, R Russell, D Shanley |
Journal of Periodontal Research | 1986 |
Inherited Deficiency of the Seventh Component of Complement Associated with Meningococcal Meningitis: Lack of Serum Bactericidal Activity against Neisseria meningitidis in a Girl with C7 Deficiency and HLA Studies of a C7-Deficient Japanese Family
T Miyake, K Ohta, J Kawamori, T Hirao, Y Akagaki, S Inai |
Microbiology and Immunology | 1986 |
Host Factors in Juvenile Periodontitis
RB Cogen, JM Roseman, W Al-Joburi, WC Louv, RT Acton, BO Barger, RC Go, RA Rasmussen |
Journal of dental research | 1986 |
Selective immunoglobulin M deficiency associated with disseminated molluscum contagiosum
M Mayumi, K Yamaoka, T Tsutsui, H Mizue, A Doi, M Matsuyama, S Ito, K Shinomiya, H Mikawa |
European Journal of Pediatrics | 1986 |
HUMAN MONOCYTE AND NEUTROPHIL CHEMOTAXIS IN VITRO EMPLOYING 51Cr-LABELLED LEUKOCYTES
T Ternowitz |
Acta Pathologica Microbiologica Scandinavica Series C: Immunology | 1985 |
Defective neutrophil and monocyte motility in patients with early onset periodontitis
RC Page, TJ Sims, F Geissler, LC Altman, DA Baab |
Infection and immunity | 1985 |
Monocyte receptors for fibronectin characterized by a monoclonal antibody that interferes with receptor activity
B Hosein, C Bianco |
Journal of Experimental Medicine | 1985 |
An improved multimembrane microassay for quantitating the motility of granulocytes and monocytes labeled with chromium-51
TJ Sims, FT Geissler, RC Page |
Journal of Immunological Methods | 1985 |
Albinism
PE Kinnear, B Jay, CJ Witkop |
Survey of Ophthalmology | 1985 |
Morphological and Biochemical Responses of Leukocytes in Chemokinesis and Chemotaxis
H Keller, H Cottier |
Pathology - Research and Practice | 1985 |
Respiratory infections may reflect deficiencies in host defense mechanisms
HY Reynolds |
Disease-a-Month | 1985 |
In Vivo Assay of Crevicular Leukocyte Migration: Its Development and Potential Applications
VJ Iacono, S Singh, LM Golub, NS Ramamurthy, R Kaslick |
Journal of Periodontology | 1985 |
Enzyme activities involved in collagen and proteoglycan degradations in oral mucosas of beige (Chediak-Higashi syndrome) mice
H Shikata, N Utsumi, M Noguchi, T Asano, M Kashimata, M Hiramatsu, T Masumizu |
Archives of Dermatological Research | 1985 |
Immunologic Profile of Juvenile Periodontitis.* II. Neutrophil Chemotaxis, Phagocytosis and Spore Germination
JB Suzuki, BC Collison, WA Falkler, RK Nauman |
Journal of Periodontology | 1984 |
Recurrent pyoderma in a family with a defect in leucocyte locomotion
CC Zielinski, PA Dremsek, R Ahmad, MM Eibl |
British medical journal (Clinical research ed.) | 1984 |
Effect of Muramyl Dipeptide Analog on Salmonella enteritidis Infection in Beige Mice with Chediak-Higashi Syndrome
K Onozuka, T Saito-Taki, M Nakano |
Microbiology and Immunology | 1984 |
Immunodermatology
RE Schopf, M Jung, B Morsches, K Bork |
Immunodermatology | 1984 |
In Vivo Crevicular Leucocyte Response in Humans to a Chemotactic Challenge: Effects of Periodontal Diseases
S Singh, LM Golub, VJ Iacono, NS Ramamurthy, R Kaslick |
Journal of Periodontology | 1984 |
Regulation of Leukocyte Function
R Snyderman |
1984 | |
Heterogeneity of the molecular lesions in inherited phosphofructokinase deficiency
S Vora, M Davidson, C Seaman, AF Miranda, NA Noble, KR Tanaka, EP Frenkel, S Dimauro |
Journal of Clinical Investigation | 1983 |
Chemotaxis: Basic aspects of methodology, mechanisms and pathology
BM Czarnetzki, E Kownatzki, M Dierich, PC Frei |
Archives of Dermatological Research | 1983 |
Abnormal Polymorphonuclear Leukocyte Motility in Dermatologic Diseases
L Harvath |
Pediatric Dermatology | 1983 |
The Chediak-Higashi gene in humans. III. Studies on the mechanisms of NK impairment
JC Roder, RF Todd, P Rubin, T Haliotis, SL Helfand, J Werkmeister, HF Pross, LA Boxer, SF Schlossman, AS Fauci |
Clinical & Experimental Immunology | 1983 |
Suppressive effect of IgE soluble immune complex on neutrophil chemotaxis
S Ito, K Shinomiya, H Mikawa |
Clinical & Experimental Immunology | 1983 |
The role of cytoskeletal and cytocontractile elements in pathologic processes
E Rungger-Brändle, G Gabbiani |
The American Journal of Pathology | 1983 |
Chlorine-induced damage to surface adhesions during sublethal injury of enterotoxigenic Escherichia coli
SM Walsh, GK Bissonnette |
Applied and environmental microbiology | 1983 |
Review of neutrophil adherence, chemotaxis, phagocytosis and killing
GS Smith, JH Lumsden |
Veterinary Immunology and Immunopathology | 1983 |
Elevated antibody titers to Epstein-Barr virus and low natural killer cell activity in patients with Chediak-Higashi syndrome
F Merino, GO Klein, W Henle, P Ramirez-Duoue, M Forsgren, C Amesty |
Clinical Immunology and Immunopathology | 1983 |
Host Defenses to Intracellular Pathogens
TK Eisenstein, P Actor, H Friedman |
1983 | |
Vitiligo and Other Hypomelanoses of Hair and Skin
JP Ortonne, DB Mosher, TB Fitzpatrick |
1983 | |
Genetic disorders of leukocyte function: What they tell us about normal antimicrobial mechanisms of human phagocytic cells
RK Root, PB Beeson |
Klinische Wochenschrift | 1982 |
Host defenses against infection: importance of phagocytic mechanisms from the study of genetic disorders of leukocyte function
RK Root |
Bulletin of the New York Academy of Medicine | 1982 |
Distribution pattern of lysosomal granules in fibroblasts of the Chediak-Higashi syndrome
K Abe, S Arashima, M Honma |
Journal of clinical pathology | 1982 |
Increased leucoattractant binding and reversible inhibition of neutrophil motility mediated by the peroxidase/H2O2/halide system: effects of ascorbate, cysteine, dithiothreitol, levamisole and thiamine
R Anderson, PT Jones |
Clinical & Experimental Immunology | 1982 |
Tubulin tyrosinolation in human polymorphonuclear leukocytes: studies in normal subjects and in patients with the Chediak-Higashi syndrome
J Nath, M Flavin, JI Gallin |
The Journal of Cell Biology | 1982 |
In vivo crevicular leukocyte response to a chemotactic challenge: inhibition by experimental diabetes
LM Golub, GA Nicoll, VJ Iacono, NS Ramamurthy |
Infection and immunity | 1982 |
Human alveolar macrophages produce leukotriene B4
AO Fels, NA Pawlowski, EB Cramer, TK King, ZA Cohn, WA Scott |
Proceedings of the National Academy of Sciences | 1982 |
Juvenile periodontitis: an historical review
MS Saxby |
Journal of Oral Rehabilitation | 1982 |
The Cytology of Joint Exudates in Rheumatoid Arthritis:Morphology and Preparation Techniques
A Bjelle, B Norberg, G Sjögren |
Scandinavian Journal of Rheumatology | 1982 |
Bactericidal activity and chemotaxis in pemphigus vulgaris and bullous pemphigoid
AR Ahmed, BJ Ank, SE Gard, ER Stiehm |
Journal of the American Academy of Dermatology | 1982 |
Regression line analysis of neutrophil chemotaxis
TE Dyke, AA Reilly, RJ Genco |
Immunopharmacology | 1982 |
Biochemistry and Function of Phagocytes
F Rossi, P Patriarca |
1982 | |
Dissociated impairment of neutrophil functions and recurrent infections
C Chastel, P Youinou, MC Leglise, D L'Hostis, C Ferec |
Infection | 1982 |
Leukocyte Chemotaxis to the Dermal-Epidermal Junction of Human Skin Mediated by Pemphigoid Antibody and Complement: Mechanism of Cell Attachment in the in Vitro Leukocyte Attachment Method
WR Gammon, CC Merritt, DM Lewis, WM Sams, CE Wheeler, J Carlo |
Journal of Investigative Dermatology | 1981 |
Current Status of the Host Response in Chronic Marginal Periodontitis*
RC Page, HE Schroeder |
Journal of Periodontology | 1981 |
Fluidity properties and liquid composition of erythrocyte membranes in Chediak-Higashi syndrome
LM Ingraham, CP Burns, LA Boxer, RL Baehner, RA Haak |
The Journal of Cell Biology | 1981 |
Mast cell degranulation in beige mice with the Chédiak-Higashi defect
KC Poon, PI Liu, SS Spicer |
The American Journal of Pathology | 1981 |
The response of human sulcular leucocytes to a chemotactic challenge
LM Golub, VJ Iacono, G Nicoll, N Ramamurthy, RS Kaslick |
Journal of Periodontal Research | 1981 |
Chemotactic factor concentration gradients in chemotaxis assay systems
DA Lauffenburger, SH Zigmond |
Journal of Immunological Methods | 1981 |
Peripheral Blood Leukocyte Abnormalities and Periodontal Disease: A Family Study*
GE Vandesteen, LC Altman, RC Page |
Journal of Periodontology | 1981 |
Current Topics in Cellular Regulation
G Cahill, T Aoki, R Smith |
Current Topics in Cellular Regulation | 1981 |
Immunology of Human Infection
AJ Nahmias, RJ OReilly |
1981 | |
Immunologic Defects in Laboratory Animals 1
ME Gershwin, B Merchant |
1981 | |
Degranulating Stimuli Decrease the Negative Surface Charge and Increase the Adhesiveness of Human Neutrophils
JI Gallin |
Journal of Clinical Investigation | 1980 |
Pemphigoid Antibody Mediated Attachment of Peripheral Blood Leukocytes at the Dermal-Epidermal Junction of Human Skin
WR Gammon, DM Lewis, JR Carlo, WM Sams, CE Wheeler |
Journal of Investigative Dermatology | 1980 |
Role of transmethylation reactions in cellular motility and phagocytosis
R Snyderman, MC Pike, NM Kredich |
Molecular Immunology | 1980 |
Impairment of phagocytosis by heterophils from chickens during ochratoxicosis
CF Chang, PB Hamilton |
Applied and environmental microbiology | 1980 |
Effects of cigarette smoke and its constituents on the adherence of polymorphonuclear leukocytes
RB Bridges, L Hsieh, DG Haack |
Infection and immunity | 1980 |
Comparative stimulation of granulocyte adherence and chemotaxis by bacterial products
PJ Spagnuolo, JJ Ellner |
Infection and immunity | 1980 |
Transepithelial migration of human neutrophils: an in vitro model system
EB Cramer, LC Milks, GK Ojakian |
Proceedings of the National Academy of Sciences | 1980 |
Development of chemotactic responsiveness in myeloid precursor cells: studies with a human leukemia cell line
JA Fontana, DG Wright, E Schiffman, BA Corcoran, AB Deisseroth |
Proceedings of the National Academy of Sciences | 1980 |
Gingival crevice neutrophil function in periodontal lesions
PA Murray, MR Patters |
Journal of Periodontal Research | 1980 |
LEUKOCYTE MIGRATION IN DIFFERENT SYSTEMS
A Schreiner, T Kalager, D Vaula |
Acta Pathologica Microbiologica Scandinavica Section C Immunology | 1980 |
Letter to the Editors
JH Kraal, MP Ruben |
Journal of Periodontology | 1980 |
Modulation of human neutrophil and eosinophil polymorphonuclear leukocyte chemotaxis: An analytical review
FH Valone |
Clinical Immunology and Immunopathology | 1980 |
Ergebnisse der Inneren Medizin und Kinderheilkunde / Advances in Internal Medicine and Pediatrics
P Frick, GA von Harnack, GA Martini, A Prader, HP Wolff |
1980 | |
Biochemistry and Metabolism
AJ Sbarra, RR Strauss |
1980 | |
Defective phagocytosis confined to Staphylococcus aureus in a female infant with recurrent infections
S Ito, H Mikawa, T Hirao, T Yoshida, R Okuda |
European Journal of Pediatrics | 1980 |
Lithium Effects on Granulopoiesis and Immune Function
AH Rossof, WA Robinson |
1980 | |
Neutrophil Chemotaxis Dysfunction in Human Periodontitis
TE Dyke, HU Horoszewicz, LJ Cianciola, RJ Genco |
Infection and immunity | 1980 |
N -Formylmethionyl Peptide Receptors on Equine Leukocytes Initiate Secretion But Not Chemotaxis
R Snyderman, MC Pike |
Science | 1980 |
Impaired phagocytosis by heterophils from chickens during aflatoxicosis
CF Chang, PB Hamilton |
Toxicology and Applied Pharmacology | 1979 |
Phagocyte Chemotaxis
WR Gammon |
Journal of Investigative Dermatology | 1979 |
Impaired neutrophil chemotaxis in patients with juvenile and rapidly progessing periodontitis
WS Lavine, EG Maderazo, J Stolman, PA Ward, RB Cogen, I Greenblatt, PB Robertson |
Journal of Periodontal Research | 1979 |
Suppressive effect of IgA soluble immune complexes on neutrophil chemotaxis
S Ito, H Mikawa, K Shinomiya, T Yoshida |
Clinical & Experimental Immunology | 1979 |
Impaired neutrophil chemotaxis in Pelger-Huët anomaly
H Repo, P Vuopio, M Leirisalo, SE Jansson, TU Kosunen |
Clinical & Experimental Immunology | 1979 |
The Chediak-Higashi syndrome: quantitation of a deficiency in maximal bactericidal capacity
CC Clawson, JE Repine, JG White |
The American Journal of Pathology | 1979 |
Mannose-sensitive interaction of Escherichia coli with human peripheral leukocytes in vitro
DF Mangan, IS Snyder |
Infection and immunity | 1979 |
Mannose-sensitive stimulation of human leukocyte chemiluminescence by Escherichia coli
DF Mangan, IS Snyder |
Infection and immunity | 1979 |
The response of polymorphonuclear leukocytes to chemotictic stimulation for smokers and non-smokers
JH Kraal, EB Kenney |
Journal of Periodontal Research | 1979 |
DELAYED SEPARATION OF THE UMBILICAL CORD, WIDESPREAD INFECTIONS, AND DEFECTIVE NEUTROPHIL MOBILITY
AR Hayward, J Leonard, CB Wood, BA Harvey, MC Greenwood, JF Soothill |
The Lancet | 1979 |
Abnormal leukocyte electrophoretic mobility in myotonic dystrophy
AR Seay, FA Ziter, HR Hill |
Journal of the Neurological Sciences | 1979 |
Inborn Errors of Immunity and Phagocytosis
F Güttler, JW Seakins, RA Harkness |
1979 | |
Immune Deficiency
MD Cooper, AR Lawton, PA Miescher, HJ Mueller-Eberhard |
1979 | |
Role of secretory events in modulating human neutrophil chemotaxis
JI Gallin, DG Wright, E Schiffmann |
Journal of Clinical Investigation | 1978 |
ABNORMAL NEUTROPHIL CHEMOTAXIS IN A SYNDROME OF UNUSUAL FACIES, PROPORTIONATE SMALL STATURE AND SENSORINEURAL DEAFNESS-MUTISM
YH Thong, BS Douglas, A Ferrante |
Acta Paediatrica | 1978 |
Treatment of the immunodeficiency diseases — progress toward replacement therapy emphasizing cellular and macromolecular engineering
R Pahwa, S Pahwa, R O'Reilly, RA Good |
Springer Seminars in Immunopathology | 1978 |
Phagocytic defects
PG Quie, EL Mills, LC McPhail, RB Johnston |
Springer Seminars in Immunopathology | 1978 |
CHEMOTAXIS IN CUTANEOUS DISEASE
MV Dahl |
International Journal of Dermatology | 1978 |
Prostaglandins and Cyclic Nucleotides in the Chediak-Higashi Syndrome and Experimental Systemic Lupus Erythematosus
RB Zurier |
Journal of Investigative Dermatology | 1978 |
Lazy leucocyte syndrome--disorder of the granulocyte membrane?
PH Pinkerton, JB Robinson, JS Senn |
Journal of clinical pathology | 1978 |
The effect of acrylamide on human polymorphonuclear neutrophils in vitro
D Mangan, IS Snyder |
British journal of industrial medicine | 1978 |
Specific protease deficiency in polymorphonuclear leukocytes of Chédiak-Higashi syndrome and beige mice
JD Vassalli, A Granelli-Piperno, C Griscelli, E Reich |
Journal of Experimental Medicine | 1978 |
Defective neutrophil motility and recurrent infection. In vitro and in vivo effects of levamisole
AR Rabson, R Anderson, A Glover |
Clinical & Experimental Immunology | 1978 |
The Chédiak-Higashi syndrome. Evidence that defective leukotaxis is primarily due to an impediment by giant granules
CC Clawson, JG White, JE Repine |
The American Journal of Pathology | 1978 |
Immunocytochemical Identification of Azurophilic and Specific Granule Markers in the Giant Granules of Chediak-Higashi Neutrophils
PG Rausch, KB Pryzwansky, JK Spitznagel |
New England Journal of Medicine | 1978 |
Chronic Granulomatous Disease in Three Siblings
B Elgefors, S Olling, H Peterson |
Scandinavian Journal of Infectious Diseases | 1978 |
Microbial—Phagocytic Interactions
PG Quie, EL Mills |
Clinics in rheumatic diseases | 1978 |
Mechanism for the inflammatory response in primate lungs. Demonstration and partial characterization of an alveolar macrophage-derived chemotactic factor with preferential activity for polymorphonuclear leukocytes
JA Kazmierowski, JI Gallin, HY Reynolds |
Journal of Clinical Investigation | 1977 |
Effects of levamisole on normal and abnormal leukocyte locomotion
DG Wright, CH Kirkpatrick, JI Gallin |
Journal of Clinical Investigation | 1977 |
LYSOSOMES AND DERMATOLOGY
RB Zurier |
International Journal of Dermatology | 1977 |
Acute inflammation. A review
GB Ryan, G Majno |
The American Journal of Pathology | 1977 |
Effects of tobacco smoke on chemotaxis and glucose metabolism of polymorphonuclear leukocytes
RB Bridges, JH Kraal, LJ Huang, BM Chancellor |
Infection and immunity | 1977 |
Effects of cigarette smoke components on in vitro chemotaxis of human polymorphonuclear leukocytes
RB Bridges, JH Kraal, LJ Huang, MB Chancellor |
Infection and immunity | 1977 |
Defective neutrophil chemotaxis in juvenile periodontitis
RA Clark, RC Page, G Wilde |
Infection and immunity | 1977 |
Clinical conditions associated with defective polymorphonuclear leukocyte chemotaxis
PG Quie, KL Cates |
The American Journal of Pathology | 1977 |
Delayed hypersensitivity: indicator of acquired failure of host defenses in sepsis and trauma
JL Meakins, JB Pietsch, O Bubenick, R Kelly, H Rode, J Gordon, LD MacLean |
Annals of Surgery | 1977 |
Function of Neutrophils in Preleukaemia
P Ruutu, T Ruutu, P Vuopio, TU Kosunen, A la Chapelle |
Scandinavian Journal of Haematology | 1977 |
Cutaneous Manifestations of Defective Host Defenses
WL Weston |
Pediatric Clinics of North America | 1977 |
The Clinical and Laboratory Diagnosis of Chronic Granulomatous Disease of Childhood
BR Macpherson |
Critical Reviews in Clinical Laboratory Sciences | 1977 |
Disorders of Leukocyte Chemotaxis
R Snyderman, MC Pike |
Pediatric Clinics of North America | 1977 |
Biological Amplification Systems in Immunology
NK Day, RA Good |
1977 | |
Correction of characteristic abnormalities of microtubule function and granule morphology in Chediak-Higashi syndrome with cholinergic agonists
JM Oliver, RB Zurier |
Journal of Clinical Investigation | 1976 |
Defective neutrophil chemotaxis in bone marrow transplant patients
RA Clark, FL Johnson, SJ Klebanoff, ED Thomas |
Journal of Clinical Investigation | 1976 |
Impaired microtubule function correctable by cyclic GMP and cholinergic agonists in the Chediak-Higashi syndrome
JM Oliver |
The American Journal of Pathology | 1976 |
Effect of prophylactic colchicine therapy on leukocyte function in patients with familial mediterranean fever
CA Dinarello, MJ Chusid, AS Fauci, JI Gallin, DC Dale, SM Wolff |
Arthritis & Rheumatism | 1976 |
The steroid effect on the in vitro human neutrophil chemotactic response
JA Majeski, JW Alexander |
Journal of Surgical Research | 1976 |
A familial defect in cellular chemotaxis associated with redheadedness and recurrent infection
S Witemeyer, DE van Epps |
The Journal of Pediatrics | 1976 |
Defective neutrophil motility in children with measles
R Anderson, AR Rabson, R Sher, HJ Koornhof, D Bact |
The Journal of Pediatrics | 1976 |
Host Response in Chronic Periodontal Disease: V. The Dental and Periodontal Status of Mink and Mice Affected by Chediak-Higashi Syndrome*
WS Lavine, RC Page, GA Padgett |
Journal of Periodontology | 1976 |
Inflammation and Localization of Infection
GB Ryan |
Surgical Clinics of North America | 1976 |
Impaired Resistance to Infection
DM Whitten |
Clinics in Perinatology | 1976 |
Interaction of leukocyte chemotactic factors with the cell surface. I. Chemotactic factor-induced changes in human granulocyte surface charge
JI Gallin, JR Durocher, AP Kaplan |
Journal of Clinical Investigation | 1975 |
Growth characteristics of bone marrow cells from beige mutant, the mouse homologue of the Chediak-Highshi syndrome of man, propagated in semisolid agar cultures
HW Renshaw, WC Davis |
In Vitro | 1975 |
ABNORMALITIES OF LEUKOCYTE CHEMOTAXIS IN HUMAN DISEASE
R Snyderman, MC Pike, LC Altman |
Annals of the New York Academy of Sciences | 1975 |
Comparison of leukocyte count and function in smoking and nonsmoking young men
RC Noble, BB Penny |
Infection and immunity | 1975 |
Effects of serotonin, carbamylcholine, and ascorbic acid on leukocyte cyclic GMP and chemotaxis
JA Sandler, JI Gallin, M Vaughan |
The Journal of Cell Biology | 1975 |
Suppression of cellular immune responses following transfer factor: Report of a case
CH Kirkpatrick, JI Gallin |
Cellular Immunology | 1975 |
Opportunistic infection in children
RD Feigin, WT Shearer |
The Journal of Pediatrics | 1975 |
Evaluation of Infants and Children with Recurrent Infection
AJ Ammann, DW Wara |
Current Problems in Pediatrics | 1975 |
Kinetic analysis of chemotactic factor generation in human serum via activation of the classical and alternate complement pathways
JI Gallin, RA Clark, MM Frank |
Clinical Immunology and Immunopathology | 1975 |
Modulation of the inflammatory response by products released from human polymorphonuclear leukocytes during phagocytosis: Generation and inactivation of the chemotactic factor C5a
DG Wright, JI Gallin |
Inflammation | 1975 |
Leucocyte Chemotaxis: Physiological Considerations and Abnormalities
JI Gallin, SM Wolff |
Clinics in Haematology | 1975 |
Granulocytendysfunktion: II. Erworbene Störungen
D Niethammer, A Wildfeuer, E Kleihauer, O Haferkamp |
Klinische Wochenschrift | 1975 |
DEFECT IN NEUTROPHIL GRANULOCYTE CHEMOTAXIS IN JOB'S SYNDROME OF RECURRENT "COLD" STAPHYLOCOCCAL ABSCESSES
HR Hill, PG Quie, HF Pabst, HD Ochs, RA Clark, SJ Klebanoff, RJ Wedgwood |
The Lancet | 1974 |
RAISED SERUM-IgE LEVELS AND DEFECTIVE NEUTROPHIL CHEMOTAXIS IN THREE CHILDREN WITH ECZEMA AND RECURRENT BACTERIAL INFECTIONS
HR Hill, PG Quie |
The Lancet | 1974 |
Interactions of Antibodies, Complement Components and Various Cell Types in Immunity Against Viruses and Pyogenic Bacteria
AC Allison |
Immunological Reviews | 1974 |
Leukocyte dysfunction in the bovine homologue of the Chediak-Higashi syndrome of humans
HW Renshaw, WC Davis, HH Fudenberg, GA Padgett |
Infection and immunity | 1974 |
Leukotaxis and leukotactic disorders. A review
PA Ward |
The American Journal of Pathology | 1974 |
The regulatory role of divalent cations in human granulocyte chemotaxis. Evidence for an association between calcium exchanges and microtubule assembly
JI Gallin, AS Rosenthal |
The Journal of Cell Biology | 1974 |
Infection and immunoglobulin concentrations in Chediak-Higashi mice
RJ Elin, JB Edelin, SM Wolff |
Infection and immunity | 1974 |
Molecular basis for functional disorders of phagocytes
RL Baehner |
The Journal of Pediatrics | 1974 |
Phagocytosis: The Normal Process and Its Clinically Significant Abnormalities
JA Winkelstein, RH Drachman |
Pediatric Clinics of North America | 1974 |
Diseases Which Simulate Allergy
RF Beers |
Medical Clinics of North America | 1974 |
Human Leucocytes and Infection
JA Raeburn |
Scottish Medical Journal | 1974 |
Neutrophil chemotaxis in systemic lupus erythematosus.
Clark RA, Kimball HR, Decker JL |
Annals of the rheumatic diseases | 1974 |
Disorders of neutrophil function. Defects in the early stages of the phagocytic process
PJ Edelson, DP Stites, S Gold, HH Fudenberg |
Clinical & Experimental Immunology | 1973 |
The Chediak-Higashi syndrome. Fine structure of giant inclusions in freeze-fractured neutrophils
JG White |
The American Journal of Pathology | 1973 |
Leukocyte movement—in vitro and in vivo correlates
ME Miller |
The Journal of Pediatrics | 1973 |
Granulocytopathies
PG Quie, HR Hill |
Disease-a-Month | 1973 |
Generation of chemotactic factors in guinea pig serum via activation of the classical and alternate complement pathways
RA Clark, MM Frank, HR Kimball |
Clinical Immunology and Immunopathology | 1973 |
Disorders of Host Defense Against Infection: Pathophysiologic and Diagnostic Considerations
RB Johnston, AR Lawton, MD Cooper |
Medical Clinics of North America | 1973 |
Problematik und klinische Bedeutung der Leukocyten-Funktionstestung
PA Miescher |
Klinische Wochenschrift | 1973 |
Abnormal Bactericidal, Metabolic, and Lysosomal Functions of Chediak-Higashi Syndrome Leukocytes
RK Root, AS Rosenthal, DJ Balestra |
Journal of Clinical Investigation | 1972 |
Disorders of Phagocyte Function
PG Quie |
Current Problems in Pediatrics | 1972 |
Protides of the Biological Fluids
PA Small, RH Waldman |
Protides of the Biological Fluids | 1969 |
The Inflammatory Process
R Macfarlane |
The Inflammatory Process | 1965 |
Hematology
JJ Shea, JJ Shea |
The Laryngoscope | 1949 |