Deposition and clearance of inhaled particles of iron oxide labeled with 198Au were studied in 19 normal subjects (10 nonsmokers and 9 smokers). For this purpose, monodisperse aerosols of particles with a 2 μ diameter were produced in a spinning disc atomizer. Thoracic counts and images with a scintillation camera were begun immediately after inhalation of the aerosol and continued for 6 hr.
Ruy V. Lourenço, Mary F. Klimek, Claudia J. Borowski
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Title and authors | Publication | Year |
---|---|---|
Advances in Smoking Related In Vitro Inhalation Toxicology: A Perspective Case of Challenges and Opportunities from Progresses in Lung-on-Chip Technologies
AV Singh, RS Maharjan, C Kromer, P Laux, A Luch, T Vats, V Chandrasekar, SP Dakua, BW Park |
Chemical Research in Toxicology | 2021 |
Prognostic and functional impact of perioperative LAMA/LABA inhaled therapy in patients with lung cancer and chronic obstructive pulmonary disease
Y Azuma, A Sano, T Sakai, S Koezuka, H Otsuka, N Tochigi, K Isobe, S Sakamoto, Y Takai, A Iyoda |
BMC Pulmonary Medicine | 2021 |
The “Polonium In Vivo” Study: Polonium-210 in Bronchial Lavages of Patients with Suspected Lung Cancer
V Zagà, MS Cattaruzza, P Martucci, R Pacifici, R Trisolini, P Bartolomei, R Giacobbe, M Patelli, D Paioli, M Esposito, V Fabbri, S Gallus, G Gorini |
Biomedicines | 2020 |
Lung Scintigraphy in the Assessment of Aerosol Deposition and Clearance
A Sanchez-Crespo |
Seminars in Nuclear Medicine | 2019 |
Mucociliary Clearance in Former Tobacco Smokers with Both Chronic Obstructive Pulmonary Disease and Chronic Bronchitis and the Effect of Roflumilast
BL Laube, KA Carson, G Sharpless, LM Paulin, NN Hansel |
Journal of Aerosol Medicine and Pulmonary Drug Delivery | 2019 |
Altered Viscosity of Nasal Secretions in Postnasal Drip
S Bucher, P Schmid-Grendelmeier, MB Soyka |
Chest | 2019 |
Quantitative Assessment of Mucociliary Clearance in Smokers with Mild-to-Moderate Chronic Obstructive Pulmonary Disease and Chronic Bronchitis from Planar Radionuclide Imaging Using the Change in Penetration Index
JS Fleming, J Conway, MJ Bennett, L Tossici-Bolt, M Guy, FX Blé, C McCrae, M Carlsson, E Bondesson |
Journal of Aerosol Medicine and Pulmonary Drug Delivery | 2019 |
Biomarkers of exposure to new and emerging tobacco delivery products
SF Schick, BC Blount, PJ rd, NA Saliba, JT Bernert, AE Hellani, P Jatlow, RS Pappas, L Wang, J Foulds, A Ghosh, SS Hecht, JC Gomez, JR Martin, C Mesaros, S Srivastava, GS Helen, R Tarran, PK Lorkiewicz, IA Blair, HL Kimmel, CM Doerschuk, NL Benowitz, A Bhatnagar |
American journal of physiology. Lung cellular and molecular physiology | 2017 |
The Effects of Electronic Cigarette (ECIG)-Generated Aerosol and Conventional Cigarette Smoke on the Mucociliary Transport Velocity (MTV) Using the Bullfrog (R. catesbiana) Palate Paradigm
DL Palazzolo, JM Nelson, EA Ely, AP Crow, J Distin, SC Kunigelis |
Frontiers in physiology | 2017 |
Cigarette smoke alters primary human bronchial epithelial cell differentiation at the air-liquid interface
AC Schamberger, CA Staab-Weijnitz, N Mise-Racek, O Eickelberg |
Scientific Reports | 2015 |
Handbook on the Toxicology of Metals
A Elder, GF Nordberg, M Kleinman |
Handbook on the Toxicology of Metals | 2015 |
FOXJ1 Prevents Cilia Growth Inhibition by Cigarette Smoke in Human Airway Epithelium In Vitro
A Brekman, MS Walters, AE Tilley, RG Crystal |
American journal of respiratory cell and molecular biology | 2014 |
Bacterial microbiome of lungs in COPD
MA Sze, JC Hogg, DD Sin |
International journal of chronic obstructive pulmonary disease | 2014 |
Comprehensive Physiology
SN Cheuvront, RW Kenefick |
Comprehensive Physiology | 2014 |
Interventions for preoperative smoking cessation
T Thomsen, N Villebro, AM Møller |
Cochrane Database of Systematic Reviews | 2014 |
The Influence of Dust Standards on the Prevalence and Severity of Coal Worker's Pneumoconiosis at Autopsy in the United States of America
V Vallyathan, DP Landsittel, EL Petsonk, J Kahn, JE Parker, KT Osiowy, FH Green |
Archives of pathology & laboratory medicine | 2011 |
Controlled Pulmonary Drug Delivery
HD Smyth, AJ Hickey |
2011 | |
Cochrane Database of Systematic Reviews: Reviews
N Shafiq, M Singh, S Kaur, P Khosla, S Malhotra, N Shafiq |
Cochrane Database of Systematic Reviews: Reviews | 2010 |
Pulmonary surfactant: an immunological perspective
ZC Chroneos, Z Sever-Chroneos, VL Shepherd |
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology | 2009 |
Molecular Characterization of Chronic Obstructive Pulmonary Disease-Related Non-Small Cell Lung Cancer Through Aberrant Methylation and Alterations of EGFR Signaling
M Suzuki, H Wada, M Yoshino, L Tian, H Shigematsu, H Suzuki, M Alaa, H Tamura, T Fujiwara, K Nagato, S Motohashi, Y Moriya, H Hoshino, S Yoshida, K Shibuya, K Hiroshima, Y Nakatani, I Yoshino |
Annals of Surgical Oncology | 2009 |
Impact of preoperative smoking status on postoperative complication rates and pulmonary function test results 1-year following pulmonary resection for non-small cell lung cancer
SS Groth, BA Whitson, MA Kuskowski, AM Holmstrom, JB Rubins, RF Kelly |
Lung Cancer | 2009 |
Smoking is associated with shortened airway cilia
PL Leopold, MJ O'Mahony, XJ Lian, AE Tilley, BG Harvey, RG Crystal |
PloS one | 2009 |
Role of Cilia, Mucus, and Airway Surface Liquid in Mucociliary Dysfunction: Lessons from Mouse Models
MA Mall |
Journal of Aerosol Medicine and Pulmonary Drug Delivery | 2008 |
Do airway clearance mechanisms influence the local and systemic effects of inhaled corticosteroids?
S Edsbäcker, P Wollmer, O Selroos, L Borgström, B Olsson, J Ingelf |
Pulmonary Pharmacology & Therapeutics | 2008 |
Use of mucolytics to enhance magnetic particle retention at a model airway surface
J Ally, W Roa, A Amirfazli |
Journal of Magnetism and Magnetic Materials | 2008 |
Use of Asthmatic Pulmonary Function Test Data to Predict Lung Deposition
RJ Robinson, RL Doolittle, JN DiFlorio |
Journal of Aerosol Medicine | 2007 |
Association of Chronic Obstructive Pulmonary Disease and Tumor Recurrence in Patients With Stage IA Lung Cancer After Complete Resection
Y Sekine, Y Yamada, M Chiyo, T Iwata, T Nakajima, K Yasufuku, M Suzuki, T Fujisawa |
The Annals of Thoracic Surgery | 2007 |
Factors Affecting Magnetic Retention of Particles in the Upper Airways: AnIn VitroandEx VivoStudy
J Ally, A Amirfazli, W Roa |
Journal of Aerosol Medicine | 2006 |
Smoking Cessation: Techniques and Potential Benefits
TM Ziedalski, SJ Ruoss |
Thoracic Surgery Clinics | 2005 |
Surgical Critical Care, Second Edition
J Berlauk |
Surgical Critical Care, Second Edition | 2005 |
Cochrane Database of Systematic Reviews
L Hooper, C Bartlett, GD Smith, S Ebrahim, L Hooper |
Cochrane Database of Systematic Reviews | 2004 |
The Cochrane Database of Systematic Reviews
L Hooper, C Bartlett, SG Davey, S Ebrahim |
The Cochrane Database of Systematic Reviews | 2003 |
Lung Biology in Health and Disease
N Zamel |
Lung Biology in Health and Disease: Experimental Models and Therapeutic Potential | 2003 |
Characterization of aerosol output from various nebulizer/compressor combinations
C Reisner, RK Katial, BB Bartelson, A Buchmeir, LJ Rosenwasser, HS Nelson |
Annals of Allergy Asthma & Immunology | 2001 |
Deposition and clearance: unique problems in the proximal airways and oral cavity in the young and elderly
GC Smaldone |
Respiration Physiology | 2001 |
Chronic Obstructive Pulmonary Disease
PJ Barnes |
New England Journal of Medicine | 2000 |
Air Pollution and Health
MC Madden, JE Gallagher |
Air Pollution and Health | 1999 |
Cellular and Biochemical Response of the Human Lung after Intrapulmonary Instillation of Ferric Oxide Particles
JC Lay, WD Bennett, AJ Ghio, PA Bromberg, DL Costa, CS Kim, HS Koren, RB Devlin |
American journal of respiratory cell and molecular biology | 1999 |
Managing Cough as a Defense Mechanism and as a Symptom
RS Irwin, LP Boulet, MM Cloutier, R Fuller, PM Gold, V Hoffstein, AJ Ing, FD McCool, P OByrne, RH Poe, UB Prakash, MR Pratter, BK Rubin |
Chest | 1998 |
A pathophysiological basis for informed preoperative smoking cessation counseling
W Akrawi, JL Benumof |
Journal of Cardiothoracic and Vascular Anesthesia | 1997 |
Treatment of Mucociliary Dysfunction
M Salathe, TG O'Riordan, A Wanner |
Chest | 1996 |
Effects of Oxygen Radicals on Ciliary Motility in Cultured Human Respiratory Epithelial Cells
M Yoshitsugu, S Matsunaga, Y Hanamure, M Rautiainen, K Ueno, T Miyanohara, S Furuta, K Fukuda, M Ohyama |
Auris, Nasus, Larynx | 1995 |
Concepts In Inhalation Toxicology
K Driscoll |
Concepts In Inhalation Toxicology | 1995 |
The Effect of a New Expectorant Drug on Mucus Transport in Chronic Bronchitis
A Santolicandro, S Baldi, C Giuntini |
Journal of Aerosol Medicine | 1995 |
Physiological Measurement
L Olseni, J Palmer, P Wollmer |
Physiological Measurement | 1994 |
Annexe E. clearance of particles from the respiratory tract
MR Bailey, M Roy |
Annals of the ICRP | 1994 |
Lung mucociliary clearance
J Mortensen, P Lange, J Nyboe, S Groth |
European Journal of Nuclear Medicine | 1994 |
Inhaled beta-2 agonists and steroids. Present state and future perspectives
A M Clauzel |
Clinical Reviews in Allergy | 1994 |
Bronchial mucus transport in chronic smokers and nonsmokers during general anesthesia
FX Konrad, T Schreiber, D Brecht-Kraus, M Georgieff |
Journal of Clinical Anesthesia | 1993 |
Regional Impairment of Mucociliary Clearance in Chronic Obstructive Pulmonary Disease
GC Smaldone, WM Foster, TG O'Riordan, MS Messina, RJ Perry, EG Langenback |
Chest | 1993 |
Perioperative smoking cessation and anesthesia: A review
TD Egan, KC Wong |
Journal of Clinical Anesthesia | 1992 |
Determinación del aclaramiento mucociliar nasal mediante el test de la sacarina en diversas enfermedades respiratorias
R Jolis, J Sauret, J Coromina, R Cornudella |
Archivos de Bronconeumología | 1992 |
Mineral Particles in the Human Bronchial Mucosa and Lung Parenchyma II. Cigarette Smokers Without Emphysema
A Churg, JL Wright, B Stevens, B Wiggs |
Experimental Lung Research | 1992 |
Impairment of Lung Mucociliary Clearance in Pigeon Fanciers
A Hasani, M Johnson, D Pavia, J Agnew, S Clarke |
Chest | 1992 |
Ineffectiveness of Cough for Enhancing Mucus Clearance in Asymptomatic Smokers
WD Bennett, WF Chapman, TR Gerrity |
Chest | 1992 |
Principles and Practice of Environmental Medicine
AB Tarcher |
1992 | |
International Review of Cytology
RA Miller |
International Review of Cytology | 1991 |
Ciliary activity and pollution
M Pedersen |
Lung | 1990 |
The Interaction of Inhaled Toxicants with Respiratory Tract Clearance Mechanisms
RB Schlesinger |
Critical Reviews in Toxicology | 1990 |
Intercomparison of Experimental Regional Aerosol Deposition Data
W Stahlhofen, G Rudolf, A James |
Journal of Aerosol Medicine | 1989 |
Theory (or model) of the joint influence of occupational exposure to carcinogenic dust and to cigarette smoke and occupational lung cancer
TD Sterling |
Experimental Pathology | 1989 |
Mucociliary Disorders: A Review
P Camner, B Mossberg |
Journal of Aerosol Medicine | 1988 |
The Effect of Inhaled Histamine on Human Tracheal Mucus Velocity and Bronchial Mucociliary Clearance
DJ Mussatto, CS Garrard, RV Lourenco |
American journal of respiratory and critical care medicine | 1988 |
Minireview: How Important is Mucociliary Clearance?
P Camner |
Experimental Lung Research | 1988 |
Editorial Is 24 Hour Lung Retention an Index of Alveolar Deposition?
WM Foster |
Journal of Aerosol Medicine | 1988 |
Spinning-disk generation and drying of monodisperse solid aerosols with output concentrations sufficient for single-breath inhalation studies
PR Byron, AJ Hickey |
Journal of Pharmaceutical Sciences | 1987 |
An isolated perfused rat lung preparation for the study of aerosolized drug deposition and absorption
PR Byron, SR Roberts, AR Clark |
Journal of Pharmaceutical Sciences | 1986 |
Prediction of drug residence times in regions of the human respiratory tract following aerosol inhalation
PR Byron |
Journal of Pharmaceutical Sciences | 1986 |
Mucociliary Clearance and Mucosal Surface Characteristics before and after Total Laryngectomy
M Maurizi, G Paludetti, G Almadori, F Ottaviani, T Todisco |
Acta Oto-laryngologica | 1986 |
Effects of airborne pollutants on mucociliary clearance
RK Wolff |
Environmental Health Perspectives | 1986 |
Interaction of asbestos, age, and cigarette smoking in producing radiographic evidence of diffuse pulmonary fibrosis
KH Kilburn, R Lilis, HA Anderson, A Miller, RH Warshaw |
The American Journal of Medicine | 1986 |
Oxidant-Mediated Ciliary Dysfunction
WJ Burman, WJ Martin |
Chest | 1986 |
Functional small airways defence in symptomless cigarette smokers
JE Agnew, MT Lopez-Vidriero, D Pavia, SW Clarke |
Thorax | 1986 |
Effect of cigarette smoking on nasal mucociliary clearance and ciliary beat frequency
PJ Stanley, R Wilson, MA Greenstone, L MacWilliam, PJ Cole |
Thorax | 1986 |
Pharmacodynamic Models of Selected Toxic Chemicals in Man
AD Smith, MC Thorne |
1986 | |
Infectious Diseases in the Female Patient
RP Galask, B Larsen |
1986 | |
Lung Response to Particulates with Emphasis on Asbestos and other Fibrous Dusts
KP Lee, JL Abraham |
Critical Reviews in Toxicology | 1985 |
Aerosol Penetration and Mucociliary Transport in the Healthy Human Lung
E Cotromanes, TR Gerrity, CS Garrard, RD Harshbarger, DB Yeates, DL Kendzierski, RV Lourenco |
Chest | 1985 |
Toxicology of Inhaled Materials
H Witschi, JD Brain |
1985 | |
The Effects of Acute Respiratory Virus Infection upon Tracheal Mucous Transport
CS Gerrard, RA Levandowski, TR Gerrity, DB Yeates, E Klein |
Archives of Environmental Health An International Journal | 1985 |
Particles causing lung disease
KH Kilburn |
Environmental Health Perspectives | 1984 |
Aerosols and the Lung
SW Clarke |
Aerosols and the Lung | 1984 |
Surgery for Morbid Obesity
JH Linner |
1984 | |
Continuous aerosol inhalation scintigraphy in the evaluation of early and advanced airways obstruction
T Weiss, P Dorow, R Felix |
European Journal of Nuclear Medicine | 1984 |
Possible effects on occupational lung cancer from smoking related changes in the mucus content of the lung
TD Sterling |
Journal of Chronic Diseases | 1983 |
The Effect of Aspirin on Lung Mucociliary Clearance
TR Gerrity, E Cotromanes, CS Garrard, DB Yeates, RV Lourenço |
New England Journal of Medicine | 1983 |
Rapidly Reversible Alterations of Pulmonary Epithelial Permeability Induced by Smoking
GR Mason, JM Uszler, RM Effros, E Reid |
Chest | 1983 |
Medical problems associated with tobacco smoking
MD Clee, RA Clark |
Pharmacology & Therapeutics | 1982 |
Inhaled Particles V
HN MACfARLAND, W Coate, D Disbennett, L Ackerman |
Inhaled Particles V | 1982 |
Anaesthesiologie, Intensivmedizin und Reanimatologie
H Benzer, R Frey, W Hügin, O Mayrhofer |
1982 | |
Particle deposition and clearance in the bronchial tree
DB Yeates, TR Gerrity, CS Garrard |
Annals of Biomedical Engineering | 1981 |
Measurement of mucociliary clearance in smokers and nonsmokers using a bronchoscopic video-technical method
H Toomes, I Vogt-Moykopf, WD Heller, H Ostertag |
Lung | 1981 |
Response of Human Mucociliary Clearance to Acute Alcohol Administration
PC Venizelos, TR Gerrity, DB Yeates |
Archives of Environmental Health An International Journal | 1981 |
Analysis of Aerosol Deposition in the Healthy Human Lung
CS Garrard, TR Gerrity, JF Schreiner, DB Yeates |
Archives of Environmental Health An International Journal | 1981 |
Possible risks to human lungs from magnetometric dust clearance experiments
TD Sterling |
Journal of Applied Physics | 1981 |
Methods in Clinical Pharmacology—Respiratory System
JB Howell, AE Tattersfield |
1981 | |
INCREASED ALVEOLAR EPITHELIAL PERMEABILITY IN CIGARETTE SMOKERS
JG Jones, P Lawler, JC Crawley, BD Minty, G Hulands, N Veall |
The Lancet | 1980 |
Deposition, retention, and clearance of inhaled particles
M Lippmann, DB Yeates, RE Albert |
British journal of industrial medicine | 1980 |
Lung mucus production and mucociliary clearance: methods of assessment
SW Clarke, D Pavia |
British Journal of Clinical Pharmacology | 1980 |
Mucociliary Clearance of Deposited Particles from the Human Lung: Intra- and Inter-Subject Reproductivity, Total and Regional Lung Clearance, and Model Comparisons
DD Wilkey, P Lee, FJ Hass, TR Gerrity, DB Yeates, RV Lourenco |
Archives of Environmental Health An International Journal | 1980 |
Mucociliary Clearance of Deposited Particles from the Human Lung: Intra- and Inter-Subject Reproductivity, Total and Regional Lung Clearance, and Model Comparions
DD Wilkey, PS Lee, FJ Hass, TR Gerrity, DB Yeates, RV Lourenco |
Archives of Environmental Health An International Journal | 1980 |
A simplified method of monitoring muco-ciliary transport
DJ Dowsett |
British Journal of Radiology | 1980 |
A, Model for Tracheobronchial Clearance of Inhaled Particles in Man and a Comparison with Data
PS Lee, TR Gerrity, FJ Hass, RV Lourenco |
IEEE Transactions on Biomedical Engineering | 1979 |
The Effect of Enzyme-Induced Pulmonary Emphysema in Syrian Hamsters on the Deposition and Long-Term Retention of Inhaled Particles
FF Hahn, CH Hobbs |
Archives of Environmental Health An International Journal | 1979 |
Effect of Tobacco Smoke on the Metabolism of Rat Lung
M Hamosh, Y Shechter, P Hamosh |
Archives of Environmental Health An International Journal | 1979 |
The Retention of Uranium Dioxide Particles in the Trachea of the Rat
G Patrick |
International Journal of Radiation Biology and Related Studies in Physics, Chemistry and Medicine | 1979 |
Regional deposition of 2.5–7.5 μm diameter inhaled particles in healthy male non-smokers
N Foord, A Black, M Walsh |
Journal of Aerosol Science | 1978 |
Effects of atropine and methacholine on deposition and clearance of inhaled particles in the donkey
J Berger, RE Albert, K Sanborn, M Lippmann |
Journal of Toxicology and Environmental Health | 1978 |
The Effects of Smoking on the Lungs
AJ Woolcock, N Berend |
Australian and New Zealand Journal of Medicine | 1977 |
Apparatus for the administration by inhalation of radioactive particles to human subjects for studies of deposition and clearance
M Walsh, A Black, N Foord |
Journal of Aerosol Science | 1977 |
Familial prevalence of chronic obstructive pulmonary disease in a matched pair study
F Kueppers, RD Miller, H Gordon, NG Hepper, K Offord |
The American Journal of Medicine | 1977 |
Measurement of Mucociliary Transport Velocity in the Intact Mucosa
SK Chopra, GV Taplin, DH Simmons, D Elam |
Chest | 1977 |
Early Detection of Chronic Obstructive Pulmonary Disease Using Radionuclide Lung-Imaging Procedures
GV Taplin, DP Tashkin, SK Chopra, OE Anselmi, D Elam, B Calvarese, A Coulson, R Detels, SN Rokaw |
Chest | 1977 |
Lung Defense Mechanisms
M Newhouse, J Sanchis, J Bienenstock |
New England Journal of Medicine | 1976 |
Fine Particles
OG Raabe |
Fine Particles | 1976 |
Effect of Oxygen in Graded Concentrations upon Tracheal Mucous Velocity
MA Sackner, JA Hirsch, S Epstein, AM Rywlin |
Chest | 1976 |
A simple laser alignment system for spinning disk aerosol generator
PS Lee, FJ Hass, RV LourenÇo |
Journal of Aerosol Science | 1975 |
Tracheobronchial Particle Deposition and Clearance: A Study of the Effects of Cigarette Smoking in Monozygotic Twins
DE Bohning, RE Albert, M Lippmann, WM Foster |
Archives of Environmental Health An International Journal | 1975 |
Radioaerosol Lung Imaging in Chronic Obstructive Pulmonary Disease
L Ramanna, DP Tashkin, GV Taplin, D Elam, R Detels, A Coulson, SN Rokaw |
Chest | 1975 |
Cellular Effects of Cigarette Smoke on Hamster Airways
KH Kilburn, WN McKenzie, RJ Thurston |
Chest | 1975 |
Leukocyte Recruitment to Airways by Cigarette Smoke and Particle Phase in Contrast to Cytotoxicity of Vapor
KH Kilburn, W McKenzie |
Science | 1975 |
Production of 99Tcm labelled albumin microspheres for lung clearance studies and inhalation scanning
DB Yeates, A Warbick, N Aspin |
The International Journal of Applied Radiation and Isotopes | 1974 |
A preliminary study of the effect of guaiphenesin on mucociliary clearance from the human lung
ML Thomson, D Pavia, MW McNicol |
Thorax | 1973 |
Tracheal Mucous Velocity in Beagles After Chronic Exposure to Cigarette Smoke
A Wanner, JA Hirsch, DE Greeneltch, EW Swenson, T Fore |
Archives of Environmental Health An International Journal | 1973 |
Withdrawal of Cigarette Smoking
P Camner, K Philipson, T Arvidsson |
Archives of Environmental Health An International Journal | 1973 |
Die Inhalationsbronchographie mit Tantalstaub und ihre Probleme
E Kammler, W Weller, WT Ulmer, E Bruckmann |
Pneumonologie Pneumonology | 1972 |
Tracheobronchial Clearance in Smoking-Discordant Twins
P Camner, K Philipson |
Archives of Environmental Health An International Journal | 1972 |
Die Inhalationsbronchographie mit Tantalstaub und ihre Probleme
E Kammler, W Weller, WT Ulmer, E Bruckmann |
Lung | 1972 |