Cholate metabolism was studied in fetal dogs 1 wk before term and was compared with cholate metabolism in adult dogs. Tracer amounts of sodium cholate-14C were administered to the fetus in utero by intravenous infusion over 6 hr. Fetal plasma disappearance, biliary excretion, tissue distribution, and placental transfer of cholate were measured over 10 hr.
Authors
B. T. Jackson, R. A. Smallwood, G. J. Piasecki, A. S. Brown, H. F. J. Rauschecker, R. Lester
