Responses of coronary vessels to adrenergic stimuli

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Abstract

Coronary responses to adrenergic stimuli were determined in the intact beating heart before and after administration of practolol, 4-(2-hydroxy-3-isopropylaminoproproxy) acetanilide, which in low doses blocks myocardial but not vascular beta receptors. The left circumflex coronary artery of dogs was perfused with arterial blood at constant flow, and coronary perfusion pressure was measured.

Authors

Donald R. McRaven, Allyn L. Mark, Francois M. Abboud, Howard E. Mayer