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Usage Information

Decreased 19S antibody response to bacterial antigens in systemic lupus erythematosus
John Baum, Morris Ziff
John Baum, Morris Ziff
Published April 1, 1969
Citation Information: J Clin Invest. 1969;48(4):758-767. https://doi.org/10.1172/JCI106033.
View: Text | PDF
Research Article

Decreased 19S antibody response to bacterial antigens in systemic lupus erythematosus

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Abstract

The antibody response to immunization with Brucella and the levels of natural antibody to Escherichia coli and Shigella were compared in patients with systemic lupus erythematosus and control groups. After Brucella immunization, SLE patients showed a significantly lower antibody response in whole serum and in the macroglobulin antibody fraction separated by sucrose density gradient centrifugation.

Authors

John Baum, Morris Ziff

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