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Citations to this article

Growth hormone secretion during sleep
Y. Takahashi, … , D. M. Kipnis, W. H. Daughaday
Y. Takahashi, … , D. M. Kipnis, W. H. Daughaday
Published September 1, 1968
Citation Information: J Clin Invest. 1968;47(9):2079-2090. https://doi.org/10.1172/JCI105893.
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Growth hormone secretion during sleep

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Abstract

Plasma growth hormone (GH), insulin, cortisol, and glucose were measured during sleep on 38 nights in eight young adults. Blood was drawn from an indwelling catheter at 30-min intervals; EEG and electrooculogram were recorded throughout the night. In seven subjects, a plasma GH peak (13-72 mμg/ml) lasting 1.5-3.5 hr appeared with the onset of deep sleep. Smaller GH peaks (6-14 mμg/ml) occasionally appeared during subsequent deep sleep phases. Peak GH secretion was delayed if the onset of sleep was delayed. Subjects who were awakened for 2-3 hr and allowed to return to sleep exhibited another peak of GH secretion (14-46 mμg/ml). Peak GH secretion was not correlated with changes in plasma glucose, insulin, and cortisol. The effects of 6-CNS-active drugs on sleep-related GH secretion were investigated. Imipramine (50 mg) completely abolished GH peaks in two of four subjects, whereas chlorpromazine (30 mg), phenobarbital (97 mg), diphenylhydantoin (90 mg), chlordiazepoxide (20 mg), and isocarboxazid (30 mg) did not inhibit GH peaks. Altered hypothalamic activity associated with initiation of sleep results in a major peak of growth hormone secretion unrelated to hypoglycemia or changes in cortisol and insulin secretion.

Authors

Y. Takahashi, D. M. Kipnis, W. H. Daughaday

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Comprehensive Physiology 2010
Contribution of sedative-hypnotic agents to delirium via modulation of the sleep pathway
RD Sanders, M Maze
Canadian journal of anaesthesia = Journal canadien d'anesthésie 2010
Circadian Timekeeping and Multiple Timescale Neuroendocrine Rhythms
X Bonnefont
Journal of Neuroendocrinology 2010
Sleep and physical growth in infants during the first 6 months
L Tikotzky, GD Marcas, J Har-Toov, S Dollberg, Y Bar-Haim, A Sadeh
Journal of Sleep Research 2010
Vitamins & Hormones
KJ Hare, FK Knop
Vitamins & Hormones 2010
Identification of a Neural Circuit that Underlies the Effects of Octopamine on Sleep:Wake Behavior
A Crocker, M Shahidullah, IB Levitan, A Sehgal
Neuron 2010
The Effect of Prior Endurance Training on Nap Sleep Patterns
DD J., GK S., CC Moi
INT J SPORT PHYSIOL 2010
Dose-dependent relationship between severity of pediatric obesity and blunting of the growth hormone response to exercise
SR Oliver, JS Rosa, TD Minh, AM Pontello, RL Flores, M Barnett, PR Galassetti
Journal of applied physiology 2010
Growth hormone-releasing hormone activates sleep regulatory neurons of the rat preoptic hypothalamus
Z Peterfi, D McGinty, E Sarai, R Szymusiak
American Journal of Physiology - Regulatory, Integrative and Comparative Physiology 2010
Pulmonary surfactant: an immunological perspective
ZC Chroneos, Z Sever-Chroneos, VL Shepherd
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2009
Growth hormone and protein metabolism
N Moller, MH Vendelbo, U Kampmann, B Christensen, M Madsen, H Norrelund, JO Jorgensen
Clinical Nutrition 2009
Measurement of internal body time by blood metabolomics
Y Minami, T Kasukawa, Y Kakazu, M Iigo, M Sugimoto, S Ikeda, A Yasui, GT van der Horst, T Soga, HR Ueda
Proceedings of the National Academy of Sciences 2009
BIOLOGICAL TIMEKEEPING
MU Gillette, SM Abbott
Sleep Medicine Clinics 2009
Detection of doping with recombinant human growth hormone
C He, M Wu
Bioanalysis 2009
Physiologic Changes in Sleep
S Chokroverty
Sleep Disorders Medicine 2009
An Overview of Normal Sleep
S Chokroverty
Sleep Disorders Medicine 2009
Injecting human growth hormone as a performance-enhancing drug—perspectives from the United Kingdom
M Evans-Brown, J McVeigh
Journal of Substance Use 2009
The anterolateral projections of the medial basal hypothalamus affect sleep
Z Peterfi, GB Makara, F Obál, JM Krueger
American Journal of Physiology - Regulatory, Integrative and Comparative Physiology 2009
An Evaluation of the Neuroendocrine Response to Sleep in Pediatric Burn Patients
MM Gottschlich, J Khoury, GD Warden, RJ Kagan
JPEN. Journal of parenteral and enteral nutrition 2009
Effects of Growth Hormone on Glucose, Lipid, and Protein Metabolism in Human Subjects
N Møller, JO Jørgensen
Endocrine reviews 2009
Physiological and pharmacological basis for the ergogenic effects of growth hormone in elite sports
C Ehrnborg, T Rosén
Asian Journal of Andrology 2008
Growth hormone, IGF-I and insulin and their abuse in sport
RI Holt, PH Sönksen
British Journal of Pharmacology 2008
Sleep Disorders: Diagnosis and Therapeutics
F García-García, R Drucker-Colín
Sleep Disorders: Diagnosis and Therapeutics 2008
The influence of sleep and sleep loss upon food intake and metabolism
CA Crispim, I Zalcman, M Dáttilo, HG Padilha, B Edwards, J Waterhouse, S Tufik, MT de Mello
Nutrition Research Reviews 2007
The Effects of Gammahydroxybutyrate on Hypermetabolism and Wound Healing in a Rat Model of Large Thermal Injury
KD Murphy, MW Rose, DL Chinkes, WJ Meyer, DN Herndon, HK Hawkins, AP Sanford
The Journal of Trauma: Injury, Infection, and Critical Care 2007
Neuropeptides as possible targets in sleep disorders
S Nishino, N Fujiki
Expert Opinion on Therapeutic Targets 2007
Age-related Sleep Alterations: Implications for Endocrine Function
G Copinschi, A Caufriez
Sleep Medicine Clinics 2007
Handbook of Neurochemistry and Molecular Neurobiology
VH Routh, JJ McArdle, NM Sanders, Z Song, R Wang
Handbook of Neurochemistry and Molecular Neurobiology 2007
Complex Rhythmicity of Growth Hormone Secretion in Humans
S Surya, K Symons, E Rothman, AL Barkan
Pituitary 2006
Sleep in spontaneous dwarf rats
Z Peterfi, F Obal, P Taishi, J Gardi, B Kacsoh, T Unterman, JM Krueger
Brain Research 2006
A motilin agonist, erythromycin, decreases circulating growth hormone levels in normal subjects but not in diabetic subjects
N Ueno, M Uemoto, Y Komatsu, Y Sato, A Inui
Journal of Diabetes and its Complications 2006
Long-term GH treatment of GH-deficient adults: Comparison between one and two daily injections
C Höybye, M Rudling
Journal of Endocrinological Investigation 2006
The somatotropic axis in sleep and thermoregulation: A tribute to Ferenc Obál, Jr. (1948–2004)
P Alföldi, L Kapás, E Szentirmai, P Taishi, J Gardi, Z Peterfi, B Kacsóh, JM Krueger
Journal of Thermal Biology 2006
Comparison of the effects of a 24‐hour nicotine patch and a 16‐hour nicotine patch on smoking urges and sleep
HJ Aubin, R Luthringer, A Demazières, C Dupont, G Lagrue
Nicotine & Tobacco Research 2006
Sleep and Sleep Disorders
M Lader, DP Cardinali, SR Pandi-Perumal
2006
Minireview: Gender-specific sleep regulation*
M KIMURA
Sleep and Biological Rhythms 2005
How Pain and Analgesics Disturb Sleep
SH Onen, F Onen, P Courpron, C Dubray
The Clinical Journal of Pain 2005
Endocrine Physiology
EV Cauter
Principles and Practice of Sleep Medicine 2005
International Review of Neurobiology
ZT Bloomgarden
International review of neurobiology 2005
The Somatotrophic Axis in Brain Function
HJ Schneider, GK Stalla
The Somatotrophic Axis in Brain Function 2005
Handbook of the Biology of Aging
PM Wise
Handbook of the Biology of Aging 2005
Night sleep EEG and daytime sleep propensity in adult hypopituitary patients with growth hormone deficiency before and after six months of growth hormone replacement
HJ Schneider, H Oertel, H Murck, T Pollmächer, GK Stalla, A Steiger
Psychoneuroendocrinology 2005
Neuroendocrine Correlates of Sleep/Wakefulness
DP Cardinali, SR Pandi-Perumal
2005
GHRH and sleep
F Obal, JM Krueger
Sleep Medicine Reviews 2004
Clinical pharmacological aspects of growth hormone administration
T Laursen
Growth Hormone & IGF Research 2004
Lung Biology in Health and Disease: Basic Science, Physiology and Behavior
H Gaudreau, J Carrier, BM Tchiteya
Lung Biology in Health and Disease: Experimental Models and Therapeutic Potential 2004
EFFECT OF MULTI-FUNCTIONAL FABRIC ON SLEEP STAGES AND GROWTH HORMONE LEVELS DURING SLEEP
MS Lee, J Song, HJ Kim, KW Park, SR Moon
International Journal of Neuroscience 2004
Reductions in circulating anabolic hormones induced by sustained sleep deprivation in rats
CA Everson, WR Crowley
American journal of physiology. Endocrinology and metabolism 2004
Sleep enhances nocturnal plasma ghrelin levels in healthy subjects
A Dzaja, MA Dalal, H Himmerich, M Uhr, T Pollmächer, A Schuld
American journal of physiology. Endocrinology and metabolism 2004
Sleep
M Billiard
Sleep 2003
Role of Hypolipidemic Drug Clofibrate in Altering Iron Regulatory Proteins IRP1 and IRP2 Activities and Hepatic Iron Metabolism in Rats Fed a Low-Iron Diet
HL Huang, NS Shaw
Toxicology and Applied Pharmacology 2002
Sleep Disturbance After Burn Injury
SA Boeve, LA Aaron, SP Martin-Herz, A Peterson, V Cain, DM Heimbach, DR Patterson
Journal of Burn Care & Rehabilitation 2002
Advances in Cell Aging and Gerontology
T Fülöp, K Hirokawa, G Dupuis, A Larbi, G Pawelec
Advances in Cell Aging and Gerontology 2002
Sleep-wake mechanisms and drug discovery: sleep EEG as a tool for the development of CNS-acting drugs
L Staner
Dialogues in clinical neuroscience 2002
Hormones and Breathing
T Saaresranta, O Polo
Chest 2002
Sleep of transgenic mice producing excess rat growth hormone
I Hajdu, F Obal, J Fang, JM Krueger, CD Rollo
American Journal of Physiology - Regulatory, Integrative and Comparative Physiology 2002
Quality of sleep and its daily relationship to pain intensity in hospitalized adult burn patients
I Raymond, TA Nielsen, G Lavigne, C Manzini, M Choinière
PAIN 2001
Sleep, sleepiness, sleep disorders and alcohol use and abuse
T Roehrs, T Roth
Sleep Medicine Reviews 2001
Hormonal responses to exercise after partial sleep deprivation and after a hypnotic drug-induced sleep
F Mougin, H Bourdin, ML Simon-Rigaud, UN Nhu, JP Kantelip, D Davenne
Journal of Sports Sciences 2001
Clinical implications of pulsatile hormone signals
BP Hauffa
Growth Hormone & IGF Research 2001
Functional Neurobiology of Aging
PL Thornton, WE Sonntag
Functional Neurobiology of Aging 2001
Hormone de croissance et sport
M Saugy
Revue Française des Laboratoires 2001
Handbook of Behavioral Neurobiology
JS Takahashi, FW Turek, RY Moore
2001
Sleep, sleepiness, and alcohol use
T Roehrs, T Roth
Alcohol research & health : the journal of the National Institute on Alcohol Abuse and Alcoholism 2001
Decline of life’s energy theory of ageing 1. Revitalisation of energy metabolism and ageing mitochondria
GF Grant, T Parr
Expert Opinion on Therapeutic Patents 2000
Growth hormone abuse
C Ehrnborg, BÅ Bengtsson, T Rosén
Best Practice & Research Clinical Endocrinology & Metabolism 2000
Slow-wave sleep and waking cognitive performance II
JD Edinger, DM Glenn, LA Bastian, GR Marsh
Physiology & Behavior 2000
Sleep stage-related changes in sympathetic sudomotor and vasomotor skin responses in man
R Liguori, V Donadio, E Foschini, VD Stasi, G Plazzi, E Lugaresi, P Montagna
Clinical Neurophysiology 2000
Adaptation of the 24-h growth hormone profile to a state of sleep debt
K Spiegel, R Leproult, EF Colecchia, M L'Hermite-Balériaux, Z Nie, G Copinschi, EV Cauter
American Journal of Physiology - Regulatory, Integrative and Comparative Physiology 2000
The evolution of sleep: a reconsideration of the development of the quiet sleep/active sleep cycle
L Taylor, A Vana, L Givon
Medical Hypotheses 2000
The Severity of Chronic Heart Failure due to Coronary Artery Disease Predicts the Endocrine Effects of Short- Term Growth Hormone Administration1
KJ Osterziel, WF Blum, O Strohm, R Dietz
The Journal of clinical endocrinology and metabolism 2000
Suppression of the nocturnal rise in growth hormone reduces subsequent lipolysis in subcutaneous adipose tissue
Samra, Clark, Humphreys, Macdonald, Bannister, Matthews, Frayn
European Journal of Clinical Investigation 1999
Orexin A activates locus coeruleus cell firing and increases arousal in the rat
JJ Hagan, RA Leslie, S Patel, ML Evans, TA Wattam, S Holmes, CD Benham, SG Taylor, C Routledge, P Hemmati, RP Munton, TE Ashmeade, AS Shah, JP Hatcher, PD Hatcher, DN Jones, MI Smith, DC Piper, AJ Hunter, RA Porter, N Upton
Proceedings of the National Academy of Sciences 1999
Slow-Wave Sleep and Waking Cognitive Performance Among Older Adults With and Without Insomnia Complaints
MC Crenshaw, JD Edinger
Physiology & Behavior 1999
A review of normal sleep and its disturbances in Parkinson’s disease
PK Pal, S Calne, A Samii, JA Fleming
Parkinsonism & Related Disorders 1999
Neuroendocrinology of the humangrowth hormone-insulin-like growth factor I axis during ageing
E Arvat, R Giordano, L Gianotti, F Broglio, F Camanni, E Ghigo
Growth Hormone & IGF Research 1999
Diurnal variations and sleep deprivation-induced changes in rat hypothalamic GHRH and somatostatin contents
J Gardi, F Obál, J Fang, J Zhang, JM Krueger
American Journal of Physiology - Regulatory, Integrative and Comparative Physiology 1999
Development and Evaluation of a Direct Immunofluorimetric Assay for Urinary Growth Hormone
MG McConway, KA Smith, GH Beastall
Annals of Clinical Biochemistry 1999
Ultradian rhythms in pituitary and adrenal hormones: their relations to sleep
C Gronfier, G Brandenberger
Sleep Medicine Reviews 1998
Effect of modafinil on plasma melatonin, cortisol and growth hormone rhythms, rectal temperature and performance in healthy subjects during a 36 h sleep deprivation
J Brun, G Chamba, Y Khalfallah, P Girard, I Boissy, H Bastuji, G Sassolas, B Claustrat
Journal of Sleep Research 1998
Growth hormone secretion during sleep in male depressed patients
PN Sakkas, CR Soldatos, JD Bergiannaki, TJ Paparrigopoulos, CN Stefanis
Progress in Neuro-Psychopharmacology and Biological Psychiatry 1998
Intense Sympathetic Nerve Activity in Adults with Hypopituitarism and Untreated Growth Hormone Deficiency 1
YB Sverrisdóttir, M Elam, H Herlitz, BÅ Bengtsson, G Johannsson
The Journal of clinical endocrinology and metabolism 1998
Evidence against a role for the growth hormone-releasing peptide axis in human slow-wave sleep regulation
R Moreno-Reyes, M Kerkhofs, M LHermite-Balériaux, MO Thorner, EV Cauter, G Copinschi
American journal of physiology. Endocrinology and metabolism 1998
Sleep deprivation increases rat hypothalamic growth hormone-releasing hormone mRNA
J Zhang, Z Chen, P Taishi, F Obál, J Fang, JM Krueger
American Journal of Physiology - Regulatory, Integrative and Comparative Physiology 1998
Peptidomimetic Growth Hormone Secretagogues. Design Considerations and Therapeutic Potential
RP Nargund, AA Patchett, MA Bach, MG Murphy, RG Smith
Journal of Medicinal Chemistry 1998
Simultaneous stimulation of slow-wave sleep and growth hormone secretion by gamma-hydroxybutyrate in normal young Men
EV Cauter, L Plat, MB Scharf, R Leproult, S Cespedes, M L'Hermite-Balériaux, G Copinschi
Journal of Clinical Investigation 1997
Lack of Effect of Sleep on Energy Expenditure and Physiologic Measures in Critically Ill Burn Patients
MM Gottschlich, M Jenkins, T Mayes, J Khoury, R Kagan, GD Warden
Journal of the American Dietetic Association 1997
Behavioural rhythmicity in transgenic growth hormone mice: trade-offs, energetics, and sleep–wake cycles
CD Rollo, J Foss, E Lachmansingh, R Singh
Canadian Journal of Zoology 1997
Growth Hormone Secretion in Night Workers
L Weibel, M Follenius, K Spiegel, C Gronfier, G Brandenberger
Chronobiology International 1997
Reduced Efficacy of Growth Hormone-Releasing Hormone in Modulating Sleep Endocrine Activity in the Elderly
J Guldner, T Schier, E Friess, M Colla, F Holsboer, A Steiger
Neurobiology of Aging 1997
Specific abnormalities in a visual motor psychological test in short children with abnormal growth hormone secretion
A Andronikof-Sanglade, A Fjellestad-Paulsen, S Ricard-Malivoir, D Evain-Brion
Acta Paediatrica 1997
Role of Gorwth Hormone in Ovarian Physiology and Onest of Puberty
FI Sharara, LC Giudice
Journal of the Society for Gynecologic Investigation 1997
Nocturnal rise of leptin in lean, obese, and non-insulin-dependent diabetes mellitus subjects
MK Sinha, JP Ohannesian, ML Heiman, A Kriauciunas, TW Stephens, S Magosin, C Marco, JF Caro
Journal of Clinical Investigation 1996
Insulin-like growth factor-I in man enhances lipid mobilization and oxidation induced by a growth hormone pulse
TL Bianda, MA Hussain, A Keller, Y Glatz, O Schmitz, JS Christiansen, KG Alberti, ER Froesch
Diabetologia 1996
THE REGULATION OF GROWTH HORMONE SECRETION
L Cuttler
Endocrinology & Metabolism Clinics of North America 1996
Pulsatile nature of growth hormone levels in critically ill trauma victims
JS Samra, DR Matthews, LK Summers
Surgery 1996
Nocturnal Monitoring of Growth Hormone, Insulin, C-Peptide, and Glucose in Patients With Acromegaly
JS Tsai, LL Zorrilla, KK Jacob, S Rosenberg, DL Marcus
The American Journal of the Medical Sciences 1996
Two Types of Growth Hormone Rhythm in Boys with Constitutional Short Stature
R Keret, IE Ashkenazi, M Wasserman, B Bauman, A Pertzelan, A Ticher, Z Laron
Journal of Pediatric Endocrinology and Metabolism 1996
SLEEP AND NEUROMUSCULAR DISORDERS
A Culebras
Neurologic Clinics 1996
Methods in Neurosciences
V Rybin, HM Han, SF Steinberg
Methods in Neurosciences 1996
Physiology of growth hormone secretion during sleep
EV Cauter, L Plat
The Journal of Pediatrics 1996
Évaluation de l'apport alimentaire en vitamine A chez l'enfant avec et sans retard statural
MO Greneche, L François, A Fjellestad-Paulsen, D Evain-Brion
Archives de Pédiatrie 1996
Effects of systemic GHRH on sleep in intact and hypophysectomized rats
F Obal, R Floyd, L Kapas, B Bodosi, JM Krueger
American journal of physiology. Endocrinology and metabolism 1996
Net flux of amino acids over the hind limbs of growing pigs in relation to feeding and time of day
K Malmlöf, J örberg, Z Cortova, S Björkgren
Journal of Animal Physiology and Animal Nutrition 1995
The 24-hour Rhythms in Plasma Growth Hormone, Prolactin and Thyroid Stimulating Hormone: Effect of Sleep Deprivation
M Sadamatsu, N Kato, H Iida, S Takahashi, K Sakaue, K Takahashi, S Hashida, E Ishikawa
Journal of Neuroendocrinology 1995
Growth hormone secretion timing in depression: Clinical outcome comparisons
B Franz, DJ Kupfer, JM Miewald, DB Jarrett, VJ Grochocinski
Biological Psychiatry 1995
Interaction between sleep and growth hormone
C Åström
Acta Neurologica Scandinavica 1995
The hypothalamic-pituitary-adrenocortical system and sleep in man
E Friess, K Wiedemann, A Steiger, F Holsboer
Advances in Neuroimmunology 1995
Food intake after amygdaloid lesion in rats
R Crovetti, F Lucchetti, M Mancia, M Mariotti, M Porrini, P Spinnler, G Testolin
Nutrition Research 1995
The Pharmacology of Sleep
A Kales
1995
Late Sequelae in Oncology
J Dunst, R Sauer
1995
Diminished brain glucose metabolism is a significant determinant for falling rates of systemic glucose utilization during sleep in normal humans
PJ Boyle, JC Scott, AJ Krentz, RJ Nagy, E Comstock, C Hoffman
Journal of Clinical Investigation 1994
Metabolic effects of growth hormone administered subcutaneously once or twice daily to growth hormone deficient adults
T Laursen, JO Jergensen, JS Chrlstiansen
Clinical Endocrinology 1994
Sleep-related growth hormone secretion is persistently suppressed in women with recurrent depression: A preliminary longitudinal analysis
DB Jarrett, DJ Kupfer, JM Miewald, VJ Grochocinski, B Franz
Journal of Psychiatric Research 1994
Effects of pulsatile cortisol infusion on sleep-EEG and nocturnal growth hormone release in healthy men
E Friess, U BARDELEBEN, K Wiedemann, CJ Lauer, F Holsboer
Journal of Sleep Research 1994
Nonphotic stimuli alter a day-night rhythm of allograft rejection in gulf killifish
NJ Nevid, AH Meier
Developmental & Comparative Immunology 1994
Time Dependency of Pyridostigmine-Induced Growth Hormone Response
JH Thakore, I Coffey, TG Dinan
Journal of Basic and Clinical Physiology and Pharmacology 1994
Current methods for the measurement of growth hormone in urine
P Hourd, R Edwards
Clinical Endocrinology 1994
Advances in Pharmacology
B Drenger, Y Ginosar, Y Gozal
Advances in Pharmacology 1994
Sleep Disorders Medicine
S Chokroverty
Sleep Disorders Medicine 1994
Diseases of the Pituitary
SL Asa
Neurosurgery Clinics of North America 1994
Advances in medical therapy for pituitary disease: treating patients with growth hormone excess and deficiency
D Jenkins, PM Stewart
Journal of Clinical Pharmacy and Therapeutics 1993
Evaluation of pulsatile patterns of growth hormone release in humans: A brief review
ML Hartman, A Iranmanesh, MO Thorner, JD Veldhuis
American Journal of Human Biology 1993
Role of central nervous system and behaviour in the immune response
AJ Husband
Vaccine 1993
Influence of partial sleep deprivation on the secretion of thyrotropin, thyroid hormones, growth hormone, prolactin, luteinizing hormone, follicle stimulating hormone, and estradiol in healthy young women
A Baumgartner, M Dietzel, B Saletu, R Wolf, A Campos-Barros, KJ Gräf, I Kürten, U Mannsmann
Psychiatry Research 1993
Profiles of spontaneous 24-hour and stimulated growth hormone secretion in male patients with endogenous depression
U Voderholzer, G Laakmann, R Wittmann, C Daffner-Bujia, A Hinz, C Haag, T Baghai
Psychiatry Research 1993
Biological rhythms in patients with lissencephaly (agyria-pachygyria)
K Mori, T Hashimoto, M Tayama, K Fukuda, S Endo, Y Kuroda
Brain and Development 1993
Sleep-promoting effects of growth hormone-releasing hormone in normal men
M Kerkhofs, EV Cauter, AV Onderbergen, A Caufriez, MO Thorner, G Copinschi
American journal of physiology. Endocrinology and metabolism 1993
Dependency of growth hormone (GH) stimulation following releasing hormones on the spontaneous 24-hour GH secretion in healthy male and female subjects
U Voderholzer, G Laakmann, A Hinz, C Daffner, C Haag, HP Hofmann, B Börschel
Psychoneuroendocrinology 1993
Evaluation of Growth Hormone Secretion and Treatment
P Tapanainen, M Knip
Annals of Medicine 1992
Urinary Growth Hormone: Its Relation to Growth and Development (The Wessex Growth Study)
H Bullen, L Voss, Τ Sleeman, T Wilkin
Journal of Pediatric Endocrinology and Metabolism 1992
Regulation of Sleep and Growth Hormone in Adolescent Depression
RE Dahl, ND Ryan, DE Williamson, PJ Ambrosini, H Rabinovich, H Novacenko, B Nelson, J Puig-Antich
Journal of the American Academy of Child & Adolescent Psychiatry 1992
Sleep disturbance in children with growth hormone deficiency
M Hayashi, M Shimohira, S Saisho, K Shimozawa, Y Iwakawa
Brain and Development 1992
Role of GH in regulating nocturnal rates of lipolysis and plasma mevalonate levels in normal and diabetic humans
PJ Boyle, A Avogaro, L Smith, DM Bier, AS Pappu, DR Illingworth, PE Cryer
American journal of physiology. Endocrinology and metabolism 1992
Clinical Pathophysiology of the Somatotropic (GH) Axis in Adults
A Iranmanesh, JD Veldhuis
Endocrinology and metabolism clinics of North America 1992
Biologische Psychiatrie
W Gaebel, G Laux
1992
Effects of pyridostigmine on spontaneous and growth hormone-releasing hormone stimulated growth hormone secretion in children on daily glucocorticoid therapy after liver transplantation
A Giustina, A Girelli, D Albert, S Bossonl, F Buzl, M Doga, M Schettino, WB Wehrenberg
Clinical Endocrinology 1991
Growth hormone and cortisol secretion in relation to sleep and wakefulness
JR Davidson, H Moldofsky, FA Lue
Journal of psychiatry & neuroscience : JPN 1991
Polygraphic sleep patterns and growth hormone secretion in children after cranial irradiation
I Fagioli, R Brauner, R Rappaport
European Journal of Pediatrics 1991
Reproducibility of 24-hour serum growth hormone profiles in man
S Saint, PC Hindmarsh, DR Matthews, PJ Pringle, J Jones, MA Preece, CG Brook
Clinical Endocrinology 1991
Comparison of Overnight Serum Human Growth Hormone (hGH) Secretory Profiles Measured by Three Different Methods
F P, WV Moore, JL Stevenson, DL Donaldson
Journal of Pediatric Endocrinology and Metabolism 1991
The functions of sleep: Further analysis
ZJ Cai
Physiology & Behavior 1991
Le Système de la Biochimie Comparée
E Schoffeniels
Archives Of Physiology And Biochemistry 1991
Acute effect of intravenous clomipramine upon sleep-related hormone secretion in depressed outpatients and healthy control subjects
DB Jarrett, B Pollock, JM Miewald, DJ Kupfer
Biological Psychiatry 1991
Nocturnal Cortisol, Thyroid Stimulating Hormone, and Growth Hormone Secretory Profiles in Depressed Adolescents
S Kutcher, D Malkin, J Silverberg, P Marton, P Williamson, A Malkin, J Szalai, M Katic
Journal of the American Academy of Child & Adolescent Psychiatry 1991
Lateralized rhythms of the central and autonomic nervous systems
D Shannahoff-Khalsa
International Journal of Psychophysiology 1991
A distribution method for analysing the baseline of pulsatile endocrine signals as exemplified by 24-hour growth hormone profiles
DR Matthews, PC Hindmarsh, PJ Pringle, CG Brook
Clinical Endocrinology 1991
Physiological growth hormone secretion in adult growth hormone deficiency: comparison with normal controls
HM Whitehead, B Aikent, S Lewis, B Sheridan, DR Haddon
Clinical Endocrinology 1991
Age-Related Alterations of the Growth Hormone/Insulin-Like-Growth-Factor I Axis
M Kelijman
Journal of the American Geriatrics Society 1991
The Effects of Adenotonsillectomy on Growth in Young Children
EF Williams, P Woo, R Miller, RM Kellman
Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery 1991
Generalisierte Tendomyopathie (Fibromyalgie)
W Müller
1991
OVERNIGHT URINARY GROWTH HORMONE MEASUREMENT IN THE DIAGNOSIS OF ACROMEGALY
H Lunt, J Tucker, H Bullen, C Gibbs, TJ Wilkin
Clinical Endocrinology 1990
Growth Hormone Secretion: Its Regulation and the Influence of Nutritional Factors
RJ Ross, CR Buchanan
Nutrition Research Reviews 1990
A reexamination of the relationship between growth hormone secretion and slow wave sleep using delta wave analysis
DB Jarrett, JB Greenhouse, JM Miewald, IB Fedorka, DJ Kupfer
Biological Psychiatry 1990
Diurnal rhythm in the plasma concentration of cortisol in paediatric patients with orthostatic dysregulation
H Shibasaki, T Furuta, Y Kasuya, T Okabe, T Katoh, T Kogo, T Hirayama
Biological Mass Spectrometry 1990
A Review and Appraisal of Deconvolution Methods to Evaluate in vivo Neuroendocrine Secretory Events
JD Veldhuis, ML Johnson
Journal of Neuroendocrinology 1990
THE INFLUENCE OF GROWTH HORMONE ON SLEEP IN ADULTS WITH GROWTH HORMONE DEFICIENCY
C Åströ, SA Pedersen, J Lindholm
Clinical Endocrinology 1990
Nocturnal growth hormone surges in type 1 diabetes mellitus are both sleep- and glycemia-dependent: assessment under continuous sleep monitoring
MS Ríos, I Navascués, A Ordóñez, J Sabán, A Núñez, M Sánchez, EG Austt
Diabetes Research and Clinical Practice 1990
Recurrent nocturnal hypoglycemia in an insulin-dependent diabetic patient receiving a small daily dose of insulin
JD Walker, G Viberti
The American Journal of Medicine 1990
Sleep habits and height at ages 5 to 11
MC Gulliford, CE Price, RJ Rona, S Chinn
Archives of disease in childhood 1990
Schlaf und Schlafstörungen
K Meier-Ewert, H Schulz
1990
Handbook of Developmental Psychopathology
M Lewis, SM Miller
1990
Psychoneuroendocrinology
CS Holmes
Psychoneuroendocrinology 1990
Interleukin-1 β and muramyl dipeptide can prevent decreased antibody response associated with sleep deprivation
R Brown, RJ Price, MG King, AJ Husband
Brain, Behavior, and Immunity 1989
PLASMA GROWTH HORMONE PROFILES AND SLEEP: A STUDY OF 13 TREATED ACROMEGALICS
H Boer, F Roelfsema, M Frölich, HA Kamphuisen, AP Seters
Clinical Endocrinology 1989
Neuroendocrine Control of Growth Hormone Secretion
VD Colonna, S Cella, V Locatelli, S Loche, E Ghigo, D Cocchi, E Müller
Acta Paediatrica 1989
Growth hormone secretory profiles: Variation on consecutive nights
DL Donaldson, JG Hollowell, F Pan, RA Gifford, WV Moore
The Journal of Pediatrics 1989
Advances in Growth Hormone and Growth Factor Research
EE MÜller, D Cocchi, V Locatelli
1989
Circadian variations in plasma renin activity, catecholamines and aldosterone during exercise in women
LA Stephenson, MA Kolka, R Francesconi, RR Gonzalez
European Journal of Applied Physiology and Occupational Physiology 1989
Catecholamines II
U Trendelenburg, N Weiner
1989
Sleep Deprivation and the Effect on Exercise Performance1:
T VanHelder, MW Radomski
Sports Medicine 1989
Fasting enhances growth hormone secretion and amplifies the complex rhythms of growth hormone secretion in man
KY Ho, JD Veldhuis, ML Johnson, R Furlanetto, WS Evans, KG Alberti, MO Thorner
Journal of Clinical Investigation 1988
Growth Response to Daily Subcutaneous Administration of Growth Hormone
K Kikuchi, M Sudo, A Miyarnoto, T Ohie, C Mori, H Mikawa
Pediatrics International 1988
Environmetal and Behavioral Influences on Affective Illness
TA Wehr, NE Rosenthal, DA Sack
Acta Psychiatrica Scandinavica 1988
Growth Hormone (GH) Secretion During Nocturnal Sleep and after Clonidine in Patients with Essential Hypertension
J Slsowińnska-Srzednicka, S Zgliczńanski, M Wierzbicki, P Soszyński, W Jeske
Clinical and Experimental Hypertension 1988
acute changes in sleep-related hormone secretion of depressed patients following oral imipramine
DB Jarrett, JM Miewald, DJ Kupfer
Biological Psychiatry 1988
MOTOR LEARNING AND ULTRADIAN SLEEP CYCLE: AN ELECTROENCEPHALOGRAPHIC STUDY OF TRAMPOLINERS
J Buchegger, A Meier-Koll
Perceptual and Motor Skills 1988
Unaltered Growth Hormone Response to Growth Hormone Releasing Hormone After Sleep in Man
M Batrinos, E Georgiadis, C PANITSA-FAFLIA, M Anapliotou, S PITOULIS, A Chatzioanidis
Acta Paediatrica 1988
Nocturnal Growth Hormone Secretion in Depressed Older Adolescents
SP Kutcher, P Williamson, J Silverberg, P Marton, D Malkin, A Malkin
Journal of the American Academy of Child & Adolescent Psychiatry 1988
Serum growth hormone release during a 60-hour period in growing pigs
P Dubreuil, H Lapierre, G Pelletier, D Petitclerc, Y Couture, P Gaudreau, J Morisset, P Brazeau
Domestic Animal Endocrinology 1988
The Advantage of Measuring Stimulated as Compared with Spontaneous Growth Hormone Levels in the Diagnosis of Growth Hormone Deficiency
SR Rose, JL Ross, M Uriarte, KM Barnes, FG Cassorla, GB Cutler
New England Journal of Medicine 1988
Sandostatin® in the Treatment of Acromegaly
AM Landolt, R Illig, J Zapt
Sandostatin® in the Treatment of Acromegaly 1988
Twelve-hour Spontaneous Nocturnal Growth Hormone Secretion in Growth Retarded Patients
GL Spadoni, S Cianfarani, S Bernardini, F Vaccaro, C Galasso, ML Bitti, F Costa, B Boscherini
Clinical Pediatrics 1988
Basic and Clinical Aspects of Growth Hormone
BB Bercu
1988
Mechanisms of Physical and Emotional Stress
GP Chrousos, DL Loriaux, PW Gold
1988
Verhaltensmedizin und Diabetes mellitus
F Strian, R Hölzl, M Haslbeck
1988
HLA in Narcolepsy
Y Honda, T Juji
1988
Schlaf-Wach-Funktionen
H Hippius, E Rüther, M Schmauss
1988
Somatostatin
SR Bloom, JM Polak
British medical journal (Clinical research ed.) 1987
Delta Sleep-Inducing Peptide (DSIP) stimulates Growth Hormone (GH) release in the rat by hypothalamic and pituitary actions
KS Iyer, SM McCann
Peptides 1987
THE RELATIONSHIP BETWEEN HEIGHT VELOCITY AND GROWTH HORMONE SECRETION IN SHORT PREPUBERTAL CHILDREN
P Hindmarsh, PJ Smith, CG Brook, DR Matthews
Clinical Endocrinology 1987
Physiology of the Somatotropic Axis with Particular Reference to the Ruminant
PD Gluckman, BH Breier, SR Davis
Journal of Dairy Science 1987
Delta sleep inducing peptide (DSIP) stimulates the release of LH but not FSH via a hypothalamic site of action in the rat
KS Iyer, SM McCann
Brain Research Bulletin 1987
Sleep and neuroendocrine correlates of affective illness in childhood and adolescence
J Puig-Antich
Journal of Adolescent Health Care 1987
Sommeil et exercice physique chez l'homme
A Buguet, J Lonsorfer
Science & Sports 1987
Dementia — The failure of hippocampal plasticity and dreams. Is there a preventative role for melatonin?
CP Maurizi
Medical Hypotheses 1987
Sleep Disruption: A Treatment for Depression and a Cause of Mania
TA Wehr, DA Sack
Psychiatric Annals 1987
Sleep Disorders in Tourette's Syndrome
R Sandyk, CR Bamford, RP Iacono
International Journal of Neuroscience 1987
Influence of the pineal gland on pituitary function in humans
ML Rao, T Mager
Psychoneuroendocrinology 1987
The Pituitary Gland
CR Kannan
1987
Serum Prolactin, Cortisol and Growth Hormone Concentrations after Various Epileptic Seizures
H Takeshita, R Kawahara, T Nagabuchi, R Mizukawa, H Hazama
Psychiatry and Clinical Neurosciences 1986
GROWTH HORMONE RESPONSE TO LOW DOSE INTRAVENOUS INJECTIONS OF GROWTH HORMONE RELEASING FACTOR IN OBESE AND NORMAL WEIGHT WOMEN
PG Kopelman, K Noonan
Clinical Endocrinology 1986
A life-sustaining function for REM sleep: A theory
RP Vertes
Neuroscience & Biobehavioral Reviews 1986
NOCTURNAL PULSATILE GROWTH HORMONE RELEASING HORMONE TREATMENT IN GROWTH HORMONE DEFICIENCY
PJ Smith, CG Brook, J Rivier, W Vale, MO Thorner
Clinical Endocrinology 1986
Intracerebroventricular infusion of somatostatin selectively increases paradoxical sleep in rats
J Danguir
Brain Research 1986
Laboratory Diagnosis of Hypopituitarism
CF Abboud
Mayo Clinic Proceedings 1986
Inactivity: Physiological Effects
H Sandler
Inactivity: Physiological Effects 1986
The importance of sleep and the sensory environment to critically ill patients
KS McGonigal
Intensive Care Nursing 1986
Clinical Endocrinology
A Labhart
Clinical Endocrinology 1986
Sleep EEG in growth disorders
BJ Taylor, CG Brook
Archives of disease in childhood 1986
Effects of Growth Hormone-Releasing Factor in the Brain
WB Wehrenberg, CL Ehlers
Science 1986
A dual effector theory of growth-hormone action
H Green, M Morikawa, T Mxon
Differentiation 1985
Behavioral Disorders Complicating Developmental Anomalies of the Brain: Sleep Behavioral Disorders
T HASHIMOTO
Congenital Anomalies 1985
IMPAIRED GROWTH HORMONE RESPONSE TO GROWTH HORMONE RELEASING FACTOR AND INSULIN-HYPOGLYCAEMIA IN OBESITY
PG Kopelman, K Noonan, R Goulton, AJ Forrest
Clinical Endocrinology 1985
COMPARISON BETWEEN A PHYSIOLOGICAL AND A PHARMACOLOGICAL STIMULUS OF GROWTH HORMONE SECRETION: RESPONSE TO STAGE IV SLEEP AND INSULIN-INDUCED HYPOGLYCAEMIA
PC Hindmarsh, BT Taylor, PJ Smith, PJ Pringle, CG Brook
The Lancet 1985
Temporal correlation of some endocrine circadian rhythms in elderly subjects
P Cugini, P Lucia, R Tomassini, C Letizia, G Murano, D Scavo, G Tamburrano, A Maldonato, F Halberg, A Schramm
Maturitas 1985
Ultradian Rhythms in Physiology and Behavior
H Schulz, P Lavie
1985
Hypothalamic control of GH secretion: pathophysiology and clinical implications.
Quabbe HJ
Acta Neurochirurgica 1985
Relationship between the three-hour-period sleep-wakefulness cycle and growth hormone secretion in the immature rat
M Kawakami, F Kimura, CW Tsai
The Journal of Physiology 1984
Brainstem control of the events of rem sleep
RP Vertes
Progress in Neurobiology 1984
Rest in poultry
HJ Blokhuis
Applied Animal Behaviour Science 1984
Endocrine Disorders
LH Rees
Endocrine Disorders 1984
Prolactin, Growth Hormone and Growth Responses in Boys with Attention Deficit Disorder and Hyperactivity Treated with Methylphenidate
LL Greenhill, J Puig-Antich, H Novacenko, M Solomon, C Anghern, J Florea, R Goetz, B Fiscina, EJ Sachar
Journal of the American Academy of Child Psychiatry 1984
Exaggerated Somatomedin-C Response to Human Growth Hormone Infusion in Patients with Type II Diabetes Mellitus
EO Grecu, M Spencer, VA White, BM Sheikholislam
The American Journal of the Medical Sciences 1984
Sleep Mechanisms
AA Borbély, JL Valatx
1984
Sleep, Benzodiazepines and Performance
I Hindmarch, H Ott, T Roth
1984
Peptides, Hormones, and Behavior
CB Nemeroff, AJ Dunn
1984
Correlation of growth hormone secretion to sleep in the immature rat
M Kawakami, F Kimura, CW Tsai
The Journal of Physiology 1983
Influence of Total Sleep Deprivation on Event-Related Potentials in Man
P Gauthier, C Gottesmann
Psychophysiology 1983
Progress in Brain Research
DE van Epps, L Saland, C Taylor, RC Williams
Progress in brain research 1983
Chronobiologic considerations in human growth hormone therapy
MC Matustik, RW Furlanetto, WJ Meyer
The Journal of Pediatrics 1983
The Physiological Basis of Memory
G Chapouthier
The Physiological Basis of Memory 1983
The Effects of Nocturnally Administered Stimulant Medication on EEG Sleep and Behavior in Hyperactive Children
I Chatoor, KC Wells, CK Conners, WT Seidel, D Shaw
Journal of the American Academy of Child Psychiatry 1983
Growth Hormone Treatment for Short Stature
GV Vliet, DM Styne, SL Kaplan, MM Grumbach
New England Journal of Medicine 1983
Pituitary secretions and wake–sleep cycle
P Passouant
Cephalalgia : an international journal of headache 1983
Neuroendocrinology of Aging
J Meites
1983
Sleep-induced growth hormone release--evaluation of a simple test for clinical use
JM King, DA Price
Archives of disease in childhood 1983
Motivation
E Satinoff, P Teitelbaum
1983
Regulation of episodic growth hormone secretion by the central epinephrine system. Studies in the chronically cannulated rat
LC Terry, WR Crowley, MD Johnson
Journal of Clinical Investigation 1982
Correlations of Some Physical Variables with REM Sleep and Slow Wave Sleep in Man
T Ohkawa, Y Nakazawa
Psychiatry and Clinical Neurosciences 1982
Disturbances of sleep and cognitive functioning in patients with dementia
RJ Loewenstein, H Weingartner, JC Gillin, W Kaye, M Ebert, WB Mendelson
Neurobiology of Aging 1982
SLEEP RELATED GROWTH HORMONE AND PROLACTIN SECRETION’IN CHILDREN DURING CONSTANT RATE ENTERAL NUTRITION
I Fagioli, P Czernichow, P Salzarulo, JM Bonardi, C Ricour, C Sachs, F Salomon
Acta Paediatrica 1982
Developmental trend of quiet sleep is altered by early human malnutrition and recovered by nutritional rehabilitation
P Salzarulo, I Fagioli, F Salomon, C Ricour
Early Human Development 1982
CNS Pharmacology Neuropeptides
WB Mendelson, JC Gillin, RJ Wyatt
CNS Pharmacology Neuropeptides 1982
Energy expenditure and restorative sleep
CM Shapiro
Biological Psychology 1982
Growth hormone release after acute amitriptyline administration to normal human subjects
P Schulz, GM Reaven, TF Blaschke
Psychopharmacology 1982
Growth Hormone, Prolactin, and Growth Responses in Hyperkinetic Males Treated with D-Amphetamine
LL Greenhill, J Puig-Antich, W Chambers, B Rubinstein, F Halpern, EJ Sachar
Journal of the American Academy of Child Psychiatry 1981
Nocturnal growth hormone and gonadotrophin secretion in growth retarded children with Crohn's disease
MJ Farthing, CA Campbell, J Walker-Smith, CR Edwards, LH Rees, AM Dawson
Gut 1981
Dose-related effects of phenobarbitone on human sleep-waking patterns
I Karacan, W Orr, T Roth, M Kramer, J Thornby, S Bingham, D Kay
British Journal of Clinical Pharmacology 1981
Protein synthesis in rat brain during sleep
C Shapiro, P Girdwood
Neuropharmacology 1981
Circadian Rhythms and the Human
DS Minors, JM Waterhouse
Circadian Rhythms and the Human 1981
Melatonin: Current Status and Perspectives
S Werner, K Brismar, L Wetterberg, P Eneroth
Melatonin: Current Status and Perspectives 1981
Circadian variation in plasma prolactin, gonadotropins, and testosterone in diabetic male patients with and without impotence*
A Zeidler, R Gelfand, J Draus, JK Tauscher, RT Chopp
Fertility and Sterility 1981
Effect of naloxone, a specific opioid inhibitor, on blood pressure fall during sleep
P Rubin, TF Blaschke, C Guilleminault
Circulation 1981
Human Pituitary Hormones
E van Cauter, G Copinschi
1981
EEG-Befunde, neuroendokrinologische und psychometrische Untersuchungen zur Carbamazepin-Wirkung
P Clarenbach, R Wachner, G Lucius, O Kanno, H Cramer
Archiv f�r Psychiatrie und Nervenkrankheiten 1981
Bromocriptine therapy in acromegaly. A long-term review of 35 cases
Y Sachdev, K Gopal, VK Garg
Postgraduate medical journal 1981
Neuroendocrine Regulation and Altered Behaviour
PD Hrdina, RL Singhal
1981
Regulatory Mechanisms of Synaptic Transmission
R Tapia, CW Cotman
1981
Rhythmic dentinogenesis in the rabbit incisor: Circadian, ultradian, and infradian periods
GD Rosenberg, DJ Simmons
Calcified Tissue International 1980
Biochemical regulation of sleep
M Monnier, JM Gaillard
Experientia 1980
Cockayne's Syndrome: Neuroendocrinological Studies
T Hashimota, N Kawano, K Hiura, J Suzue, T kokawa, K Fakuda, S Endo, M Tayama, Y Tamura, M Miyao, I Oshima
Pediatrics International 1980
Physiology in Sleep
JH Greenberg
Physiology in Sleep 1980
Amitriptyline-induced suppression of growth hormone in acromegaly
AR Glass, M Schaaf, RC Dimond
Psychoneuroendocrinology 1980
Imipramine and REM sleep: Cholinergic mediation in animals
SY Hill, RB Reyes, DJ Kupfer
Psychopharmacology 1980
The Pituitary Adenoma
KD Post, IM Jackson, S Reichlin
1980
Increased slow wave sleep in a hypopituitary dwarf
WP Tormey, AS Darragh
Postgraduate medical journal 1980
Validität klinisch-chemischer Befunde
H Lang, W Rick, H Büttner
1980
Hormonal Therapy in the Future A Kinetic Problem
JF Crigler
Journal of Paediatrics and Child Health 1979
ORAL CLONIDINE AS A GROWTH HORMONE STIMULATION TEST
I Gil-Ad, E Topper, Z Laron
The Lancet 1979
Acromegaly
L Lazarus
Australian and New Zealand Journal of Medicine 1979
The effects of diazepam on sleep, and on the nocturnal release of growth hormone, prolactin, ACTH and cortisol
WP Tormey, C Dolphin, AS Darragh
British Journal of Clinical Pharmacology 1979
A new approach of sleep and feeding behaviors in the laboratory rat
S Nicolaidis, J Danguir, P Mather
Physiology & Behavior 1979
Corticosteroid and growth hormone responses to methylamphetamine in depressive illness
SA Checkley
Psychological Medicine 1979
Sleep in herniorrhaphy patients
NB Kavey, KZ Altshuler
The American Journal of Surgery 1979
The effects of diazepam on sleep, and on the nocturnal release of growth hormone, prolactin, ACTH and cortisol [letter]
WP Tormey, C Dolphin, AS Darragh
British Journal of Clinical Pharmacology 1979
Restitution and human sleep: A critical review
JA Horne
Physiological Psychology 1979
The Functions of Sleep
H Solis, A Fernandez-Guardiola, C Valverde-R.
The Functions of Sleep 1979
Skeletal Research: an Experimental Approach
EA Tonna
Skeletal Research: an Experimental Approach 1979
Hypothalamic Hormones
EE Müller
Hypothalamic Hormones 1979
The regulation of insulin-induced and sleep-related human growth hormone secretion: A review
WB Mendelson, LS Jacobs, JC Gillin, RJ Wyatt
Psychoneuroendocrinology 1979
Nutritional Basis of Growth Failure in Children and Adolescents with Crohn's Disease
DG Kelts, RJ Grand, G Shen, JB Watkins, SL Werlin, C Boehme
Gastroenterology 1979
The Symptom of Insomnia: Causes and Cures
JC Ware
Psychiatric Annals 1979
Methscopolamine Inhibition of Sleep-Related Growth Hormone Secretion EVIDENCE FOR A CHOLINERGIC SECRETORY MECHANISM
WB Mendelson, N Sitaram, RJ Wyatt, JC Gillin, LS Jacobs
Journal of Clinical Investigation 1978
SIMULTANEOUS STUDY OF CORTISOL, GROWTH HORMONE AND PROLACTIN NYCTOHEMERAL VARIATIONS IN NORMAL AND OBESE SUBJECTS. INFLUENCE OF PROLONGED FASTING IN OBESITY
G Copinschi, MH Laet, JP Brion, R Leclercq, M L'hermite, C Robyn, E Virasoro, EV Cauter
Clinical Endocrinology 1978
THE EFFECT OF SHORT- AND LONG-TERM CORTICOSTEROID TREATMENT ON SLEEP-ASSOCIATED GROWTH HORMONE SECRETION
RW Motson, DN Glass, DA Smith, JR Daly
Clinical Endocrinology 1978
Pituitary function and growth hormone dynamics in acromegaloidism
RB Mims
Journal of the National Medical Association 1978
Changes in Sleep Pattern After Sleep Deprivation
Y Nakazawa, M Kotorii, M Ohshima, T Kotorii, H Hasuzawa
Psychiatry and Clinical Neurosciences 1978
Prevalence of growth hormone deficiency in children with cleft lip or palate
D Rudman, GT Davis, JH Priest, JH Patterson, MH Kutner, SB Heymsfield, RA Bethel
The Journal of Pediatrics 1978
Effects of haloperidol on afternoon sleep and on the secretion of growth hormone in man
P Clarenbach, R Prunkl, M Riegler, H Cramer
Neuroscience 1978
Growth Hormone, Prolactin and Cortisol Responses and Growth Patterns in Hyperkinetic Children Treated with Dextro-Amphetamine: Preliminary Findings
J Puig-Antich, LL Greenhill, J Sassin, EJ Sachar
Journal of the American Academy of Child Psychiatry 1978
Glucocorticosteroids and growth hormone secretion under physiological conditions and in states of steroid excess
KE v. Mhlendahl, B Weber, R Mller-Hess, S Korth-Schtz, H Helge
European Journal of Pediatrics 1978
Growth hormone release during sleep in growth-retarded children with normal response to pharmacological tests
E Cacciari, G Coccagna, A Cicognani, P Pirazzoli, R Gallassi, P Farneti, F Bernardi, F Zappulla, G Gobbi, P Verucchi
Archives of disease in childhood 1978
Environmental Endocrinology
I Assenmacher, DS Farner
1978
Limbic Mechanisms
KE Livingston, O Hornykiewicz
1978
Hormones and sleep
J Thomson, I Oswald
Current Medical Research and Opinion 1977
Plasma Nitrazepam Concentrations after an Acute Intake and their Correlation to Sedation and Serum Growth Hormone Levels
L Kangas, J Kanto, E Syvälahti
Acta Pharmacologica et Toxicologica 1977
Secretion of Human Growth Hormone and Insulin in Levodopa Test during Carbamazepine Therapy
E Syvälahti, S Pynnönen
Acta Pharmacologica et Toxicologica 1977
DIURNAL VARIATIONS IN PLASMA PROLACTIN, GROWTH HORMONE, CORTISOL AND BLOOD GLUCOSE IN LABILE DIABETES MELLITUS
J Drejer, C Hendriksen, LM Nielsen, C Binder, C Hagen, H Kehlet
Clinical Endocrinology 1977
Peptides and behavior
D Wied
Life Sciences 1977
Clinical Neuroendocrinology
CR Edwards
Clinical Neuroendocrinology 1977
Biochemical Correlates of Brain Structure and Function
B Siesjö
Biochemical Correlates of Brain Structure and Function 1977
Neurobiology of Sleep and Memory
JF Sassin
Neurobiology of Sleep and Memory 1977
Serum growth hormone levels in schizophrenic patients during sleep
E Syvlahti, A Pekkarinen
Journal of Neural Transmission 1977
Sleep is for tissue restoration
K Adam, I Oswald
Journal of the Royal College of Physicians of London 1977
Comparative Endocrinology of Prolactin
HD Dellmann, JA Johnson, DM Klachko
1977
Suppression by cyproheptadine of human growth hormone and cortisol secretion during sleep
K Chihara, Y Kato, K Maeda, S Matsukura, H Imura
Journal of Clinical Investigation 1976
Nocturnal growth hormone secretion in acromegaly and obesity without electroencephalographic monitoring
RB Mims, RJ Lopez
Journal of the National Medical Association 1976
Temperature and endocrine activity during sleep in man
U Beck, H Reinhardt, K Kendel, W Schmidt-Kessen
Archiv für Psychiatrie und Nervenkrankheiten 1976
Stress, Cardiac Activity and Sleep
M Anch, WC Orr, I Karacan
Journal of Human Stress 1976
Clinical studies of human growth hormone
AW Root
Pharmacology & Therapeutics Part C Clinical Pharmacology and Therapeutics 1976
Clinical studies of gonadotropins in the female
JL Vaitukaitis, GT Ross
Pharmacology & Therapeutics Part C Clinical Pharmacology and Therapeutics 1976
Nocturnal hormonal profiles in massive obesity, anorexia nervosa and normal females
RS Kalucy, AH Crisp, T Chard, A McNeilly, CN Chen, JH Lacey
Journal of Psychosomatic Research 1976
Proceedings of the Fourth International Congress on Hormonal Steroids
RK Kalkhoff
Proceedings of the Fourth International Congress on Hormonal Steroids 1976
The Sleep EEG in Neurological Diagnosis
WC Orr
1976
Effects of selective sleep deprivation on sleep-linked prolactin and growth hormone secretion
U Beck, D Marquetand, E Pozo, I Lancranjan
Archiv f�r Psychiatrie und Nervenkrankheiten 1976
Repeated circadian growth hormone, luteinizing hormone, and follicle-stimulating hormone in children: Influence of 9-alpha-fluorohydrocortisone
D Schnberg, R Kappler, W Ilg
European Journal of Nuclear Medicine 1976
Hypothalamus and Endocrine Functions
F Labrie, J Meites, G Pelletier
1976
The neurophysiological aspects of sleep
GW Fenton
Postgraduate medical journal 1976
The function of sleep
I Oswald
Postgraduate medical journal 1976
Peptide Hormones
JA Parsons
1976
Temperature and endocrine activity during sleep in man: Activation of cortisol and thyroid-stimulating hormone, inhibition of human growth hormone secretion by raised or decreased ambient and body temperatures
U Beck, H Reinhardt, K Kendel, W Schmidt-Kessen
Archiv f�r Psychiatrie und Nervenkrankheiten 1976
Suppression of sleep-related prolactin secretion and enhancement of sleep-related growth hormone secretion
WB Mendelson, LS Jacobs, JD Reichman, E Othmer, PE Cryer, B Trivedi, WH Daughaday
Journal of Clinical Investigation 1975
Neuropharmacologic control of neuroendocrine function in man
LA Frohman, ME Stachura
Metabolism 1975
ISOCALORIC DIET CHANGES AND ELECTROENCEPHALOGRAPHIC SLEEP
F Phillips, AH Crisp, B Mcguinness, EC Kalucy, CN Chen, J Koval, RS Kalucy, JH Lacey
The Lancet 1975
BIOCHEMICAL AND NEUROENDOCRINE ASPECTS OF EXPOSURE TO MICROWAVES
SM Michaelson, WM Houk, NJ Lebda, ST Lu, RL Magin
Annals of the New York Academy of Sciences 1975
Maternal growth hormone and growth and function
VR Sara, L Lazarus
Developmental Psychobiology 1975
Effects of growth hormone on sleep-waking patterns in cats
WC Stern, JE Jalowiec, H Shabshelowitz, PJ Morgane
Hormones and Behavior 1975
Pulsatile Secretion of ACTH, GH, LH and TSH in Man
J Leppäluoto, U Laisi, H Lybeck, J Partanen, T Ranta, P Virkkunen
Acta Physiologica Scandinavica 1975
Effects of growth hormone on brain biogenic amine levels
WC Stern, M Miller, JE Jalowiec, WB Forbes, PJ Morgane
Pharmacology Biochemistry and Behavior 1975
Ontogeny of luteinizing hormone and testosterone secretion
RM Boyar, RS Rosenfeld, JW Finkelstein, S Kapen, HP Roffwarg, ED Weitzman, L Hellman
Journal of Steroid Biochemistry 1975
Proceedings of the 1974 Laurentian Hormone Conference
H Valtin, HW Sokol, D Sunde
Proceedings of the 1974 Laurentian Hormone Conference 1975
Minireviews of the Neurosciences from Life Sciences
M Hamon, J Glowinski
Minireviews of the Neurosciences from Life Sciences 1975
A critical review of the clinical relevance of growth hormone and its measurement in the nuclear medicine laboratory
GM Brown, SH Kirpalani
Seminars in Nuclear Medicine 1975
Einundachtzigster Kongress
B Schlegel
1975
Biology of Aging and Development
GJ Thorbecke
1975
Biology of Brain Dysfunction
GE Gaull
1975
Selective impairment of growth hormone response to physiological stimuli
PH Wise, RB Burnet, TD Geary, H Berriman
Archives of disease in childhood 1975
Behavior and Brain Electrical Activity
N Burch, HL Altshuler
1975
Hypothalamic-Pituitary Function in Diverse Hyperprolactinemic States
RM Boyar, S Kapen, JW Finkelstein, M Perlow, JF Sassin, DK Fukushima, ED Weitzman, L Hellman
Journal of Clinical Investigation 1974
Suppression of Human Growth Hormone Secretion by Melatonin and Cyproheptadine
GA Smythe, L Lazarus
Journal of Clinical Investigation 1974
Human Puberty SIMULTANEOUS AUGMENTED SECRETION OF LUTEINIZING HORMONE AND TESTOSTERONE DURING SLEEP
RM Boyar, RS Rosenfeld, S Kapen, JW Finkelstein, HP Roffwarg, ED Weitzman, L Hellman
Journal of Clinical Investigation 1974
Nocturnal Secretory Patterns of FSH, GH, LH and TSH
PO Osterman, G Wallin, L Wide
Upsala Journal of Medical Sciences 1974
I ritmi biologici in diabetologia
A Pabis
Acta Diabetologica Latina 1974
Hormones and human sleep
JF Sassin
Journal of the National Medical Association 1974
Sex related diurnal variations in venous blood glucose and plasma insulin levels effects of estrogens in men
M Hautecouverture, G Slama, R Assan, G Tchobroutsky
Diabetologia 1974
Plasma testosterone during nocturnal sleep in normal men
RC Schiavi, DM Davis, D White, A Edwards, G Igel, C Fisherr
Steroids 1974
The neuroendocrinology of human sleep
RT Rubin, RE Poland, LE Rubin, PR Gouin
Life Sciences 1974
Cerebral dwarfism: Association of braindy sfunction with growth retardation
S Castells, KK Voeller, C Vinas, C Lu
The Journal of Pediatrics 1974
Theoretical view of REM sleep function: Maintenance of catecholamine systems in the central nervous system
WC Stern, PJ Morgane
Behavioral Biology 1974
The glucagon stimulation test: Effect on plasmagrowth hormone and on immunoreactive insulin, cortisol, and glucose in children
M Vanderschueren-Lodeweyckx, R Wolter, P Malvaux, E Eggermont, R Eeckels
The Journal of Pediatrics 1974
Advances in Steroid Biochemistry and Pharmacology
J Daly, J Evans
Advances in Steroid Biochemistry and Pharmacology 1974
Clinical applications of growth hormone assays
P H Sönksen
Journal of the Royal College of Physicians of London 1974
Neurohumoral Coding of Brain Function
RD Myers, RR Drucker-Colín
1974
Proceedings: Effect of corticotrophin and oral corticosteroids on nocturnally released growth hormone
R Motson, DN Glass, JI Evans, P Hill, JR Daly, N Rudolf
Annals of the rheumatic diseases 1973
Regolazione Della Secrezione Dell’ormone Somatotropo: Tentativo Di Interpretazione Unitaria
R Vigneri, S Squatrito, L Motta, V Pezzino, P Polosa
Acta Diabetologica Latina 1973
Gamma-hydroxybutyrate, succinic semialdehyde and sleep
H Laborit
Progress in Neurobiology 1973
A survey of growth hormone secretion and action
TJ Merimee, D Rabin
Metabolism 1973
Reduction of growth hormone secretion following clomiphene administration
M Perlow, J Sassin, R Boyar, L Hellman, ED Weitzman
Metabolism 1973
THE LEVEL AND CIRCADIAN RHYTHM OF PLASMA FREE 11-HYDROXYCORTICOIDS IN PATIENTS WITH LOCALIZED INTRACRANIAL PROCESSES, ESPECIALLY OF THE SELLAR REGION
PO Osterman, PO Lundberg, L Wlde
Acta Neurologica Scandinavica 1973
Relationship between sleep and growth in patients with reversible somatotropin deficiency (psychosocial dwarfism)1
G Wolff, J Money
Psychological Medicine 1973
Luteinizing hormone: Changes in secretory pattern during sleep in adult women
S Kapen, R Boyar, M Perlow, L Hellman, ED Weitzman
Life Sciences 1973
Circadian rhythm of immunoreactive insulin under glycemic stimulus
S Sensi, F Capani, P Caradonna, GB Dell'Acqua
Journal of Interdisiplinary Cycle Research 1973
Diurnal patterns of secretion of cortisol and growth hormone in normal adolescents, in patients with exogenous and endogenous Cushing's syndrome, in patients with diabetes mellitus, and in a fasting subject
AM Vazquez, J Schutt-Aine, AL Drash, FM Kenny, C Richards, D Anthony
The Journal of Pediatrics 1973
Comparison of diurnal variations in plasma glucose, cholesterol, triglyceride, insulin and in liver glycogen in younger and older chicks(Gallus domesticus)
KL Raheja
Comparative Biochemistry and Physiology Part A: Physiology 1973
The Effect of Acute Fasting on Sleep and the Sleep-Growth Hormone Response
I Karacan, AL Rosenbloom, JH Londono, PJ Salis, JI Thornby, RL Williams
Psychosomatics 1973
Neural Regulation of Growth Hormone Secretion
JB Martin
New England Journal of Medicine 1973
Growth and Development in Adolescence
MD Kogut
Pediatric Clinics of North America 1973
Nyctohemeral growth hormone levels in children with growth retardation and inflammatory bowel disease ,
RW Gotlin, RS Dubois
Gut 1973
Anesthetic Management of Endocrine Disease
T Oyama
1973
Hormones and Brain Function
K Lissák
1973
Growth hormone release during sleep in growth retarded children.
Eastman CJ, Lazarus L
Archives of disease in childhood 1973
Human Growth Hormone
JM Tanner
Nature 1972
Growth hormone. Control of release and characteristics in plasma
JC Beck, MR Bala, KA Ferguson, CF Kudo, D Rubinstein
Transactions of the American Clinical and Climatological Association 1972
Night and day growth hormone levels during treatment with corticosteroids and corticotrophin
SN Pantelakis, CA Sinaniotis, S Sbirakis, D Ikkos, SA Doxiadis
Archives of disease in childhood 1972
Persistence of rhythmic human growth hormone release during sleep in fasted and nonisocalorically fed normal subjects
DC Parker, LG Rossman, EF VanderLaan
Metabolism 1972
The temporal relation between high release and sleep stage changes at nocturnal sleep onset in man
MA Pawel, JF Sassin, ED Weitzman
Life Sciences 1972
Effect of cortisone therapy on the diurnal pattern of growth hormone secretion in congenital adrenal hyperplasia
AM Vazquez, JC Schutt-Aine, FM Kenny, C Richards, D Anthony
The Journal of Pediatrics 1972
Growth hormone and cortisol responsiveness in Cushing's syndrome
DT Krieger, SM Glick
The American Journal of Medicine 1972
Growth hormone and the steroid binding β-globulin of human plasma
PD Moor, W Heynes, R Bouillon
Journal of Steroid Biochemistry 1972
Clinical Neuropharmacology of Hypothalamic Releasing Factors
LA Frohman
New England Journal of Medicine 1972
Sleep and Puberty: Who Wakes the Bugler?
AB Rifkind
New England Journal of Medicine 1972
Circadian variation in blood glucose levels, in glucose tolerance and in plasma immunoreactive insulin levels
RJ Jarrett
Acta Diabetologica 1972
Achtundsiebzigster Kongress
B Schlegel
1972
Control of Renin Secretion
TA Assaykeen
1972
Advances in Climatic Physiology
S Itoh, K Ogata, H Yoshimura
1972
Human Prolactin: 24-Hour Pattern with Increased Release during Sleep
JF Sassin, AG Frantz, ED Weitzman, S Kapen
Science 1972
Gonadotropin Secretion during Sleep in Normal Adult Men
RT Rubin, A Kales, R Adler, T Fagan, W Odell
Science 1972
Diurnal fluctuations in triglyceride, free fatty acids, and insulin during sucrose consumption and insulin infusion in man
PJ Barter, KF Carroll, PJ Nestel
Journal of Clinical Investigation 1971
Comportamento nelle 24 ore della risposta insulinemica ad un costante e ripetuto carico di glucosio in soggetti normali
S Sensi, F Capani, P Caradonna, D Policicchio, M Carotenuto
Acta Diabetologica Latina 1971
Changing concepts on the control of growth hormone secretion in man
WP VanderLaan
California medicine 1971
Concentrations of Plasma Testosterone in Normal Men during Sleep
JI Evans, AW Maclean, AA Ismail, D Love
Nature 1971
THE EFFECTS OF REPEATED PROLONGED EXERCISE ON PLASMA GROWTH HORMONE, INSULIN, GLUCOSE, FREE FATTY ACIDS, GLYCEROL, LACTATE AND β-HYDROXYBUTYRIC ACID IN 13-YEAR OLD BOYS AND IN ADULTS
BO Eriksson, B Persson, JI Thorell
Acta Paediatrica 1971
Sulfation factor regulation of skeletal growth
WH Daughaday
The American Journal of Medicine 1971
Effect of Chlorpromazine on Serum Growth-Hormone Concentration in Man
L Sherman, S Kim, F Benjamin, HD Kolodny
New England Journal of Medicine 1971
Effects of prolonged bed rest on EEG sleep patterns in young, healthy volunteers
RS Ryback, OF Lewis
Electroencephalography and Clinical Neurophysiology 1971
Prediction of Drug Treatment Effective in Narcolepsy Based on Digital Computer Analyzed EEG
B Saletu, TM Itil, A Keskiner
Clinical Electroencephalography 1971
Comportamento nelle 24 ore della risposta insulinemica ad un costante e ripetuto carico di glucosio in soggetti normali
S Sensi, F Capani, P Caradonna, D Policicchio, M Carotenuto
Acta Diabetologica 1971
Effect of methoxyflurane anaesthesia and surgery on human growth hormone and insulin levels in plasma
T Oyama, T Takazawa
Canadian Anaesthetists’ Society Journal 1970
Urinary insulin II. Excretion in children and adults
SS Najjar, L Stephan
Metabolism 1970
Diurnal patterns of blood glucose, serum free fatty acids, insulin, glucagon and growth hormone in normals and juvenile diabetics
AP Hansen, K Johansen
Diabetologia 1970
Endokrinologie der Entwicklung und Reifung
J Kracht
1970
Metabolic clearance and production rates of human growth hormone
AL Taylor, JL Finster, DH Mintz
Journal of Clinical Investigation 1969
Effects of slow wave sleep deprivation on human growth hormone release in sleep: Preliminary study
JF Sassin, DC Parker, LC Johnson, LG Rossman, JW Mace, RW Gotlin
Life Sciences 1969
ABNORMAL GROWTH HORMONE RESPONSE TO INGESTION OF GLUCOSE IN JUVENILE DIABETICS
H Yde
Acta Medica Scandinavica 1969
Decreased 17-hydroxycorticosteroid and VMA excretion during sleep following glutethimide administration in man
RT Rubin, A Kales, BR Clark
Life Sciences 1969
Sleep: Biochemical Aspects
JA Hobson
New England Journal of Medicine 1969
Growth Hormone Assay in Acromegaly, Gigantism, Dwarfism and Hypopituitarism
WH Daughaday
Postgraduate Medicine 1969
Circadian variations of blood sugar and plasma insulin levels in man
C Malherbe, M de Gasparo, R de Hertogh, JJ Hoem
Diabetologia 1969
Human Growth Hormone Release: Relation to Slow-Wave Sleep and Sleep-Waking Cycles
JF Sassin, DC Parker, JW Mace, RW Gotlin, LC Johnson, LG Rossman
Science 1969
CHANGE OF PLASMA CORTICOSTERONE DURING SLEEP IN CATS
S TAKAHASHI, Y HONDA, K TAKAHASHI, T OKUMA
Psychiatry and Clinical Neurosciences 1968

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