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Research Article Free access | 10.1172/JCI105813
Department of Medicine, Albert Einstein College of Medicine, Bronx, New York 10461
Department of Pharmacology, Albert Einstein College of Medicine, Bronx, New York 10461
Find articles by Fulop, M. in: JCI | PubMed | Google Scholar
Department of Medicine, Albert Einstein College of Medicine, Bronx, New York 10461
Department of Pharmacology, Albert Einstein College of Medicine, Bronx, New York 10461
Find articles by Brazeau, P. in: JCI | PubMed | Google Scholar
Published May 1, 1968 - More info
Urinary inorganic phosphate excretion was studied before and during the administration of sodium bicarbonate and acetazolamide in dogs that were not given infusions of phosphate. The excretion fraction of filtered phosphate increased after sodium bicarbonate or acetazolamide was given. This phosphaturia was attributed to decreased tubular reabsorption of phosphate consequent to alkalinization of either tubular urine or cells.