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Difference in Hepatic Metabolism of Long- and Medium-Chain Fatty Acids: the Role of Fatty Acid Chain Length in the Production of the Alcoholic Fatty Liver
Charles S. Lieber, André Lefèvre, Norton Spritz, Lawrence Feinman, and Leonore M. DeCarli
Liver Disease and Nutrition Unit, Second (Cornell) Medical Division, Bellevue Hospital, and the Department of Medicine, Cornell University Medical College, New York
‡Recipient of a U. S. Public Health Service Research Career Development Award (K3-AM-22,590) from the National Institute of Arthritis and Metabolic Diseases.
§Established Investigator of the Health Research Council of the City of New York (I-128), Present address: The Rockefeller University, New York, N. Y.
ǁSupported by a Postdoctoral Research Traineeship in Gastroenterology (TI AM 5091) and a Research Fellowship (F2 AM29096-01) from the National Institute of Arthritis and Metabolic Diseases, U. S. Public Health Service.
Address requests for reprints to Dr. Charles S. Lieber, Director, Liver Disease and Nutrition Unit, Second (cornell) Medical Division, Bellevue Hospital, First Avenue and 26th Street, New York, N. Y. 10016.
*Submitted for publication 20 March 1967; accepted 8 June 1967.
Presented in part at the Annual Meeting of the American Gastroenterological Association, Chicago, May 1966 and published in abstract form (1). This study was supported in part by U. S. Public Health Service research grants AM09536, AM10893, and AM06284 from the National Institute of Arthritis and Metabolic Diseases and grant NB03345-04 from the National Institute of Neurological Diseases and Blindness.
Find articles by Lieber, C. in: JCI | PubMed | Google Scholar
Liver Disease and Nutrition Unit, Second (Cornell) Medical Division, Bellevue Hospital, and the Department of Medicine, Cornell University Medical College, New York
‡Recipient of a U. S. Public Health Service Research Career Development Award (K3-AM-22,590) from the National Institute of Arthritis and Metabolic Diseases.
§Established Investigator of the Health Research Council of the City of New York (I-128), Present address: The Rockefeller University, New York, N. Y.
ǁSupported by a Postdoctoral Research Traineeship in Gastroenterology (TI AM 5091) and a Research Fellowship (F2 AM29096-01) from the National Institute of Arthritis and Metabolic Diseases, U. S. Public Health Service.
Address requests for reprints to Dr. Charles S. Lieber, Director, Liver Disease and Nutrition Unit, Second (cornell) Medical Division, Bellevue Hospital, First Avenue and 26th Street, New York, N. Y. 10016.
*Submitted for publication 20 March 1967; accepted 8 June 1967.
Presented in part at the Annual Meeting of the American Gastroenterological Association, Chicago, May 1966 and published in abstract form (1). This study was supported in part by U. S. Public Health Service research grants AM09536, AM10893, and AM06284 from the National Institute of Arthritis and Metabolic Diseases and grant NB03345-04 from the National Institute of Neurological Diseases and Blindness.
Find articles by Lefèvre, A. in: JCI | PubMed | Google Scholar
Liver Disease and Nutrition Unit, Second (Cornell) Medical Division, Bellevue Hospital, and the Department of Medicine, Cornell University Medical College, New York
‡Recipient of a U. S. Public Health Service Research Career Development Award (K3-AM-22,590) from the National Institute of Arthritis and Metabolic Diseases.
§Established Investigator of the Health Research Council of the City of New York (I-128), Present address: The Rockefeller University, New York, N. Y.
ǁSupported by a Postdoctoral Research Traineeship in Gastroenterology (TI AM 5091) and a Research Fellowship (F2 AM29096-01) from the National Institute of Arthritis and Metabolic Diseases, U. S. Public Health Service.
Address requests for reprints to Dr. Charles S. Lieber, Director, Liver Disease and Nutrition Unit, Second (cornell) Medical Division, Bellevue Hospital, First Avenue and 26th Street, New York, N. Y. 10016.
*Submitted for publication 20 March 1967; accepted 8 June 1967.
Presented in part at the Annual Meeting of the American Gastroenterological Association, Chicago, May 1966 and published in abstract form (1). This study was supported in part by U. S. Public Health Service research grants AM09536, AM10893, and AM06284 from the National Institute of Arthritis and Metabolic Diseases and grant NB03345-04 from the National Institute of Neurological Diseases and Blindness.
Find articles by Spritz, N. in: JCI | PubMed | Google Scholar
Liver Disease and Nutrition Unit, Second (Cornell) Medical Division, Bellevue Hospital, and the Department of Medicine, Cornell University Medical College, New York
‡Recipient of a U. S. Public Health Service Research Career Development Award (K3-AM-22,590) from the National Institute of Arthritis and Metabolic Diseases.
§Established Investigator of the Health Research Council of the City of New York (I-128), Present address: The Rockefeller University, New York, N. Y.
ǁSupported by a Postdoctoral Research Traineeship in Gastroenterology (TI AM 5091) and a Research Fellowship (F2 AM29096-01) from the National Institute of Arthritis and Metabolic Diseases, U. S. Public Health Service.
Address requests for reprints to Dr. Charles S. Lieber, Director, Liver Disease and Nutrition Unit, Second (cornell) Medical Division, Bellevue Hospital, First Avenue and 26th Street, New York, N. Y. 10016.
*Submitted for publication 20 March 1967; accepted 8 June 1967.
Presented in part at the Annual Meeting of the American Gastroenterological Association, Chicago, May 1966 and published in abstract form (1). This study was supported in part by U. S. Public Health Service research grants AM09536, AM10893, and AM06284 from the National Institute of Arthritis and Metabolic Diseases and grant NB03345-04 from the National Institute of Neurological Diseases and Blindness.
Find articles by Feinman, L. in: JCI | PubMed | Google Scholar
Liver Disease and Nutrition Unit, Second (Cornell) Medical Division, Bellevue Hospital, and the Department of Medicine, Cornell University Medical College, New York
‡Recipient of a U. S. Public Health Service Research Career Development Award (K3-AM-22,590) from the National Institute of Arthritis and Metabolic Diseases.
§Established Investigator of the Health Research Council of the City of New York (I-128), Present address: The Rockefeller University, New York, N. Y.
ǁSupported by a Postdoctoral Research Traineeship in Gastroenterology (TI AM 5091) and a Research Fellowship (F2 AM29096-01) from the National Institute of Arthritis and Metabolic Diseases, U. S. Public Health Service.
Address requests for reprints to Dr. Charles S. Lieber, Director, Liver Disease and Nutrition Unit, Second (cornell) Medical Division, Bellevue Hospital, First Avenue and 26th Street, New York, N. Y. 10016.
*Submitted for publication 20 March 1967; accepted 8 June 1967.
Presented in part at the Annual Meeting of the American Gastroenterological Association, Chicago, May 1966 and published in abstract form (1). This study was supported in part by U. S. Public Health Service research grants AM09536, AM10893, and AM06284 from the National Institute of Arthritis and Metabolic Diseases and grant NB03345-04 from the National Institute of Neurological Diseases and Blindness.
Find articles by DeCarli, L. in: JCI | PubMed | Google Scholar
Published September 1, 1967 - More info
J Clin Invest. 1967;46(9):1451–1460. https://doi.org/10.1172/JCI105637.
© 1967 The American Society for Clinical Investigation
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ISSN: 0021-9738 (print), 1558-8238 (online)