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Article has an altmetric score of 12

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Referenced in 1 policy sources
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34 readers on Mendeley
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Research Article Free access | 10.1172/JCI105600

Pulmonary Mechanics during Pregnancy

J. Bernard L. Gee, Bernard S. Packer, J. Eugene Millen, and E. D. Robin

Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pa.

†

Address requests for reprints to Dr. J. Bernard L. Gee, Dept. of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pa. 15213.

‡

Fellow of the Pennsylvania Thoracic Society.

*

Submitted for publication November 7, 1966; accepted February 17, 1967.

This work was supported in part by grant HE-05059 from the National Institutes of Health and in part by a grant from the Tuberculosis League of Pittsburgh.

Find articles by Gee, J. in: JCI | PubMed | Google Scholar

Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pa.

†

Address requests for reprints to Dr. J. Bernard L. Gee, Dept. of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pa. 15213.

‡

Fellow of the Pennsylvania Thoracic Society.

*

Submitted for publication November 7, 1966; accepted February 17, 1967.

This work was supported in part by grant HE-05059 from the National Institutes of Health and in part by a grant from the Tuberculosis League of Pittsburgh.

Find articles by Packer, B. in: JCI | PubMed | Google Scholar

Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pa.

†

Address requests for reprints to Dr. J. Bernard L. Gee, Dept. of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pa. 15213.

‡

Fellow of the Pennsylvania Thoracic Society.

*

Submitted for publication November 7, 1966; accepted February 17, 1967.

This work was supported in part by grant HE-05059 from the National Institutes of Health and in part by a grant from the Tuberculosis League of Pittsburgh.

Find articles by Millen, J. in: JCI | PubMed | Google Scholar

Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pa.

†

Address requests for reprints to Dr. J. Bernard L. Gee, Dept. of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pa. 15213.

‡

Fellow of the Pennsylvania Thoracic Society.

*

Submitted for publication November 7, 1966; accepted February 17, 1967.

This work was supported in part by grant HE-05059 from the National Institutes of Health and in part by a grant from the Tuberculosis League of Pittsburgh.

Find articles by Robin, E. in: JCI | PubMed | Google Scholar

Published June 1, 1967 - More info

Published in Volume 46, Issue 6 on June 1, 1967
J Clin Invest. 1967;46(6):945–952. https://doi.org/10.1172/JCI105600.
© 1967 The American Society for Clinical Investigation
Published June 1, 1967 - Version history
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Abstract

Previously reported changes in static lung volumes during pregnancy have been confirmed.

Measurements of lung compliance (CL) and total pulmonary resistance (RL) were made in 10 women in the last trimester of pregnancy and 2 months postpartum, employing an esophageal balloon and recording spirometer. CL was unaffected by pregnancy, but RL was 50% below normal during pregnancy.

Measurements of airway conductance (CA) were made, employing the constant pressure body plethysmograph on 14 nonpregnant and 13 pregnant women. Specific airway conductance was increased during pregnancy.

Serial measurements of CA indicated a progressive increase beginning at about 6 months of gestation and a return to normal by 2 months postpartum.

The mechanism of the increased CA during pregnancy is not known. It may be related to changes in bronchial smooth muscle tone and conceivably explains the tolerance of certain patients with lung resections to pregnancy.

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Referenced in 1 policy sources
Referenced in 3 clinical guideline sources
34 readers on Mendeley
See more details