Isotopic Studies on Collagen Degradation and the Urine Excretion of Hydroxyproline

^{Department of Medicine, University of Pennsylvania, Philadelphia, Pa.}

^{Department of Biochemistry, University of Pennsylvania, Philadelphia, Pa.}

^{Philadelphia General Hospital, Philadelphia, Pa.}

Submitted for publication August 9, 1963; accepted November 14, 1963.

A preliminary report of this work has been presented (1). The studies were supported in part by U. S. Public Health Service grants A-5978 and AM-K3-14,916 from the National Institute of Arthritis and Metabolic Diseases.

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