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Myogenic stem cells for the therapy of primary myopathies: wishful thinking or therapeutic perspective?
Giulio Cossu, Fulvio Mavilio
Giulio Cossu, Fulvio Mavilio
Published June 15, 2000
Citation Information: J Clin Invest. 2000;105(12):1669-1674. https://doi.org/10.1172/JCI10376.
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Perspective

Myogenic stem cells for the therapy of primary myopathies: wishful thinking or therapeutic perspective?

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Abstract

Authors

Giulio Cossu, Fulvio Mavilio

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Figure 1

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A schematic representation of the possible origin of myogenic cells in r...
A schematic representation of the possible origin of myogenic cells in regenerating skeletal muscle. Regenerated fibers (characterized by centrally located nuclei) are formed by fusion of myogenic cells (dotted red) that may derive from resident, activated satellite cells (orange) or from cells derived from the microvasculature, either as circulating cells (violet), or as endothelial cells (light blue) or pericytes (yellow) of the vessel wall. A green nucleus symbolizes the activation of a myogenic program.

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