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Free access | 10.1172/JCI102366

THE MEASUREMENT OF TOTAL BODY WATER IN THE HUMAN SUBJECT BY DEUTERIUM OXIDE DILUTION : : WITH A CONSIDERATION OF THE DYNAMICS OF DEUTERIUM DISTRIBUTION

Paul R. Schloerb, Bent J. Friis-Hansen, Isidore S. Edelman, A. K. Solomon, and Francis D. Moore

Surgical Research Laboratories of the Peter Bent Brigham Hospital, Boston

Department of Surgery and the Biophysical Laboratory of the Harvard Medical School, Boston

2

Research Fellow in Surgery, Harvard Medical School; Assistant in Surgery, Peter Bent Brigham Hospital; formerly Atomic Energy Commission Postdoctoral Research Fellow in the Medical Sciences of the National Research Council.

3

Research Fellow in Surgery, Harvard Medical School; Assistant in Surgery, Peter Bent Brigham Hospital; Fellow of the American-Scandinavian Foundation.

4

Research Fellow in Surgery, Harvard Medical School; Assistant in Surgery, Peter Bent Brigham Hospital; formerly Atomic Energy Commission Postdoctoral Research Fellow in the Medical Sciences of the National Research Council.

5

Assistant Professor of Physical Chemistry, Biophysical Laboratory, Harvard Medical School.

6

Moseley Professor of Surgery, Harvard Medical School and Surgeon-in-Chief, Peter Bent Brigham Hospital.

1

This work was carried out with the support of the Atomic Energy Commission under a contract between the Office of Naval Research and Harvard University and directly by the Atomic Energy Commission under a contract with the Peter Bent Brigham Hospital. Heavy water used herein was generously provided through a grant from the American Cancer Society recommended by the Committee on Growth of the National Research Council. Support was also provided directly by the American Cancer Society through an Institutional Grant to the Harvard Medical School. Support was also generously provided by a grant from the Eugene Higgins Trust, through Harvard University and from the Massachusetts Heart Association.

Find articles by Schloerb, P. in: PubMed | Google Scholar

Surgical Research Laboratories of the Peter Bent Brigham Hospital, Boston

Department of Surgery and the Biophysical Laboratory of the Harvard Medical School, Boston

2

Research Fellow in Surgery, Harvard Medical School; Assistant in Surgery, Peter Bent Brigham Hospital; formerly Atomic Energy Commission Postdoctoral Research Fellow in the Medical Sciences of the National Research Council.

3

Research Fellow in Surgery, Harvard Medical School; Assistant in Surgery, Peter Bent Brigham Hospital; Fellow of the American-Scandinavian Foundation.

4

Research Fellow in Surgery, Harvard Medical School; Assistant in Surgery, Peter Bent Brigham Hospital; formerly Atomic Energy Commission Postdoctoral Research Fellow in the Medical Sciences of the National Research Council.

5

Assistant Professor of Physical Chemistry, Biophysical Laboratory, Harvard Medical School.

6

Moseley Professor of Surgery, Harvard Medical School and Surgeon-in-Chief, Peter Bent Brigham Hospital.

1

This work was carried out with the support of the Atomic Energy Commission under a contract between the Office of Naval Research and Harvard University and directly by the Atomic Energy Commission under a contract with the Peter Bent Brigham Hospital. Heavy water used herein was generously provided through a grant from the American Cancer Society recommended by the Committee on Growth of the National Research Council. Support was also provided directly by the American Cancer Society through an Institutional Grant to the Harvard Medical School. Support was also generously provided by a grant from the Eugene Higgins Trust, through Harvard University and from the Massachusetts Heart Association.

Find articles by Friis-Hansen, B. in: PubMed | Google Scholar

Surgical Research Laboratories of the Peter Bent Brigham Hospital, Boston

Department of Surgery and the Biophysical Laboratory of the Harvard Medical School, Boston

2

Research Fellow in Surgery, Harvard Medical School; Assistant in Surgery, Peter Bent Brigham Hospital; formerly Atomic Energy Commission Postdoctoral Research Fellow in the Medical Sciences of the National Research Council.

3

Research Fellow in Surgery, Harvard Medical School; Assistant in Surgery, Peter Bent Brigham Hospital; Fellow of the American-Scandinavian Foundation.

4

Research Fellow in Surgery, Harvard Medical School; Assistant in Surgery, Peter Bent Brigham Hospital; formerly Atomic Energy Commission Postdoctoral Research Fellow in the Medical Sciences of the National Research Council.

5

Assistant Professor of Physical Chemistry, Biophysical Laboratory, Harvard Medical School.

6

Moseley Professor of Surgery, Harvard Medical School and Surgeon-in-Chief, Peter Bent Brigham Hospital.

1

This work was carried out with the support of the Atomic Energy Commission under a contract between the Office of Naval Research and Harvard University and directly by the Atomic Energy Commission under a contract with the Peter Bent Brigham Hospital. Heavy water used herein was generously provided through a grant from the American Cancer Society recommended by the Committee on Growth of the National Research Council. Support was also provided directly by the American Cancer Society through an Institutional Grant to the Harvard Medical School. Support was also generously provided by a grant from the Eugene Higgins Trust, through Harvard University and from the Massachusetts Heart Association.

Find articles by Edelman, I. in: PubMed | Google Scholar

Surgical Research Laboratories of the Peter Bent Brigham Hospital, Boston

Department of Surgery and the Biophysical Laboratory of the Harvard Medical School, Boston

2

Research Fellow in Surgery, Harvard Medical School; Assistant in Surgery, Peter Bent Brigham Hospital; formerly Atomic Energy Commission Postdoctoral Research Fellow in the Medical Sciences of the National Research Council.

3

Research Fellow in Surgery, Harvard Medical School; Assistant in Surgery, Peter Bent Brigham Hospital; Fellow of the American-Scandinavian Foundation.

4

Research Fellow in Surgery, Harvard Medical School; Assistant in Surgery, Peter Bent Brigham Hospital; formerly Atomic Energy Commission Postdoctoral Research Fellow in the Medical Sciences of the National Research Council.

5

Assistant Professor of Physical Chemistry, Biophysical Laboratory, Harvard Medical School.

6

Moseley Professor of Surgery, Harvard Medical School and Surgeon-in-Chief, Peter Bent Brigham Hospital.

1

This work was carried out with the support of the Atomic Energy Commission under a contract between the Office of Naval Research and Harvard University and directly by the Atomic Energy Commission under a contract with the Peter Bent Brigham Hospital. Heavy water used herein was generously provided through a grant from the American Cancer Society recommended by the Committee on Growth of the National Research Council. Support was also provided directly by the American Cancer Society through an Institutional Grant to the Harvard Medical School. Support was also generously provided by a grant from the Eugene Higgins Trust, through Harvard University and from the Massachusetts Heart Association.

Find articles by Solomon, A. in: PubMed | Google Scholar

Surgical Research Laboratories of the Peter Bent Brigham Hospital, Boston

Department of Surgery and the Biophysical Laboratory of the Harvard Medical School, Boston

2

Research Fellow in Surgery, Harvard Medical School; Assistant in Surgery, Peter Bent Brigham Hospital; formerly Atomic Energy Commission Postdoctoral Research Fellow in the Medical Sciences of the National Research Council.

3

Research Fellow in Surgery, Harvard Medical School; Assistant in Surgery, Peter Bent Brigham Hospital; Fellow of the American-Scandinavian Foundation.

4

Research Fellow in Surgery, Harvard Medical School; Assistant in Surgery, Peter Bent Brigham Hospital; formerly Atomic Energy Commission Postdoctoral Research Fellow in the Medical Sciences of the National Research Council.

5

Assistant Professor of Physical Chemistry, Biophysical Laboratory, Harvard Medical School.

6

Moseley Professor of Surgery, Harvard Medical School and Surgeon-in-Chief, Peter Bent Brigham Hospital.

1

This work was carried out with the support of the Atomic Energy Commission under a contract between the Office of Naval Research and Harvard University and directly by the Atomic Energy Commission under a contract with the Peter Bent Brigham Hospital. Heavy water used herein was generously provided through a grant from the American Cancer Society recommended by the Committee on Growth of the National Research Council. Support was also provided directly by the American Cancer Society through an Institutional Grant to the Harvard Medical School. Support was also generously provided by a grant from the Eugene Higgins Trust, through Harvard University and from the Massachusetts Heart Association.

Find articles by Moore, F. in: PubMed | Google Scholar

Published October 1, 1950 - More info

Published in Volume 29, Issue 10 on October 1, 1950
J Clin Invest. 1950;29(10):1296–1310. https://doi.org/10.1172/JCI102366.
© 1950 The American Society for Clinical Investigation
Published October 1, 1950 - Version history
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Referenced in 1 policy sources
Referenced in 18 patents
28 readers on Mendeley
See more details