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Research Article Free access | 10.1172/JCI101970

COMPARISON OF CHLOROQUINE, QUINACRINE (ATABRINE), AND QUININE IN THE TREATMENT OF ACUTE ATTACKS OF SPOROZOITE-INDUCED VIV AX MALARIA (CHESSON STRAIN)

Theodore N. Pullman, Branch Craige Jr., Alf S. Alving, C. Merrill Whorton, Ralph Jones Jr., and Lillian Eichelberger

Malarial Research Unit, Department of Medicine, University of Chicago

2

Captain, M.C., A.U.S.

1

This investigation was carried out under a contract, recommended by the Committee on Medical Research, between the Office of Scientific Research and Development and the University of Chicago. The work was planned in cooperation with the Panel on Clinical Testing of Antimalarials of the Board for Coordination of Malarial Studies. This work was further aided by the participation of Army Medical Officers assigned to the project by the Surgeon General, U. S. Army.

The authors express their thanks to the Malaria Study Section of the National Institute of Health for editorial assistance and for arrangements in regard to the publication of this paper. They are also grateful to the Abbott Laboratories, E. I. du Pont de Nemours and Company, Inc., E. R. Squibb and Sons, Eli Lilly and Company, Sharp and Dohme, Inc., and Wyeth, Inc., for contributing toward the publication costs.

Find articles by Pullman, T. in: JCI | PubMed | Google Scholar

Malarial Research Unit, Department of Medicine, University of Chicago

2

Captain, M.C., A.U.S.

1

This investigation was carried out under a contract, recommended by the Committee on Medical Research, between the Office of Scientific Research and Development and the University of Chicago. The work was planned in cooperation with the Panel on Clinical Testing of Antimalarials of the Board for Coordination of Malarial Studies. This work was further aided by the participation of Army Medical Officers assigned to the project by the Surgeon General, U. S. Army.

The authors express their thanks to the Malaria Study Section of the National Institute of Health for editorial assistance and for arrangements in regard to the publication of this paper. They are also grateful to the Abbott Laboratories, E. I. du Pont de Nemours and Company, Inc., E. R. Squibb and Sons, Eli Lilly and Company, Sharp and Dohme, Inc., and Wyeth, Inc., for contributing toward the publication costs.

Find articles by Craige, B. in: JCI | PubMed | Google Scholar

Malarial Research Unit, Department of Medicine, University of Chicago

2

Captain, M.C., A.U.S.

1

This investigation was carried out under a contract, recommended by the Committee on Medical Research, between the Office of Scientific Research and Development and the University of Chicago. The work was planned in cooperation with the Panel on Clinical Testing of Antimalarials of the Board for Coordination of Malarial Studies. This work was further aided by the participation of Army Medical Officers assigned to the project by the Surgeon General, U. S. Army.

The authors express their thanks to the Malaria Study Section of the National Institute of Health for editorial assistance and for arrangements in regard to the publication of this paper. They are also grateful to the Abbott Laboratories, E. I. du Pont de Nemours and Company, Inc., E. R. Squibb and Sons, Eli Lilly and Company, Sharp and Dohme, Inc., and Wyeth, Inc., for contributing toward the publication costs.

Find articles by Alving, A. in: JCI | PubMed | Google Scholar

Malarial Research Unit, Department of Medicine, University of Chicago

2

Captain, M.C., A.U.S.

1

This investigation was carried out under a contract, recommended by the Committee on Medical Research, between the Office of Scientific Research and Development and the University of Chicago. The work was planned in cooperation with the Panel on Clinical Testing of Antimalarials of the Board for Coordination of Malarial Studies. This work was further aided by the participation of Army Medical Officers assigned to the project by the Surgeon General, U. S. Army.

The authors express their thanks to the Malaria Study Section of the National Institute of Health for editorial assistance and for arrangements in regard to the publication of this paper. They are also grateful to the Abbott Laboratories, E. I. du Pont de Nemours and Company, Inc., E. R. Squibb and Sons, Eli Lilly and Company, Sharp and Dohme, Inc., and Wyeth, Inc., for contributing toward the publication costs.

Find articles by Whorton, C. in: JCI | PubMed | Google Scholar

Malarial Research Unit, Department of Medicine, University of Chicago

2

Captain, M.C., A.U.S.

1

This investigation was carried out under a contract, recommended by the Committee on Medical Research, between the Office of Scientific Research and Development and the University of Chicago. The work was planned in cooperation with the Panel on Clinical Testing of Antimalarials of the Board for Coordination of Malarial Studies. This work was further aided by the participation of Army Medical Officers assigned to the project by the Surgeon General, U. S. Army.

The authors express their thanks to the Malaria Study Section of the National Institute of Health for editorial assistance and for arrangements in regard to the publication of this paper. They are also grateful to the Abbott Laboratories, E. I. du Pont de Nemours and Company, Inc., E. R. Squibb and Sons, Eli Lilly and Company, Sharp and Dohme, Inc., and Wyeth, Inc., for contributing toward the publication costs.

Find articles by Jones, R. in: JCI | PubMed | Google Scholar

Malarial Research Unit, Department of Medicine, University of Chicago

2

Captain, M.C., A.U.S.

1

This investigation was carried out under a contract, recommended by the Committee on Medical Research, between the Office of Scientific Research and Development and the University of Chicago. The work was planned in cooperation with the Panel on Clinical Testing of Antimalarials of the Board for Coordination of Malarial Studies. This work was further aided by the participation of Army Medical Officers assigned to the project by the Surgeon General, U. S. Army.

The authors express their thanks to the Malaria Study Section of the National Institute of Health for editorial assistance and for arrangements in regard to the publication of this paper. They are also grateful to the Abbott Laboratories, E. I. du Pont de Nemours and Company, Inc., E. R. Squibb and Sons, Eli Lilly and Company, Sharp and Dohme, Inc., and Wyeth, Inc., for contributing toward the publication costs.

Find articles by Eichelberger, L. in: JCI | PubMed | Google Scholar

Published May 1, 1948 - More info

Published in Volume 27, Issue 3 on May 1, 1948
J Clin Invest. 1948;27(3):46–50. https://doi.org/10.1172/JCI101970.
© 1948 The American Society for Clinical Investigation
Published May 1, 1948 - Version history
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