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J P Iredale, … , C Hovell, M J Arthur
Published August 1, 1998
Citation Information: J Clin Invest. 1998;102(3):538-549. https://doi.org/10.1172/JCI1018.
Citation Information: J Clin Invest. 1998;102(3):538-549. https://doi.org/10.1172/JCI1018.
Abstract
Liver fibrosis results from the excessive secretion of matrix proteins by hepatic stellate cells (HSC), which proliferate during fibrotic liver injury. We have studied a model of spontaneous recovery from liver fibrosis to determine the biological mechanisms mediating resolution. Livers were harvested from rats at 0, 3, 7, and 28 d of spontaneous recovery from liver fibrosis induced by 4 wk of twice weekly intraperitoneal injections with CCl4. Hydroxyproline analysis and histology of liver sections indicated that the advanced septal fibrosis observed at time 0 (peak fibrosis) was remodeled over 28 d of recovery to levels close to control (untreated liver). alpha-Smooth muscle actin staining of liver sections demonstrated a 12-fold reduction in the number of activated HSC over the same time period with evidence of HSC apoptosis. Ribonuclease protection analysis of liver RNA extracted at each recovery time point demonstrated a rapid decrease in expression of the collagenase inhibitors TIMP-1 and TIMP-2, whereas collagenase mRNA expression remained at levels comparable to peak fibrosis. Collagenase activity in liver homogenates increased through recovery. We suggest that apoptosis of activated HSC may vitally contribute to resolution of fibrosis by acting as a mechanism for removing the cell population responsible for both producing fibrotic neomatrix and protecting this matrix from degradation via their production of TIMPs.
Authors
J P Iredale, R C Benyon, J Pickering, M McCullen, M Northrop, S Pawley, C Hovell, M J Arthur
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Citations to this article (847)
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The Effect of Splenectomy on the Reversal of Cirrhosis: a Prospective Study
DB Zeng, L Di, RC Zhang, QL Guo, BW Duan, CY Jia, F Chen, DD Lin, Y Zang, SC Lu |
Gastroenterology Research and Practice | 2019 |
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Extracts from Fermented Black Garlic Exhibit a Hepatoprotective Effect on Acute Hepatic Injury
JC Tsai, YA Chen, JT Wu, KC Cheng, PS Lai, KF Liu, YK Lin, YT Huang, CW Hsieh |
Molecules (Basel, Switzerland) | 2019 |
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Hesperetin derivative attenuates CCl4-induced hepatic fibrosis and inflammation by Gli-1-dependent mechanisms
X Chen, XF Li, Y Chen, S Zhu, HD Li, SY Chen, JN Wang, XY Pan, FT Bu, C Huang, J Li |
International Immunopharmacology | 2019 |
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The Evolving Landscape of Liver Cirrhosis Management
H Yoshiji, K Kaji |
2019 | |
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LIVER FIBROSIS: MECHANISMS AND THERAPY APPROACHES
AT Fiyas, NF Vasilevskaya, EF Pishchyk |
2019 | |
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Resolution of organ fibrosis
Joon-Il Jun, Lester F. Lau |
Journal of Clinical Investigation | 2018 |
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Soluble CD74 Reroutes MIF/CXCR4/AKT‐Mediated Survival of Cardiac Myofibroblasts to Necroptosis
J Soppert, S Kraemer, C Beckers, L Averdunk, J Möllmann, B Denecke, A Goetzenich, G Marx, J Bernhagen, C Stoppe |
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease | 2018 |
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Protective Effect of Octylmethoxycinnamate against UV-Induced Photoaging in Hairless Mouse via the Regulation of Matrix Metalloproteinases
S Kim, S Lamichhane, JH Ju, J Yun |
International journal of molecular sciences | 2018 |
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Endotoxin regulates matrix genes increasing reactive oxygen species generation by intercellular communication between palmitate-treated hepatocyte and stellate cell: DORNAS et al
W Dornas, D Glaise, A Bodin, A Sharanek, A Burban, DL Guillou, S Robert, S Dutertre, C Aninat, A Corlu, V Lagente |
Journal of Cellular Physiology | 2018 |
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Mouse models of hepatocellular carcinoma: an overview and highlights for immunotherapy research
ZJ Brown, B Heinrich, TF Greten |
Nature Reviews Gastroenterology & Hepatology | 2018 |
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Food components with antifibrotic activity and implications in prevention of liver disease
M Bae, YK Park, JY Lee |
The Journal of Nutritional Biochemistry | 2018 |
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Tipping the balance
L Drew |
Nature | 2018 |
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Triggering and resolution of inflammation in NASH
S Schuster, D Cabrera, M Arrese, AE Feldstein |
Nature Reviews Gastroenterology & Hepatology | 2018 |
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Are we any closer to treating liver fibrosis (and if no, why not)?
R Feng, X Yuan, C Shao, H Ding, R Liebe, HL Weng |
Journal of Digestive Diseases | 2018 |
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Liver fibrosis
MM Aydin, KC Akcali |
TURK J GASTROENTEROL | 2018 |
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Targeting Endothelial Erk1/2-Akt Axis as a Regeneration Strategy to Bypass Fibrosis during Chronic Liver Injury in Mice
Y Lao, Y Li, P Zhang, Q Shao, W Lin, B Qiu, Y Lv, L Tang, S Su, H Zhang, C Tian, A Sun, H Wei, P Zhang, Y Wu, Y Jiang, F He |
Molecular Therapy | 2018 |
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Succinate induces hepatic fibrogenesis by promoting activation, proliferation, and migration, and inhibiting apoptosis of hepatic stellate cells
SY Park, CT Le, KY Sung, DH Choi, EH Cho |
Biochemical and Biophysical Research Communications | 2018 |
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Succinate as a Regulator of Hepatic Stellate Cells in Liver Fibrosis
EH Cho |
Frontiers in Endocrinology | 2018 |
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Anti-fibrotic impact of Carvedilol in a CCl-4 model of liver fibrosis via serum microRNA-200a/SMAD7 enhancement to bridle TGF-β1/EMT track
SA El-Wakeel, RM Rahmo, HS El-Abhar |
Scientific Reports | 2018 |
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Acute lung injury by gastric fluid instillation: activation of myofibroblast apoptosis during injury resolution
P Ayala, J Torres, R Vivar, M Meneses, P Olmos, TS Martin, GR Borzone |
Respiratory Research | 2018 |
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Hepatic elastin content is predictive of adverse outcome in advanced fibrotic liver disease
TJ Kendall, GE Dolman, CM Duff, EC Paish, A Zaitoun, W Irving, JA Fallowfield, IN Guha |
Histopathology | 2018 |
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11Beta-hydroxysteroid dehydrogenase-1 deficiency or inhibition enhances hepatic myofibroblast activation in murine liver fibrosis
X Zou, P Ramachandran, TJ Kendall, A Pellicoro, E Dora, RL Aucott, K Manwani, TY Man, KE Chapman, NC Henderson, SJ Forbes, SP Webster, JP Iredale, BR Walker, Z Michailidou |
Hepatology | 2018 |
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Enhancing the apoptotic effect of IL-24/mda-7 on the human hepatic stellate cell through RGD peptide modification
I Jamhiri, S Zahri, D Mehrabani, Z Khodabandeh, M Dianatpour, R Yaghobi, SY Hosseini |
Immunological Investigations | 2018 |
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Hepatic fibrosis: It is time to go with hepatic stellate cell-specific therapeutic targets
D Ezhilarasan, E Sokal, M Najimi |
Hepatobiliary & pancreatic diseases international : HBPD INT | 2018 |
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Prospects in non-invasive assessment of liver fibrosis: Liquid biopsy as the future gold standard?
J Lambrecht, S Verhulst, I Mannaerts, H Reynaert, LA van Grunsven |
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease | 2018 |
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Therapeutic approaches to control tissue repair and fibrosis: Extracellular matrix as a game changer
M Walraven, B Hinz |
Matrix biology : journal of the International Society for Matrix Biology | 2018 |
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Artesunate may inhibit liver fibrosis via the FAK/Akt/β-catenin pathway in LX-2 cells
J Lv, R Bai, L Wang, J Gao, H Zhang |
BMC Pharmacology and Toxicology | 2018 |
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Investigation of the hepatoprotective effect of Corydalis saxicola Bunting on carbon tetrachloride-induced liver fibrosis in rats by 1H-NMR-based metabonomics and network pharmacology approaches
XW Liu, CL Tang, H Zheng, JX Wu, F Wu, YY Mo, , HJ Zhu, CL Yin, B Cheng, JX Ruan, FM Song, ZN Chen, H Song, HW Guo, YH Liang, ZH Su |
Journal of Pharmaceutical and Biomedical Analysis | 2018 |
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The congenital clubfoot – immunohistological analysis of the extracellular matrix
A Kerling, G Stoltenburg-Didinger, L Grams, U Tegtbur, H Horstmann, M Kück, H Mellerowicz |
Orthopedic Research and Reviews | 2018 |
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Stellate Cells in Tissue Repair, Inflammation, and Cancer
MH Sherman |
Annual Review of Cell and Developmental Biology | 2018 |
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Angiotensin II: a key mediator in the development of liver fibrosis and cancer
S Saber |
2018 | |
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The Human Gut-Liver-Axis in Health and Disease
A Krag, T Hansen |
2018 | |
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Targeted Therapy of Colorectal Cancer Subtypes
P Jordan |
2018 | |
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Loss of Prolyl-Hydroxylase 1 Protects against Biliary Fibrosis via Attenuated Activation of Hepatic Stellate Cells
MJ Strowitzki, J Kirchberg, C Tuffs, M Schiedeck, AS Ritter, M Biller, JM Harnoss, F Lasitschka, T Schmidt, P Radhakrishnan, A Ulrich, M Schneider |
The American Journal of Pathology | 2018 |
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Information, Computer and Application Engineering
HC Liu, WP Sung, W Yao |
2018 | |
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Effects of exogenous thymosin β4 on carbon tetrachloride-induced liver injury and fibrosis
X Li, L Wang, C Chen |
Scientific Reports | 2017 |
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Mechanisms of hepatic stellate cell activation
T Tsuchida, SL Friedman |
Nature Reviews Gastroenterology & Hepatology | 2017 |
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Sphingosine-1-Phosphate Prevents Egress of Hematopoietic Stem Cells From Liver to Reduce Fibrosis
A King, DD Houlihan, D Kavanagh, D Haldar, N Luu, A Owen, S Suresh, NN Than, G Reynolds, J Penny, H Sumption, P Ramachandran, NC Henderson, N Kalia, J Frampton, DH Adams, PN Newsome |
Gastroenterology | 2017 |
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Reversal of liver cirrhosis: current evidence and expectations
YK Jung, HJ Yim |
The Korean Journal of Internal Medicine | 2017 |
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Boosting the hypoxic response in myeloid cells accelerates resolution of fibrosis and regeneration of the liver in mice
C Kantari-Mimoun, E Krzywinska, M Castells, C Milien, R Klose, AK Meinecke, U Lemberger, T Mathivet, M Gojkovic, K Schrödter, C Österreicher, J Fandrey, H Rundqvist, C Stockmann |
Oncotarget | 2017 |
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ASPP2 Inhibits the Profibrotic Effects of Transforming Growth Factor-β1 in Hepatic Stellate Cells by Reducing Autophagy
M Lin, Y Chang, F Xie, Y Shi, L Pang, D Chen |
Digestive Diseases and Sciences | 2017 |
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The HLF/IL-6/STAT3 feedforward circuit drives hepatic stellate cell activation to promote liver fibrosis
DM Xiang, W Sun, BF Ning, TF Zhou, XF Li, W Zhong, Z Cheng, MY Xia, X Wang, X Deng, W Wang, HY Li, XL Cui, SC Li, B Wu, WF Xie, HY Wang, J Ding |
Gut | 2017 |
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A comparative analysis of the molecular basis of fibrosis between tissues
R Miller, M Fell, J Pleat |
Comparative Clinical Pathology | 2017 |
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Methylation of Septin9 mediated by DNMT3a enhances hepatic stellate cells activation and liver fibrogenesis
Y Wu, F Bu, H Yu, W Li, C Huang, X Meng, L Zhang, T Ma, J Li |
Toxicology and Applied Pharmacology | 2017 |
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Effect of ginseng extract on the TGF-β1 signaling pathway in CCl4-induced liver fibrosis in rats
MM Hafez, SS Hamed, MF El-Khadragy, ZK Hassan, SS Rejaie, MM Sayed-Ahmed, NO Al-Harbi, KA Al-Hosaini, MM Al-Harbi, AR Alhoshani, OA Al-Shabanah, SD Alsharari |
BMC complementary and alternative medicine | 2017 |
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Quantitative Proteomic analysis on Activated Hepatic Stellate Cells reversion Reveal STAT1 as a key regulator between Liver Fibrosis and recovery
H Zhang, F Chen, X Fan, C Lin, Y Hao, H Wei, W Lin, Y Jiang, F He |
Scientific Reports | 2017 |
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Management of Cirrhotic Patients After Successful HCV Eradication
RM Kwok, TT Tran |
Current Treatment Options in Gastroenterology | 2017 |
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The stellate cell system (vitamin A-storing cell system)
H Senoo, Y Mezaki, M Fujiwara |
Anatomical Science International | 2017 |
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Reversal of liver fibrosis: from fiction to reality
ME Zoubek, C Trautwein, P Strnad |
Best Practice & Research Clinical Gastroenterology | 2017 |
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Evaluation of serum fibrotic markers; CTGF, IL-17and TGF-β1 versus liver biopsy for detection of hepatic fibrosis in Egyptian patients with chronic hepatitis C
SK Kassim, SM Kamal, HH Shehata, MM Salib, ML Louka, MM Sallam, LM Nabegh |
Meta Gene | 2017 |
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Apocynin prevented inflammation and oxidative stress in carbon tetra chloride induced hepatic dysfunction in rats
MM Rahman, AY Muse, DM Khan, IH Ahmed, N Subhan, HM Reza, MA Alam, L Nahar, SD Sarker |
Biomedicine & Pharmacotherapy | 2017 |
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The Delivery of Small Interfering RNA to Hepatic Stellate Cells Using a Lipid Nanoparticle Composed of a Vitamin A-Scaffold Lipid-Like Material
N Toriyabe, Y Sakurai, A Kato, S Yamamoto, K Tange, Y Nakai, H Akita, H Harahsima |
Journal of Pharmaceutical Sciences | 2017 |
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No significant impact of Foxf1 siRNA treatment in acute and chronic CCl 4 liver injury
K Abshagen, T Rotberg, B Genz, B Vollmar |
Experimental biology and medicine (Maywood, N.J.) | 2017 |
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No significant impact of Foxf1 siRNA treatment in acute and chronic CCl 4 liver injury
K Abshagen, T Rotberg, B Genz, B Vollmar |
Experimental biology and medicine (Maywood, N.J.) | 2017 |
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Mechanisms involved in liver damage resolution after hepatitis C virus clearance
TB Salas-Villalobos, SA Lozano-Sepúlveda, AR Rincón-Sánchez, M Govea-Salas, AM Rivas-Estilla |
Medicina Universitaria | 2017 |
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Fibroblast growth factor 2 (FGF2) regulates cytoglobin expression and activation of human hepatic stellate cells via JNK signaling
M Sato-Matsubara, T Matsubara, A Daikoku, Y Okina, L Longato, K Rombouts, LT Thuy, J Adachi, T Tomonaga, K Ikeda, K Yoshizato, M Pinzani, N Kawada |
The Journal of biological chemistry | 2017 |
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Molecules, Systems and Signaling in Liver Injury
WX Ding, XM Yin |
Molecules, Systems and Signaling in Liver Injury | 2017 |
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Diabetes and Aging-related Complications
S Yamagishi |
Diabetes and Aging-related Complications | 2017 |
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Matrix metalloproteinase functions in hepatic injury and fibrosis
M Roderfeld |
Matrix Biology | 2017 |
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Serum level of interleukin-6 (IL-6) and N-terminal propeptide of procollagen type I (PINP) in patients with liver diseases
M Gudowska-Sawczuk, A Wrona, E Gruszewska, B Cylwik, A Panasiuk, R Flisiak, L Chrostek |
Scandinavian Journal of Clinical & Laboratory Investigation | 2017 |
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Fibrose hépatique : Les myofibroblastes en question
C Housset |
Bulletin de l'Académie nationale de médecine | 2017 |
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Functional Immune Anatomy of the Liver-As an Allograft
AJ Demetris, CO Bellamy, CR Gandhi, S Prost, Y Nakanuma, DB Stolz |
American Journal of Transplantation | 2016 |
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Targeting Hepatic Fibrosis in Autoimmune Hepatitis
AJ Montano-Loza, RB Thandassery, AJ Czaja |
Digestive Diseases and Sciences | 2016 |
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Versican: a novel modulator of hepatic fibrosis
TN Bukong, SB Maurice, B Chahal, DF Schaeffer, PJ Winwood |
Laboratory Investigation | 2016 |
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The fibrosis-cell death axis in heart failure
A Piek, RA de Boer, HH Silljé |
Heart Failure Reviews | 2016 |
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Micronutrient Antioxidants and Nonalcoholic Fatty Liver Disease
G Chen, Y Ni, N Nagata, L Xu, T Ota |
International journal of molecular sciences | 2016 |
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Serum Amyloid A Induces Inflammation, Proliferation and Cell Death in Activated Hepatic Stellate Cells
SV Siegmund, M Schlosser, FA Schildberg, E Seki, SD Minicis, H Uchinami, C Kuntzen, PA Knolle, CP Strassburg, RF Schwabe, MA Avila |
PloS one | 2016 |
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Senescence in hepatic stellate cells as a mechanism of liver fibrosis reversal: a putative synergy between retinoic acid and PPAR-gamma signalings
C Panebianco, JA Oben, M Vinciguerra, V Pazienza |
Clinical and Experimental Medicine | 2016 |
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The characteristics of activated portal fibroblasts/myofibroblasts in liver fibrosis
D Karin, Y Koyama, D Brenner, T Kisseleva |
Differentiation | 2016 |
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Is Western Diet-Induced Nonalcoholic Steatohepatitis in Ldlr-/- Mice Reversible?
KA Lytle, DB Jump, H Guillou |
PloS one | 2016 |
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Knockdown of Astrocyte Elevated Gene-1 Inhibits Activation of Hepatic Stellate Cells
L Chen, Y Guo, A Li, J Ma, H Hao, D Zhang, Y Wang, C Ji, W Qi, J Wang, H Jiang |
Digestive Diseases and Sciences | 2016 |
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Remodeling of the Extracellular Matrix by Endothelial Cell-Targeting siRNA Improves the EPR-Based Delivery of 100 nm Particles
Y Sakurai, T Hada, S Yamamoto, A Kato, W Mizumura, H Harashima |
Molecular Therapy | 2016 |
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The unfolded protein response mediates fibrogenesis and collagen I secretion through regulating TANGO1 in mice: Maiers et al
JL Maiers, E Kostallari, M Mushref, TM deAssuncao, H Li, N Jalan-Sakrikar, RC Huebert, S Cao, H Malhi, VH Shah |
Hepatology | 2016 |
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Hepatic Stellate Cells and microRNAs in Pathogenesis of Liver Fibrosis
M Kitano, P Bloomston |
Journal of Clinical Medicine | 2016 |
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Deregulated neddylation in liver fibrosis: Zubiete-Franco et al
I Zubiete-Franco, P Fernández-Tussy, L Barbier-Torres, J Simon, D Fernández-Ramos, F Lopitz-Otsoa, VG Juan, SL de Davalillo, AM Duce, P Iruzubieta, D Taibo, J Crespo, J Caballeria, E Villa, I Aurrekoetxea, P Aspichueta, M Varela-Rey, SC Lu, JM Mato, N Beraza, TC Delgado, ML Martínez-Chantar |
Hepatology | 2016 |
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Characterization of hepatic stellate cells, portal fibroblasts, and mesothelial cells in normal and fibrotic livers
I Lua, Y Li, JA Zagory, KS Wang, SW French, J Sévigny, K Asahina |
Journal of Hepatology | 2016 |
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Co-delivery of small molecule hedgehog inhibitor and miRNA for treating liver fibrosis
V Kumar, G Mondal, R Dutta, RI Mahato |
Biomaterials | 2016 |
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Dihydroartemisinin prevents liver fibrosis in bile duct ligated rats by inducing hepatic stellate cell apoptosis through modulating the PI3K/Akt pathway: DHA Prevents Hepatic Fibrosis by Inducing HSC Apoptosis
Q Chen, L Chen, X Wu, F Zhang, H Jin, C Lu, J Shao, D Kong, L Wu, S Zheng |
IUBMB Life | 2016 |
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Mechanisms of platelet-mediated liver regeneration
T Lisman, RJ Porte |
Blood | 2016 |
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Role of NLRC5 in progression and reversal of hepatic fibrosis
X Liu, Y Wu, Y Yang, W Li, C Huang, X Meng, J Li |
Toxicology and Applied Pharmacology | 2016 |
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PTP1B confers liver fibrosis by regulating the activation of hepatic stellate cells
PJ Chen, SP Cai, Y Yang, WX Li, C Huang, XM Meng, J Li |
Toxicology and Applied Pharmacology | 2016 |
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Chebulic acid prevents hepatic fibrosis induced by advanced glycation end-products in LX-2 cell by modulating Nrf2 translocation via ERK pathway
YC Koo, MC Pyo, MH Nam, CO Hong, SY Yang, KW Lee |
Toxicology in Vitro | 2016 |
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TIMP-1 expression induced by IL-32 is mediated through activation of AP-1 signal pathway
H Xu, S Zhang, X Pan, H Cao, X Huang, Q Xu, H Zhong, X Peng |
International Immunopharmacology | 2016 |
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Virologic Cure of Hepatitis C: Impact on Hepatic Fibrosis and Patient Outcomes
HC Gonzalez, A Duarte-Rojo |
Current Gastroenterology Reports | 2016 |
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A new fluorescence-based optical imaging method to non-invasively monitor hepatic myofibroblasts in vivo
S Luli, DD Paolo, P Perri, C Brignole, SJ Hill, H Brown, J Leslie, HL Marshall, MC Wright, DA Mann, M Ponzoni, F Oakley |
Journal of Hepatology | 2016 |
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Smad2 increases the apoptosis of activated human hepatic stellate cells induced by TRAIL
F Xu, D Zhou, X Meng, X Wang, C Liu, C Huang, J Li, L Zhang |
International Immunopharmacology | 2016 |
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Hepatocellular carcinoma: Mouse models and the potential roles of proteases
JM Henderson, HE Zhang, N Polak, MD Gorrell |
Cancer Letters | 2016 |
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Homing in on the hepatic scar: recent advances in cell-specific targeting of liver fibrosis
R Dobie, NC Henderson |
F1000Research | 2016 |
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Matrix metalloproteinase-1 induction by diethyldithiocarbamate is regulated via Akt and ERK/miR222/ETS-1 pathways in hepatic stellate cells
T Liu, P Wang, M Cong, D Zhang, L Liu, H Li, Q Zhai, Z Li, J Jia, H You |
Bioscience Reports | 2016 |
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Liver Fibrosis Reversion After Suppression of Hepatitis B Virus
DC Rockey |
Clinics in Liver Disease | 2016 |
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Antifibrotics in chronic liver disease: tractable targets and translational challenges
P Ramachandran, NC Henderson |
The Lancet Gastroenterology & Hepatology | 2016 |
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Oxidative Stress and Hepatic Stellate Cells: A PARADOXICAL RELATIONSHIP
Chandrashekhar R. Gandhi |
Trends in cell & molecular biology | 2016 |
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Milk Fat Globule-EGF Factor 8, Secreted by Mesenchymal Stem Cells, Protects Against Liver Fibrosis in Mice
SY An, YJ Jang, HJ Lim, J Han, J Lee, G Lee, JY Park, SY Park, JH Kim, BR Do, C Han, HK Park, OH Kim, MJ Song, SJ Kim, JH Kim |
Gastroenterology | 2016 |
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The unfolded protein response mediates fibrogenesis and collagen I secretion through regulating TANGO1 in mice: Maiers et al
JL Maiers, E Kostallari, M Mushref, TM deAssuncao, H Li, N Jalan-Sakrikar, RC Huebert, S Cao, H Malhi, VH Shah |
Hepatology | 2016 |
|
Deregulated neddylation in liver fibrosis: Zubiete-Franco et al
I Zubiete-Franco, P Fernández-Tussy, L Barbier-Torres, J Simon, D Fernández-Ramos, F Lopitz-Otsoa, VG Juan, SL de Davalillo, AM Duce, P Iruzubieta, D Taibo, J Crespo, J Caballeria, E Villa, I Aurrekoetxea, P Aspichueta, M Varela-Rey, SC Lu, JM Mato, N Beraza, TC Delgado, ML Martínez-Chantar |
Hepatology | 2016 |
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Hepatic steatosis and fibrosis: Non-invasive assessment
RN Karanjia, MM Crossey, IJ Cox, HK Fye, R Njie, RD Goldin, SD Taylor-Robinson |
World journal of gastroenterology : WJG | 2016 |
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Aging enhances liver fibrotic response in mice through hampering extracellular matrix remodeling
B Delire, V Lebrun, C Selvais, P Henriet, A Bertrand, Y Horsmans, IA Leclercq |
Aging | 2016 |
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Remodeling of the Extracellular Matrix by Endothelial Cell-Targeting siRNA Improves the EPR-Based Delivery of 100 nm Particles
Y Sakurai, T Hada, S Yamamoto, A Kato, W Mizumura, H Harashima |
Molecular Therapy | 2016 |
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Anti-fibrotic effects of Cuscuta chinensis with in vitro hepatic stellate cells and a thioacetamide-induced experimental rat model
JS Kim, S Koppula, MJ Yum, GM Shin, YJ Chae, SM Hong, JD Lee, MD Song |
Pharmaceutical Biology | 2016 |
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Differential Roles of Angiogenesis in the Induction of Fibrogenesis and the Resolution of Fibrosis in Liver
S Park, JW Kim, JH Kim, CW Lim, B Kim |
Biological & Pharmaceutical Bulletin | 2015 |
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Animal Models for Fibrotic Liver Diseases: What We Have, What We Need, and What is Under Development
B Delire, P Starkel, I Leclercq |
Journal of Clinical and Translational Hepatology | 2015 |
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Inhibition of Cyclic Adenosine Monophosphate (cAMP)-response Element-binding Protein (CREB)-binding Protein (CBP)/β-Catenin Reduces Liver Fibrosis in Mice
Y Osawa, K Oboki, J Imamura, E Kojika, Y Hayashi, T Hishima, T Saibara, F Shibasaki, M Kohara, K Kimura |
EBioMedicine | 2015 |
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Reversibility of liver fibrosis
M Sun, T Kisseleva |
Clinics and Research in Hepatology and Gastroenterology | 2015 |
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Fibroblast growth factor 21 attenuates hepatic fibrogenesis through TGF-β/smad2/3 and NF-κB signaling pathways
P Xu, Y Zhang, Y Liu, Q Yuan, L Song, M Liu, Z Liu, Y Yang, J Li, D Li, G Ren |
Toxicology and Applied Pharmacology | 2015 |
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Reversibility and heritability of liver fibrosis: Implications for research and therapy
Hussein M Atta |
World journal of gastroenterology : WJG | 2015 |
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Study on the Antifibrotic Effects of Recombinant Shark Hepatical Stimulator Analogue (r-sHSA) in Vitro and in Vivo
Y Wang, X Zhang, Y Yang, X Yang, B Ye |
Marine drugs | 2015 |
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Silent information regulator 1 (SIRT1) ameliorates liver fibrosis via promoting activated stellate cell apoptosis and reversion
Y Wu, X Liu, Q Zhou, C Huang, X Meng, F Xu, J Li |
Toxicology and Applied Pharmacology | 2015 |
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Experimental models of liver fibrosis
SC Yanguas, B Cogliati, J Willebrords, M Maes, I Colle, B Bossche, CP de Oliveira, W Andraus, VA Alves, I Leclercq, M Vinken |
Archives of Toxicology | 2015 |
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Concise Review: Pluripotent Stem Cell-Derived Cardiac Cells, A Promising Cell Source for Therapy of Heart Failure: Where Do We Stand?: Pluripotent Stem Cells and Cardiac Cell Therapy
G Elodie, MM Thomas, SW Nicoline, C Lucienne, C Ruben, HE Sian, J Philippe, L Virginie, RM Catherine, P Michel |
Stem Cells | 2015 |
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Cardiac fibroblasts: from development to heart failure
T Moore-Morris, N Guimarães-Camboa, KE Yutzey, M Pucéat, SM Evans |
Journal of Molecular Medicine | 2015 |
|
Mechanisms of liver fibrosis resolution
F Tacke, C Trautwein |
Journal of Hepatology | 2015 |
|
CD248/endosialin critically regulates hepatic stellate cell proliferation during chronic liver injury via a PDGF-regulated mechanism
A Wilhelm, V Aldridge, D Haldar, AJ Naylor, CJ Weston, D Hedegaard, A Garg, J Fear, GM Reynolds, AP Croft, NC Henderson, CD Buckley, PN Newsome |
Gut | 2015 |
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Recent advancement of molecular mechanisms of liver fibrosis
E Seki, DA Brenner |
Journal of Hepato-Biliary-Pancreatic Sciences | 2015 |
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Human liver myofibroblasts during development and diseases with a focus on portal (myo)fibroblasts
Sà Lepreux, A Desmoulière |
Frontiers in physiology | 2015 |
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Morin, a dietary flavonoid, exhibits anti-fibrotic effect and induces apoptosis of activated hepatic stellate cells by suppressing canonical NF-κB signaling
P MadanKumar, P NaveenKumar, H Devaraj, S NiranjaliDevaraj |
Biochimie | 2015 |
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Adiponectin Reduces Hepatic Stellate Cell Migration by Promoting Tissue Inhibitor of Metalloproteinase-1 (TIMP-1) Secretion
M Ramezani-Moghadam, J Wang, V Ho, TJ Iseli, B Alzahrani, A Xu, D der Poorten, L Qiao, J George, L Hebbard |
The Journal of biological chemistry | 2015 |
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Sedum mexicanum Britt. Induces Apoptosis of Primary Rat Activated Hepatic Stellate Cells
SL Lee, TY Chin, CL Lai, WH Wang |
Evidence-Based Complementary and Alternative Medicine | 2015 |
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In vitro reversion of activated primary human hepatic stellate cells
AE Taghdouini, M Najimi, P Sancho-Bru, E Sokal, LA van Grunsven |
Fibrogenesis & Tissue Repair | 2015 |
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Cirrhosis: A practical guide to management
YY Yang, HC Lin |
Cirrhosis: A practical guide to management | 2015 |
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1,25-(OH)2-Vitamin D3 prevents activation of hepatic stellate cells in vitro and ameliorates inflammatory liver damage but not fibrosis in the Abcb4-/- model
FP Reiter, S Hohenester, JM Nagel, R Wimmer, R Artmann, L Wottke, MC Makeschin, D Mayr, C Rust, M Trauner, GU Denk |
Biochemical and Biophysical Research Communications | 2015 |
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Sustained Isoprostane E2 Elevation, Inflammation and Fibrosis after Acute Ischaemia-Reperfusion Injury Are Reduced by Pregnane X Receptor Activation
AO Amer, PM Probert, M Dunn, M Knight, AE Vallance, PA Flecknell, F Oakley, I Cameron, SA White, PG Blain, MC Wright, MA Avila |
PloS one | 2015 |
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Kinetin inhibits proliferation of hepatic stellate cells by interrupting cell cycle and induces apoptosis by down-regulating ratio of Bcl-2/Bax
Z Zhang, J Zou, Y Huang, L Wu |
Journal of Huazhong University of Science and Technology [Medical Sciences] | 2015 |
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Plasma levels of matrix metalloproteinase-2 and -9 in male and female patients with cirrhosis of different aetiologies
CY Huang, KC Tseng, MN Lin, JP Tsai, CC Su |
Journal of clinical pathology | 2015 |
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M1 Muscarinic Receptor Deficiency Attenuates Azoxymethane-Induced Chronic Liver Injury in Mice
V Rachakonda, RN Jadeja, NH Urrunaga, N Shah, D Ahmad, K Cheng, WS Twaddell, JP Raufman, S Khurana |
Scientific Reports | 2015 |
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Stellate Cells in Health and Disease
N Kawada, M Parola |
Stellate Cells in Health and Disease | 2015 |
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Protective effects of extracts from Pomegranate peels and seeds on liver fibrosis induced by carbon tetrachloride in rats
X Wei, R Fang, Y Yang, X Bi, G Ren, A Luo, M Zhao, W Zang |
BMC complementary and alternative medicine | 2015 |
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Antiviral therapy leads to histological improvement of HBeAg-negative chronic hepatitis B patients
Nikolaos Papachrysos, Prodromos Hytiroglou, Lavrentios Papalavrentios, Emmanouil Sinakos, Ioannis Kouvelis, Evangelos Akriviadis |
Annals of gastroenterology : quarterly publication of the Hellenic Society of Gastroenterology | 2015 |
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Transplantation of mesenchymal stem cells expressing TIMP-1-shRNA improves hepatic fibrosis in CCl4-treated rats
Yingwei Zhu, Zongning Miao, Lei Gong, Weichang Chen |
International journal of clinical and experimental pathology | 2015 |
|
Induction of experimental obstructive cholestasis in mice
CG Tag, S Weiskirchen, K Hittatiya, F Tacke, RH Tolba, R Weiskirchen |
Laboratory Animals | 2015 |
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Reversibility and heritability of liver fibrosis: Implications for research and therapy
HM Atta |
World journal of gastroenterology : WJG | 2015 |
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Yamada' s Textbook of Gastroenterology
DK Podolsky, M Camilleri, JG Fitz, AN Kalloo, F Shanahan, TC Wang |
Yamada' s Textbook of Gastroenterology | 2015 |
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Innovative Medicine
K Nakao, N Minato, S Uemoto |
2015 | |
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Resident fibroblast lineages mediate pressure overload-induced cardiac fibrosis
Thomas Moore-Morris, Nuno Guimarães-Camboa, Indroneal Banerjee, Alexander Zambon, Tatiana Kisseleva, Aurelie Velayoudon, William B. Stallcup, Yusu Gu, Nancy Dalton, Martha Cedenilla, Rafael Gomez-Amaro, Bin Zhou, David A. Brenner, Kirk Peterson, Ju Chen, Sylvia Evans |
Journal of Clinical Investigation | 2014 |
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Cell Death and Cell Death Responses in Liver Disease: Mechanisms and Clinical Relevance
T Luedde, N Kaplowitz, RF Schwabe |
Gastroenterology | 2014 |
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Potential approaches to reverse or repair renal fibrosis
D Tampe, M Zeisberg |
Nature Reviews Nephrology | 2014 |
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Bone Marrow–Derived Stromal Cell Therapy in Cirrhosis: Clinical Evidence, Cellular Mechanisms, and Implications for the Treatment of Hepatocellular Carcinoma
JM Vainshtein, R Kabarriti, KJ Mehta, J Roy-Chowdhury, C Guha |
International journal of radiation oncology, biology, physics | 2014 |
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New Approaches for Studying Alcoholic Liver Disease
J Xu, X Liu, B Gao, M Karin, H Tsukamoto, D Brenner, T Kisseleva |
Current Pathobiology Reports | 2014 |
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Hepatic inflammation and progressive liver fibrosis in chronic liver disease
AJ Czaja |
World journal of gastroenterology : WJG | 2014 |
|
The types of hepatic myofibroblasts contributing to liver fibrosis of different etiologies
J Xu, X Liu, Y Koyama, P Wang, T Lan, IG Kim, IH Kim, HY Ma, T Kisseleva |
Frontiers in pharmacology | 2014 |
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Vascular Endothelial Growth Factor Promotes Fibrosis Resolution and Repair in Mice
L Yang, J Kwon, Y Popov, GB Gajdos, T Ordog, RA Brekken, D Mukhopadhyay, D Schuppan, Y Bi, D Simonetto, VH Shah |
Gastroenterology | 2014 |
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Resolution of liver fibrosis requires myeloid cell-driven sinusoidal angiogenesis
C Kantari-Mimoun, M Castells, R Klose, AK Meinecke, UJ Lemberger, PE Rautou, H Pinot-Roussel, C Badoual, K Schrödter, CH Österreicher, J Fandrey, C Stockmann |
2014 | |
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Future Directions in Idiopathic Pulmonary Fibrosis Research. An NHLBI Workshop Report
TS Blackwell, AM Tager, Z Borok, BB Moore, DA Schwartz, KJ Anstrom, Z Bar-Joseph, P Bitterman, MR Blackburn, W Bradford, KK Brown, HA Chapman, HR Collard, GP Cosgrove, R Deterding, R Doyle, KR Flaherty, CK Garcia, JS Hagood, CA Henke, E Herzog, CM Hogaboam, JC Horowitz, TE King, JE Loyd, WE Lawson, CB Marsh, PW Noble, I Noth, D Sheppard, J Olsson, LA Ortiz, TG O’Riordan, TD Oury, G Raghu, J Roman, PJ Sime, TH Sisson, D Tschumperlin, SM Violette, TE Weaver, RG Wells, ES White, N Kaminski, FJ Martinez, TA Wynn, VJ Thannickal, JP Eu |
American journal of respiratory and critical care medicine | 2014 |
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Liver fibrosis and repair: immune regulation of wound healing in a solid organ
A Pellicoro, P Ramachandran, JP Iredale, JA Fallowfield |
Nature Reviews Immunology | 2014 |
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Matrix Biology of Idiopathic Pulmonary Fibrosis
VJ Thannickal, CA Henke, JC Horowitz, PW Noble, J Roman, PJ Sime, Y Zhou, RG Wells, ES White, DJ Tschumperlin |
The American Journal of Pathology | 2014 |
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Molecular Mechanism and Treatment of Viral Hepatitis-Related Liver Fibrosis
TH Su, JH Kao, CJ Liu |
International journal of molecular sciences | 2014 |
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Preparing the ground for tissue regeneration: from mechanism to therapy
SJ Forbes, N Rosenthal |
Nature Medicine | 2014 |
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Mistletoe alkaloid fractions alleviates carbon tetrachloride-induced liver fibrosis through inhibition of hepatic stellate cell activation via TGF-β/Smad interference
Y Jiang, C Wang, YY Li, XC Wang, JD An, YJ Wang, XJ Wang |
2014 | |
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Mutant MMP-9 and HGF Gene Transfer Enhance Resolution of CCl4-Induced Liver Fibrosis in Rats: Role of ASH1 and EZH2 Methyltransferases Repression
H Atta, M El-Rehany, O Hammam, H Abdel-Ghany, M Ramzy, M Roderfeld, E Roeb, A Al-Hendy, SA Raheim, H Allam, H Marey, MA Avila |
2014 | |
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Reversal, maintenance or progression: What happens to the liver after a virologic cure of hepatitis C?
YA Lee, SL Friedman |
Antiviral Research | 2014 |
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Fibrogenesis and Carcinogenesis in Nonalcoholic Steatohepatitis (NASH): Involvement of Matrix Metalloproteinases (MMPs) and Tissue Inhibitors of Metalloproteinase (TIMPs)
I Okazaki, T Noro, N Tsutsui, E Yamanouchi, H Kuroda, M Nakano, H Yokomori, Y Inagaki |
Cancers | 2014 |
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Activated Hepatic Stellate Cells Are Dependent on Self-collagen, Cleaved by Membrane Type 1 Matrix Metalloproteinase for Their Growth
NK Birukawa, K Murase, Y Sato, A Kosaka, A Yoneda, H Nishita, R Fujita, M Nishimura, T Ninomiya, K Kajiwara, M Miyazaki, Y Nakashima, S Ota, Y Murakami, Y Tanaka, K Minomi, Y Tamura, Y Niitsu |
The Journal of biological chemistry | 2014 |
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Platelet-derived Growth Factor Primes Cancer-associated Fibroblasts for Apoptosis
S Rizvi, JC Mertens, SF Bronk, P Hirsova, H Dai, LR Roberts, SH Kaufmann, GJ Gores |
The Journal of biological chemistry | 2014 |
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Alcohol Disrupts Human Liver Stem/Progenitor Cell Proliferation and Differentiation
X Shi |
Journal of Stem Cell Research & Therapy | 2014 |
|
Activation of adenosine receptor A2A increases HSC proliferation and inhibits death and senescence by down-regulation of p53 and Rb
MK Ahsan, WZ Mehal |
Frontiers in pharmacology | 2014 |
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Diallyl trisulfide attenuates carbon tetrachloride-caused liver injury and fibrogenesis and reduces hepatic oxidative stress in rats
X Zhu, F Zhang, L Zhou, D Kong, L Chen, Y Lu, SZ Zheng |
Naunyn-Schmiedeberg's Archives of Pharmacology | 2014 |
|
Comprehensive Physiology
SN Cheuvront, RW Kenefick |
Comprehensive Physiology | 2014 |
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Myofibroblast Differentiation: Main Features, Biomedical Relevance, and the Role of Reactive Oxygen Species
A Siani, N Tirelli |
Antioxidants & Redox Signaling | 2014 |
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Review article: the prevention and reversal of hepatic fibrosis in autoimmune hepatitis
AJ Czaja |
Alimentary Pharmacology & Therapeutics | 2014 |
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Hepatic stellate cells and extracellular matrix in hepatocellular carcinoma: more complicated than ever
V Carloni, TV Luong, K Rombouts |
Liver International | 2014 |
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Inhibition of a novel fibrogenic factor Tl1a reverses established colonic fibrosis
DQ Shih, L Zheng, X Zhang, H Zhang, Y Kanazawa, R Ichikawa, KL Wallace, J Chen, C Pothoulakis, HW Koon, SR Targan |
Mucosal Immunology | 2014 |
|
Role of Endocannabinoid Activation of Peripheral CB1 Receptors in the Regulation of Autoimmune Disease
JM Sido, PS Nagarkatti, M Nagarkatti |
International Reviews of Immunology | 2014 |
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Mouse Models of Liver Fibrosis Mimic Human Liver Fibrosis of Different Etiologies
AK Martínez, L Maroni, M Marzioni, ST Ahmed, M Milad, D Ray, G Alpini, SS Glaser |
2014 | |
|
Resolution of chronic bacterial-induced prostatic inflammation reverses established fibrosis: Reversibility of Prostatic Fibrosis
L Wong, PR Hutson, W Bushman |
2014 | |
|
Liver Fibrosis and Protection Mechanisms Action of Medicinal Plants Targeting Apoptosis of Hepatocytes and Hepatic Stellate Cells
F Duval, JE Moreno-Cuevas, MT González-Garza, C Rodríguez-Montalvo, DE Cruz-Vega |
2014 | |
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Nitric oxide is a potential mediator of hepatic inflammation and fibrogenesis in autoimmune hepatitis
Y Beyazit, C Efe, A Tanoglu, T Purnak, A Sayilir, I Taskıran, M Kekilli, T Turhan, E Ozaslan, S Wahlin |
2014 | |
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Protective Effects of Selenium-Enriched Probiotics on Carbon Tetrachloride-Induced Liver Fibrosis in Rats
Y Liu, Q Liu, G Ye, A Khan, J Liu, F Gan, X Zhang, S Kumbhar, K Huang |
2014 | |
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The influence of astragalus polysaccharide and β-elemene on LX-2 cell growth, apoptosis and activation
J Zheng, L Ma, Q Ren, L Li, Y Zhang, H Shi, Y Liu, C Li, Y Dou, S Li, H Zhang, M Yang |
2014 | |
|
Reversibility of hepatitis B virus cirrhosis after therapy: who and why?
P Bedossa |
2014 | |
|
Role of Bone Marrow Mesenchymal Stem Cells in the Treatment of CCL 4 Induced Liver Fibrosis in Albino Rats: A Histological and Immunohistochemical Study
SK Ahmed, SA Mohammed, G Khalaf, H Fikry |
2014 | |
|
Determination of DNA Damage in Experimental Liver Intoxication and Role of N-Acetyl Cysteine
H Aksit, A Bildik |
Cell Biochemistry and Biophysics | 2014 |
|
Decursin attenuates hepatic fibrogenesis through interrupting TGF-beta-mediated NAD(P)H oxidase activation and Smad signaling in vivo and in vitro
YJ Choi, DH Kim, SJ Kim, J Kim, SI Jeong, CH Chung, KY Yu, SY Kim |
Life Sciences | 2014 |
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Early Detection of Liver Fibrosis in Rats Using 3-D Ultrasound Nakagami Imaging: A Feasibility Evaluation
MC Ho, PH Tsui, YH Lee, YS Chen, CN Chen, JJ Lin, CC Chang |
Ultrasound in Medicine & Biology | 2014 |
|
Anti-fibrotic effect of PF2401-SF, a standardized fraction of Salvia miltiorrhiza, in thioacetamide-induced experimental rats liver fibrosis
DR Parajuli, YZ Zhao, H Jin, JH Chi, SY Li, YC Kim, DH Sohn, SH Lee |
Archives of Pharmacal Research | 2014 |
|
Does hepatic vagus nerve modulate the progression of biliary fibrosis in rats?
K Hajiasgharzadeh, SM Tavangar, M Javan, AR Dehpour, AR Mani |
Autonomic Neuroscience | 2014 |
|
Pathobiology of Human Disease
S Akilesh |
Pathobiology of Human Disease | 2014 |
|
Extracellular Matrix Metabolism and Fibrotic Disease
L Campana, JP Iredale |
2014 | |
|
Reference Module in Biomedical Sciences
DL Sackett, RB Haynes |
2014 | |
|
A Glimpse of Matrix Metalloproteinases in Diabetic Nephropathy
X. Xu, L. Xiao, P. Xiao, S. Yang, G. Chen, F. Liu, Y.Y. Kanwar, L. Sun |
Current medicinal chemistry | 2014 |
|
Antifibrotic effects of luteolin on hepatic stellate cells and liver fibrosis by targeting AKT/mTOR/p70S6K and TGFβ/Smad signalling pathways
J Li, X Li, W Xu, S Wang, Z Hu, Q Zhang, X Deng, J Wang, J Zhang, C Guo |
Liver International | 2014 |
|
Mechanosensitive Signaling in Myofibroblasts as a Target for Anti-Fibrotic Therapy
Yong Zhou, Xiangwei Huang, Louise Hecker, Deepali Kurundkar, Ashish Kurundkar, Hui Liu, Tonghuan Jin, Leena Desai, Karen Bernard, Victor J. Thannickal |
Journal of Clinical Investigation | 2013 |
|
RNA interference against discoidin domain receptor 2 ameliorates alcoholic liver disease in rats
Z Luo, H Liu, X Sun, R Guo, R Cui, X Ma, M Yan |
PloS one | 2013 |
|
Therapy for Fibrotic Diseases: Nearing the Starting Line
SL Friedman, D Sheppard, JS Duffield, S Violette |
Science Translational Medicine | 2013 |
|
Translating an Understanding of the Pathogenesis of Hepatic Fibrosis to Novel Therapies
DC Rockey |
Clinical Gastroenterology and Hepatology | 2013 |
|
Hepatic macrophages but not dendritic cells contribute to liver fibrosis by promoting the survival of activated hepatic stellate cells in mice: Hepatology, Vol. 57, No. X, 2013
JP Pradere, J Kluwe, SD Minicis, JJ Jiao, GY Gwak, DH Dapito, MK Jang, ND Guenther, I Mederacke, R Friedman, AC Dragomir, C Aloman, RF Schwabe |
Hepatology | 2013 |
|
Reversibility of Liver Fibrosis and Inactivation of Fibrogenic Myofibroblasts
X Liu, J Xu, DA Brenner, T Kisseleva |
Current Pathobiology Reports | 2013 |
|
Experimental liver fibrosis research: update on animal models, legal issues and translational aspects
C Liedtke, T Luedde, T Sauerbruch, D Scholten, K Streetz, F Tacke, R Tolba, C Trautwein, J Trebicka, R Weiskirchen |
Fibrogenesis & Tissue Repair | 2013 |
|
Up-regulation of RACK1 by TGF-β1 promotes hepatic fibrosis in mice
D Jia, F Duan, P Peng, L Sun, X Liu, L Wang, W Wu, Y Ruan, J Gu |
PloS one | 2013 |
|
Absence of Nogo-B (Reticulon 4B) Facilitates Hepatic Stellate Cell Apoptosis and Diminishes Hepatic Fibrosis in Mice
K Tashiro, A Satoh, T Utsumi, C Chung, Y Iwakiri |
The American Journal of Pathology | 2013 |
|
γ-Aminobutyric Acid B Receptor Improves Carbon Tetrachloride-Induced Liver Fibrosis in Rats
W Fan, B Shi, H Wei, X Ma, X He, K Feng |
Digestive Diseases and Sciences | 2013 |
|
Inhibition of RelA-Ser536 Phosphorylation by a Competing Peptide Reduces Mouse Liver Fibrosis Without Blocking The Innate Immune Response
A Moles, AM Sanchez, PS Banks, LB Murphy, S Luli, L Borthwick, A Fisher, S O'Reilly, JM van Laar, SA White, ND Perkins, AD Burt, DA Mann, F Oakley |
Hepatology | 2013 |
|
1,25-dihydroxyvitamin D3 and its nuclear receptor repress human α 1 (I) collagen expression and type I collagen formation
JJ Potter, X Liu, A Koteish, E Mezey |
Liver International | 2013 |
|
miR-200b inhibits TGF-β1-induced epithelial-mesenchymal transition and promotes growth of intestinal epithelial cells
Y Chen, Y Xiao, W Ge, K Zhou, J Wen, W Yan, Y Wang, B Wang, C Qu, J Wu, L Xu, W Cai |
Cell Death and Disease | 2013 |
|
Effect of the protease inhibitor MG132 on the transforming growth factor-β/Smad signaling pathway in HSC-T6 cells
Z Ren, L Sun, Y Xia, Q Tong |
Journal of Huazhong University of Science and Technology [Medical Sciences] | 2013 |
|
Inactivation of myofibroblasts during regression of liver fibrosis
T Kisseleva, DA Brenner |
Cell cycle (Georgetown, Tex.) | 2013 |
|
S-nitroso-N-acetylcysteine attenuates liver fibrosis in experimental nonalcoholic steatohepatitis
DF Mazo, MG de Oliveira, IV Pereira, B Cogliati, JT Stefano, GF de Souza, F Rabelo, FR Lima, VA Alves, FJ Carrilho, CP de Oliveira |
Drug design, development and therapy | 2013 |
|
Telmisartan, an AT1 receptor blocker and a PPAR gamma activator, alleviates liver fibrosis induced experimentally by Schistosoma mansoni infection
YM Attia, EF Elalkamy, OA Hammam, SS Mahmoud, AS El-Khatib |
Parasites & vectors | 2013 |
|
Origins and functions of liver myofibroblasts
S Lemoinne, A Cadoret, HE Mourabit, D Thabut, C Housset |
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease | 2013 |
|
Persistent fibrosis in the liver of choline-deficient and iron-supplemented l-amino acid-defined diet-induced nonalcoholic steatohepatitis rat due to continuing oxidative stress after choline supplementation
A Takeuchi-Yorimoto, T Noto, A Yamada, Y Miyamae, Y Oishi, M Matsumoto |
Toxicology and Applied Pharmacology | 2013 |
|
Hepatic apoptosis can modulate liver fibrosis through TIMP1 pathway
K Wang, B Lin, JJ Brems, RL Gamelli |
Apoptosis | 2013 |
|
Antifibrotic Effects of a Recombinant Adeno-Associated Virus Carrying Small Interfering RNA Targeting TIMP-1 in Rat Liver Fibrosis
M Cong, T Liu, P Wang, X Fan, A Yang, Y Bai, Z Peng, P Wu, X Tong, J Chen, H Li, R Cong, S Tang, B Wang, J Jia, H You |
The American Journal of Pathology | 2013 |
|
Cell-specific delivery of biologicals: problems, pitfalls and possibilities of antifibrotic compounds in the liver
K Poelstra, L Beljaars, BN Melgert |
Drug Discovery Today | 2013 |
|
Cirrhosis Regression and Subclassification
P Bedossa, G Garcia-Tsao, D Jain |
Surgical Pathology Clinics | 2013 |
|
Reversion of hepatic stellate cell to a quiescent phenotype: From myth to reality?
A Mallat, S Lotersztajn |
Journal of Hepatology | 2013 |
|
Modulation of extracellular matrix proteins and hepatate stellate cell activation following gadolinium chloride induced Kuffer cell blockade in an experimental model of liver fibrosis/cirrhosis
N Tekkesin, Y Taga, A Sav, S Bozkurt |
QScience Connect | 2013 |
|
Animal Models for the Study of Human Disease
HA Lawson |
Animal Models for the Study of Human Disease | 2013 |
|
Characterization of glial fibrillary acidic protein (GFAP)-expressing hepatic stellate cells and myofibroblasts in thioacetamide (TAA)-induced rat liver injury
AH Tennakoon, T Izawa, KK Wijesundera, HM Golbar, M Tanaka, C Ichikawa, M Kuwamura, J Yamate |
Experimental and Toxicologic Pathology | 2013 |
|
Lysophosphatidic acid (LPA) signaling through LPA1 in organ fibrosis: A pathway with pleiotropic pro-fibrotic effects
N Sakai, AM Tager |
Inflammation and Regeneration | 2013 |
|
Effects of compound traditional Astragalus and Salvia Miltiorrhiza extract on acute and chronic hepatic injury
X Zhang, Y Yang, X Liu, C Wu, M Chen |
TANG | 2013 |
|
Guggulsterone attenuates activation and survival of hepatic stellate cell by inhibiting nuclear factor kappa B activation and inducing apoptosis: Guggulsterone in liver fibrosis
BH Kim, JH Yoon, JI Yang, SJ Myung, JH Lee, EU Jung, SJ Yu, YJ Kim, HS Lee, CY Kim |
Journal of Gastroenterology and Hepatology | 2013 |
|
RNA Interference against Discoidin Domain Receptor 2 Ameliorates Alcoholic Liver Disease in Rats
Z Luo, H Liu, X Sun, R Guo, R Cui, X Ma, M Yan, P Mukhopadhyay |
PloS one | 2013 |
|
Up-Regulation of RACK1 by TGF-β1 Promotes Hepatic Fibrosis in Mice
D Jia, F Duan, P Peng, L Sun, X Liu, L Wang, W Wu, Y Ruan, J Gu, A Alisi |
PloS one | 2013 |
|
Cellular Mechanisms of Tissue Fibrosis. 5. Novel insights into liver fibrosis
A Mallat, S Lotersztajn |
American journal of physiology. Cell physiology | 2013 |
|
Metallothionein Gene Transfection Reverses the Phenotype of Activated Human Hepatic Stellate Cells
X Xu, F Shi, W Huang, YJ Kang |
The Journal of pharmacology and experimental therapeutics | 2013 |
|
Treatment of pancreatic fibrosis with siRNA against a collagen-specific chaperone in vitamin A-coupled liposomes
H Ishiwatari, Y Sato, K Murase, A Yoneda, R Fujita, H Nishita, NK Birukawa, T Hayashi, T Sato, K Miyanishi, R Takimoto, M Kobune, S Ota, Y Kimura, K Hirata, J Kato, Y Niitsu |
Gut | 2012 |
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Animal models of chronic liver diseases
Y Liu, C Meyer, C Xu, H Weng, C Hellerbrand, P Dijke, S Dooley |
AJP Gastrointestinal and Liver Physiology | 2012 |
|
Alcoholic liver disease and the potential role of plasminogen activator inhibitor-1 and fibrin metabolism
JI Beier, GE Arteel |
Experimental biology and medicine (Maywood, N.J.) | 2012 |
|
Tissue Microenvironments Define and Get Reinforced by Macrophage Phenotypes in Homeostasis or during Inflammation, Repair and Fibrosis
M Weidenbusch, HJ Anders |
Journal of Innate Immunity | 2012 |
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Tissues use resident dendritic cells and macrophages to maintain homeostasis and to regain homeostasis upon tissue injury: the immunoregulatory role of changing tissue environments
M Lech, R Gröbmayr, M Weidenbusch, HJ Anders |
Mediators of Inflammation | 2012 |
|
Reversibility of liver fibrosis
A Pellicoro, P Ramachandran, JP Iredale |
Fibrogenesis & Tissue Repair | 2012 |
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Elastin accumulation is regulated at the level of degradation by macrophage metalloelastase (MMP-12) during experimental liver fibrosis
A Pellicoro, RL Aucott, P Ramachandran, AJ Robson, JA Fallowfield, VK Snowdon, SN Hartland, M Vernon, JS Duffield, RC Benyon, SJ Forbes, JP Iredale |
Hepatology | 2012 |
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Mechanisms and Biomarkers of Apoptosis in Liver Disease and Fibrosis
JB Chakraborty, F Oakley, MJ Walsh |
International Journal of Hepatology | 2012 |
|
Liver fibrosis: a bidirectional model of fibrogenesis and resolution
P Ramachandran, JP Iredale |
QJM | 2012 |
|
The Crucial Role of Cholangiocytes in Cholangiopathies
SM Park |
Gut and Liver | 2012 |
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Therapeutic effects of deleting cancer-associated fibroblasts in cholangiocarcinoma
JC Mertens, CD Fingas, JD Christensen, RL Smoot, SF Bronk, NW Werneburg, MP Gustafson, AB Dietz, LR Roberts, AE Sirica, GJ Gores |
Cancer research | 2012 |
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MR T1ρ as an imaging biomarker for monitoring liver injury progression and regression: an experimental study in rats with carbon tetrachloride intoxication
F Zhao, YX Wang, J Yuan, M Deng, HL Wong, ES Chu, MY Go, GJ Teng, AT Ahuja, J Yu |
European Radiology | 2012 |
|
Fibrogenic cell reversion underlies fibrosis regression in liver
SL Friedman |
Proceedings of the National Academy of Sciences | 2012 |
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Acid sphingomyelinase deficiency contributes to resistance of scleroderma fibroblasts to Fas-mediated apoptosis
GH Samuel, S Lenna, AM Bujor, R Lafyatis, M Trojanowska |
Journal of Dermatological Science | 2012 |
|
Deactivation of Hepatic Stellate Cells During Liver Fibrosis Resolution in Mice
JS Troeger, I Mederacke, GY Gwak, DH Dapito, X Mu, CC Hsu, JP Pradere, RA Friedman, RF Schwabe |
Gastroenterology | 2012 |
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The microenvironment in hepatocyte regeneration and function in rats with advanced cirrhosis
L Liu, GR Yannam, T Nishikawa, T Yamamoto, H Basma, R Ito, M Nagaya, J Dutta-Moscato, DB Stolz, F Duan, KH Kaestner, Y Vodovotz, A Soto-Gutierrez, IJ Fox |
Hepatology | 2012 |
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Cyclin E1 controls proliferation of hepatic stellate cells and is essential for liver fibrogenesis in mice
YA Nevzorova, JM Bangen, W Hu, U Haas, R Weiskirchen, N Gassler, S Huss, F Tacke, P Sicinski, C Trautwein, C Liedtke |
Hepatology | 2012 |
|
Understanding the Mechanism of Hepatic Fibrosis and Potential Therapeutic Approaches
A Ahmad, R Ahmad |
Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association | 2012 |
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Parthenolide-induced apoptosis of hepatic stellate cells and anti-fibrotic effects in an in vivo rat model
IH Kim, SW Kim, SH Kim, SO Lee, ST Lee, DG Kim, MJ Lee, WH Park |
Experimental & molecular medicine | 2012 |
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Intravenous injection of mesenchymal stem cells is effective in treating liver fibrosis
W Zhao, JJ Li, DY Cao, X Li, LY Zhang, Y He, SQ Yue, DS Wang, KF Dou |
World journal of gastroenterology : WJG | 2012 |
|
Myofibroblasts revert to an inactive phenotype during regression of liver fibrosis
T Kisseleva, M Cong, Y Paik, D Scholten, C Jiang, C Benner, K Iwaisako, T Moore-Morris, B Scott, H Tsukamoto, SM Evans, W Dillmann, CK Glass, DA Brenner |
Proceedings of the National Academy of Sciences | 2012 |
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N-Terminal Region of Gelsolin Induces Apoptosis of Activated Hepatic Stellate Cells by a Caspase-Dependent Mechanism
B Mazumdar, K Meyer, R Ray |
PloS one | 2012 |
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Vascular disorders
IR Wanless, WY Huang |
MacSween s Pathology of the Liver | 2012 |
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Tissue-specific differences in inflammatory infiltrate and matrix metalloproteinase expression in adipose tissue and liver of mice with diet-induced obesity : MMP expression in obesity and fatty liver
VE de Meijer, DY Sverdlov, HD Le, Y Popov, M Puder |
Hepatology Research | 2012 |
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Mechanisms of Liver Cell Destruction
H Malhi |
Zakim and Boyer s Hepatology | 2012 |
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Hepatic Fibrosis and Cirrhosis
DC Rockey, SL Friedman |
Zakim and Boyer s Hepatology | 2012 |
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Combining semiquantitative measures of fibrosis and qualitative features of parenchymal remodelling to identify fibrosis regression in hepatitis C: a multiple biopsy study : HCV fibrosis regression biopsy study
V Pattullo, HH Thein, EJ Heathcote, M Guindi |
Histopathology | 2012 |
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Stem Cell Therapy in the Context of Chronic Liver Disease : Promise and Pitfalls
P Ramachandran, J Iredale |
Regenerative Medicine Stem Cells and the Liver | 2012 |
|
MacSween's Pathology of the Liver
RJ Thompson, BC Portmann, EA Roberts |
MacSween's Pathology of the Liver | 2012 |
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PEGylation of interleukin-10 improves the pharmacokinetic profile and enhances the antifibrotic effectivity in CCl4-induced fibrogenesis in mice
A Mattos, A Jager-Krikken, M Haan, L Beljaars, K Poelstra |
Journal of Controlled Release | 2012 |
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Standing Down the Guard: Stellate Cells Leave Quietly
NC Henderson, JP Iredale |
Gastroenterology | 2012 |
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Endoplasmic Reticulum stress induces hepatic stellate cell apoptosis and contributes to fibrosis resolution
S Minicis, C Candelaresi, L Agostinelli, S Taffetani, S Saccomanno, C Rychlicki, L Trozzi, M Marzioni, A Benedetti, G Svegliati-Baroni |
Liver International | 2012 |
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S-adenosylmethionine (SAMe) therapy in liver disease: A review of current evidence and clinical utility
QM Anstee, CP Day |
Journal of Hepatology | 2012 |
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Blumgart's Surgery of the Liver, Pancreas and Biliary Tract
CV Cott, R Zuckerman, WS Helton |
Blumgart's Surgery of the Liver, Pancreas and Biliary Tract | 2012 |
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Role of sphingosine 1-phosphate and lysophosphatidic acid in fibrosis
NJ Pyne, G Dubois, S Pyne |
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids | 2012 |
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Antifibrotic effects of glycyrrhizin and matrine in vitro and in vivo
J Zhao, X Wan, M Luo, T Chen, P He |
Biomedicine & Preventive Nutrition | 2012 |
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Garlic extract attenuating rat liver fibrosis by inhibiting TGF-β1
G D’Argenio, G Mazzone, MT Ribecco, V Lembo, P Vitaglione, M Guarino, F Morisco, M Napolitano, V Fogliano, N Caporaso |
Clinical Nutrition | 2012 |
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Activated hepatic stellate cells mediate the differentiation of macrophages: Activated HSC-mediated macrophage differentiation
J Chang, T Hisamatsu, K Shimamura, K Yoneno, M Adachi, H Naruse, T Igarashi, H Higuchi, K Matsuoka, MT Kitazume, S Ando, N Kamada, T Kanai, T Hibi |
Hepatology Research | 2012 |
|
Autotaxin in liver fibrosis
H Ikeda, Y Yatomi |
Clinica chimica acta; international journal of clinical chemistry | 2012 |
|
Antifibrotic Activity of Sorafenib in Experimental Hepatic Fibrosis: Refinement of Inhibitory Targets, Dosing, and Window of Efficacy In Vivo
F Hong, H Chou, MI Fiel, SL Friedman |
Digestive Diseases and Sciences | 2012 |
|
Hepatic stellate cells promote immunotolerance following orthotopic liver transplantation in rats via induction of T cell apoptosis and regulation of Th2/Th3-like cell cytokine production
Z Jiang, Y Chen, X Feng, J Jiang, T Chen, H Xie, L Zhou, S Zheng |
Experimental and therapeutic medicine | 2012 |
|
Phosphodiesterase inhibition mediates matrix metalloproteinase activity and the level of collagen degradation fragments in a liver fibrosis ex vivo rat model
SS Veidal, MJ Nielsen, DJ Leeming, MA Karsdal |
BMC Research Notes | 2012 |
|
Antifibrotic Activity of Diarylheptanoids from Betula platyphylla toward HSC-T6 Cells
M LEE, JH PARK, DS MIN, H YOO, JH PARK, YC KIM, SH SUNG |
Bioscience Biotechnology and Biochemistry | 2012 |
|
Wavelet Transform for Detection of Conserved Motifs inProtein Sequences with Ten Bit Physico-ChemicalProperties
J Meher |
International Journal of Information and Electronics Engineering | 2012 |
|
Amelioration of Murine Schistosoma mansoni Induced Liver Fibrosis by Mesenchymal Stem Cells
AA Mt, A Hm, R Nk, R LA, S D, H Aa, AF Gi, H Nm, Y Rh, Chowdhury |
Journal of stem cells & regenerative medicine | 2012 |
|
Evaluation of the spontaneous reversibility of carbon tetrachloride-induced liver cirrhosis in rabbits
E Bravo, E D'Amore, F Ciaffoni, CL Mammola |
Laboratory Animals | 2012 |
|
Regenerative Medicine and Cell Therapy
H Baharvand, N Aghdami |
2012 | |
|
Anti-fibrogenic Strategies and the regression of fibrosis
T Kisseleva, DA Brenner |
Best practice & research. Clinical gastroenterology | 2011 |
|
The role of the renin–angiotensin system in liver fibrosis
MK Munshi, MN Uddin, SS Glaser |
Experimental biology and medicine (Maywood, N.J.) | 2011 |
|
The phenotypic fate and functional role for bone marrow-derived stem cells in liver fibrosis
T Kisseleva, DA Brenner |
Journal of Hepatology | 2011 |
|
NF-κB in the liver—linking injury, fibrosis and hepatocellular carcinoma
T Luedde, RF Schwabe |
Nature Reviews Gastroenterology & Hepatology | 2011 |
|
Liver fibrosis: mechanisms of immune-mediated liver injury
R Xu, Z Zhang, FS Wang |
Cellular and Molecular Immunology | 2011 |
|
Dendritic cell regulation of carbon tetrachloride-induced murine liver fibrosis regression
J Jiao, D Sastre, MI Fiel, UE Lee, Z Ghiassi-Nejad, F Ginhoux, E Vivier, SL Friedman, M Merad, C Aloman |
Hepatology | 2011 |
|
Reversal of hepatic fibrosis: pathophysiological basis of antifibrotic therapies
MH Ismail, M Pinzani |
Hepatic medicine : evidence and research | 2011 |
|
Ineffective CD8(+) T-cell immunity to adeno-associated virus can result in prolonged liver injury and fibrogenesis
J Spahn, RH Pierce, IN Crispe |
The American Journal of Pathology | 2011 |
|
Pathogenesis and treatment of hepatic fibrosis: is cirrhosis reversible?
Fallowfield J, Hayes P |
Clinical Medicine | 2011 |
|
Sherlock's Diseases of the Liver and Biliary System
AS Lok |
Sherlock's Diseases of the Liver and Biliary System | 2011 |
|
Animal models for the study of hepatic fibrosis
P Starkel, IA Leclercq |
Best Practice & Research Clinical Gastroenterology | 2011 |
|
Silencing tissue inhibitors of metalloproteinases (TIMPs) with short interfering RNA reveals a role for TIMP-1 in hepatic stellate cell proliferation
AJ Fowell, JE Collins, DR Duncombe, JA Pickering, WM Rosenberg, RC Benyon |
Biochemical and Biophysical Research Communications | 2011 |
|
The use of low molecular weight heparin–pluronic nanogels to impede liver fibrosis by inhibition the TGF-β/Smad signaling pathway
JH Lee, H Lee, YK Joung, KH Jung, JH Choi, DH Lee, KD Park, SS Hong |
Biomaterials | 2011 |
|
Macrophage therapy for murine liver fibrosis recruits host effector cells improving fibrosis, regeneration, and function
JA Thomas, C Pope, D Wojtacha, AJ Robson, TT Gordon-Walker, S Hartland, P Ramachandran, MV Deemter, DA Hume, JP Iredale, SJ Forbes |
Hepatology | 2011 |
|
Myofibroblasts and colonic anastomosis healing in Wistar rats
C Kosmidis, C Efthimiadis, G Anthimidis, G Basdanis, S Apostolidis, P Hytiroglou, K Vasiliadou, J Prousalidis, E Fahantidis |
BMC surgery | 2011 |
|
Models and Mechanisms of Fibrosis Resolution
VK Snowdon, JA Fallowfield |
Alcoholism, clinical and experimental research | 2011 |
|
Pathogenesis of alcohol-induced liver disease: Classical concepts and recent advances
D Seth, PS Haber, WK Syn, AM Diehl, CP Day |
Journal of Gastroenterology and Hepatology | 2011 |
|
Matrix Metalloproteinase-13 Promotes Recovery from Experimental Liver Cirrhosis in Rats
H Endo, M Niioka, Y Sugioka, J Itoh, K Kameyama, I Okazaki, R Ala-Aho, VM Kähäri, T Watanabe |
Pathobiology | 2011 |
|
Dendritic Cells in Alcoholic Liver Injury and Fibrosis
C Aloman, SL Friedman, M Merad |
Alcoholism, clinical and experimental research | 2011 |
|
Tocotrienols have potent antifibrogenic effects in human intestinal fibroblasts
J Luna, MC Masamunt, M Rickmann, R Mora, C España, S Delgado, J Llach, E Vaquero, M Sans |
Inflammatory Bowel Diseases | 2011 |
|
Effects of Chinese herbal medicine Yiguanjian Decoction on collagen metabolism of hepatic tissues in rats with CCl4-induced liver fibrosis
XN Wang |
Journal of Chinese Integrative Medicine | 2011 |
|
Using ultrasound Nakagami imaging to assess liver fibrosis in rats
MC Ho, JJ Lin, YC Shu, CN Chen, KJ Chang, CC Chang, PH Tsui |
Ultrasonics | 2011 |
|
Inhibition of PDGF, TGF-β, and Abl signaling and reduction of liver fibrosis by the small molecule Bcr-Abl tyrosine kinase antagonist Nilotinib
Y Liu, Z Wang, SQ Kwong, EL Lui, SL Friedman, FR Li, RW Lam, GC Zhang, H Zhang, T Ye |
Journal of Hepatology | 2011 |
|
Neferine inhibits cultured hepatic stellate cell activation and facilitates apoptosis: A possible molecular mechanism
H Ding, J Shi, Y Wang, J Guo, J Zhao, L Dong |
European Journal of Pharmacology | 2011 |
|
Ursolic acid ameliorates hepatic fibrosis in the rat by specific induction of apoptosis in hepatic stellate cells
X Wang, K Ikejima, K Kon, K Arai, T Aoyama, K Okumura, W Abe, N Sato, S Watanabe |
Journal of Hepatology | 2011 |
|
Dimethylnitrosamine-Induced Liver Fibrosis and Recovery in NOD/SCID Mice
MK HYON, E KWON, HJ CHOI, BC KANG |
Journal of Veterinary Medical Science | 2011 |
|
Hepatic Regeneration after Sublethal Partial Liver Irradiation in Cirrhotic Rats
K GU, ST LAI, NY MA, JD ZHAO, ZG REN, J WANG, J LIU, GL JIANG |
Journal of Radiation Research | 2011 |
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<![CDATA[Icaritin delays CCl<SUB>4</SUB>-induced hepatic cirrhosis in rats by protecting hepatocytes from oxidative injury]]> : Icaritin delays CCl<SUB>4</SUB>-induced hepatic cirrhosis in rats by protecting hepatocytes from oxidative injury
H QIAN, P LIU, J LI, L CHEN, L CAO, R ZHANG, Z YIN |
Academic Journal of Second Military Medical University | 2011 |
|
Cannabidiol causes activated hepatic stellate cell death through a mechanism of endoplasmic reticulum stress-induced apoptosis
MP Lim, LA Devi, R Rozenfeld |
Cell Death and Disease | 2011 |
|
Human matrix metalloproteinases: An ubiquitarian class of enzymes involved in several pathological processes
D Sbardella, GF Fasciglione, M Gioia, C Ciaccio, GR Tundo, S Marini, M Coletta |
Molecular Aspects of Medicine | 2011 |
|
NP603, a novel and potent inhibitor of FGFR1 tyrosine kinase, inhibits hepatic stellate cell proliferation and ameliorates hepatic fibrosis in rats
N Lin, S Chen, W Pan, L Xu, K Hu, R Xu |
American journal of physiology. Cell physiology | 2011 |
|
Mesenchymal cell proliferation and programmed cell death: key players in fibrogenesis and new targets for therapeutic intervention
J Luna, MC Masamunt, IC Lawrance, M Sans |
AJP Gastrointestinal and Liver Physiology | 2011 |
|
Assessment of the protective effects of oral tocotrienols in arginine chronic-like pancreatitis
AM González, T Garcia, E Samper, M Rickmann, EC Vaquero, X Molero |
AJP Gastrointestinal and Liver Physiology | 2011 |
|
Pathogenesis and treatment of hepatic fibrosis: is cirrhosis reversible?
Jonathan Fallowfield, Peter Hayes |
Clinical Medicine | 2011 |
|
RETRACTION: Indole-3-Carbinol Enhances the Resolution of Rat Liver Fibrosis and Stimulates Hepatic Stellate Cell Apoptosis by Blocking the Inhibitor of κB Kinase α/Inhibitor of κB-α/Nuclear Factor-κB Pathway
J Ping, A Gao, H Qin, X Wei, J Bai, L Liu, X Li, R Li, Y Ao, H Wang |
The Journal of pharmacology and experimental therapeutics | 2011 |
|
Macrophage-mediated phagocytosis of apoptotic cholangiocytes contributes to reversal of experimental biliary fibrosis
Y Popov, DY Sverdlov, KR Bhaskar, AK Sharma, G Millonig, E Patsenker, S Krahenbuhl, L Krahenbuhl, D Schuppan |
American journal of physiology. Gastrointestinal and liver physiology | 2010 |
|
Macrophages: master regulators of inflammation and fibrosis
TA Wynn, L Barron |
Seminars in liver disease | 2010 |
|
Thiol redox systems and protein kinases in hepatic stellate cell regulatory processes
AM Brunati, MA Pagano, A Bindoli, MP Rigobello |
Free Radical Research | 2010 |
|
Cell Death and Fibrogenesis
W Mehal, A Imaeda |
Seminars in liver disease | 2010 |
|
Advances in Alcoholic Liver Disease
JI Beier, GE Arteel, CJ McClain |
Current Gastroenterology Reports | 2010 |
|
Circulating fibronectin isoforms predict the degree of fibrosis in chronic hepatitis C
NJ Hackl, C Bersch, P Feick, C Antoni, A Franke, MV Singer, IA Nakchbandi |
Scandinavian Journal of Gastroenterology | 2010 |
|
Physiology and pathophysiology of matrix metalloproteases
T Klein, R Bischoff |
Amino Acids | 2010 |
|
Loss of matrix metalloproteinase-2 amplifies murine toxin-induced liver fibrosis by upregulating collagen I expression
BD Radbill, R Gupta, MC Ramirez, A DiFeo, JA Martignetti, CE Alvarez, SL Friedman, G Narla, R Vrabie, R Bowles, Y Saiman, MB Bansal |
Digestive Diseases and Sciences | 2010 |
|
Noxa mediates hepatic stellate cell apoptosis by proteasome inhibition
IM Seda, JL Mott, Y Akazawa, FJ Barreyro, SF Bronk, SH Kaufmann, GJ Gores |
Hepatology research : the official journal of the Japan Society of Hepatology | 2010 |
|
Hepatic stellate cell (vitamin A-storing cell) and its relative – past, present and future
H Senoo, K Yoshikawa, M Morii, M Miura, K Imai, Y Mezaki |
Cell Biology International | 2010 |
|
A natural process of cirrhosis resolution and deceleration of liver regeneration after thioacetamide withdrawal in a rat model
K Gu, JD Zhao, ZG Ren, NY Ma, ST Lai, J Wang, J Liu, GL Jiang |
Molecular Biology Reports | 2010 |
|
Impact of pan-caspase inhibition in animal models of established steatosis and non-alcoholic steatohepatitis
QM Anstee, D Concas, H Kudo, A Levene, J Pollard, P Charlton, HC Thomas, MR Thursz, RD Goldin |
Journal of Hepatology | 2010 |
|
Long-term entecavir therapy results in the reversal of fibrosis/cirrhosis and continued histological improvement in patients with chronic hepatitis B
TT Chang, YF Liaw, SS Wu, E Schiff, KH Han, CL Lai, R Safadi, SS Lee, W Halota, Z Goodman, YC Chi, H Zhang, R Hindes, U Iloeje, S Beebe, B Kreter |
Hepatology | 2010 |
|
Critical role of the liver in the induction of systemic inflammation in rats with preascitic cirrhosis
M Úbeda, L Muñoz, MJ Borrero, D Díaz, R Francés, J Monserrat, M Lario, L Lledó, J Such, M Álvarez-Mon, A Albillos |
Hepatology | 2010 |
|
New insights into the antifibrotic effects of sorafenib on hepatic stellate cells and liver fibrosis
Y Wang, J Gao, D Zhang, J Zhang, J Ma, H Jiang |
Journal of Hepatology | 2010 |
|
The Combination of Selenium and Vitamin E Inhibits Type I Collagen Formation in Cultured Hepatic Stellate Cells
E Mezey, X Liu, JJ Potter |
Biological Trace Element Research | 2010 |
|
Antifibrotic effects of chronic baicalein administration in a CCl4 liver fibrosis model in rats
H Sun, QM Che, X Zhao, XP Pu |
European Journal of Pharmacology | 2010 |
|
Response of Dental Pulp Cells to Er:YAG Irradiation
A Promklay, P Fuangtharnthip, R Surarit, P Atsawasuwan |
Photomedicine and Laser Surgery | 2010 |
|
Involvement of MMP-9 in peribiliary fibrosis and cholangiocarcinogenesis via Rac1-dependent DNA damage in a hamster model
S Prakobwong, P Yongvanit, Y Hiraku, C Pairojkul, P Sithithaworn, P Pinlaor, S Pinlaor |
International Journal of Cancer | 2010 |
|
Loss of clock gene mPer2 promotes liver fibrosis induced by carbon tetrachloride
P Chen, Z Han, P Yang, L Zhu, Z Hua, J Zhang |
Hepatology Research | 2010 |
|
Garlic extract prevents CCl4-induced liver fibrosis in rats: The role of tissue transglutaminase
G D’Argenio, DC Amoruso, G Mazzone, P Vitaglione, A Romano, MT Ribecco, MR D’Armiento, E Mezza, F Morisco, V Fogliano, N Caporaso |
Digestive and Liver Disease | 2010 |
|
Epithelial to Mesenchymal Transition in Injury of Solid Organs: Fact or Artifact?
JS Duffield |
Gastroenterology | 2010 |
|
Slight activation of nuclear factor kappa-B is associated with increased hepatic stellate cell apoptosis in human schistosomal fibrosis
MM Braz, FS Ramalho, RL Cardoso, S Zucoloto, RS Costa, LN Ramalho |
Acta Tropica | 2010 |
|
The significance of CD14+ monocytes in peripheral blood stem cells for the treatment of rat liver cirrhosis
J Wang, X Zhou, L Cui, L Yan, J Liang, X Cheng, L Qiao, Y Shi, Z Han, Y Cao, Y Han, D Fan |
Cytotherapy | 2010 |
|
La fibrose au cours de l’hépatite B : un processus dynamique
P Bedossa |
Gastroentérologie Clinique et Biologique | 2010 |
|
Preventive effects of a fractioned polysaccharide from a traditional Chinese herbal medical formula (Yu Ping Feng San) on carbon tetrachloride-induced hepatic fibrosis: Effect of YPF-P on CCl 4 -induced hepatic fibrosis
J Wang, J Li, L Shi, X Lv, W Cheng, Y Chen |
Journal of Pharmacy and Pharmacology | 2010 |
|
Comprehensive Toxicology
JM Sands, JW Verlander |
Comprehensive Toxicology | 2010 |
|
Macrophage-mediated phagocytosis of apoptotic cholangiocytes contributes to reversal of experimental biliary fibrosis
Y Popov, DY Sverdlov, KR Bhaskar, AK Sharma, G Millonig, E Patsenker, S Krahenbuhl, L Krahenbuhl, D Schuppan |
AJP Gastrointestinal and Liver Physiology | 2010 |
|
Synergistic antifibrotic efficacy of statin and protein kinase C inhibitor in hepatic fibrosis
JI Yang, JH Yoon, YJ Bang, SH Lee, SM Lee, HJ Byun, SJ Myung, W Kim, HS Lee |
AJP Gastrointestinal and Liver Physiology | 2010 |
|
Molecular Pathology of Liver Diseases
SP Monga |
2010 | |
|
Clinical Hepatology
H Dancygier |
2010 | |
|
Increased susceptibility to exacerbated liver injury in hypercholesterolemic ApoE-deficient mice: potential involvement of oxysterols
N Ferré, M Martínez-Clemente, M López-Parra, A González-Périz, R Horrillo, A Planagumà, J Camps, J Joven, A Tres, F Guardiola, R Bataller, V Arroyo, J Clària |
AJP Gastrointestinal and Liver Physiology | 2009 |
|
Pulmonary surfactant: an immunological perspective
ZC Chroneos, Z Sever-Chroneos, VL Shepherd |
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology | 2009 |
|
Deficiency of nicotinamide adenine dinucleotide phosphate, reduced form oxidase enhances hepatocellular injury but attenuates fibrosis after chronic carbon tetrachloride administration
G Aram, JJ Potter, X Liu, L Wang, MS Torbenson, E Mezey |
Hepatology | 2009 |
|
Apoptotic body engulfment by hepatic stellate cells promotes their survival by the JAK/STAT and Akt/NF-kappaB-dependent pathways
JX Jiang, K Mikami, S Venugopal, Y Li, NJ Török |
Journal of Hepatology | 2009 |
|
Gut Homing Receptors on CD8 T Cells Are Retinoic Acid Dependent and Not Maintained by Liver Dendritic or Stellate Cells
B Eksteen, JR Mora, EL Haughton, NC Henderson, L Lee-Turner, EJ Villablanca, SM Curbishley, AI Aspinall, UH von Andrian, DH Adams |
Gastroenterology | 2009 |
|
Extracts of Lindera obtusiloba induce antifibrotic effects in hepatic stellate cells via suppression of a TGF-β-mediated profibrotic gene expression pattern
M Ruehl, U Erben, K Kim, C Freise, T Dagdelen, S Eisele, W Trowitzsch-Kienast, M Zeitz, J Jia, F Stickel, R Somasundaram |
The Journal of Nutritional Biochemistry | 2009 |
|
Evaluation of intracellular signalling pathways in response to insulin-like growth factor I in apoptotic-resistant activated human hepatic stellate cells
A Gentilini, B Lottini, M Brogi, A Caligiuri, L Cosmi, F Marra, M Pinzani |
Fibrogenesis & Tissue Repair | 2009 |
|
Sensitization of Human Hepatic Stellate Cells to Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand-Induced Apoptosis by Leflunomide
X Tang, J Yang, J Li |
Biological & Pharmaceutical Bulletin | 2009 |
|
Selenium Supplementation Decreases Hepatic Fibrosis in Mice After Chronic Carbon Tetrachloride Administration
M Ding, JJ Potter, X Liu, MS Torbenson, E Mezey |
Biological Trace Element Research | 2009 |
|
Renin-angiotensin system in the pathogenesis of liver fibrosis
RM Pereira, RA Santos, FL da Dias, MM Teixeira, AC Silva |
World journal of gastroenterology : WJG | 2009 |
|
p38-MAPK- and caspase-3-mediated superoxide-induced apoptosis of rat hepatic stellate cells: reversal by retinoic acid
NM Jameel, C Thirunavukkarasu, T Wu, SC Watkins, SL Friedman, CR Gandhi |
Journal of Cellular Physiology | 2009 |
|
Effects of Fructus Piperis Longi extract on fibrotic liver of gamma-irradiated rats
SZ Mansour, H El-Kabany |
Chinese medicine | 2009 |
|
Accelerative effect of leflunomide on recovery from hepatic fibrosis involves TRAIL-mediated hepatic stellate cell apoptosis
X Tang, J Yang, J Li |
Life Sciences | 2009 |
|
Antifibrotic effects of ZK14, a novel nitric oxide-donating biphenyldicarboxylate derivative, on rat HSC-T6 cells and CCl4-induced hepatic fibrosis
L Dai, H Ji, X Kong, Y Zhang |
Acta Pharmacologica Sinica | 2009 |
|
p75 neurotrophin receptor signaling regulates hepatic myofibroblast proliferation and apoptosis in recovery from rodent liver fibrosis
TJ Kendall, S Hennedige, RL Aucott, SN Hartland, MA Vernon, RC Benyon, JP Iredale |
Hepatology | 2009 |
|
Senescence of activated stellate cells: Not just early retirement
J Schrader, J Fallowfield, JP Iredale, K Kowdley, G McCaughan, C Trautwein |
Hepatology | 2009 |
|
Platelets contribute to the reduction of liver fibrosis in mice
M Watanabe, S Murata, I Hashimoto, Y Nakano, O Ikeda, Y Aoyagi, R Matsuo, K Fukunaga, H Yasue, N Ohkohchi |
Journal of Gastroenterology and Hepatology | 2009 |
|
Angiotensin II Activates IκB Kinase Phosphorylation of RelA at Ser536 to Promote Myofibroblast Survival and Liver Fibrosis
F Oakley, V Teoh, G Ching–A–Sue, R Bataller, J Colmenero, JR Jonsson, AG Eliopoulos, MR Watson, D Manas, DA Mann |
Gastroenterology | 2009 |
|
Liver Myofibroblasts Regulate Infiltration and Positioning of Lymphocytes in Human Liver
AP Holt, EL Haughton, PF Lalor, A Filer, CD Buckley, DH Adams |
Gastroenterology | 2009 |
|
Over-expression of C/EBP-α induces apoptosis in cultured rat hepatic stellate cells depending on p53 and peroxisome proliferator-activated receptor-γ
X Wang, G Huang, S Mei, J Qian, J Ji, J Zhang |
Biochemical and Biophysical Research Communications | 2009 |
|
Liver Fibrosis: Challenges of the New Era
RG Wells |
Gastroenterology | 2009 |
|
Improved hepatocyte function of future liver remnant of cirrhotic rats after portal vein ligation: A bonus other than volume shifting
KJ Lin, CH Liao, IT Hsiao, TC Yen, TC Chen, YY Jan, MF Chen, TS Yeh |
Surgery | 2009 |
|
Effects of Salviae miltiorrhizae and salvianolic acid B on microcirculation of liver in mice with portal hypertension
T Tian |
Journal of Chinese Integrative Medicine | 2009 |
|
Unraveling the Spider Web of Hepatic Stellate Cell Apoptosis
M Pinzani |
Gastroenterology | 2009 |
|
Effect of Garlic and Aged Black Garlic on Hyperglycemia and Dyslipidemia in Animal Model of Type 2 Diabetes Mellitus
YJ Seo, OC Gweon, JE Im, YM Lee, MJ Kang, JI Kim |
Journal of Food Science and Nutrition | 2009 |
|
Effect of N-Acetylcysteine on the Matrix Metalloproteinases and Their Inhibitors in Carbon Tetrachloride-Induced Hepatotoxicity
K N, KS Al-Numair, AH Al-Assaf, AA Al-Shatwi, M Vp |
Journal of Food Science and Nutrition | 2009 |
|
Inverse association between hepatic stellate cell apoptosis and fibrosis in chronic hepatitis C virus infection
SA Gonzalez, MI Fiel, J Sauk, PW Canchis, RC Liu, L Chiriboga, HT Yee, IM Jacobson, AH Talal |
Journal of Viral Hepatitis | 2009 |
|
Therapeutic Effect of Puerarin on Non-Alcoholic Rat Fatty Liver by Improving Leptin Signal Transduction through JAK2/STAT3 Pathways
P Zheng, G Ji, Z Ma, T Liu, L Xin, H Wu, X Liang, J Liu |
The American journal of Chinese medicine | 2009 |
|
Pancreatitis-Associated Protein Inhibits Human Pancreatic Stellate Cell MMP-1 and -2, TIMP-1 and -2 Secretion and RECK Expression
L Li, MG Bachem, S Zhou, Z Sun, J Chen, M Siech, D Bimmler, R Graf |
Pancreatology | 2009 |
|
Macroscopic models for fibroproliferative disorders: A review
L Fusi |
Mathematical and Computer Modelling | 2009 |
|
Active matrix metalloproteinase-2 promotes apoptosis of hepatic stellate cells via the cleavage of cellular N-cadherin
SN Hartland, F Murphy, RL Aucott, A Abergel, X Zhou, J Waung, N Patel, C Bradshaw, J Collins, D Mann, RC Benyon, JP Iredale |
Liver International | 2009 |
|
Renin-angiotensin system in the pathogenesis of liver fibrosis
RM Pereira, RA Santos, FL da Dias, MM Teixeira, AC Silva |
World journal of gastroenterology : WJG | 2009 |
|
Effect of human umbilical cord blood-derived mesenchymal stem cells in a cirrhotic rat model
KH Jung, HP Shin, S Lee, YJ Lim, SH Hwang, H Han, HK Park, JH Chung, SV Yim |
Liver International | 2009 |
|
Liver under Constant Attack — From Fat to Viruses
CP Day, AW Lohse, PR Galle, SS Thorgeirsson |
2009 | |
|
Reversibility of liver fibrosis
P Ramachandran, JP Iredale |
ANN HEPATOL | 2009 |
|
Antibody-targeted myofibroblast apoptosis reduces fibrosis during sustained liver injury
A Douglass, K Wallace, R Parr, J Park, E Durward, I Broadbent, C Barelle, AJ Porter, MC Wright |
Journal of Hepatology | 2008 |
|
Cellular and molecular mechanisms of liver injury
H Malhi, GJ Gores |
Gastroenterology | 2008 |
|
Cellular and molecular mechanisms of fibrosis
TA Wynn |
The Journal of Pathology | 2008 |
|
Molecular mechanism of hepatic stellate cell activation and antifibrotic therapeutic strategies
JT Li, ZX Liao, J Ping, D Xu, H Wang |
Journal of Gastroenterology | 2008 |
|
NF-κB signaling, liver disease and hepatoprotective agents
B Sun, M Karin |
Oncogene | 2008 |
|
Targeting liver myofibroblasts: a novel approach in anti-fibrogenic therapy
A Douglass, K Wallace, M Koruth, C Barelle, AJ Porter, MC Wright |
Hepatology International | 2008 |
|
Immune Interactions in Hepatic Fibrosis
AP Holt, M Salmon, CD Buckley, DH Adams |
Clinics in Liver Disease | 2008 |
|
Attenuation of experimental autoimmune hepatitis by exogenous and endogenous cannabinoids: involvement of regulatory T cells
VL Hegde, S Hegde, BF Cravatt, LJ Hofseth, M Nagarkatti, PS Nagarkatti |
Molecular pharmacology | 2008 |
|
Hepatic fibrosis—Overview
SL Friedman |
Toxicology | 2008 |
|
Fibrosis and Cirrhosis Reversibility: Clinical Features and Implications
M Pinzani, F Vizzutti |
Clinics in Liver Disease | 2008 |
|
Advances in antifibrotic therapy
Z Ghiassi-Nejad, SL Friedman |
Expert Review of Gastroenterology & Hepatology | 2008 |
|
Induction of matrix metalloproteinase-1 gene transcription by tumour necrosis factor α via the p50/p50 homodimer of nuclear factor-κ B in activated human hepatic stellate cells
S Hozawa, T Nakamura, M Nakano, M Adachi, H Tanaka, Y Takahashi, M Tetsuya, N Miyata, H Soma, T Hibi |
Liver International | 2008 |
|
PTK787/ZK22258 attenuates stellate cell activation and hepatic fibrosis in vivo by inhibiting VEGF signaling
Y Liu, EL Lui, SL Friedman, L Li, T Ye, Y Chen, RT Poon, J Wo, TW Kok, ST Fan |
Laboratory Investigation | 2008 |
|
Insulin-like growth factor-I receptor blockade improves outcome in mouse model of lung injury
JE Choi, SS Lee, DA Sunde, I Huizar, KL Haugk, VJ Thannickal, R Vittal, SR Plymate, LM Schnapp |
American journal of respiratory and critical care medicine | 2008 |
|
Effects of TGF-beta1 Ribbon Antisense on CCl(4)-induced Liver Fibrosis
D Kyung-Oh |
The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology | 2008 |
|
Notch1 signaling stimulates proliferation of immature cardiomyocytes
C Collesi, L Zentilin, G Sinagra, M Giacca |
The Journal of Cell Biology | 2008 |
|
Fucoidan partly prevents CCl4-induced liver fibrosis
S Hayashi, A Itoh, K Isoda, M Kondoh, M Kawase, K Yagi |
European Journal of Pharmacology | 2008 |
|
Emerging drugs for complications of end-stage liver disease
JK Dowman, AP Holt, PN Newsome, DH Adams |
Expert Opinion on Emerging Drugs | 2008 |
|
Proteomics in liver fibrosis is more than meets the eye
KJ Cheung, K Tilleman, D Deforce, I Colle, HV Vlierberghe |
European Journal of Gastroenterology & Hepatology | 2008 |
|
Inhibition of hepatic stellate cell activation following Yinchenhao decoction administration to dimethylnitrosamine-treated rats
C Liu, M Sun, X Yan, L Han, Y Zhang, C Liu, H El-Nezami, P Liu |
Hepatology Research | 2008 |
|
Halofuginone upregulates the expression of heparanase in thioacetamide-induced liver fibrosis in rats
O Ohayon, N Mawasi, A Pevzner, A Tryvitz, T Gildor, M Pines, M Rojkind, M Paizi, G Spira |
Laboratory Investigation | 2008 |
|
Bone Marrow Multipotent Mesenchymal Stromal Cells Do Not Reduce Fibrosis or Improve Function in a Rat Model of Severe Chronic Liver Injury
AB Carvalho, LF Quintanilha, JV Dias, BD Paredes, EG Mannheimer, FG Carvalho, KD Asensi, B Gutfilen, LM Fonseca, CM Resende, GF Rezende, CM Takiya, AC de Carvalho, RC Goldenberg |
Stem Cells | 2008 |
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Polaprezinc attenuates liver fibrosis in a mouse model of non-alcoholic steatohepatitis
H Sugino, N Kumagai, S Watanabe, K Toda, O Takeuchi, S Tsunematsu, S Morinaga, K Tsuchimoto |
Journal of Gastroenterology and Hepatology | 2008 |
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Ceramide inhibition of MMP-2 expression and human cancer bronchial cell invasiveness involve decreased histone acetylation
R Debret, S Brassart-Pasco, J Lorin, A Martoriati, A Deshorgue, FX Maquart, W Hornebeck, I Rahman, F Antonicelli |
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research | 2008 |
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Inhibition of inducible nitric oxide synthase activity prevents liver recovery in rat thioacetamide-induced fibrosis reversal
O Lukivskaya, E Patsenker, R Lis, VU Buko |
European Journal of Clinical Investigation | 2008 |
|
Effects of silymarin on the resolution of liver fibrosis induced by carbon tetrachloride in rats
JH Tsai, JY Liu, TT Wu, PC Ho, CY Huang, JC Shyu, YS Hsieh, CC Tsai, YC Liu |
Journal of Viral Hepatitis | 2008 |
|
Value of Fibrosis Markers for Staging Liver Fibrosis in Patients With Precirrhotic Alcoholic Liver Disease
CS Lieber, DG Weiss, F Paronetto |
Alcoholism, clinical and experimental research | 2008 |
|
Lack of inducible nitric oxide synthase leads to increased hepatic apoptosis and decreased fibrosis in mice after chronic carbon tetrachloride administration
G Aram, JJ Potter, X Liu, MS Torbenson, E Mezey |
Hepatology | 2008 |
|
Gc-globulin (vitamin D binding protein) is synthesized and secreted by hepatocytes and internalized by hepatic stellate cells through Ca2+-dependent interaction with the megalin/gp330 receptor
OA Gressner, B Lahme, AM Gressner |
Clinica Chimica Acta | 2008 |
|
RNA interfering connective tissue growth factor prevents rat hepatic stellate cell activation and extracellular matrix production
G Li, D Li, Q Xie, Y Shi, S Jiang, Y Jin |
The Journal of Gene Medicine | 2008 |
|
Functional hepatic recovery after xenotransplantation of cryopreserved fetal liver cells or soluble cell-factor administration in a cirrhotic rat model: Are viable cells necessary?
OV Ochenashko, YV Nikitchenko, NA Volkova, SP Mazur, AY Somov, BJ Fuller, AY Petrenko |
Journal of Gastroenterology and Hepatology | 2008 |
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Hepatocyte growth factor gene transfer with naked plasmid DNA ameliorates dimethylnitrosamine-induced liver fibrosis in rats
H Kanemura, Y Iimuro, M Takeuchi, T Ueki, T Hirano, K Horiguchi, Y Asano, J Fujimoto |
Hepatology Research | 2008 |
|
Systematic review: hepatic fibrosis - regression with therapy
CD Zois, GH Baltayiannis, P Karayiannis, EV Tsianos |
Alimentary Pharmacology & Therapeutics | 2008 |
|
Fibrosis and Cirrhosis Reversibility – Molecular Mechanisms
RG Gieling, AD Burt, DA Mann |
Clinics in Liver Disease | 2008 |
|
Cholestasis: Current Issues and Plan for the Future
B Haber, CT Ferreira, M Aw, J Bezerra, E Sturm, R Thompson, D DʼAgostino, P McKiernan |
Journal of Pediatric Gastroenterology and Nutrition | 2008 |
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NF-κB is a critical regulator of the survival of rodent and human hepatic myofibroblasts
MR Watson, K Wallace, RG Gieling, DM Manas, E Jaffray, RT Hay, DA Mann, F Oakley |
Journal of Hepatology | 2008 |
|
An ultrasound and histomorphological analysis of experimental liver cirrhosis in rats
JV Dias, BD Paredes, LF Mesquita, AB Carvalho, EO Kozlowski, AS Lessa, CM Takiya, CM Resende, HS Coelho, AC Campos-de-Carvalho, GF Rezende, RC Goldenberg |
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas / Sociedade Brasileira de Biofisica ... [et al.] | 2008 |
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Endocannabinoids and Liver Disease. II. Endocannabinoids in the pathogenesis and treatment of liver fibrosis
SV Siegmund, RF Schwabe |
AJP Gastrointestinal and Liver Physiology | 2008 |
|
PDGF-Receptor β-Targeted Adenovirus Redirects Gene Transfer from Hepatocytes to Activated Stellate Cells
MH Schoemaker, MG Rots, L Beljaars, AY Ypma, PL Jansen, K Poelstra, H Moshage, HJ Haisma |
Molecular Pharmaceutics | 2008 |
|
Novel Role of IL-13 in Fibrosis Induced by Nonalcoholic Steatohepatitis and Its Amelioration by IL-13R-Directed Cytotoxin in a Rat Model
T Shimamura, T Fujisawa, SR Husain, M Kioi, A Nakajima, RK Puri |
Journal of immunology (Baltimore, Md. : 1950) | 2008 |
|
Matrix Metalloproteinases in Tissue Remodelling and Inflammation
V Lagente, E Boichot |
2008 | |
|
The Desmoplastic Reaction Surrounding Hepatic Colorectal Adenocarcinoma Metastases Aids Tumor Growth and Survival via α v Integrin Ligation
JA Conti, TJ Kendall, A Bateman, TA Armstrong, A Papa-Adams, Q Xu, G Packham, JN Primrose, RC Benyon, JP Iredale |
Clinical cancer research | 2008 |
|
Models of Liver Fibrosis: Exploring the dynamic nature of inflammation and repair in a solid organ
J. P. Iredale |
Journal of Clinical Investigation | 2007 |
|
Significance and Therapeutic Potential of Endothelial Progenitor Cell Transplantation in a Cirrhotic Liver Rat Model
T Nakamura, T Torimura, M Sakamoto, O Hashimoto, E Taniguchi, K Inoue, R Sakata, R Kumashiro, T Murohara, T Ueno, M Sata |
Gastroenterology | 2007 |
|
Bioconjugation of Oligonucleotides for Treating Liver Fibrosis
Z Ye, HS Houssein, RI Mahato |
Oligonucleotides | 2007 |
|
Targeting 15d-prostaglandin J2 to hepatic stellate cells: two options evaluated
WI Hagens, A Mattos, R Greupink, A Jager-Krikken, C Reker-Smit, A Loenen-Weemaes, IA Gouw, K Poelstra, L Beljaars |
Pharmaceutical Research | 2007 |
|
Disruption of tissue-type plasminogen activator gene in mice aggravated liver fibrosis
Y Hsiao, T Zou, CC Ling, H Hu, XM Tao, HY Song |
Journal of Gastroenterology and Hepatology | 2007 |
|
Bone marrow-derived cells express matrix metalloproteinases and contribute to regression of liver fibrosis in mice
R Higashiyama, Y Inagaki, YY Hong, M Kushida, S Nakao, M Niioka, T Watanabe, H Okano, Y Matsuzaki, G Shiota, I Okazaki |
Hepatology | 2007 |
|
The endocannabinoid 2-arachidonoyl glycerol induces death of hepatic stellate cells via mitochondrial reactive oxygen species
SV Siegmund, T Qian, S de Minicis, J Harvey-White, G Kunos, KY Vinod, B Hungund, RF Schwabe |
The FASEB Journal | 2007 |
|
Apoptosis in the initiation, modulation and termination of the corneal wound healing response
SE Wilson, SS Chaurasia, FW Medeiros |
Experimental Eye Research | 2007 |
|
Matrix Metalloproteinase Gene Delivery for Liver Fibrosis
Y Iimuro, DA Brenner |
Pharmaceutical Research | 2007 |
|
Comparative Protection against Liver Inflammation and Fibrosis by a Selective Cyclooxygenase-2 Inhibitor and a Nonredox-Type 5-Lipoxygenase Inhibitor
R Horrillo, A Planagumà, A González-Périz, N Ferré, E Titos, R Miquel, M López-Parra, JL Masferrer, V Arroyo, J Clària |
The Journal of pharmacology and experimental therapeutics | 2007 |
|
Mononuclear cells modulate the activity of pancreatic stellate cells which in turn promote fibrosis and inflammation in chronic pancreatitis
CW Michalski, A Gorbachevski, M Erkan, C Reiser, S Deucker, F Bergmann, T Giese, M Weigand, NA Giese, H Friess, J Kleeff |
Journal of Translational Medicine | 2007 |
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Interferon-β reduces the mouse liver fibrosis induced by repeated administration of concanavalin A via the direct and indirect effects
J Tanabe, A Izawa, N Takemi, Y Miyauchi, Y Torii, H Tsuchiyama, T Suzuki, S Sone, K Ando |
Immunology | 2007 |
|
Epimorphin, a morphogenic protein, induces proteases in rodent hepatocytes through NF-κB
K Miura, R Yoshino, Y Hirai, T Goto, S Ohshima, K Mikami, K Yoneyama, D Watanabe, M Sato, H Senoo, Y Kodama, Y Osawa, DA Brenner, S Watanabe |
Journal of Hepatology | 2007 |
|
Sinusoidal remodeling and angiogenesis: A new function for the liver-specific pericyte?
JS Lee, D Semela, J Iredale, VH Shah |
Hepatology | 2007 |
|
Both Plasma Lysophosphatidic Acid and Serum Autotaxin Levels are Increased in Chronic Hepatitis C
N Watanabe, H Ikeda, K Nakamura, R Ohkawa, Y Kume, J Aoki, K Hama, S Okudaira, M Tanaka, T Tomiya, M Yanase, K Tejima, T Nishikawa, M Arai, H Arai, M Omata, K Fujiwara, Y Yatomi |
Journal of Clinical Gastroenterology | 2007 |
|
The Role of Activated Hepatic Stellate Cells in Liver Fibrosis, Portal Hypertension and Cancer Angiogenesis
JS Lee, JH Kim |
The Korean Journal of Hepatology | 2007 |
|
Spirulina in Human Nutrition and Health
L Wu, JA Ho |
Spirulina in Human Nutrition and Health | 2007 |
|
Immunomodulation of activated hepatic stellate cells by mesenchymal stem cells
B Parekkadan, D Poll, Z Megeed, N Kobayashi, AW Tilles, F Berthiaume, ML Yarmush |
Biochemical and Biophysical Research Communications | 2007 |
|
Gene modulation for treating liver fibrosis
K Cheng, RI Mahato |
Critical reviews in therapeutic drug carrier systems | 2007 |
|
Is cirrhosis of the liver reversible?
M Kumar, SK Sarin |
The Indian Journal of Pediatrics | 2007 |
|
Resolving fibrosis in the diseased liver: Translating the scientific promise to the clinic
AK Muddu, IN Guha, AM Elsharkawy, DA Mann |
The International Journal of Biochemistry & Cell Biology | 2007 |
|
Gene Expression Profile Analysis of the Spontaneous Reversal of Rat Hepatic Fibrosis by cDNA Microarray
Q Pan, ZB Zhang, X Zhang, J Shi, YX Chen, ZG Han, WF Xie |
Digestive Diseases and Sciences | 2007 |
|
The Beneficial Effect of Aspirin and Enoxaparin on Fibrosis Progression and Regenerative Activity in a Rat Model of Cirrhosis
N Assy, O Hussein, A Khalil, A Luder, S Szvalb, M Paizi, G Spira |
Digestive Diseases and Sciences | 2007 |
|
Changes in the expression of genes related to apoptosis and fibrosis pathways in CCl4-treated rats
J Marsillach, N Ferré, J Camps, A Rull, R Beltran, J Joven |
Molecular and Cellular Biochemistry | 2007 |
|
Tocotrienols Induce Apoptosis and Autophagy in Rat Pancreatic Stellate Cells Through the Mitochondrial Death Pathway
M Rickmann, EC Vaquero, JR Malagelada, X Molero |
Gastroenterology | 2007 |
|
Hepatocyte growth factor promotes remodeling of murine liver fibrosis, accelerating recruitment of bone marrow-derived cells into the liver
Y Asano, Y Iimuro, G Son, T Hirano, J Fujimoto |
Hepatology Research | 2007 |
|
Possible inhibitory effect of oral zinc supplementation on hepatic fibrosis through downregulation of TIMP-1: A pilot study
M Takahashi, H Saito, M Higashimoto, T Hibi |
Hepatology Research | 2007 |
|
Liver Fibrosis: Possible Involvement of EMT
T Ikegami, Y Zhang, Y Matsuzaki |
Cells Tissues Organs | 2007 |
|
Hepatic viscoelastic parameters measured with MR elastography: Correlations with quantitative analysis of liver fibrosis in the rat
N Salameh, F Peeters, R Sinkus, J Abarca-Quinones, L Annet, LC Beek, I Leclercq, BE van Beers |
Journal of Magnetic Resonance Imaging | 2007 |
|
Modified synthetic siRNA targeting tissue inhibitor of metalloproteinase-2 inhibits hepatic fibrogenesis in rats
YB Hu, DG Li, HM Lu |
The Journal of Gene Medicine | 2007 |
|
Effect of Chinese traditional compound, Gan-fu-kang, on CCl4-induced liver fibrosis in rats and its probable molecular mechanisms
TT Xu, MN Jiang, C Li, Y Che, YJ Jia |
Hepatology Research | 2007 |
|
Efficiency of Cupressus sempiverens L. and Juniperus phoenicea Against Carbon Tetrachloride Hepatotoxicity in Rats
MZ ., MS ., HM ., SA ., NA ., MM . |
Trends in Medical Research | 2007 |
|
A functional Fas promoter polymorphism is associated with a severe phenotype in type 1 autoimmune hepatitis characterized by early development of cirrhosis
K Agarwal, AJ Czaja, PT Donaldson |
Tissue Antigens | 2007 |
|
Hepatocyte growth factor: a regenerative drug for acute hepatitis and liver cirrhosis
S Mizuno, T Nakamura |
Regenerative Medicine | 2007 |
|
Hepatic stellate cell activation in liver transplant patients with hepatitis C recurrence and in non-transplanted patients with chronic hepatitis C
L Cisneros, MC Londoño, C Blasco, R Bataller, R Miquel, M Bruguera, P Ginès, A Rimola |
Liver Transplantation | 2007 |
|
Effect of fetuin, a TGFβ antagonist and pentoxifylline, a cytokine antagonist on hepatic stellate cell function and fibrotic parameters in fibrosis
M Verma-Gandhu, MR Peterson, TC Peterson |
European Journal of Pharmacology | 2007 |
|
Bakuchiol-induced caspase-3-dependent apoptosis occurs through c-Jun NH2-terminal kinase-mediated mitochondrial translocation of Bax in rat liver myofibroblasts
EJ Park, YZ Zhao, YC Kim, DH Sohn |
European Journal of Pharmacology | 2007 |
|
Induced hypothyroidism accelerates the regression of liver fibrosis in rats
R Bruck, S Weiss, A Traister, I Zvibel, H Aeed, Z Halpern, R Oren |
Journal of Gastroenterology and Hepatology | 2007 |
|
Effects and mechanisms of extract from Paeonia lactiflora and Astragalus membranaceus on liver fibrosis induced by carbon tetrachloride in rats
WY Sun, W Wei, L Wu, SY Gui, H Wang |
Journal of Ethnopharmacology | 2007 |
|
Fibrogenic cell fate during fibrotic tissue remodelling observed in rat and human cultured liver slices
C Guyot, C Combe, C Balabaud, P Bioulac-Sage, A Desmoulière |
Journal of Hepatology | 2007 |
|
Expression of MMPs and TIMPs in liver fibrosis – a systematic review with special emphasis on anti-fibrotic strategies
S Hemmann, J Graf, M Roderfeld, E Roeb |
Journal of Hepatology | 2007 |
|
A Useful Model to Audit Liver Resolution from Cirrhosis in Rats Using Functional Proteomics
EH Liu, MF Chen, TS Yeh, YP Ho, RC Wu, TC Chen, YY Jan, TL Pan |
Journal of Surgical Research | 2007 |
|
Comprehensive characterization of serum clinical chemistry parameters and the identification of urinary superoxide dismutase in a carbon tetrachloride-induced model of hepatic fibrosis in the female Hanover Wistar rat
R Smyth, MR Munday, MJ York, CJ Clarke, T Dare, JA Turton |
International Journal of Experimental Pathology | 2007 |
|
CD95 activation in the liver: Ion fluxes and oxidative signaling
R Reinehr, D Häussinger |
Archives of Biochemistry and Biophysics | 2007 |
|
Cellular targeting of the apoptosis-inducing compound gliotoxin to fibrotic rat livers
WI Hagens, L Beljaars, DA Mann, MC Wright, B Julien, S Lotersztajn, C Reker-Smit, K Poelstra |
The Journal of pharmacology and experimental therapeutics | 2007 |
|
Contribution of mononuclear bone marrow cells to carbon tetrachloride-induced liver fibrosis in rats
Bao-Qiang Cao, Ji-Zong Lin, Yue-Si Zhong, Shao-Bin Huang, Nan Lin, Zhao-Feng Tang, Rui Chen, Peng Xiang, Rui-Yun Xu |
2007 | |
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Screening for genes involved in apoptosis of hepatic stellate cells : a role of caspase-7
Y Kawakubo, Y Takei, K Izumi, S Yamashina, K Kon, N Enomoto, S Suzuki, K Ikejima, H Okubo, N Sato |
2007 | |
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Pegylated interferon-alpha plus taurine in treatment of rat liver fibrosis
Ilker Tasci, Mehmet Refik Mas, Sevil Atalay Vural, Salih Deveci, Bilgin Comert, Gunay Alcigir, Nuket Mas, Cemal Akay, Mithat Bozdayi, Cihan Yurdaydin, Hakan Bozkaya, Ozden Uzunalimoglu, Ahmet Turan Isik, Harun M Said |
World journal of gastroenterology : WJG | 2007 |
|
Increased stiffness of the rat liver precedes matrix deposition: implications for fibrosis
PC Georges, JJ Hui, Z Gombos, ME McCormick, AY Wang, M Uemura, R Mick, PA Janmey, EE Furth, RG Wells |
AJP Gastrointestinal and Liver Physiology | 2007 |
|
Selective inactivation of NF-κB in the liver using NF-κB decoy suppresses CCl 4 -induced liver injury and fibrosis
G Son, Y Iimuro, E Seki, T Hirano, Y Kaneda, J Fujimoto |
AJP Gastrointestinal and Liver Physiology | 2007 |
|
Liver Immunology
ME Gershwin, JM Vierling, MP Manns |
2007 | |
|
Local Inhibition of Liver Fibrosis by Specific Delivery of a Platelet-Derived Growth Factor Kinase Inhibitor to Hepatic Stellate Cells
T Gonzalo, L Beljaars, M van de Bovenkamp, K Temming, AM van Loenen, C Reker-Smit, DK Meijer, M Lacombe, F Opdam, G Kéri, L Örfi, K Poelstra, RJ Kok |
The Journal of pharmacology and experimental therapeutics | 2007 |
|
Scar-Associated Macrophages Are a Major Source of Hepatic Matrix Metalloproteinase-13 and Facilitate the Resolution of Murine Hepatic Fibrosis
JA Fallowfield, M Mizuno, TJ Kendall, CM Constandinou, RC Benyon, JS Duffield, JP Iredale |
Journal of immunology (Baltimore, Md. : 1950) | 2007 |
|
Hepatic Stellate Cells and Liver Fibrosis
RK Moreira |
Archives of pathology & laboratory medicine | 2007 |
|
Liver fibrosis induced by hepatic overexpression of PDGF-B in transgenic mice
P Czochra, B Klopcic, E Meyer, J Herkel, JF Garcia-Lazaro, F Thieringer, P Schirmacher, S Biesterfeld, PR Galle, AW Lohse, S Kanzler |
Journal of Hepatology | 2006 |
|
JunD is a profibrogenic transcription factor regulated by Jun N-terminal kinase-independent phosphorylation
DE Smart, K Green, F Oakley, JB Weitzman, M Yaniv, G Reynolds, J Mann, H Millward-Sadler, DA Mann |
Hepatology | 2006 |
|
Inhibition of hepatic fibrogenesis by matrix metalloproteinase-9 mutants in mice
M Roderfeld, R Weiskirchen, S Wagner, ML Berres, C Henkel, J Grötzinger, AM Gressner, S Matern, E Roeb |
The FASEB Journal | 2006 |
|
Cytoglobin overexpression protects against damage-induced fibrosis
R Xu, PM Harrison, M Chen, L Li, T Tsui, PC Fung, P Cheung, G Wang, H Li, Y Diao, GW Krissansen, S Xu, F Farzaneh |
Molecular Therapy | 2006 |
|
Sustained activation of Rac1 in hepatic stellate cells promotes liver injury and fibrosis in mice
SS Choi, JK Sicklick, Q Ma, L Yang, J Huang, Y Qi, W Chen, YX Li, PJ Goldschmidt-Clermont, AM Diehl |
Hepatology | 2006 |
|
Natural killer cells ameliorate liver fibrosis by killing activated stellate cells in NKG2D-dependent and tumor necrosis factor-related apoptosis-inducing ligand-dependent manners
S Radaeva, R Sun, B Jaruga, VT Nguyen, Z Tian, B Gao |
Gastroenterology | 2006 |
|
Galectin-3 regulates myofibroblast activation and hepatic fibrosis
NC Henderson, AC Mackinnon, SL Farnworth, F Poirier, FP Russo, JP Iredale, C Haslett, KJ Simpson, T Sethi |
Proceedings of the National Academy of Sciences | 2006 |
|
Reversal of Fibrosis: No Longer a Pipe Dream?
JA Fallowfield, TJ Kendall, JP Iredale |
Clinics in Liver Disease | 2006 |
|
TIMP-1 Transgenic Mice Recover From Diabetes Induced by Multiple Low-Dose Streptozotocin
H Jiang, H Zhu, X Chen, Y Peng, J Wang, F Liu, S Shi, B Fu, Y Lu, Q Hong, Z Feng, K Hou, X Sun, G Cai, X Zhang, Y Xie |
2006 | |
|
Mining the acute respiratory distress syndrome proteome: identification of the insulin-like growth factor (IGF)/IGF-binding protein-3 pathway in acute lung injury
LM Schnapp, S Donohoe, J Chen, DA Sunde, PM Kelly, J Ruzinski, T Martin, DR Goodlett |
The American Journal of Pathology | 2006 |
|
Rat liver fibrosis regresses better with pegylated interferon alpha2b and ursodeoxycholic acid treatments than spontaneous recovery
II Tasci, MR Mas, SA Vural, B Comert, G Alcigir, M Serdar, N Mas, AT Isik, Y Ates |
Liver International | 2006 |
|
Cytokine blockade inhibits hepatic tissue inhibitor of metalloproteinase-1 expression and up-regulates matrix metalloproteinase-9 in toxic liver injury
M Roderfeld, A Geier, CG Dietrich, E Siewert, B Jansen, C Gartung, E Roeb |
Liver International | 2006 |
|
Antifibrotic Agents for Liver Disease
E Albanis, SL Friedman |
American Journal of Transplantation | 2006 |
|
Antifibrotic targets and therapy in HCV
E Albanis, SL Friedman |
Current Hepatitis Reports | 2006 |
|
Overexpression of Bcl-2 by activated human hepatic stellate cells: resistance to apoptosis as a mechanism of progressive hepatic fibrogenesis in humans
E Novo, F Marra, E Zamara, LV di Bonzo, L Monitillo, S Cannito, I Petrai, A Mazzocca, A Bonacchi, RS de Franco, S Colombatto, R Autelli, M Pinzani, M Parola |
Gut | 2006 |
|
Mechanisms of liver fibrosis
S Tsukada, CJ Parsons, RA Rippe |
Clinica Chimica Acta | 2006 |
|
Effects and mechanisms of crude astragalosides fraction on liver fibrosis in rats
SY Gui, W Wei, H Wang, L Wu, WY Sun, W Chen, CY Wu |
Journal of Ethnopharmacology | 2006 |
|
In Vitro and In Vivo Protection of Stellate Cells from Apoptosis by Leptin
A Qamar, SZ Sheikh, A Masud, MN Jhandier, IB Inayat, W Hakim, WZ Mehal |
Digestive Diseases and Sciences | 2006 |
|
Inhibitory Effect of Emodin on Tissue Inhibitor of Metalloproteinases-1 (TIMP-1) Expression in Rat Hepatic Stellate Cells
M Gui, YF Zhang, ZY Xiao, P Sun, JF Dai, SF Wang, YC Rui, JP Zhang |
Digestive Diseases and Sciences | 2006 |
|
Attenuated liver fibrosis in the absence of B cells
AP Holt, Z Stamataki, DH Adams |
Hepatology | 2006 |
|
Proteasome inhibition induces hepatic stellate cell apoptosis
A Anan, ES Baskin-Bey, SF Bronk, NW Werneburg, VH Shah, GJ Gores |
Hepatology | 2006 |
|
Colchicine inhibited the expression of tissue inhibitor of metalloprotenase-1 and interleukin-6 in cultured activated hepatic stellate cells
L Zesong, C Shaoxi, J Yuan, G RuiJun, Z Wen |
Wuhan University Journal of Natural Sciences | 2006 |
|
Mechanisms of alcohol-induced hepatic fibrosis: A summary of the Ron Thurman Symposium
V Purohit, DA Brenner |
Hepatology | 2006 |
|
Gliotoxin non-selectively induces apoptosis in fibrotic and normal livers
WI Hagens, P Olinga, DK Meijer, GM Groothuis, L Beljaars, K Poelstra |
Liver International | 2006 |
|
Involvement of integrin-linked kinase in carbon tetrachloride–induced hepatic fibrosis in rats
Y Zhang, T Ikegami, A Honda, T Miyazaki, B Bouscarel, M Rojkind, I Hyodo, Y Matsuzaki |
Hepatology | 2006 |
|
Fibroblast activation protein: a serine protease expressed at the remodeling interface in idiopathic pulmonary fibrosis
PS Acharya, A Zukas, V Chandan, AL Katzenstein, E Puré |
Human Pathology | 2006 |
|
Loss of MMP 13 attenuates murine hepatic injury and fibrosis during cholestasis
H Uchinami, E Seki, DA Brenner, J D'Armiento |
Hepatology | 2006 |
|
Reversal of hepatic fibrosis — Fact or fantasy?
SL Friedman, MB Bansal |
Hepatology | 2006 |
|
Mechanisms of liver fibrosis: New insights into an old problem
RG Wells |
Drug Discovery Today: Disease Mechanisms | 2006 |
|
Immunohistochemical analysis of α-SMA and GFAP expression in liver stellate cells
N Tomanovic, I Boricic, D Brasanac |
Vojnosanitetski pregled | 2006 |
|
Direct and indirect evidence for the reversibility of cirrhosis
J Serpaggi, F Carnot, B Nalpas, D Canioni, J Guéchot, P Lebray, A Vallet-Pichard, H Fontaine, P Bedossa, S Pol |
Human Pathology | 2006 |
|
Effects of bicyclol on dimethylnitrosamine-induced liver fibrosis in mice and its mechanism of action
QW Hu, GT Liu |
Life Sciences | 2006 |
|
Decrease of type IV collagen and TIMP-1 serum levels after splenectomy in patients with schistosomiasis mansoni
RM Wyszomirska, CC Lacet, LR Tenório, NF Nishimura, MA Mesquita, JB Neto, F Oliveira, MC Balwani, JR Almeida, EC Soares |
Acta Tropica | 2006 |
|
Fibrose hépatique
JF Blanc, V Ledinghen, J Rosenbaum |
EMC - Hépatologie | 2006 |
|
New Therapies in Hepatitis C Virus and Chronic Liver Disease: Antifibrotics
DC Rockey |
Clinics in Liver Disease | 2006 |
|
Hepatic Fibrosis, Stellate Cells, and Portal Hypertension
DC Rockey |
Clinics in Liver Disease | 2006 |
|
Effect of Chinese medicine Qinggan Huoxuefang on inducing HSC apoptosis in alcoholic liver fibrosis rats
G Ji, L Wang, SH Zhang, JW Liu, PY Zheng, T Liu |
World journal of gastroenterology : WJG | 2006 |
|
Modern pathogenetic concepts of liver fibrosis suggest stellate cells and TGF-beta as major players and therapeutic targets
A M Gressner, R Weiskirchen |
Journal of Cellular and Molecular Medicine | 2006 |
|
Impaired Proteolysis of Collagen I Inhibits Proliferation of Hepatic Stellate Cells: IMPLICATIONS FOR REGULATION OF LIVER FIBROSIS
X Zhou, A Jamil, A Nash, J Chan, N Trim, JP Iredale, RC Benyon |
The Journal of biological chemistry | 2006 |
|
Animal models of portal hypertension
JG Abraldes |
World journal of gastroenterology : WJG | 2006 |
|
Emerging Therapies for Liver Fibrosis
AJ Fowell, JP Iredale |
Digestive Diseases | 2006 |
|
The Diabetic Kidney
P Cortes, CE Mogensen |
2006 | |
|
Tissue Repair, Contraction and the Myofibroblast
C Chaponnier, A Desmoulière, G Gabbiani |
2006 | |
|
Disease Progression and Disease Prevention in Hepatology and Gastroenterology
PR Galle, WE Schmidt, G Gerken, B Wiedenmann |
2006 | |
|
Growth inhibition and apoptosis in liver myofibroblasts promoted by hepatocyte growth factor leads to resolution from liver cirrhosis
WH Kim, K Matsumoto, K Bessho, T Nakamura |
The American Journal of Pathology | 2005 |
|
The selective cyclooxygenase-2 inhibitor SC-236 reduces liver fibrosis by mechanisms involving non-parenchymal cell apoptosis and PPARgamma activation
A Planagumà, J Clària, R Miquel, M López-Parra, E Titos, JL Masferrer, V Arroyo, J Rodés |
The FASEB Journal | 2005 |
|
HGF reduces advancing lung fibrosis in mice: a potential role for MMP-dependent myofibroblast apoptosis
S Mizuno, K Matsumoto, MY Li, T Nakamura |
The FASEB Journal | 2005 |
|
Can renal fibrosis be reversed?
AA Eddy |
Pediatric Nephrology | 2005 |
|
HEPATIC FIBROSIS: Molecular Mechanisms and Drug Targets
S Lotersztajn, B Julien, F Teixeira-Clerc, P Grenard, A Mallat |
Annual Review of Pharmacology and Toxicology | 2005 |
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A farnesoid x receptor-small heterodimer partner regulatory cascade modulates tissue metalloproteinase inhibitor-1 and matrix metalloprotease expression in hepatic stellate cells and promotes resolution of liver fibrosis
S Fiorucci, G Rizzo, E Antonelli, B Renga, A Mencarelli, L Riccardi, S Orlandi, M Pruzanski, A Morelli, R Pellicciari |
The Journal of pharmacology and experimental therapeutics | 2005 |
|
Mac the knife? Macrophages– the double-edged sword of hepatic fibrosis
SL Friedman |
Journal of Clinical Investigation | 2005 |
|
Bone marrow-derived mesenchymal stem cells protect against experimental liver fibrosis in rats.
Zhao DC, Lei JX, Chen R, Yu WH, Zhang XM, Li SN, Xiang P |
World Journal of Gastroenterology | 2005 |
|
Selective depletion of macrophages reveals distinct, opposing roles during liver injury and repair
JS Duffield, SJ Forbes, CM Constandinou, S Clay, M Partolina, S Vuthoori, S Wu, R Lang, JP Iredale |
Journal of Clinical Investigation | 2005 |
|
Fasudil hydrochloride hydrate, a Rho-kinase (ROCK) inhibitor, suppresses collagen production and enhances collagenase activity in hepatic stellate cells
M Fukushima, M Nakamuta, M Kohjima, K Kotoh, M Enjoji, N Kobayashi, H Nawata |
Liver International | 2005 |
|
Antifibrotic therapy in chronic liver disease
DC Rockey |
Clinical Gastroenterology and Hepatology | 2005 |
|
Expression of insulin-like growth factor I by activated hepatic stellate cells reduces fibrogenesis and enhances regeneration after liver injury
S Sanz, JB Pucilowska, S Liu, CM Rodríguez-Ortigosa, PK Lund, DA Brenner, CR Fuller, JG Simmons, A Pardo, ML Martínez-Chantar, JA Fagin, J Prieto |
Gut | 2005 |
|
Translocation of p21(Cip1/WAF1) from the nucleus to the cytoplasm correlates with pancreatic myofibroblast to fibroblast cell conversion
F Manapov, P Muller, J Rychly |
Gut | 2005 |
|
Nuclear factor-kappaB1 (p50) limits the inflammatory and fibrogenic responses to chronic injury
F Oakley, J Mann, S Nailard, DE Smart, N Mungalsingh, C Constandinou, S Ali, SJ Wilson, H Millward-Sadler, JP Iredale, DA Mann |
The American Journal of Pathology | 2005 |
|
Comments on cirrhosis reversal
VJ Desmet |
Digestive and Liver Disease | 2005 |
|
Inhibitory effects of idoxifene on hepatic fibrosis in rats
Y ZHOU, D YIN, H CHEN, J SHI, B SHA, X WANG |
Acta Pharmacologica Sinica | 2005 |
|
Enhanced matrix degradation after withdrawal of TGF-beta1 triggers hepatocytes from apoptosis to proliferation and regeneration
E Arendt, U Ueberham, R Bittner, R Gebhardt, E Ueberham |
Cell Proliferation | 2005 |
|
Anandamide induces necrosis in primary hepatic stellate cells
SV Siegmund, H Uchinami, Y Osawa, DA Brenner, RF Schwabe |
Hepatology | 2005 |
|
The role and regulation of hepatic stellate cell apoptosis in reversal of liver fibrosis
AM Elsharkawy, F Oakley, DA Mann |
Apoptosis | 2005 |
|
Zinc finger protein 267 is up-regulated during the activation process of human hepatic stellate cells and functions as a negative transcriptional regulator of MMP-10
B Schnabl, K Hu, M Mühlbauer, C Hellerbrand, B Stefanovic, DA Brenner, J Schölmerich |
Biochemical and Biophysical Research Communications | 2005 |
|
Molecular Pathogenesis of Alcohol-Induced Hepatic Fibrosis
SV Siegmund, DA Brenner |
Alcoholism: Clinical & Experimental Research | 2005 |
|
Molecular Mechanisms of Alcohol-Induced Hepatic Fibrosis
SV Siegmund, S Dooley, DA Brenner |
Digestive Diseases | 2005 |
|
Integrin α8β1–fibronectin interactions promote cell survival via PI3 kinase pathway
E Farias, M Lu, X Li, LM Schnapp |
Biochemical and Biophysical Research Communications | 2005 |
|
Repair after cholestatic liver injury correlates with neutrophil infiltration and matrix metalloproteinase 8 activity
MW Harty, HM Huddleston, EF Papa, T Puthawala, AP Tracy, GA Ramm, S Gehring, SH Gregory, TF Tracy |
Surgery | 2005 |
|
Inhibition of inhibitor of κB kinases stimulates hepatic stellate cell apoptosis and accelerated recovery from rat liver fibrosis
F Oakley, M Meso, JP Iredale, K Green, CJ Marek, X Zhou, MJ May, H Millward-Sadler, MC Wright, DA Mann |
Gastroenterology | 2005 |
|
Matrix Metalloproteinases 2 and 9 Are Markers of Inflammation but Not of the Degree of Fibrosis in Chronic Hepatitis C
S Reif, R Somech, E Brazovski, R Reich, A Belson, FM Konikoff, A Kessler |
Digestion | 2005 |
|
Reversibility of experimental rabbit liver cirrhosis by portal collagenase administration
B Jin, HJ Alter, ZC Zhang, JW Shih, JM Esteban, T Sun, YS Yang, Q Qiu, XL Liu, L Yao, HD Wang, LF Cheng |
Laboratory Investigation | 2005 |
|
MMP-1: the elder of the family
A Pardo, M Selman |
The International Journal of Biochemistry & Cell Biology | 2005 |
|
G-CSF–primed hematopoietic stem cells or G-CSF per se accelerate recovery and improve survival after liver injury, predominantly by promoting endogenous repair programs
E Yannaki, E Athanasiou, A Xagorari, V Constantinou, I Batsis, P Kaloyannidis, E Proya, A Anagnostopoulos, A Fassas |
Experimental Hematology | 2005 |
|
Nuclear Factor-κB1 (p50) Limits the Inflammatory and Fibrogenic Responses to Chronic Injury
F Oakley, J Mann, S Nailard, DE Smart, N Mungalsingh, C Constandinou, S Ali, SJ Wilson, H Millward-Sadler, JP Iredale, DA Mann |
The American Journal of Pathology | 2005 |
|
Persistence of Liver Cirrhosis in Association with Proliferation of Nonparenchymal Cells and Altered Location of α-Smooth Muscle Actin-Positive Cells
J Kang, K Morimura, E Salim, H Wanibuchi, S Yamaguchi, S Fukushima |
Toxicologic pathology | 2005 |
|
Molecular Pathogenesis of Alcohol-Induced Hepatic Fibrosis:
SV Siegmund, DA Brenner |
Alcoholism: Clinical & Experimental Research | 2005 |
|
Amelioration of microcirculatory damage by an endothelin A receptor antagonist in a rat model of reversible acute liver failure
D Palmes, S Skawran, U Stratmann, B Armann, E Minin, H Herbst, HU Spiegel |
Journal of Hepatology | 2005 |
|
Generation of a monoclonal human single chain antibody fragment to hepatic stellate cells – a potential mechanism for targeting liver anti-fibrotic therapeutics
LJ Elrick, V Leel, MG Blaylock, L Duncan, MR Drever, G Strachan, KA Charlton, M Koruth, AJ Porter, MC Wright |
Journal of Hepatology | 2005 |
|
Oral imatinib treatment reduces early fibrogenesis but does not prevent progression in the long term
M Neef, M Ledermann, H Saegesser, V Schneider, N Widmer, LA Decosterd, B Rochat, J Reichen |
Journal of Hepatology | 2005 |
|
The herbal medicine inchin-ko-to (TJ-135) induces apoptosis in cultured rat hepatic stellate cells
H Ikeda, K Nagashima, M Yanase, T Tomiya, M Arai, Y Inoue, K Tejima, T Nishikawa, N Watanabe, K Kitamura, T Isono, N Yahagi, E Noiri, M Inao, S Mochida, Y Kume, Y Yatomi, K Nakahara, M Omata, K Fujiwara |
Life Sciences | 2005 |
|
Morphological signs of cirrhosis regression
ID Vinicius, AP Baptista, AA Barbosa, ZA Andrade |
Pathology - Research and Practice | 2005 |
|
The plasticity of p19ARF null hepatic stellate cells and the dynamics of activation
V Proell, M Mikula, E Fuchs, W Mikulits |
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research | 2005 |
|
In vivo effects of Chinese herbal recipe, Danshaohuaxian, on apoptosis and proliferation of hepatic stellate cells in hepatic fibrotic rats
Xiao-Xia Geng, Qin Yang, Ru-Jia Xie, Xin-Hua Luo, Bing Han, Li Ma, Cheng-Xiu Li, Ming-Liang Cheng |
2005 | |
|
Effects of interferon-alpha on expression of hepatic stellate cell and transforming growth factor-beta1 and alpha-smooth muscle actin in rats with hepatic fibrosis
Xin-Ming Chang, Ying Chang, Ai Jia |
World journal of gastroenterology : WJG | 2005 |
|
Efficacy of Chinese medicine Yi-gan-kang granule in prophylaxis and treatment of liver fibrosis in rats
Xi-Xian Yao, Shu-Lin Jiang, You-Wei Tang, Dong-Mei Yao, Xin Yao |
World journal of gastroenterology : WJG | 2005 |
|
Effects of augmentation of liver regeneration recombinant plasmid on rat hepatic fibrosis
Qing Li, Dian-Wu Liu, Li-Mei Zhang, Bing Zhu, Yu-Tong He, Yong-Hong Xiao |
World journal of gastroenterology : WJG | 2005 |
|
Effects of fibril- or fixed-collagen on matrix metalloproteinase-1 and tissue inhibitor of matrix metalloproteinase-1 production in the human hepatocyte cell line HLE
Makoto Nakamuta, Kazuhiro Kotoh, Munechika Enjoji, Hajime Nawata |
World journal of gastroenterology : WJG | 2005 |
|
Expression of matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-1 in hepatic stellate cells during rat hepatic fibrosis and its intervention by IL-10
Wei-Da Zheng, Li-Juan Zhang, Mei-Na Shi, Zhi-Xin Chen, Yun-Xin Chen, Yue-Hong Huang, Xiao-Zhong Wang |
World journal of gastroenterology : WJG | 2005 |
|
Effects of interferon-alpha on expression of hepatic stellate cell and transforming growth factor-β1 and α-smooth muscle actin in rats with hepatic fibrosis
XM Chang |
World journal of gastroenterology : WJG | 2005 |
|
Bone marrow-derived mesenchymal stem cells protect against experimental liver fibrosis in rats
Dong-Chang Zhao, Jun-Xia Lei, Rui Chen, Wei-Hua Yu, Xiu-Ming Zhang, Shu-Nong Li, Peng Xiang |
World journal of gastroenterology : WJG | 2005 |
|
Effects of dietary supplementation with vitamin E and selenium on rat hepatic stellate cell apoptosis
Xiu-Hua Shen, Wu-Feng Cheng, Xuan-Hai Li, Jian-Qin Sun, Feng Li, Ling Ma, Liang-Min Xie |
World journal of gastroenterology : WJG | 2005 |
|
Effect of Danshao Huaxian capsule on expression of matrix metalloproteinase-1 and tissue inhibitor of metalloproteinase-1 in fibrotic liver of rats
Qin Yang, Ru-Jia Xie, Xiao-Xia Geng, Xin-Hua Luo, Bing Han, Ming-Liang Cheng |
World journal of gastroenterology : WJG | 2005 |
|
Regressão da fibrose hepática
ZA Andrade |
Revista da Sociedade Brasileira de Medicina Tropical | 2005 |
|
Fibrogenesis in the Pancreas after Acinar Cell Injury
M Patel, DR Fine |
SCAND J SURG | 2005 |
|
Signaling Pathways in Liver Diseases
JF Dufour, PA Clavien, C Trautwein, R Graf |
2005 | |
|
Antioxidant and Antiproliferative Activities of Spirulina and Chlorella Water Extracts
L Wu, JA Ho, MC Shieh, IW Lu |
Journal of Agricultural and Food Chemistry | 2005 |
|
Angiopoietin-1 causes reversible degradation of the portal microcirculation in mice: implications for treatment of liver disease
NL Ward, AL Haninec, PV Slyke, JG Sled, C Sturk, RM Henkelman, IR Wanless, DJ Dumont |
The American Journal of Pathology | 2004 |
|
HIV-Infected Lymphocytes Regulate Fibronectin Synthesis by TGFβ1 Secretion
S Pal, LM Schnapp |
Journal of immunology (Baltimore, Md. : 1950) | 2004 |
|
The nuclear receptor SHP mediates inhibition of hepatic stellate cells by FXR and protects against liver fibrosis
S Fiorucci, E Antonelli, G Rizzo, B Renga, A Mencarelli, L Riccardi, S Orlandi, R Pellicciari, A Morelli |
Gastroenterology | 2004 |
|
Antifibrotic effects of a tissue inhibitor of metalloproteinase-1 antibody on established liver fibrosis in rats
CJ Parsons, BU Bradford, CQ Pan, E Cheung, M Schauer, A Knorr, B Krebs, S Kraft, S Zahn, B Brocks, N Feirt, B Mei, MS Cho, R Ramamoorthi, G Roldan, P Ng, P Lum, C Hirth-Dietrich, A Tomkinson, DA Brenner |
Hepatology | 2004 |
|
Expression of matrix metalloproteinase-2 and -14 persists during early resolution of experimental liver fibrosis and might contribute to fibrolysis
X Zhou, CJ Hovell, S Pawley, MI Hutchings, MJ Arthur, JP Iredale, RC Benyon |
Liver International | 2004 |
|
N-Cadherin cleavage during activated hepatic stellate cell apoptosis is inhibited by tissue inhibitor of metalloproteinase-1
F Murphy, J Waung, J Collins, MJ Arthur, H Nagase, D Mann, RC Benyon, JP Iredale |
Comparative hepatology | 2004 |
|
Lhx2-/- mice develop liver fibrosis
E Wandzioch, A Kolterud, M Jacobsson, SL Friedman, L Carlsson |
Proceedings of the National Academy of Sciences | 2004 |
|
Endothelin receptor antagonist TAK-044 arrests and reverses the development of carbon tetrachloride induced cirrhosis in rats
C Thirunavukkarasu, Y Yang, VM Subbotin, SA Harvey, J Fung, CR Gandhi |
Gut | 2004 |
|
Leptin as a novel profibrogenic cytokine in hepatic stellate cells: mitogenesis and inhibition of apoptosis mediated by extracellular regulated kinase (Erk) and Akt phosphorylation
NK Saxena, MA Titus, X Ding, J Floyd, S Srinivasan, SV Sitaraman, FA Anania |
The FASEB Journal | 2004 |
|
Expression of matrix metalloproteinases and their inhibitors during the resorption of schistosome egg-induced fibrosis in praziquantel-treated mice
KP Singh, HC Gerard, AP Hudson, DL Boros |
Immunology | 2004 |
|
Down-regulation of connective tissue growth factor and type I collagen mRNA expression by connective tissue growth factor antisense oligonucleotide during experimental liver fibrosis
K Uchio, M Graham, NM Dean, J Rosenbaum, A Desmoulière |
Wound Repair and Regeneration | 2004 |
|
Prevention and treatment of hepatic fibrosis at the cellular level
B Stefanovic, J Lindquist, R Rippe, B Schnabl, R Schwabe, R Bataller, D Brenner |
Journal of Gastroenterology and Hepatology | 2004 |
|
Administration of the potent PPAR? agonist, Wy-14,643, reverses nutritional fibrosis and steatohepatitis in mice
E Ip, G Farrell, P Hall, G Robertson, I Leclercq |
Hepatology | 2004 |
|
Enhanced Plasminogen Activator Inhibitor-1 Expression in Transgenic Mice with Hepatocyte-Specific Overexpression of Superoxide Dismutase or Glutathione Peroxidase
K Franke, K Curth, J Lenart, D Knochenhauer, T Kietzmann |
Antioxidants & Redox Signaling | 2004 |
|
Targeted treatments for cirrhosis
JA Fallowfield, JP Iredale |
Expert Opinion on Therapeutic Targets | 2004 |
|
Mechanism of action of the antifibrogenic compound gliotoxin in rat liver cells
JG Orr, V Leel, GA Cameron, CJ Marek, EL Haughton, LJ Elrick, JE Trim, GM Hawksworth, AP Halestrap, MC Wright |
Hepatology | 2004 |
|
Induction of cell death in activated hepatic stellate cells by targeted gene expression of the thymidine kinase/ganciclovir system
N Janoschek, E de Leur, AM Gressner, R Weiskirchen |
Biochemical and Biophysical Research Communications | 2004 |
|
Evaluation of Liver Fibrosis: A Concise Review
NH Afdhal, D Nunes |
The American Journal of Gastroenterology | 2004 |
|
Integration of clinical and gene expression endpoints to explore furan-mediated hepatotoxicity
HK Hamadeh, S Jayadev, ET Gaillard, Q Huang, R Stoll, K Blanchard, J Chou, CJ Tucker, J Collins, R Maronpot, P Bushel, CA Afshari |
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis | 2004 |
|
Histologic recurrence of chronic hepatitis C virus in patients after living donor and deceased donor liver transplantation
ML Shiffman, RT Stravitz, MJ Contos, AS Mills, RK Sterling, VA Luketic, AJ Sanyal, A Cotterell, D Maluf, MP Posner, RA Fisher |
Liver Transplantation | 2004 |
|
Progressive fibrosis during corticosteroid therapy of autoimmune hepatitis
AJ Czaja, HA Carpenter |
Hepatology | 2004 |
|
Clinical, biochemical and imaging-verified regression of hepatitis B-induced cirrhosis
S Massarrat, V Fallahazad, N Kamalian |
Liver International | 2004 |
|
Reversibility of hepatitis C virus-related cirrhosis
S Pol, F Carnot, B Nalpas, JL Lagneau, H Fontaine, J Serpaggi, L Serfaty, P Bedossa, C Bréchot |
Human Pathology | 2004 |
|
Reversibility of cirrhosis in chronic hepatitis B
R Malekzadeh, M Mohamadnejad, N Rakhshani, S Nasseri-Moghaddam, S Merat, SM Tavangar, AA Sohrabpour |
Clinical Gastroenterology and Hepatology | 2004 |
|
The antioxidant and antifibrogenic effects of the glycosaminoglycans hyaluronic acid and chondroitin-4-sulphate in a subchronic rat model of carbon tetrachloride-induced liver fibrogenesis
GM Campo, A Avenoso, S Campo, A D’Ascola, AM Ferlazzo, A Calatroni |
Chemico-Biological Interactions | 2004 |
|
Halofuginone, an inhibitor of collagen synthesis by rat stellate cells, stimulates insulin-like growth factor binding protein-1 synthesis by hepatocytes
Y Gnainsky, G Spira, M Paizi, R Bruck, A Nagler, SN Abu-Amara, B Geiger, O Genina, E Monsonego-Ornan, M Pines |
Journal of Hepatology | 2004 |
|
Superoxide-induced apoptosis of activated rat hepatic stellate cells
C Thirunavukkarasu, S Watkins, SA Harvey, CR Gandhi |
Journal of Hepatology | 2004 |
|
Cirrhosis reversal: a duel between dogma and myth
VJ Desmet, T Roskams |
Journal of Hepatology | 2004 |
|
Thalidomide salvages lethal hepatic necroinflammation and accelerates recovery from cirrhosis in rats
TS Yeh, YP Ho, SF Huang, JN Yeh, YY Jan, MF Chen |
Journal of Hepatology | 2004 |
|
Decreased fibrosis during corticosteroid therapy of autoimmune hepatitis
AJ Czaja, HA Carpenter |
Journal of Hepatology | 2004 |
|
4-Hydroxynonenal as a selective pro-fibrogenic stimulus for activated human hepatic stellate cells
E Zamara, E Novo, F Marra, A Gentilini, RG Romanelli, A Caligiuri, G Robino, E Tamagno, M Aragno, O Danni, R Autelli, S Colombatto, MU Dianzani, M Pinzani, M Parola |
Journal of Hepatology | 2004 |
|
Balance of proliferation and cell death between thyrocytes and myofibroblasts regulates thyroid fibrosis in granulomatous experimental autoimmune thyroiditis (G-EAT)
K Chen, Y Wei, GC Sharp, H Braley-Mullen |
Journal of leukocyte biology | 2004 |
|
N-(methylamino)isobutyric acid inhibits proliferation of CFSC-2C hepatic stellate cells
TL Freeman, GM Thiele, LW Klassen, BT Klassen, ME Mailliard |
Biochemical Pharmacology | 2004 |
|
Treatment of thioacetamide-induced liver cirrhosis by the Ras antagonist, farnesylthiosalicylic acid
S Reif, H Aeed, Y Shilo, R Reich, Y Kloog, YO Kweon, R Bruck |
Journal of Hepatology | 2004 |
|
Hyaluronic acid inhibits adhesion of hepatic stellate cells in spite of its stimulation of DNA synthesis
MK Cho, GH Lee, EY Park, SG Kim |
Tissue and Cell | 2004 |
|
Effect of interleukin-10 and platelet-derived growth factor on expressions of matrix metalloproteinases-2 and tissue inhibitor of metalloproteinases-1 in rat fibrotic liver and cultured hepatic stellate cells
Li-Juan Zhang, Yun-Xin Chen, Zhi-Xin Chen, Yue-Hong Huang, Jie-Ping Yu, Xiao-Zhong Wang |
World journal of gastroenterology : WJG | 2004 |
|
Effects of platelet-derived growth factor and interleukin-10 on Fas/Fas-ligand and Bcl-2/Bax mRNA expression in rat hepatic stellate cells in vitro
Xiao-Zhong Wang, Sheng-Jun Zhang, Yun-Xin Chen, Zhi-Xin Chen, Yue-Hong Huang, Li-Juan Zhang |
World journal of gastroenterology : WJG | 2004 |
|
Relationship between focal adhesion kinase and hepatic stellate cell proliferation during rat hepatic fibrogenesis
Hui-Qing Jiang, Xiao-Lan Zhang, Li Liu, Chang-Chun Yang |
World journal of gastroenterology : WJG | 2004 |
|
Ginkgo biloba extract reverses CCl4 –induced liver fibrosis in rats
Yan-Jun Luo, Jie-Ping Yu, Zhao-Hong Shi, Li Wang |
World journal of gastroenterology : WJG | 2004 |
|
Ginkgo biloba extract reverses CCl4-induced liver fibrosis in rats
Yan-Jun Luo, Jie-Ping Yu, Zhao-Hong Shi, Li Wang |
World journal of gastroenterology : WJG | 2004 |
|
Reversal of Liver Fibrosis and Cirrhosis — An Emerging Reality
JA Fallowfield, JP Iredale |
Scottish Medical Journal | 2004 |
|
Engagement of α v β 3 Integrin Regulates Proliferation and Apoptosis of Hepatic Stellate Cells
X Zhou, FR Murphy, N Gehdu, J Zhang, JP Iredale, RC Benyon |
The Journal of biological chemistry | 2004 |
|
Ginkgo biloba extract reverses CCl 4 –induced liver fibrosis in rats
YJ Luo, JP Yu, ZH Shi, L Wang |
World journal of gastroenterology : WJG | 2004 |
|
TGF-β1 modulates matrix metalloproteinase-13 expression in hepatic stellate cells by complex mechanisms involving p38MAPK, PI3-kinase, AKT, and p70 S6k
CG Lechuga, ZH Hernández-Nazara, JA Rosales, ER Morris, AR Rincón, AM Rivas-Estilla, A Esteban-Gamboa, M Rojkind |
AJP Gastrointestinal and Liver Physiology | 2004 |
|
Vitamin E attenuates biochemical and morphological features associated with development of chronic pancreatitis
JA Gómez, X Molero, E Vaquero, A Alonso, A Salas, JR Malagelada |
AJP Gastrointestinal and Liver Physiology | 2004 |
|
Activation of PPARγ is required for curcumin to induce apoptosis and to inhibit the expression of extracellular matrix genes in hepatic stellate cells in vitro
S ZHENG, A CHEN |
Biochemical Journal | 2004 |
|
Cathepsin B Inactivation Attenuates Hepatic Injury and Fibrosis During Cholestasis
Ali Canbay Maria Eugenia Guicciardi Hajime Higuchi Ariel Feldstein Steven F. Bronk Robert Rydzewski Makiko Taniai Gregory J. Gores |
Journal of Clinical Investigation | 2003 |
|
Treatment of hepatic fibrosis: Almost there
E Albanis, R Safadi, SL Friedman |
Current Gastroenterology Reports | 2003 |
|
Basement membrane-like matrix inhibits proliferation and collagen synthesis by activated rat hepatic stellate cells: evidence for matrix-dependent deactivation of stellate cells
MD Gaça, X Zhou, R Issa, K Kiriella, JP Iredale, RC Benyon |
Matrix Biology | 2003 |
|
Hepatocytes Express Nerve Growth Factor during Liver Injury
F Oakley, N Trim, CM Constandinou, W Ye, AM Gray, G Frantz, K Hillan, T Kendall, RC Benyon, DA Mann, JP Iredale |
The American Journal of Pathology | 2003 |
|
Liver extracellular matrix in health and disease
P Bedossa, V Paradis |
The Journal of Pathology | 2003 |
|
Pathogenesis and management of alcoholic hepatitis
PS Haber, R Warner, D Seth, MD Gorrell, GW Mccaughan |
Journal of Gastroenterology and Hepatology | 2003 |
|
Cirrhosis: new research provides a basis for rational and targeted treatments
JP Iredale |
BMJ (Clinical research ed.) | 2003 |
|
Reciprocal modulation of matrix metalloproteinase-13 and type I collagen genes in rat hepatic stellate cells
B Schaefer, AM Rivas-Estilla, N Meraz-Cruz, MA Reyes-Romero, ZH Hernández-Nazara, JA Domínguez-Rosales, D Schuppan, P Greenwel, M Rojkind |
The American Journal of Pathology | 2003 |
|
Matrix metalloproteinase regulation of sphingosine-1-phosphate-induced angiogenic properties of bone marrow stromal cells
B Annabi, S Thibeault, YT Lee, N Bousquet-Gagnon, N Eliopoulos, S Barrette, J Galipeau, R Béliveau |
Experimental Hematology | 2003 |
|
Identification, expression, and tissue distribution of the three rat lysyl hydroxylase isoforms
DK Mercer, PF Nicol, C Kimbembe, SP Robins |
Biochemical and Biophysical Research Communications | 2003 |
|
Induction of Apoptosis by Tanshinone I via Cytochrome c Release in Activated Hepatic Stellate Cells
JY Kim, KM Kim, JX Nan, YZ Zhao, PH Park, SJ Lee, DH Sohn |
Pharmacology and Toxicology | 2003 |
|
Extracellular Matrix and the Liver
MJ Arthur |
Extracellular Matrix and the Liver | 2003 |
|
Liver fibrosis – from bench to bedside
SL Friedman |
Journal of Hepatology | 2003 |
|
Apoptosis of hepatic stellate cells in carbon tetrachloride induced acute liver injury of the rat: analysis of isolated hepatic stellate cells
JI Lee, KS Lee, YH Paik, YN Park, KH Han, CY Chon, YM Moon |
Journal of Hepatology | 2003 |
|
Adenoviral-mediated transfer of p53 or retinoblastoma protein blocks cell proliferation and induces apoptosis in culture-activated hepatic stellate cells
B Abriss, G Hollweg, AM Gressner, R Weiskirchen |
Journal of Hepatology | 2003 |
|
Lung Biology in Health and Disease
N Zamel |
Lung Biology in Health and Disease: Experimental Models and Therapeutic Potential | 2003 |
|
Nuevos horizontes en los mecanismos de la lesión aguda y crónica del páncreas
X Molero, E Vaquero, JA Gómez, A Alonso, L Guarner |
Gastroenterología y Hepatología | 2003 |
|
Normal and Pathologic Soft Tissue Remodeling: Role of the Myofibroblast, with Special Emphasis on Liver and Kidney Fibrosis
A Desmoulière, IA Darby, G Gabbiani |
Laboratory Investigation | 2003 |
|
Approaches for treatment of liver fibrosis in chronic hepatitis C
P Bedossa, V Paradis |
Clinics in Liver Disease | 2003 |
|
Anti-fibrogenic effects of captopril and candesartan cilexetil on the hepatic fibrosis development in rat
I Tuncer, H Ozbek, S Ugras, I Bayram |
Experimental and Toxicologic Pathology | 2003 |
|
Gliotoxin-mediated apoptosis of activated human hepatic stellate cells
YO Kweon, YH Paik, B Schnabl, T Qian, JJ Lemasters, DA Brenner |
Journal of Hepatology | 2003 |
|
Inhibition of markers of hepatic stellate cell activation by the hormone relaxin
RG Bennett, KK Kharbanda, DJ Tuma |
Biochemical Pharmacology | 2003 |
|
Inhibition on the production of collagen type I, III of activated hepatic stellate cells by antisense TIMP-1 recombinant plasmid
WB Liu |
World journal of gastroenterology : WJG | 2003 |
|
Effects of cytokines on carbon tetrachloride-induced hepatic fibrogenesis in rats
Li-Juan Zhang, Jie-Ping Yu, Dan Li, Yue-Hong Huang, Zhi-Xin Chen, Xiao-Zhong Wang |
World journal of gastroenterology : WJG | 2003 |
|
Cyclooxygenase-2 Inhibits Tumor Necrosis Factor α-mediated Apoptosis in Renal Glomerular Mesangial Cells
A Ishaque, MJ Dunn, A Sorokin |
The Journal of biological chemistry | 2003 |
|
Portal tract fibrogenesis in the liver
G Ramadori, B Saile |
Laboratory Investigation | 2003 |
|
Involvement of Rho/Rho kinase pathway in regulation of apoptosis in rat hepatic stellate cells
H Ikeda, K Nagashima, M Yanase, T Tomiya, M Arai, Y Inoue, K Tejima, T Nishikawa, M Omata, S Kimura, K Fujiwara |
AJP Gastrointestinal and Liver Physiology | 2003 |
|
Conditional tetracycline-regulated expression of TGF-β1 in liver of transgenic mice leads to reversible intermediary fibrosis
E Ueberham |
Hepatology | 2003 |
|
Replicative senescence of activated human hepatic stellate cells is accompanied by a pronounced inflammatory but less fibrogenic phenotype
B Schnabl |
Hepatology | 2003 |
|
Klinische Hepatologie
H Dancygier |
2003 | |
|
Role of apoptosis in the remodeling of cholestatic liver injury following release of the mechanical stress
AM Costa, B Tuchweber, T Lamireau, IM Yousef, C Balabaud, J Rosenbaum, A Desmoulière |
Virchows Archiv | 2003 |
|
Antiapoptotic effect of interferon-α on hepatic stellate cells (HSC): A novel pathway of IFN-α signal transduction via Janus kinase 2 (JAK2) and caspase-8
B Saile, C Eisenbach, H El-Armouche, K Neubauer, G Ramadori |
European Journal of Cell Biology | 2003 |
|
Intracellular Regulation of Fas-Induced Apoptosis in Human Fibroblasts by Extracellular Factors and Cycloheximide
B Santiago, M Galindo, G Palao, JL Pablos |
Journal of immunology (Baltimore, Md. : 1950) | 2003 |
|
Mechanisms of Spontaneous Resolution versus Fibrosis in Granulomatous Experimental Autoimmune Thyroiditis
K Chen, Y Wei, GC Sharp, H Braley-Mullen |
Journal of immunology (Baltimore, Md. : 1950) | 2003 |
|
Mutation in collagen-1 that confers resistance to the action of collagenase results in failure of recovery from CCl4-induced liver fibrosis, persistence of activated hepatic stellate cells, and diminished hepatocyte regeneration
R Issa, X Zhou, N Trim, H Millward-Sadler, S Krane, C Benyon, J Iredale |
The FASEB Journal | 2002 |
|
Mesenchymal cells in the liver - one cell type or two?: Hepatic stellate cells and liver myofibroblasts
G Ramadori, B Saile, G Ramadori, B Saile |
Liver | 2002 |
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Expression of Transforming Growth Factor-β1 by Pancreatic Stellate Cells and Its Implications for Matrix Secretion and Turnover in Chronic Pancreatitis
FW Shek, RC Benyon, FM Walker, PR McCrudden, SL Pender, EJ Williams, PA Johnson, CD Johnson, AC Bateman, DR Fine, JP Iredale |
The American Journal of Pathology | 2002 |
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The antioxidant (-)-epigallocatechin-3-gallate inhibits activated hepatic stellate cell growth and suppresses acetaldehyde-induced gene expression
A Chen, L Zhang, J Xu, J Tang |
Biochemical Journal | 2002 |
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Expression of transforming growth factor-beta 1 by pancreatic stellate cells and its implications for matrix secretion and turnover in chronic pancreatitis
FW Shek, RC Benyon, FM Walker, PR McCrudden, SL Pender, EJ Williams, PA Johnson, CD Johnson, AC Bateman, DR Fine, JP Iredale |
The American Journal of Pathology | 2002 |
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Apoptosis and proliferation of acinar and islet cells in chronic pancreatitis: evidence for differential cell loss mediating preservation of islet function
AC Bateman, SM Turner, KS Thomas, PR McCrudden, DR Fine, PA Johnson, CD Johnson, JP Iredale |
Gut | 2002 |
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Developing strategies for liver fibrosis treatment
F Murphy, M Arthur, J Iredale |
Expert Opinion on Investigational Drugs | 2002 |
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Pathogenic Roles of Tumor Necrosis Factor Receptor p55–Mediated Signals in Dimethylnitrosamine-Induced Murine Liver Fibrosis
K Kitamura, Y Nakamoto, M Akiyama, C Fujii, T Kondo, K Kobayashi, S Kaneko, N Mukaida |
Laboratory Investigation | 2002 |
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Accelerated reversal of carbon tetrachloride-induced cirrhosis in rats by the endothelin receptor antagonist TAK-044
K Anselmi, VM Subbotin, E Nemoto, CR Gandhi |
Journal of Gastroenterology and Hepatology | 2002 |
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Expression of Matrix Metalloproteinases in Cyclosporin-Treated Gingival Fibroblasts Is Regulated by Transforming Growth Factor (TGF)-β1 Autocrine Stimulation
P Cotrim, CR Andrade, H Martelli-Junior, E Graner, JJ Sauk, RD Coletta |
Journal of Periodontology | 2002 |
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Intrahepatic expression of the hepatic stellate cell marker fibroblast activation protein correlates with the degree of fibrosis in hepatitis C virus infection
MT Levy, GW McCaughan, G Marinos, MD Gorrell |
Liver International | 2002 |
|
Normal scarring: importance of myofibroblasts
D Lorena, K Uchio, AM Costa, A Desmouliere |
Wound Repair and Regeneration | 2002 |
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Skin flap-induced regression of granulation tissue correlates with reduced growth factor and increased metalloproteinase expression
IA Darby, T Bisucci, B Pittet, S Garbin, G Gabbiani, A Desmouli�re |
The Journal of Pathology | 2002 |
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Intrasplenic transplantation of syngenic hepatocytes modified by IFN-gamma gene ameliorates hepatic fibrosis in rats
E Song, J Chen, K Wang, H Zhang, F Su, M Wang, U Heemann |
Transplant International | 2002 |
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Oncostatin M stimulates tissue inhibitor of metalloproteinase-1 via a MEK-sensitive mechanism in human myofibroblasts
N Sohara |
Journal of Hepatology | 2002 |
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Reversal of activation of human myofibroblast-like cells by culture on a basement membrane-like substrate
N Sohara, I Znoyko, MT Levy, M Trojanowska, A Reuben |
Journal of Hepatology | 2002 |
|
Nuevas perspectivas terapéuticas de la fibrosis hepática: bases patogénicas
R Bataller, P Ginès |
Medicina Clínica | 2002 |
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Reversibility of liver fibrosis and cirrhosis following treatment for hepatitis C
MJ Arthur |
Gastroenterology | 2002 |
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Mécanismes de la fibrogénèse hépatique
T Lamireau, A Desmoulière, P Bioulac-Sage, J Rosenbaum |
Archives de Pédiatrie | 2002 |
|
Inhibition of hepatic stellate cell collagen synthesis by N-(methylamino)isobutyric acid
TL Freeman, KK Kharbanda, DJ Tuma, ME Mailliard |
Biochemical Pharmacology | 2002 |
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Fas enhances fibrogenesis in the bile duct ligated mouse: A link between apoptosis and fibrosis
A Canbay, H Higuchi, SF Bronk, M Taniai, TJ Sebo, GJ Gores |
Gastroenterology | 2002 |
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Salvia miltiorrhiza monomer IH764-3 induces hepatic stellate cell apoptosis via caspase-3 activation
XL Zhang |
World journal of gastroenterology : WJG | 2002 |
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ROC curves in evaluation of serum fibrosis indices for hepatic fibrosis
M Zheng |
World journal of gastroenterology : WJG | 2002 |
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Effects of Yigan Decoction on proliferation and apoptosis of hepatic stellate cells
XX Yao |
World journal of gastroenterology : WJG | 2002 |
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Review Article: Cystic Degeneration/Spongiosis Hepatis in Rats
E Karbe, RL Kerlin |
Toxicologic pathology | 2002 |
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Sphingosine 1-Phosphate Triggers Both Apoptotic and Survival Signals for Human Hepatic Myofibroblasts
J Davaille, L Li, A Mallat, S Lotersztajn |
The Journal of biological chemistry | 2002 |
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Role of TGF-β1 in the development of pancreatic fibrosis in Otsuka Long-Evans Tokushima Fatty rats
H Yoshikawa, Y Kihara, M Taguchi, T Yamaguchi, H Nakamura, M Otsuki |
AJP Gastrointestinal and Liver Physiology | 2002 |
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Apoptosis of human hepatic myofibroblasts promotes activation of matrix metalloproteinase-2
A Preaux |
Hepatology | 2002 |
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Tissue inhibitor of metalloproteinases-1 attenuates spontaneous liver fibrosis resolution in the transgenic mouse
H Yoshiji |
Hepatology | 2002 |
|
Effects of Yigan Decoction on proliferation and apoptosis of hepatic stellate cells.
Yao XX, Tang YW, Yao DM, Xiu HM |
World Journal of Gastroenterology | 2002 |
|
Salvia miltiorrhiza monomer IH764-3 induces hepatic stellate cell apoptosis via caspase-3 activation.
Zhang XL, Liu L, Jiang HQ |
World Journal of Gastroenterology | 2002 |
|
ROC curves in evaluation of serum fibrosis indices for hepatic fibrosis.
Zheng M, Cai WM, Weng HL, Liu RH |
World Journal of Gastroenterology | 2002 |
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Expression of the peripheral-type benzodiazepine receptor and apoptosis induction in hepatic stellate cells
R Fischer, M Schmitt, JG Bode, D Häussinger |
Gastroenterology | 2001 |
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The up-and-down of hepatic stellate cells in tissue injury: Apoptosis restores cellular homeostasis
AM Gressner |
Gastroenterology | 2001 |
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Apoptosis of hepatic stellate cells: involvement in resolution of biliary fibrosis and regulation by soluble growth factors
R Issa, E Williams, N Trim, T Kendall, MJ Arthur, J Reichen, RC Benyon, JP Iredale |
Gut | 2001 |
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Regulation of E-box DNA binding during in vivo and in vitro activation of rat and human hepatic stellate cells
KJ Vincent, E Jones, MJ Arthur, DE Smart, J Trim, MC Wright, DA Mann |
Gut | 2001 |
|
Apoptosis in Dissociation between DNA Synthesis and Cellular Functions of Activated Hepatic Stellate Cells—A Study with Carbon Tetrachloride-Induced Rat Liver Injury
N Osada, S Mochida, M Inao, Y Mashimo, K Fujiwara |
Biochemical and Biophysical Research Communications | 2001 |
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Use of Corticosteroid Therapy in Autoimmune Hepatitis Resulting in the Resolution of Cirrhosis
IR Wanless |
Journal of Clinical Gastroenterology | 2001 |
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Is Liver Fibrosis Reversible?
PA Bonis, SL Friedman, MM Kaplan |
New England Journal of Medicine | 2001 |
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Plasminogen deficiency results in poor clearance of non-fibrin matrix and persistent activation of hepatic stellate cells after an acute injury
VL Ng, GE Sabla, H Melin-Aldana, N Kelley-Loughnane, JL Degen, JA Bezerra |
Journal of Hepatology | 2001 |
|
Drugs and the Pharmaceutical Sciences: Physical Chemical Biological Methods
C Porter, W Charman |
Drugs and the Pharmaceutical Sciences | 2001 |
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HEPATIC FIBROSIS
E Albanis, SL Friedman |
Clinics in Liver Disease | 2001 |
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Gliotoxin stimulates the apoptosis of human and rat hepatic stellate cells and enhances the resolution of liver fibrosis in rats
MC Wright, R Issa, DE Smart, N Trim, GI Murray, JN Primrose, MJ Arthur, JP Iredale, DA Mann |
Gastroenterology | 2001 |
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TIMP-1 deficiency does not attenuate interstitial fibrosis in obstructive nephropathy
H Kim, T Oda, J López-Guisa, D Wing, DR Edwards, PD Soloway, AA Eddy |
Journal of the American Society of Nephrology : JASN | 2001 |
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Decreasing fibrogenesis: an immunohistochemical study of paired liver biopsies following lamivudine therapy for chronic hepatitis B
YO Kweon, ZD Goodman, JL Dienstag, ER Schiff, NA Brown, E Burkhardt, R Schoonhoven, DA Brenner, MW Fried |
Journal of Hepatology | 2001 |
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Dynamic change of cells expressing MMP-2 mRNA and MT1-MMP mRNA in the recovery from liver fibrosis in the rat
T Watanabe, M Niioka, A Ishikawa, S Hozawa, M Arai, K Maruyama, A Okada, I Okazaki |
Journal of Hepatology | 2001 |
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Myofibroblasts and apoptosis in human hypertrophic scars: The effect of interferon-α2b
B Nedelec, H Shankowsky, PG Scott, A Ghahary, EE Tredget |
Surgery | 2001 |
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Effects of hypoxia, hyperoxia on the regulation of expression and activity of matrix metalloproteinase-2 in hepatic stellate cells
Ping-Sheng Chen, Wei-Rong Zhai, Xiao-Mei Zhou, Jin-Sheng Zhang, Yue-E Zhang, Yu-Qin Ling, Ying-Hong Gu |
World journal of gastroenterology : WJG | 2001 |
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Inhibiting effect of antisense oligonucleotides phosphorthioate on gene expression of TIMP-1 in rat liver fibrosis
QH Nie |
World journal of gastroenterology : WJG | 2001 |
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Physiology of Inflammation
K Ley |
2001 | |
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Liver Cirrhosis
K Okita |
2001 | |
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Inhibiting effect of antisense oligonucleotides phosphorthioate on gene expression of TIMP-1 in rat liver fibrosis.
Nie QH, Cheng YQ, Xie YM, Zhou YX, Cao YZ |
World Journal of Gastroenterology | 2001 |
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Effects of hypoxia, hyperoxia on the regulation of expression and activity of matrix metalloproteinase-2 in hepatic stellate cells.
Chen PS, Zhai WR, Zhou XM, Zhang JS, Zhang YE, Ling YQ, Gu YH |
World Journal of Gastroenterology | 2001 |
|
Liver fibrosis
M Pinzani |
Springer Seminars in Immunopathology | 2000 |
|
Interstitial fibrosis in mice with overload proteinuria: Deficiency of TIMP-1 is not protective
AA Eddy, H Kim, J López-Guisa, T Oda, PD Soloway, L Mcculloch, E Liu, D Wing |
Kidney International | 2000 |
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Molecular mechanism of the reversibility of hepatic fibrosis: With special reference to the role of matrix metalloproteinases
I Okazaki, T Watanabe, S Hozawa, M Arai, K Maruyama |
Journal of Gastroenterology and Hepatology | 2000 |
|
Hepatic Stellate Cells Express the Low Affinity Nerve Growth Factor Receptor p75 and Undergo Apoptosis in Response to Nerve Growth Factor Stimulation
N Trim, S Morgan, M Evans, R Issa, D Fine, S Afford, B Wilkins, J Iredale |
The American Journal of Pathology | 2000 |
|
Is liver fibrosis reversible?
RC Benyon, JP Iredale |
Gut | 2000 |
|
Triple-Staining to Identify Apoptosis of Hepatic Cells In Situ
J Zhang, H You, T Wang, B Wang, J Jia, H Katayama, S Maeda, R Wang, G Asano, T Ishiwata, Z Naito, M Yokoyama |
Journal of Nippon Medical School | 2000 |
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Repetitive Acute Pancreatic Injury in the Mouse Induces Procollagen α1(I) Expression Colocalized to Pancreatic Stellate Cells
BA Neuschwander-Tetri, KR Bridle, LD Wells, M Marcu, GA Ramm |
Laboratory Investigation | 2000 |
|
Increased toxin-induced liver injury and fibrosis in interleukin-6-deficient mice
K Kovalovich, RA DeAngelis, W Li, EE Furth, G Ciliberto, R Taub |
Hepatology | 2000 |
|
Hypoxia promotes fibrogenesis in human renal fibroblasts
JT Norman, IM Clark, PL Garcia |
Kidney International | 2000 |
|
Stress-activated protein kinases in the activation of rat hepatic stellate cells in culture
HL Reeves, CL Dack, M Peak, AD Burt, CP Day |
Journal of Hepatology | 2000 |
|
Nuclear factor κB in proliferation, activation, and apoptosis in rat hepatic stellate cells
A Lang, R Schoonhoven, S Tuvia, DA Brenner, RA Rippe |
Journal of Hepatology | 2000 |
|
Gene expression of interstitial collagenase in both progressive and recovery phase of rat liver fibrosis induced by carbon tetrachloride
T Watanabe, M Niioka, S Hozawa, K Kameyama, T Hayashi, M Arai, A Ishikawa, K Maruyama, I Okazaki |
Journal of Hepatology | 2000 |
|
Decorin and actin expression and distribution in patients with chronic hepatitis C following interferon-alfa-2b treatment
K Jármay, M Gallai, G Karácsony, Z Ozsvár, Z Schaff, J Lonovics, I Kovalszky |
Journal of Hepatology | 2000 |
|
THE CELL AND MOLECULAR BIOLOGY OF HEPATIC FIBROGENESIS
DC Rockey |
Clinics in Liver Disease | 2000 |
|
Activated macrophages direct apoptosis and suppress mitosis of mesangial cells
JS Duffield, LP Erwig, X Wei, FY Liew, AJ Rees, JS Savill |
Journal of immunology (Baltimore, Md. : 1950) | 2000 |
|
Matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-1 expression in fibrotic rat liver
HL Liu |
World journal of gastroenterology : WJG | 2000 |
|
Upstream Tissue Inhibitor of Metalloproteinases-1 (TIMP-1) Element-1, a Novel and Essential Regulatory DNA Motif in the Human TIMP-1 Gene Promoter, Directly Interacts with a 30-kDa Nuclear Protein
JE Trim, SK Samra, MJ Arthur, MC Wright, M McAulay, R Beri, DA Mann |
The Journal of biological chemistry | 2000 |
|
Molecular Regulation of Hepatic Fibrosis, an Integrated Cellular Response to Tissue Injury
SL Friedman |
The Journal of biological chemistry | 2000 |
|
Fibrogenesis II. Metalloproteinases and their inhibitors in liver fibrosis
MJ Arthur |
AJP Gastrointestinal and Liver Physiology | 2000 |
|
Fibrogenesis I. New insights into hepatic stellate cell activation: the simple becomes complex
FJ Eng, SL Friedman |
AJP Gastrointestinal and Liver Physiology | 2000 |
|
Tissue inhibitor of metalloproteinases-1 promotes liver fibrosis development in a transgenic mouse model: Tissue inhibitor of metalloproteinases-1 promotes liver fibrosis development in a transgenic mouse model
H Yoshiji, S Kuriyama, Y Miyamoto, UP Thorgeirsson, DE Gomez, M Kawata, J Yoshii, Y Ikenaka, R Noguchi, H Tsujinoue, T Nakatani, SS Thorgeirsson, H Fukui |
Hepatology | 2000 |
|
Mechanisms and therapy of hepatic fibrosis: Report of the AASLD single topic basic research conference: Mechanisms and therapy of hepatic fibrosis: Report of the AASLD single topic basic research conference
SL Friedman, JJ Maher, DM Bissell |
Hepatology | 2000 |
|
CONTROL OF WOUND CONTRACTION
B Nedelec, A Ghahary, PG Scott, EE Tredget |
Hand Clinics | 2000 |
|
Regression of Human Cirrhosis
IR Wanless, E Nakashima, M Sherman |
Archives of pathology & laboratory medicine | 2000 |
|
Matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-1 expression in fibrotic rat liver.
Liu HL, Li XH, Wang DY, Yang SP |
World Journal of Gastroenterology | 2000 |
|
Tissue Inhibitors of Metalloproteinases: Role in Liver Fibrosis and Alcoholic Liver Disease
MJ Arthur, JP Iredale, DA Mann |
Alcoholism, clinical and experimental research | 1999 |
|
The significance of apoptosis in the liver
A Benedetti, L Marucci |
Liver International | 1999 |
|
Role of Metalloproteinases in Liver Fibrosis
M Rojkind |
Alcoholism, clinical and experimental research | 1999 |
|
The metalloproteinase matrilysin proteolytically generates active soluble Fas ligand and potentiates epithelial cell apoptosis
WC Powell, B Fingleton, CL Wilson, M Boothby, LM Matrisian |
Current Biology | 1999 |
|
The virtuosity of hepatic stellate cells
SL Friedman |
Gastroenterology | 1999 |
|
Myofibroblasts. I. Paracrine cells important in health and disease
D Li, SL Friedman |
The American journal of physiology | 1999 |
|
Selective Sensitization to Tumor Necrosis Factor-α-induced Apoptosis by Blockade of NF-κB in Primary Glomerular Mesangial Cells
H Sugiyama, JS Savill, M Kitamura, L Zhao, E Stylianou |
The Journal of biological chemistry | 1999 |
|
Persistent activation of nuclear factor-?B in cultured rat hepatic stellate cells involves the induction of potentially novel rel-like factors and prolonged changes in the expression of I?B family proteins
AM Elsharkawy, MC Wright, RT Hay, MJ Arthur, T Hughes, MJ Bahr, K Degitz, DA Mann |
Hepatology | 1999 |
|
Transforming growth factor ? and tumor necrosis factor ? inhibit both apoptosis and proliferation of activated rat hepatic stellate cells
B Saile, N Matthes, T Knittel, G Ramadori |
Hepatology | 1999 |
|
Gene therapy for hepatic fibrosis?bringing treatment into the new millennium
DC Rockey |
Hepatology | 1999 |
|
Alkohol und Alkoholfolgekrankheiten
MV Singer, S Teyssen |
1999 | |
|
Alteration in expression of MMP-1 and MMP-2 but not TIMP-1 and TIMP-2 in hereditary gingival fibromatosis is mediated by TGF-beta1 autocrine stimulation
RD Coletta, OP Almeida, MA Reynolds, JJ Sauk |
Journal of Periodontal Research | 1999 |
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Principles of Medical Biology
JO Jørgensen |
Principles of Medical Biology | 1998 |
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Molecular regulation of hepatic fibrogenesis
E Olaso, SL Friedman |
Journal of Hepatology | 1998 |
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Advances in Pharmacology
B Drenger, Y Ginosar, Y Gozal |
Advances in Pharmacology | 1994 |
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Holeuryhalinity and its mechanisms in a cirriped crustacean, Balanus improvisus.
Fyhn HJ |
Comparative Biochemistry and Physiology Part A Physiology | 1976 |
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