Go to JCI Insight
  • About
  • Editors
  • Consulting Editors
  • For authors
  • Publication ethics
  • Publication alerts by email
  • Advertising
  • Job board
  • Contact
  • Clinical Research and Public Health
  • Current issue
  • Past issues
  • By specialty
    • COVID-19
    • Cardiology
    • Gastroenterology
    • Immunology
    • Metabolism
    • Nephrology
    • Neuroscience
    • Oncology
    • Pulmonology
    • Vascular biology
    • All ...
  • Videos
    • Conversations with Giants in Medicine
    • Video Abstracts
  • Reviews
    • View all reviews ...
    • Complement Biology and Therapeutics (May 2025)
    • Evolving insights into MASLD and MASH pathogenesis and treatment (Apr 2025)
    • Microbiome in Health and Disease (Feb 2025)
    • Substance Use Disorders (Oct 2024)
    • Clonal Hematopoiesis (Oct 2024)
    • Sex Differences in Medicine (Sep 2024)
    • Vascular Malformations (Apr 2024)
    • View all review series ...
  • Viewpoint
  • Collections
    • In-Press Preview
    • Clinical Research and Public Health
    • Research Letters
    • Letters to the Editor
    • Editorials
    • Commentaries
    • Editor's notes
    • Reviews
    • Viewpoints
    • 100th anniversary
    • Top read articles

  • Current issue
  • Past issues
  • Specialties
  • Reviews
  • Review series
  • Conversations with Giants in Medicine
  • Video Abstracts
  • In-Press Preview
  • Clinical Research and Public Health
  • Research Letters
  • Letters to the Editor
  • Editorials
  • Commentaries
  • Editor's notes
  • Reviews
  • Viewpoints
  • 100th anniversary
  • Top read articles
  • About
  • Editors
  • Consulting Editors
  • For authors
  • Publication ethics
  • Publication alerts by email
  • Advertising
  • Job board
  • Contact
Top
  • View PDF
  • Download citation information
  • Send a comment
  • Terms of use
  • Standard abbreviations
  • Need help? Email the journal
  • Top
  • Version history
  • Article usage
  • Citations to this article (8)

Advertisement

Research Article Free access | 10.1172/JCI101641

THE USE OF PENICILLIN IN THE LOCAL TREATMENT OF PNEUMOCOCCAL EMPYEMA

William S. Tillett, James E. McCormack, and Margaret J. Cambier

Department of Medicine of New York University College of Medicine, New York City

Third Medical Division of Bellevue Hospital, New York City

1

This investigation was aided in part by the Commission on Pneumonia, Board for the Investigation and Control of Influenza and Other Epidemic Diseases in the Army, Preventive Medicine Service, Office of the Surgeon General, U. S. Army.

2

The penicillin was provided by the Office of Scientific Research and Development from supplies assigned by the Committee on Medical Research for clinical investigations recommended by the Committee on Chemotherapeutic and Other Agents of the National Research Council.

Find articles by Tillett, W. in: PubMed | Google Scholar

Department of Medicine of New York University College of Medicine, New York City

Third Medical Division of Bellevue Hospital, New York City

1

This investigation was aided in part by the Commission on Pneumonia, Board for the Investigation and Control of Influenza and Other Epidemic Diseases in the Army, Preventive Medicine Service, Office of the Surgeon General, U. S. Army.

2

The penicillin was provided by the Office of Scientific Research and Development from supplies assigned by the Committee on Medical Research for clinical investigations recommended by the Committee on Chemotherapeutic and Other Agents of the National Research Council.

Find articles by McCormack, J. in: PubMed | Google Scholar

Department of Medicine of New York University College of Medicine, New York City

Third Medical Division of Bellevue Hospital, New York City

1

This investigation was aided in part by the Commission on Pneumonia, Board for the Investigation and Control of Influenza and Other Epidemic Diseases in the Army, Preventive Medicine Service, Office of the Surgeon General, U. S. Army.

2

The penicillin was provided by the Office of Scientific Research and Development from supplies assigned by the Committee on Medical Research for clinical investigations recommended by the Committee on Chemotherapeutic and Other Agents of the National Research Council.

Find articles by Cambier, M. in: PubMed | Google Scholar

Published July 1, 1945 - More info

Published in Volume 24, Issue 4 on July 1, 1945
J Clin Invest. 1945;24(4):595–610. https://doi.org/10.1172/JCI101641.
© 1945 The American Society for Clinical Investigation
Published July 1, 1945 - Version history
View PDF
Browse pages

Click on an image below to see the page. View PDF of the complete article

icon of scanned page 595
page 595
icon of scanned page 596
page 596
icon of scanned page 597
page 597
icon of scanned page 598
page 598
icon of scanned page 599
page 599
icon of scanned page 600
page 600
icon of scanned page 601
page 601
icon of scanned page 602
page 602
icon of scanned page 603
page 603
icon of scanned page 604
page 604
icon of scanned page 605
page 605
icon of scanned page 606
page 606
icon of scanned page 607
page 607
icon of scanned page 608
page 608
icon of scanned page 609
page 609
icon of scanned page 610
page 610
Version history
  • Version 1 (July 1, 1945): No description

Article tools

  • View PDF
  • Download citation information
  • Send a comment
  • Terms of use
  • Standard abbreviations
  • Need help? Email the journal

Metrics

  • Article usage
  • Citations to this article (8)

Go to

  • Top
  • Version history
Advertisement
Advertisement

Copyright © 2025 American Society for Clinical Investigation
ISSN: 0021-9738 (print), 1558-8238 (online)

Sign up for email alerts