Review Series

On diabetes: insulin resistance

Series edited by Alan R. Saltiel

Type 2 diabetes is a progressive disease that starts with peripheral insulin resistance, which in itself is a key feature of other human disease states. The series outlines the complex pathophysiology of insulin resistance, including the connections to obesity and cardiovascular disease.

Articles in series

Series Introduction: The molecular and physiological basis of insulin resistance: emerging implications for metabolic and cardiovascular diseases
Alan R. Saltiel
Alan R. Saltiel
Published January 15, 2000
Citation Information: J Clin Invest. 2000;106(2):163-164. https://doi.org/10.1172/JCI10533.
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Signaling pathways in insulin action: molecular targets of insulin resistance
Jeffrey E. Pessin, Alan R. Saltiel
Jeffrey E. Pessin, Alan R. Saltiel
Published January 15, 2000
Citation Information: J Clin Invest. 2000;106(2):165-169. https://doi.org/10.1172/JCI10582.
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Cellular mechanisms of insulin resistance
Gerald I. Shulman
Gerald I. Shulman
Published January 15, 2000
Citation Information: J Clin Invest. 2000;106(2):171-176. https://doi.org/10.1172/JCI10583.
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Cellular mechanisms of insulin resistance

Abstract

Authors

Gerald I. Shulman

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Strategies and prospects for finding insulin resistance genes
Michael P. Stern
Michael P. Stern
Published August 1, 2000
Citation Information: J Clin Invest. 2000;106(3):323-327. https://doi.org/10.1172/JCI10725.
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Interactions between insulin resistance and insulin secretion in the development of glucose intolerance
Melissa K. Cavaghan, … , David A. Ehrmann, Kenneth S. Polonsky
Melissa K. Cavaghan, … , David A. Ehrmann, Kenneth S. Polonsky
Published August 1, 2000
Citation Information: J Clin Invest. 2000;106(3):329-333. https://doi.org/10.1172/JCI10761.
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Interactions between insulin resistance and insulin secretion in the development of glucose intolerance

Abstract

Authors

Melissa K. Cavaghan, David A. Ehrmann, Kenneth S. Polonsky

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Insulin resistance and cardiovascular disease
Henry N. Ginsberg
Henry N. Ginsberg
Published August 15, 2000
Citation Information: J Clin Invest. 2000;106(4):453-458. https://doi.org/10.1172/JCI10762.
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Insulin resistance and cardiovascular disease

Abstract

Authors

Henry N. Ginsberg

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Insights into insulin resistance and type 2 diabetes from knockout mouse models
Takashi Kadowaki
Takashi Kadowaki
Published August 15, 2000
Citation Information: J Clin Invest. 2000;106(4):459-465. https://doi.org/10.1172/JCI10830.
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Treatment of insulin resistance with peroxisome proliferator–activated receptor γ agonists
Jerrold M. Olefsky
Jerrold M. Olefsky
Published August 15, 2000
Citation Information: J Clin Invest. 2000;106(4):467-472. https://doi.org/10.1172/JCI10843.
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Obesity and insulin resistance
Barbara B. Kahn, Jeffrey S. Flier
Barbara B. Kahn, Jeffrey S. Flier
Published August 15, 2000
Citation Information: J Clin Invest. 2000;106(4):473-481. https://doi.org/10.1172/JCI10842.
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Obesity and insulin resistance

Abstract

Authors

Barbara B. Kahn, Jeffrey S. Flier

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