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Citation Information: J Clin Invest. 1982;69(2):358-367. https://doi.org/10.1172/JCI110459.
Abstract
Two sodium transport systems have been analyzed in this work: the voltage-sensitive sodium channel and the (Na+, K+) ATPase pump. The sodium channel has been studied using a tritiated derivative of tetrodotoxin; the sodium pump has been studied using tritiated ouabain. Properties of interaction of tritiated tetrodotoxin and of tritiated ouabain with their respective receptors were observed in normal human skeletal muscle and in muscles of patients with myotonic muscular dystrophy and with lower motor neuron impairment.
Authors
C. Desnuelle, A. Lombet, G. Serratrice, M. Lazdunski
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