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Lawrence C. Panasci, … , Dianna Green, Philip S. Schein
Citation Information: J Clin Invest. 1979;64(4):1103-1111. https://doi.org/10.1172/JCI109549.
Lawrence C. Panasci, … , Dianna Green, Philip S. Schein
Published October 1, 1979
Citation Information: J Clin Invest. 1979;64(4):1103-1111. https://doi.org/10.1172/JCI109549.
Abstract
Chlorozotocin is a chloroethyl nitrosourea with a glucose carrier that has curative activity for the murine L1210 leukemia, but is nonmyelosuppressive in mice. To determine the mechanism for this unique property of reduced bone marrow toxicity, comparative studies were conducted with chlorozotocin and CCNU, a myelotoxic chloroethyl nitrosourea.
Authors
Lawrence C. Panasci, Dianna Green, Philip S. Schein
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