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Citation Information: J Clin Invest. 1974;53(5):1326-1334. https://doi.org/10.1172/JCI107680.
Abstract
A new, specific, and simple method for the determination of δ-aminolevulinic acid (ALA) synthetase activity in human bone marrow cells has been developed. ALA synthetase of erythroblasts was partially purified so as to permit the use of [14C]succinyl-CoA as a substrate for this enzyme. In this enzyme preparation there were negligible activities of succinyl-CoA hydrolase, α-ketoglutarate dehydrogenase, and succinyl-CoA synthetase and there was no activity of ALA dehydrase.
Authors
Yosuke Aoki, Gumpei Urata, Osamu Wada, Fumimaro Takaku
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