Submit a comment
David E. Jenkins Jr., … , Robert C. Hartmann, Albert L. Kerns
Citation Information: J Clin Invest. 1967;46(5):753-761. https://doi.org/10.1172/JCI105576.
David E. Jenkins Jr., … , Robert C. Hartmann, Albert L. Kerns
Published May 1, 1967
Citation Information: J Clin Invest. 1967;46(5):753-761. https://doi.org/10.1172/JCI105576.
Abstract
Complement coating and hemolysis were observed when erythrocytes from patients with paroxysmal nocturnal hemoglobinuria (PNH) were incubated in isotonic sucrose solution in the presence of small amounts of serum. Normal cells were likewise coated with complement components but did not hemolyze. Both normal and PNH erythrocytes reduced the hemolytic complement activity of the serum used in this reaction.
Authors
David E. Jenkins Jr., Robert C. Hartmann, Albert L. Kerns
Guidelines
The Editorial Board will only consider comments that are deemed relevant and of interest to readers. The Journal will not post data that have not been subjected to peer review; or a comment that is essentially a reiteration of another comment.
- Comments appear on the Journal’s website and are linked from the original article’s web page.
- Authors are notified by email if their comments are posted.
- The Journal reserves the right to edit comments for length and clarity.
- No appeals will be considered.
- Comments are not indexed in PubMed.
Specific requirements
- Maximum length, 400 words
- Entered as plain text or HTML
- Author’s name and email address, to be posted with the comment
- Declaration of all potential conflicts of interest (even if these are not ultimately posted); see the Journal’s conflict-of-interest policy
- Comments may not include figures
Copyright © 2024 American Society for Clinical Investigation
ISSN: 0021-9738 (print), 1558-8238 (online)