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Advancing chemokine research: the molecular function of CXCL8
Yiran Hou, Anna Huttenlocher
Yiran Hou, Anna Huttenlocher
Published May 15, 2024
Citation Information: J Clin Invest. 2024;134(10):e180984. https://doi.org/10.1172/JCI180984.
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100th Anniversary Viewpoints Article has an altmetric score of 1

Advancing chemokine research: the molecular function of CXCL8

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Abstract

Authors

Yiran Hou, Anna Huttenlocher

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Figure 1

CXCL8 concentration gradient determines neutrophil migration pattern.

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CXCL8 concentration gradient determines neutrophil migration pattern.
Ne...
Neutrophils migrate toward regions with higher concentrations of CXCL8 when the CXCL8 gradient ranges from low to medium concentrations. This directionality can reverse when there are high concentrations of CXCL8.

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