Discrepancies between the Doses of Cholecystokinin or Caerulein-Stimulating Exocrine and Endocrine Responses in Perfused Isolated Rat Pancreas

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Abstract

The effects of highly purified natural porcine cholecystokinin (CCK) and synthetic caerulein on the rate of flow of pancreatic juice, the rate of output of amylase, and the rate of release of immunoreactive insulin (IRI) and immunoreactive glucagon (IRG) were simultaneously investigated in the isolated perfused rat pancreas.

Authors

Makoto Otsuki, Choitsu Sakamoto, Hosai Yuu, Mitsuo Maeda, Soichiro Morita, Atsuhi Ohki, Noboru Kobayashi, Katsuhiro Terashi, Kuniyasu Okano, Shigeaki Baba