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Concise Publication Free access | 10.1172/JCI107636
Department of Medicine, University of Washington School of Medicine, Seattle, Washington 98195
United States Public Health Service Hospital, Seattle, Washington 98114
Harborview Medical Center, Seattle, Washington 98104
Veteran's Administration Hospital, Seattle, Washington 98108
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Department of Medicine, University of Washington School of Medicine, Seattle, Washington 98195
United States Public Health Service Hospital, Seattle, Washington 98114
Harborview Medical Center, Seattle, Washington 98104
Veteran's Administration Hospital, Seattle, Washington 98108
Find articles by Robinett, B. in: JCI | PubMed | Google Scholar
Department of Medicine, University of Washington School of Medicine, Seattle, Washington 98195
United States Public Health Service Hospital, Seattle, Washington 98114
Harborview Medical Center, Seattle, Washington 98104
Veteran's Administration Hospital, Seattle, Washington 98108
Find articles by Graham, T. in: JCI | PubMed | Google Scholar
Department of Medicine, University of Washington School of Medicine, Seattle, Washington 98195
United States Public Health Service Hospital, Seattle, Washington 98114
Harborview Medical Center, Seattle, Washington 98104
Veteran's Administration Hospital, Seattle, Washington 98108
Find articles by Adamson, J. in: JCI | PubMed | Google Scholar
Department of Medicine, University of Washington School of Medicine, Seattle, Washington 98195
United States Public Health Service Hospital, Seattle, Washington 98114
Harborview Medical Center, Seattle, Washington 98104
Veteran's Administration Hospital, Seattle, Washington 98108
Find articles by Storb, R. in: JCI | PubMed | Google Scholar
Published March 1, 1974 - More info
Two normal collie dogs were given 1,200 R total body irradiation followed by successful marrow grafts from their grey collie littermates with cyclic hematopoiesis. During observation periods of 97 and 41 days after grafting, both previously normal recipients showed regular cyclic fluctuations of their granulocyte and reticulocyte counts similar to those observed in their donors. These findings suggest that canine cyclic neutropenia is due to a defect in the marrow stem cell.
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