Citations to this article

Measurement of Inorganic Pyrophosphate in Biological Fluids, ELEVATED LEVELS IN SOME PATIENTS WITH OSTEOARTHRITIS, PSEUDOGOUT, ACROMEGALY, AND UREMIA
Donald C. Silcox, Daniel J. McCarty
Donald C. Silcox, Daniel J. McCarty
Published August 1, 1973
Citation Information: J Clin Invest. 1973;52(8):1863-1870. https://doi.org/10.1172/JCI107369.
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Research Article

Measurement of Inorganic Pyrophosphate in Biological Fluids, ELEVATED LEVELS IN SOME PATIENTS WITH OSTEOARTHRITIS, PSEUDOGOUT, ACROMEGALY, AND UREMIA

Abstract

A rapid and relatively simple method for measurement of inorganic pyrophosphate (PPi) in biological samples has been described. The mean ±SEM of plasma samples from 94 normal subjects was 1.8±0.06 μM, giving a normal range (99% confidence limits) of 0.16 - 3.40 μmol/liter. Analysis of 17 plasma samples in duplicate showed a standard deviation of 0.18, giving a 99% probability that a single determination of plasma PPi would be ±0.68 μM of the true value.

Authors

Donald C. Silcox, Daniel J. McCarty

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