Effect of dl-ethionine on the intestinal absorption and transport of palmitic acid-1-¹⁴C and tripalmitin-¹⁴C. Role of intramucosal factors in the uptake of luminal lipids

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Abstract

The effect of DL-ethionine on the uptake and transport of lipid by the rat small intestine was investigated. A cottonseed oil emulsion containing 14C-labeled tripalmitin or palmitic acid was administered intragastrically to rats pretreated with DL-ethionine, DL-ethionine plus methionine, or saline, and the rats were sacrificed 2, 4, and 6 hr later. Lipids from the plasma, the stomach, the colon, the luminal contents of the small intestine, and the wall of the small intestine were extracted, fractionated, and their radioactivity assayed.

Authors

Jacques I. Kessler, S. Mishkin, J. Stein