Erythrocytosis associated with hemoglobin Rainier: oxygen equilibria and marrow regulation

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Abstract

Hemoglobin Rainier (β145 tyrosine→histidine) is an abnormal hemoglobin associated with increased oxygen affinity, decreased heme-heme interaction, presence of a Bohr effect, and erythrocytosis, but without obvious clinical sequelae.

Authors

John W. Adamson, Julian T. Parer, George Stamatoyannopoulos, S. Heinenberg