Usage Information

Effect of changes in renal perfusion pressure on the suppression of proximal tubular sodium reabsorption due to saline loading
Norman Bank, … , Hagop S. Aynedjian, Marc Aras
Norman Bank, … , Hagop S. Aynedjian, Marc Aras
Published February 1, 1969
Citation Information: J Clin Invest. 1969;48(2):271-283. https://doi.org/10.1172/JCI105983.
View: Text | PDF
Research Article

Effect of changes in renal perfusion pressure on the suppression of proximal tubular sodium reabsorption due to saline loading

Abstract

Rapid intravenous infusion of saline is known to suppress reabsorption of sodium and water in the proximal tubule. It has previously been shown that this suppression is accompanied by two changes which in combination might account for the over-all decrease in reabsorption: a reduction in the intrinsic reabsorptive capacity of the tubular epithelium (C/πr2) and a reduction in the ratio between tubular volume and GFR (πr2d/Vo). The present micropuncture experiments were carried out in order to study the possible role of altered peritubular physical forces (hydrostatic and colloid oncotic pressure) in mediating these two changes. Proximal tubular reabsorptive capacity, transit time, fractional reabsorption of sodium and water, πr2d/Vo, and intratubular hydrostatic pressure were measured in saline-loaded rats during acute changes in renal perfusion pressure induced by intermittent constriction of the abdominal aorta.

Authors

Norman Bank, Karl M. Koch, Hagop S. Aynedjian, Marc Aras

×

Usage data is cumulative from February 2024 through February 2025.

Usage JCI PMC
Text version 109 0
PDF 50 13
Scanned page 442 6
Citation downloads 52 0
Totals 653 19
Total Views 672
(Click and drag on plot area to zoom in. Click legend items above to toggle)

Usage information is collected from two different sources: this site (JCI) and Pubmed Central (PMC). JCI information (compiled daily) shows human readership based on methods we employ to screen out robotic usage. PMC information (aggregated monthly) is also similarly screened of robotic usage.

Various methods are used to distinguish robotic usage. For example, Google automatically scans articles to add to its search index and identifies itself as robotic; other services might not clearly identify themselves as robotic, or they are new or unknown as robotic. Because this activity can be misinterpreted as human readership, data may be re-processed periodically to reflect an improved understanding of robotic activity. Because of these factors, readers should consider usage information illustrative but subject to change.

Advertisement