The effect of azathioprine therapy on gammaglobulin synthesis was evaluated in nine patients with rheumatic disorders. The rates of synthesis of IgG and IgM were calculated before and after 4 months of azathioprine treatment using turnover studies of radioiodinated gammaglobulins.
Joshua Levy, Eugene V. Barnett, Norman S. MacDonald, James R. Klinenberg, Carl M. Pearson
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